Primary Site >> Stomach Cancer

Gene >> AKT1

Journal: Cancer Chemother Pharmacol. 2000;46 Suppl:S37-42.
Title: SEREX analysis of gastric cancer antigens.
Author: Obata, Y|Takahashi, T|Sakamoto, J|Tamaki, H|Tominaga, S|Hamajima, N|Chen, Y T|Old, L J
PMID: 10950146
Journal: Cancer Res. 2000 Nov 1;60(21):6201-7.
Title: Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy.
Author: Izuishi, K|Kato, K|Ogura, T|Kinoshita, T|Esumi, H
PMID: 11085546
Journal: Lab Invest. 2002 Mar;82(3):285-91.
Title: Promoter methylation and silencing of PTEN in gastric carcinoma.
Author: Kang, Young-Hwa|Lee, Hye Seung|Kim, Woo Ho
PMID: 11896207
Journal: J Biol Chem. 2002 Sep 13;277(37):34359-66.
Title: Induction of apoptosis by stomach cancer-associated protein-tyrosine phosphatase-1.
Author: Takada, Toshiyuki|Noguchi, Tetsuya|Inagaki, Kenjiro|Hosooka, Tetsuya|Fukunaga, Kaoru|Yamao, Takuji|Ogawa, Wataru|Matozaki, Takashi|Kasuga, Masato
PMID: 12101188
Journal: Oncogene. 2002 Jul 25;21(32):4885-93.
Title: K252a inhibits the oncogenic properties of Met, the HGF receptor.
Author: Morotti, Alessandro|Mila, Silvia|Accornero, Paolo|Tagliabue, Emma|Ponzetto, Carola
PMID: 12118367
Journal: Br J Cancer. 2003 Mar 10;88(5):796-802.
Title: Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells.
Author: Akagi, M|Kawaguchi, M|Liu, W|McCarty, M F|Takeda, A|Fan, F|Stoeltzing, O|Parikh, A A|Jung, Y D|Bucana, C D|Mansfield, P F|Hicklin, D J|Ellis, L M
PMID: 12618892
Journal: Oncol Rep. 2003 Sep-Oct;10(5):1467-71.
Title: P38 MAPK pathway is involved in the urokinase plasminogen activator expression in human gastric SNU-638 cells.
Author: Shin, Boo A|Yoo, Hyeon G|Kim, Hong S|Kim, Mi H|Hwang, Young S|Chay, Kee O|Lee, Kee Y|Ahn, Bong W|Jung, Young D
PMID: 12883725
Journal: World J Gastroenterol. 2003 Oct;9(10):2362-5.
Title: Antiproliferative effect of octreotide on gastric cancer cells mediated by inhibition of Akt/PKB and telomerase.
Author: Gao, Shan|Yu, Bao-Ping|Li, Yan|Dong, Wei-Guo|Luo, He-Sheng
PMID: 14562414
Journal: Cancer Res. 2003 Nov 1;63(21):7345-55.
Title: A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Author: Christensen, James G|Schreck, Randall|Burrows, Jon|Kuruganti, Poonam|Chan, Emily|Le, Phuong|Chen, Jeffrey|Wang, Xueyan|Ruslim, Lany|Blake, Robert|Lipson, Kenneth E|Ramphal, John|Do, Steven|Cui, Jingrong J|Cherrington, Julie M|Mendel, Dirk B
PMID: 14612533
Journal: Cancer Sci. 2003 Dec;94(12):1066-73.
Title: Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers.
Author: Nam, Seon Young|Jung, Gyung-Ah|Hur, Gwong-Cheung|Chung, Hee-Yong|Kim, Woo Ho|Seol, Dai-Wu|Lee, Byung Lan
PMID: 14662022
Journal: APMIS. 2003 Dec;111(12):1105-13.
Title: Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis.
Author: Nam, Seon Young|Lee, Hye Seung|Jung, Gyung-Ah|Choi, Jimi|Cho, Sung Jin|Kim, Min Kyu|Kim, Woo Ho|Lee, Byung Lan
PMID: 14678019
Journal: J Cancer Res Clin Oncol. 2004 Jan;130(1):8-14. Epub 2003 Nov 7.
Title: Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.
Author: Osaki, Mitsuhiko|Kase, Satoru|Adachi, Keiko|Takeda, Ami|Hashimoto, Kiyoshi|Ito, Hisao
PMID: 14605879
Journal: J Virol. 2004 Feb;78(4):1697-705.
Title: Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway.
Author: Fukuda, Makoto|Longnecker, Richard
PMID: 14747535
Journal: Int J Oncol. 2004 May;24(5):1229-34.
Title: Smad2 mediates Erk1/2 activation by TGF-beta1 in suspended, but not in adherent, gastric carcinoma cells.
Author: Lee, Mi-Sook|Ko, Seong-Gyu|Kim, Hwang-Phill|Kim, Yong-Bae|Lee, Sung-Yul|Kim, Sang-Gyun|Jong, Hyun-Soon|Kim, Tae-You|Lee, Jung Weon|Bang, Yung-Jue
PMID: 15067346
Journal: Oncogene. 2004 Jun 17;23(28):4921-9.
Title: STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.
Author: Kanda, Naoki|Seno, Hiroshi|Konda, Yoshitaka|Marusawa, Hiroyuki|Kanai, Masashi|Nakajima, Toshio|Kawashima, Tomoko|Nanakin, Apichart|Sawabu, Tateo|Uenoyama, Yoshito|Sekikawa, Akira|Kawada, Mayumi|Suzuki, Katsumasa|Kayahara, Takahisa|Fukui, Hirokazu|Sawada,
PMID: 15077160
Journal: Oncogene. 2004 Aug 26;23(39):6603-11.
Title: Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells.
Author: Hwang, Young S|Jeong, Min|Park, Jung S|Kim, Mi H|Lee, Dae B|Shin, Boo A|Mukaida, Naofumi|Ellis, Lee M|Kim, Hyeong R|Ahn, Bong W|Jung, Young D
PMID: 15208668
Journal: Dig Dis Sci. 2004 Jun;49(6):948-53.
Title: Cyclooxygenase-2 inhibitor nimesulide suppresses telomerase activity by blocking Akt/PKB activation in gastric cancer cell line.
Author: Baoping, Yu|Guoyong, Hu|Jieping, Yu|Zongxue, Ran|Hesheng, Luo
PMID: 15309882
Journal: Surgery. 2004 Sep;136(3):686-92.
Title: Regulation of vascular endothelial growth factor expression in human gastric cancer cells by interleukin-1beta.
Author: Kawaguchi, Michiya|Akagi, Morihisa|Gray, Mike J|Liu, Wenbiao|Fan, Fan|Ellis, Lee M
PMID: 15349119
Journal: Cancer. 2004 Nov 15;101(10):2177-86.
Title: Preclinical evaluation of antisense bcl-2 as a chemosensitizer for patients with gastric carcinoma.
Author: Kim, Ryungsa|Emi, Manabu|Tanabe, Kazuaki|Toge, Tetsuya
PMID: 15476281
Journal: Cancer Res. 2004 Nov 1;64(21):7962-70.
Title: RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival.
