Primary Site >> Esophagus Cancer

Gene >> ALDH2

Journal: Cancer Epidemiol Biomarkers Prev. 1996 Feb;5(2):99-102.
Title: Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males.
Author: Yokoyama, A|Muramatsu, T|Ohmori, T|Higuchi, S|Hayashida, M|Ishii, H
PMID: 8850269
Journal: Cancer. 1996 May 15;77(10):1986-90.
Title: Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Ohmori, T|Makuuchi, H|Higuchi, S|Matsushita, S|Yoshino, K|Maruyama, K|Nakano, M|Ishii, H
PMID: 8640660
Journal: Int J Cancer. 1996 Nov 4;68(3):313-6.
Title: Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype.
Author: Yokoyama, A|Ohmori, T|Muramatsu, T|Higuchi, S|Yokoyama, T|Matsushita, S|Matsumoto, M|Maruyama, K|Hayashida, M|Ishii, H
PMID: 8903472
Journal: J Clin Gastroenterol. 1997 Dec;25(4):568-75.
Title: Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility.
Author: Hori, H|Kawano, T|Endo, M|Yuasa, Y
PMID: 9451664
Journal: Carcinogenesis. 1998 Aug;19(8):1383-7.
Title: Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Ohmori, T|Yokoyama, T|Okuyama, K|Takahashi, H|Hasegawa, Y|Higuchi, S|Maruyama, K|Shirakura, K|Ishii, H
PMID: 9744533
Journal: Int J Cancer. 1998 Nov 23;78(5):568-75.
Title: Multifocal accumulation of p53 protein in esophageal carcinoma: evidence for field cancerization.
Author: Tian, D|Feng, Z|Hanley, N M|Setzer, R W|Mumford, J L|DeMarini, D M
PMID: 9808524
Journal: Cancer Epidemiol Biomarkers Prev. 1998 Jun;7(6):473-6.
Title: Short-term follow-up after endoscopic mucosectomy of early esophageal cancer and aldehyde dehydrogenase-2 genotype in Japanese alcoholics.
Author: Yokoyama, A|Ohmori, T|Muramatsu, T|Yokoyama, T|Okuyama, K|Makuuchi, H|Takahashi, H|Higuchi, S|Hayashida, M|Maruyama, K|Ishii, H
PMID: 9641490
Journal: Alcohol Clin Exp Res. 1999 Apr;23(4 Suppl):17S-20S.
Title: Genetic polymorphism of aldehyde dehydrogenase 2 in patients with upper aerodigestive tract cancer.
Author: Tanabe, H|Ohhira, M|Ohtsubo, T|Watari, J|Yokota, K|Kohgo, Y
PMID: 10235272
Journal: Alcohol Clin Exp Res. 1999 Nov;23(11):1705-10.
Title: Alcohol and aldehyde dehydrogenase gene polymorphisms influence susceptibility to esophageal cancer in Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Omori, T|Matsushita, S|Yoshimizu, H|Higuchi, S|Yokoyama, T|Maruyama, K|Ishii, H
PMID: 10591585
Journal: Cancer Lett. 2000 Feb 28;149(1-2):69-76.
Title: Relationship between alcohol drinking, ADH2 and ALDH2 genotypes, and risk for hepatocellular carcinoma in Japanese.
Author: Takeshita, T|Yang, X|Inoue, Y|Sato, S|Morimoto, K
PMID: 10737710
Journal: Am J Gastroenterol. 2000 Oct;95(10):2958-64.
Title: Chinese alcoholic patients with esophageal cancer are genetically different from alcoholics with acute pancreatitis and liver cirrhosis.
Author: Chao, Y C|Wang, L S|Hsieh, T Y|Chu, C W|Chang, F Y|Chu, H C
PMID: 11051375
Journal: Carcinogenesis. 2001 Jun;22(6):913-6.
Title: Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer.
Author: Matsuo, K|Hamajima, N|Shinoda, M|Hatooka, S|Inoue, M|Takezaki, T|Tajima, K
PMID: 11375898
Journal: Asian Pac J Cancer Prev. 2001;2(2):99-107.
Title: Gene-environment Interactions and Polymorphism Studies of Cancer Risk in the Hospital-based Epidemiologic Research Program at Aichi Cancer Center II (HERPACC-II).
