Primary Site >> Pancreatic Cancer
Gene >> ALOX5
| 1. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1999 Dec 20;266(2):392-9. | ||||||||||
| Title: | Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells. | ||||||||||
| Author: | Ding, X Z|Kuszynski, C A|El-Metwally, T H|Adrian, T E | ||||||||||
| PMID: | 10600514 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1999 Jul 22;261(1):218-23. | ||||||||||
| Title: | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. | ||||||||||
| Author: | Ding, X Z|Iversen, P|Cluck, M W|Knezetic, J A|Adrian, T E | ||||||||||
| PMID: | 10405349 | ||||||||||
| 3. | |||||||||||
| Journal: | Carcinogenesis. 2001 Mar;22(3):473-9. | ||||||||||
| Title: | Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas. | ||||||||||
| Author: | Weddle, D L|Tithoff, P|Williams, M|Schuller, H M | ||||||||||
| PMID: | 11238189 | ||||||||||
| 4. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2001 Jun;939:45-51. | ||||||||||
| Title: | Neurogenesis and neuroprotection in the adult brain. A putative role for 5-lipoxygenase? | ||||||||||
| Author: | Manev, H|Uz, T|Manev, R|Zhang, Z | ||||||||||
| PMID: | 11462800 | ||||||||||
| 5. | |||||||||||
| Journal: | Am J Pathol. 2002 Aug;161(2):421-8. | ||||||||||
| Title: | 5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue. | ||||||||||
| Author: | Hennig, Rene|Ding, Xian-Zhong|Tong, Wei-Gang|Schneider, Matthias B|Standop, Jens|Friess, Helmut|Buchler, Markus W|Pour, Parviz M|Adrian, Thomas E | ||||||||||
| PMID: | 12163367 | ||||||||||
| 6. | |||||||||||
| Journal: | Mol Cancer Ther. 2002 Sep;1(11):929-35. | ||||||||||
| Title: | Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway. | ||||||||||
| Author: | Tong, Wei-Gang|Ding, Xian-Zhong|Witt, Richard C|Adrian, Thomas E | ||||||||||
| PMID: | 12481414 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncology. 2003;65(4):285-94. | ||||||||||
| Title: | Multiple signal pathways are involved in the mitogenic effect of 5(S)-HETE in human pancreatic cancer. | ||||||||||
| Author: | Ding, Xian-Zhong|Tong, Wei-Gang|Adrian, Thomas E | ||||||||||
| PMID: | 14707447 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Cancer. 2004 Sep 10;111(4):611-6. | ||||||||||
| Title: | Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients. | ||||||||||
| Author: | Heller, Axel R|Rossel, Thomas|Gottschlich, Birgit|Tiebel, Oliver|Menschikowski, Mario|Litz, Rainer J|Zimmermann, Thomas|Koch, Thea | ||||||||||
| PMID: | 15239141 | ||||||||||
| 9. | |||||||||||
| Journal: | Anticancer Drugs. 2005 Jun;16(5):467-73. | ||||||||||
| Title: | A novel anti-pancreatic cancer agent, LY293111. | ||||||||||
| Author: | Ding, Xian-Zhong|Talamonti, Marks S|Bell, Richard H Jr|Adrian, Thomas E | ||||||||||
| PMID: | 15846111 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2005 Jul 15;65(14):6011-6. | ||||||||||
| Title: | 5-Lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions. | ||||||||||
| Author: | Hennig, Rene|Grippo, Paul|Ding, Xian-Zhong|Rao, Sambasiva M|Buchler, Markus W|Friess, Helmut|Talamonti, Mark S|Bell, Richard H|Adrian, Thomas E | ||||||||||
| PMID: | 16024599 | ||||||||||
| 11. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2005 Dec;289(6):G1137-47. Epub 2005 Jul | ||||||||||
| Title: | Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. | ||||||||||
| Author: | Edderkaoui, Mouad|Hong, Peggy|Vaquero, Eva C|Lee, Jong K|Fischer, Lars|Friess, Helmut|Buchler, Markus W|Lerch, Markus M|Pandol, Stephen J|Gukovskaya, Anna S | ||||||||||
| PMID: | 16037546 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncogene. 2007 Aug 23;26(39):5784-92. Epub 2007 Mar 19. | ||||||||||
| Title: | Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor. | ||||||||||
| Author: | Covey, T M|Edes, K|Fitzpatrick, F A | ||||||||||
| PMID: | 17369849 | ||||||||||
| 13. | |||||||||||
| Journal: | Neoplasia. 2007 Nov;9(11):917-26. | ||||||||||
| Title: | 15-lipoxygenase-1 production is lost in pancreatic cancer and overexpression of the gene inhibits tumor cell growth. | ||||||||||