Author: Shinomiya, Nariyoshi|Gao, Chong Feng|Xie, Qian|Gustafson, Margaret|Waters, David J|Zhang, Yu-Wen|Vande Woude, George F
PMID: 15520203
Journal: J Biol Chem. 2005 Feb 11;280(6):4279-88. Epub 2004 Nov 23.
Title: NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages.
Author: Basak, Chaitali|Pathak, Sushil Kumar|Bhattacharyya, Asima|Mandal, Debabrata|Pathak, Shresh|Kundu, Manikuntala
PMID: 15561713
Journal: J Virol. 2005 Feb;79(4):2375-82.
Title: Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signaling.
Author: Morrison, Jennifer A|Raab-Traub, Nancy
PMID: 15681438
Journal: Biochemistry. 2005 Mar 15;44(10):4074-82.
Title: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad.
Author: Antignani, Antonella|Youle, Richard J
PMID: 15751984
Journal: Gastroenterology. 2005 Mar;128(3):642-53.
Title: REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.
Author: Sekikawa, Akira|Fukui, Hirokazu|Fujii, Shigehiko|Takeda, Jun|Nanakin, Apichart|Hisatsune, Hiroshi|Seno, Hiroshi|Takasawa, Shin|Okamoto, Hiroshi|Fujimori, Takahiro|Chiba, Tsutomu
PMID: 15765400
Journal: DNA Cell Biol. 2005 Mar;24(3):141-7.
Title: COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines.
Author: Honjo, Soichiro|Osaki, Mitsuhiko|Ardyanto, Tonang Dwi|Hiramatsu, Toshiki|Maeta, Noritaka|Ito, Hisao
PMID: 15767780
Journal: Cancer Sci. 2005 Mar;96(3):170-5.
Title: Helicobacter pylori-dependent NF-kappa B activation in newly established Mongolian gerbil gastric cancer cell lines.
Author: Nozaki, Koji|Tanaka, Harunari|Ikehara, Yuzuru|Cao, Xueyuan|Nakanishi, Hayao|Azuma, Takeshi|Yamazaki, Shiho|Yamaoka, Yoshio|Shimizu, Nobuyuki|Mafune, Ken-ichi|Kaminishi, Michio|Tatematsu, Masae
PMID: 15771620
Journal: Cancer. 2005 May 1;103(9):1800-9.
Title: Chemosensitization by STI571 targeting the platelet-derived growth factor/platelet-derived growth factor receptor-signaling pathway in the tumor progression and angiogenesis of gastric carcinoma.
Author: Kim, Ryungsa|Emi, Manabu|Arihiro, Koji|Tanabe, Kazuaki|Uchida, Yoko|Toge, Tetsuya
PMID: 15786421
Journal: Biochem Biophys Res Commun. 2005 May 13;330(3):760-7.
Title: Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
Author: Yi, Ho-Keun|Kim, Sun-Young|Hwang, Pyoung-Han|Kim, Chan-Young|Yang, Doo-Hyun|Oh, Youngman|Lee, Dae-Yeol
PMID: 15809062
Journal: Int J Oncol. 2005 May;26(5):1321-7.
Title: Overexpression of the N-terminal end of the p55gamma regulatory subunit of phosphatidylinositol 3-kinase blocks cell cycle progression in gastric carcinoma cells.
Author: Hu, Junbo|Liu, Shuangyou|Wang, Jing|Luo, Xuelai|Gao, Xia|Xia, Xianmin|Feng, Yongdong|Tao, Deding|Wang, Gangduo|Li, Xiping|Zhao, Jinshun|Ding, Hong|Reed, Eddie|Li, Qingdi Q|Gong, Jianping
PMID: 15809724
Journal: Clin Cancer Res. 2005 Apr 1;11(7):2518-25.
Title: Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer.
Author: Lee, Byung Lan|Lee, Hye Seung|Jung, Jieun|Cho, Sung Jin|Chung, Hee-Yong|Kim, Woo Ho|Jin, Young-Woo|Kim, Chong Soon|Nam, Seon Young
PMID: 15814628
Journal: Gut. 2005 May;54(5):591-600.
Title: Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.
Author: Min, Y|Adachi, Y|Yamamoto, H|Imsumran, A|Arimura, Y|Endo, T|Hinoda, Y|Lee, C-T|Nadaf, S|Carbone, D P|Imai, K
PMID: 15831900
Journal: Int J Cancer. 2005 Nov 10;117(3):376-80.
Title: Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer.
Author: Oki, Eiji|Baba, Hideo|Tokunaga, Eriko|Nakamura, Toshihiko|Ueda, Naoyuki|Futatsugi, Motonori|Mashino, Kohjiro|Yamamoto, Manabu|Ikebe, Masahiko|Kakeji, Yoshihiro|Maehara, Yoshihiko
PMID: 15900596
Journal: Cancer Lett. 2005 Jul 8;225(1):53-9.
Title: Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention.
Author: Ang, Kok Long|Shi, Diong Lang|Keong, Wong Wai|Epstein, Richard J
PMID: 15922857
Journal: Clin Exp Metastasis. 2005;22(2):137-47.
Title: Establishment and characterization of three novel human gastric cancer cell lines with differentiated intestinal phenotype derived from liver metastasis.
Author: Nakanishi, Hayao|Yasui, Kenzo|Ikehara, Yuzuru|Yokoyama, Hiroyuki|Munesue, Seiichi|Kodera, Yasuhiro|Tatematsu, Masae
PMID: 16086234
Journal: Exp Mol Med. 2005 Oct 31;37(5):391-8.
Title: PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells.
Author: Hwang, Pyoung Han|Kim, Sun Young|Lee, Jung Chang|Kim, Sun Jun|Yi, Ho Keun|Lee, Dae Yeol
PMID: 16264263
Journal: Int J Oncol. 2005 Dec;27(6):1677-83.
Title: Epithelial-mesenchymal transition in gastric cancer (Review).
Author: Katoh, Masaru
PMID: 16273224
Journal: J Environ Pathol Toxicol Oncol. 2005;24(4):261-9.
Title: Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human gastric cancer (AGS) cells.
Author: Kim, Min-Jung|Kim, Do-Hee|Na, Hye-Kyung|Oh, Tae Young|Shin, Chang-Yell|Surh Ph D Professor, Young-Joon
PMID: 16393120
Journal: J Surg Res. 2006 Jan;130(1):80-7.
Title: Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.
Author: Yamashita, Hiroharu|Kitayama, Joji|Shida, Dai|Yamaguchi, Hironori|Mori, Ken|Osada, Makoto|Aoki, Shinya|Yatomi, Yutaka|Takuwa, Yoh|Nagawa, Hirokazu
PMID: 16183075
Journal: Front Biosci. 2006 May 1;11:1924-31.
Title: Analysis of common gene expression patterns in four human tumor cell lines exposed to camptothecin using cDNA microarray: identification of topoisomerase-mediated DNA damage response pathways.
Author: Guo, XueQing|Zhang, JunPing|Fu, XuPing|Wei, Qing|Lu, YingHua|Li, Yao|Yin, Gang|Mao, YuMin|Xie, Yi|Rui, YaoCheng|Ying, Kang
PMID: 16368568
Journal: J Biol Chem. 2006 Feb 24;281(8):4564-9.