Author: Hamajima, Nobuyuki|Matsuo, Keitaro|Saito, Toshiko|Hirose, Kaoru|Inoue, Manami|Takezaki, Toshiro|Kuroishi, Tetsuo|Tajima, Kazuo
PMID: 12718640
Journal: Nihon Arukoru Yakubutsu Igakkai Zasshi. 2001 Dec;36(6):551-66.
Title: [Alcohol and oropharyngolaryngeal and digestive tract cancer].
Author: Yokoyama, A|Omori, T
PMID: 11828713
Journal: Carcinogenesis. 2001 Mar;22(3):433-9.
Title: Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Omori, T|Yokoyama, T|Matsushita, S|Higuchi, S|Maruyama, K|Ishii, H
PMID: 11238183
Journal: Oncol Rep. 2002 Sep-Oct;9(5):1063-8.
Title: Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer.
Author: Watanabe, Seishiro|Sasahara, Katsuyuki|Kinekawa, Fumihiko|Uchida, Naohito|Masaki, Tsutomu|Kurokohchi, Kazutaka|Murota, Masayuki|Touge, Tetsuo|Kawauchi, Kazuyoshi|Oda, Syuji|Kuriyama, Shigeki
PMID: 12168074
Journal: Alcohol Clin Exp Res. 2002 Aug;26(8 Suppl):15S-19S.
Title: Tandem repeat polymorphism of the CYP2E1 gene: an association study with esophageal cancer and lung cancer.
Author: Itoga, Sakae|Nomura, Fumio|Makino, Yasuhiko|Tomonaga, Takeshi|Shimada, Hideaki|Ochiai, Takenori|Iizasa, Toshihiko|Baba, Masayuki|Fujisawa, Takehiko|Harada, Shoji
PMID: 12198369
Journal: Cancer Lett. 2002 Dec 5;186(2):193-9.
Title: Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population.
Author: Boonyaphiphat, Pleumjit|Thongsuksai, Paramee|Sriplung, Hutcha|Puttawibul, Puttisak
PMID: 12213289
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):895-900.
Title: Multiple cancers associated with esophageal and oropharyngolaryngeal squamous cell carcinoma and the aldehyde dehydrogenase-2 genotype in male Japanese drinkers.
Author: Yokoyama, Akira|Watanabe, Hiroshi|Fukuda, Haruhiko|Haneda, Tatsumasa|Kato, Hoichi|Yokoyama, Tetsuji|Muramatsu, Taro|Igaki, Hiroyasu|Tachimori, Yuji
PMID: 12223435
Journal: Carcinogenesis. 2002 Nov;23(11):1851-9.
Title: Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma.
Author: Yokoyama, Akira|Kato, Hoichi|Yokoyama, Tetsuji|Tsujinaka, Toshimasa|Muto, Manabu|Omori, Tai|Haneda, Tatsumasa|Kumagai, Yoshiya|Igaki, Hiroyasu|Yokoyama, Masako|Watanabe, Hiroshi|Fukuda, Haruhiko|Yoshimizu, Haruko
PMID: 12419833
Journal: Cancer Epidemiol Biomarkers Prev. 2003 Nov;12(11 Pt 1):1227-33.
Title: Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men.
Author: Yokoyama, Tetsuji|Yokoyama, Akira|Kato, Hoichi|Tsujinaka, Toshimasa|Muto, Manabu|Omori, Tai|Haneda, Tatsumasa|Kumagai, Yoshiya|Igaki, Hiroyasu|Yokoyama, Masako|Watanabe, Hiroshi|Yoshimizu, Haruko
PMID: 14652286
Journal: Jpn J Clin Oncol. 2003 Mar;33(3):111-21.
Title: Genetic polymorphisms of alcohol and aldehyde dehydrogenases and risk for esophageal and head and neck cancers.
Author: Yokoyama, Akira|Omori, Tai
PMID: 12672787
Journal: Carcinogenesis. 2003 Nov;24(11):1773-8.
Title: Macrocytosis, a new predictor for esophageal squamous cell carcinoma in Japanese alcoholic men.
Author: Yokoyama, Akira|Yokoyama, Tetsuji|Muramatsu, Taro|Omori, Tai|Matsushita, Sachio|Higuchi, Susumu|Maruyama, Katsuya|Ishii, Hiromasa
PMID: 12949054
Journal: Hepatol Res. 2004 Apr;28(4):177-183.
Title: Hepatocellular carcinoma in heavy drinkers with negative markers for viral hepatitis.
