Literatures

Primary Site >> Colorectal Cancer

Gene >> APC

1.
Journal:	Cancer Res. 1992 Feb 1;52(3):643-5.
Title:	Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.
Author:	Miki, Y\|Nishisho, I\|Horii, A\|Miyoshi, Y\|Utsunomiya, J\|Kinzler, K W\|Vogelstein, B\|Nakamura, Y
PMID:	1310068

2.
Journal:	Hum Mol Genet. 1992 Nov;1(8):559-63.
Title:	Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma.
Author:	Nakatsuru, S\|Yanagisawa, A\|Ichii, S\|Tahara, E\|Kato, Y\|Nakamura, Y\|Horii, A
PMID:	1338691

3.
Journal:	Cancer Res. 1992 Dec 1;52(23):6696-8.
Title:	Frequent somatic mutations of the APC gene in human pancreatic cancer.
Author:	Horii, A\|Nakatsuru, S\|Miyoshi, Y\|Ichii, S\|Nagase, H\|Ando, H\|Yanagisawa, A\|Tsuchiya, E\|Kato, Y\|Nakamura, Y
PMID:	1423316

4.
Journal:	Nature. 1992 Sep 17;359(6392):235-7.
Title:	APC mutations occur early during colorectal tumorigenesis.
Author:	Powell, S M\|Zilz, N\|Beazer-Barclay, Y\|Bryan, T M\|Hamilton, S R\|Thibodeau, S N\|Vogelstein, B\|Kinzler, K W
PMID:	1528264

5.
Journal:	Nat Genet. 1993 Nov;5(3):279-82.
Title:	Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer.
Author:	Lindblom, A\|Tannergard, P\|Werelius, B\|Nordenskjold, M
PMID:	7903889

6.
Journal:	Cell. 1993 Nov 19;75(4):631-9.
Title:	Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse.
Author:	Dietrich, W F\|Lander, E S\|Smith, J S\|Moser, A R\|Gould, K A\|Luongo, C\|Borenstein, N\|Dove, W
PMID:	8242739

7.
Journal:	Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11109-13.
Title:	Dimer formation by an N-terminal coiled coil in the APC protein.
Author:	Joslyn, G\|Richardson, D S\|White, R\|Alber, T
PMID:	8248216

8.
Journal:	Arch Biochem Biophys. 1994 May 1;310(2):504-7.
Title:	CD44 expression in colorectal adenomas is an early event occurring prior to K-ras and p53 gene mutation.
Author:	Kim, H\|Yang, X L\|Rosada, C\|Hamilton, S R\|August, J T
PMID:	7513984

9.
Journal:	J Cancer Res Clin Oncol. 1994;120(12):727-31.
Title:	Aberrations of the APC gene in primary breast carcinoma.
Author:	Kashiwaba, M\|Tamura, G\|Ishida, M
PMID:	7798298

10.
Journal:	Mutagenesis. 1994 Sep;9(5):395-400.
Title:	Slippage--misalignment: to what extent does it contribute to mammalian cell mutagenesis?
Author:	Kimura, H\|Iyehara-Ogawa, H\|Kato, T
PMID:	7837971

11.
Journal:	Ann Hum Genet. 1994 Oct;58(4):331-42.
Title:	Age of onset in familial adenomatous polyposis: heterogeneity within families and among APC mutations.
Author:	Presciuttini, S\|Varesco, L\|Sala, P\|Gismondi, V\|Rossetti, C\|Bafico, A\|Ferrara, G B\|Bertario, L
PMID:	7864589

12.
Journal:	Rev Prat. 1994 Dec 15;44(20):2694-9.
Title:	[Genes, heredity and colorectal cancer].
Author:	Velu, T\|Ravelingien, N\|Parma, J\|Pector, J C
PMID:	7878358

13.
Journal:	Int J Cancer. 1994 Oct 1;59(1):43-7.
Title:	Mutations of the adenomatous polyposis coli gene in the mutation cluster region: comparison of human pancreatic and colorectal cancers.
Author:	Yashima, K\|Nakamori, S\|Murakami, Y\|Yamaguchi, A\|Hayashi, K\|Ishikawa, O\|Konishi, Y\|Sekiya, T
PMID:	7927902

14.
Journal:	Int J Cancer. 1994 Oct 15;59(2):248-61.
Title:	Correlation of cellular differentiation in human colorectal carcinoma and adenoma cell lines with metabolite profiles determined by 1H magnetic resonance spectroscopy.
Author:	Mackinnon, W B\|Huschtscha, L\|Dent, K\|Hancock, R\|Paraskeva, C\|Mountford, C E
PMID:	7927926

15.
Journal:	Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8969-73.
Title:	A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors.
Author:	Fodde, R\|Edelmann, W\|Yang, K\|van Leeuwen, C\|Carlson, C\|Renault, B\|Breukel, C\|Alt, E\|Lipkin, M\|Khan, P M
PMID:	8090754

16.
Journal:	Cancer Res. 1994 Jun 1;54(11):3011-20.
Title:	Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.
Author:	Miyaki, M\|Konishi, M\|Kikuchi-Yanoshita, R\|Enomoto, M\|Igari, T\|Tanaka, K\|Muraoka, M\|Takahashi, H\|Amada, Y\|Fukayama, M
PMID:	8187091

17.
Journal:	Neurology. 1994 Jun;44(6):1083-6.
Title:	Turcot's syndrome: evidence for linkage to the adenomatous polyposis coli (APC) locus.
Author:	Lasser, D M\|DeVivo, D C\|Garvin, J\|Wilhelmsen, K C
PMID:	8208405

18.
Journal:	Dev Dyn. 1995 Aug;203(4):422-33.
Title:	Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation.
Author:	Moser, A R\|Shoemaker, A R\|Connelly, C S\|Clipson, L\|Gould, K A\|Luongo, C\|Dove, W F\|Siggers, P H\|Gardner, R L
PMID:	7496034

19.
Journal:	Cancer Res. 1995 Dec 1;55(23):5504-6.
Title:	Human homologue of a candidate for the Mom1 locus, the secretory type II phospholipase A2 (PLA2S-II), maps to 1p35-36.1/D1S199.
Author:	Praml, C\|Savelyeva, L\|Le Paslier, D\|Siracusa, L D\|Buchberg, A M\|Schwab, M\|Amler, L C
PMID:	7585622

20.
Journal:	Cancer Res. 1995 Jul 15;55(14):2972-7.
Title:	APC binds to the novel protein EB1.
Author:	Su, L K\|Burrell, M\|Hill, D E\|Gyuris, J\|Brent, R\|Wiltshire, R\|Trent, J\|Vogelstein, B\|Kinzler, K W
PMID:	7606712

21.
Journal:	Genes Chromosomes Cancer. 1995 Jul;13(3):192-202.
Title:	Molecular, cytogenetic, and phenotypic studies of a constitutional reciprocal translocation t(5;10)(q22;q25) responsible for familial adenomatous polyposis in a Dutch pedigree.
Author:	van der Luijt, R B\|Tops, C M\|Khan, P M\|van der Klift, H M\|Breukel, C\|van Leeuwen-Cornelisse, I S\|Dauwerse, H G\|Beverstock, G C\|van Noort, E\|Snel, P
PMID:	7669739

22.
Journal:	Pathol Biol (Paris). 1995 Mar;43(3):159-64.
Title:	Genetic predispositions to colorectal cancer.
Author:	Thomas, G\|Olschwang, S
PMID:	7675542

23.
Journal:	Cell. 1995 Jun 16;81(6):957-66.
Title:	The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia.
Author:	MacPhee, M\|Chepenik, K P\|Liddell, R A\|Nelson, K K\|Siracusa, L D\|Buchberg, A M
PMID:	7781071

24.
Journal:	Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):910-4.
Title:	Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Author:	Kakiuchi, H\|Watanabe, M\|Ushijima, T\|Toyota, M\|Imai, K\|Weisburger, J H\|Sugimura, T\|Nagao, M
PMID:	7846077

25.
Journal:	J Cell Biochem Suppl. 1995;22:65-73.
Title:	Calcium and the prevention of colon cancer.
Author:	Lipkin, M\|Newmark, H
PMID:	8538212

26.
Journal:	Semin Surg Oncol. 1995 Nov-Dec;11(6):399-405.
Title:	Molecular biology of colon polyps and colon cancer.
Author:	Allen, J I
PMID:	8607008

27.
Journal:	J Cancer Res Clin Oncol. 1996;122(2):95-101.
Title:	Establishment and characterization of a human colon cancer cell line, OUMS-23, from a patient with familial adenomatous polyposis.
Author:	Miyazaki, M\|Tsuboi, S\|Mihara, K\|Kosaka, T\|Fukaya, K\|Kino, K\|Mori, M\|Namba, M
PMID:	8576285

28.
Journal:	J Cell Biol. 1996 Apr;133(1):199-209.
Title:	Suppression of tumorigenicity by plakoglobin: an augmenting effect of N-cadherin.
Author:	Simcha, I\|Geiger, B\|Yehuda-Levenberg, S\|Salomon, D\|Ben-Ze'ev, A
PMID:	8601608

29.
Journal:	Science. 1996 May 17;272(5264):1020-3.
Title:	Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.
Author:	Matsumine, A\|Ogai, A\|Senda, T\|Okumura, N\|Satoh, K\|Baeg, G H\|Kawahara, T\|Kobayashi, S\|Okada, M\|Toyoshima, K\|Akiyama, T
PMID:	8638125

30.
Journal:	Cancer Res. 1996 Jun 1;56(11):2556-60.
Title:	Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis.
Author:	Boolbol, S K\|Dannenberg, A J\|Chadburn, A\|Martucci, C\|Guo, X J\|Ramonetti, J T\|Abreu-Goris, M\|Newmark, H L\|Lipkin, M L\|DeCosse, J J\|Bertagnolli, M M
PMID:	8653697

31.
Journal:	Cancer Res. 1996 Jul 1;56(13):2922-6.
Title:	MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis.
Author:	Reitmair, A H\|Cai, J C\|Bjerknes, M\|Redston, M\|Cheng, H\|Pind, M T\|Hay, K\|Mitri, A\|Bapat, B V\|Mak, T W\|Gallinger, S
PMID:	8674041

32.
Journal:	J Cell Biol. 1996 Jul;134(1):165-79.
Title:	The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.
Author:	Nathke, I S\|Adams, C L\|Polakis, P\|Sellin, J H\|Nelson, W J
PMID:	8698812

33.
Journal:	Glia. 1996 Jun;17(2):169-74.
Title:	Expression of the APC tumor suppressor protein in oligodendroglia.
Author:	Bhat, R V\|Axt, K J\|Fosnaugh, J S\|Smith, K J\|Johnson, K A\|Hill, D E\|Kinzler, K W\|Baraban, J M
PMID:	8776583

34.
Journal:	Genes Chromosomes Cancer. 1996 Feb;15(2):122-8.
Title:	Germline APC mutation (Gln1317) in a cancer-prone family that does not result in familial adenomatous polyposis.
Author:	White, S\|Bubb, V J\|Wyllie, A H
PMID:	8834176

35.
Journal:	Surgery. 1996 Oct;120(4):712-7; discussion 717-8.
Title:	Introduction of human adenomatous polyposis coli gene into Min mice via cationic liposomes.
Author:	Arenas, R B\|Fichera, A\|Mok, P\|Blanco, M C\|Michelassi, F
PMID:	8862382

36.
Journal:	Scand J Gastroenterol Suppl. 1996;220:132-6.
Title:	Genetic aspects of colorectal cancer: the surgeon's view.
Author:	Sjodahl, R\|Nystrom, P O
PMID:	8898451

37.
Journal:	Genes Chromosomes Cancer. 1996 Nov;17(3):194-8.
Title:	Somatic genetic events linked to the Apc locus in intestinal adenomas of the Min mouse.
Author:	Luongo, C\|Dove, W F
PMID:	8946200

38.
Journal:	Proc Natl Acad Sci U S A. 1997 Jan 7;94(1):242-7.
Title:	A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo.
Author:	Hayashi, S\|Rubinfeld, B\|Souza, B\|Polakis, P\|Wieschaus, E\|Levine, A J
PMID:	8990193

39.
Journal:	Cancer Res. 1997 Jan 15;57(2):199-201.
Title:	Ornithine decarboxylase and polyamines in familial adenomatous polyposis.
Author:	Giardiello, F M\|Hamilton, S R\|Hylind, L M\|Yang, V W\|Tamez, P\|Casero, R A Jr
PMID:	9000553

40.
Journal:	Int J Cancer. 1997 Jul 3;72(1):197-202.
Title:	Expression of transgenic carcinoembryonic antigen (CEA) in tumor-prone mice: an animal model for CEA-directed tumor immunotherapy.
Author:	Thompson, J A\|Eades-Perner, A M\|Ditter, M\|Muller, W J\|Zimmermann, W
PMID:	9212243

41.
Journal:	Tidsskr Nor Laegeforen. 1997 May 30;117(14):2046-51.
Title:	[Genetic and environmental factors in colorectal cancer. Mutations in the familial adenomatous polyposis gene].
Author:	Steffensen, I L\|Paulsen, J E\|Alexander, J
PMID:	9235686

42.
Journal:	Z Arztl Fortbild Qualitatssich. 1997 Mar;91(2):125-33.
Title:	[Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy].
Author:	Jacobasch, G\|Jacobasch, K H
PMID:	9244653

43.
Journal:	J Biol Chem. 1997 Aug 29;272(35):21681-4.
Title:	Phosphorylation of the tumor suppressor adenomatous polyposis coli (APC) by the cyclin-dependent kinase p34.
Author:	Trzepacz, C\|Lowy, A M\|Kordich, J J\|Groden, J
PMID:	9268294

44.
Journal:	Gan To Kagaku Ryoho. 1997 Sep;24(11):1432-5.
Title:	[APC, beta-catenin, DLG].
Author:	Akiyama, T
PMID:	9309137

45.
Journal:	Carcinogenesis. 1997 Oct;18(10):1863-5.
Title:	Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice.
Author:	Hioki, K\|Shivapurkar, N\|Oshima, H\|Alabaster, O\|Oshima, M\|Taketo, M M
PMID:	9363991

46.
Journal:	Cancer Res. 1997 Dec 15;57(24):5480-4.
Title:	The I1307K APC mutation does not predispose to colorectal cancer in Jewish Ashkenazi breast and breast-ovarian cancer kindreds.
Author:	Petrukhin, L\|Dangel, J\|Vanderveer, L\|Costalas, J\|Bellacosa, A\|Grana, G\|Daly, M\|Godwin, A K
PMID:	9407954

47.
Journal:	Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300.
Title:	Molecular biology of colorectal cancer.
Author:	Gryfe, R\|Swallow, C\|Bapat, B\|Redston, M\|Gallinger, S\|Couture, J
PMID:	9438104

48.
Journal:	Carcinogenesis. 1997 Dec;18(12):2435-9.
Title:	AOM-induced mouse colon tumors do not express full-length APC protein.
Author:	Maltzman, T\|Whittington, J\|Driggers, L\|Stephens, J\|Ahnen, D
PMID:	9450492

49.
Journal:	Mutat Res. 1997 Dec 12;395(2-3):93-9.
Title:	Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene.
Author:	Okonogi, H\|Stuart, G R\|Okochi, E\|Ushijima, T\|Sugimura, T\|Glickman, B W\|Nagao, M
PMID:	9465918

50.
Journal:	Mol Pathol. 1997 Dec;50(6):289-90.
Title:	Cadherin and catenin biology represent a global mechanism for epithelial cancer progression.
Author:	Jankowski, J A\|Bruton, R\|Shepherd, N\|Sanders, D S
PMID:	9536277

51.
Journal:	Bull Cancer. 1997 Nov;84(11):1053-60.
Title:	[Current data on the role of APC protein in the origin of colorectal cancer].
Author:	Bonneton, C\|Larue, L\|Thiery, J P
PMID:	9536987

52.
Journal:	J Cell Biochem Suppl. 1997;28-29:144-7.
Title:	New rodent models for studies of chemopreventive agents.
Author:	Lipkin, M
PMID:	9589360

53.
Journal:	J Chir (Paris). 1997 Dec;134(7-8):279-82.
Title:	[The application of molecular technics in the management of colorectal cancer].
Author:	Laurent-Puig, P\|Cugnenc, P H
PMID:	9772989

54.
Journal:	Nucleic Acids Res. 1998 Jan 1;26(1):269-70.
Title:	APC gene: database of germline and somatic mutations in human tumors and cell lines.
Author:	Laurent-Puig, P\|Beroud, C\|Soussi, T
PMID:	9399850

55.
Journal:	Gan To Kagaku Ryoho. 1998 Feb;25(3):419-22.
Title:	[A case of hepatic metastasis of rectal cancer with familial adenomatous polyposis treated by transarterial administration of low-dose leucovorin and 5-FU].
Author:	Ishii, Y\|Wakayama, H\|Nakayama, K\|Ami, K\|Iida, M\|Hotta, M\|Oota, K\|Yamazaki, S\|Takahashi, M
PMID:	9492838

56.
Journal:	Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3122-7.
Title:	Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells.
Author:	Efstathiou, J A\|Noda, M\|Rowan, A\|Dixon, C\|Chinery, R\|Jawhari, A\|Hattori, T\|Wright, N A\|Bodmer, W F\|Pignatelli, M
PMID:	9501226

57.
Journal:	Cancer Res. 1998 Mar 15;58(6):1087-9.
Title:	Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice.
Author:	Baker, S M\|Harris, A C\|Tsao, J L\|Flath, T J\|Bronner, C E\|Gordon, M\|Shibata, D\|Liskay, R M
PMID:	9515784

58.
Journal:	Cancer Res. 1998 Mar 15;58(6):1127-9.
Title:	High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat.
Author:	Dashwood, R H\|Suzui, M\|Nakagama, H\|Sugimura, T\|Nagao, M
PMID:	9515794

59.
Journal:	Ann Surg Oncol. 1998 Mar;5(2):181-5.
Title:	Absence of frequent involvement of modifier of Min(APC) in sporadic colorectal cancer.
Author:	Kahlenberg, M S\|Stoler, D L\|Petrelli, N J\|Rodriguez-Bigas, M\|Weber, T K\|Anderson, G R
PMID:	9527272

60.
Journal:	Genes Chromosomes Cancer. 1998 May;22(1):37-41.
Title:	A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients.
Author:	Muller, O\|Nimmrich, I\|Finke, U\|Friedl, W\|Hoffmann, I
PMID:	9591632

61.
Journal:	Carcinogenesis. 1998 Apr;19(4):543-9.
Title:	Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas.
Author:	Sheng, H\|Shao, J\|Williams, C S\|Pereira, M A\|Taketo, M M\|Oshima, M\|Reynolds, A B\|Washington, M K\|DuBois, R N\|Beauchamp, R D
PMID:	9600336

62.
Journal:	Hum Mutat. 1998;11(6):450-5.
Title:	A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9.
Author:	Young, J\|Simms, L A\|Tarish, J\|Buttenshaw, R\|Knight, N\|Anderson, G J\|Bell, A\|Leggett, B
PMID:	9603437

63.
Journal:	Jpn J Clin Oncol. 1998 Mar;28(3):163-7.
Title:	Experimental chemical carcinogenesis in the stomach and colon.
Author:	Sugimura, T\|Terada, M
PMID:	9614437

64.
Journal:	Br J Cancer. 1998 Jun;77(12):2148-51.
Title:	Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
Author:	De Filippo, C\|Caderni, G\|Bazzicalupo, M\|Briani, C\|Giannini, A\|Fazi, M\|Dolara, P
PMID:	9649126

65.
Journal:	Curr Biol. 1998 Jul 2;8(14):823-30.
Title:	Sequence-based design of a peptide probe for the APC tumor suppressor protein.
Author:	Sharma, V A\|Logan, J\|King, D S\|White, R\|Alber, T
PMID:	9663391

66.
Journal:	J Pathol. 1998 Apr;184(4):390-5.
Title:	Mutation of the transforming growth factor-beta type II receptor gene in right-sided colorectal cancer: relationship to clinicopathological features and genetic alterations.
Author:	Iacopetta, B J\|Welch, J\|Soong, R\|House, A K\|Zhou, X P\|Hamelin, R
PMID:	9664904

67.
Journal:	Philos Trans R Soc Lond B Biol Sci. 1998 Jun 29;353(1370):915-23.
Title:	The intestinal epithelium and its neoplasms: genetic, cellular and tissue interactions.
Author:	Dove, W F\|Cormier, R T\|Gould, K A\|Halberg, R B\|Merritt, A J\|Newton, M A\|Shoemaker, A R
PMID:	9684289

68.
Journal:	Surgery. 1998 Aug;124(2):225-31.
Title:	Aspirin prevents tumors in a murine model of familial adenomatous polyposis.
Author:	Mahmoud, N N\|Dannenberg, A J\|Mestre, J\|Bilinski, R T\|Churchill, M R\|Martucci, C\|Newmark, H\|Bertagnolli, M M
PMID:	9706142

69.
Journal:	Science. 1998 Sep 4;281(5382):1509-12.
Title:	Identification of c-MYC as a target of the APC pathway.
Author:	He, T C\|Sparks, A B\|Rago, C\|Hermeking, H\|Zawel, L\|da Costa, L T\|Morin, P J\|Vogelstein, B\|Kinzler, K W
PMID:	9727977

70.
Journal:	J Gastroenterol. 1998 Oct;33(5):618-24.
Title:	Roles of COX-1 and COX-2 in gastrointestinal pathophysiology.
Author:	Sakamoto, C
PMID:	9773924

71.
Journal:	Teratog Carcinog Mutagen. 1998;18(4):183-97.
Title:	Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.
Author:	Davies, M J\|Rumsby, P C
PMID:	9804274

72.
Journal:	Cancer Res. 1998 Dec 15;58(24):5713-7.
Title:	Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis.
Author:	Yang, K\|Edelmann, W\|Fan, K\|Lau, K\|Leung, D\|Newmark, H\|Kucherlapati, R\|Lipkin, M
PMID:	9865728

73.
Journal:	Am J Hum Genet. 1999 Feb;64(2):378-84.
Title:	Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism.
Author:	Gryfe, R\|Di Nicola, N\|Lal, G\|Gallinger, S\|Redston, M
PMID:	9973276

74.
Journal:	Curr Biol. 1999 Jan 28;9(2):105-8.
Title:	Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor.
Author:	van Es, J H\|Kirkpatrick, C\|van de Wetering, M\|Molenaar, M\|Miles, A\|Kuipers, J\|Destree, O\|Peifer, M\|Clevers, H
PMID:	10021369

75.
Journal:	Br J Cancer. 1999 Mar;79(9-10):1399-405.
Title:	Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.
Author:	Hull, M A\|Booth, J K\|Tisbury, A\|Scott, N\|Bonifer, C\|Markham, A F\|Coletta, P L
PMID:	10188882

76.
Journal:	Mol Carcinog. 1999 Mar;24(3):232-7.
Title:	Frequent mutations of the rat beta-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone.
Author:	Suzui, M\|Ushijima, T\|Dashwood, R H\|Yoshimi, N\|Sugimura, T\|Mori, H\|Nagao, M
PMID:	10204808

77.
Journal:	Clin Cancer Res. 1999 Apr;5(4):855-63.
Title:	Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse.
Author:	Ritland, S R\|Leighton, J A\|Hirsch, R E\|Morrow, J D\|Weaver, A L\|Gendler, S J
PMID:	10213222

78.
Journal:	Anticancer Res. 1999 Jan-Feb;19(1A):601-4.
Title:	Exon 14-skipping of the adenomatous polyposis coli gene in purified epithelial cells of colonic mucosa and tumors.
Author:	Sulekova, Z\|Reymond, M\|Kockerling, F\|Hohenberger, W\|Ballhausen, W G
PMID:	10226605

79.
Journal:	Genes Dev. 1999 May 15;13(10):1309-21.
Title:	Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development.
Author:	Smits, R\|Kielman, M F\|Breukel, C\|Zurcher, C\|Neufeld, K\|Jagmohan-Changur, S\|Hofland, N\|van Dijk, J\|White, R\|Edelmann, W\|Kucherlapati, R\|Khan, P M\|Fodde, R
PMID:	10346819