Title: Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells.
Author: Thiel, Alexandra|Heinonen, Mira|Rintahaka, Johanna|Hallikainen, Tuija|Hemmes, Annabrita|Dixon, Dan A|Haglund, Caj|Ristimaki, Ari
PMID: 16371352
Journal: Cancer Res. 2006 Feb 15;66(4):2181-7.
Title: Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer.
Author: Yasumoto, Kazuo|Koizumi, Keiichi|Kawashima, Atsuhiro|Saitoh, Yurika|Arita, Yoshihisa|Shinohara, Kanna|Minami, Takayuki|Nakayama, Takashi|Sakurai, Hiroaki|Takahashi, Yutaka|Yoshie, Osamu|Saiki, Ikuo
PMID: 16489019
Journal: Dig Liver Dis. 2006 May;38(5):310-8. Epub 2006 Mar 9.
Title: Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells.
Author: Liu, S-Q|Yu, J-P|Yu, H-G|Lv, P|Chen, H-l
PMID: 16527552
Journal: Cancer Biol Ther. 2006 Apr;5(4):371-4. Epub 2006 Apr 30.
Title: How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions.
Author: Vogiatzi, Paraskevi|De Falco, Giulia|Claudio, Pier Paolo|Giordano, Antonio
PMID: 16627973
Journal: Digestion. 2006;73(2-3):75-83. Epub 2006 Apr 19.
Title: Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells.
Author: Fan, Xiao Ming|Jiang, Xiao Hua|Gu, Qing|Ching, Yick Pang|He, Hua|Xia, Harry H X|Lin, Marie Chia Mi|Chan, Annie O O|Yuen, Man Fung|Kung, Hsiang-Fu|Wong, Benjamin Chun-Yu
PMID: 16641552
Journal: Cancer Res. 2006 May 15;66(10):4991-5.
Title: Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1.
Author: Bae, In Hwa|Park, Myung-Jin|Yoon, Sung Hwan|Kang, Sung Wook|Lee, Seung-Sook|Choi, Kyung-Mi|Um, Hong-Duck
PMID: 16707418
Journal: Pathobiology. 2006;73(1):8-17.
Title: Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma.
Author: Kobayashi, Iwao|Semba, Shuho|Matsuda, Yoshiko|Kuroda, Yoshikazu|Yokozaki, Hiroshi
PMID: 16785763
Journal: Mol Cells. 2006 Jun 30;21(3):367-75.
Title: CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS.
Author: Shim, Hyeeun|Shim, Eunsook|Lee, Hansoo|Hahn, Janghee|Kang, Dongmin|Lee, Yun-Sil|Jeoung, Dooil
PMID: 16819299
Journal: Int J Oncol. 2006 Sep;29(3):549-55.
Title: CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway.
Author: Ardyanto, Tonang Dwi|Osaki, Mitsuhiko|Tokuyasu, Naruo|Nagahama, Yumi|Ito, Hisao
PMID: 16865270
Journal: Life Sci. 2006 Oct 12;79(20):1956-62.
Title: Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell lines.
Author: Kwon, Mi-Jin|Nam, Taek-Jeong
PMID: 16876203
Journal: J Clin Oncol. 2006 Sep 10;24(26):4309-16.
Title: Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma.
Author: Rojo, Federico|Tabernero, Josep|Albanell, Joan|Van Cutsem, Eric|Ohtsu, Atsushi|Doi, Toshihiko|Koizumi, Wasaburo|Shirao, Kuniaki|Takiuchi, Hiroya|Ramon y Cajal, S|Baselga, Jose
PMID: 16963731
Journal: Biomed Environ Sci. 2006 Aug;19(4):285-91.
Title: Induction of apoptosis by L-NMMA, via FKHRL1/ROCK pathway in human gastric cancer cells.
Author: Wang, Yong-Zhong|Feng, Zhen-Qing
PMID: 17044646
Journal: Oncology. 2006;70(4):285-9. Epub 2006 Oct 16.
Title: Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas.
Author: Soung, Young Hwa|Lee, Jong Woo|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 17047397
Journal: J Clin Oncol. 2006 Oct 20;24(30):4922-7.
Title: Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Author: Dragovich, Tomislav|McCoy, Sheryl|Fenoglio-Preiser, Cecilia M|Wang, Jiang|Benedetti, Jacqueline K|Baker, Amanda F|Hackett, Christopher B|Urba, Susan G|Zaner, Ken S|Blanke, Charles D|Abbruzzese, James L
PMID: 17050876
Journal: Br J Cancer. 2006 Dec 4;95(11):1504-13. Epub 2006 Nov 7.
Title: Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis.
Author: Yokoyama, H|Ikehara, Y|Kodera, Y|Ikehara, S|Yatabe, Y|Mochizuki, Y|Koike, M|Fujiwara, M|Nakao, A|Tatematsu, M|Nakanishi, H
PMID: 17088902
Journal: Gastroenterology. 2006 Nov;131(5):1530-41.
Title: A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer.
Author: Nakamura, Kazunori|Yashiro, Masakazu|Matsuoka, Tasuku|Tendo, Masashige|Shimizu, Toshiyuki|Miwa, Atsushi|Hirakawa, Kosei
PMID: 17101326
Journal: J Exp Clin Cancer Res. 2006 Dec;25(4):601-6.
Title: Reversal of multidrug resistance of gastric cancer cells by downregulation of Akt1 with Akt1 siRNA.
Author: Han, Z|Hong, L|Wu, K|Han, S|Shen, H|Liu, C|Han, Y|Liu, Z|Han, Y|Fan, D
PMID: 17310852
Journal: Mol Carcinog. 2007 Feb;46(2):155-64.
Title: Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway.
Author: Sawabu, Tateo|Seno, Hiroshi|Kawashima, Tomoko|Fukuda, Akihisa|Uenoyama, Yoshito|Kawada, Mayumi|Kanda, Naoki|Sekikawa, Akira|Fukui, Hirokazu|Yanagita, Motoko|Yoshibayashi, Hiroshi|Satoh, Seiji|Sakai, Yoshiharu|Nakano, Toru|Chiba, Tsutomu
PMID: 17186543
Journal: Cancer Lett. 2007 Jun 28;251(2):268-77.
Title: Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway.
Author: Pang, Rui-Ping|Zhou, Jia-Guo|Zeng, Zhi-Rong|Li, Xiao-Yan|Chen, Wei|Chen, Min-Hu|Hu, Pin-Jin
PMID: 17257745
Journal: Gastric Cancer. 2007;10(1):45-51.
Title: Expression of phosphorylated Akt (pAkt) in gastric carcinoma predicts prognosis and efficacy of chemotherapy.
Author: Murakami, Daiki|Tsujitani, Shunichi|Osaki, Tomohiro|Saito, Hiroaki|Katano, Kuniyuki|Tatebe, Shigeru|Ikeguchi, Masahide
PMID: 17334718
Journal: Cell Biol Int. 2007 Aug;31(8):768-75.
Title: A polysaccharide of the marine alga Capsosiphon fulvescens induces apoptosis in AGS gastric cancer cells via an IGF-IR-mediated PI3K/Akt pathway.