Author: Yamagishi, Yoshiyuki|Horie, Yoshinori|Kajihara, Mikio|Konishi, Masahiro|Ebinuma, Hirotoshi|Saito, Hidetsugu|Kato, Shinzo|Yokoyama, Akira|Maruyama, Katsuya|Ishii, Hiromasa
PMID: 15040957
Journal: Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):117S-122S.
Title: Comparative analyses of four different methods of genotyping ALDH2.
Author: Itoga, Sakae|Nanmoku, Toru|Uchimoto, Takayuki|Sunaga, Masahiko|Nezu, Masahiko|Tomonaga, Takeshi|Harada, Shoji|Nomura, Fumio
PMID: 15318097
Journal: Cancer Lett. 2004 Sep 30;213(2):195-202.
Title: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison.
Author: Sepehr, Alireza|Kamangar, Farin|Abnet, Christian C|Fahimi, Saman|Pourshams, Akram|Poustchi, Hossein|Zeinali, Sirous|Sotoudeh, Masood|Islami, Farhad|Nasrollahzadeh, Dariush|Malekzadeh, Reza|Taylor, Philip R|Dawsey, Sanford M
PMID: 15327835
Journal: Pancreas. 2005 Mar;30(2):95-8.
Title: Inactive aldehyde dehydrogenase-2 increased the risk of pancreatic cancer among smokers in a Japanese male population.
Author: Miyasaka, Kyoko|Kawanami, Takako|Shimokata, Hiroshi|Ohta, Shigeo|Funakoshi, Akihiro
PMID: 15714130
Journal: Front Biosci. 2005 Sep 1;10:2319-24.
Title: Expression of aldehyde dehydrogenase 2 in the normal esophageal epithelium and alcohol consumption in patients with esophageal cancer.
Author: Morita, Masaru|Oyama, Tsunehiro|Kagawa, Norio|Nakata, Shoji|Ono, Kenji|Sugaya, Masakazu|Uramoto, Hidetaka|Yoshimatsu, Takashi|Hanagiri, Takeshi|Sugio, Kenji|Kakeji, Yoshihiro|Yasumoto, Kosei
PMID: 15970497
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1967-71.
Title: Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach.
Author: Lewis, Sarah J|Smith, George Davey
PMID: 16103445
Journal: World J Gastroenterol. 2005 Sep 7;11(33):5103-8.
Title: Relationship between genetic polymorphisms of alcohol and aldehyde dehydrogenases and esophageal squamous cell carcinoma risk in males.
Author: Wu, Chia-Fang|Wu, Deng-Chyang|Hsu, Hon-Ki|Kao, Ein-Long|Lee, Jang-Ming|Lin, Cheng-Chieh|Wu, Ming-Tsang
PMID: 16127737
Journal: Asian Pac J Cancer Prev. 2005 Jul-Sep;6(3):256-62.
Title: Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions.
Author: Yang, Chun-Xia|Matsuo, Keitaro|Ito, Hidemi|Hirose, Kaoru|Wakai, Kenji|Saito, Toshiko|Shinoda, Masayuki|Hatooka, Shunzo|Mizutani, Kazuko|Tajima, Kazuo
PMID: 16235983
Journal: World J Gastroenterol. 2005 Oct 14;11(38):6043-8.
Title: CD14 promoter polymorphism in Chinese alcoholic patients with cirrhosis of liver and acute pancreatitis.
Author: Chao, You-Chen|Chu, Heng-Cheng|Chang, Wei-Kuo|Huang, Hsin-Hung|Hsieh, Tsai-Yuan
PMID: 16273622
Journal: J Hum Genet. 2006;51(2):104-11. Epub 2005 Dec 20.
Title: ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers.
Author: Yamada, Yuichi|Imai, Tsunehiko|Ishizaki, Masao|Honda, Ryumon
PMID: 16365683
Journal: Int J Cancer. 2006 Dec 15;119(12):2827-31.
Title: Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks.
Author: Chen, Yun-Ju|Chen, Chu|Wu, Deng-Chyang|Lee, Chien-Hung|Wu, Chen-I|Lee, Jang-Ming|Goan, Yih-Gang|Huang, Shu-Pin|Lin, Cheng-Chieh|Li, Tsai-Chung|Chou, Yi-Pin|Wu, Ming-Tsang
PMID: 17036331
Journal: Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):696-703.
