Primary Site >> Colorectal Cancer

Gene >> ALDH1A1

Journal: Alcohol Clin Exp Res. 1994 Oct;18(5):1256-60.
Title: Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: no gender and age differences.
Author: Yin, S J|Liao, C S|Lee, Y C|Wu, C W|Jao, S W
PMID: 7847616
Journal: Acta Pol Pharm. 2005 Nov-Dec;62(6):427-33.
Title: Activities of cytosolic aldehyde dehydrogenase isozymes in colon cancer: determination using selective, fluorimetric assays.
Author: Wroczynski, Piotr|Nowak, Marzena|Wierzchowski, Jacek|Szubert, Artur|Polanski, Jerzy
PMID: 16583981
Journal: PLoS One. 2008 Jun 18;3(6):e2428.
Title: Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy.
Author: Dylla, Scott J|Beviglia, Lucia|Park, In-Kyung|Chartier, Cecile|Raval, Janak|Ngan, Lucy|Pickell, Kellie|Aguilar, Jorge|Lazetic, Sasha|Smith-Berdan, Stephanie|Clarke, Michael F|Hoey, Tim|Lewicki, John|Gurney, Austin L
PMID: 18560594
Journal: Cancer Res. 2009 Apr 15;69(8):3382-9.
Title: Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.
Author: Huang, Emina H|Hynes, Mark J|Zhang, Tao|Ginestier, Christophe|Dontu, Gabriela|Appelman, Henry|Fields, Jeremy Z|Wicha, Max S|Boman, Bruce M
PMID: 19336570
Journal: Biochem Biophys Res Commun. 2009 Jul 31;385(3):430-3.
Title: Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts.
Author: Levi, Edi|Misra, Sandhya|Du, Jianhua|Patel, Bhaumik B|Majumdar, Adhip P N
PMID: 19465005
Journal: World J Gastroenterol. 2010 Feb 14;16(6):732-9.
Title: ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients.
Author: Hostettler, Lsabel|Zlobec, Inti|Terracciano, Luigi|Lugli, Alessandro
PMID: 20135722
Journal: PLoS One. 2010 Apr 21;5(4):e10277.
Title: Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers.
Author: Deng, Shan|Yang, Xiaojun|Lassus, Heini|Liang, Shun|Kaur, Sippy|Ye, Qunrui|Li, Chunsheng|Wang, Li-Ping|Roby, Katherine F|Orsulic, Sandra|Connolly, Denise C|Zhang, Youcheng|Montone, Kathleen|Butzow, Ralf|Coukos, George|Zhang, Lin
PMID: 20422001
Journal: Br J Cancer. 2010 Jul 27;103(3):382-90.
Title: Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer.
Author: Lugli, A|Iezzi, G|Hostettler, I|Muraro, M G|Mele, V|Tornillo, L|Carafa, V|Spagnoli, G|Terracciano, L|Zlobec, I
PMID: 20606680
Journal: J Ovarian Res. 2010 Dec 22;3:28.
Title: Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors.
Author: Penumatsa, Krishna|Edassery, Seby L|Barua, Animesh|Bradaric, Michael J|Luborsky, Judith L
PMID: 21176222
Journal: Front Biosci (Landmark Ed). 2011 Jan 1;16:1651-62.
Title: Colon cancer stem cells: implications in carcinogenesis.
Author: Sanders, Matthew A|Majumdar, Adhip P N
PMID: 21196254
Journal: Biochem Biophys Res Commun. 2011 Feb 11;405(2):173-9.
Title: Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer.
Author: Chen, Ying|Orlicky, David J|Matsumoto, Akiko|Singh, Surendra|Thompson, David C|Vasiliou, Vasilis
PMID: 21216231
Journal: Am J Pathol. 2011 Apr;178(4):1805-13.
Title: Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.
Author: Inoda, Satoko|Hirohashi, Yoshihiko|Torigoe, Toshihiko|Morita, Rena|Takahashi, Akari|Asanuma, Hiroko|Nakatsugawa, Munehide|Nishizawa, Satoshi|Tamura, Yasuaki|Tsuruma, Tetsuhiro|Terui, Takeshi|Kondo, Toru|Ishitani, Kunihiko|Hasegawa, Tadashi|Hirata, Koichi|
PMID: 21435460
Journal: Int J Colorectal Dis. 2011 Oct;26(10):1279-85.
Title: Isolation and characterization of spheroid cells from the HT29 colon cancer cell line.
Author: Fan, Xinlan|Ouyang, Nengyong|Teng, Hong|Yao, Herui
PMID: 21670985
Journal: Clin Cancer Res. 2011 Nov 1;17(21):6934-43.
Title: Common cancer stem cell gene variants predict colon cancer recurrence.
Author: Gerger, Armin|Zhang, Wu|Yang, Dongyun|Bohanes, Pierre|Ning, Yan|Winder, Thomas|LaBonte, Melissa J|Wilson, Peter M|Benhaim, Leonor|Paez, David|El-Khoueiry, Rita|El-Khoueiry, Anthony|Kahn, Michael|Lenz, Heinz-Josef
PMID: 21918173
Journal: Clin Transl Oncol. 2011 Dec;13(12):833-8.
Title: Colorectal cancer stem cell: a potential therapeutic target.