Author: Kwon, Mi-Jin|Nam, Taek-Jeong
PMID: 17344071
Journal: Mol Cancer Ther. 2007 Mar;6(3):1123-32.
Title: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Author: Lang, Sven A|Klein, Dagmar|Moser, Christian|Gaumann, Andreas|Glockzin, Gabriel|Dahlke, Marc H|Dietmaier, Wolfgang|Bolder, Ulrich|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17363505
Journal: FASEB J. 2007 Jul;21(9):2247-56.
Title: Cellular prion protein promotes proliferation and G1/S transition of human gastric cancer cells SGC7901 and AGS.
Author: Liang, Jie|Pan, Yanglin|Zhang, Dexin|Guo, Changcun|Shi, Yongquan|Wang, Jingbo|Chen, Yu|Wang, Xin|Liu, Jie|Guo, Xuegang|Chen, Zheng|Qiao, Taidong|Fan, Daiming
PMID: 17409275
Journal: Cancer Biol Ther. 2007 May;6(5):686-90. Epub 2007 Feb 3.
Title: Defibrotide: an endothelium protecting and stabilizing drug, has an anti-angiogenic potential in vitro and in vivo.
Author: Koehl, Gudrun E|Geissler, Edward K|Iacobelli, Massimo|Frei, Caroline|Burger, Verena|Haffner, Silvia|Holler, Ernst|Andreesen, Reinhard|Schlitt, Hans J|Eissner, Gunther
PMID: 17495522
Journal: Clin Cancer Res. 2007 May 15;13(10):3051-7.
Title: AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor.
Author: Takeda, Masayuki|Arao, Tokuzo|Yokote, Hideyuki|Komatsu, Teruo|Yanagihara, Kazuyoshi|Sasaki, Hiroki|Yamada, Yasuhide|Tamura, Tomohide|Fukuoka, Kazuya|Kimura, Hiroshi|Saijo, Nagahiro|Nishio, Kazuto
PMID: 17505008
Journal: J Natl Cancer Inst. 2007 Jun 20;99(12):949-61.
Title: Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
Author: Oh, Seung Hyun|Woo, Jong Kyu|Yazici, Yasemin Dakak|Myers, Jeffrey N|Kim, Woo-Young|Jin, Quanri|Hong, Soon Sun|Park, Hyun-Ju|Suh, Young-Ger|Kim, Kyu-Won|Hong, Waun Ki|Lee, Ho-Young
PMID: 17565155
Journal: Cancer Biol Ther. 2007 Jun;6(6):832-9. Epub 2007 Mar 26.
Title: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
Author: Katoh, Masaru
PMID: 17568183
Journal: J Virol. 2007 Sep;81(17):9299-306.
Title: Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.
Author: Fukuda, Makoto|Longnecker, Richard
PMID: 17582000
Journal: J Pharmacol Exp Ther. 2007 Oct;323(1):365-73. Epub 2007 Jul 23.
Title: Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells.
Author: Lin, Heng-Liang|Chiou, Shih-Hwa|Wu, Chew-Wun|Lin, Wen-Bin|Chen, Li-Hsin|Yang, Yi-Ping|Tsai, Ming-Long|Uen, Yih-Huei|Liou, Jing-Ping|Chi, Chin-Wen
PMID: 17646428
Journal: World J Gastroenterol. 2007 Jul 7;13(25):3517-22.
Title: RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway.
Author: Sun, Hua-Wen|Tong, Shi-Lun|He, Jie|Wang, Qi|Zou, Li|Ma, Shu-Jing|Tan, Hai-Yan|Luo, Jian-Fei|Wu, Hong-Xue
PMID: 17659701
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Aug;24(4):387-91.
Title: [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines].
Author: Sun, Dan-feng|Fang, Jing-yuan|Zhang, Yan-jie|Tian, Xiao-qing|Zhu, Hong-yin|Li, En-ling|Gu, Wei-qi|Shen, Guan-feng
PMID: 17680526
Journal: Int J Cancer. 2007 Dec 1;121(11):2547-55.
Title: 2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer.
Author: Lin, Heng-Liang|Yang, Muh-Hwa|Wu, Chew-Wun|Chen, Po-Min|Yang, Yi-Ping|Chu, Yue-Ru|Kao, Chung-Lan|Ku, Hung-Hai|Lo, Jen-Fan|Liou, Jing-Ping|Chi, Chin-Wen|Chiou, Shih-Hwa
PMID: 17680560
Journal: J Exp Clin Cancer Res. 2007 Jun;26(2):261-8.
Title: Phospho Akt mediates multidrug resistance of gastric cancer cells through regulation of P-gp, Bcl-2 and Bax.
Author: Han, Z|Hong, L|Han, Y|Wu, K|Han, S|Shen, H|Li, C|Yao, L|Qiao, T|Fan, D
PMID: 17725107
Journal: Anticancer Drugs. 2007 Jul;18(6):677-86.
Title: Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells.
Author: Fujita, Takeo|Doihara, Hiroyoshi|Washio, Kazuhiro|Ino, Hideo|Murakami, Masakazu|Naito, Minoru|Shimizu, Nobuyoshi
PMID: 17762396
Journal: Planta Med. 2007 Sep;73(11):1176-81. Epub 2007 Sep 7.
Title: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells.
Author: Jiang, Tiejun|Zhu, Yongliang|Luo, Cong|Lu, Xiaoyong|Zhang, Wo|Qiu, Fuming|Huang, Jian
PMID: 17823871
Journal: Mol Cancer Res. 2007 Nov;5(11):1111-23.
Title: Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2.
Author: Lin, Been-Ren|Chang, Cheng-Chi|Chen, Li-Ro|Wu, Ming-Hsun|Wang, Ming-Yang|Kuo, I-Hsin|Chu, Chia-Yu|Chang, King-Jen|Lee, Po-Huang|Chen, Wei-Jao|Kuo, Min-Liang|Lin, Ming-Tsan
PMID: 18025257
Journal: Int J Cancer. 2008 Jan 15;122(2):433-43.
Title: Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death.
Author: Yu, Hong-Gang|Ai, Yao-Wei|Yu, Liang-Liang|Zhou, Xiao-Dong|Liu, Jin|Li, Jun-Hua|Xu, Xi-Ming|Liu, Song|Chen, Jing|Liu, Fen|Qi, Yuan-Ling|Deng, Quanjun|Cao, Jun|Liu, Shi-Quan|Luo, He-Sheng|Yu, Jie-Ping
PMID: 17935137
Journal: Carcinogenesis. 2008 Jan;29(1):44-51.
Title: A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.
Author: Lee, Byung Lan|Kim, Woo Ho|Jung, Jieun|Cho, Sung Jin|Park, Jong-Wan|Kim, Jihyen|Chung, Hee-Yong|Chang, Mee Soo|Nam, Seon Young
PMID: 17984117
Journal: Carcinogenesis. 2008 Jan;29(1):76-83. Epub 2007 Nov 16.
Title: REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells.
Author: Sekikawa, Akira|Fukui, Hirokazu|Fujii, Shigehiko|Ichikawa, Kazuhito|Tomita, Shigeki|Imura, Johji|Chiba, Tsutomu|Fujimori, Takahiro
PMID: 18024479
Journal: Int J Oncol. 2008 Jan;32(1):89-95.