Title: Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract.
Author: Hashibe, Mia|Boffetta, Paolo|Zaridze, David|Shangina, Oxana|Szeszenia-Dabrowska, Neonila|Mates, Dana|Janout, Vladimir|Fabianova, Eleonora|Bencko, Vladimir|Moullan, Norman|Chabrier, Amelie|Hung, Rayjean|Hall, Janet|Canzian, Federico|Brennan, Paul
PMID: 16614111
Journal: Alcohol Clin Exp Res. 2006 Mar;30(3):491-500.
Title: Esophageal squamous cell carcinoma and aldehyde dehydrogenase-2 genotypes in Japanese females.
Author: Yokoyama, Akira|Kato, Hoichi|Yokoyama, Tetsuji|Igaki, Hiroyasu|Tsujinaka, Toshimasa|Muto, Manabu|Omori, Tai|Kumagai, Yoshiya|Yokoyama, Masako|Watanabe, Hiroshi
PMID: 16499490
Journal: J Gastroenterol Hepatol. 2007 Feb;22(2):210-7.
Title: Helicobacter pylori, chronic atrophic gastritis, inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive tract cancers and the risk for gastric cancer in alcoholic Japanese men.
Author: Yokoyama, Akira|Yokoyama, Tetsuji|Omori, Tai|Matsushita, Sachio|Mizukami, Takeshi|Takahashi, Hisao|Higuchi, Susumu|Maruyama, Katsuya|Ishii, Hiromasa|Hibi, Toshifumi
PMID: 17295873
Journal: Int J Cancer. 2007 Oct 15;121(8):1643-58.
Title: Genetic polymorphisms and esophageal cancer risk.
Author: Hiyama, Toru|Yoshihara, Masaharu|Tanaka, Shinji|Chayama, Kazuaki
PMID: 17674367
Journal: World J Gastroenterol. 2007 Nov 21;13(43):5760-4.
Title: Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China.
Author: Yang, Shu-Juan|Wang, Hua-Yu|Li, Xiao-Qing|Du, Hui-Zhang|Zheng, Can-Jie|Chen, Huai-Gong|Mu, Xiao-Yan|Yang, Chun-Xia
PMID: 17963305
Journal: World J Gastroenterol. 2008 Mar 7;14(9):1444-9.
Title: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males.
Author: Guo, Yan-Mei|Wang, Qin|Liu, Yan-Zhen|Chen, Huei-Min|Qi, Zhi|Guo, Qing-Hong
PMID: 18322963
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3097-102.
Title: Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population.
Author: Oze, Isao|Matsuo, Keitaro|Suzuki, Takeshi|Kawase, Takakazu|Watanabe, Miki|Hiraki, Akio|Ito, Hidemi|Hosono, Satoyo|Ozawa, Taijiro|Hatooka, Shunzo|Yatabe, Yasuhi|Hasegawa, Yasuhisa|Shinoda, Masayuki|Kiura, Katsuyuki|Tajima, Kazuo|Tanimoto, Mitsune|Tanaka, H
PMID: 19861527
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2009 May;30(5):455-8.
Title: [Genetic polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 associated with the susceptibility on esophageal cancer].
Author: Ding, Jian-hua|Li, Su-ping|Cao, Hai-xia|Wu, Jian-zhong|Gao, Chang-ming|Su, Ping|Liu, Yan-ting|Zhou, Jian-nong|Chang, Jun|Yao, Gen-hong
PMID: 19799139
Journal: Gastroenterology. 2009 Nov;137(5):1768-75.
Title: Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Author: Cui, Ri|Kamatani, Yoichiro|Takahashi, Atsushi|Usami, Masayuki|Hosono, Naoya|Kawaguchi, Takahisa|Tsunoda, Tatsuhiko|Kamatani, Naoyuki|Kubo, Michiaki|Nakamura, Yusuke|Matsuda, Koichi
PMID: 19698717
Journal: World J Gastroenterol. 2009 May 21;15(19):2395-400.
Title: Polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males.
Author: Ding, Jian-Hua|Li, Su-Ping|Cao, Hai-Xia|Wu, Jian-Zhong|Gao, Chang-Ming|Su, Ping|Liu, Yan-Ting|Zhou, Jian-Nong|Chang, Jun|Yao, Gen-Hong
PMID: 19452585
Journal: Ann Hum Genet. 2009 May;73(Pt 3):335-45.
