Primary Site >> Esophagus Cancer
Gene >> ALDH2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics. PMID: 8640660 Ref: Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males. PMID: 8850269 Ref: Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype. PMID: 8903472 |
Ref: Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility. PMID: 9451664 |
Ref: Short-term follow-up after endoscopic mucosectomy of early esophageal cancer and aldehyde dehydrogenase-2 genotype in Japanese alcoholics. PMID: 9641490 Ref: Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. PMID: 9744533 Ref: Multifocal accumulation of p53 protein in esophageal carcinoma: evidence for field cancerization. PMID: 9808524 |
Ref: Genetic polymorphism of aldehyde dehydrogenase 2 in patients with upper aerodigestive tract cancer. PMID: 10235272 Ref: Alcohol and aldehyde dehydrogenase gene polymorphisms influence susceptibility to esophageal cancer in Japanese alcoholics. PMID: 10591585 |
Ref: Relationship between alcohol drinking, ADH2 and ALDH2 genotypes, and risk for hepatocellular carcinoma in Japanese. PMID: 10737710 Ref: Chinese alcoholic patients with esophageal cancer are genetically different from alcoholics with acute pancreatitis and liver cirrhosis. PMID: 11051375 |
Ref: Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. PMID: 11238183 Ref: Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer. PMID: 11375898 Ref: [Alcohol and oropharyngolaryngeal and digestive tract cancer]. PMID: 11828713 Ref: Gene-environment Interactions and Polymorphism Studies of Cancer Risk in the Hospital-based Epidemiologic Research Program at Aichi Cancer Center II (HERPACC-II). PMID: 12718640 |
Ref: Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer. PMID: 12168074 Ref: Tandem repeat polymorphism of the CYP2E1 gene: an association study with esophageal cancer and lung cancer. PMID: 12198369 Ref: Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population. PMID: 12213289 Ref: Multiple cancers associated with esophageal and oropharyngolaryngeal squamous cell carcinoma and the aldehyde dehydrogenase-2 genotype in male Japanese drinkers. PMID: 12223435 Ref: Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma. PMID: 12419833 |
Ref: Genetic polymorphisms of alcohol and aldehyde dehydrogenases and risk for esophageal and head and neck cancers. PMID: 12672787 Ref: Macrocytosis, a new predictor for esophageal squamous cell carcinoma in Japanese alcoholic men. PMID: 12949054 Ref: Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men. PMID: 14652286 |
Ref: Hepatocellular carcinoma in heavy drinkers with negative markers for viral hepatitis. PMID: 15040957 Ref: Comparative analyses of four different methods of genotyping ALDH2. PMID: 15318097 Ref: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison. PMID: 15327835 |
Ref: Inactive aldehyde dehydrogenase-2 increased the risk of pancreatic cancer among smokers in a Japanese male population. PMID: 15714130 Ref: Expression of aldehyde dehydrogenase 2 in the normal esophageal epithelium and alcohol consumption in patients with esophageal cancer. PMID: 15970497 Ref: Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. PMID: 16103445 Ref: Relationship between genetic polymorphisms of alcohol and aldehyde dehydrogenases and esophageal squamous cell carcinoma risk in males. PMID: 16127737 Ref: Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions. PMID: 16235983 Ref: CD14 promoter polymorphism in Chinese alcoholic patients with cirrhosis of liver and acute pancreatitis. PMID: 16273622 |
Ref: ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers. PMID: 16365683 Ref: Esophageal squamous cell carcinoma and aldehyde dehydrogenase-2 genotypes in Japanese females. PMID: 16499490 Ref: Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. PMID: 16614111 Ref: Interactive effects of lifetime alcohol consumption and alcohol and aldehyde dehydrogenase polymorphisms on esophageal cancer risks. PMID: 17036331 |
Ref: Helicobacter pylori, chronic atrophic gastritis, inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive tract cancers and the risk for gastric cancer in alcoholic Japanese men. PMID: 17295873 Ref: Genetic polymorphisms and esophageal cancer risk. PMID: 17674367 Ref: Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China. PMID: 17963305 |
Ref: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. PMID: 18322963 |
Ref: Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. PMID: 9699791 Ref: Polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males. PMID: 19452585 Ref: Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. PMID: 19456322 Ref: Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. PMID: 19698717 Ref: [Genetic polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 associated with the susceptibility on esophageal cancer]. PMID: 19799139 Ref: Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. PMID: 19861527 |