Title: Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin.
Author: Kim, Sun Young|Kim, Hwang Phill|Kim, Yu Jung|Oh, Do Youn|Im, Seock-Ah|Lee, Dongsoon|Jong, Hyun-Soon|Kim, Tae-You|Bang, Yung-Jue
PMID: 18097546
Journal: Cancer Res. 2008 Jan 15;68(2):395-403.
Title: t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism.
Author: Belkhiri, Abbes|Dar, Altaf A|Zaika, Alexander|Kelley, Mark|El-Rifai, Wael
PMID: 18199533
Journal: Cancer Lett. 2008 Apr 18;262(2):223-31.
Title: Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells.
Author: Zhao, Qing|Yang, Yong|Yu, Jun|You, Qi-Dong|Zeng, Shi|Gu, Hong-Yan|Lu, Na|Qi, Qi|Liu, Wei|Wang, Xiao-Tang|Guo, Qing-Long
PMID: 18226852
Journal: Carcinogenesis. 2008 Apr;29(4):704-12.
Title: Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.
Author: Kim, Kwang-Kyu|Lee, Jung Joon|Yang, Young|You, Kwan-Hee|Lee, Jeong-Hyung
PMID: 18258606
Journal: Cancer Res. 2008 Mar 15;68(6):1916-26.
Title: Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells.
Author: Lee, Keun-Wook|Kim, Sang Gyun|Kim, Hwang-Phill|Kwon, Euna|You, Jiran|Choi, Hyung-Jun|Park, Jung-Hyun|Kang, Byeong-Cheol|Im, Seock-Ah|Kim, Tae-You|Kim, Woo Ho|Bang, Yung-Jue
PMID: 18339873
Journal: Eur J Cancer. 2008 May;44(7):1022-9.
Title: Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells.
Author: Hashimoto, Isaya|Koizumi, Keiichi|Tatematsu, Mikiko|Minami, Takayuki|Cho, Seiji|Takeno, Nobuhiro|Nakashima, Akitoshi|Sakurai, Hiroaki|Saito, Shigeru|Tsukada, Kazuhiro|Saiki, Ikuo
PMID: 18375114
Journal: Life Sci. 2008 Apr 23;82(17-18):956-63.
Title: Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2.
Author: Lu, Na|Gao, Ying|Ling, Yun|Chen, Yan|Yang, Yong|Gu, Hong-Yan|Qi, Qi|Liu, Wei|Wang, Xiao-Tang|You, Qi-Dong|Guo, Qing-Long
PMID: 18378261
Journal: Cancer Lett. 2008 Jul 8;265(2):197-205.
Title: Inhibition of the PI3K-Akt/PKB survival pathway enhanced an ethanol extract of Rhus verniciflua Stokes-induced apoptosis via a mitochondrial pathway in AGS gastric cancer cell lines.
Author: Kim, Ji Hye|Go, Ho Yeon|Jin, Dong Hoon|Kim, Hwang-Phill|Hong, Myung Hee|Chung, Woo-Yeop|Park, Jong-Hyeong|Jang, Jun Bock|Jung, Hee|Shin, Yong Cheol|Kim, Sung-Hoon|Ko, Seong-Gyu
PMID: 18378393
Journal: Dig Dis Sci. 2008 Jul;53(7):1801-10.
Title: Akt1/protein kinase B alpha is involved in gastric cancer progression and cell proliferation.
Author: Han, Zheyi|Wu, Kaichun|Shen, Huiqin|Li, Chunying|Han, Shuang|Hong, Liu|Shi, Yongquan|Liu, Na|Guo, Changcun|Xue, Yan|Qiao, Taidong|Fan, Daiming
PMID: 18379876
Journal: J Biol Chem. 2008 Jun 6;283(23):15807-15.
Title: Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.
Author: Lin, Ming-Tsan|Kuo, I-Hsin|Chang, Cheng-Chi|Chu, Chia-Yu|Chen, Hsing-Yu|Lin, Been-Ren|Sureshbabu, Munisamy|Shih, Hou-Jung|Kuo, Min-Liang
PMID: 18381294
Journal: Gastroenterology. 2008 Apr;134(4):1070-82.
Title: Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms.
Author: Subramaniam, Dharmalingam|Ramalingam, Satish|May, Randal|Dieckgraefe, Brian K|Berg, Douglas E|Pothoulakis, Charalabos|Houchen, Courtney W|Wang, Timothy C|Anant, Shrikant
PMID: 18395088
Journal: Food Chem Toxicol. 2008 Aug;46(8):2653-7.
Title: The effect of polysaccharide extracted from the marine alga Capsosiphon fulvescens on ethanol administration.
Author: Hwang, Hye-Jeong|Kwon, Mi-Jin|Kim, In-Hye|Nam, Taek-Jeong
PMID: 18524446
Journal: Electrophoresis. 2008 Aug;29(15):3192-200.
Title: Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway.
Author: Fukagawa, Yuki|Nishikawa, Jun|Kuramitsu, Yasuhiro|Iwakiri, Dai|Takada, Kenzo|Imai, Shousuke|Satake, Masaaki|Okamoto, Takeshi|Fujimoto, Masanori|Okita, Kiwamu|Nakamura, Kazuyuki|Sakaida, Isao
PMID: 18604870
Journal: Sci China C Life Sci. 2008 Jul;51(7):640-7.
Title: Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines.
Author: Sun, Danfeng|Toan, Xiaoqing|Zhang, Yanjie|Chen, Yingxuan|Lu, Rong|Wang, Xia|Fang, Jingyuan
PMID: 18622747
Journal: Cancer Lett. 2008 Dec 8;272(1):148-59.
Title: A small interfering RNA targeting osteopontin as gastric cancer therapeutics.
Author: Gong, Mouchun|Lu, Zhengmao|Fang, Guoen|Bi, Jianwei|Xue, Xuchao
PMID: 18694621
Journal: Carcinogenesis. 2008 Nov;29(11):2078-88.
Title: Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria.
Author: Chen, Hang-Zi|Zhao, Bi-Xing|Zhao, Wen-Xiu|Li, Li|Zhang, Bing|Wu, Qiao
PMID: 18713840
Journal: Gastroenterology. 2008 Dec;135(6):2030-42, 2042.e1-3.
Title: NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis.
Author: Kang, Min-Ju|Ryu, Byung-Kyu|Lee, Min-Goo|Han, Jikhyon|Lee, Jin-Hee|Ha, Tae-Kyu|Byun, Do-Sun|Chae, Kwon-Seok|Lee, Bong-Hee|Chun, Hyang Sook|Lee, Kil Yeon|Kim, Hyo-Jong|Chi, Sung-Gil
PMID: 18824170
Journal: Biochem Pharmacol. 2008 Dec 15;76(12):1705-15.
Title: Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH2-terminal kinase pathway in human gastric cancer cell line MGC-803.
Author: Qian, Xia|Li, Jing|Ding, Jianhua|Wang, Zhiyuan|Duan, Lei|Hu, Gang
PMID: 18840412
Journal: Virchows Arch. 2008 Nov;453(5):449-55.
Title: Activated Akt as an indicator of prognosis in gastric cancer.
