Primary Site >> Colorectal Cancer
Gene >> APC2
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Ref: Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. PMID: 10021369 |
Ref: Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain Protein AIE-75. PMID: 11311560 |
Ref: Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. PMID: 11923210 Ref: Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. PMID: 12297097 Ref: Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. PMID: 12297098 |
Ref: Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. PMID: 18716850 |
Ref: Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans. PMID: 19190129 Ref: Distinct high-profile methylated genes in colorectal cancer. PMID: 19750230 |
Ref: [Effect of recombinant pEGFP-N3-APC vectors carrying various APC functional domains on the expression of beta-catenin in HT-29 cells]. PMID: 20197613 |
Ref: High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients. PMID: 21455633 |
Ref: Defining components of the ss-catenin destruction complex and exploring its regulation and mechanisms of action during development. PMID: 22359584 Ref: Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization. PMID: 22513088 |
Ref: Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer. PMID: 23271133 Ref: Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation. PMID: 23840886 |
Ref: Testing models of the APC tumor suppressor/beta-catenin interaction reshapes our view of the destruction complex in Wnt signaling. PMID: 24931405 |
Ref: The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling. PMID: 26446838 |
Ref: The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the beta-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2. PMID: 27068743 Ref: Proteomic analysis reveals APC-dependent post-translational modifications and identifies a novel regulator of beta-catenin. PMID: 27287809 |
Ref: A novel microRNA located in the TrkC gene regulates the Wnt signaling pathway and is differentially expressed in colorectal cancer specimens. PMID: 28100780 Ref: Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population. PMID: 28761377 |
Ref: Introduction of hsa-miR-103a and hsa-miR-1827 and hsa-miR-137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma. PMID: 28817181 |