80.
Journal:	J Cancer Res Clin Oncol. 1999;125(5):297-304.
Title:	Intracellular distribution of beta-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps.
Author:	Herter, P\|Kuhnen, C\|Muller, K M\|Wittinghofer, A\|Muller, O
PMID:	10359135

81.
Journal:	Neuroscience. 1999;91(2):661-72.
Title:	Neuronal localization of the Adenomatous polyposis coli tumor suppressor protein.
Author:	Brakeman, J S\|Gu, S H\|Wang, X B\|Dolin, G\|Baraban, J M
PMID:	10366023

82.
Journal:	Cancer Res. 1999 Jun 15;59(12):2759-65.
Title:	Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay.
Author:	Bieche, I\|Laurendeau, I\|Tozlu, S\|Olivi, M\|Vidaud, D\|Lidereau, R\|Vidaud, M
PMID:	10383126

83.
Journal:	Cancer. 1999 Jul 1;86(1):31-6.
Title:	K-ras mutation and loss of heterozygosity of the adenomatous polyposis coli gene in patients with colorectal adenomas with in situ carcinoma.
Author:	Zauber, N P\|Sabbath-Solitare, M\|Marotta, S P\|Bishop, D T
PMID:	10391560

84.
Journal:	Cell Growth Differ. 1999 Jun;10(6):369-76.
Title:	Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer.
Author:	Caca, K\|Kolligs, F T\|Ji, X\|Hayes, M\|Qian, J\|Yahanda, A\|Rimm, D L\|Costa, J\|Fearon, E R
PMID:	10392898

85.
Journal:	Genes Chromosomes Cancer. 1999 Aug;25(4):396-8.
Title:	Germline mutations are frequent in the APC gene but absent in the beta-catenin gene in familial adenomatous polyposis patients.
Author:	Cao, X\|Eu, K W\|Seow-Choen, F\|Cheah, P Y
PMID:	10398435

86.
Journal:	Int J Cancer. 1999 Aug 20;84(4):404-9.
Title:	Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma.
Author:	Ko, J M\|Cheung, M H\|Kwan, M W\|Wong, C M\|Lau, K W\|Tang, C M\|Lung, M L
PMID:	10404094

87.
Journal:	Diagn Mol Pathol. 1999 Mar;8(1):11-9.
Title:	Optimizing the APC gene mutation analysis in archival colorectal tumor tissue.
Author:	Poncin, J\|Mulkens, J\|Arends, J W\|de Goeij, A
PMID:	10408788

88.
Journal:	Gan To Kagaku Ryoho. 1999 May;26(6):735-43.
Title:	[Familial cancer: recent advances].
Author:	Baba, S
PMID:	10410140

89.
Journal:	Histopathology. 1999 Sep;35(3):249-56.
Title:	Reduced expression of APC and DCC gene protein in breast cancer.
Author:	Ho, K Y\|Kalle, W H\|Lo, T H\|Lam, W Y\|Tang, C M
PMID:	10469217

90.
Journal:	Genes Cells. 1999 Aug;4(8):465-74.
Title:	Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC.
Author:	Hamada, F\|Murata, Y\|Nishida, A\|Fujita, F\|Tomoyasu, Y\|Nakamura, M\|Toyoshima, K\|Tabata, T\|Ueno, N\|Akiyama, T
PMID:	10526234

91.
Journal:	Carcinogenesis. 1999 Nov;20(11):2045-9.
Title:	Introduction of full-length APC modulates cyclooxygenase-2 expression in HT-29 human colorectal carcinoma cells at the translational level.
Author:	Hsi, L C\|Angerman-Stewart, J\|Eling, T E
PMID:	10545404

92.
Journal:	Cytogenet Cell Genet. 1999;86(2):105-11.
Title:	Mechanisms of APC-driven tumorigenesis: lessons from mouse models.
Author:	Fodde, R\|Smits, R\|Hofland, N\|Kielman, M\|Meera Khan, P
PMID:	10545699

93.
Journal:	Carcinogenesis. 1999 Dec;20(12):2345-50.
Title:	The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer.
Author:	Sohn, K J\|Puchyr, M\|Salomon, R N\|Graeme-Cook, F\|Fung, L\|Choi, S W\|Mason, J B\|Medline, A\|Kim, Y I
PMID:	10590231

94.
Journal:	Int J Colorectal Dis. 1999 Dec;14(6):277-81.
Title:	Preliminary report on pathology of colorectal cancer in Poland in 1995 and 1975: is it still the same disease?
Author:	Rudzki, Z\|Stachura, J
PMID:	10663894

95.
Journal:	Ann N Y Acad Sci. 1999;889:32-44.
Title:	APC and intestinal carcinogenesis. Insights from animal models.
Author:	Bertagnolli, M M
PMID:	10668480

96.
Journal:	Gen Physiol Biophys. 1999 Sep;18(3):311-6.
Title:	Are intestinal tumours in Apc+/-mice a suitable model of colorectal carcinoma in man?
Author:	Lojda, Z\|Havrankova, E\|Sovova, V\|Sloncova, E\|Fric, P
PMID:	10703747

97.
Journal:	Verh Dtsch Ges Pathol. 1999;83:139-47.
Title:	[Are there differences between ex adenoma and de novo colorectal carcinomas?].
Author:	Mueller, J\|Mueller, E\|Keller, G\|Bethke, B\|Stolte, M\|Hofler, H
PMID:	10714204

98.
Journal:	Eur J Cancer Prev. 1999 Dec;8 Suppl 1:S87-94.
Title:	Carcinogenesis in the colon: interaction between luminal factors and genetic factors.
Author:	Glinghammar, B\|Rafter, J
PMID:	10772422

99.
Journal:	J Dermatol Sci. 2000 Feb;22(2):102-6.
Title:	Loss of heterozygosity of adenomatous polyposis coli gene in cutaneous tumors as determined by using polymerase chain reaction and paraffin section preparations.
Author:	Ichihashi, N\|Kitajima, Y
PMID:	10674823

100.
Journal:	Cancer Res. 2000 Feb 15;60(4):1070-6.
Title:	Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice.
Author:	Hassan, A B\|Howell, J A
PMID:	10706126

101.
Journal:	Eur J Hum Genet. 2000 Jan;8(1):42-8.
Title:	APC mutation and phenotypic spectrum of Singapore familial adenomatous polyposis patients.
Author:	Cao, X\|Eu, K W\|Seow-Choen, F\|Zao, Y\|Cheah, P Y
PMID:	10713886

102.
Journal:	Toxicol Lett. 2000 Mar 15;112-113:403-9.
Title:	Modulation by dietary factors in murine FAP models.
Author:	Paulsen, J E
PMID:	10720759

103.
Journal:	Cancer Res. 2000 Apr 1;60(7):1864-70.
Title:	Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos.
Author:	Jacoby, R F\|Cole, C E\|Tutsch, K\|Newton, M A\|Kelloff, G\|Hawk, E T\|Lubet, R A
PMID:	10766173

104.
Journal:	Jpn J Clin Oncol. 2000 Feb;30(2):82-8.
Title:	The relationship between frequencies of extracolonic manifestations and the position of APC germline mutation in patients with familial adenomatous polyposis.
Author:	Enomoto, M\|Konishi, M\|Iwama, T\|Utsunomiya, J\|Sugihara, K I\|Miyaki, M
PMID:	10768871

105.
Journal:	Carcinogenesis. 2000 May;21(5):921-7.
Title:	Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.
Author:	Mahmoud, N N\|Carothers, A M\|Grunberger, D\|Bilinski, R T\|Churchill, M R\|Martucci, C\|Newmark, H L\|Bertagnolli, M M
PMID:	10783313

106.
Journal:	Carcinogenesis. 2000 May;21(5):953-8.
Title:	Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522.
Author:	Sasai, H\|Masaki, M\|Wakitani, K
PMID:	10783317

107.
Journal:	Oncogene. 2000 May 25;19(23):2774-9.
Title:	Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice.
Author:	Shoemaker, A R\|Haigis, K M\|Baker, S M\|Dudley, S\|Liskay, R M\|Dove, W F
PMID:	10851078

108.
Journal:	Cancer Res. 2000 Jun 15;60(12):3191-9.
Title:	Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice.
Author:	Song, J\|Sohn, K J\|Medline, A\|Ash, C\|Gallinger, S\|Kim, Y I
PMID:	10866310

109.
Journal:	Gastroenterology. 2000 Jul;119(1):151-61.
Title:	Effects of dietary folate on DNA strand breaks within mutation-prone exons of the p53 gene in rat colon.
Author:	Kim, Y I\|Shirwadkar, S\|Choi, S W\|Puchyr, M\|Wang, Y\|Mason, J B
PMID:	10889164

110.
Journal:	Ann N Y Acad Sci. 2000 Jun;910:36-47; discussion 47-9.
Title:	Genetic testing for familial adenomatous polyposis.
Author:	Ballhausen, W G
PMID:	10911904

111.
Journal:	Science. 2000 Aug 18;289(5482):1194-7.
Title:	Asef, a link between the tumor suppressor APC and G-protein signaling.
Author:	Kawasaki, Y\|Senda, T\|Ishidate, T\|Koyama, R\|Morishita, T\|Iwayama, Y\|Higuchi, O\|Akiyama, T
PMID:	10947987

112.
Journal:	Oncogene. 2000 Aug 10;19(34):3894-901.
Title:	The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain.
Author:	Erdmann, K S\|Kuhlmann, J\|Lessmann, V\|Herrmann, L\|Eulenburg, V\|Muller, O\|Heumann, R
PMID:	10951583

113.
Journal:	Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12085-90.
Title:	Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm.
Author:	Neufeld, K L\|Nix, D A\|Bogerd, H\|Kang, Y\|Beckerle, M C\|Cullen, B R\|White, R L
PMID:	11035805

114.
Journal:	Mod Pathol. 2000 Oct;13(10):1055-9.
Title:	Mutations in beta-catenin and APC genes are uncommon in esophageal and esophagogastric junction adenocarcinomas.
Author:	Choi, Y W\|Heath, E I\|Heitmiller, R\|Forastiere, A A\|Wu, T T
PMID:	11048797

115.
Journal:	Carcinogenesis. 2000 Nov;21(11):1935-40.
Title:	Expression of beta-catenin and full-length APC protein in normal and neoplastic colonic tissues.
Author:	Iwamoto, M\|Ahnen, D J\|Franklin, W A\|Maltzman, T H
PMID:	11062151

116.
Journal:	Mol Med Today. 2000 Dec;6(12):462-9.
Title:	The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.
Author:	Sieber, O M\|Tomlinson, I P\|Lamlum, H
PMID:	11099951

117.
Journal:	Neoplasma. 2000;47(6):335-41.
Title:	A double germline mutations in the APC and p53 genes.
Author:	Zajac, V\|Tomka, M\|Ilencikova, D\|Majek, P\|Stevurkova, V\|Kirchhoff, T
PMID:	11263856

118.
Journal:	Oncol Res. 2000;12(4):193-201.
Title:	Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3beta activity and increases levels of both membrane-bound and Apc/axin/GSK-3beta complex-associated pools of beta-catenin.
Author:	Vincan, E\|Leet, C S\|Reyes, N I\|Dilley, R J\|Thomas, R J\|Phillips, W A
PMID:	11341469

119.
Journal:	Colorectal Dis. 2000 Sep;2(5):304-8.
Title:	Evaluation of colonoscopic sized biopsies for microsatellite instability and adenomatous polyposis coli (APC) variants.
Author:	Sengupta\|Pearson\|Yiu\|Boulos
PMID:	23578122

120.
Journal:	Gastroenterology. 2001 Feb;120(2):392-400.
Title:	APC I1307K increases risk of transition from polyp to colorectal carcinoma in Ashkenazi Jews.
Author:	Stern, H S\|Viertelhausen, S\|Hunter, A G\|O'Rourke, K\|Cappelli, M\|Perras, H\|Serfas, K\|Blumenthall, A\|Dewar, D\|Baumann, E\|Lagarde, A E
PMID:	11159880

121.
Journal:	Curr Biol. 2001 Jan 9;11(1):44-9.
Title:	Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation.
Author:	Zumbrunn, J\|Kinoshita, K\|Hyman, A A\|Nathke, I S
PMID:	11166179

122.
Journal:	Carcinogenesis. 2001 Feb;22(2):329-35.
Title:	Early detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.
Author:	Burnouf, D\|Miturski, R\|Nagao, M\|Nakagama, H\|Nothisen, M\|Wagner, J\|Fuchs, R P
PMID:	11181456

123.
Journal:	Mod Pathol. 2001 Jan;14(1):29-39.
Title:	Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers.
Author:	Aust, D E\|Terdiman, J P\|Willenbucher, R F\|Chew, K\|Ferrell, L\|Florendo, C\|Molinaro-Clark, A\|Baretton, G B\|Lohrs, U\|Waldman, F M
PMID:	11211307

124.
Journal:	Cancer Res. 2001 Jan 15;61(2):565-9.
Title:	Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal.
Author:	Yang, W C\|Mathew, J\|Velcich, A\|Edelmann, W\|Kucherlapati, R\|Lipkin, M\|Yang, K\|Augenlicht, L H
PMID:	11212250

125.
Journal:	Oncogene. 2001 Jan 4;20(1):133-40.
Title:	Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells.
Author:	Tan, C\|Costello, P\|Sanghera, J\|Dominguez, D\|Baulida, J\|de Herreros, A G\|Dedhar, S
PMID:	11244511

126.
Journal:	Cancer Res. 2001 Feb 15;61(4):1733-40.
Title:	Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.
Author:	Oshima, M\|Murai, N\|Kargman, S\|Arguello, M\|Luk, P\|Kwong, E\|Taketo, M M\|Evans, J F
PMID:	11245490

127.
Journal:	Eur J Cancer. 2001 Mar;37(4):499-502.
Title:	APC I1307K and E1317Q variants are rare or do not occur in Swedish colorectal cancer patients.
Author:	Evertsson, S\|Lindblom, A\|Sun, X F
PMID:	11267860

128.
Journal:	Cancer Detect Prev. 2001;25(1):55-61.
Title:	Detection of APC and k-ras mutations in the serum of patients with colorectal cancer.
Author:	Lauschke, H\|Caspari, R\|Friedl, W\|Schwarz, B\|Mathiak, M\|Propping, P\|Hirner, A
PMID:	11270422

129.
Journal:	J Biol Chem. 2001 Jun 8;276(23):20108-15. Epub 2001 Mar 26.
Title:	PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.
Author:	Howe, L R\|Crawford, H C\|Subbaramaiah, K\|Hassell, J A\|Dannenberg, A J\|Brown, A M
PMID:	11274170

130.
Journal:	Nat Cell Biol. 2001 Apr;3(4):429-32.
Title:	A role for the Adenomatous Polyposis Coli protein in chromosome segregation.
Author:	Kaplan, K B\|Burds, A A\|Swedlow, J R\|Bekir, S S\|Sorger, P K\|Nathke, I S
PMID:	11283619

131.
Journal:	Nat Cell Biol. 2001 Apr;3(4):433-8.
Title:	Mutations in the APC tumour suppressor gene cause chromosomal instability.
Author:	Fodde, R\|Kuipers, J\|Rosenberg, C\|Smits, R\|Kielman, M\|Gaspar, C\|van Es, J H\|Breukel, C\|Wiegant, J\|Giles, R H\|Clevers, H
PMID:	11283620

132.
Journal:	Carcinogenesis. 2001 Apr;22(4):665-71.
Title:	Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development.
Author:	Sturlan, S\|Oberhuber, G\|Beinhauer, B G\|Tichy, B\|Kappel, S\|Wang, J\|Rogy, M A
PMID:	11285204

133.
Journal:	Hum Mutat. 2001 May;17(5):434-5.
Title:	Nine novel APC mutations in Italian FAP patients.
Author:	Resta, N\|Stella, A\|Susca, F\|Montera, M\|Gentile, M\|Cariola, F\|Prete, F\|Tenconi, R\|Tibiletti, M G\|Logrieco, G\|Mattina, T\|Andriulli, G\|Caruso, M L\|Fiorente, P\|Russo, S\|Caputi-Jambrenghi, O\|Mareni, C\|Guanti, G
PMID:	11317365

134.
Journal:	Int J Colorectal Dis. 2001 Apr;16(2):102-7.
Title:	Mutations at the APC exon 15 in the colorectal neoplastic tissues of serial array.
Author:	Kim, J C\|Koo, K H\|Lee, D H\|Roh, S A\|Kim, H C\|Yu, C S\|Kang, G H
PMID:	11355315

135.
Journal:	Langenbecks Arch Surg. 2001 Apr;386(3):163-71.
Title:	Carcinogenesis of cancer of the papilla and ampulla: pathophysiological facts and molecular biological mechanisms.
Author:	Esposito, I\|Friess, H\|Buchler, M W
PMID:	11382316

136.
Journal:	Z Gastroenterol. 2001 May;39(5):365-7.
Title:	[Colorectal carcinoma in Cronkhite-Canada syndrome].
Author:	Zugel, N P\|Hehl, J A\|Jechart, G\|Tannapfel, A\|Wienbeck, M\|Witte, J
PMID:	11413916

137.
Journal:	Br J Cancer. 2001 Jul 6;85(1):69-73.
Title:	Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers.
Author:	Jin, Z\|Tamura, G\|Tsuchiya, T\|Sakata, K\|Kashiwaba, M\|Osakabe, M\|Motoyama, T
PMID:	11437404

138.
Journal:	Cancer Genet Cytogenet. 2001 Jul 1;128(1):43-5.
Title:	Beta-catenin activation through mutation is rare in rectal cancer.
Author:	Nilbert, M\|Rambech, E
PMID:	11454429

139.
Journal:	Cancer Res. 2001 Aug 15;61(16):6131-6.
Title:	Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor.
Author:	Lal, G\|Ash, C\|Hay, K\|Redston, M\|Kwong, E\|Hancock, B\|Mak, T\|Kargman, S\|Evans, J F\|Gallinger, S
PMID:	11507063

140.
Journal:	Oncogene. 2001 Aug 9;20(35):4884-90.
Title:	Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.
Author:	Dang, D T\|Mahatan, C S\|Dang, L H\|Agboola, I A\|Yang, V W
PMID:	11521200

141.
Journal:	Cancer Res. 2001 Oct 1;61(19):7060-4.
Title:	Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in Apc(Min/+) and Apc(Min/+), Msh2(-/-) mice.
Author:	Sansom, O J\|Stark, L A\|Dunlop, M G\|Clarke, A R
PMID:	11585736

142.
Journal:	J Biol Chem. 2001 Dec 7;276(49):45833-9. Epub 2001 Oct 3.
Title:	ARM domain-dependent nuclear import of adenomatous polyposis coli protein is stimulated by the B56 alpha subunit of protein phosphatase 2A.
Author:	Galea, M A\|Eleftheriou, A\|Henderson, B R
PMID:	11585828

143.
Journal:	Nutr Cancer. 2001;39(1):102-7.
Title:	Resveratrol inhibits intestinal tumorigenesis and modulates host-defense-related gene expression in an animal model of human familial adenomatous polyposis.
Author:	Schneider, Y\|Duranton, B\|Gosse, F\|Schleiffer, R\|Seiler, N\|Raul, F
PMID:	11588890

144.
Journal:	Hum Mutat. 2001 Oct;18(4):355.
Title:	Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer.
Author:	Ruiz-Ponte, C\|Vega, A\|Carracedo, A\|Barros, F
PMID:	11668620

145.
Journal:	Oncogene. 2001 Oct 18;20(47):6871-80.
Title:	Studies on human colon cancer gene APC by targeted expression in Drosophila.
Author:	Bhandari, P\|Shashidhara, L S
PMID:	11687966

146.
Journal:	Hum Mol Genet. 2001 Dec 15;10(26):3001-7.
Title:	DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Author:	Esteller, M\|Fraga, M F\|Guo, M\|Garcia-Foncillas, J\|Hedenfalk, I\|Godwin, A K\|Trojan, J\|Vaurs-Barriere, C\|Bignon, Y J\|Ramus, S\|Benitez, J\|Caldes, T\|Akiyama, Y\|Yuasa, Y\|Launonen, V\|Canal, M J\|Rodriguez, R\|Capella, G\|Peinado, M A\|Borg, A\|Aaltonen, L A\|Ponder,
PMID:	11751682

147.
Journal:	Nat Rev Cancer. 2001 Oct;1(1):55-67.
Title:	APC, signal transduction and genetic instability in colorectal cancer.
Author:	Fodde, R\|Smits, R\|Clevers, H
PMID:	11900252

148.
Journal:	Carcinogenesis. 2002 Jan;23(1):197-200.
Title:	Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet.
Author:	Ubagai, Tsuneyuki\|Ochiai, Masako\|Kawamori, Toshihiko\|Imai, Hiroshi\|Sugimura, Takashi\|Nagao, Minako\|Nakagama, Hitoshi
PMID:	11756241

149.
Journal:	Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):297-302.
Title:	Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene.
Author:	Hasegawa, Sumitaka\|Sato, Tomoyuki\|Akazawa, Hiroshi\|Okada, Hitoshi\|Maeno, Akiteru\|Ito, Masaki\|Sugitani, Yoshinobu\|Shibata, Hiroyuki\|Miyazaki Ji, Jun-ichi\|Katsuki, Motoya\|Yamauchi, Yasutaka\|Yamamura Ki, Ken-ichi\|Katamine, Shigeru\|Noda, Tetsuo
PMID:	11756652

150.
Journal:	Nat Genet. 2002 Feb;30(2):227-32. Epub 2002 Jan 30.
Title:	Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
Author:	Al-Tassan, Nada\|Chmiel, Nikolas H\|Maynard, Julie\|Fleming, Nick\|Livingston, Alison L\|Williams, Geraint T\|Hodges, Angela K\|Davies, D Rhodri\|David, Sheila S\|Sampson, Julian R\|Cheadle, Jeremy P
PMID:	11818965

151.
Journal:	Development. 2002 Apr;129(7):1751-62.
Title:	Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development.
Author:	Ahmed, Yashi\|Nouri, Ali\|Wieschaus, Eric
PMID:	11923210

152.
Journal:	Eur J Cancer. 2002 May;38(7):867-71.
Title:	The APC gene in colorectal cancer.
Author:	Fodde, R
PMID:	11978510

153.
Journal:	Nat Rev Mol Cell Biol. 2002 May;3(5):328-38.
Title:	The subcellular destinations of APC proteins.
Author:	Bienz, Mariann
PMID:	11988767

154.
Journal:	Gut. 2002 Jun;50(6):845-50.
Title:	Genetic and clinical characterisation of familial adenomatous polyposis: a population based study.
Author:	Moisio, A-L\|Jarvinen, H\|Peltomaki, P
PMID:	12010888

155.
Journal:	Cancer Res. 2002 Jun 1;62(11):3271-5.
Title:	The DNA polymerase beta replication error spectrum in the adenomatous polyposis coli gene contains human colon tumor mutational hotspots.
Author:	Muniappan, Brindha P\|Thilly, William G
PMID:	12036944

156.
Journal:	Cancer Lett. 2002 Sep 8;183(1):31-41.
Title:	Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.
Author:	Suzui, Masumi\|Okuno, Masataka\|Tanaka, Takuji\|Nakagama, Hitoshi\|Moriwaki, Hisataka
PMID:	12049812

157.
Journal:	Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8927-31.
Title:	Intestinal adenomas can develop with a stable karyotype and stable microsatellites.
Author:	Haigis, Kevin M\|Caya, James G\|Reichelderfer, Mark\|Dove, William F
PMID:	12060718

158.
Journal:	Dis Colon Rectum. 2002 Jul;45(7):887-9.
Title:	Teenagers with familial adenomatous polyposis: what is their risk for colorectal cancer?
Author:	Church, James M\|McGannon, Ellen\|Burke, Carol\|Clark, Brian
PMID:	12130875