Author: Tao, H|Zhu, Y
PMID: 22126725
Journal: Cancers (Basel). 2011 Mar 22;3(1):1467-79.
Title: Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro.
Author: Olszewski, Ulrike|Liedauer, Richard|Ausch, Christoph|Thalhammer, Theresia|Hamilton, Gerhard
PMID: 24212669
Journal: Alcohol. 2012 Feb;46(1):37-49.
Title: Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer.
Author: Chiang, Chien-Ping|Jao, Shu-Wen|Lee, Shiao-Pieng|Chen, Pei-Chi|Chung, Chia-Chi|Lee, Shou-Lun|Nieh, Shin|Yin, Shih-Jiun
PMID: 21940137
Journal: Exp Mol Pathol. 2012 Feb;92(1):111-7.
Title: The expression pattern of aldehyde dehydrogenase 1 (ALDH1) is an independent prognostic marker for low survival in colorectal tumors.
Author: Vogler, Tobias|Kriegl, Lydia|Horst, David|Engel, Jutta|Sagebiel, Sabine|Schaffauer, Achim J|Kirchner, Thomas|Jung, Andreas
PMID: 22101256
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G655-63.
Title: EGFR regulation of colon cancer stem-like cells during aging and in response to the colonic carcinogen dimethylhydrazine.
Author: Nautiyal, Jyoti|Du, Jianhua|Yu, Yingjie|Kanwar, Shailender S|Levi, Edi|Majumdar, Adhip P N
PMID: 22281474
Journal: Am J Surg. 2012 May;203(5):649-653.
Title: Loss of expression of the cancer stem cell marker aldehyde dehydrogenase 1 correlates with advanced-stage colorectal cancer.
Author: Hessman, Crystal J|Bubbers, Emily J|Billingsley, Kevin G|Herzig, Daniel O|Wong, Melissa H
PMID: 22405917
Journal: J Cancer. 2012;3:231-40.
Title: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers.
Author: Langan, Russell C|Mullinax, John E|Ray, Satyajit|Raiji, Manish T|Schaub, Nicholas|Xin, Hong-Wu|Koizumi, Tomotake|Steinberg, Seth M|Anderson, Andrew|Wiegand, Gordon|Butcher, Donna|Anver, Miriam|Bilchik, Anton J|Stojadinovic, Alexander|Rudloff, Udo|Avital,
PMID: 22670157
Journal: Ann Surg Oncol. 2012 Dec;19(13):4193-201.
Title: Expression analysis of aldehyde dehydrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy.
Author: Kahlert, Christoph|Gaitzsch, Eva|Steinert, Gunnar|Mogler, Carolin|Herpel, Esther|Hoffmeister, Michael|Jansen, Lina|Benner, Axel|Brenner, Hermann|Chang-Claude, Jenny|Rahbari, Nuh|Schmidt, Thomas|Klupp, Fee|Grabe, Niels|Lahrmann, Bernd|Koch, Moritz|Halama,
PMID: 22878609
Journal: Mol Nutr Food Res. 2013 Apr;57(4):686-97.
Title: Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice.
Author: Leclerc, Daniel|Cao, Yuanhang|Deng, Liyuan|Mikael, Leonie G|Wu, Qing|Rozen, Rima
PMID: 23001810
Journal: Mod Pathol. 2013 Aug;26(8):1123-31.
Title: Colorectal micropapillary carcinomas are associated with poor prognosis and enriched in markers of stem cells.
Author: Lee, Hee Jin|Eom, Dae-Woon|Kang, Gil Hyun|Han, Sang Hak|Cheon, Gab Jin|Oh, Ho-Suk|Han, Koon Hee|Ahn, Heui June|Jang, Hyuk-Jai|Han, Myoung Sik
PMID: 23060121
Journal: Stem Cells. 2013 Mar;31(3):423-32.
Title: Preventive cancer stem cell-based vaccination reduces liver metastasis development in a rat colon carcinoma syngeneic model.
Author: Duarte, Sonia|Momier, David|Baque, Patrick|Casanova, Vincent|Loubat, Agnes|Samson, Michel|Guigonis, Jean-Marie|Staccini, Pascal|Saint-Paul, Marie-Christine|De Lima, Maria Pedroso|Carle, Georges F|Pierrefite-Carle, Valerie
PMID: 23193035
Journal: Cancer Invest. 2013 Jan;31(1):17-23.
Title: MiR-125a/b regulates the activation of cancer stem cells in paclitaxel-resistant colon cancer.
Author: Chen, Jixiang|Chen, Yuxiang|Chen, Zihua
PMID: 23327190
Journal: Hum Pathol. 2013 Jun;44(6):966-74.
Title: ALDH1 expression indicates chemotherapy resistance and poor outcome in node-negative rectal cancer.
Author: Avoranta, S Tuulia|Korkeila, Eija A|Ristamaki, Raija H|Syrjanen, Kari J|Carpen, Olli M|Pyrhonen, Seppo O|Sundstrom, Jari T T
PMID: 23332924
Journal: Cancer Res. 2013 Apr 1;73(7):2368-78.
Title: ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines.
