Primary Site >> Colorectal Cancer
Gene >> ALOX15
| 1. | |||||||||||
| Journal: | Adv Exp Med Biol. 1997;400B:599-604. | ||||||||||
| Title: | Regulation of 15-lipoxygenase expression by cytokines. | ||||||||||
| Author: | Brinckmann, R|Kuhn, H | ||||||||||
| PMID: | 9547609 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Lett. 1997 Jun 24;116(2):213-23. | ||||||||||
| Title: | Production of arachidonic acid metabolites by the colon adenocarcinoma cell line HT29 cl.19A and their effect on chloride secretion. | ||||||||||
| Author: | Battu, S|Clement, G|Heyman, M|Wal, J M|Cook-Moreau, J|Desjeux, J F|Beneytout, J L | ||||||||||
| PMID: | 9215866 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 1998 Aug 21;273(34):21569-77. | ||||||||||
| Title: | Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation. | ||||||||||
| Author: | Kamitani, H|Geller, M|Eling, T | ||||||||||
| PMID: | 9705287 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 1999 Jan 15;59(2):360-6. | ||||||||||
| Title: | Expression of 15-lipoxygenase-1 in human colorectal cancer. | ||||||||||
| Author: | Ikawa, H|Kamitani, H|Calvo, B F|Foley, J F|Eling, T E | ||||||||||
| PMID: | 9927047 | ||||||||||
| 5. | |||||||||||
| Journal: | Carcinogenesis. 1999 Oct;20(10):1985-95. | ||||||||||
| Title: | Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. | ||||||||||
| Author: | Shureiqi, I|Wojno, K J|Poore, J A|Reddy, R G|Moussalli, M J|Spindler, S A|Greenson, J K|Normolle, D|Hasan, A A|Lawrence, T S|Brenner, D E | ||||||||||
| PMID: | 10506115 | ||||||||||
| 6. | |||||||||||
| Journal: | J Natl Cancer Inst. 2000 Jul 19;92(14):1136-42. | ||||||||||
| Title: | 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. | ||||||||||
| Author: | Shureiqi, I|Chen, D|Lee, J J|Yang, P|Newman, R A|Brenner, D E|Lotan, R|Fischer, S M|Lippman, S M | ||||||||||
| PMID: | 10904086 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2000 Dec 15;60(24):6846-50. | ||||||||||
| Title: | 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. | ||||||||||
| Author: | Shureiqi, I|Chen, D|Lotan, R|Yang, P|Newman, R A|Fischer, S M|Lippman, S M | ||||||||||
| PMID: | 11156377 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 2001 Jun 15;61(12):4879-84. | ||||||||||
| Title: | Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. | ||||||||||
| Author: | Shureiqi, I|Xu, X|Chen, D|Lotan, R|Morris, J S|Fischer, S M|Lippman, S M | ||||||||||
| PMID: | 11406566 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2001 Sep 1;61(17):6307-12. | ||||||||||
| Title: | Lipoxygenase modulation to reverse carcinogenesis. | ||||||||||
| Author: | Shureiqi, I|Lippman, S M | ||||||||||
| PMID: | 11522616 | ||||||||||
| 10. | |||||||||||
| Journal: | Biochem Pharmacol. 2001 Nov 1;62(9):1175-83. | ||||||||||
| Title: | Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. | ||||||||||
| Author: | Hong, J|Smith, T J|Ho, C T|August, D A|Yang, C S | ||||||||||
| PMID: | 11705450 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2002 Feb 15;62(4):1178-83. | ||||||||||
| Title: | GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells. | ||||||||||