Author: Cinti, Caterina|Vindigni, Carla|Zamparelli, Alessandra|La Sala, Dario|Epistolato, Maria Carmela|Marrelli, Daniele|Cevenini, Gabriele|Tosi, Piero
PMID: 18841391
Journal: Exp Biol Med (Maywood). 2008 Dec;233(12):1537-45.
Title: Osteopontin prevents curcumin-induced apoptosis and promotes survival through Akt activation via alpha v beta 3 integrins in human gastric cancer cells.
Author: Song, Gang|Ming, Yanlin|Mao, Yubin|Bao, Shideng|Ouyang, Gaoliang
PMID: 18849546
Journal: Mol Cancer Ther. 2008 Nov;7(11):3499-508.
Title: HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.
Author: Bachleitner-Hofmann, Thomas|Sun, Mark Y|Chen, Chin-Tung|Tang, Laura|Song, Lin|Zeng, Zhaoshi|Shah, Manish|Christensen, James G|Rosen, Neal|Solit, David B|Weiser, Martin R
PMID: 18974395
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Jul;30(7):494-7.
Title: [Impact of PI3K /Akt /mdm2 signaling pathway on the sensitivity of gastric cancer cell line SGC7901 to doxorubicin].
Author: Ai, Yao-Wei|Yu, Hong-Gang|Yu, Jie-Ping|Yang, Yan|Li, Huan|Hu, Xiao-Wen|Luo, He-Sheng
PMID: 19062713
Journal: Mol Cell Proteomics. 2009 Jan;8(1):70-85.
Title: Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway.
Author: Liu, Rui|Li, Zhenjun|Bai, Shujun|Zhang, Haiyuan|Tang, Minghai|Lei, Yunlong|Chen, Lijuan|Liang, Shufang|Zhao, Ying-Lan|Wei, Yuquan|Huang, Canhua
PMID: 18723843
Journal: Cell Microbiol. 2009 Jan;11(1):70-82.
Title: Helicobacter pylori activate epidermal growth factor receptor- and phosphatidylinositol 3-OH kinase-dependent Akt and glycogen synthase kinase 3beta phosphorylation.
Author: Tabassam, Fazal H|Graham, David Y|Yamaoka, Yoshio
PMID: 18782353
Journal: J Gastroenterol Hepatol. 2009 Mar;24(3):480-7.
Title: Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling.
Author: Kim, Nayoung|Kim, Chung Hyun|Ahn, Dong-Won|Lee, Kyoung Soo|Cho, Soo-Jeong|Park, Ji Hyun|Lee, Mi Kyoung|Kim, Joo Sung|Jung, Hyun Chae|Song, In Sung
PMID: 18823436
Journal: J Biol Chem. 2009 Jan 16;284(3):1612-9.
Title: Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway.
Author: Nakayama, Masaaki|Hisatsune, Junzo|Yamasaki, Eiki|Isomoto, Hajime|Kurazono, Hisao|Hatakeyama, Masanori|Azuma, Takeshi|Yamaoka, Yoshio|Yahiro, Kinnosuke|Moss, Joel|Hirayama, Toshiya
PMID: 18996844
Journal: Mol Cell Biol. 2009 Jan;29(2):402-13.
Title: A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.
Author: Tanaka, Masamitsu|Sasaki, Kazuki|Kamata, Reiko|Hoshino, Yukari|Yanagihara, Kazuyoshi|Sakai, Ryuichi
PMID: 19015244
Journal: Int J Oncol. 2009 Jan;34(1):25-32.
Title: Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation.
Author: Patel, Dipa|Bassi, Rajiv|Hooper, Andrea|Prewett, Marie|Hicklin, Daniel J|Kang, Xiaoqiang
PMID: 19082474
Journal: Cancer Lett. 2009 May 8;277(1):22-8.
Title: Signaling components involved in Bcl-w-induced migration of gastric cancer cells.
Author: Bae, In Hwa|Yoon, Sung Hwan|Lee, Seung Bum|Park, Jong Kuk|Ho, Jin-Nyoung|Um, Hong-Duck
PMID: 19097687
Journal: Cell Prolif. 2009 Feb;42(1):110-21.
Title: Reg IV enhances peritoneal metastasis in gastric carcinomas.
Author: Kuniyasu, H|Oue, N|Sasahira, T|Yi, L|Moriwaka, Y|Shimomoto, T|Fujii, K|Ohmori, H|Yasui, W
PMID: 19143768
Journal: FEBS J. 2009 Feb;276(3):685-94.
Title: Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.
Author: Liang, Jie|Ge, Fulin|Guo, Changcun|Luo, Guanhong|Wang, Xin|Han, Guohong|Zhang, Dexin|Wang, Jianhong|Li, Kai|Pan, Yanglin|Yao, Liping|Yin, Zhanxin|Guo, Xuegang|Wu, Kaichun|Ding, Jie|Fan, Daiming
PMID: 19143835
Journal: Int J Oncol. 2009 Feb;34(2):473-80.
Title: Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer.
Author: Lee, Hyo Jin|Kim, Seong Woo|Kim, Ha Yon|Li, Shengjin|Yun, Hwan Jung|Song, Kyu Sang|Kim, Samyong|Jo, Deog Yeon
PMID: 19148483
Journal: Endocr Relat Cancer. 2009 Jun;16(2):599-611.
Title: Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
Author: Alvarez, Carlos J P|Lodeiro, Maria|Theodoropoulou, Marily|Camina, Jesus P|Casanueva, Felipe F|Pazos, Yolanda
PMID: 19153210
Journal: Cell Host Microbe. 2009 Jan 22;5(1):23-34.
Title: Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation.
Author: Suzuki, Masato|Mimuro, Hitomi|Kiga, Kotaro|Fukumatsu, Makoto|Ishijima, Nozomi|Morikawa, Hanako|Nagai, Shigenori|Koyasu, Shigeo|Gilman, Robert H|Kersulyte, Dangeruta|Berg, Douglas E|Sasakawa, Chihiro
PMID: 19154985
Journal: J Infect Dis. 2009 Mar 1;199(5):641-51.
Title: Helicobacter pylori regulates cellular migration and apoptosis by activation of phosphatidylinositol 3-kinase signaling.
Author: Nagy, Toni A|Frey, Mark R|Yan, Fang|Israel, Dawn A|Polk, D Brent|Peek, Richard M Jr
PMID: 19199544
Journal: Br J Cancer. 2009 Mar 10;100(5):782-8.
Title: Relation between outcomes and localisation of p-mTOR expression in gastric cancer.
Author: Murayama, T|Inokuchi, M|Takagi, Y|Yamada, H|Kojima, K|Kumagai, J|Kawano, T|Sugihara, K
PMID: 19223902
Journal: Cell Mol Biol Lett. 2009;14(3):466-80.
Title: The expression of protein kinase B in gastric cancer cell apoptosis induced by 12-O-tetradecanoylphorbol-1, 3-acetate.
Author: Zhang, Bing|Xia, Chun
PMID: 19238332
Journal: Cancer Lett. 2009 Jul 8;279(2):137-44.
Title: Midkine positively regulates the proliferation of human gastric cancer cells.