Author: Swindall, Amanda F|Londono-Joshi, Angelina I|Schultz, Matthew J|Fineberg, Naomi|Buchsbaum, Donald J|Bellis, Susan L
PMID: 23358684
Journal: PLoS One. 2013;8(2):e56082.
Title: Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells.
Author: Leng, Zhengwei|Tao, Kaixiong|Xia, Qinghua|Tan, Jun|Yue, Zhongyi|Chen, Jinhuang|Xi, Hailin|Li, Jie|Zheng, Hai
PMID: 23418515
Journal: Asian Pac J Trop Med. 2013 Jul;6(7):574-7.
Title: Expression of aldehyde dehydrogenase 1 in colon cancer.
Author: Hou, Yi|Liu, Yi-Yi|Zhao, Xiao-Kun
PMID: 23768832
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jun;33(6):889-93.
Title: [CD133(+) Colo205 colorectal cancer cells express high levels of ALDH1 in serum-free culture].
Author: Li, Lixuan|Zhang, Shanshan|Liang, Fenfen|Lin, Yinghao|Li, Runhua|Chen, Chudi|Xiao, Bing
PMID: 23803205
Journal: J Proteomics. 2013 Oct 8;91:84-96.
Title: The secretome of colon cancer stem cells contains drug-metabolizing enzymes.
Author: Emmink, Benjamin L|Verheem, Andre|Van Houdt, Winan J|Steller, Ernst J A|Govaert, Klaas M|Pham, Thang V|Piersma, Sander R|Borel Rinkes, Inne H M|Jimenez, Connie R|Kranenburg, Onno
PMID: 23835434
Journal: Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author: Zhou, Jin|Li, Pu|Xue, Xiaofeng|He, Songbing|Kuang, Yuting|Zhao, Hong|Chen, Shaoji|Zhi, Qiaoming|Guo, Xiaobo
PMID: 23916687
Journal: Cancer Prev Res (Phila). 2013 Nov;6(11):1162-70.
Title: Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia.
Author: Bartley, Angela N|Parikh, Nila|Hsu, Chiu-Hsieh|Roe, Denise J|Buckmeier, Julie A|Corley, Lynda|Phipps, Ron A|Gallick, Gary|Lance, Peter|Thompson, Patricia A|Hamilton, Stanley R
PMID: 24008128
Journal: Carcinogenesis. 2014 Apr;35(4):795-806.
Title: Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.
Author: Neradugomma, Naveen K|Subramaniam, Dharmalingam|Tawfik, Ossama W|Goffin, Vincent|Kumar, T Rajendra|Jensen, Roy A|Anant, Shrikant
PMID: 24265293
Journal: Br J Cancer. 2014 Jan 21;110(2):430-4.
Title: ALDH1 is an independent prognostic factor for patients with stages II-III rectal cancer after receiving radiochemotherapy.
Author: Deng, Y|Zhou, J|Fang, L|Cai, Y|Ke, J|Xie, X|Huang, Y|Huang, M|Wang, J
PMID: 24327017
Journal: Oncol Lett. 2014 Feb;7(2):507-512.
Title: Expression and prognostic value of tumor stem cell markers ALDH1 and CD133 in colorectal carcinoma.
Author: Zhou, Fei|Mu, Yin-Dong|Liang, Jun|Liu, Zhi-Xin|Chen, Hong-Sheng|Zhang, Ji-Fei
PMID: 24396478
Journal: Oncol Rep. 2014 Mar;31(3):1380-8.
Title: TWIST1 and SNAI1 as markers of poor prognosis in human colorectal cancer are associated with the expression of ALDH1 and TGF-beta1.
Author: Kim, Yong Hun|Kim, Gwangil|Kwon, Chang-Il|Kim, Jong Woo|Park, Pil Won|Hahm, Ki-Baik
PMID: 24402192
Journal: Pathol Oncol Res. 2014 Jul;20(3):707-17.
Title: Altered expression of multiple genes involved in retinoic acid biosynthesis in human colorectal cancer.
Author: Kropotova, Ekaterina S|Zinovieva, Olga L|Zyryanova, Alisa F|Dybovaya, Vera I|Prasolov, Vladimir S|Beresten, Sergey F|Oparina, Nina Yu|Mashkova, Tamara D
PMID: 24599561
Journal: BMC Cancer. 2014 Apr 4;14:241.
Title: P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer.
Author: Sim, Sung Hoon|Kang, Mi-Hyun|Kim, Yu Jung|Lee, Keun-Wook|Kim, Duck-Woo|Kang, Sung-Bum|Eom, Keun-Yong|Kim, Jae-Sung|Lee, Hye Seung|Kim, Jee Hyun
PMID: 24708484
Journal: Br J Cancer. 2014 Jun 10;110(12):2935-44.
Title: Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer.
Author: Goossens-Beumer, I J|Zeestraten, E C M|Benard, A|Christen, T|Reimers, M S|Keijzer, R|Sier, C F M|Liefers, G J|Morreau, H|Putter, H|Vahrmeijer, A L|van de Velde, C J H|Kuppen, P J K
PMID: 24786601
Journal: J Surg Res. 2014 Nov;192(1):82-9.
Title: The impact of Aldehyde dehydrogenase 1 expression on prognosis for metastatic colon cancer.