159.
Journal:	Am J Gastroenterol. 2002 Jul;97(7):1822-7.
Title:	Challenge in the differentiation between attenuated familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer: case report with review of the literature.
Author:	Cao, Yangming\|Pieretti, Maura\|Marshall, Jay\|Khattar, Nada H\|Chen, Bifen\|Kam-Morgan, Lauren\|Lynch, Henry
PMID:	12135043

160.
Journal:	Gastroenterology. 2002 Aug;123(2):492-504.
Title:	Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice.
Author:	Janssen, Klaus-Peter\|el-Marjou, Fatima\|Pinto, Daniel\|Sastre, Xavier\|Rouillard, Dany\|Fouquet, Coralie\|Soussi, Thierry\|Louvard, Daniel\|Robine, Sylvie
PMID:	12145803

161.
Journal:	Bull Acad Natl Med. 2002;186(2):421-43; discussion 443-5.
Title:	[Recent notions on intestinal cancerogenesis, their implications in genetic risk screening and preventive action of non-steroid anti-inflammatory agents].
Author:	Couturier, Daniel
PMID:	12145848

162.
Journal:	Ned Tijdschr Geneeskd. 2002 Jul 20;146(29):1355-9.
Title:	[Desmoid tumors in patients with familial adenomatous polyposis].
Author:	Pikaar, A\|Nortier, J W R\|Griffioen, G\|Vasen, H F A
PMID:	12162172

163.
Journal:	Cancer Res. 2002 Aug 15;62(16):4558-61.
Title:	No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice.
Author:	Takaku, Kazuaki\|Wrana, Jeffrey L\|Robertson, Elizabeth J\|Taketo, Makoto M
PMID:	12183405

164.
Journal:	Gastroenterology. 2002 Sep;123(3):751-63.
Title:	The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway.
Author:	Heinen, Christopher D\|Goss, Kathleen Heppner\|Cornelius, James R\|Babcock, George F\|Knudsen, Erik S\|Kowalik, Timothy\|Groden, Joanna
PMID:	12198702

165.
Journal:	Dev Biol. 2002 Oct 1;250(1):71-90.
Title:	Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations.
Author:	Akong, Kathryn\|McCartney, Brooke M\|Peifer, Mark
PMID:	12297097

166.
Journal:	Dev Biol. 2002 Oct 1;250(1):91-100.
Title:	Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs.
Author:	Akong, Kathryn\|Grevengoed, Elizabeth E\|Price, Meredith H\|McCartney, Brooke M\|Hayden, Melissa A\|DeNofrio, Jan C\|Peifer, Mark
PMID:	12297098

167.
Journal:	Cancer Lett. 2002 Dec 10;187(1-2):153-62.
Title:	Response to 5-fluorouracil chemotherapy is modified by dietary folic acid deficiency in Apc(Min/+) mice.
Author:	Tucker, Jody M\|Davis, Celestia\|Kitchens, Maria E\|Bunni, Marlene A\|Priest, David G\|Spencer, H Trent\|Berger, Franklin G
PMID:	12359363

168.
Journal:	Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13771-6. Epub 2002 Oct 7.
Title:	APC-dependent suppression of colon carcinogenesis by PPARgamma.
Author:	Girnun, Geoffrey D\|Smith, Wendy M\|Drori, Stavit\|Sarraf, Pasha\|Mueller, Elisabetta\|Eng, Charis\|Nambiar, Prashant\|Rosenberg, Daniel W\|Bronson, Roderick T\|Edelmann, Winfried\|Kucherlapati, Raju\|Gonzalez, Frank J\|Spiegelman, Bruce M
PMID:	12370429

169.
Journal:	Exp Cell Res. 2002 Oct 15;280(1):12-23.
Title:	Suppression of kinesin expression disrupts adenomatous polyposis coli (APC) localization and affects beta-catenin turnover in young adult mouse colon (YAMC) epithelial cells.
Author:	Cui, Hongyi\|Dong, Mei\|Sadhu, Devaki N\|Rosenberg, Daniel W
PMID:	12372335

170.
Journal:	Scand J Gastroenterol. 2002 Sep;37(9):1048-53.
Title:	Mutations of the APC gene in human sporadic colorectal cancers.
Author:	De Filippo, C\|Luceri, C\|Caderni, G\|Pacini, M\|Messerini, L\|Biggeri, A\|Mini, E\|Tonelli, F\|Cianchi, F\|Dolara, P
PMID:	12374230

171.
Journal:	Cancer Res. 2002 Oct 15;62(20):5651-6.
Title:	Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Author:	Takahashi, Meiko\|Fujita, Manabu\|Furukawa, Yoichi\|Hamamoto, Ryuji\|Shimokawa, Takashi\|Miwa, Nobutomo\|Ogawa, Michio\|Nakamura, Yusuke
PMID:	12384519

172.
Journal:	FEBS Lett. 2002 Oct 23;530(1-3):147-52.
Title:	Gut-enriched Kruppel-like factor regulates colonic cell growth through APC/beta-catenin pathway.
Author:	Stone, Christian D\|Chen, Zhi Y\|Tseng, Chi Chuan
PMID:	12387883

173.
Journal:	Cancer Res. 2002 Nov 15;62(22):6367-70.
Title:	Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice.
Author:	Yamada, Yasuhiro\|Hata, Kazuya\|Hirose, Yoshinobu\|Hara, Akira\|Sugie, Shigeyuki\|Kuno, Toshiya\|Yoshimi, Naoki\|Tanaka, Takuji\|Mori, Hideki
PMID:	12438216

174.
Journal:	J Cancer Res Clin Oncol. 2002 Nov;128(11):589-95.
Title:	Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane.
Author:	Kishimoto, Y\|Yashima, K\|Morisawa, T\|Ohishi, T\|Marumoto, A\|Sano, A\|Idobe-Fujii, Y\|Miura, N\|Shiota, G\|Murawaki, Y\|Hasegawa, J
PMID:	12458338

175.
Journal:	J Nutr. 2002 Dec;132(12):3804S-3808S.
Title:	Short chain fatty acids and colon cancer.
Author:	Augenlicht, Leonard H\|Mariadason, John M\|Wilson, Andrew\|Arango, Diego\|Yang, WanCai\|Heerdt, Barbara G\|Velcich, Anna
PMID:	12468628

176.
Journal:	Surg Clin North Am. 2002 Oct;82(5):891-904.
Title:	Pathogenesis of colorectal cancer.
Author:	Jass, Jeremy R
PMID:	12507199

177.
Journal:	Adv Exp Med Biol. 2002;507:127-31.
Title:	Modulation of cyclooxygenase-2 expression by APC in HT-29 human colorectal carcinoma cells.
Author:	Hsi, Linda C\|Angerman-Stewart, Julie\|Eling, Thomas E
PMID:	12664576

178.
Journal:	Mod Pathol. 2003 Jan;16(1):57-65.
Title:	Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
Author:	Venesio, Tiziana\|Balsamo, Antonella\|Scordamaglia, Antonella\|Bertolaso, Marta\|Arrigoni, Arrigo\|Sprujevnik, Tatiana\|Rossini, Francesco P\|Risio, Mauro
PMID:	12527714

179.
Journal:	Cancer Res. 2003 Feb 1;63(3):728-34.
Title:	Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.
Author:	Araki, Yuzuru\|Okamura, Shu\|Hussain, S Perwez\|Nagashima, Makoto\|He, Peijun\|Shiseki, Masayuki\|Miura, Koh\|Harris, Curtis C
PMID:	12566320

180.
Journal:	Mamm Genome. 2003 Feb;14(2):119-29.
Title:	Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.
Author:	Silverman, Karen A\|Koratkar, Revati A\|Siracusa, Linda D\|Buchberg, Arthur M
PMID:	12584607

181.
Journal:	EMBO J. 2003 Mar 3;22(5):1101-13.
Title:	Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription.
Author:	Rosin-Arbesfeld, Rina\|Cliffe, Adam\|Brabletz, Thomas\|Bienz, Mariann
PMID:	12606575

182.
Journal:	Comp Hepatol. 2003 Jan 31;2(1):3.
Title:	Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease.
Author:	Boitier, Eric\|Gautier, Jean-Charles\|Roberts, Ruth
PMID:	12622871

183.
Journal:	Mutat Res. 2003 Feb-Mar;523-524:99-107.
Title:	Chemoprevention of colon cancer by Korean food plant components.
Author:	Kim, Dae Joong\|Shin, Dong Hwan\|Ahn, Byeongwoo\|Kang, Jin Seok\|Nam, Ki Taek\|Park, Cheol Beom\|Kim, Cheul Kyu\|Hong, Jin Tae\|Kim, Yun-Bae\|Yun, Young Won\|Jang, Dong Deuk\|Yang, Ki-Hwa
PMID:	12628507

184.
Journal:	Virchows Arch. 2003 Mar;442(3):266-70. Epub 2003 Feb 11.
Title:	Expressions of two adenomatous polyposis coli and E-cadherin proteins on human colorectal cancers.
Author:	Furuta, Koh\|Yoshioka, Shingo\|Okabe, Satoko\|Ikeda, Masato\|Oginosawa, Mihoko\|Ikeda, Seiyo\|Nakayama, Yoshifuku\|Kikuchi, Masahiro\|Hamilton, Stanley R
PMID:	12647217

185.
Journal:	Carcinogenesis. 2003 Mar;24(3):605-11.
Title:	Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.
Author:	Yang, Kan\|Fan, Kunhua\|Kurihara, Naoto\|Shinozaki, Hiroharu\|Rigas, Basil\|Augenlicht, Leonard\|Kopelovich, Levy\|Edelmann, Winfried\|Kucherlapati, Raju\|Lipkin, Martin
PMID:	12663524

186.
Journal:	G Chir. 2003 Jan-Feb;24(1-2):39-42.
Title:	[Familial adenomatous polyposis: review of the literature and report of 3 cases].
Author:	Bronzino, P\|Rassu, P C\|Cassinelli, G\|Stanizzi, T\|Casaccia, M
PMID:	12728797

187.
Journal:	Gut. 2003 Jun;52(6):898-9.
Title:	Rapidly progressive adenomatous polyposis in a patient with germline mutations in both the APC and MLH1 genes: the worst of two worlds.
Author:	Scheenstra, R\|Rijcken, F E M\|Koornstra, J J\|Hollema, H\|Fodde, R\|Menko, F H\|Sijmons, R H\|Bijleveld, C M A\|Kleibeuker, J H
PMID:	12740349

188.
Journal:	Clin Sci (Lond). 2003 Sep;105(3):323-30.
Title:	Effect of epidermal growth factor administration on intestinal cell proliferation, crypt fission and polyp formation in multiple intestinal neoplasia (Min) mice.
Author:	Bashir, O\|Fitzgerald, A J\|Berlanga-Acosta, J\|Playford, R J\|Goodlad, R A
PMID:	12749762

189.
Journal:	Curr Pharm Des. 2003;9(24):1932-6.
Title:	P53 and beta-catenin in colorectal cancer progression.
Author:	Valentini, Anna Maria\|Pirrelli, Michele\|Renna, Letizia\|Armentano, Raffaele\|Caruso, Maria Lucia
PMID:	12871177

190.
Journal:	Am J Clin Oncol. 2003 Aug;26(4):S62-5.
Title:	Rofecoxib (Vioxx), a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer.
Author:	Evans, Jilly F
PMID:	12902858

191.
Journal:	Oncogene. 2003 Sep 4;22(38):6013-22.
Title:	Nuclear accumulation of full-length and truncated adenomatous polyposis coli protein in tumor cells depends on proliferation.
Author:	Fagman, Henrik\|Larsson, Fredrik\|Arvidsson, Yvonne\|Meuller, Johan\|Nordling, Margareta\|Martinsson, Tommy\|Helmbrecht, Karen\|Brabant, Georg\|Nilsson, Mikael
PMID:	12955080

192.
Journal:	Cancer Res. 2003 Sep 15;63(18):6090-5.
Title:	Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.
Author:	Niho, Naoko\|Takahashi, Mami\|Kitamura, Tomohiro\|Shoji, Yutaka\|Itoh, Masaki\|Noda, Tetsuo\|Sugimura, Takashi\|Wakabayashi, Keiji
PMID:	14522940

193.
Journal:	Nat Genet. 2003 Dec;35(4):323-30. Epub 2003 Nov 16.
Title:	Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Author:	Aoki, Koji\|Tamai, Yoshitaka\|Horiike, Shigeo\|Oshima, Masanobu\|Taketo, Makoto M
PMID:	14625550

194.
Journal:	Diagn Mol Pathol. 2003 Dec;12(4):187-92.
Title:	Colon cancer-associated DNA mutations: marker selection for the detection of proximal colon cancer.
Author:	Berger, Barry M\|Robison, Lauren\|Glickman, Jonathan
PMID:	14639104

195.
Journal:	Med Klin (Munich). 2003 Dec 15;98(12):776-82.
Title:	[Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
Author:	Friedrich, Anja\|Kullmann, Frank
PMID:	14685680

196.
Journal:	An R Acad Nac Med (Madr). 2003;120(3):545-55; discussion 555-7.
Title:	[Predictive molecular marker of distant metastasis in colorectal cancer].
Author:	Sanz Esponera, Julian
PMID:	15027705

197.
Journal:	Biochem Biophys Res Commun. 2004 Jan 16;313(3):784-8.
Title:	NO-donating aspirin inhibits intestinal carcinogenesis in Min (APC(Min/+)) mice.
Author:	Williams, Jennie L\|Kashfi, Khosrow\|Ouyang, Nengtai\|del Soldato, Piero\|Kopelovich, Levy\|Rigas, Basil
PMID:	14697260

198.
Journal:	Cancer Lett. 2004 Mar 31;206(1):107-13.
Title:	Wnt inhibitory factor-1: a candidate for a new player in tumorigenesis of intestinal epithelial cells.
Author:	Cebrat, Malgorzata\|Strzadala, Leon\|Kisielow, Pawel
PMID:	15019166

199.
Journal:	Biochem Biophys Res Commun. 2004 Apr 2;316(2):364-9.
Title:	MUC1 can interact with adenomatous polyposis coli in breast cancer.
Author:	Hattrup, Christine L\|Fernandez-Rodriguez, Julia\|Schroeder, Joyce A\|Hansson, Gunnar C\|Gendler, Sandra J
PMID:	15020226

200.
Journal:	Hum Mutat. 2004 Apr;23(4):397.
Title:	Molecular analysis of the APC and MYH genes in Czech families affected by FAP or multiple adenomas: 13 novel mutations.
Author:	Vandrovcova, J\|Stekrova, J\|Kebrdlova, V\|Kohoutova, M
PMID:	15024739

201.
Journal:	World J Gastroenterol. 2004 Mar 15;10(6):834-6.
Title:	Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients.
Author:	Huang, Jian\|Zheng, Shu\|Jin, Shen-Hang\|Zhang, Su-Zhan
PMID:	15040027

202.
Journal:	Mutat Res. 2004 Apr 14;548(1-2):107-16.
Title:	Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways.
Author:	Mabley, Jon G\|Pacher, Pal\|Bai, Peter\|Wallace, Rebecca\|Goonesekera, Sunali\|Virag, Laszlo\|Southan, Garry J\|Szabo, Csaba
PMID:	15063141

203.
Journal:	Fam Cancer. 2004;3(1):35-40.
Title:	Intron 4 mutation in APC gene results in splice defect and attenuated FAP phenotype.
Author:	Neklason, Deborah W\|Solomon, Cindy H\|Dalton, Amy L\|Kuwada, Scott K\|Burt, Randall W
PMID:	15131404

204.
Journal:	Wiad Lek. 2004;57(1-2):74-9.
Title:	[Genetic aspects of colorectal carcinogenesis].
Author:	Gonciarz, Maciej\|Pierzchalski, Piotr\|Lorens, Krzysztof\|Pawlik, Wieslaw\|Petelenz, Michal
PMID:	15181754

205.
Journal:	World J Surg. 2004 Jul;28(7):721-6.
Title:	Molecular detection of APC, K- ras, and p53 mutations in the serum of colorectal cancer patients as circulating biomarkers.
Author:	Wang, Jaw-Yuan\|Hsieh, Jan-Sing\|Chang, Mei-Yin\|Huang, Tsung-Jen\|Chen, Fang-Ming\|Cheng, Tian-Lu\|Alexandersen, Ketil\|Huang, Yu-Sheng\|Tzou, Wen-Shyong\|Lin, Shiu-Ru
PMID:	15185002

206.
Journal:	Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9769-73.
Title:	Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function.
Author:	Haigis, Kevin M\|Hoff, Peter D\|White, Alanna\|Shoemaker, Alex R\|Halberg, Richard B\|Dove, William F
PMID:	15210940

207.
Journal:	Br J Cancer. 2004 Jul 19;91(2):312-8.
Title:	Pathological features and genetic alterations in colorectal carcinomas with characteristics of nonpolypoid growth.
Author:	Kaneko, K\|Kurahashi, T\|Makino, R\|Konishi, K\|Ito, H\|Katagiri, A\|Kumekawa, Y\|Hirayama, Y\|Yoneyama, K\|Kushima, M\|Kusano, M\|Tajiri, H\|Rembacken, B J\|Mitamura, K\|Imawari, M
PMID:	15213719

208.
Journal:	Lab Invest. 2004 Dec;84(12):1619-30.
Title:	Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers.
Author:	Colnot, Sabine\|Niwa-Kawakita, Michiko\|Hamard, Ghislaine\|Godard, Cecile\|Le Plenier, Servane\|Houbron, Christophe\|Romagnolo, Beatrice\|Berrebi, Dominique\|Giovannini, Marco\|Perret, Christine
PMID:	15502862

209.
Journal:	Fam Cancer. 2004;3(3-4):215-21.
Title:	Genetic factors and colorectal cancer in Ashkenazi Jews.
Author:	Locker, Gershon Y\|Lynch, Henry T
PMID:	15516844

210.
Journal:	J Cell Sci. 2004 Dec 15;117(Pt 26):6339-53.
Title:	Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.
Author:	Tighe, Anthony\|Johnson, Victoria L\|Taylor, Stephen S
PMID:	15561772

211.
Journal:	J Biol Chem. 2005 Feb 25;280(8):6942-9. Epub 2004 Nov 16.
Title:	Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate.
Author:	Narayan, Satya\|Jaiswal, Aruna S\|Balusu, Ramesh
PMID:	15548520

212.
Journal:	DNA Cell Biol. 2005 Jan;24(1):21-9.
Title:	Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS.
Author:	Ramsay, Robert G\|Ciznadija, Daniel\|Sicurella, Catherine\|Reyes, Nancy\|Mitchelhill, Ken\|Darcy, Phillip K\|D'Abaco, Giovanna\|Mantamadiotis, Theo
PMID:	15684716

213.
Journal:	Int J Cancer. 2005 Jun 10;115(2):194-201.
Title:	Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells.
Author:	Sale, Stewart\|Tunstall, Richard G\|Ruparelia, Ketan C\|Potter, Gerry A\|Steward, William P\|Gescher, Andreas J
PMID:	15688382

214.
Journal:	Development. 2005 Mar;132(6):1443-51.
Title:	Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.
Author:	Andreu, Pauline\|Colnot, Sabine\|Godard, Cecile\|Gad, Sophie\|Chafey, Philippe\|Niwa-Kawakita, Michiko\|Laurent-Puig, Pierre\|Kahn, Axel\|Robine, Sylvie\|Perret, Christine\|Romagnolo, Beatrice
PMID:	15716339

215.
Journal:	Clin Genet. 2005 Apr;67(4):352-5.
Title:	The I1307K APC mutation in a high-risk clinic setting: a follow-up study.
Author:	Regev, M\|Barzilai, S-Eisenberg\|Figer, A\|Zidan, J\|Fidder, H H\|Friedman, E
PMID:	15733272

216.
Journal:	Genet Test. 2005 Spring;9(1):37-40.
Title:	APC germ-line mutations in southern Spanish patients with familial adenomatous polyposis: genotype-phenotype correlations and identification of eight novel mutations.
Author:	Garcia-Lozano, Jose-Raul\|Cordero, Carmen\|Fernandez-Suarez, Antonio\|Encarnacion, Mercedes\|Pizarro, Angeles\|Nunez-Roldan, Antonio
PMID:	15857185

217.
Journal:	Proteomics. 2005 Jul;5(10):2602-11.
Title:	Proteomic expression analysis of colorectal cancer by two-dimensional differential gel electrophoresis.
Author:	Alfonso, Patricia\|Nunez, Antonio\|Madoz-Gurpide, Juan\|Lombardia, Luis\|Sanchez, Lydia\|Casal, J Ignacio
PMID:	15924290

218.
Journal:	Clin Cancer Res. 2005 Jul 1;11(13):4689-93.
Title:	A homozygous mutation in MSH6 causes Turcot syndrome.
Author:	Hegde, Madhuri R\|Chong, Belinda\|Blazo, Maria E\|Chin, Lip Hon E\|Ward, Patricia A\|Chintagumpala, Murali M\|Kim, John Y\|Plon, Sharon E\|Richards, C Sue
PMID:	16000562

219.
Journal:	Nat Immunol. 2005 Aug;6(8):800-9. Epub 2005 Jul 17.
Title:	Loss of adenomatous polyposis coli gene function disrupts thymic development.
Author:	Gounari, Fotini\|Chang, Rui\|Cowan, Janet\|Guo, Zhuyan\|Dose, Marei\|Gounaris, Elias\|Khazaie, Khashayarsha
PMID:	16025118

220.
Journal:	Cancer Genet Cytogenet. 2005 Oct 1;162(1):68-73.
Title:	Who takes the lead in the development of ulcerative colitis-associated colorectal cancers: mutator, suppressor, or methylator pathway?
Author:	Maia, Lara\|Dinis, Joana\|Cravo, Marilia\|Claro, Isabel\|Baltazar, Celia\|Fonseca, Isabel\|Veloso, Tavarela\|Capelinha, Ana F\|Carneiro, Fatima\|Nobre-Leitao, Carlos
PMID:	16157203

221.
Journal:	Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5.
Title:	Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.
Author:	Yamada, Yasuhiro\|Jackson-Grusby, Laurie\|Linhart, Heinz\|Meissner, Alex\|Eden, Amir\|Lin, Haijiang\|Jaenisch, Rudolf
PMID:	16174748

222.
Journal:	Cancer Causes Control. 2005 Nov;16(9):1041-54.
Title:	Meat and fish consumption, APC gene mutations and hMLH1 expression in colon and rectal cancer: a prospective cohort study (The Netherlands).
Author:	Luchtenborg, Margreet\|Weijenberg, Matty P\|de Goeij, Anton F P M\|Wark, Petra A\|Brink, Mirian\|Roemen, Guido M J M\|Lentjes, Marjolein H F M\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van 't Veer, Pieter\|van den Brandt, Piet A
PMID:	16184469

223.
Journal:	Gene. 2005 Nov 21;361:1-12. Epub 2005 Sep 26.
Title:	Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein.
Author:	Hanson, Caroline A\|Miller, Jeffrey R
PMID:	16185824

224.
Journal:	Ann Chir. 2005 Dec;130(10):618-23.
Title:	[Multivisceral resections of extracolorectal lesions in familial adenomatous polyposis].
Author:	Godlewski, G\|Leborgne, J\|Lehur, A\|Deixonne, B\|Bourgaux, J-F\|Dehni, N\|Pujol, P\|Prudhomme, M
PMID:	16242660

225.
Journal:	BMC Cancer. 2005 Dec 15;5:160.
Title:	Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.
Author:	Luchtenborg, Margreet\|Weijenberg, Matty P\|Wark, Petra A\|Saritas, A Merdan\|Roemen, Guido M J M\|van Muijen, Goos N P\|de Bruine, Adriaan P\|van den Brandt, Piet A\|de Goeij, Anton F P M
PMID:	16356174