Title: Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant.
Author: Li, Hui|Borinskaya, Svetlana|Yoshimura, Kimio|Kal'ina, Nina|Marusin, Andrey|Stepanov, Vadim A|Qin, Zhendong|Khaliq, Shagufta|Lee, Mi-Young|Yang, Yajun|Mohyuddin, Aisha|Gurwitz, David|Mehdi, Syed Qasim|Rogaev, Evgeny|Jin, Li|Yankovsky, Nikolay K|Kidd, Judi
PMID: 19456322
Journal: Ann Hum Genet. 2009 May;73(Pt 3):335-45.
Title: Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant.
Author: Li, Hui|Borinskaya, Svetlana|Yoshimura, Kimio|Kal'ina, Nina|Marusin, Andrey|Stepanov, Vadim A|Qin, Zhendong|Khaliq, Shagufta|Lee, Mi-Young|Yang, Yajun|Mohyuddin, Aisha|Gurwitz, David|Mehdi, Syed Qasim|Rogaev, Evgeny|Jin, Li|Yankovsky, Nikolay K|Kidd, Judi
PMID: 9699791
Journal: J Hum Genet. 2010 Feb;55(2):97-102.
Title: Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk for esophageal cancer in a Chinese population.
Author: Ding, Jian-hua|Li, Su-ping|Cao, Hai-xia|Wu, Jian-zhong|Gao, Chang-ming|Liu, Yan-ting|Zhou, Jian-nong|Chang, Jun|Yao, Geng-hong
PMID: 20010786
Journal: Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S120-6.
Title: Association of aldehyde dehydrogenase 2 gene polymorphism with pancreatic cancer but not colon cancer.
Author: Miyasaka, Kyoko|Hosoya, Hiroko|Tanaka, Yasuo|Uegaki, Satoko|Kino, Kenji|Shimokata, Hiroshi|Kawanami, Takako|Funakoshi, Akihiro
PMID: 20590827
Journal: World J Gastroenterol. 2010 Jul 21;16(27):3445-9.
Title: Association of genetic polymorphisms of aldehyde dehydrogenase-2 with esophageal squamous cell dysplasia.
Author: Zhou, Ying-Zhi|Diao, Yu-Tao|Li, Hao|Li, Hui-Qing|Ma, Qing|Cui, Jia
PMID: 20632450
Journal: World J Gastroenterol. 2010 Sep 7;16(33):4210-20.
Title: Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis.
Author: Yang, Shu-Juan|Yokoyama, Akira|Yokoyama, Tetsuji|Huang, Yu-Chuan|Wu, Si-Ying|Shao, Ying|Niu, Jin|Wang, Jie|Liu, Yu|Zhou, Xiao-Qiao|Yang, Chun-Xia
PMID: 20806441
Journal: PLoS One. 2010 Oct 27;5(10):e13679.
Title: ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis.
Author: Zhang, Guohong|Mai, Ruiqin|Huang, Bo
PMID: 21048924
Journal: World J Gastroenterol. 2010 Dec 21;16(47):6020-5.
Title: Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China.
Author: Zhang, Guo-Hong|Mai, Rui-Qin|Huang, Bo
PMID: 21157980
Journal: Asian Pac J Cancer Prev. 2011;12(8):2065-8.
Title: Esophageal squamous cell carcinoma and ALDH2 and ADH1B polymorphisms in Chinese females.
Author: Wang, Yulin|Ji, Runli|Wei, Xu|Gu, Lili|Chen, Linyan|Rong, Yamei|Wang, Ruitao|Zhang, Zhengyun|Liu, Baiqing|Xia, Shihai
PMID: 22292652
Journal: Asian Pac J Cancer Prev. 2011;12(10):2623-7.
Title: Meta-analysis of ALDH2 variants and esophageal cancer in Asians.
Author: Fang, Ping|Jiao, Shunchang|Zhang, Xin|Liu, Zhefeng|Wang, Hongzhen|Gao, Yan|Luo, Hao|Chen, Tao|Shi, Li
PMID: 22320964
Journal: BMC Gastroenterol. 2011 Jun 14;11:74.
Title: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County.
Author: Li, Qing Da|Li, Hao|Wang, Mei Shu|Diao, Tao Yu|Zhou, Zhi Ying|Fang, Qiang Xue|Yang, Fang Yan|Li, Qing Hui
PMID: 21672255
Journal: Cancer Lett. 2011 Sep 1;308(1):112-7.