Author: Fitzgerald, Timothy L|Rangan, Swathi|Dobbs, Larry|Starr, Shane|Sigounas, George
PMID: 24953984
Journal: Int J Clin Exp Pathol. 2014 May 15;7(6):2976-86. eCollection 2014.
Title: Distinct patterns of ALDH1A1 expression predict metastasis and poor outcome of colorectal carcinoma.
Author: Xu, Sen-Lin|Zeng, Dong-Zu|Dong, Wei-Guo|Ding, Yan-Qing|Rao, Jun|Duan, Jiang-Jie|Liu, Qing|Yang, Jing|Zhan, Na|Liu, Ying|Hu, Qi-Ping|Zhang, Xia|Cui, You-Hong|Kung, Hsiang-Fu|Yu, Shi-Cang|Bian, Xiu-Wu
PMID: 25031716
Journal: Proteome Sci. 2014 Jul 11;12:39.
Title: Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.
Author: Rajcevic, Uros|Knol, Jaco C|Piersma, Sander|Bougnaud, Sebastien|Fack, Fred|Sundlisaeter, Eirik|Sondenaa, Karl|Myklebust, Reidar|Pham, Thang V|Niclou, Simone P|Jimenez, Connie R
PMID: 25075203
Journal: PLoS One. 2014 Sep 19;9(9):e107514.
Title: Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.
Author: Buhrmann, Constanze|Kraehe, Patricia|Lueders, Cora|Shayan, Parviz|Goel, Ajay|Shakibaei, Mehdi
PMID: 25238234
Journal: Biomed Pharmacother. 2014 Oct;68(8):911-6.
Title: Colon cancer: cancer stem cells markers, drug resistance and treatment.
Author: Kozovska, Zuzana|Gabrisova, Veronika|Kucerova, Lucia
PMID: 25458789
Journal: J Surg Oncol. 2015 Feb;111(2):243-7.
Title: ALDH1 is a prognostic factor for patients treated with neoadjuvant chemoradiotherapy and radical resection for stage III rectal cancer.
Author: Oh, Seung Yeop|Sohn, Se Hwa|Yim, Hyunee|Lee, Dakeun|Suh, Kwang Wook|Kim, Young Bae
PMID: 25270363
Journal: Adv Exp Med Biol. 2015;815:281-94.
Title: Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.
Author: Singh, S|Arcaroli, J|Thompson, D C|Messersmith, W|Vasiliou, V
PMID: 25427913
Journal: Mol Med Rep. 2015 May;11(5):3894-9.
Title: Aldehyde dehydrogenase 1: a specific cancer stem cell marker for human colorectal carcinoma.
Author: Zhou, Fei|Mu, Yin-Dong|Liang, Jun|Liu, Zhi-Xin|Zhou, Dan|Ning, Wen-Long|Li, Yue-Zhen|Ding, Dong|Zhang, Ji-Fei
PMID: 25585687
Journal: Oncotarget. 2015 Mar 20;6(8):5903-17.
Title: Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.
Author: Aguilera, Oscar|Gonzalez-Sancho, Jose Manuel|Zazo, Sandra|Rincon, Raul|Fernandez, Agustin F|Tapia, Olga|Canals, Francesc|Morte, Beatriz|Calvanese, Vincenzo|Orgaz, Jose L|Niell, Nuria|Aguilar, Susana|Freije, Jose M|Grana, Osvaldo|Pisano, David G|Borrero, A
PMID: 25788273
Journal: PLoS One. 2015 Jun 22;10(6):e0131108.
Title: A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer.
Author: Arvai, Kevin J|Hsu, Ya-Hsuan|Lee, Lobin A|Jones, Dan
PMID: 26098881
Journal: Cancer Lett. 2015 Oct 10;367(1):34-42.
Title: Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors.
Author: Lee, Sun-Hwa|Hong, Jun Hwa|Park, Hwan Ki|Park, Jun Seok|Kim, Bo-Kyung|Lee, Jung-Yi|Jeong, Ji Yun|Yoon, Ghil Suk|Inoue, Masahiro|Choi, Gyu-Seog|Lee, In-Kyu
PMID: 26185002
Journal: PLoS One. 2015 Jul 17;10(7):e0132977.
Title: Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.
Author: Alberti, Loredana|Losi, Lorena|Leyvraz, Serge|Benhattar, Jean
PMID: 26185996
Journal: Biomark Med. 2015;9(8):777-90.
Title: Clinicopathological significance of ALDH1A1 in lung, colorectal, and breast cancers: a meta-analysis.
Author: Zhou, Yang|Wang, Yixun|Ju, Xinxin|Lan, Jiaojiao|Zou, Hong|Li, Shugang|Qi, Yan|Jia, Wei|Hu, Jianming|Liang, Weihua|Zhang, Wenjie|Pang, Lijuan|Li, Feng
PMID: 26230297
Journal: Nanomedicine. 2015 Nov;11(8):1883-92.
Title: Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells.
Author: Gener, Petra|Gouveia, Luis Pleno|Sabat, Guillem Romero|de Sousa Rafael, Diana Fernandes|Fort, Nuria Bergada|Arranja, Alexandra|Fernandez, Yolanda|Prieto, Rafael Minana|Ortega, Joan Sayos|Arango, Diego|Abasolo, Ibane|Videira, Mafalda|Schwartz, Simo Jr
PMID: 26238079
Journal: Iran J Cancer Prev. 2015 Oct;8(5):e3446.