| Author: | Hennig, Rene|Kehl, Timo|Noor, Seema|Ding, Xian-Zhong|Rao, Sambasiva M|Bergmann, Frank|Furstenberger, Gerhard|Buchler, Markus W|Friess, Helmut|Krieg, Peter|Adrian, Thomas E | ||||||||||
| PMID: | 18030360 | ||||||||||
| 14. | |||||||||||
| Journal: | Biochim Biophys Acta. 2007 Jul;1770(7):1021-7. Epub 2007 Mar 15. | ||||||||||
| Title: | Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines. | ||||||||||
| Author: | Zhou, G X|Ding, X L|Huang, J F|Zhang, H|Wu, S B | ||||||||||
| PMID: | 17434678 | ||||||||||
| 15. | |||||||||||
| Journal: | World J Gastroenterol. 2008 Apr 28;14(16):2494-500. | ||||||||||
| Title: | Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2. | ||||||||||
| Author: | Zhang, Bo|Wang, Chang-Liang|Zhao, Wen-Hua|Lv, Ming|Wang, Chun-Ying|Zhong, Wei-Xia|Zhou, Wu-Yuan|Yu, Wen-Sheng|Zhang, Yan|Li, Sheng | ||||||||||
| PMID: | 18442195 | ||||||||||
| 16. | |||||||||||
| Journal: | PPAR Res. 2008;2008:827096. | ||||||||||
| Title: | The Role of PPARgamma Receptors and Leukotriene B(4) Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer. | ||||||||||
| Author: | Adrian, Thomas E|Hennig, Rene|Friess, Helmut|Ding, Xianzhong | ||||||||||
| PMID: | 19190780 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2012 Jan;69(1):253-61. | ||||||||||
| Title: | Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model. | ||||||||||
| Author: | Ding, Xiaoling|Zhou, Xiaorong|Zhang, Haifeng|Qing, Jingdan|Qiang, Hui|Zhou, Guoxiong | ||||||||||
| PMID: | 21713446 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e43376. | ||||||||||
| Title: | Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. | ||||||||||
| Author: | Al-Wadei, Hussein A N|Al-Wadei, Mohammed H|Ullah, Mohammad F|Schuller, Hildegard M | ||||||||||
| PMID: | 22916251 | ||||||||||
| 19. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Aug 21;20(31):10729-39. | ||||||||||
| Title: | Involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase. | ||||||||||
| Author: | Knab, Lawrence M|Grippo, Paul J|Bentrem, David J | ||||||||||
| PMID: | 25152576 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncol Rep. 2015 Feb;33(2):661-8. | ||||||||||
| Title: | Inhibition of 5-lipoxygenase triggers apoptosis in pancreatic cancer cells. | ||||||||||
| Author: | Zhou, Guo-Xiong|Ding, Xiao-Ling|Wu, Sheng-Bao|Zhang, Hai-Feng|Cao, Wei|Qu, Li-Shuai|Zhang, Hong | ||||||||||
| PMID: | 25483364 | ||||||||||
| 21. | |||||||||||
| Journal: | Anticancer Agents Med Chem. 2015;15(8):1066-77. | ||||||||||
| Title: | 5-Lipoxygenase and cyclooxygenase inhibitory dammarane triterpenoid 1 from Borassus flabellifer seed coat inhibits tumor necrosis factor-alpha secretion in LPSInduced THP-1 human monocytes and induces apoptosis in MIA PaCa-2 pancreatic cancer cells. | ||||||||||
| Author: | Yarla, Nagendra Sastry|Azad, Rajaram|Basha, Mahaboob|Rajack, Abdul|Kaladhar, D S V G K|Allam, Bharat Kumar|Pragada, Rajeswara Rao|Singh, Krishna Nand|K, Sunanda Kumari|Pallu, Reddanna|Parimi, Umadevi|Bishayee, Anupam|Duddukuri, Govinda Rao | ||||||||||
| PMID: | 25642980 | ||||||||||
| 22. | |||||||||||
| Journal: | Immunology. 2017 Sep;152(1):36-51. | ||||||||||
| Title: | Loss of natural killer T cells promotes pancreatic cancer in LSL-Kras(G12D/+) mice. | ||||||||||
| Author: | Janakiram, Naveena B|Mohammed, Altaf|Bryant, Taylor|Ritchie, Rebekah|Stratton, Nicole|Jackson, Lydgia|Lightfoot, Stan|Benbrook, Doris M|Asch, Adam S|Lang, Mark L|Rao, Chinthalapally V | ||||||||||
| PMID: | 28419443 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pharm Pharmacol. 2018 Jul;70(7):952-963. | ||||||||||
| Title: | Evidence for the anti-inflammatory activity of Bupleurum marginatum (Apiaceae) extracts using in vitro and in vivo experiments supported by virtual screening. | ||||||||||
| Author: | Ashour, Mohamed L|Youssef, Fadia S|Gad, Haidy A|El-Readi, Mahmoud Z|Bouzabata, Amel|Abuzeid, Riham M|Sobeh, Mansour|Wink, Michael | ||||||||||
| PMID: | 29611204 | ||||||||||