226.
Journal:	Cancer Res. 2005 Dec 15;65(24):11361-6.
Title:	CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
Author:	Kemp, Zoe\|Rowan, Andrew\|Chambers, William\|Wortham, Noel\|Halford, Sarah\|Sieber, Oliver\|Mortensen, Neil\|von Herbay, Axel\|Gunther, Thomas\|Ilyas, Mohammad\|Tomlinson, Ian
PMID:	16357143

227.
Journal:	Dis Colon Rectum. 2005 Dec;48(12):2343-6.
Title:	Pinealoblastoma in a patient with familial adenomatous polyposis: variant of Turcot syndrome type 2? Report of a case and review of the literature.
Author:	Gadish, T\|Tulchinsky, H\|Deutsch, A A\|Rabau, M
PMID:	16400511

228.
Journal:	Ned Tijdschr Geneeskd. 2005 Dec 31;149(53):2970-2.
Title:	[From gene to disease; MutYH-associated polyposis coli (MAP)].
Author:	Nielsen, M\|Weiss, M M\|Vasen, H F A\|Hes, F J
PMID:	16425850

229.
Journal:	Med Chem. 2005 Sep;1(5):467-72.
Title:	ICG-001, a novel small molecule regulator of TCF/beta-catenin transcription.
Author:	Eguchi, Masakatsu\|Nguyen, Cu\|Lee, Sung Chan\|Kahn, Michael
PMID:	16787331

230.
Journal:	Carcinogenesis. 2006 Feb;27(2):232-9.
Title:	NO-donating aspirin isomers downregulate peroxisome proliferator-activated receptor (PPAR)delta expression in APC(min/+) mice proportionally to their tumor inhibitory effect: Implications for the role of PPARdelta in carcinogenesis.
Author:	Ouyang, Nengtai\|Williams, Jennie L\|Rigas, Basil
PMID:	16141240

231.
Journal:	Int J Cancer. 2006 Apr 15;118(8):1937-40.
Title:	Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients.
Author:	Russell, Anna M\|Zhang, Jian\|Luz, Judith\|Hutter, Pierre\|Chappuis, Pierre O\|Berthod, Claudine Rey\|Maillet, Philippe\|Mueller, Hansjakob\|Heinimann, Karl
PMID:	16287072

232.
Journal:	J Biol Chem. 2006 Feb 3;281(5):2676-82. Epub 2005 Nov 17.
Title:	Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer.
Author:	Holla, Vijaykumar R\|Mann, Jason R\|Shi, Qiong\|DuBois, Raymond N
PMID:	16293616

233.
Journal:	Cancer Res. 2006 Feb 15;66(4):1949-55.
Title:	Identification of the IFITM family as a new molecular marker in human colorectal tumors.
Author:	Andreu, Pauline\|Colnot, Sabine\|Godard, Cecile\|Laurent-Puig, Pierre\|Lamarque, Dominique\|Kahn, Axel\|Perret, Christine\|Romagnolo, Beatrice
PMID:	16488993

234.
Journal:	BMC Cancer. 2006 Mar 29;6:83.
Title:	Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan.
Author:	Chen, Shee-Ping\|Tsai, Shih-Tzu\|Jao, Shu-Wen\|Huang, Yen-Lun\|Chao, Yu-Chen\|Chen, Yi-Lin\|Wu, Chang-Chieh\|Lin, Shinn-Zong\|Harn, Horng-Jyh
PMID:	16569251

235.
Journal:	Orv Hetil. 2006 Feb 26;147(8):363-8.
Title:	[Current concepts in the genetics of hereditary and sporadic colorectal cancer and the role of genetics in patient management. Hereditary colorectal cancers].
Author:	Lakatos, Peter Laszlo\|Lakatos, Laszlo
PMID:	16579336

236.
Journal:	Carcinogenesis. 2006 Jul;27(7):1507-15. Epub 2006 Apr 5.
Title:	Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line.
Author:	Fenton, Jenifer I\|Hursting, Stephen D\|Perkins, Susan N\|Hord, Norman G
PMID:	16597643

237.
Journal:	Biol Chem. 2006 Apr;387(4):381-5.
Title:	Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice.
Author:	Mutoh, Michihiro\|Niho, Naoko\|Wakabayashi, Keiji
PMID:	16606335

238.
Journal:	Cancer Sci. 2006 May;97(5):355-61.
Title:	Mouse models of gastrointestinal tumors.
Author:	Taketo, Makoto Mark
PMID:	16630131

239.
Journal:	Clin Genet. 2006 May;69(5):404-9.
Title:	Novel germline mutations in the APC gene of Cypriot patients with familial and sporadic adenomatous polyposis.
Author:	Hadjisavvas, A\|Papasavva, T\|Loizidou, M\|Malas, S\|Potamitis, G\|Christodoulou, C\|Pavlides, G\|Papamichael, D\|Klonis, C\|Nasioulas, G\|Anastasiadou, V\|Kyriacou, K
PMID:	16650078

240.
Journal:	Int J Oncol. 2006 Jun;28(6):1523-9.
Title:	Prevention of early-onset familial/hereditary colon cancer: new models and mechanistic biomarkers (review).
Author:	Telang, Nitin T\|Li, Guo\|Katdare, Meena
PMID:	16685453

241.
Journal:	J Biol Chem. 2006 Jul 21;281(29):20474-82. Epub 2006 May 14.
Title:	The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.
Author:	Eisinger, Annie L\|Nadauld, Lincoln D\|Shelton, Dawne N\|Peterson, Peter W\|Phelps, Reid A\|Chidester, Stephanie\|Stafforini, Diana M\|Prescott, Stephen M\|Jones, David A
PMID:	16699180

242.
Journal:	Int J Exp Pathol. 2006 Jun;87(3):227-36.
Title:	Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice.
Author:	You, Shaojin\|Ohmori, Masami\|Pena, Maria Marjorette O\|Nassri, Basel\|Quiton, Jovelyn\|Al-Assad, Ziad A\|Liu, Lucy\|Wood, Patricia A\|Berger, Sondra H\|Liu, Zhijian\|Wyatt, Michael D\|Price, Robert L\|Berger, Franklin G\|Hrushesky, William J M
PMID:	16709231

243.
Journal:	Toxicol Sci. 2006 Oct;93(2):286-97.
Title:	Uranyl nitrilotriacetate, a stabilized salt of uranium, is genotoxic in nontransformed human colon cells and in the human colon adenoma cell line LT97.
Author:	Knobel, Yuonne\|Glei, Michael\|Weise, Anja\|Osswald, Kerstin\|Schaferhenrich, Anja\|Richter, Konrad Klaus\|Claussen, Uwe\|Pool-Zobel, Beatrice Louise
PMID:	16840563

244.
Journal:	Cancer Genet Cytogenet. 2006 Aug;169(1):33-8.
Title:	The I1307K APC polymorphism in Ashkenazi Jews with colorectal cancer: clinical and pathologic features.
Author:	Locker, Gershon Y\|Kaul, Karen\|Weinberg, David S\|Gatalica, Zoran\|Gong, Gordon\|Peterman, Amy\|Lynch, Jane\|Klatzco, Lucy\|Olopade, Olufunmilayo I\|Bomzer, Charles A\|Newlin, Anna\|Keenan, Eileen\|Tajuddin, Mohammed\|Knezetic, Joseph\|Coronel, Stephanie\|Lynch, Henry
PMID:	16875934

245.
Journal:	Fam Cancer. 2006;5(4):397-404.
Title:	Congenital hypertrophy of the retinal pigment epithelium (CHRPE) in familial colorectal cancer.
Author:	Chen, Celia S\|Phillips, Kerry D\|Grist, Scott\|Bennet, Graeme\|Craig, Jamie E\|Muecke, James S\|Suthers, Graeme K
PMID:	16944273

246.
Journal:	Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14122-7. Epub 2006 Sep 7.
Title:	Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo.
Author:	Sansom, Owen J\|Meniel, Valerie\|Wilkins, Julie A\|Cole, Alicia M\|Oien, Karin A\|Marsh, Victoria\|Jamieson, Thomas J\|Guerra, Carmen\|Ashton, Gabrielle H\|Barbacid, Mariano\|Clarke, Alan R
PMID:	16959882

247.
Journal:	Cancer Res. 2006 Oct 15;66(20):9837-44.
Title:	Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.
Author:	Munoz, Nina M\|Upton, Melissa\|Rojas, Andres\|Washington, M Kay\|Lin, Li\|Chytil, Anna\|Sozmen, Elif G\|Madison, Blair B\|Pozzi, Ambra\|Moon, Randall T\|Moses, Harold L\|Grady, William M
PMID:	17047044

248.
Journal:	Cancer Res. 2006 Oct 15;66(20):10127-35.
Title:	Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector.
Author:	Kuroda, Toshihiko\|Rabkin, Samuel D\|Martuza, Robert L
PMID:	17047077

249.
Journal:	J Nutr. 2006 Dec;136(12):3015-21.
Title:	Dietary folate and APC mutations in sporadic colorectal cancer.
Author:	de Vogel, Stefan\|van Engeland, Manon\|Luchtenborg, Margreet\|de Bruine, Adriaan P\|Roemen, Guido M J M\|Lentjes, Marjolein H F M\|Goldbohm, R Alexandra\|van den Brandt, Piet A\|de Goeij, Anton F P M\|Weijenberg, Matty P
PMID:	17116713

250.
Journal:	Oncogene. 2006 Dec 4;25(57):7531-7.
Title:	Colorectal cancer and genetic alterations in the Wnt pathway.
Author:	Segditsas, S\|Tomlinson, I
PMID:	17143297

251.
Journal:	Genome Dyn. 2006;1:149-70.
Title:	The role of the APC tumor suppressor in chromosomal instability.
Author:	Alberici, P\|Fodde, R
PMID:	18724059

252.
Journal:	Cancer Sci. 2007 Jan;98(1):6-10.
Title:	Multistep carcinogenesis of the colon in Apc(Min/+) mouse.
Author:	Yamada, Yasuhiro\|Mori, Hideki
PMID:	17052257

253.
Journal:	Am J Pathol. 2007 Jan;170(1):377-87.
Title:	Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human.
Author:	Alberici, Paola\|de Pater, Emma\|Cardoso, Joana\|Bevelander, Mieke\|Molenaar, Lia\|Jonkers, Jos\|Fodde, Riccardo
PMID:	17200209

254.
Journal:	Cancer Res. 2007 Jan 15;67(2):445-9.
Title:	Frequent mutation of Apc gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis.
Author:	Femia, Angelo Pietro\|Dolara, Piero\|Giannini, Augusto\|Salvadori, Maddalena\|Biggeri, Annibale\|Caderni, Giovanna
PMID:	17234750

255.
Journal:	J Biol Chem. 2007 Apr 27;282(17):12661-8. Epub 2007 Feb 8.
Title:	Regulated binding of adenomatous polyposis coli protein to actin.
Author:	Moseley, James B\|Bartolini, Francesca\|Okada, Kyoko\|Wen, Ying\|Gundersen, Gregg G\|Goode, Bruce L
PMID:	17293347

256.
Journal:	Oncogene. 2007 Jul 19;26(33):4872-6. Epub 2007 Feb 5.
Title:	Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis.
Author:	Qian, J\|Steigerwald, K\|Combs, K A\|Barton, M C\|Groden, J
PMID:	17297457

257.
Journal:	Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4036-41. Epub 2007 Feb 27.
Title:	A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer.
Author:	Amos-Landgraf, James M\|Kwong, Lawrence N\|Kendziorski, Christina M\|Reichelderfer, Mark\|Torrealba, Jose\|Weichert, Jamey\|Haag, Jill D\|Chen, Kai-Shun\|Waller, Jordy L\|Gould, Michael N\|Dove, William F
PMID:	17360473

258.
Journal:	Nat Genet. 2007 Apr;39(4):467-75. Epub 2007 Mar 18.
Title:	SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion.
Author:	Kitamura, Takanori\|Kometani, Kohei\|Hashida, Hiroki\|Matsunaga, Akihiro\|Miyoshi, Hiroyuki\|Hosogi, Hisahiro\|Aoki, Masahiro\|Oshima, Masanobu\|Hattori, Masakazu\|Takabayashi, Arimichi\|Minato, Nagahiro\|Taketo, Makoto M
PMID:	17369830

259.
Journal:	Nature. 2007 Apr 5;446(7136):676-9. Epub 2007 Mar 21.
Title:	Myc deletion rescues Apc deficiency in the small intestine.
Author:	Sansom, Owen J\|Meniel, Valerie S\|Muncan, Vanesa\|Phesse, Toby J\|Wilkins, Julie A\|Reed, Karen R\|Vass, J Keith\|Athineos, Dimitris\|Clevers, Hans\|Clarke, Alan R
PMID:	17377531

260.
Journal:	Genome Res. 2007 May;17(5):566-76. Epub 2007 Mar 26.
Title:	The modifier of Min 2 (Mom2) locus: embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression.
Author:	Baran, Amy A\|Silverman, Karen A\|Zeskand, Joseph\|Koratkar, Revati\|Palmer, Ashley\|McCullen, Kristen\|Curran, Walter J Jr\|Edmonston, Tina Bocker\|Siracusa, Linda D\|Buchberg, Arthur M
PMID:	17387143

261.
Journal:	Cancer Cell. 2007 May;11(5):391-4.
Title:	Role of c-Myc in Apc mutant intestinal phenotype: case closed or time for a new beginning?
Author:	Bommer, Guido T\|Fearon, Eric R
PMID:	17482129

262.
Journal:	Am J Clin Nutr. 2007 Jun;85(6):1592-7.
Title:	The D1822V APC polymorphism interacts with fat, calcium, and fiber intakes in modulating the risk of colorectal cancer in Portuguese persons.
Author:	Guerreiro, Catarina S\|Cravo, Marilia L\|Brito, Miguel\|Vidal, Pedro M\|Fidalgo, Paulo O\|Leitao, Carlos N
PMID:	17556698

263.
Journal:	Int J Cancer. 2007 Oct 15;121(8):1717-23.
Title:	Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer.
Author:	Rohde, Franziska\|Rimkus, Caroline\|Friederichs, Jan\|Rosenberg, Robert\|Marthen, Carmen\|Doll, Dietrich\|Holzmann, Bernhard\|Siewert, Jorg-Rudiger\|Janssen, Klaus-Peter
PMID:	17565744

264.
Journal:	Gastroenterology. 2007 Jun;132(7):2448-58. Epub 2007 Mar 19.
Title:	APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation.
Author:	Abal, Miguel\|Obrador-Hevia, Antonia\|Janssen, Klaus-Peter\|Casadome, Laura\|Menendez, Mireia\|Carpentier, Sabrina\|Barillot, Emmanuel\|Wagner, Mechthild\|Ansorge, Wilhelm\|Moeslein, Gabriela\|Fsihi, Hafida\|Bezrookove, Vladimir\|Reventos, Jaume\|Louvard, Daniel\|Capel
PMID:	17570218

265.
Journal:	Acta Oncol. 2007;46(6):757-62.
Title:	May the APC gene somatic mutations in tumor tissues influence the clinical features of Chinese sporadic colorectal cancers?
Author:	Liu, Xiaorong\|Shan, Xiangnian\|Friedl, Waltraut\|Uhlhaas, Siegfried\|Propping, Peter\|Li, Jintian\|Wang, Yaping
PMID:	17653897

266.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jul;27(7):1018-21.
Title:	[Value of fecal and blood adenomatous polyposis coli gene and K-ras gene mutation detection in colorectal neoplasm screening].
Author:	Zhan, Jun\|Li, Xin\|Yu, Zhong\|Yuan, Yu-hong\|Hou, Jing
PMID:	17666342

267.
Journal:	Cancer Res. 2007 Aug 1;67(15):7147-54.
Title:	Haploinsufficiency of Kruppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.
Author:	Ghaleb, Amr M\|McConnell, Beth B\|Nandan, Mandayam O\|Katz, Jonathan P\|Kaestner, Klaus H\|Yang, Vincent W
PMID:	17671182

268.
Journal:	Gastroenterology. 2007 Aug;133(2):599-607. Epub 2007 Jun 2.
Title:	Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Author:	Li, Peng\|Schulz, Stephanie\|Bombonati, Alessandro\|Palazzo, Juan P\|Hyslop, Terry M\|Xu, Yihuan\|Baran, Amy A\|Siracusa, Linda D\|Pitari, Giovanni M\|Waldman, Scott A
PMID:	17681179

269.
Journal:	Chirurgia (Bucur). 2007 May-Jun;102(3):277-80.
Title:	[When and what will we do with the descendants of colorectal cancer patients? Case study and research project presentation].
Author:	Belusica, L\|Cimponeriu, D\|Dumitrescu, Ioana\|Gherghinoiu, Roni\|Hortopan, Andreea\|Constantinescu, G\|Predescu, Gabriela\|Doran, H\|Patrascu, Tr
PMID:	17687855

270.
Journal:	Nat Struct Mol Biol. 2007 Sep;14(9):814-23. Epub 2007 Aug 19.
Title:	Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Author:	Mitin, Natalia\|Betts, Laurie\|Yohe, Marielle E\|Der, Channing J\|Sondek, John\|Rossman, Kent L
PMID:	17704816

271.
Journal:	Cancer Genet Cytogenet. 2007 Sep;177(2):95-7.
Title:	How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population.
Author:	Dundar, Munis\|Caglayan, Ahmet Okay\|Saatci, Cetin\|Karaca, Hatice\|Baskol, Mevlut\|Tahiri, Serpil\|Ozkul, Yusuf
PMID:	17854661

272.
Journal:	Gastroenterology. 2007 Nov;133(5):1554-68. Epub 2007 Oct 24.
Title:	Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Author:	Pannequin, Julie\|Delaunay, Nathalie\|Buchert, Michael\|Surrel, Fanny\|Bourgaux, Jean-Francois\|Ryan, Joanne\|Boireau, Stephanie\|Coelho, Jessica\|Pelegrin, Andre\|Singh, Pomila\|Shulkes, Arthur\|Yim, Mildred\|Baldwin, Graham S\|Pignodel, Christine\|Lambeau, Gerard\|Jay
PMID:	17920061

273.
Journal:	Cancer Res. 2007 Oct 15;67(20):9721-30.
Title:	Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation.
Author:	Hinoi, Takao\|Akyol, Aytekin\|Theisen, Brian K\|Ferguson, David O\|Greenson, Joel K\|Williams, Bart O\|Cho, Kathleen R\|Fearon, Eric R
PMID:	17942902

274.
Journal:	Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18199-204. Epub 2007 Nov 7.
Title:	Alpha-catenin is essential in intestinal adenoma formation.
Author:	Shibata, Hiroyuki\|Takano, Hiroshi\|Ito, Masaki\|Shioya, Hisashi\|Hirota, Morihisa\|Matsumoto, Hiroshi\|Kakudo, Yuichi\|Ishioka, Chikashi\|Akiyama, Tetsu\|Kanegae, Yumi\|Saito, Izumu\|Noda, Tetsuo
PMID:	17989230

275.
Journal:	Genes Cells. 2007 Dec;12(12):1339-45.
Title:	Putative tumor suppressor EDD interacts with and up-regulates APC.
Author:	Ohshima, Ryuichi\|Ohta, Tomohiko\|Wu, Wenwen\|Koike, Ayaka\|Iwatani, Tsuguo\|Henderson, Michelle\|Watts, Colin K W\|Otsubo, Takehito
PMID:	18076571

276.
Journal:	Genet Med. 2007 Dec;9(12):836-41.
Title:	Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
Author:	Cattaneo, Francesca\|Molatore, Sara\|Mihalatos, Markos\|Apessos, Angela\|Venesio, Tiziana\|Bione, Silvia\|Grignani, Pierangela\|Nasioulas, Georgios\|Ranzani, Guglielmina Nadia
PMID:	18091433

277.
Journal:	Mol Cancer Res. 2007 Dec;5(12):1296-303.
Title:	Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.
Author:	Yekkala, Krishna\|Baudino, Troy A
PMID:	18171987

278.
Journal:	Med Arh. 2007;61(4):256-9.
Title:	Genetics, clinical manifestations and management of FAP and HNPCC.
Author:	Pavlovic-Calic, Nada\|Muminhodzic, Kasim\|Zildzic, Muharem\|Smajic, Midhat\|Gegic, Adnan\|Alibegovic, Ervin\|Salkic, Nermin\|Jovanovic, Predrag\|Basic, Mirela\|Iljazovic, Samra
PMID:	18298004

279.
Journal:	Mol Carcinog. 2008 Jan;47(1):9-21.
Title:	Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
Author:	Fenton, Jenifer I\|Lavigne, Jackie A\|Perkins, Susan N\|Liu, Huaitian\|Chandramouli, Gadisetti V R\|Shih, Joanna H\|Hord, Norman G\|Hursting, Stephen D
PMID:	17620308

280.
Journal:	Br J Nutr. 2008 Mar;99(3):550-8.
Title:	Gender-specific modulation of tumorigenesis by folic acid supply in the Apc mouse during early neonatal life.
Author:	McKay, Jill A\|Williams, Elizabeth A\|Mathers, John C
PMID:	17868491

281.
Journal:	Int J Mol Med. 2008 Jan;21(1):19-31.
Title:	Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor.
Author:	Kurzik-Dumke, Ursula\|Horner, Manuela\|Czaja, Joachim\|Nicotra, Maria Rita\|Simiantonaki, Nektaria\|Koslowski, Michael\|Natali, Pier Giorgio
PMID:	18097612

282.
Journal:	J Biol Chem. 2008 Feb 29;283(9):5950-9. Epub 2007 Dec 26.
Title:	Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival.
Author:	Brocardo, Mariana\|Lei, Ying\|Tighe, Anthony\|Taylor, Stephen S\|Mok, Myth T S\|Henderson, Beric R
PMID:	18160396

283.
Journal:	Acad Radiol. 2008 Mar;15(3):334-41.
Title:	Reproducibility of tumor volume measurement at microCT colonography in living mice.
Author:	Durkee, Benjamin Y\|Mudd, Sarah R\|Roen, Calista N\|Clipson, Linda\|Newton, Michael A\|Weichert, Jamey P\|Pickhardt, Perry J\|Halberg, Richard B
PMID:	18280931

284.
Journal:	Am J Pathol. 2008 May;172(5):1363-80.
Title:	Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
Author:	Gaspar, Claudia\|Cardoso, Joana\|Franken, Patrick\|Molenaar, Lia\|Morreau, Hans\|Moslein, Gabriela\|Sampson, Julian\|Boer, Judith M\|de Menezes, Renee X\|Fodde, Riccardo
PMID:	18403596

285.
Journal:	Infect Immun. 2008 Jun;76(6):2758-66.
Title:	Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc(Min/+) mouse.
Author:	Nagamine, Claude M\|Sohn, Jane J\|Rickman, Barry H\|Rogers, Arlin B\|Fox, James G\|Schauer, David B
PMID:	18411292

286.
Journal:	Gastroenterology. 2008 Jul;135(1):152-62.
Title:	The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus.
Author:	Qian, Jiang\|Sarnaik, Amod A\|Bonney, Tera M\|Keirsey, Jeremy\|Combs, Kelly A\|Steigerwald, Kira\|Acharya, Samir\|Behbehani, Gregory K\|Barton, Michelle C\|Lowy, Andrew M\|Groden, Joanna
PMID:	18474248

287.
Journal:	Exp Mol Pathol. 2008 Aug;85(1):64-7.
Title:	Genetic and epigenetic changes in colon cancer.
Author:	Samowitz, Wade S
PMID:	18482722

288.
Journal:	Biochim Biophys Acta. 2008 Oct;1783(10):1792-802.
Title:	The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members.
Author:	Breitman, Maya\|Zilberberg, Alona\|Caspi, Michal\|Rosin-Arbesfeld, Rina
PMID:	18502210

289.
Journal:	Pathol Res Pract. 2008;204(7):479-90.
Title:	Apc mice: models, modifiers and mutants.
Author:	McCart, Amy E\|Vickaryous, Nicola K\|Silver, Andrew
PMID:	18538487

290.
Journal:	J Clin Oncol. 2008 Jun 10;26(17):2828-38.
Title:	Human colon cancer stem cells: a new paradigm in gastrointestinal oncology.
Author:	Boman, Bruce M\|Huang, Emina
PMID:	18539961