| Author: | Shureiqi, Imad|Jiang, Wei|Fischer, Susan M|Xu, Xiaochun|Chen, Dongning|Lee, J Jack|Lotan, Reuben|Lippman, Scott M | ||||||||||
| PMID: | 11861401 | ||||||||||
| 12. | |||||||||||
| Journal: | J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19. | ||||||||||
| Title: | Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. | ||||||||||
| Author: | Hsi, Linda C|Wilson, Leigh C|Eling, Thomas E | ||||||||||
| PMID: | 12189136 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Cancer. 2003 Dec 10;107(5):837-43. | ||||||||||
| Title: | 15-hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator-activated receptor gamma-dependent pathway. | ||||||||||
| Author: | Chen, George G|Xu, Hu|Lee, Janet F Y|Subramaniam, Malayannan|Leung, Ka L|Wang, Su H|Chan, Ursula P F|Spelsberg, Thomas C | ||||||||||
| PMID: | 14566836 | ||||||||||
| 14. | |||||||||||
| Journal: | Prostaglandins Leukot Essent Fatty Acids. 2003 May;68(5):323-30. | ||||||||||
| Title: | Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. | ||||||||||
| Author: | Nixon, J B|Kamitani, H|Baek, S J|Eling, T E | ||||||||||
| PMID: | 12711249 | ||||||||||
| 15. | |||||||||||
| Journal: | Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):111-22. | ||||||||||
| Title: | 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. | ||||||||||
| Author: | Yoshinaga, Masahiro|Buchanan, F Gregory|DuBois, Raymond N | ||||||||||
| PMID: | 15165036 | ||||||||||
| 16. | |||||||||||
| Journal: | Ann Surg. 2005 Jun;241(6):941-6; discussion 946-7. | ||||||||||
| Title: | Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. | ||||||||||
| Author: | Heslin, Martin J|Hawkins, Ashley|Boedefeld, William|Arnoletti, J Pablo|Frolov, Andrey|Soong, Richie|Urist, Marshall M|Bland, Kirby I | ||||||||||
| PMID: | 15912043 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2005 Sep 15;65(18):8442-7. | ||||||||||
| Title: | Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells. | ||||||||||
| Author: | Deguchi, Atsuko|Xing, Steven W|Shureiqi, Imad|Yang, Peiying|Newman, Robert A|Lippman, Scott M|Feinmark, Steven J|Oehlen, Bert|Weinstein, I Bernard | ||||||||||
| PMID: | 16166323 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Res. 2005 Sep;3(9):511-7. | ||||||||||
| Title: | Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells. | ||||||||||
| Author: | Kim, Jong-Sik|Baek, Seung Joon|Bottone, Frank G Jr|Sali, Tina|Eling, Thomas E | ||||||||||
| PMID: | 16179498 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Cancer Ther. 2005 Nov;4(11):1740-6. | ||||||||||
| Title: | The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. | ||||||||||
| Author: | Hsi, Linda C|Xi, Xiaopei|Wu, Yuanqing|Lippman, Scott M | ||||||||||
| PMID: | 16275995 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Res. 2005 Dec 15;65(24):11486-92. | ||||||||||
| Title: | The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. | ||||||||||
| Author: | Shureiqi, Imad|Wu, Yuanqing|Chen, Dongning|Yang, Xiu L|Guan, Baoxiang|Morris, Jeffrey S|Yang, Peiying|Newman, Robert A|Broaddus, Russell|Hamilton, Stanley R|Lynch, Patrick|Levin, Bernard|Fischer, Susan M|Lippman, Scott M | ||||||||||