Title: Verification of ALDH Activity as a Biomarker in Colon Cancer Stem Cells-Derived HT-29 Cell Line.
Author: Khorrami, Samaneh|Zavaran Hosseini, Ahmad|Mowla, Seyed Javad|Malekzadeh, Reza
PMID: 26634106
Journal: PLoS One. 2015 Dec 18;10(12):e0145164.
Title: Prognostic Value of Cancer Stem Cell Marker ALDH1 Expression in Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author: Chen, Jinhuang|Xia, Qinghua|Jiang, Bin|Chang, Weilong|Yuan, Wenzheng|Ma, Zhijun|Liu, Zhengyi|Shu, Xiaogang
PMID: 26682730
Journal: Arkh Patol. 2015 Sep-Oct;77(5):26-30.
Title: [Prognostic values of the clinical, morphological and molecular biological characteristics of colon adenocarcinoma].
Author: Raskin, G A|Pozharissky, K M|Orlova, R V|Petrov, S V
PMID: 26978017
Journal: Pathol Oncol Res. 2016 Jan;22(1):121-7.
Title: Aldehyde Dehydragenase 1 and Nodal as Significant Prognostic Markers in Colorectal Cancer.
Author: Li, Hui|Jiang, Yang|Pei, Fenghua|Li, Lu|Yan, Bingzhu|Geng, Xinyu|Liu, Bingrong
PMID: 26358078
Journal: Tumour Biol. 2016 Jan;37(1):7-21.
Title: Cancer stem cells in human digestive tract malignancies.
Author: Rassouli, Fatemeh B|Matin, Maryam M|Saeinasab, Morvarid
PMID: 26446457
Journal: Tumour Biol. 2016 Mar;37(3):3571-80.
Title: Clinical influence of cancer stem cells on residual disease after preoperative chemoradiotherapy for rectal cancer.
Author: Yoon, Ghilsuk|Kim, Sol-Min|Kim, Hye Jin|Seo, An Na
PMID: 26456957
Journal: Carcinogenesis. 2016 Apr;37(4):385-96.
Title: An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis.
Author: Ahmed, Ishfaq|Roy, Badal C|Subramaniam, Dharmalingam|Ganie, Showkat Ahmad|Kwatra, Deep|Dixon, Dan|Anant, Shrikant|Zargar, Mohammad Afzal|Umar, Shahid
PMID: 26785732
Journal: PLoS One. 2016 May 6;11(5):e0155160.
Title: Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer.
Author: Kim, Jin Cheon|Ha, Ye Jin|Tak, Ka Hee|Roh, Seon Ae|Kim, Chan Wook|Kim, Tae Won|Kim, Seon-Kyu|Kim, Seon-Young|Cho, Dong-Hyung|Kim, Yong Sung
PMID: 27152521
Journal: Thromb Res. 2016 Apr;140 Suppl 1:S195-6.
Title: PO-52 - Effect of tissue factor expression by colorectal cancer on cancer stem cell activity.
Author: Clouston, H W|Lamb, R|Duff, S|Kirwan, C C
PMID: 27161739
Journal: J Microbiol Biotechnol. 2016 Aug 28;26(8):1490-503.
Title: Combination Therapy of Lactobacillus plantarum Supernatant and 5-Fluouracil Increases Chemosensitivity in Colorectal Cancer Cells.
Author: An, JaeJin|Ha, Eun-Mi
PMID: 27221111
Journal: Carcinogenesis. 2016 Aug;37(8):777-786.
Title: Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway.
Author: Misiorek, Julia O|Lahdeniemi, Iris A K|Nystrom, Joel H|Paramonov, Valeriy M|Gullmets, Josef A|Saarento, Helena|Rivero-Muller, Adolfo|Husoy, Trine|Taimen, Pekka|Toivola, Diana M
PMID: 27234655
Journal: Pathol Res Pract. 2016 Sep;212(9):791-9.
Title: Nuclear aldehyde dehydrogenase 1A1 (ALDH1A1) expression is a favorable prognostic indicator in colorectal carcinoma.
Author: Wang, Lili|Lin, Dongliang|Fu, Ying|Lai, Maode
PMID: 27461829
Journal: BMC Cancer. 2016 Nov 10;16(1):876.
Title: Metastasis-associated in colon cancer-1 and aldehyde dehydrogenase 1 are metastatic and prognostic biomarker for non-small cell lung cancer.
Author: Zhou, Lei|Yu, Lan|Zhu, Bo|Wu, Shiwu|Song, Wenqing|Gong, Xiaomeng|Wang, Danna
PMID: 27832750
Journal: BMC Cancer. 2016 Nov 18;16(1):902.
Title: Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
Author: Orue, Andrea|Chavez, Valery|Strasberg-Rieber, Mary|Rieber, Manuel
PMID: 27863474
Journal: Oncol Lett. 2016 Nov;12(5):3250-3258.
Title: Microarray analysis of differentially-expressed genes and linker genes associated with the molecular mechanism of colorectal cancer.
Author: Shen, Xingjie|Yue, Meng|Meng, Fansheng|Zhu, Jingyu|Zhu, Xiaoyan|Jiang, Yakun
PMID: 27899990
Journal: J Proteomics Bioinform. 2016 Oct;9(10):238-247.