Author: Xu, Yingying|Qu, Xiujuan|Zhang, Xue|Luo, Yang|Zhang, Ye|Luo, Ying|Hou, Kezuo|Liu, Yunpeng
PMID: 19250738
Journal: J Pathol. 2009 Jun;218(2):248-55.
Title: Reversal of P-glycoprotein-mediated multi-drug resistance by the E3 ubiquitin ligase Cbl-b in human gastric adenocarcinoma cells.
Author: Zhang, Ye|Qu, Xiujuan|Hu, Xuejun|Yang, Xianghong|Hou, Kezuo|Teng, Yuee|Zhang, Jingdong|Sada, Kiyonao|Liu, Yunpeng
PMID: 19274672
Journal: Anticancer Drugs. 2009 Jan;20(1):59-64.
Title: PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells.
Author: Li, Dan|Qu, Xiujuan|Hou, Kezuo|Zhang, Ye|Dong, Qian|Teng, Yuee|Zhang, Jingdong|Liu, Yunpeng
PMID: 19343001
Journal: Int J Oncol. 2009 May;34(5):1181-9.
Title: Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle.
Author: Nakamura, Junya|Aoyagi, Sayaka|Nanchi, Isamu|Nakatsuka, Shin-Ichi|Hirata, Erika|Shibata, Shohei|Fukuda, Mari|Yamamoto, Yumiko|Fukuda, Ikuyo|Tatsumi, Naoya|Ueda, Tazu|Fujiki, Fumihiro|Nomura, Masaya|Nishida, Sumiyuki|Shirakata, Toshiaki|Hosen, Naoki|Tsuboi
PMID: 19360331
Journal: J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66.
Title: Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
Author: Arkenau, Hendrik-Tobias
PMID: 19363621
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Cancer Lett. 2009 Nov 1;284(2):208-15.
Title: Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation.
Author: Li, Yingchun|Qu, Xiujuan|Qu, Jinglei|Zhang, Ye|Liu, Jing|Teng, Yuee|Hu, Xuejun|Hou, Kezuo|Liu, Yunpeng
PMID: 19457607
Journal: Dig Liver Dis. 2009 Dec;41(12):875-80.
Title: Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation.
Author: Qu, J-L|Qu, X-J|Zhao, M-F|Teng, Y-E|Zhang, Y|Hou, K-Z|Jiang, Y-H|Yang, X-H|Liu, Y-P
PMID: 19473897
Journal: J Exp Clin Cancer Res. 2009 Jun 4;28:73.
Title: Reactive oxygen species regulate urokinase plasminogen activator expression and cell invasion via mitogen-activated protein kinase pathways after treatment with hepatocyte growth factor in stomach cancer cells.
Author: Lee, Kyung Hee|Kim, Sang Woon|Kim, Jae-Ryong
PMID: 19497102
Journal: FEBS Lett. 2009 Jul 7;583(13):2255-62.
Title: Ubiquitin ligase Cbl-b sensitizes leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals.
Author: Qu, Xiujuan|Zhang, Ye|Li, Yingchun|Hu, Xuejun|Xu, Yingying|Xu, Ling|Hou, Kezou|Sada, Kiyonao|Liu, Yunpeng
PMID: 19508871
Journal: Int J Oncol. 2009 Jul;35(1):187-92.
Title: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 19513567
Journal: World J Gastroenterol. 2009 Jun 21;15(23):2870-7.
Title: Alisol B acetate induces apoptosis of SGC7901 cells via mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways.
Author: Xu, Yong-Hong|Zhao, Li-Jie|Li, Yan
PMID: 19533808
Journal: BMC Cancer. 2009 Jun 23;9:198.
Title: A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth.
Author: Mita, Hiroaki|Toyota, Minoru|Aoki, Fumio|Akashi, Hirofumi|Maruyama, Reo|Sasaki, Yasushi|Suzuki, Hiromu|Idogawa, Masashi|Kashima, Lisa|Yanagihara, Kazuyoshi|Fujita, Masahiro|Hosokawa, Masao|Kusano, Masanobu|Sabau, Sorin Vasile|Tatsumi, Haruyuki|Imai, Kohzo
PMID: 19545448
Journal: Ai Zheng. 2009 Feb;28(2):97-9. Epub 2009 Feb 23.
Title: Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR.
Author: Zhang, Ye|Qu, Xiu-Juan|Liu, Yun-Peng|Yang, Xiang-Hong|Hou, Ke-Zuo|Teng, Yue-E|Zhang, Jing-Dong
PMID: 19550116
Journal: J Cell Mol Med. 2009 Aug;13(8B):1706-18.
Title: Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation.
Author: Song, Gang|Ouyang, Gaoliang|Mao, Yubin|Ming, Yanlin|Bao, Shideng|Hu, Tianhui
PMID: 19602039
Journal: Mol Cancer Ther. 2009 Sep;8(9):2537-45.
Title: AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer.
Author: Yang, Shu|Ngo, Van Chanh|Lew, Guo Bin|Chong, Lih Wen Valerie|Lee, Swee Shean|Ong, Wei Jie Richard|Lam, Wei Ling Irene|Thng, Choon Hua|Koong, Heng Nung|Ong, Hock Soo|Chung, Alexander|Chow, Pierce|Lee, Jonathan|Soo, Khee Chee|Huynh, Hung
PMID: 19723882
Journal: Mol Cancer Ther. 2009 Sep;8(9):2526-36.
Title: Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells.
Author: Yoon, Young-Kwang|Kim, Hwang-Phill|Han, Sae-Won|Hur, Hyung-Seok|Oh, Do Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 19755509
Journal: Hum Pathol. 2009 Dec;40(12):1790-7.
Title: Overexpression of YKL-40 is an independent prognostic marker in gastric cancer.
Author: Bi, Jiong|Lau, Sze-Hang|Lv, Zi-Li|Xie, Dan|Li, Wen|Lai, Ying-Rong|Zhong, Jue-Min|Wu, Hui-qun|Su, Qiao|He, Yu-long|Zhan, Wen-Hua|Wen, Jian-Ming|Guan, Xin-Yuan
PMID: 19765801
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Acta Oncol. 2009;48(8):1173-80.
Title: The role of cbl family of ubiquitin ligases in gastric cancer exosome-induced apoptosis of Jurkat T cells.
Author: Qu, Jing-Lei|Qu, Xiu-Juan|Qu, Jing-Lei|Qu, Xiu-Juan|Zhao, Ming-Fang|Teng, Yue-E|Zhang, Ye|Hou, Ke-Zuo|Jiang, You-Hong|Yang, Xiang-Hong|Liu, Yun-Peng
PMID: 19863226
Journal: Oncol Rep. 2009 Dec;22(6):1305-13.
Title: Suppression of Akt1 expression by small interference RNA inhibits SGC7901 cell growth in vitro and in vivo.
Author: Cui, Xiao-Wei|Zhao, Feng-Juan|Liu, Jian|Song, Xiao-Mei|Xu, Peng|Zhou, Xuan|Zhang, Jie|Wang, Tao|Kang, Chun-Sheng|Zhang, Qing-Yu
PMID: 19885581
Journal: Molecules. 2009 Oct 26;14(11):4300-11.
Title: Silibinin suppresses TNF-alpha-induced MMP-9 expression in gastric cancer cells through inhibition of the MAPK pathway.