291.
Journal:	Dis Colon Rectum. 2008 Oct;51(10):1467-73; discussion 1473-4.
Title:	Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk.
Author:	Cleary, Sean P\|Kim, Hyeja\|Croitoru, Marina E\|Redston, Mark\|Knight, Julia A\|Gallinger, Steven\|Gryfe, Robert
PMID:	18612690

292.
Journal:	Cas Lek Cesk. 2008;147(5):266-8.
Title:	[Single nucleotide c.645+32c>T substitution in the APC gene is a non-pathogenic polymorphism appearing in about 16% of the Czech population].
Author:	Plevova, P\|Drobcinska, L\|Stekrova, J\|Silhanova, E
PMID:	18630182

293.
Journal:	Cancer Res. 2008 Jul 15;68(14):5795-802.
Title:	Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer.
Author:	Nagel, Remco\|le Sage, Carlos\|Diosdado, Begona\|van der Waal, Maike\|Oude Vrielink, Joachim A F\|Bolijn, Anne\|Meijer, Gerrit A\|Agami, Reuven
PMID:	18632633

294.
Journal:	J Exp Med. 2008 Sep 1;205(9):2163-75.
Title:	A critical role for Apc in hematopoietic stem and progenitor cell survival.
Author:	Qian, Zhijian\|Chen, Lina\|Fernald, Anthony A\|Williams, Bart O\|Le Beau, Michelle M
PMID:	18725524

295.
Journal:	Int J Obes (Lond). 2008 Nov;32(11):1716-9.
Title:	Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.
Author:	Gravaghi, C\|Bo, J\|Laperle, K M D\|Quimby, F\|Kucherlapati, R\|Edelmann, W\|Lamprecht, S A
PMID:	18725892

296.
Journal:	Cancer Res. 2008 Sep 15;68(18):7313-22.
Title:	Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.
Author:	Yang, Kan\|Popova, Natalia V\|Yang, Wan Cai\|Lozonschi, Ioanna\|Tadesse, Selam\|Kent, Scott\|Bancroft, Laura\|Matise, Ilze\|Cormier, Robert T\|Scherer, Stefan J\|Edelmann, Winfried\|Lipkin, Martin\|Augenlicht, Leonard\|Velcich, Anna
PMID:	18794118

297.
Journal:	Cancer Res. 2008 Sep 15;68(18):7579-86.
Title:	One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis.
Author:	Yeung, Anthony T\|Patel, Bhavinkumar B\|Li, Xin-Ming\|Seeholzer, Steven H\|Coudry, Renata A\|Cooper, Harry S\|Bellacosa, Alfonso\|Boman, Bruce M\|Zhang, Tao\|Litwin, Samuel\|Ross, Eric A\|Conrad, Peggy\|Crowell, James A\|Kopelovich, Levy\|Knudson, Alfred
PMID:	18794146

298.
Journal:	Surgeon. 2008 Dec;6(6):350-6.
Title:	Prognostic and therapeutic implications of Apc mutations in colorectal cancer.
Author:	Quyn, A J\|Steele, R J C\|Carey, F A\|Nathke, I S
PMID:	19110823

299.
Journal:	Cancer Prev Res (Phila). 2008 Dec;1(7):562-7.
Title:	Identification of mucin depleted foci in the human colon.
Author:	Femia, Angelo Pietro\|Giannini, Augusto\|Fazi, Marilena\|Tarquini, Elena\|Salvadori, Maddalena\|Roncucci, Luca\|Tonelli, Francesco\|Dolara, Piero\|Caderni, Giovanna
PMID:	19139006

300.
Journal:	Clin Transl Sci. 2008 Sep;1(2):146-50.
Title:	Sex modulates intestinal transformation by the tumor-suppressor GCC.
Author:	Li, Peng\|Schulz, Stephanie\|Pitari, Giovanni M\|Waldman, Scott A
PMID:	20443837

301.
Journal:	Pathol Biol (Paris). 2009 May;57(3):e67-71.
Title:	No evidence of the APC D1822V missense variant's pathogenicity in Tunisian patients with sporadic colorectal cancer.
Author:	Bougatef, K\|Marrakchi, R\|Ouerhani, S\|Sassi, R\|Moussa, A\|Kourda, N\|Blondeau Lahely, Y\|Najjar, T\|Ben Jilani, S\|Soubrier, F\|Ben Ammar Elgaaied, A
PMID:	18343606

302.
Journal:	Mol Carcinog. 2009 Feb;48(2):156-66.
Title:	Src transformation of colonic epithelial cells: enhanced anchorage-independent growth in an Apc(+/min) background.
Author:	Constancio-Lund, Sabata S\|Brabek, Jan\|Hanks, Steven K
PMID:	18613032

303.
Journal:	Lab Invest. 2009 Jan;89(1):98-105.
Title:	Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas.
Author:	Kitamura, Takanori\|Biyajima, Kyoko\|Aoki, Masahiro\|Oshima, Masanobu\|Taketo, Makoto M
PMID:	19002110

304.
Journal:	Mol Carcinog. 2009 May;48(5):401-7.
Title:	Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer.
Author:	Elander, Nils\|Zhou, Jianlin\|Ungerback, Jonas\|Dimberg, Jan\|Soderkvist, Peter
PMID:	19035518

305.
Journal:	Gut. 2009 Jun;58(6):805-11.
Title:	Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
Author:	Lawrance, A K\|Deng, L\|Rozen, R
PMID:	19174418

306.
Journal:	Cancer Prev Res (Phila). 2009 Mar;2(3):224-33.
Title:	Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis.
Author:	Hung, Kenneth E\|Faca, Vitor\|Song, Kenneth\|Sarracino, David A\|Richard, Larissa Georgeon\|Krastins, Bryan\|Forrester, Sara\|Porter, Andrew\|Kunin, Alexandra\|Mahmood, Umar\|Haab, Brian B\|Hanash, Samir M\|Kucherlapati, Raju
PMID:	19240248

307.
Journal:	Gastroenterology. 2009 Jun;136(7):2204-2213.e1-13.
Title:	The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.
Author:	Pollard, Patrick\|Deheragoda, Maesha\|Segditsas, Stefania\|Lewis, Annabelle\|Rowan, Andrew\|Howarth, Kimberley\|Willis, Lisa\|Nye, Emma\|McCart, Amy\|Mandir, Nikki\|Silver, Andrew\|Goodlad, Robert\|Stamp, Gordon\|Cockman, Matthew\|East, Philip\|Spencer-Dene, Bradley\|Pou
PMID:	19248780

308.
Journal:	Mol Biol Cell. 2009 May;20(9):2381-8.
Title:	Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2.
Author:	Zhang, Jiayin\|Neisa, Roberto\|Mao, Yinghui
PMID:	19261806

309.
Journal:	Anticancer Res. 2009 Feb;29(2):711-5.
Title:	Initial results of colorectal polyposis research in Latvia.
Author:	Borosenko, Viktors\|Irmejs, Arvids\|Melbarde-Gorkusa, Inga\|Gardovskis, Andris\|Pavars, Maris\|Vanags, Andrejs\|Trofimovics, Genadijs\|Miklasevics, Edvins\|Gardovskis, Janis
PMID:	19331226

310.
Journal:	Mol Carcinog. 2009 Oct;48(10):942-52.
Title:	Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
Author:	Foreman, Jennifer E\|Sorg, Joseph M\|McGinnis, Kathleen S\|Rigas, Basil\|Williams, Jennie L\|Clapper, Margie L\|Gonzalez, Frank J\|Peters, Jeffrey M
PMID:	19415698

311.
Journal:	Carcinogenesis. 2009 Jul;30(7):1217-24.
Title:	5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model.
Author:	Koelink, Pim J\|Robanus-Maandag, Els C\|Devilee, Peter\|Hommes, Daniel W\|Lamers, Cornelis B H W\|Verspaget, Hein W
PMID:	19420017

312.
Journal:	Gastroenterology. 2009 Sep;137(3):914-23.
Title:	Saccharomyces boulardii inhibits EGF receptor signaling and intestinal tumor growth in Apc(min) mice.
Author:	Chen, Xinhua\|Fruehauf, Johannes\|Goldsmith, Jeffrey D\|Xu, Hua\|Katchar, Kianoosh K\|Koon, Hon-Wai\|Zhao, Dezheng\|Kokkotou, Efi G\|Pothoulakis, Charalabos\|Kelly, Ciaran P
PMID:	19482027

313.
Journal:	J Biol Chem. 2009 Aug 14;284(33):22436-43.
Title:	Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase.
Author:	Kawasaki, Yoshihiro\|Tsuji, Shinnosuke\|Sagara, Masaki\|Echizen, Kanae\|Shibata, Yoko\|Akiyama, Tetsu
PMID:	19525225

314.
Journal:	Int J Colorectal Dis. 2009 Oct;24(10):1141-8.
Title:	Analysis of mutations in TP53, APC, K-ras, and DCC genes in the non-dysplastic mucosa of patients with inflammatory bowel disease.
Author:	Rapozo, Davy Carlos Mendes\|Grinmann, Ana Braunstein\|Carvalho, Ana Teresa Pugas\|de Souza, Heitor Siffert P\|Soares-Lima, Sheila Coelho\|de Almeida Simao, Tatiana\|de Paiva, Daurita\|Abby, Flavio\|Albano, Rodolpho Mattos\|Pinto, Luiz Felipe Ribeiro
PMID:	19543899

315.
Journal:	PLoS Genet. 2009 Jul;5(7):e1000547.
Title:	A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
Author:	Gaspar, Claudia\|Franken, Patrick\|Molenaar, Lia\|Breukel, Cor\|van der Valk, Martin\|Smits, Ron\|Fodde, Riccardo
PMID:	19578404

316.
Journal:	Scand J Gastroenterol. 2009;44(9):1092-100.
Title:	Relative role of APC and MUTYH mutations in the pathogenesis of familial adenomatous polyposis.
Author:	Pezzi, Annalisa\|Roncucci, Luca\|Benatti, Piero\|Sassatelli, Romano\|Varesco, Liliana\|Di Gregorio, Carmela\|Venesio, Tiziana\|Pedroni, Monica\|Maffei, Stefania\|Reggiani Bonetti, Luca\|Borsi, Enrica\|Ferrari, Maurizio\|Martella, Pietro\|Rossi, Giuseppina\|Ponz De Leon
PMID:	19593690

317.
Journal:	Cell Cycle. 2009 Sep 15;8(18):2926-31. Epub 2009 Sep 8.
Title:	APC as a master regulator of intestinal homeostasis and transformation: from flies to vertebrates.
Author:	Cordero, Julia\|Vidal, Marcos\|Sansom, Owen
PMID:	19657225

318.
Journal:	Cancer Sci. 2009 Nov;100(11):2022-7.
Title:	Enhanced colitis-associated colon carcinogenesis in a novel Apc mutant rat.
Author:	Yoshimi, Kazuto\|Tanaka, Takuji\|Takizawa, Akiko\|Kato, Megumi\|Hirabayashi, Masumi\|Mashimo, Tomoji\|Serikawa, Tadao\|Kuramoto, Takashi
PMID:	19694754

319.
Journal:	Carcinogenesis. 2009 Nov;30(11):1923-6.
Title:	Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.
Author:	Itano, Osamu\|Yang, Kan\|Fan, Kunhua\|Kurihara, Naoto\|Shinozaki, Hiroharu\|Abe, Sadanori\|Jin, Bo\|Gravaghi, Claudia\|Edelmann, Winfried\|Augenlicht, Leonard\|Kopelovich, Levy\|Kucherlapati, Raju\|Lamprecht, Sergio\|Lipkin, Martin
PMID:	19755659

320.
Journal:	Cell Oncol. 2009;31(5):345-56.
Title:	Pla2g2a attenuates colon tumorigenesis in azoxymethane-treated C57BL/6 mice; expression studies reveal Pla2g2a target genes and pathways.
Author:	Fijneman, Remond J A\|Bade, Lindsey K\|Peham, Johannes R\|van de Wiel, Mark A\|van Hinsbergh, Victor W M\|Meijer, Gerrit A\|O'Sullivan, Michael G\|Cormier, Robert T
PMID:	19759415

321.
Journal:	Orphanet J Rare Dis. 2009 Oct 12;4:22.
Title:	Familial adenomatous polyposis.
Author:	Half, Elizabeth\|Bercovich, Dani\|Rozen, Paul
PMID:	19822006

322.
Journal:	Cell Cycle. 2009 Nov 15;8(22):3684-7.
Title:	The role of mTORC1 pathway in intestinal tumorigenesis.
Author:	Fujishita, Teruaki\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	19855161

323.
Journal:	Adv Exp Med Biol. 2009;656:13-29.
Title:	Nuclear APC.
Author:	Neufeld, Kristi L
PMID:	19928349

324.
Journal:	Adv Exp Med Biol. 2009;656:85-106.
Title:	APC and its modifiers in colon cancer.
Author:	Kwong, Lawrence N\|Dove, William F
PMID:	19928355

325.
Journal:	Adv Exp Med Biol. 2009;656:107-18.
Title:	Tissue-specific tumour suppression by APC.
Author:	Sansom, Owen
PMID:	19928356

326.
Journal:	Neuro Endocrinol Lett. 2009;30 Suppl 1:25-8.
Title:	Polymorphisms in the adenomatous polyposis coli gene in Slovak families suspected of FAP.
Author:	Wachsmannova-Matelova, Lenka\|Stevurkova, Viola\|Adamcikova, Zuzana\|Holec, Vladimir\|Zajac, Vladimir
PMID:	20027139

327.
Journal:	J Cancer Res Clin Oncol. 2010 Apr;136(4):571-6.
Title:	Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer.
Author:	Zimmers, Teresa A\|Gutierrez, Juan C\|Koniaris, Leonidas G
PMID:	19784846

328.
Journal:	Genes Chromosomes Cancer. 2010 Feb;49(2):99-106.
Title:	Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients.
Author:	Thean, L F\|Loi, C\|Ho, K S\|Koh, P K\|Eu, K W\|Cheah, P Y
PMID:	19847890

329.
Journal:	Mech Dev. 2010 Jan-Feb;127(1-2):73-81.
Title:	Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling.
Author:	Varnat, Frederic\|Zacchetti, Giovanna\|Ruiz i Altaba, Ariel
PMID:	19861162

330.
Journal:	Gastroenterology. 2010 Mar;138(3):993-1002.e1.
Title:	An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.
Author:	Kucherlapati, Melanie H\|Lee, Kyeryoung\|Nguyen, Andrew A\|Clark, Alan B\|Hou, Harry Jr\|Rosulek, Andrew\|Li, Hua\|Yang, Kan\|Fan, Kunhua\|Lipkin, Martin\|Bronson, Roderick T\|Jelicks, Linda\|Kunkel, Thomas A\|Kucherlapati, Raju\|Edelmann, Winfried
PMID:	19931261

331.
Journal:	Gut. 2010 Apr;59(4):496-507.
Title:	Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons.
Author:	Zilberberg, Alona\|Lahav, Lital\|Rosin-Arbesfeld, Rina
PMID:	19951906

332.
Journal:	Oncogene. 2010 Mar 25;29(12):1857-64.
Title:	Complete deletion of Apc results in severe polyposis in mice.
Author:	Cheung, A F\|Carter, A M\|Kostova, K K\|Woodruff, J F\|Crowley, D\|Bronson, R T\|Haigis, K M\|Jacks, T
PMID:	20010873

333.
Journal:	BMC Cancer. 2010 Jan 5;10:3.
Title:	A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates.
Author:	Calabrese, Peter\|Shibata, Darryl
PMID:	20051132

334.
Journal:	Cell Physiol Biochem. 2010;25(2-3):271-8.
Title:	SGK1-dependent intestinal tumor growth in APC-deficient mice.
Author:	Wang, Kan\|Gu, Shuchen\|Nasir, Omaima\|Foller, Michael\|Ackermann, Teresa F\|Klingel, Karin\|Kandolf, Reinhard\|Kuhl, Dietmar\|Stournaras, Christos\|Lang, Florian
PMID:	20110688

335.
Journal:	Carcinogenesis. 2010 May;31(5):946-52.
Title:	A new conditional Apc-mutant mouse model for colorectal cancer.
Author:	Robanus-Maandag, Els C\|Koelink, Pim J\|Breukel, Cor\|Salvatori, Daniela C F\|Jagmohan-Changur, Shantie C\|Bosch, Cathy A J\|Verspaget, Hein W\|Devilee, Peter\|Fodde, Riccardo\|Smits, Ron
PMID:	20176656

336.
Journal:	PLoS One. 2010 Apr 2;5(4):e9994.
Title:	Topoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.
Author:	Wang, Yang\|Coffey, Robert J\|Osheroff, Neil\|Neufeld, Kristi L
PMID:	20368985

337.
Journal:	Steroids. 2010 Oct;75(10):665-75.
Title:	Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation.
Author:	Bellocq, Delphine\|Molina, Jerome\|Rathahao-Paris, Estelle\|Tache, Sylviane\|Pierre, Fabrice\|Paris, Alain
PMID:	20417221

338.
Journal:	PLoS One. 2010 Apr 28;5(4):e10371.
Title:	Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.
Author:	Labalette, Charlotte\|Nouet, Yann\|Levillayer, Florence\|Colnot, Sabine\|Chen, Ju\|Claude, Valere\|Huerre, Michel\|Perret, Christine\|Buendia, Marie-Annick\|Wei, Yu
PMID:	20442768

339.
Journal:	Scand J Gastroenterol. 2010 Nov;45(11):1320-8.
Title:	ERbeta expression in normal, adenomatous and carcinomatous tissues of patients with familial adenomatous polyposis.
Author:	Barone, Michele\|Scavo, Maria Principia\|Papagni, Samanta\|Piscitelli, Domenico\|Guido, Raffaella\|Di Lena, Maria\|Comelli, Maria Cristina\|Di Leo, Alfredo
PMID:	20446826

340.
Journal:	Neoplasia. 2010 May;12(5):415-24.
Title:	Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Author:	Kaur, Manjinder\|Velmurugan, Balaiya\|Tyagi, Alpna\|Agarwal, Chapla\|Singh, Rana P\|Agarwal, Rajesh
PMID:	20454513

341.
Journal:	Cell Cycle. 2010 Jun 15;9(12):2456-63. Epub 2010 Jun 15.
Title:	Increased angiogenesis in Cdk4(R24C/R24C):Apc(+/Min) intestinal tumors.
Author:	Abedin, Zahidur R\|Ma, Zhongjie\|Reddy, E Premkumar
PMID:	20603602

342.
Journal:	Clin Colorectal Cancer. 2010 Jul;9(3):168-76.
Title:	Novel methylation panel for the early detection of colorectal tumors in stool DNA.
Author:	Azuara, Daniel\|Rodriguez-Moranta, Francisco\|de Oca, Javier\|Soriano-Izquierdo, Antonio\|Mora, Josefina\|Guardiola, Jordi\|Biondo, Sebastiano\|Blanco, Ignacio\|Peinado, Miguel Angel\|Moreno, Victor\|Esteller, Manel\|Capella, Gabriel
PMID:	20643622

343.
Journal:	Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15145-50.
Title:	PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
Author:	Poulogiannis, George\|McIntyre, Rebecca E\|Dimitriadi, Maria\|Apps, John R\|Wilson, Catherine H\|Ichimura, Koichi\|Luo, Feijun\|Cantley, Lewis C\|Wyllie, Andrew H\|Adams, David J\|Arends, Mark J
PMID:	20696900

344.
Journal:	Dev Cell. 2010 Aug 17;19(2):259-69.
Title:	Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Author:	Ashton, Gabrielle H\|Morton, Jennifer P\|Myant, Kevin\|Phesse, Toby J\|Ridgway, Rachel A\|Marsh, Victoria\|Wilkins, Julie A\|Athineos, Dimitris\|Muncan, Vanesa\|Kemp, Richard\|Neufeld, Kristi\|Clevers, Hans\|Brunton, Valerie\|Winton, Douglas J\|Wang, Xiaoyan\|Sears, Ros
PMID:	20708588

345.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1128-38.
Title:	The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.
Author:	Lin, Songbai\|Lee, Sei-Jung\|Shim, Hyunsuk\|Chun, Jerold\|Yun, C Chris
PMID:	20724530

346.
Journal:	Cancer Res. 2010 Oct 15;70(20):8149-58.
Title:	Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.
Author:	Cole, Alicia M\|Myant, Kevin\|Reed, Karen R\|Ridgway, Rachel A\|Athineos, Dimitris\|Van den Brink, Gijs R\|Muncan, Vanesa\|Clevers, Hans\|Clarke, Alan R\|Sicinski, Peter\|Sansom, Owen J
PMID:	20736363

347.
Journal:	PLoS One. 2010 Sep 1;5(9).
Title:	Prediction and testing of biological networks underlying intestinal cancer.
Author:	Patel, Vishal N\|Bebek, Gurkan\|Mariadason, John M\|Wang, Donghai\|Augenlicht, Leonard H\|Chance, Mark R
PMID:	20824133

348.
Journal:	Mamm Genome. 2010 Oct;21(9-10):450-7.
Title:	The armadillo repeat domain of Apc suppresses intestinal tumorigenesis.
Author:	Crist, Richard C\|Roth, Jacquelyn J\|Baran, Amy A\|McEntee, Benjamin J\|Siracusa, Linda D\|Buchberg, Arthur M
PMID:	20886217

349.
Journal:	EMBO Mol Med. 2010 Nov;2(11):472-86.
Title:	p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.
Author:	Cole, Alicia M\|Ridgway, Rachel A\|Derkits, Sahra E\|Parry, Lee\|Barker, Nick\|Clevers, Hans\|Clarke, Alan R\|Sansom, Owen J
PMID:	20976827

350.
Journal:	PLoS Biol. 2010 Nov 16;8(11):e1000539.
Title:	The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis.
Author:	Mahmoudi, Tokameh\|Boj, Sylvia F\|Hatzis, Pantelis\|Li, Vivian S W\|Taouatas, Nadia\|Vries, Robert G J\|Teunissen, Hans\|Begthel, Harry\|Korving, Jeroen\|Mohammed, Shabaz\|Heck, Albert J R\|Clevers, Hans
PMID:	21103407

351.
Journal:	Cancers (Basel). 2010 Dec 29;3(1):91-105.
Title:	Detection of up to 65% of Precancerous Lesions of the Human Colon and Rectum by Mutation Analysis of APC, K-Ras, B-Raf and CTNNB1.
Author:	Schneider, Mandy\|Scholtka, Bettina\|Gottschalk, Uwe\|Faiss, Siegbert\|Schatz, Daniela\|Berghof-Jager, Kornelia\|Steinberg, Pablo
PMID:	24212608

352.
Journal:	Mol Carcinog. 2011 Jan;50(1):8-15.
Title:	Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors.
Author:	Meunier, Dominique\|Patra, Kalicharan\|Smits, Ron\|Hagebarth, Andrea\|Luttges, Angela\|Jaussi, Rolf\|Wieduwilt, Matthew J\|Quintanilla-Fend, Leticia\|Himmelbauer, Heinz\|Fodde, Riccardo\|Fundele, Reinald H
PMID:	21061267

353.
Journal:	Fam Cancer. 2011 Mar;10(1):21-6.
Title:	Mutation analysis of the APC gene in unrelated Korean patients with FAP: four novel mutations with unusual phenotype.
Author:	Han, Sung-Hee\|Ryu, Jae-Song\|Kim, Young-Jin\|Cho, Han-Ik\|Yang, Young-Ho\|Lee, Kyoung-Ryul
PMID:	21110124

354.
Journal:	Med Hypotheses. 2011 Feb;76(2):277-9.
Title:	SATB1 and colorectal cancer in Wnt/beta-catenin signaling: Is there a functional link?
Author:	Meng, Wen-Jian\|Yan, Hui\|Li, Yuan\|Zhou, Zong-Guang
PMID:	21122998