Title: Protein Markers Associated with an ALDH Sub-Population in Colorectal Cancer.
Author: Yang, Rui|Liu, Xinhua|Thakolwiboon, Smathorn|Zhu, Jianhui|Pei, Xiucong|An, Mingrui|Tan, Zhijing|Lubman, David M
PMID: 28503055
Journal: Curr Stem Cell Res Ther. 2017;12(1):19-30.
Title: Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer.
Author: Fedyanin, Mikhail|Anna, Popova|Elizaveta, Polyanskaya|Sergei, Tjulandin
PMID: 27593447
Journal: Mod Pathol. 2017 Feb;30(2):278-285.
Title: Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas.
Author: Inaguma, Shingo|Lasota, Jerzy|Wang, Zengfeng|Felisiak-Golabek, Anna|Ikeda, Hiroshi|Miettinen, Markku
PMID: 27813511
Journal: Clin Colorectal Cancer. 2017 Jun;16(2):93-102.
Title: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer.
Author: Wahab, S M Riajul|Islam, Farhadul|Gopalan, Vinod|Lam, Alfred King-Yin
PMID: 28237538
Journal: J Clin Diagn Res. 2017 Jan;11(1):EC17-EC23.
Title: Evaluation of the Role of ALDH1 as Cancer Stem Cell Marker in Colorectal Carcinoma: An Immunohistochemical Study.
Author: Holah, Nanis Shawky|Aiad, Hayam Abd-El-Samie|Asaad, Nancy Yousif|Elkhouly, Enas Abobakr|Lasheen, Ayat Gamal
PMID: 28273973
Journal: Nutrients. 2017 Apr 10;9(4). pii: nu9040368.
Title: Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.
Author: Pereira, Lucilia P|Silva, Patricia|Duarte, Marlene|Rodrigues, Liliana|Duarte, Catarina M M|Albuquerque, Cristina|Serra, Ana Teresa
PMID: 28394276
Journal: BMC Surg. 2017 Apr 21;17(1):47.
Title: Evaluation of the correlation of vasculogenic mimicry, ALDH1, KAI1 and microvessel density in the prediction of metastasis and prognosis in colorectal carcinoma.
Author: Zhu, Bo|Zhou, Lei|Yu, Lan|Wu, Shiwu|Song, Wenqing|Gong, Xiaomeng|Wang, Danna
PMID: 28431527
Journal: Oncotarget. 2017 Jul 11;8(28):45311-45322.
Title: Temporal and spatial changes of cells positive for stem-like markers in different compartments and stages of human colorectal adenoma-carcinoma sequence.
Author: Cui, Guanglin|Xu, Gang|Zhu, Li|Pang, Zhigang|Zheng, Wei|Li, Zhenfeng|Yuan, Aping
PMID: 28484082
Journal: J Surg Oncol. 2017 Nov;116(6):706-715.
Title: Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.
Author: Handa, Tadashi|Katayama, Ayaka|Yokobori, Takehiko|Yamane, Arito|Horiguchi, Jun|Kawabata-Iwakawa, Reika|Rokudai, Susumu|Bao, Pinjie|Gombodorj, Navchaa|Altan, Bolag|Kaira, Kyoichi|Asao, Takayuki|Kuwano, Hiroyuki|Nishiyama, Masahiko|Oyama, Tetsunari
PMID: 28570747
Journal: Phytother Res. 2017 Sep;31(9):1369-1375.
Title: Synergy between Auraptene, Ionizing Radiation, and Anticancer Drugs in Colon Adenocarcinoma Cells.
Author: Moussavi, Mahdi|Haddad, Farhang|Rassouli, Fatemeh B|Iranshahi, Mehrdad|Soleymanifard, Shokouhozaman
PMID: 28675489
Journal: Br J Cancer. 2017 Nov 7;117(10):1537-1543.
Title: Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.
Author: Matsumoto, Akiko|Arcaroli, John|Chen, Ying|Gasparetto, Maura|Neumeister, Veronique|Thompson, David C|Singh, Surendra|Smith, Clayton|Messersmith, Wells|Vasiliou, Vasilis
PMID: 28881356
Journal: Autophagy. 2017;13(12):2056-2071.
Title: ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.
Author: Piao, Shengfu|Ojha, Rani|Rebecca, Vito W|Samanta, Arabinda|Ma, Xiao-Hong|Mcafee, Quentin|Nicastri, Michael C|Buckley, Meghan|Brown, Eric|Winkler, Jeffrey D|Gimotty, Phyllis A|Amaravadi, Ravi K
PMID: 28981387
Journal: Pathology. 2017 Dec;49(7):721-730.
Title: The prognostic value of cancer stem-like cell markers SOX2 and CD133 in stage III colon cancer is modified by expression of the immune-related markers FoxP3, PD-L1 and CD3.
Author: Miller, T J|McCoy, M J|Hemmings, C|Bulsara, M K|Iacopetta, B|Platell, C F
PMID: 29102042
Journal: Cell Physiol Biochem. 2017;44(3):1051-1063.
Title: Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer.