Title: p53 protein accumulation, iodine-unstained lesions, and alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese alcoholic men with esophageal dysplasia.
Author: Yokoyama, Akira|Tanaka, Yoichi|Yokoyama, Tetsuji|Mizukami, Takeshi|Matsui, Toshifumi|Maruyama, Katsuya|Omori, Tai
PMID: 21601984
Journal: Gan To Kagaku Ryoho. 2012 Jan;39(1):8-12.
Title: [Present and future state of cancer screening for esophageal cancer and gastric cancer].
Author: Nakashima, Hirotaka|Nagahama, Ryuji|Yoshida, Misao
PMID: 22241346
Journal: Biomarkers. 2012 May;17(3):269-74.
Title: The effect of ethanol on the formation of N2-ethylidene-dG adducts in mice: implications for alcohol-related carcinogenicity of the oral cavity and esophagus.
Author: Yu, Hsu-Sheng|Oyama, Tsunehiro|Matsuda, Tomonari|Isse, Toyohi|Yamaguchi, Tetsunosuke|Tanaka, Masayuki|Tsuji, Mayumi|Kawamoto, Toshihiro
PMID: 22416850
Journal: Cancer Sci. 2012 Sep;103(9):1651-5.
Title: Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics.
Author: Yukawa, Yoshiyuki|Muto, Manabu|Hori, Kimiko|Nagayoshi, Haruna|Yokoyama, Akira|Chiba, Tsutomu|Matsuda, Tomonari
PMID: 22703580
Journal: Exp Ther Med. 2012 Jul;4(1):135-140. Epub 2012 Apr 17.
Title: A variant allele of ADH1B and ALDH2, is associated with the risk of esophageal cancer.
Author: Gu, Haiyong|Gong, Dingxu|Ding, Guowen|Zhang, Wenbo|Liu, Chao|Jiang, Pengcheng|Chen, Suocheng|Chen, Yijang
PMID: 23060937
Journal: Alcohol Res. 2012;34(3):274-81.
Title: Identifying genetic variation for alcohol dependence.
Author: Agrawal, Arpana|Bierut, Laura J
PMID: 23134043
Journal: Alcohol Res. 2012;34(3):339-44.
Title: Genes encoding enzymes involved in ethanol metabolism.
Author: Hurley, Thomas D|Edenberg, Howard J
PMID: 23134050
Journal: Wei Sheng Yan Jiu. 2012 Sep;41(5):723-9.
Title: [Genetic polymorphisms of ADH1B and ALDH-2 associated with risk of esophageal cancer: a meta-analysis].
Author: Duan, Fujiao|Song, Chunhua|Cui, Shuli|Wang, Longzhi|Zhen, Qian|Qu, Honghong|Wang, Peng|Wang, Kaijuan|Zhang, Jianying|Dai, Liping
PMID: 23213683
Journal: J Hum Genet. 2013 Nov;58(11):742-8.
Title: Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study.
Author: Dura, Polat|Berkers, Tineke|van Veen, Elke M|Salomon, Jody|te Morsche, Rene H M|Roelofs, Hennie M J|Kristinsson, Jon O|Wobbes, Theo|Witteman, Ben J M|Tan, Adriaan C I T L|Drenth, Joost P H|Peters, Wilbert H M
PMID: 24048263
Journal: Dis Esophagus. 2013 Feb-Mar;26(2):148-53.
Title: A health-risk appraisal model and endoscopic mass screening for esophageal cancer in Japanese men.
Author: Yokoyama, A|Oda, J|Iriguchi, Y|Kumagai, Y|Okamura, Y|Matsuoka, M|Mizukami, T|Yokoyama, T
PMID: 22458712
Journal: Int J Cancer. 2013 Apr 15;132(8):1868-77.
Title: Single nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: a population-based case-control study in China.
Author: Wu, Ming|Chang, Shen-Chih|Kampman, Ellen|Yang, Jie|Wang, Xu-Shan|Gu, Xiao-Ping|Han, Ren-Qiang|Liu, Ai-Min|Wallar, Gina|Zhou, Jin-Yi|Kok, Frans J|Zhao, Jin-Kou|Zhang, Zuo-Feng
PMID: 22930414
Journal: Dis Esophagus. 2014 Jul;27(5):493-503.