355.
Journal:	Gut. 2011 Feb;60(2):166-76.
Title:	Complex interplay between beta-catenin signalling and Notch effectors in intestinal tumorigenesis.
Author:	Peignon, Gregory\|Durand, Aurelie\|Cacheux, Wulfran\|Ayrault, Olivier\|Terris, Benoit\|Laurent-Puig, Pierre\|Shroyer, Noah F\|Van Seuningen, Isabelle\|Honjo, Tasuku\|Perret, Christine\|Romagnolo, Beatrice
PMID:	21205878

356.
Journal:	Cancer Res. 2011 Jan 15;71(2):593-602.
Title:	Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.
Author:	Aoki, Koji\|Kakizaki, Fumihiko\|Sakashita, Hiromi\|Manabe, Toshiaki\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	21224344

357.
Journal:	Curr Cancer Drug Targets. 2011 May;11(4):451-64.
Title:	Cytokines, inflammation and colon cancer.
Author:	Klampfer, Lidija
PMID:	21247378

358.
Journal:	Oncogene. 2011 Jun 9;30(23):2659-69.
Title:	Loss of a single Hic1 allele accelerates polyp formation in Apc(Delta716) mice.
Author:	Mohammad, H P\|Zhang, W\|Prevas, H S\|Leadem, B R\|Zhang, M\|Herman, J G\|Hooker, C M\|Watkins, D N\|Karim, B\|Huso, D L\|Baylin, S B
PMID:	21297660

359.
Journal:	Pathol Oncol Res. 2011 Sep;17(3):657-61.
Title:	Detection of APC gene deletions in colorectal malignancies using quantitative PCR in a Chinese population.
Author:	Fang, Zhengyu\|Xiong, Yi\|Li, Jiana\|Liu, Li\|Li, Manhui\|Zhang, Wei\|Shi, Lei\|Wan, Jun
PMID:	21359685

360.
Journal:	J Proteome Res. 2011 May 6;10(5):2129-39.
Title:	Proteins and an inflammatory network expressed in colon tumors.
Author:	Zhu, Wenhong\|Fang, Changming\|Gramatikoff, Kosi\|Niemeyer, Christina C\|Smith, Jeffrey W
PMID:	21366352

361.
Journal:	Clin Exp Metastasis. 2011 Jun;28(5):427-35.
Title:	Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors.
Author:	Goranova, Teodora Evgenieva\|Ohue, Masayuki\|Shimoharu, Yutaro\|Kato, Kikuya
PMID:	21380628

362.
Journal:	Cell Cycle. 2011 Apr 1;10(7):1092-9.
Title:	Identification of Mom12 and Mom13, two novel modifier loci of Apc (Min) -mediated intestinal tumorigenesis.
Author:	Crist, Richard C\|Roth, Jacquelyn J\|Lisanti, Michael P\|Siracusa, Linda D\|Buchberg, Arthur M
PMID:	21386660

363.
Journal:	Mol Cancer Ther. 2011 Apr;10(4):648-57.
Title:	Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer.
Author:	Symolon, Holly\|Bushnev, Anatoliy\|Peng, Qiong\|Ramaraju, Harsha\|Mays, Suzanne G\|Allegood, Jeremy C\|Pruett, Sarah T\|Sullards, M Cameron\|Dillehay, Dirck L\|Liotta, Dennis C\|Merrill, Alfred H Jr
PMID:	21398423

364.
Journal:	Oncol Rep. 2011 May;25(5):1195-201.
Title:	Preclinical in vitro models from genetically engineered mice for breast and colon cancer (Review).
Author:	Telang, Nitin\|Katdare, Meena
PMID:	21399881

365.
Journal:	Cancer Genomics Proteomics. 2011 May-Jun;8(3):149-55.
Title:	Analysis of APC allelic imbalance/loss of heterozygosity and APC protein expression in cutaneous squamous cell carcinomas.
Author:	Gray, Sarah E\|Kay, Elaine W\|Leader, Mary\|Mabruk, Mohamed
PMID:	21518821

366.
Journal:	Fam Cancer. 2011 Jun;10(2):309-13.
Title:	A new phenotypic manifestation of familial adenomatous polyposis.
Author:	Edelstein, Daniel L\|Giardiello, Francis M\|Basiri, Ali\|Hylind, Linda M\|Romans, Katharine\|Axilbund, Jennifer E\|Cruz-Correa, Marcia\|Ramella-Roman, Jessica C
PMID:	21547505

367.
Journal:	Int J Biochem Cell Biol. 2011 Sep;43(9):1354-64.
Title:	Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress.
Author:	Brocardo, Mariana G\|Borowiec, James A\|Henderson, Beric R
PMID:	21664290

368.
Journal:	Carcinogenesis. 2011 Sep;32(9):1396-402.
Title:	Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice.
Author:	Raufman, Jean-Pierre\|Shant, Jasleen\|Xie, Guofeng\|Cheng, Kunrong\|Gao, Xue-Min\|Shiu, Brian\|Shah, Nirish\|Drachenberg, Cinthia B\|Heath, Jonathon\|Wess, Jurgen\|Khurana, Sandeep
PMID:	21705482

369.
Journal:	Gastroenterology. 2011 Nov;141(5):1762-72.
Title:	Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
Author:	Sato, Toshiro\|Stange, Daniel E\|Ferrante, Marc\|Vries, Robert G J\|Van Es, Johan H\|Van den Brink, Stieneke\|Van Houdt, Winan J\|Pronk, Apollo\|Van Gorp, Joost\|Siersema, Peter D\|Clevers, Hans
PMID:	21889923

370.
Journal:	PLoS One. 2011;6(8):e24114.
Title:	Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.
Author:	Vasovcak, Peter\|Pavlikova, Kristyna\|Sedlacek, Zdenek\|Skapa, Petr\|Kouda, Martin\|Hoch, Jiri\|Krepelova, Anna
PMID:	21901162

371.
Journal:	Arch Biochem Biophys. 2011 Nov;515(1-2):64-71.
Title:	Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models.
Author:	Irving, Amy A\|Halberg, Richard B\|Albrecht, Dawn M\|Plum, Lori A\|Krentz, Kathleen J\|Clipson, Linda\|Drinkwater, Norman\|Amos-Landgraf, James M\|Dove, William F\|DeLuca, Hector F
PMID:	21907701

372.
Journal:	Chem Res Toxicol. 2011 Nov 21;24(11):1984-93.
Title:	4-Hydroxy-2(E)-nonenal metabolism differs in Apc(+/+) cells and in Apc(Min/+) cells: it may explain colon cancer promotion by heme iron.
Author:	Baradat, Maryse\|Jouanin, Isabelle\|Dalleau, Sabine\|Tache, Sylviane\|Gieules, Mathilde\|Debrauwer, Laurent\|Canlet, Cecile\|Huc, Laurence\|Dupuy, Jacques\|Pierre, Fabrice H F\|Gueraud, Francoise
PMID:	21967605

373.
Journal:	Structure. 2011 Oct 12;19(10):1496-508.
Title:	Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68.
Author:	Morishita, Ella Czarina\|Murayama, Kazutaka\|Kato-Murayama, Miyuki\|Ishizuka-Katsura, Yoshiko\|Tomabechi, Yuri\|Hayashi, Tomoatsu\|Terada, Takaho\|Handa, Noriko\|Shirouzu, Mikako\|Akiyama, Tetsu\|Yokoyama, Shigeyuki
PMID:	22000517

374.
Journal:	Acta Gastroenterol Belg. 2011 Sep;74(3):421-6.
Title:	The genetics of familial adenomatous polyposis (FAP) and MutYH-associated polyposis (MAP).
Author:	Claes, Kathleen\|Dahan, Karin\|Tejpar, S\|De Paepe, Anne\|Bonduelle, Maryse\|Abramowicz, Marc\|Verellen, Christine\|Franchimont, Denis\|Van Cutsem, Eric\|Kartheuser, Alex
PMID:	22103048

375.
Journal:	Cell Commun Adhes. 2011 Dec;18(6):133-43.
Title:	E-cadherin and the cytoskeletal network in colorectal cancer development and metastasis.
Author:	Buda, Andrea\|Pignatelli, Massimo
PMID:	22176698

376.
Journal:	Cell Res. 2012 Feb;22(2):372-86.
Title:	Structural basis for the recognition of Asef by adenomatous polyposis coli.
Author:	Zhang, Zhenyi\|Chen, Leyi\|Gao, Lei\|Lin, Kui\|Zhu, Liang\|Lu, Yang\|Shi, Xiaoshan\|Gao, Yuan\|Zhou, Jing\|Xu, Ping\|Zhang, Jian\|Wu, Geng
PMID:	21788986

377.
Journal:	Oncogene. 2012 Apr 19;31(16):2028-38.
Title:	Different phenotypic consequences of simultaneous versus stepwise Apc loss.
Author:	Fischer, J M\|Miller, A J\|Shibata, D\|Liskay, R M
PMID:	21892206

378.
Journal:	Gastroenterology. 2012 Jan;142(1):71-77.e1.
Title:	Increased variance in germline allele-specific expression of APC associates with colorectal cancer.
Author:	Curia, Maria Cristina\|De Iure, Sabrina\|De Lellis, Laura\|Veschi, Serena\|Mammarella, Sandra\|White, Marquitta J\|Bartlett, Jacquelaine\|Di Iorio, Angelo\|Amatetti, Cristina\|Lombardo, Marco\|Di Gregorio, Patrizia\|Battista, Pasquale\|Mariani-Costantini, Renato\|Will
PMID:	21995949

379.
Journal:	Oncogene. 2012 May 10;31(19):2423-37.
Title:	A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.
Author:	Zeineldin, M\|Cunningham, J\|McGuinness, W\|Alltizer, P\|Cowley, B\|Blanchat, B\|Xu, W\|Pinson, D\|Neufeld, K L
PMID:	21996741

380.
Journal:	Int J Cancer. 2012 Sep 15;131(6):1435-44.
Title:	Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.
Author:	Li, Shiwang\|Ghaleb, Amr M\|He, Jing\|Bughani, Usha\|Bialkowska, Agnieszka B\|Yang, Vincent W\|Joshi, Harish C
PMID:	22052467

381.
Journal:	J Gastrointest Surg. 2012 Feb;16(2):389-93.
Title:	Genetic deletion of 5-lipoxygenase increases tumor-infiltrating macrophages in Apc(Delta468) mice.
Author:	Cheon, Eric C\|Strouch, Matthew J\|Krantz, Seth B\|Heiferman, Michael J\|Bentrem, David J
PMID:	22072302

382.
Journal:	Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2060-5.
Title:	Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms.
Author:	Amos-Landgraf, James M\|Irving, Amy A\|Hartman, Cory\|Hunter, Anthony\|Laube, Brianna\|Chen, Xiaodi\|Clipson, Linda\|Newton, Michael A\|Dove, William F
PMID:	22308460

383.
Journal:	Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3047-52.
Title:	Essential requirement for beta-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.
Author:	Bonnans, Caroline\|Flaceliere, Maud\|Grillet, Fanny\|Dantec, Christelle\|Desvignes, Jean-Pierre\|Pannequin, Julie\|Severac, Dany\|Dubois, Emeric\|Bibeau, Frederic\|Escriou, Virginie\|Crespy, Philippe\|Journot, Laurent\|Hollande, Frederic\|Joubert, Dominique
PMID:	22315403

384.
Journal:	Neoplasia. 2012 Feb;14(2):159-68.
Title:	Chemopreventive effects of RXR-selective rexinoid bexarotene on intestinal neoplasia of Apc(Min/+) mice.
Author:	Janakiram, Naveena B\|Mohammed, Altaf\|Qian, Li\|Choi, Chang-In\|Steele, Vernon E\|Rao, Chinthalapally V
PMID:	22431924

385.
Journal:	Lancet Oncol. 2012 Jun;13(6):598-606.
Title:	Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study.
Author:	Kloor, Matthias\|Huth, Cathrin\|Voigt, Anita Y\|Benner, Axel\|Schirmacher, Peter\|von Knebel Doeberitz, Magnus\|Blaker, Hendrik
PMID:	22552011

386.
Journal:	Mutat Res Rev Mutat Res. 2012 Jul-Sep;751(1):64-75.
Title:	The influence of folate and methionine on intestinal tumour development in the Apc(Min/+) mouse model.
Author:	Teh, Arnida Hani\|Symonds, Erin\|Bull, Caroline\|Clifton, Peter\|Fenech, Michael
PMID:	22627043

387.
Journal:	Carcinogenesis. 2012 Aug;33(8):1589-97.
Title:	Identification of five novel modifier loci of Apc(Min) harbored in the BXH14 recombinant inbred strain.
Author:	Nnadi, Stephanie C\|Watson, Rayneisha\|Innocent, Julie\|Gonye, Gregory E\|Buchberg, Arthur M\|Siracusa, Linda D
PMID:	22637734

388.
Journal:	Fam Cancer. 2012 Sep;11(3):529-33.
Title:	Hepatoblastoma in two siblings and familial adenomatous polyposis: causal nexus or coincidence?
Author:	Evers, Christina\|Gaspar, Harald\|Kloor, Matthias\|Bozukova, Gergana\|Kadmon, Martina\|Keller, Monika\|Sutter, Christian\|Moog, Ute
PMID:	22692730

389.
Journal:	Electrophoresis. 2012 Jul;33(12):1873-80.
Title:	Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Author:	Lim, Justin W E\|Mathias, Rommel A\|Kapp, Eugene A\|Layton, Meredith J\|Faux, Maree C\|Burgess, Antony W\|Ji, Hong\|Simpson, Richard J
PMID:	22740476

390.
Journal:	Obstet Gynecol. 2012 Aug;120(2 Pt 2):500-3.
Title:	Perinatal detection of familial adenomatous polyposis.
Author:	Birsner, Meredith L\|Hoover-Fong, Julie\|Bytyci Telegrafi, Aida\|Hueppchen, Nancy A
PMID:	22825279

391.
Journal:	J Cell Biol. 2012 Aug 6;198(3):331-41.
Title:	The tumor suppressor Apc controls planar cell polarities central to gut homeostasis.
Author:	Bellis, Julien\|Duluc, Isabelle\|Romagnolo, Beatrice\|Perret, Christine\|Faux, Maree C\|Dujardin, Denis\|Formstone, Caroline\|Lightowler, Sally\|Ramsay, Robert G\|Freund, Jean-Noel\|De Mey, Jan R
PMID:	22851318

392.
Journal:	Gastroenterology. 2012 Nov;143(5):1173-1175.e7.
Title:	A porcine model of familial adenomatous polyposis.
Author:	Flisikowska, Tatiana\|Merkl, Claudia\|Landmann, Martina\|Eser, Stefan\|Rezaei, Nousin\|Cui, Xinxin\|Kurome, Mayuko\|Zakhartchenko, Valeri\|Kessler, Barbara\|Wieland, Hagen\|Rottmann, Oswald\|Schmid, Roland M\|Schneider, Gunter\|Kind, Alexander\|Wolf, Eckhard\|Saur, Diet
PMID:	22864254

393.
Journal:	J Pathol. 2012 Nov;228(3):405-15.
Title:	Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk study.
Author:	Gay, Laura J\|Mitrou, Panagiota N\|Keen, Jennifer\|Bowman, Richard\|Naguib, Adam\|Cooke, James\|Kuhnle, Gunter G\|Burns, Philip A\|Luben, Robert\|Lentjes, Marleen\|Khaw, Kay-Tee\|Ball, Richard Y\|Ibrahim, Ashraf Ek\|Arends, Mark J
PMID:	22864938

394.
Journal:	Cell Rep. 2012 Aug 30;2(2):270-82.
Title:	Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo.
Author:	Radulescu, Sorina\|Brookes, Matthew J\|Salgueiro, Pedro\|Ridgway, Rachel A\|McGhee, Ewan\|Anderson, Kurt\|Ford, Samuel J\|Stones, Daniel H\|Iqbal, Tariq H\|Tselepis, Chris\|Sansom, Owen J
PMID:	22884366

395.
Journal:	BMC Cancer. 2012 Oct 3;12:448.
Title:	Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay.
Author:	Yoshimi, Kazuto\|Hashimoto, Takao\|Niwa, Yusuke\|Hata, Kazuya\|Serikawa, Tadao\|Tanaka, Takuji\|Kuramoto, Takashi
PMID:	23031214

396.
Journal:	S Afr Med J. 2012 Sep 10;102(11 Pt 2):888-9.
Title:	Lessons from the hepatoblastoma-familial polyposis connection.
Author:	Moore, S W\|Tshifularo, N\|Grobbelaar, J
PMID:	23116752

397.
Journal:	Zhonghua Zhong Liu Za Zhi. 2012 Sep;34(9):674-8.
Title:	[Expression of Wnt5a, APC, beta-catenin and their clinical significance in human colorectal adenocarcinoma].
Author:	Cao, Yong-cheng\|Yang, Fan\|Liu, Xiao-hong\|Xin, Xuan\|Wang, Cui-cui\|Geng, Ming
PMID:	23159080

398.
Journal:	Development. 2012 Dec;139(24):4524-35.
Title:	Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut.
Author:	Cordero, Julia B\|Stefanatos, Rhoda K\|Myant, Kevin\|Vidal, Marcos\|Sansom, Owen J
PMID:	23172913

399.
Journal:	Nutr Res Pract. 2012 Oct;6(5):396-404.
Title:	Inhibitory effects of calcium against intestinal cancer in human colon cancer cells and Apc(Min/+) mice.
Author:	Ju, Jihyeung\|Kwak, Youngeun\|Hao, Xingpei\|Yang, Chung S
PMID:	23198018

400.
Journal:	Asian Pac J Cancer Prev. 2012;13(10):5101-4.
Title:	Colon cancer prevention by detection of APC gene mutation in a family with attenuated familial adenomatous polyposis.
Author:	Poovorawan, Kittiyod\|Suksawatamnuay, Sirinporn\|Sahakitrungruang, Chucheep\|Treeprasertsuk, Sombat\|Wisedopas, Naruemon\|Komolmit, Piyawat\|Poovorawan, Yong
PMID:	23244118

401.
Journal:	Int J Colorectal Dis. 2013 Jun;28(6):865-72.
Title:	Recurrent desmoids determine outcome in patients with Gardner syndrome: a cohort study of three generations of an APC mutation-positive family across 30 years.
Author:	Turina, Matthias\|Pavlik, Caroline Marianne\|Heinimann, Karl\|Behrensmeier, Frank\|Simmen, Hans-Peter
PMID:	23114473

402.
Journal:	Biochim Biophys Acta. 2013 Aug;1836(1):80-9.
Title:	More than two decades of Apc modeling in rodents.
Author:	Zeineldin, Maged\|Neufeld, Kristi L
PMID:	23333833

403.
Journal:	Mol Imaging. 2013 Jan-Feb;12(1):59-66.
Title:	Quantitative magnetic resonance imaging in the transgenic APC(Delta468) mouse model of hereditary colon cancer.
Author:	Zhang, Zhuoli\|Li, Weiguo\|Blatner, Nichole R\|Dennis, Kristen L\|Procissi, Daniel\|Khazaie, Khashayarsha\|Larson, Andrew C
PMID:	23348792

404.
Journal:	Am J Pathol. 2013 Apr;182(4):1263-74.
Title:	Tumor suppressor APC protein is essential in mucosal repair from colonic inflammation through angiogenesis.
Author:	Yoshimi, Kazuto\|Tanaka, Takuji\|Serikawa, Tadao\|Kuramoto, Takashi
PMID:	23395091

405.
Journal:	Med Mol Morphol. 2013 Sep;46(3):166-71.
Title:	Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors.
Author:	Kamatani, Akemi\|Nakagawa, Yoshihito\|Akao, Yukihiro\|Maruyama, Naoko\|Nagasaka, Mitsuo\|Shibata, Tomoyuki\|Tahara, Tomomitsu\|Hirata, Ichiro
PMID:	23397547

406.
Journal:	PLoS One. 2013;8(3):e58540.
Title:	Protein kinase C delta negatively modulates canonical Wnt pathway and cell proliferation in colon tumor cell lines.
Author:	Hernandez-Maqueda, Jose G\|Luna-Ulloa, Luis Bernardo\|Santoyo-Ramos, Paula\|Castaneda-Patlan, M Cristina\|Robles-Flores, Martha
PMID:	23520519

407.
Journal:	Cancer Res. 2013 Apr 15;73(8):2389-99.
Title:	Understanding phenotypic variation in rodent models with germline Apc mutations.
Author:	Zeineldin, Maged\|Neufeld, Kristi L
PMID:	23580574

408.
Journal:	Carcinogenesis. 2013 Sep;34(9):2109-18.
Title:	Deficiency of caveolin-1 in Apc(min/+) mice promotes colorectal tumorigenesis.
Author:	Friedrich, Teresa\|Richter, Birgit\|Gaiser, Timo\|Weiss, Christel\|Janssen, Klaus-Peter\|Einwachter, Henrik\|Schmid, Roland M\|Ebert, Matthias P A\|Burgermeister, Elke
PMID:	23640045

409.
Journal:	PLoS One. 2013 Jun 18;8(6):e66165.
Title:	Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer.
Author:	Schee, Kristina\|Lorenz, Susanne\|Worren, Merete Molton\|Gunther, Clara-Cecilie\|Holden, Marit\|Hovig, Eivind\|Fodstad, Oystein\|Meza-Zepeda, Leonardo A\|Flatmark, Kjersti
PMID:	23824282

410.
Journal:	Methods Mol Biol. 2013;1012:237-48.
Title:	Methods to assess Myc function in intestinal homeostasis, regeneration, and tumorigenesis.
Author:	Huels, David J\|Cammareri, Patrizia\|Ridgway, Rachel A\|Medema, Jan P\|Sansom, Owen J
PMID:	24006069

411.
Journal:	Mol Biol Rep. 2013 Oct;40(10):5921-9.
Title:	Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.
Author:	Polakova Vymetalkova, Veronika\|Vannucci, Luca\|Korenkova, Vlasta\|Prochazka, Pavel\|Slyskova, Jana\|Vodickova, Ludmila\|Rusnakova, Vendula\|Bielik, Ludovit\|Burocziova, Monika\|Rossmann, Pavel\|Vodicka, Pavel
PMID:	24065530

412.
Journal:	Mol Carcinog. 2014 Jan;53(1):77-84.
Title:	Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation.
Author:	Cheung, Ka Lung\|Lee, Jong Hun\|Khor, Tin Oo\|Wu, Tien-Yuan\|Li, Guang Xun\|Chan, Jefferson\|Yang, Chung S\|Kong, Ah-Ng Tony
PMID:	22911891

413.
Journal:	Carcinogenesis. 2014 Jan;35(1):237-46.
Title:	Occult progression by Apc-deficient intestinal crypts as a target for chemoprevention.
Author:	Fischer, Jared M\|Schepers, Arnout G\|Clevers, Hans\|Shibata, Darryl\|Liskay, R Michael
PMID:	23996931

414.
Journal:	Dis Model Mech. 2014 Jan;7(1):63-71.
Title:	Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
Author:	Valvezan, Alexander J\|Huang, Jian\|Lengner, Christopher J\|Pack, Michael\|Klein, Peter S
PMID:	24092877

415.
Journal:	Eur J Hum Genet. 2014 Jun;22(6):833-6.
Title:	A novel indel in exon 9 of APC upregulates a 'skip exon 9' isoform and causes very severe familial adenomatous polyposis.
Author:	Cheah, Peh Yean\|Wong, Yu Hui\|Koh, Poh Koon\|Loi, Carol\|Chew, Min Hoe\|Tang, Choong Leong
PMID:	24169521

416.
Journal:	Cancer Prev Res (Phila). 2014 Jan;7(1):105-13.
Title:	Dynamic tumor growth patterns in a novel murine model of colorectal cancer.
Author:	Paul Olson, Terrah J\|Hadac, Jamie N\|Sievers, Chelsie K\|Leystra, Alyssa A\|Deming, Dustin A\|Zahm, Christopher D\|Albrecht, Dawn M\|Nomura, Alice\|Nettekoven, Laura A\|Plesh, Lauren K\|Clipson, Linda\|Sullivan, Ruth\|Newton, Michael A\|Schelman, William R\|Halberg, R
PMID:	24196829