| PMID: | 16357157 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogene. 2006 Feb 23;25(8):1225-41. | ||||||||||
| Title: | Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. | ||||||||||
| Author: | Zuo, X|Wu, Y|Morris, J S|Stimmel, J B|Leesnitzer, L M|Fischer, S M|Lippman, S M|Shureiqi, I | ||||||||||
| PMID: | 16288226 | ||||||||||
| 22. | |||||||||||
| Journal: | FASEB J. 2007 Mar;21(3):743-53. Epub 2006 Dec 13. | ||||||||||
| Title: | The transcription factor GATA-6 is overexpressed in vivo and contributes to silencing 15-LOX-1 in vitro in human colon cancer. | ||||||||||
| Author: | Shureiqi, Imad|Zuo, Xiangsheng|Broaddus, Russell|Wu, Yuanqing|Guan, Baoxiang|Morris, Jeffrey S|Lippman, Scott M | ||||||||||
| PMID: | 17167069 | ||||||||||
| 23. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2007 Dec;22(12):2324-9. Epub 2007 Jun 7. | ||||||||||
| Title: | The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds. | ||||||||||
| Author: | Yoshinaga, Masahiro|Murao, Hiroyuki|Kitamura, Yosuke|Koga, Koutaro|Tsuruta, Satoru|Igarashi, Hisato|Nakamura, Kazuhiko|Takayanagi, Ryoichi | ||||||||||
| PMID: | 17559385 | ||||||||||
| 24. | |||||||||||
| Journal: | Histopathology. 2007 Oct;51(4):520-7. Epub 2007 Aug 17. | ||||||||||
| Title: | Reversal of expression of 15-lipoxygenase-1 to cyclooxygenase-2 is associated with development of colonic cancer. | ||||||||||
| Author: | Yuri, M|Sasahira, T|Nakai, K|Ishimaru, S|Ohmori, H|Kuniyasu, H | ||||||||||
| PMID: | 17711445 | ||||||||||
| 25. | |||||||||||
| Journal: | FASEB J. 2008 Jun;22(6):1981-92. | ||||||||||
| Title: | 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. | ||||||||||
| Author: | Zuo, Xiangsheng|Shen, Lanlan|Issa, Jean-Pierre|Moy, Ofir|Morris, Jeffrey S|Lippman, Scott M|Shureiqi, Imad | ||||||||||
| PMID: | 18198215 | ||||||||||
| 26. | |||||||||||
| Journal: | J Biol Chem. 2008 Nov 14;283(46):31341-7. | ||||||||||
| Title: | Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells. | ||||||||||
| Author: | Zuo, Xiangsheng|Morris, Jeffrey S|Shureiqi, Imad | ||||||||||
| PMID: | 18799463 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2008 Dec 15;123(12):2741-9. | ||||||||||
| Title: | 15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity. | ||||||||||
| Author: | Zhu, Hong|Glasgow, Wayne|George, Margaret D|Chrysovergis, Kali|Olden, Kenneth|Roberts, John D|Eling, Thomas | ||||||||||
| PMID: | 18785202 | ||||||||||
| 28. | |||||||||||
| Journal: | Bioorg Med Chem. 2008 Apr 15;16(8):4589-93. | ||||||||||
| Title: | Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids. | ||||||||||
| Author: | Russell, Wendy R|Scobbie, Lorraine|Duthie, Garry G|Chesson, Andrew | ||||||||||
| PMID: | 18314336 | ||||||||||
| 29. | |||||||||||
| Journal: | Mol Ther. 2008 May;16(5):886-92. | ||||||||||
| Title: | Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer. | ||||||||||
| Author: | Wu, Yuanqing|Fang, Bingliang|Yang, Xiulan Q|Wang, Li|Chen, Dongning|Krasnykh, Victor|Carter, Bing Z|Morris, Jeffrey S|Shureiqi, Imad | ||||||||||
| PMID: | 18388920 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncogene. 2009 Mar 26;28(12):1496-505. | ||||||||||
| Title: | 15-LOX-1 transcription suppression through the NuRD complex in colon cancer cells. | ||||||||||