Title: Tag single nucleotide polymorphisms of alcohol-metabolizing enzymes modify the risk of upper aerodigestive tract cancers: HapMap database analysis.
Author: Chung, C-S|Lee, Y-C|Liou, J-M|Wang, C-P|Ko, J-Y|Lee, J-M|Wu, M-S|Wang, H-P
PMID: 23088731
Journal: Int J Cancer. 2014 Feb 15;134(4):747-54.
Title: Advances in cancer epidemiology in Japan.
Author: Tanaka, Hideo
PMID: 24105756
Journal: Alcohol Clin Exp Res. 2014 May;38(5):1237-46.
Title: Macrocytosis, macrocytic anemia, and genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 in Japanese alcoholic men.
Author: Yokoyama, Akira|Yokoyama, Tetsuji|Brooks, Philip J|Mizukami, Takeshi|Matsui, Toshifumi|Kimura, Mitsuru|Matsushita, Sachio|Higuchi, Susumu|Maruyama, Katsuya
PMID: 24588059
Journal: PLoS One. 2014 Oct 22;9(10):e109235.
Title: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Author: Chang, Shen-Chih|Chang, Po-Yin|Butler, Brendan|Goldstein, Binh Y|Mu, Lina|Cai, Lin|You, Nai-Chieh Y|Baecker, Aileen|Yu, Shun-Zhang|Heber, David|Lu, Qing-Yi|Li, Liming|Greenland, Sander|Zhang, Zuo-Feng
PMID: 25337902
Journal: Annu Rev Pharmacol Toxicol. 2015;55:107-27.
Title: A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant.
Author: Gross, Eric R|Zambelli, Vanessa O|Small, Bryce A|Ferreira, Julio C B|Chen, Che-Hong|Mochly-Rosen, Daria
PMID: 25292432
Journal: Adv Exp Med Biol. 2015;815:41-58.
Title: Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking.
Author: Eriksson, C J Peter
PMID: 25427900
Journal: PLoS One. 2015 Feb 13;10(2):e0117173.
Title: Association between Glu504Lys polymorphism of ALDH2 gene and cancer risk: a meta-analysis.
Author: Cai, Qiang|Wu, Jian|Cai, Qu|Chen, Er-Zhen|Jiang, Zhao-Yan
PMID: 25680115
Journal: PLoS One. 2015 Apr 1;10(4):e0120397.
Title: Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.
Author: Maejima, Ryuhei|Iijima, Katsunori|Kaihovaara, Pertti|Hatta, Waku|Koike, Tomoyuki|Imatani, Akira|Shimosegawa, Tooru|Salaspuro, Mikko
PMID: 25831092
Journal: Onco Targets Ther. 2015 Mar 23;8:649-59.
Title: Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies.
Author: Zhao, Tingting|Wang, Chun|Shen, Lili|Gu, Dongying|Xu, Zhi|Zhang, Xunlei|Xu, Yong|Chen, Jinfei
PMID: 25848305
Journal: Life Sci. 2016 Feb 15;147:59-66.
Title: ALDH2 gene polymorphism in different types of cancers and its clinical significance.
Author: Li, Rui|Zhao, Zihan|Sun, Mingyang|Luo, Jiachi|Xiao, Yechen
PMID: 26804999
Journal: Gastroenterology. 2016 May;150(5):1171-1182.
Title: Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.
Author: Sawada, Genta|Niida, Atsushi|Uchi, Ryutaro|Hirata, Hidenari|Shimamura, Teppei|Suzuki, Yutaka|Shiraishi, Yuichi|Chiba, Kenichi|Imoto, Seiya|Takahashi, Yusuke|Iwaya, Takeshi|Sudo, Tomoya|Hayashi, Tomoatsu|Takai, Hiroki|Kawasaki, Yoshihiro|Matsukawa, Takashi
PMID: 26873401
Journal: Jpn J Clin Oncol. 2017 Apr 1;47(4):306-312.
Title: Recovery from anemia and leukocytopenia after abstinence in Japanese alcoholic men and their genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2.
Author: Yokoyama, Akira|Brooks, Philip J|Yokoyama, Tetsuji|Mizukami, Takeshi|Shiba, Shunsuke|Nakamoto, Nobuhiro|Maruyama, Katsuya
PMID: 28158658
Journal: J Biomed Sci. 2017 Mar 3;24(1):19.
Title: ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective.