Author: Wang, Hefei|Liu, Bing|Wang, Jing|Li, Jinglin|Gong, Ying|Li, Sisi|Wang, Chunli|Cui, Bai|Xue, Xiaoyuan|Yang, Mengying|Fan, Wenjun|Kang, Zhijie|Kamran, Muhammad|Xu, Jie|Tian, Pengfei|Luo, Yuanyuan|Hou, Zhijie|Dong, Lin|Ren, Yanling|Li, Man|Wen, Qingping|Chen
PMID: 29179207
Journal: J Surg Res. 2017 Dec;220:353-362.
Title: CEACAM1 is associated with recurrence after hepatectomy for colorectal liver metastasis.
Author: Yamaguchi, Shunsuke|Yokoyama, Shozo|Ueno, Masaki|Hayami, Shinya|Mitani, Yasuyuki|Takeuchi, Akihiro|Shively, John E|Yamaue, Hiroki
PMID: 29180203
Journal: J Cell Physiol. 2018 Feb;233(2):727-735.
Title: Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.
Author: Bhatlekar, Seema|Viswanathan, Vignesh|Fields, Jeremy Z|Boman, Bruce M
PMID: 28464221
Journal: Int J Oncol. 2018 Mar;52(3):721-732.
Title: CD133 expression predicts post-operative recurrence in patients with colon cancer with peritoneal metastasis.
Author: Nagata, Hiroshi|Ishihara, Soichiro|Kishikawa, Junko|Sonoda, Hirofumi|Murono, Koji|Emoto, Shigenobu|Kaneko, Manabu|Sasaki, Kazuhito|Otani, Kensuke|Nishikawa, Takeshi|Tanaka, Toshiaki|Kiyomatsu, Tomomichi|Hata, Keisuke|Kawai, Kazushige|Nozawa, Hiroaki
PMID: 29328371
Journal: Oncogene. 2018 Mar;37(12):1669-1684.
Title: Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
Author: Solomon, Hilla|Dinowitz, Nathan|Pateras, Ioannis S|Cooks, Tomer|Shetzer, Yoav|Molchadsky, Alina|Charni, Meital|Rabani, Stav|Koifman, Gabriela|Tarcic, Ohad|Porat, Ziv|Kogan-Sakin, Ira|Goldfinger, Naomi|Oren, Moshe|Harris, Curtis C|Gorgoulis, Vassilis G|Rot
PMID: 29343849
Journal: Oncotarget. 2018 Feb 5;9(17):13551-13564.
Title: Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways.
Author: Vishnubalaji, Radhakrishnan|Manikandan, Muthurangan|Fahad, Mohamed|Hamam, Rimi|Alfayez, Musaad|Kassem, Moustapha|Aldahmash, Abdullah|Alajez, Nehad M
PMID: 29568377
Journal: Cell Physiol Biochem. 2018;46(2):860-872.
Title: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
Author: Leng, Zhengwei|Xia, Qinghua|Chen, Jinhuang|Li, Yong|Xu, Jiqian|Zhao, Ende|Zheng, Hai|Ai, Walden|Dong, Jiangchuan
PMID: 29627827
Journal: Oncol Rep. 2018 Jun;39(6):2881-2891.
Title: Assessing stemness and proliferation properties of the newly established colon cancer 'stem' cell line, CSC480 and novel approaches to identify dormant cancer cells.
Author: Alowaidi, Faisal|Hashimi, Saeed Mujahid|Alqurashi, Naif|Alhulais, Reem|Ivanovski, Saso|Bellette, Bernadette|Meedenyia, Adrian|Lam, Alfred|Wood, Stephen
PMID: 29693155
Journal: Cancer Res. 2018 Jul 15;78(14):3793-3808.
Title: The miR-371 approximately 373 Cluster Represses Colon Cancer Initiation and Metastatic Colonization by Inhibiting the TGFBR2/ID1 Signaling Axis.
Author: Ullmann, Pit|Rodriguez, Fabien|Schmitz, Martine|Meurer, Steffen K|Qureshi-Baig, Komal|Felten, Paul|Ginolhac, Aurelien|Antunes, Laurent|Frasquilho, Sonia|Zugel, Nikolaus|Weiskirchen, Ralf|Haan, Serge|Letellier, Elisabeth
PMID: 29748374
Journal: Med Sci Monit. 2018 May 7;24:2864-2872.
Title: Expression of Aldehyde Dehydrogenase 1A1 (ALDH1A1) as a Prognostic Biomarker in Colorectal Cancer Using Immunohistochemistry.
Author: Yang, Wangshuo|Wang, Yang|Wang, Wei|Chen, Zhuming|Bai, Guang
PMID: 29748529
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Cancer Sci. 2018 Aug;109(8):2479-2489.
Title: DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene.
Author: Tanaka, Kiyoko|Ikeda, Narumi|Miyashita, Kazuya|Nuriya, Hideko|Hara, Takahiko
PMID: 29869821
Journal: BMC Cancer. 2018 Jun 15;18(1):656.
Title: ALDH1A inhibition sensitizes colon cancer cells to chemotherapy.
Author: Kozovska, Z|Patsalias, A|Bajzik, V|Durinikova, E|Demkova, L|Jargasova, S|Smolkova, B|Plava, J|Kucerova, L|Matuskova, M
PMID: 29902974
Journal: Clin Colorectal Cancer. 2018 Sep;17(3):e579-e592.