417.
Journal:	FEBS J. 2014 Feb;281(3):787-801.
Title:	Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-beta-catenin signalling.
Author:	Brauburger, Katharina\|Akyildiz, Senem\|Ruppert, Jan G\|Graeb, Michael\|Bernkopf, Dominic B\|Hadjihannas, Michel V\|Behrens, Jurgen
PMID:	24251807

418.
Journal:	Cell J. 2014 Feb 3;16(1):17-24. Epub 2014 Feb 3.
Title:	A unique profile of adenomatous polyposis coli gene mutations in Iranian patients suffering sporadic colorectal cancer.
Author:	Hasanpour, Mojtaba\|Galehdari, Hamid\|Masjedizadeh, Abdolrahim\|Ajami, Naser
PMID:	24518971

419.
Journal:	Eur J Hum Genet. 2014 Nov;22(11):1330-3.
Title:	Attenuated familial adenomatous polyposis manifests as autosomal dominant late-onset colorectal cancer.
Author:	Ibrahim, Abdulla\|Barnes, Daniel R\|Dunlop, Jacqueline\|Barrowdale, Daniel\|Antoniou, Antonis C\|Berg, Jonathan N
PMID:	24549056

420.
Journal:	J Clin Pathol. 2014 Jun;67(6):491-8.
Title:	Prevalence and molecular characterisation of the sessile serrated adenoma in a subset of the Chinese population.
Author:	Qiu, Ye\|Fu, Xiangsheng\|Zhang, Wei\|Xu, Yong\|Xiao, Lanyue\|Chen, Xia\|Shi, Lei\|Zhou, Xian\|Xia, Guodong\|Peng, Yan\|Deng, Mingming
PMID:	24570042

421.
Journal:	Biochem Biophys Res Commun. 2014 Apr 4;446(2):460-4.
Title:	Aspirin augments the expression of Adenomatous Polyposis Coli protein by suppression of IKKbeta.
Author:	Ashida, Noboru\|Kishihata, Masako\|Tien, Dat Nguyen\|Kamei, Kaeko\|Kimura, Takeshi\|Yokode, Masayuki
PMID:	24613833

422.
Journal:	Int J Cancer. 2014 Oct 15;135(8):1800-11.
Title:	beta-catenin regulates NF-kappaB activity via TNFRSF19 in colorectal cancer cells.
Author:	Schon, Simon\|Flierman, Isabelle\|Ofner, Andrea\|Stahringer, Anika\|Holdt, Lesca Miriam\|Kolligs, Frank T\|Herbst, Andreas
PMID:	24623448

423.
Journal:	Cancer Lett. 2014 Jun 1;347(2):191-5.
Title:	Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
Author:	Byun, Alexander J\|Hung, Kenneth E\|Fleet, James C\|Bronson, Roderick T\|Mason, Joel B\|Garcia, Paloma E\|Crott, Jimmy W
PMID:	24632531

424.
Journal:	Fam Cancer. 2014 Sep;13(3):361-8.
Title:	Two Chinese pedigrees for adenomatous polyposis coli: new mutations at codon 1309 and predisposition to phenotypic variations.
Author:	Liao, Dai-Xiang\|Li, Bing\|Du, Xue-Mei\|Yu, Jun-Hui\|Chang, Hong\|Wu, Zhi-Qiang\|Hao, Hao-Jie\|Wang, You-Xin\|Han, Wei-Dong\|Cheng, Shu-Jun\|Luo, Cheng-Hua
PMID:	24664542

425.
Journal:	Comp Med. 2014 Apr;64(2):128-34.
Title:	A simple, quantitative method using alginate gel to determine rat colonic tumor volume in vivo.
Author:	Irving, Amy A\|Young, Lindsay B\|Pleiman, Jennifer K\|Konrath, Michael J\|Marzella, Blake\|Nonte, Michael\|Cacciatore, Justin\|Ford, Madeline R\|Clipson, Linda\|Amos-Landgraf, James M\|Dove, William F
PMID:	24674588

426.
Journal:	J Clin Biochem Nutr. 2014 Mar;54(2):95-101.
Title:	Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice.
Author:	Shimizu, Satomi\|Fujii, Gen\|Takahashi, Mami\|Nakanishi, Ruri\|Komiya, Masami\|Shimura, Misato\|Noma, Nobuharu\|Onuma, Wakana\|Terasaki, Masaru\|Yano, Tomohiro\|Mutoh, Michihiro
PMID:	24688218

427.
Journal:	Cell Res. 2014 Jun;24(6):701-12.
Title:	Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing.
Author:	Yu, Chang\|Yu, Jun\|Yao, Xiaotian\|Wu, William K K\|Lu, Youyong\|Tang, Senwei\|Li, Xiangchun\|Bao, Li\|Li, Xiaoxing\|Hou, Yong\|Wu, Renhua\|Jian, Min\|Chen, Ruoyan\|Zhang, Fan\|Xu, Lixia\|Fan, Fan\|He, Jun\|Liang, Qiaoyi\|Wang, Hongyi\|Hu, Xueda\|He, Minghui\|Zhang, Xiang\|Zhe
PMID:	24699064

428.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1;307(1):G16-23.
Title:	Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
Author:	Powell, Anne E\|Vlacich, Gregory\|Zhao, Zhen-Yang\|McKinley, Eliot T\|Washington, M Kay\|Manning, H Charles\|Coffey, Robert J
PMID:	24833705

429.
Journal:	Genetics. 2014 Aug;197(4):1285-302.
Title:	Testing models of the APC tumor suppressor/beta-catenin interaction reshapes our view of the destruction complex in Wnt signaling.
Author:	Yamulla, Robert J\|Kane, Eric G\|Moody, Alexandra E\|Politi, Kristin A\|Lock, Nicole E\|Foley, Andrew V A\|Roberts, David M
PMID:	24931405

430.
Journal:	Oncol Lett. 2014 Jun;7(6):1761-1766.
Title:	'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patients.
Author:	Fang, Weijia\|Radovich, Milan\|Zheng, Yulong\|Fu, Cai-Yun\|Zhao, Peng\|Mao, Chengyu\|Zheng, Yi\|Zheng, Shusen
PMID:	24932229

431.
Journal:	Int J Clin Exp Pathol. 2014 May 15;7(6):3255-63. eCollection 2014.
Title:	Expression of APC protein during tongue malignant transformation in galectin-3-deficient mice challenged by the carcinogen 4-nitroquniline-n-oxide.
Author:	de Souza, Marcus Vinicius Rodrigues\|Servato, Joao Paulo Silva\|Loyola, Adriano Mota\|Cardoso, Sergio Vitorino\|Chammas, Roger\|Liu, Fu-Tong\|Silva, Marcelo Jose Barbosa\|de Faria, Paulo Rogerio
PMID:	25031746

432.
Journal:	Fam Cancer. 2014 Dec;13(4):563-71.
Title:	The secondary bile acid, deoxycholate accelerates intestinal adenoma-adenocarcinoma sequence in Apc (min/+) mice through enhancing Wnt signaling.
Author:	Cao, Hailong\|Luo, Shenhui\|Xu, Mengque\|Zhang, Yujie\|Song, Shuli\|Wang, Shan\|Kong, Xinyue\|He, Nana\|Cao, Xiaocang\|Yan, Fang\|Wang, Bangmao
PMID:	25106466

433.
Journal:	Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9.
Title:	The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.
Author:	Ivancic, Melanie M\|Irving, Amy A\|Jonakin, Kelli G\|Dove, William F\|Sussman, Michael R
PMID:	25200834

434.
Journal:	Oncotarget. 2014 Oct 15;5(19):9269-80.
Title:	DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition.
Author:	Chandrakesan, Parthasarathy\|Weygant, Nathaniel\|May, Randal\|Qu, Dongfeng\|Chinthalapally, Harisha R\|Sureban, Sripathi M\|Ali, Naushad\|Lightfoot, Stan A\|Umar, Shahid\|Houchen, Courtney W
PMID:	25211188

435.
Journal:	Rev Med Inst Mex Seguro Soc. 2014 Sep-Oct;52(5):594-7.
Title:	[Proctocolectomy with ileoanal anastomoses and desmoid tumor treated with resection. One case of familial adenomatous polyposis].
Author:	Villalon-Lopez, Jose Sebastian\|Souto-del Bosque, Rosalia\|Mendez-Sashida, Pedro Gonzalo
PMID:	25301135

436.
Journal:	Front Oncol. 2014 Nov 14;4:323.
Title:	Prom1 function in development, intestinal inflammation, and intestinal tumorigenesis.
Author:	Karim, Baktiar O\|Rhee, Ki-Jong\|Liu, Guosheng\|Yun, Kyuson\|Brant, Steven R
PMID:	25452936

437.
Journal:	Int J Cancer. 2015 Jan 15;136(2):271-7.
Title:	UV exposure inhibits intestinal tumor growth and progression to malignancy in intestine-specific Apc mutant mice kept on low vitamin D diet.
Author:	Rebel, Heggert\|der Spek, Celia Dingemanse-van\|Salvatori, Daniela\|van Leeuwen, Johannes P T M\|Robanus-Maandag, Els C\|de Gruijl, Frank R
PMID:	24890436

438.
Journal:	Mol Carcinog. 2015 Nov;54(11):1264-74.
Title:	Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of beta-catenin/Ctnnb1 as the driver gene for the carcinogenesis.
Author:	Wang, Hong\|Zhou, Hong\|Liu, Anna\|Guo, Xiangyi\|Yang, Chung S
PMID:	25131582

439.
Journal:	Eur J Cancer Prev. 2015 May;24(3):180-7.
Title:	Utility of Apc-mutant rats with a colitis-associated colon carcinogenesis model for chemoprevention studies.
Author:	Kochi, Takahiro\|Shimizu, Masahito\|Shirakami, Yohei\|Yoshimi, Kazuto\|Kuramoto, Takashi\|Tanaka, Takuji\|Moriwaki, Hisataka
PMID:	25222193

440.
Journal:	Int J Cancer. 2015 Mar 15;136(6):E488-95.
Title:	Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc.
Author:	Femia, Angelo Pietro\|Luceri, Cristina\|Soares, Paulo Victoria\|Lodovici, Maura\|Caderni, Giovanna
PMID:	25257656

441.
Journal:	Biochem Biophys Res Commun. 2015 May 29;461(2):249-53.
Title:	Inactivation of Itf2 promotes intestinal tumorigenesis in Apc(Min/+) mice.
Author:	Grill, Jessica I\|Herbst, Andreas\|Brandl, Lydia\|Kong, Lixia\|Schneider, Marlon R\|Kirchner, Thomas\|Wolf, Eckhard\|Kolligs, Frank T
PMID:	25869068

442.
Journal:	BMC Cancer. 2015 Mar 8;15:110.
Title:	Hunk/Mak-v is a negative regulator of intestinal cell proliferation.
Author:	Reed, Karen R\|Korobko, Igor V\|Ninkina, Natalia\|Korobko, Elena V\|Hopkins, Ben R\|Platt, James L\|Buchman, Vladimir\|Clarke, Alan R
PMID:	25881306

443.
Journal:	Theranostics. 2015 Apr 1;5(7):724-32.
Title:	Longitudinal Tracing of Spontaneous Regression and Anti-angiogenic Response of Individual Microadenomas during Colon Tumorigenesis.
Author:	Choi, Jin Woo\|Kim, Pilhan\|Kim, Jun Ki\|Kim, Yi Rang\|Fukumura, Dai\|Yun, Seok Hyun
PMID:	25897337

444.
Journal:	Int J Cancer. 2015 Nov 1;137(9):2270-3.
Title:	Apc-driven colon carcinogenesis in Pirc rat is strongly reduced by polyethylene glycol.
Author:	Femia, Angelo Pietro\|Becherucci, Caterina\|Crucitta, Stefania\|Caderni, Giovanna
PMID:	25912754

445.
Journal:	Mol Oncol. 2015 Aug;9(7):1406-20.
Title:	Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Author:	Lan, Lan\|Appelman, Carl\|Smith, Amber R\|Yu, Jia\|Larsen, Sarah\|Marquez, Rebecca T\|Liu, Hao\|Wu, Xiaoqing\|Gao, Philip\|Roy, Anuradha\|Anbanandam, Asokan\|Gowthaman, Ragul\|Karanicolas, John\|De Guzman, Roberto N\|Rogers, Steven\|Aube, Jeffrey\|Ji, Min\|Cohen, Robert S
PMID:	25933687

446.
Journal:	Mol Cancer Res. 2015 Aug;13(8):1185-96.
Title:	Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis.
Author:	Cheasley, Dane\|Pereira, Lloyd\|Sampurno, Shienny\|Sieber, Oliver\|Jorissen, Robert\|Xu, Huiling\|Germann, Markus\|Yuqian, Yan\|Ramsay, Robert G\|Malaterre, Jordane
PMID:	25934694

447.
Journal:	PLoS One. 2015 May 14;10(5):e0126670.
Title:	Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.
Author:	Kim, Richard\|Schell, Michael J\|Teer, Jamie K\|Greenawalt, Danielle M\|Yang, Mingli\|Yeatman, Timothy J
PMID:	25974029

448.
Journal:	Clin Nucl Med. 2015 Aug;40(8):621-6.
Title:	Genetic Alterations in Colorectal Cancer Have Different Patterns on 18F-FDG PET/CT.
Author:	Chen, Shang-Wen\|Lin, Chien-Yu\|Ho, Cheng-Man\|Chang, Ya-Sian\|Yang, Shu-Fen\|Kao, Chia-Hung\|Chang, Jan-Gowth
PMID:	26018692

449.
Journal:	JAMA Oncol. 2015 May;1(2):214-21.
Title:	Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry.
Author:	Yurgelun, Matthew B\|Masciari, Serena\|Joshi, Victoria A\|Mercado, Rowena C\|Lindor, Noralane M\|Gallinger, Steven\|Hopper, John L\|Jenkins, Mark A\|Buchanan, Daniel D\|Newcomb, Polly A\|Potter, John D\|Haile, Robert W\|Kucherlapati, Raju\|Syngal, Sapna
PMID:	26086041

450.
Journal:	PLoS One. 2015 Jul 17;10(7):e0132435.
Title:	Chlorinated Water Modulates the Development of Colorectal Tumors with Chromosomal Instability and Gut Microbiota in Apc-Deficient Mice.
Author:	Sasada, Tatsunari\|Hinoi, Takao\|Saito, Yasufumi\|Adachi, Tomohiro\|Takakura, Yuji\|Kawaguchi, Yasuo\|Sotomaru, Yusuke\|Sentani, Kazuhiro\|Oue, Naohide\|Yasui, Wataru\|Ohdan, Hideki
PMID:	26186212

451.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2175-86.
Title:	Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.
Author:	Raja, Meera\|Zverev, Matt\|Seipel, Katja\|Williams, Geraint T\|Clarke, Alan R\|Shaw, Paul H S
PMID:	26206338

452.
Journal:	J Pathol. 2015 Dec;237(4):508-19.
Title:	Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis.
Author:	McCleland, Mark L\|Soukup, Tim M\|Liu, Scot D\|Esensten, Jonathan H\|de Sousa e Melo, Felipe\|Yaylaoglu, Murat\|Warming, Soren\|Roose-Girma, Merone\|Firestein, Ron
PMID:	26235356

453.
Journal:	J Clin Biochem Nutr. 2015 Jul;57(1):39-43.
Title:	Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin.
Author:	Shimizu, Satomi\|Miyamoto, Shingo\|Fujii, Gen\|Nakanishi, Ruri\|Onuma, Wakana\|Ozaki, Yoshihiko\|Fujimoto, Kyoko\|Yano, Tomohiro\|Mutoh, Michihiro
PMID:	26236099

454.
Journal:	Carcinogenesis. 2015 Oct;36(10):1245-53.
Title:	Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles.
Author:	Pan, Pan\|Skaer, Chad W\|Wang, Hsin-Tzu\|Stirdivant, Steven M\|Young, Matthew R\|Oshima, Kiyoko\|Stoner, Gary D\|Lechner, John F\|Huang, Yi-Wen\|Wang, Li-Shu
PMID:	26246425

455.
Journal:	Int J Mol Med. 2015 Oct;36(4):1049-56.
Title:	Identification of a novel mutation associated with familial adenomatous polyposis and colorectal cancer.
Author:	Li, Fei-Feng\|Liu, Zheng\|Yan, Peng\|Shao, Xin\|Deng, Xia\|Sam, Christine\|Chen, Ying-Gang\|Xu, Yong-Peng\|Wang, Xi-Shan\|Wang, Gui-Yu\|Liu, Shu-Lin
PMID:	26252958

456.
Journal:	Oncotarget. 2015 Sep 29;6(29):27267-74.
Title:	A novel pathogenic germline mutation in the adenomatous polyposis coli gene in a Chinese family with familial adenomatous coli.
Author:	Jiang, Shan-Shan\|Li, Jian-Jun\|Li, Yin\|He, Long-Jun\|Wang, Qi-Jing\|Weng, D Sheng\|Pan, Ke\|Liu, Qing\|Zhao, Jing-Jing\|Pan, Qiu-Zhong\|Zhang, Xiao-Fei\|Tang, Yan\|Chen, Chang-Long\|Zhang, Hong-Xia\|Xu, Guo-Liang\|Zeng, Yi-Xin\|Xia, Jian-Chuan
PMID:	26311738

457.
Journal:	J Surg Case Rep. 2015 Sep 28;2015(9). pii: rjv118.
Title:	Two different nucleotide substitutions of APC gene in a family with familial adenomatous polyposis.
Author:	Eser, Betul\|Yildar, Murat
PMID:	26416840

458.
Journal:	Colloids Surf B Biointerfaces. 2015 Dec 1;136:694-703.
Title:	Multistage vector delivery of sulindac and silymarin for prevention of colon cancer.
Author:	Scavo, Maria Principia\|Gentile, Emanuela\|Wolfram, Joy\|Gu, Jianhua\|Barone, Michele\|Evangelopoulos, Michael\|Martinez, Jonathan O\|Liu, Xuewu\|Celia, Christian\|Tasciotti, Ennio\|Vilar, Eduardo\|Shen, Haifa
PMID:	26513752

459.
Journal:	PLoS Genet. 2015 Nov 3;11(11):e1005638.
Title:	Tissue-Specific Effects of Reduced beta-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium.
Author:	Feng, Ying\|Sakamoto, Naoya\|Wu, Rong\|Liu, Jie-Yu\|Wiese, Alexandra\|Green, Maranne E\|Green, Megan\|Akyol, Aytekin\|Roy, Badal C\|Zhai, Yali\|Cho, Kathleen R\|Fearon, Eric R
PMID:	26528816

460.
Journal:	Tumori. 2016 Jan-Feb;102(1):40-4.
Title:	Wireless capsule endoscopy in adolescents with familial adenomatous polyposis.
Author:	Cavallo, Debora\|Ballardini, Giovanni\|Ferrari, Andrea\|Delconte, Gabriele\|Signoroni, Stefano\|Sala, Paola\|Chiaravalli, Stefano\|Massimino, Maura\|Bertario, Lucio\|Vitellaro, Marco
PMID:	26219574

461.
Journal:	Mol Biol Cell. 2016 Feb 1;27(3):466-82.
Title:	APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane.
Author:	Mills, Kate M\|Brocardo, Mariana G\|Henderson, Beric R
PMID:	26658612

462.
Journal:	Mol Cancer Res. 2016 Apr;14(4):385-96.
Title:	KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Author:	Ghaleb, Amr M\|Elkarim, Enas A\|Bialkowska, Agnieszka B\|Yang, Vincent W
PMID:	26839262

463.
Journal:	PLoS One. 2016 Feb 10;11(2):e0147217.
Title:	Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy.
Author:	Feldman, Michal\|Hershkovitz, Israel\|Sklan, Ella H\|Kahila Bar-Gal, Gila\|Pap, Ildiko\|Szikossy, Ildiko\|Rosin-Arbesfeld, Rina
PMID:	26863316

464.
Journal:	Cancer Metastasis Rev. 2016 Mar;35(1):63-74.
Title:	Molecular evolution of colorectal cancer: from multistep carcinogenesis to the big bang.
Author:	Amaro, Adriana\|Chiara, Silvana\|Pfeffer, Ulrich
PMID:	26947218

465.
Journal:	Oncotarget. 2016 May 17;7(20):28947-60.
Title:	Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer.
Author:	Harris, Kelly L\|Pulliam, Stephanie R\|Okoro, Emmanuel\|Guo, Zhongmao\|Washington, Mary K\|Adunyah, Samuel E\|Amos-Landgraf, James M\|Ramesh, Aramandla
PMID:	26959117

466.
Journal:	Proteomics. 2016 May;16(10):1557-69.
Title:	Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author:	Tai, William Chi-Shing\|Wong, Wing-Yan\|Lee, Magnolia Muk-Lan\|Chan, Brandon Dow\|Lu, Cheng\|Hsiao, Wen-Luan Wendy
PMID:	26970558

467.
Journal:	BMC Cancer. 2016 Mar 12;16:213.
Title:	Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	26970738

468.
Journal:	Cell Rep. 2016 Mar 22;14(11):2562-75.
Title:	The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Author:	Koblansky, A Alicia\|Truax, Agnieszka D\|Liu, Rongrong\|Montgomery, Stephanie A\|Ding, Shengli\|Wilson, Justin E\|Brickey, W June\|Muhlbauer, Marcus\|McFadden, Rita-Marie T\|Hu, Peizhen\|Li, Zengshan\|Jobin, Christian\|Lund, Pauline Kay\|Ting, Jenny P-Y
PMID:	26971998

469.
Journal:	Carcinogenesis. 2016 May;37(5):491-9.
Title:	Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model.
Author:	Savari, Sayeh\|Chandrashekar, Naveen Kumar\|Osman, Janina\|Douglas, Desiree\|Bellamkonda, Kishan\|Jonsson, Gunilla\|Juhas, Maria\|Greicius, Gedas\|Pettersson, Sven\|Sjolander, Anita
PMID:	26979937

470.
Journal:	World J Gastrointest Endosc. 2016 Mar 10;8(5):252-8.
Title:	New era of colorectal cancer screening.
Author:	El Zoghbi, Maysaa\|Cummings, Linda C
PMID:	26981176

471.
Journal:	Genom Data. 2016 Feb 3;7:293-6.
Title:	Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells.
Author:	King, Lauren E\|Love, Christopher G\|Sieber, Oliver M\|Faux, Maree C\|Burgess, Antony W
PMID:	26981430

472.
Journal:	Carcinogenesis. 2016 Jun;37(6):635-645.
Title:	Red meat and colorectal cancer: Nrf2-dependent antioxidant response contributes to the resistance of preneoplastic colon cells to fecal water of hemoglobin- and beef-fed rats.
Author:	Surya, Reggie\|Helies-Toussaint, Cecile\|Martin, Oceane C\|Gauthier, Thierry\|Gueraud, Francoise\|Tache, Sylviane\|Naud, Nathalie\|Jouanin, Isabelle\|Chantelauze, Celine\|Durand, Denys\|Joly, Charlotte\|Pujos-Guillot, Estelle\|Pierre, Fabrice H\|Huc, Laurence
PMID:	26992899

473.
Journal:	Genes Chromosomes Cancer. 2016 Jul;55(7):577-90.
Title:	Lentivirus-mediated somatic recombination and development of a novel mouse model for sporadic colorectal cancer.
Author:	Vaish, Vivek\|Kim, Joohwee\|Shim, Minsub
PMID:	27037682

474.
Journal:	Oncogene. 2016 Nov 10;35(45):5839-5849.
Title:	Intestinal knockout of Nedd4 enhances growth of Apc(min) tumors.
Author:	Lu, C\|Thoeni, C\|Connor, A\|Kawabe, H\|Gallinger, S\|Rotin, D
PMID:	27086928