Author: Chang, Jeffrey S|Hsiao, Jenn-Ren|Chen, Che-Hong
PMID: 28253921
Journal: PLoS One. 2017 Apr 6;12(4):e0175182.
Title: Alcohol abstinence and risk assessment for second esophageal cancer in Japanese men after mucosectomy for early esophageal cancer.
Author: Yokoyama, Akira|Katada, Chikatoshi|Yokoyama, Tetsuji|Yano, Tomonori|Kaneko, Kazuhiro|Oda, Ichiro|Shimizu, Yuichi|Doyama, Hisashi|Koike, Tomoyuki|Takizawa, Kohei|Hirao, Motohiro|Okada, Hiroyuki|Yoshii, Takako|Konishi, Kazuo|Yamanouchi, Takenori|Tsuda, Taka
PMID: 28384229
Journal: Medicine (Baltimore). 2017 Apr;96(16):e6111.
Title: Association between ALDH2 Glu487Lys polymorphism and the risk of esophageal cancer.
Author: Liu, Kang|Song, Guiqin|Zhu, Xiaoyan|Yang, Xiaolin|Shen, Yuewu|Wang, Wan|Shi, Guidong|Li, Qing|Duan, Yi|Zhao, Yunxia|Feng, Gang
PMID: 28422823
Journal: BMC Res Notes. 2017 Nov 2;10(1):548.
Title: Limitations of lymphoblastoid cell lines for functional analysis of SNPs.
Author: Pathak, Hansi|Frieling, Helge|Rhein, Mathias|Burkert, Alexandra
PMID: 29096698
Journal: Jpn J Clin Oncol. 2017 Dec 1;47(12):1123-1128.
Title: Facial flushing after alcohol intake as a predictor for a high risk of synchronous or metachronous cancer of the upper gastrointestinal tract.
Author: Harada, Hiroyuki|Shinohara, Shogo|Takebayashi, Shinji|Kikuchi, Masahiro|Fujiwara, Keizo|Michida, Tetsuhiko|Yamamoto, Ryosuke|Hayashi, Kazuki|Saida, Koji|Naito, Yasushi
PMID: 29136221
Journal: J Clin Lab Anal. 2018 Feb;32(2).
Title: Correlations of ALDH2 rs671 and C12orf30 rs4767364 polymorphisms with increased risk and prognosis of esophageal squamous cell carcinoma in the Kazak and Han populations in Xinjiang province.
Author: Liu, Pan|Zhao, Hua-Rong|Li, Fang|Zhang, Lei|Zhang, Hua|Wang, Wen-Ran|Mao, Rui|Su, Wei-Peng|Zhang, Yang|Bao, Yong-Xing
PMID: 28464297
Journal: J Gastroenterol. 2018 Oct;53(10):1120-1130.
Title: Risk assessment of metachronous squamous cell carcinoma after endoscopic resection for esophageal carcinoma based on the genetic polymorphisms of alcoholdehydrogense-1B aldehyde dehydrogenase-2: temperance reduces the risk.
Author: Abiko, Satoshi|Shimizu, Yuichi|Miyamoto, Shuichi|Ishikawa, Marin|Matsuda, Kana|Tsuda, Momoko|Mizushima, Takeshi|Yamamoto, Keiko|Ono, Shoko|Kudo, Takahiko|Ono, Kota|Sakamoto, Naoya
PMID: 29423536
Journal: Int J Cancer. 2018 Apr 29.
Title: Association of low-activity ALDH2 and alcohol consumption with risk of esophageal cancer in Chinese adults: A population-based cohort study.
Author: Yu, Canqing|Guo, Yu|Bian, Zheng|Yang, Ling|Millwood, Iona Y|Walters, Robin G|Chen, Yiping|Chen, Yan|Zhang, Xi|Lei, Yulong|Chen, Junshi|Chen, Zhengming|Lv, Jun|Li, Liming
PMID: 29707772
Journal: J Hum Genet. 2018 Sep 10. pii: 10.1038/s10038-018-0501-4.
Title: Gastric cancer may share genetic predisposition with esophageal squamous cell carcinoma in Chinese populations.
Author: Yao, Linhua|Yu, Fei|Mao, Yingying|Wang, Tianpei|Qi, Qi|Ding, Hui|Wang, Jinchen|Ma, Hongxia|Dai, Juncheng|Zhang, Guoxin|Jin, Guangfu
PMID: 30202044