Title: Cancer Stemness, Immune Cells, and Epithelial-Mesenchymal Transition Cooperatively Predict Prognosis in Colorectal Carcinoma.
Author: Xu, Fangying|Li, Si|Zhang, Jing|Wang, Lili|Wu, Xuesong|Wang, Jing|Huang, Qiong|Lai, Maode
PMID: 29921496
Journal: Nutrients. 2018 Jul 12;10(7). pii: nu10070888.
Title: Resveratrol Chemosensitizes TNF-beta-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.
Author: Buhrmann, Constanze|Yazdi, Mina|Popper, Bastian|Shayan, Parviz|Goel, Ajay|Aggarwal, Bharat B|Shakibaei, Mehdi
PMID: 30002278
Journal: J Pineal Res. 2018 Aug 9:e12519.
Title: Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis.
Author: Lee, Jun Hee|Yun, Chul Won|Han, Yong-Seok|Kim, SangMin|Jeong, Dongjun|Kwon, Hyog Young|Kim, Hyeongjoo|Baek, Moo-Jun|Lee, Sang Hun
PMID: 30091203
Journal: Cancer Lett. 2018 Nov 1;436:119-128.
Title: Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway.
Author: Tan, Xiao|Zhang, Zhongqiang|Yao, Hongliang|Shen, Liangfang
PMID: 30118845
Journal: Oncol Lett. 2018 Sep;16(3):4008-4012.
Title: Effect of As2O3 on colorectal CSCs stained with ALDH1 in primary cell culture in vitro.
Author: Ning, Ke|Ning, Wenlong|Ning, Xiaoting|Wang, Xueyan|Zhou, Fei
PMID: 30128021
Journal: J Gastrointest Cancer. 2018 Aug 23. pii: 10.1007/s12029-018-0156-6.
Title: The Prognostic Value of Cancer Stem Cell Markers (Notch1, ALDH1, and CD44) in Primary Colorectal Carcinoma.
Author: Mohamed, Salem Y|Kaf, Randa Mohamed|Ahmed, Mona Mostafa|Elwan, Amira|Ashour, Hassan R|Ibrahim, Amr
PMID: 30136202
Journal: Cancer Lett. 2018 Nov 28;437:13-24.
Title: Montelukast, a CysLT1 receptor antagonist, reduces colon cancer stemness and tumor burden in a mouse xenograft model of human colon cancer.
Author: Bellamkonda, Kishan|Satapathy, Shakti Ranjan|Douglas, Desiree|Chandrashekar, Naveenkumar|Selvanesan, Benson Chellakkan|Liu, Minghui|Savari, Sayeh|Jonsson, Gunilla|Sjolander, Anita
PMID: 30144515
Journal: Cell Death Dis. 2018 Aug 30;9(9):896.
Title: High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling.
Author: Kim, Donghyeok|Choi, Bo-Hyun|Ryoo, In-Geun|Kwak, Mi-Kyoung
PMID: 30166520
Journal: Onco Targets Ther. 2018 Aug 21;11:5047-5057.
Title: Analysis of the clinical significance of DCLK1(+) colorectal cancer using novel monoclonal antibodies against DCLK1.
Author: Dai, Tianqi|Hu, Yunlong|Lv, Fulian|Ozawa, Tatsuhiko|Sun, Xin|Huang, Jingjing|Han, Xiaojian|Kishi, Hiroyuki|Muraguchi, Atsushi|Jin, Aishun
PMID: 30174443
Journal: Cancers (Basel). 2018 Sep 25;10(10). pii: cancers10100353.
Title: Destruxin B Suppresses Drug-Resistant Colon Tumorigenesis and Stemness Is Associated with the Upregulation of miR-214 and Downregulation of mTOR/beta-Catenin Pathway.
Author: Wu, Szu-Yuan|Huang, Yan-Jiun|Tzeng, Yew-Min|Huang, Chi-Ying F|Hsiao, Michael|Wu, Alexander T H|Huang, Tse-Hung
PMID: 30257507
Journal: Int J Oncol. 2018 Sep 18.
Title: Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression.
Author: Turano, Mimmo|Costabile, Valeria|Cerasuolo, Andrea|Duraturo, Francesca|Liccardo, Raffaella|Delrio, Paolo|Pace, Ugo|Rega, Daniela|Dodaro, Concetta Anna|Milone, Marco|Izzo, Paola|De Rosa, Marina
PMID: 30272331
Journal: Cell Tissue Res. 2018 Oct 3. pii: 10.1007/s00441-018-2933-8.
Title: Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture.
Author: Hirashima, Kanji|Yue, Fengming|Kobayashi, Mikiko|Uchida, Yuriko|Nakamura, Shunsuke|Tomotsune, Daihachiro|Matsumoto, Ken|Takizawa-Shirasawa, Sakiko|Yokoyama, Tadayuki|Kanno, Hiroyuki|Sasaki, Katsunori
PMID: 30284085
Journal: PLoS One. 2018 Oct 11;13(10):e0205536.
Title: ALDH1A1 expression is associated with poor differentiation, 'right-sidedness' and poor survival in human colorectal cancer.
Author: van der Waals, Lizet M|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 30308036