475.
Journal:	Cancer Biol Ther. 2016 Jun 2;17(6):657-63.
Title:	Fibersol-2 induces apoptosis of Apc-deficient colorectal Cancer (SW480) cells and decreases polyp formation in Apc MIN mice.
Author:	Sancho, Sara Cuesta\|Olson, Susan Losee\|Young So, Eui\|Shimomura, Kazuhiro\|Ouchi, Toru\|Preuss, Fabian
PMID:	27143108

476.
Journal:	Sci Rep. 2016 May 4;6:25311.
Title:	Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.
Author:	Saito, Yoshimasa\|Nakaoka, Toshiaki\|Sakai, Kasumi\|Muramatsu, Toshihide\|Toshimitsu, Kohta\|Kimura, Masaki\|Kanai, Takanori\|Sato, Toshiro\|Saito, Hidetsugu
PMID:	27143627

477.
Journal:	Oncotarget. 2016 May 24;7(21):31111-21.
Title:	EphB6 overexpression and Apc mutation together promote colorectal cancer.
Author:	Xu, Dan\|Yuan, Liang\|Liu, Xin\|Li, Mingqi\|Zhang, Fubin\|Gu, Xin Yue\|Zhang, Dongwei\|Yang, Youlin\|Cui, Binbin\|Tong, Jinxue\|Zhou, Jin\|Yu, Zhiwei
PMID:	27145271

478.
Journal:	World J Gastroenterol. 2016 May 7;22(17):4380-8.
Title:	Clinicopathological features of familial adenomatous polyposis in Korean patients.
Author:	Jung, Sung Min\|Yoon, Yong Sik\|Lim, Seok-Byeong\|Yu, Chang Sik\|Kim, Jin Cheon
PMID:	27158207

479.
Journal:	Methods Mol Biol. 2016;1422:309-27.
Title:	Characterization of Colorectal Cancer Development in Apc (min/+) Mice.
Author:	Nalbantoglu, ILKe\|Blanc, Valerie\|Davidson, Nicholas O
PMID:	27246043

480.
Journal:	Oncotarget. 2016 Aug 9;7(32):51665-51673.
Title:	Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype.
Author:	Reed, Karen R\|Song, Fei\|Young, Maddy A\|Hassan, Nurudeen\|Antoine, Daniel J\|Gemici, Nesibe-Princess B\|Clarke, Alan R\|Jenkins, John R
PMID:	27323825

481.
Journal:	Gastroenterology. 2016 Nov;151(5):945-960.e6.
Title:	SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.
Author:	Wong, Chi Chun\|Qian, Yun\|Li, Xiaona\|Xu, Jiaying\|Kang, Wei\|Tong, Joanna H\|To, Ka-Fai\|Jin, Ye\|Li, Weilin\|Chen, Huarong\|Go, Minnie Y Y\|Wu, Jian-Lin\|Cheng, Ka Wing\|Ng, Simon S M\|Sung, Joseph J Y\|Cai, Zongwei\|Yu, Jun
PMID:	27451147

482.
Journal:	Cancer Med. 2016 Sep;5(9):2469-76.
Title:	Ultrasound imaging of splenomegaly as a proxy to monitor colon tumor development in Apc(min716/+) mice.
Author:	Hodgson, Andrea\|Wier, Eric M\|Fu, Kai\|Sun, Xin\|Wan, Fengyi
PMID:	27485505

483.
Journal:	Cancer Prev Res (Phila). 2016 Oct;9(10):812-820.
Title:	Dietary Methyl Donor Depletion Suppresses Intestinal Adenoma Development.
Author:	Hanley, Matthew P\|Kadaveru, Krishna\|Perret, Christine\|Giardina, Charles\|Rosenberg, Daniel W
PMID:	27530130

484.
Journal:	Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11859-11864.
Title:	Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.
Author:	Tetteh, Paul W\|Kretzschmar, Kai\|Begthel, Harry\|van den Born, Maaike\|Korving, Jeroen\|Morsink, Folkert\|Farin, Henner\|van Es, Johan H\|Offerhaus, G Johan A\|Clevers, Hans
PMID:	27708166

485.
Journal:	Cancer Res. 2016 Dec 1;76(23):6877-6887.
Title:	Transcription Factor ZBP-89 Drives a Feedforward Loop of beta-Catenin Expression in Colorectal Cancer.
Author:	Essien, Bryan E\|Sundaresan, Sinju\|Ocadiz-Ruiz, Ramon\|Chavis, Aaron\|Tsao, Amy C\|Tessier, Arthur J\|Hayes, Michael M\|Photenhauer, Amanda\|Saqui-Salces, Milena\|Kang, Anthony J\|Shah, Yatrik M\|Gyorffy, Balazs\|Merchant, Juanita L
PMID:	27758879

486.
Journal:	J Histochem Cytochem. 2016 Dec;64(12):753-767.
Title:	Altered T-Cell Balance in Lymphoid Organs of a Mouse Model of Colorectal Cancer.
Author:	Tanner, Scott M\|Daft, Joseph G\|Hill, Stephanie A\|Martin, Colin A\|Lorenz, Robin G
PMID:	27798287

487.
Journal:	BMC Cancer. 2016 Nov 8;16(1):862.
Title:	A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation?
Author:	Rigter, Lisanne Sara\|Kallenberg, Frank G J\|Bastiaansen, Barbara\|van Os, Theo A M\|van Leeuwen, Floor E\|van Leerdam, Monique Esther\|Dekker, Evelien
PMID:	27821077

488.
Journal:	BMC Cancer. 2016 Dec 23;16(1):952.
Title:	The effect of a germline mutation in the APC gene on beta-catenin in human embryonic stem cells.
Author:	Yedid, Nofar\|Kalma, Yael\|Malcov, Mira\|Amit, Ami\|Kariv, Revital\|Caspi, Michal\|Rosin-Arbesfeld, Rina\|Ben-Yosef, Dalit
PMID:	28010732

489.
Journal:	J Gastrointest Oncol. 2016 Dec;7(6):882-902.
Title:	Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Author:	Al-Shamsi, Humaid O\|Jones, Jeremy\|Fahmawi, Yazan\|Dahbour, Ibrahim\|Tabash, Aziz\|Abdel-Wahab, Reham\|Abousamra, Ahmed O S\|Shaw, Kenna R\|Xiao, Lianchun\|Hassan, Manal M\|Kipp, Benjamin R\|Kopetz, Scott\|Soliman, Amr S\|McWilliams, Robert R\|Wolff, Robert A
PMID:	28078112

490.
Journal:	Oncogene. 2017 Jun 15;36(24):3397-3405.
Title:	Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells.
Author:	van Lidth de Jeude, J F\|Meijer, B J\|Wielenga, M C B\|Spaan, C N\|Baan, B\|Rosekrans, S L\|Meisner, S\|Shen, Y H\|Lee, A S\|Paton, J C\|Paton, A W\|Muncan, V\|van den Brink, G R\|Heijmans, J
PMID:	27819675

491.
Journal:	J Nutr Biochem. 2017 Jan;39:126-133.
Title:	Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity.
Author:	Niku, Mikael\|Pajari, Anne-Maria\|Sarantaus, Laura\|Paivarinta, Essi\|Storvik, Markus\|Heiman-Lindh, Anu\|Suokas, Santeri\|Nystrom, Minna\|Mutanen, Marja
PMID:	27833053

492.
Journal:	Nat Commun. 2017 Jan 25;8:14093.
Title:	DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Author:	Mamlouk, Soulafa\|Childs, Liam Harold\|Aust, Daniela\|Heim, Daniel\|Melching, Friederike\|Oliveira, Cristiano\|Wolf, Thomas\|Durek, Pawel\|Schumacher, Dirk\|Blaker, Hendrik\|von Winterfeld, Moritz\|Gastl, Bastian\|Mohr, Kerstin\|Menne, Andrea\|Zeugner, Silke\|Redmer, To
PMID:	28120820

493.
Journal:	Mol Cancer Res. 2017 Feb 9;15(3):317-327.
Title:	Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.
Author:	Foley, Tyler M\|Payne, Susan N\|Pasch, Cheri A\|Yueh, Alex E\|Van De Hey, Dana R\|Korkos, Demetra P\|Clipson, Linda\|Maher, Molly E\|Matkowskyj, Kristina A\|Newton, Michael A\|Deming, Dustin A
PMID:	28184015

494.
Journal:	Genes Dev. 2017 Feb 15;31(4):370-382.
Title:	Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Author:	Boutin, Adam T\|Liao, Wen-Ting\|Wang, Melody\|Hwang, Soyoon Sarah\|Karpinets, Tatiana V\|Cheung, Hannah\|Chu, Gerald C\|Jiang, Shan\|Hu, Jian\|Chang, Kyle\|Vilar, Eduardo\|Song, Xingzhi\|Zhang, Jianhua\|Kopetz, Scott\|Futreal, Andrew\|Wang, Y Alan\|Kwong, Lawrence N\|DePi
PMID:	28289141

495.
Journal:	Endocr Relat Cancer. 2017 Jun;24(6):253-265.
Title:	Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Author:	Tabrizian, Tahmineh\|Wang, Donghai\|Guan, Fangxia\|Hu, Zunju\|Beck, Amanda P\|Delahaye, Fabien\|Huffman, Derek M
PMID:	28351943

496.
Journal:	Oncogene. 2017 Aug 17;36(33):4810-4816.
Title:	Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
Author:	Sumner, E T\|Chawla, A T\|Cororaton, A D\|Koblinski, J E\|Kovi, R C\|Love, I M\|Szomju, B B\|Korwar, S\|Ellis, K C\|Grossman, S R
PMID:	28414304

497.
Journal:	Nat Biotechnol. 2017 Jun;35(6):569-576.
Title:	In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Author:	Roper, Jatin\|Tammela, Tuomas\|Cetinbas, Naniye Malli\|Akkad, Adam\|Roghanian, Ali\|Rickelt, Steffen\|Almeqdadi, Mohammad\|Wu, Katherine\|Oberli, Matthias A\|Sanchez-Rivera, Francisco J\|Park, Yoona K\|Liang, Xu\|Eng, George\|Taylor, Martin S\|Azimi, Roxana\|Kedrin, Dmi
PMID:	28459449

498.
Journal:	In Vivo. 2017 Jul-Aug;31(4):527-542.
Title:	K-ras Mutations as the Earliest Driving Force in a Subset of Colorectal Carcinomas.
Author:	Margetis, Nikolaos\|Kouloukoussa, Myrsini\|Pavlou, Kyriaki\|Vrakas, Spyridon\|Mariolis-Sapsakos, Theodoros
PMID:	28652417

499.
Journal:	PLoS Genet. 2017 Jul 14;13(7):e1006870.
Title:	Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.
Author:	Tian, Ai\|Benchabane, Hassina\|Wang, Zhenghan\|Zimmerman, Chloe\|Xin, Nan\|Perochon, Jessica\|Kalna, Gabriela\|Sansom, Owen J\|Cheng, Chao\|Cordero, Julia B\|Ahmed, Yashi
PMID:	28708826

500.
Journal:	Curr Cancer Drug Targets. 2017 Aug 8. pii: CCDT-EPUB-85166.
Title:	Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.
Author:	Saxena, Ashish\|Tammali, Ravinder\|Ramana, Kota V\|Srivastava, Satish K
PMID:	28786349

501.
Journal:	J Pathol. 2017 Nov;243(3):366-375.
Title:	Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study.
Author:	Barrow, Timothy M\|Klett, Hagen\|Toth, Reka\|Bohm, Jurgen\|Gigic, Biljana\|Habermann, Nina\|Scherer, Dominique\|Schrotz-King, Petra\|Skender, Stephanie\|Abbenhardt-Martin, Clare\|Zielske, Lin\|Schneider, Martin\|Ulrich, Alexis\|Schirmacher, Peter\|Herpel, Esther\|Brenne
PMID:	28791728

502.
Journal:	Curr Biol. 2017 Aug 21;27(16):R805-R807.
Title:	Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions.
Author:	Nathke, Inke
PMID:	28829967

503.
Journal:	Oncotarget. 2017 Jun 7;8(32):53262-53275.
Title:	Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells.
Author:	Vaish, Vivek\|Kim, Joohwee\|Shim, Minsub
PMID:	28881809

504.
Journal:	Curr Probl Cancer. 2017 Nov - Dec;41(6):388-397.
Title:	Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.
Author:	Nejadtaghi, Mahdieh\|Jafari, Hamideh\|Farrokhi, Effat\|Samani, Keihan Ghatreh
PMID:	29096939

505.
Journal:	Cancer Metab. 2017 Nov 30;5:10.
Title:	PKM2 is not required for colon cancer initiated by APC loss.
Author:	Lau, Allison N\|Israelsen, William J\|Roper, Jatin\|Sinnamon, Mark J\|Georgeon, Larissa\|Dayton, Talya L\|Hillis, Alissandra L\|Yilmaz, Omer H\|Di Vizio, Dolores\|Hung, Kenneth E\|Vander Heiden, Matthew G
PMID:	29214019

506.
Journal:	Saudi J Biol Sci. 2017 Dec;24(8):1781-1786.
Title:	Establishment of optimal regulatory network of colorectal cancer based on p42.3 protein.
Author:	Hao, Yibin\|Zhang, Jianhua\|Shan, Guoyong\|Zhang, Ning\|Jin, Wenwen\|Nan, Kejun
PMID:	29551923

507.
Journal:	J Cell Biochem. 2018 Jul;119(7):5104-5117.
Title:	Introduction of hsa-miR-103a and hsa-miR-1827 and hsa-miR-137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma.
Author:	Fasihi, Ali\|M Soltani, Bahram\|Atashi, Amir\|Nasiri, Shirzad
PMID:	28817181

508.
Journal:	Mol Nutr Food Res. 2018 Jan;62(2).
Title:	Pomegranate By-Products in Colorectal Cancer Chemoprevention: Effects in Apc-Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo.
Author:	Tortora, Katia\|Femia, Angelo Pietro\|Romagnoli, Andrea\|Sineo, Irene\|Khatib, Mohamad\|Mulinacci, Nadia\|Giovannelli, Lisa\|Caderni, Giovanna
PMID:	28948694

509.
Journal:	Gut. 2018 Jul;67(7):1290-1298.
Title:	Differential preventive activity of sulindac and atorvastatin in Apc(+/Min-FCCC)mice with or without colorectal adenomas.
Author:	Chang, Wen-Chi L\|Jackson, Christina\|Riel, Stacy\|Cooper, Harry S\|Devarajan, Karthik\|Hensley, Harvey H\|Zhou, Yan\|Vanderveer, Lisa A\|Nguyen, Minhhuyen T\|Clapper, Margie L
PMID:	29122850

510.
Journal:	Cancer Res. 2018 Feb 1;78(3):617-630.
Title:	Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients.
Author:	Hankey, William\|McIlhatton, Michael A\|Ebede, Kenechi\|Kennedy, Brian\|Hancioglu, Baris\|Zhang, Jie\|Brock, Guy N\|Huang, Kun\|Groden, Joanna
PMID:	29212857

511.
Journal:	Mol Cancer Res. 2018 Mar;16(3):486-495.
Title:	Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.
Author:	Drew, David A\|Mo, Allen\|Grady, James J\|Stevens, Richard G\|Levine, Joel B\|Brenner, Bruce M\|Anderson, Joseph C\|Forouhar, Faripour\|O'Brien, Michael J\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	29222172

512.
Journal:	Pathol Res Pract. 2018 Jan;214(1):64-71.
Title:	Prognostic impact of changes in base excision repair machinery in sporadic colorectal cancer.
Author:	Azambuja, Daniel B\|Leguisamo, Natalia M\|Gloria, Helena C\|Kalil, Antonio Nocchi\|Rhoden, Ernani\|Saffi, Jenifer
PMID:	29254784

513.
Journal:	Cancer Res. 2018 Mar 1;78(5):1334-1346.
Title:	Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Author:	Sakai, Eri\|Nakayama, Mizuho\|Oshima, Hiroko\|Kouyama, Yuta\|Niida, Atsushi\|Fujii, Satoshi\|Ochiai, Atsushi\|Nakayama, Keiichi I\|Mimori, Koshi\|Suzuki, Yutaka\|Hong, Chang Pyo\|Ock, Chan-Young\|Kim, Seong-Jin\|Oshima, Masanobu
PMID:	29282223

514.
Journal:	Cancer Prev Res (Phila). 2018 Feb;11(2):81-92.
Title:	Cyclic-GMP-Elevating Agents Suppress Polyposis in Apc(Min) mice by Targeting the Preneoplastic Epithelium.
Author:	Sharman, Sarah K\|Islam, Bianca N\|Hou, Yali\|Singh, Nagendra\|Berger, Franklin G\|Sridhar, Subbaramiah\|Yoo, Wonsuk\|Browning, Darren D
PMID:	29301746

515.
Journal:	Med Hypotheses. 2018 Jan;110:110-113.
Title:	Iron therapy as treatment of anemia: A potentially detrimental and hazardous strategy in colorectal cancer patients.
Author:	Wilson, M J\|Harlaar, J J\|Jeekel, J\|Schipperus, M\|Zwaginga, J J
PMID:	29317052

516.
Journal:	Oncol Rep. 2018 Mar;39(3):1269-1275.
Title:	Knockdown of immature colon carcinoma transcript 1 induces suppression of proliferation, S-phase arrest and apoptosis in leukemia cells.
Author:	Li, Guang-Yao\|Liu, Ji-Zhu\|Zhang, Li\|Liu, Guo-Zhen\|Li, Shuang-Jing\|Xiao, Tai-Wu\|Wang, Jing-Xia\|Wang, Le-Xin\|Hou, Ming
PMID:	29328466

517.
Journal:	Clin Colorectal Cancer. 2018 Jun;17(2):e293-e305.
Title:	Update on Hereditary Colorectal Cancer: Improving the Clinical Utility of Multigene Panel Testing.
Author:	Lorans, Marie\|Dow, Eryn\|Macrae, Finlay A\|Winship, Ingrid M\|Buchanan, Daniel D
PMID:	29454559

518.
Journal:	J Transl Med. 2018 Feb 27;16(1):45.
Title:	A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.
Author:	Freitas, Micaela\|Ferreira, Fabio\|Carvalho, Sonia\|Silva, Fernanda\|Lopes, Paula\|Antunes, Luis\|Salta, Sofia\|Diniz, Francisca\|Santos, Lucio Lara\|Videira, Jose Flavio\|Henrique, Rui\|Jeronimo, Carmen
PMID:	29486770

519.
Journal:	Cancer Biol Med. 2018 Feb;15(1):61-69.
Title:	Parkin protein expression and its impact on survival of patients with advanced colorectal cancer.
Author:	da Silva-Camargo, Claudia Caroline Veloso\|Svoboda Baldin, Rosimeri Kuhl\|Costacurta Polli, Nayanne Louise\|Agostinho, Amanda Pereira\|Olandosk, Marcia\|de Noronha, Lucia\|Sotomaior, Vanessa Santos
PMID:	29545969

520.
Journal:	Dis Model Mech. 2018 Mar 7;11(3). pii: 11/3/dmm032300.
Title:	Vitamin D deficiency in the Apc(Pirc/+) rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective.
Author:	Irving, Amy A\|Duchow, Elizabeth G\|Plum, Lori A\|DeLuca, Hector F
PMID:	29590632

521.
Journal:	Evid Based Complement Alternat Med. 2018 Feb 12;2018:6517034.
Title:	A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.
Author:	Liu, Xinkui\|Wu, Jiarui\|Zhang, Dan\|Wang, Kaihuan\|Duan, Xiaojiao\|Zhang, Xiaomeng
PMID:	29619072

522.
Journal:	J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title:	Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Author:	Loree, Jonathan M\|Bailey, Ann M\|Johnson, Amber M\|Yu, Yao\|Wu, Wenhui\|Bristow, Christopher A\|Davis, Jennifer S\|Shaw, Kenna R\|Broaddus, Russell\|Banks, Kimberly C\|Lanman, Richard B\|Meric-Bernstam, Funda\|Overman, Michael J\|Kopetz, Scott\|Raghav, Kanwal
PMID:	29718453

523.
Journal:	Oncol Lett. 2018 May;15(5):8107-8117.
Title:	miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation.
Author:	Chang, Chiu-Chun\|Lin, Chun-Che\|Wang, Chia-Hung\|Huang, Chi-Chou\|Ke, Tao-Wei\|Wei, Po-Li\|Yeh, Ken-Tu\|Hsu, Kai-Cheng\|Hsu, Nan-Yung\|Cheng, Ya-Wen
PMID:	29731918

524.
Journal:	Gastroenterology. 2018 Sep;155(3):844-851.
Title:	Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.
Author:	Ten Broeke, Sanne W\|van Bavel, Tom C\|Jansen, Anne M L\|Gomez-Garcia, Encarnca\|Hes, Frederik J\|van Hest, Liselot P\|Letteboer, Tom G W\|Olderode-Berends, Maran J W\|Ruano, Dina\|Spruijt, Liesbeth\|Suerink, Manon\|Tops, Carli M\|van Eijk, Ronald\|Morreau, Hans\|van W
PMID:	29758216

525.
Journal:	Oncotarget. 2018 May 8;9(35):23960-23974.
Title:	Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Author:	Oliveira, Duarte Mendes\|Laudanna, Carmelo\|Migliozzi, Simona\|Zoppoli, Pietro\|Santamaria, Gianluca\|Grillone, Katia\|Elia, Laura\|Mignogna, Chiara\|Biamonte, Flavia\|Sacco, Rosario\|Corcione, Francesco\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29844865

526.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20;38(5):511-519.
Title:	[Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Author:	Ai, Xiao-Lan\|Yao, Fang\|Wang, Xiao-Jing\|Duan, Dong-Bei\|Li, Ke\|Hu, Zi-You\|Yin, Guo\|Wang, Mei\|Wu, Bing-Yi
PMID:	29891445

527.
Journal:	Clin Cancer Res. 2018 Oct 1;24(19):4715-4725.
Title:	Clonal Structures of Regionally Synchronous Gastric Adenomas and Carcinomas.
Author:	Jung, Seung-Hyun\|Kim, Shin Young\|An, Chang Hyeok\|Lee, Sung Hak\|Jung, Eun Sun\|Park, Hyeon-Chun\|Kim, Min Sung\|Chung, Yeun-Jun\|Lee, Sug Hyung
PMID:	29945994

528.
Journal:	Cancer Res. 2018 Sep 1;78(17):4839-4852.
Title:	Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.
Author:	Stevens, Payton D\|Wen, Yang-An\|Xiong, Xiaopeng\|Zaytseva, Yekaterina Y\|Li, Austin T\|Wang, Chi\|Stevens, Ashley T\|Farmer, Trevor N\|Gan, Tong\|Weiss, Heidi L\|Inagaki, Masaki\|Marchetto, Sylvie\|Borg, Jean-Paul\|Gao, Tianyan
PMID:	29980571

529.
Journal:	Oncol Lett. 2018 Aug;16(2):1863-1868.
Title:	Aneuploidy of chromosome 8 and mutation of circulating tumor cells predict pathologic complete response in the treatment of locally advanced rectal cancer.
Author:	Wan, Jue-Feng\|Li, Xue-Qin\|Zhang, Jing\|Yang, Li-Feng\|Zhu, Ji\|Li, Gui-Chao\|Liang, Li-Ping\|Shen, Li-Jun\|Zhang, Hui\|Li, Jing\|Zhang, Yi-Tong\|Chen, Chang-Yue\|Zhang, Zhen
PMID:	30008877

530.
Journal:	J Clin Pathol. 2018 Oct 12. pii: jclinpath-2018-205412.
Title:	Evaluation of a novel liquid biopsy-based ColoScape assay for mutational analysis of colorectal neoplasia and triage of FIT+ patients: a pilot study.
Author:	Scimia, Mauro\|Du, Jinwei\|Pepe, Francesco\|Bianco, Maria Antonia\|Russo Spena, Silvana\|Patell-Socha, Farah\|Sun, Qing\|Powell, Michael J\|Malapelle, Umberto\|Troncone, Giancarlo
PMID:	30315134