Ref: Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk for esophageal cancer in a Chinese population. PMID: 20010786 Ref: Association of aldehyde dehydrogenase 2 gene polymorphism with pancreatic cancer but not colon cancer. PMID: 20590827 Ref: Association of genetic polymorphisms of aldehyde dehydrogenase-2 with esophageal squamous cell dysplasia. PMID: 20632450 Ref: Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis. PMID: 20806441 Ref: ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis. PMID: 21048924 Ref: Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China. PMID: 21157980 |
Ref: p53 protein accumulation, iodine-unstained lesions, and alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese alcoholic men with esophageal dysplasia. PMID: 21601984 Ref: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County. PMID: 21672255 Ref: Esophageal squamous cell carcinoma and ALDH2 and ADH1B polymorphisms in Chinese females. PMID: 22292652 Ref: Meta-analysis of ALDH2 variants and esophageal cancer in Asians. PMID: 22320964 |
Ref: [Present and future state of cancer screening for esophageal cancer and gastric cancer]. PMID: 22241346 Ref: The effect of ethanol on the formation of N2-ethylidene-dG adducts in mice: implications for alcohol-related carcinogenicity of the oral cavity and esophagus. PMID: 22416850 Ref: Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics. PMID: 22703580 Ref: A variant allele of ADH1B and ALDH2, is associated with the risk of esophageal cancer. PMID: 23060937 Ref: Identifying genetic variation for alcohol dependence. PMID: 23134043 Ref: Genes encoding enzymes involved in ethanol metabolism. PMID: 23134050 Ref: [Genetic polymorphisms of ADH1B and ALDH-2 associated with risk of esophageal cancer: a meta-analysis]. PMID: 23213683 |
Ref: A health-risk appraisal model and endoscopic mass screening for esophageal cancer in Japanese men. PMID: 22458712 Ref: Single nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: a population-based case-control study in China. PMID: 22930414 Ref: Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study. PMID: 24048263 |
Ref: Tag single nucleotide polymorphisms of alcohol-metabolizing enzymes modify the risk of upper aerodigestive tract cancers: HapMap database analysis. PMID: 23088731 Ref: Advances in cancer epidemiology in Japan. PMID: 24105756 Ref: Macrocytosis, macrocytic anemia, and genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 in Japanese alcoholic men. PMID: 24588059 Ref: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. PMID: 25337902 |
Ref: A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant. PMID: 25292432 Ref: Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking. PMID: 25427900 Ref: Association between Glu504Lys polymorphism of ALDH2 gene and cancer risk: a meta-analysis. PMID: 25680115 Ref: Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration. PMID: 25831092 Ref: Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies. PMID: 25848305 |
Ref: ALDH2 gene polymorphism in different types of cancers and its clinical significance. PMID: 26804999 Ref: Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. PMID: 26873401 |
Ref: Recovery from anemia and leukocytopenia after abstinence in Japanese alcoholic men and their genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2. PMID: 28158658 Ref: ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective. PMID: 28253921 Ref: Alcohol abstinence and risk assessment for second esophageal cancer in Japanese men after mucosectomy for early esophageal cancer. PMID: 28384229 Ref: Association between ALDH2 Glu487Lys polymorphism and the risk of esophageal cancer. PMID: 28422823 Ref: Limitations of lymphoblastoid cell lines for functional analysis of SNPs. PMID: 29096698 Ref: Facial flushing after alcohol intake as a predictor for a high risk of synchronous or metachronous cancer of the upper gastrointestinal tract. PMID: 29136221 |
Ref: Correlations of ALDH2 rs671 and C12orf30 rs4767364 polymorphisms with increased risk and prognosis of esophageal squamous cell carcinoma in the Kazak and Han populations in Xinjiang province. PMID: 28464297 Ref: Risk assessment of metachronous squamous cell carcinoma after endoscopic resection for esophageal carcinoma based on the genetic polymorphisms of alcoholdehydrogense-1B aldehyde dehydrogenase-2: temperance reduces the risk. PMID: 29423536 Ref: Association of low-activity ALDH2 and alcohol consumption with risk of esophageal cancer in Chinese adults: A population-based cohort study. PMID: 29707772 Ref: Gastric cancer may share genetic predisposition with esophageal squamous cell carcinoma in Chinese populations. PMID: 30202044 |