| Author: | Zuo, X|Morris, J S|Broaddus, R|Shureiqi, I | ||||||||||
| PMID: | 19198625 | ||||||||||
| 31. | |||||||||||
| Journal: | Curr Mol Med. 2009 Jun;9(5):565-79. | ||||||||||
| Title: | Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer. | ||||||||||
| Author: | Janakiram, Naveena B|Rao, Chinthalapally V | ||||||||||
| PMID: | 19601807 | ||||||||||
| 32. | |||||||||||
| Journal: | Tumour Biol. 2009;30(4):185-99. | ||||||||||
| Title: | 15-lipoxygenase-1 in colorectal cancer: a review. | ||||||||||
| Author: | Bhattacharya, S|Mathew, G|Jayne, D G|Pelengaris, S|Khan, M | ||||||||||
| PMID: | 19752603 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2010 Jul;3(7):829-38. | ||||||||||
| Title: | Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. | ||||||||||
| Author: | Shureiqi, Imad|Chen, Dongning|Day, R Sue|Zuo, Xiangsheng|Hochman, Fredric Lyone|Ross, William A|Cole, Rhonda A|Moy, Ofie|Morris, Jeffrey S|Xiao, Lianchun|Newman, Robert A|Yang, Peiying|Lippman, Scott M | ||||||||||
| PMID: | 20570882 | ||||||||||
| 34. | |||||||||||
| Journal: | J Cell Biochem. 2011 Sep;112(9):2490-501. | ||||||||||
| Title: | 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. | ||||||||||
| Author: | Cimen, I|Astarci, E|Banerjee, S | ||||||||||
| PMID: | 21544861 | ||||||||||
| 35. | |||||||||||
| Journal: | Mol Cancer Ther. 2011 Jul;10(7):1149-60. | ||||||||||
| Title: | Silencing IL-13Ralpha2 promotes glioblastoma cell death via endogenous signaling. | ||||||||||
| Author: | Hsi, Linda C|Kundu, Suman|Palomo, Juan|Xu, Bo|Ficco, Ryan|Vogelbaum, Michael A|Cathcart, Martha K | ||||||||||
| PMID: | 21596889 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2011 Dec;4(12):1961-72. | ||||||||||
| Title: | Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion. | ||||||||||
| Author: | Moussalli, Micheline J|Wu, Yuanqing|Zuo, Xiangsheng|Yang, Xiu L|Wistuba, Ignacio Ivan|Raso, Maria G|Morris, Jeffrey S|Bowser, Jessica L|Minna, John D|Lotan, Reuben|Shureiqi, Imad | ||||||||||
| PMID: | 21881028 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Metastasis Rev. 2011 Dec;30(3-4):481-91. | ||||||||||
| Title: | 15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in? | ||||||||||
| Author: | Il Lee, Sun|Zuo, Xiangsheng|Shureiqi, Imad | ||||||||||
| PMID: | 22037943 | ||||||||||
| 38. | |||||||||||
| Journal: | Genes Nutr. 2013 Jan;8(1):115-26. | ||||||||||
| Title: | PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. | ||||||||||
| Author: | Habermann, Nina|Ulrich, Cornelia M|Lundgreen, Abbie|Makar, Karen W|Poole, Elizabeth M|Caan, Bette|Kulmacz, Richard|Whitton, John|Galbraith, Rachel|Potter, John D|Slattery, Martha L | ||||||||||
| PMID: | 22678777 | ||||||||||
| 39. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2013 May;52(5):437-49. | ||||||||||
| Title: | Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia. | ||||||||||
| Author: | Kleinstein, Sarah E|Heath, Laura|Makar, Karen W|Poole, Elizabeth M|Seufert, Brenna L|Slattery, Martha L|Xiao, Liren|Duggan, David J|Hsu, Li|Curtin, Karen|Koepl, Lisel|Muehling, Jill|Taverna, Darin|Caan, Bette J|Carlson, Christopher S|Potter, John D|Ulrich | ||||||||||
| PMID: | 23404351 | ||||||||||
| 40. | |||||||||||
| Journal: | Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:139-43. | ||||||||||
| Title: | Eicosanoid profiling in colon cancer: emergence of a pattern. | ||||||||||
| Author: | Zuo, Xiangsheng|Shureiqi, Imad | ||||||||||
| PMID: | 22960430 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Med. 2014 Jun;3(3):472-84. | ||||||||||
| Title: | 15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1alpha expression in human colon cancer cells. | ||||||||||
| Author: | Wu, Yuanqing|Mao, Fei|Zuo, Xiangsheng|Moussalli, Micheline J|Elias, Elias|Xu, Weiguo|Shureiqi, Imad | ||||||||||
| PMID: | 24634093 | ||||||||||
| 42. | |||||||||||
| Journal: | Oncotarget. 2015 Feb 20;6(5):2879-88. | ||||||||||
| Title: | 12/15 Lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12-HETE and 13-HODE in animal models. | ||||||||||
| Author: | Chang, Jian|Jiang, Li|Wang, Yinqiu|Yao, Bing|Yang, Shilin|Zhang, Bixiang|Zhang, Ming-Zhi | ||||||||||
| PMID: | 25576922 | ||||||||||
| 43. | |||||||||||
| Journal: | FASEB J. 2015 Jun;29(6):2359-70. | ||||||||||
| Title: | 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. | ||||||||||
| Author: | Mao, Fei|Xu, Min|Zuo, Xiangsheng|Yu, Jiang|Xu, Weiguo|Moussalli, Micheline J|Elias, Elias|Li, Haiyan S|Watowich, Stephanie S|Shureiqi, Imad | ||||||||||
| PMID: | 25713055 | ||||||||||
| 44. | |||||||||||
| Journal: | Daru. 2015 Jul 22;23:36. | ||||||||||
| Title: | Phthalimide analogs as probable 15-lipoxygenase-1 inhibitors: synthesis, biological evaluation and docking studies. | ||||||||||
| Author: | Aliabadi, Alireza|Mohammadi-Farani, Ahmad|Hosseinzadeh, Zeinab|Nadri, Hamid|Moradi, Alireza|Ahmadi, Farahnaz | ||||||||||
| PMID: | 26197788 | ||||||||||
| 45. | |||||||||||
| Journal: | Cell Prolif. 2016 Aug;49(4):448-59. | ||||||||||
| Title: | Interplay between 15-lipoxygenase-1 and metastasis-associated antigen 1 in the metastatic potential of colorectal cancer. | ||||||||||
| Author: | Tuncer, S|Tuncay Cagatay, S|Keskus, A G|Colakoglu, M|Konu, O|Banerjee, S | ||||||||||
| PMID: | 27320813 | ||||||||||
| 46. | |||||||||||
| Journal: | Sci Rep. 2016 Aug 22;6:31826. | ||||||||||
| Title: | Filtrating colorectal cancer associated genes by integrated analyses of global DNA methylation and hydroxymethylation in cancer and normal tissue. | ||||||||||
| Author: | Li, Ming|Gao, Fei|Xia, Yudong|Tang, Yi|Zhao, Wei|Jin, Congcong|Luo, Huijuan|Wang, Junwen|Li, Qingshu|Wang, Yalan | ||||||||||
| PMID: | 27546520 | ||||||||||
| 47. | |||||||||||
| Journal: | Prostaglandins Other Lipid Mediat. 2017 Sep;132:77-83. | ||||||||||
| Title: | ALOX15 as a suppressor of inflammation and cancer: Lost in the link. | ||||||||||
| Author: | Tian, Rui|Zuo, Xiangsheng|Jaoude, Jonathan|Mao, Fei|Colby, Jennifer|Shureiqi, Imad | ||||||||||
| PMID: | 28089732 | ||||||||||
| 48. | |||||||||||
| Journal: | Colorectal Dis. 2017 May;19(5):O115-O125. | ||||||||||
| Title: | Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study. | ||||||||||
| Author: | Alonso, S|Mayol, X|Nonell, L|Salvans, S|Pascual, M|Pera, M | ||||||||||
| PMID: | 28214365 | ||||||||||