Author: Kim, Sangmin|Choi, Min Gew|Lee, Hye Sook|Lee, Se Kyung|Kim, Sung Hoon|Kim, Wan Wook|Hur, Sung Mo|Kim, Jung-Han|Choe, Jun-Ho|Nam, Seok Jin|Yang, Jung-Hyun|Kim, Sung|Lee, Jeong Eon|Kim, Jee Soo
PMID: 19924065
Journal: World J Gastroenterol. 2009 Nov 28;15(44):5541-8.
Title: Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway.
Author: Li, Guo-Qing|Xie, Juan|Lei, Xiao-Yong|Zhang, Li
PMID: 19938192
Journal: Mol Biol Rep. 2010 Jun;37(5):2189-98.
Title: Overexpression of PIP5KL1 suppresses cell proliferation and migration in human gastric cancer cells.
Author: Shi, Lan|Zhao, Mei|Luo, Qing|Ma, Yi-Ming|Zhong, Jia-Ling|Yuan, Xing-Hua|Huang, Chang-Zhi
PMID: 19680787
Journal: Hum Pathol. 2010 Jan;41(1):59-69.
Title: The role of Reg IV gene and its encoding product in gastric carcinogenesis.
Author: Zheng, Hua-Chuan|Xu, Xiao-Yan|Yu, Miao|Takahashi, Hiroyuki|Masuda, Shinji|Takano, Yasuo
PMID: 19740514
Journal: Exp Cell Res. 2010 Jan 1;316(1):24-37.
Title: BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway.
Author: Kang, Myoung Hee|Kim, Jun Suk|Seo, Ji Eun|Oh, Sang Cheul|Yoo, Young A
PMID: 19835871
Journal: Int J Cancer. 2010 Sep 1;127(5):1197-208.
Title: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways.
Author: Lyros, Orestis|Mueller, Annett|Heidel, Florian|Schimanski, Carl C|Gockel, Ines|Galle, Peter R|Lang, Hauke|Moehler, Markus
PMID: 20039326
Journal: Tohoku J Exp Med. 2010 Jan;220(1):3-14.
Title: Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA.
Author: Isomoto, Hajime|Moss, Joel|Hirayama, Toshiya
PMID: 20046046
Journal: Cancer Res. 2010 Feb 15;70(4):1524-33.
Title: MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Author: Pan, Bo-Sheng|Chan, Grace K Y|Chenard, Melissa|Chi, An|Davis, Lenora J|Deshmukh, Sujal V|Gibbs, Jackson B|Gil, Susana|Hang, Gaozhen|Hatch, Harold|Jewell, James P|Kariv, Ilona|Katz, Jason D|Kunii, Kaiko|Lu, Wei|Lutterbach, Bart A|Paweletz, Cloud P|Qu, Xian
PMID: 20145145
Journal: Mol Cancer. 2010 Feb 21;9:40.
Title: BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.
Author: Zhang, Xiao-Wei|Sheng, Ya-Ping|Li, Qian|Qin, Wei|Lu, You-Wei|Cheng, Yu-Fan|Liu, Bing-Ya|Zhang, Feng-Chun|Li, Jin|Dimri, Goberdhan P|Guo, Wei-Jian
PMID: 20170541
Journal: Clin Cancer Res. 2010 Mar 1;16(5):1509-19.
Title: Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.
Author: Wainberg, Zev A|Anghel, Adrian|Desai, Amrita J|Ayala, Raul|Luo, Tong|Safran, Brent|Fejzo, Marlena S|Hecht, J Randolph|Slamon, Dennis J|Finn, Richard S
PMID: 20179222
Journal: Int J Oncol. 2010 Apr;36(4):1023-30.
Title: Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation.
Author: Cho, Il-Rae|Koh, Sang Seok|Min, Hye-Jin|Park, Eun-Hee|Srisuttee, Ratakorn|Jhun, Byung Hak|Kang, Chi Duk|Kim, Manbok|Johnston, Randal N|Chung, Young-Hwa
PMID: 20198349
Journal: Cancer Res. 2010 Mar 15;70(6):2339-49.
Title: MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta.
Author: Tsukamoto, Yoshiyuki|Nakada, Chisato|Noguchi, Tsuyoshi|Tanigawa, Masato|Nguyen, Lam Tung|Uchida, Tomohisa|Hijiya, Naoki|Matsuura, Keiko|Fujioka, Toshio|Seto, Masao|Moriyama, Masatsugu
PMID: 20215506
Journal: J Cell Biochem. 2010 May 15;110(2):321-32.
Title: Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells.
Author: Xian, Xiang-Shu|Park, Hyeyeon|Cho, Yu Kyung|Lee, In Seok|Kim, Sang Woo|Choi, Myung-Gyu|Chung, In-Sik|Han, Ki-Hwan|Park, Jae Myung
PMID: 20336665
Journal: Mol Carcinog. 2010 Apr;49(4):353-62.
Title: KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach.
Author: Yoon, Young-Kwang|Kim, Hwang-Phill|Han, Sae-Won|Oh, Do Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 20358631
Journal: Mol Cancer Ther. 2010 May;9(5):1188-97.
Title: Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition.
Author: Okamoto, Wataru|Okamoto, Isamu|Yoshida, Takeshi|Okamoto, Kunio|Takezawa, Ken|Hatashita, Erina|Yamada, Yuki|Kuwata, Kiyoko|Arao, Tokuzo|Yanagihara, Kazuyoshi|Fukuoka, Masahiro|Nishio, Kazuto|Nakagawa, Kazuhiko
PMID: 20406949
Journal: Oncol Rep. 2010 Jun;23(6):1735-45.
Title: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines.
Author: Luo, Hui-Yan|Wei, Wei|Shi, Yan-Xia|Chen, Xiao-Qin|Li, Yu-Hong|Wang, Feng|Qiu, Miao-Zhen|Li, Fang-Hua|Yan, Shu-Li|Zeng, Mu-Sheng|Huang, Peng|Xu, Rui-Hua
PMID: 20428833
Journal: Cell Mol Biol Lett. 2010 Sep;15(3):377-94.
Title: 12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis.
Author: Zhang, Bing|Xia, Chun
PMID: 20428959
Journal: J Dairy Sci. 2010 Jun;93(6):2344-50.
Title: Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Author: Xu, X X|Jiang, H R|Li, H B|Zhang, T N|Zhou, Q|Liu, N
PMID: 20494139
Journal: J Cell Biochem. 2010 Sep 1;111(1):218-28.
Title: PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
Author: Zheng, Tongsen|Meng, Xianzhi|Wang, Jiabei|Chen, Xi|Yin, Dalong|Liang, Yingjian|Song, Xuan|Pan, Shangha|Jiang, Hongchi|Liu, Lianxin
PMID: 20506484
Journal: Oncol Rep. 2010 Jul;24(1):89-95.
Title: Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway.
Author: Wen, Yu-Gang|Wang, Quan|Zhou, Chong-Zhi|Qiu, Guo-Qiang|Peng, Zhi-Hai|Tang, Hua-Mei
PMID: 20514448
Journal: Oncol Rep. 2010 Jul;24(1):113-9.
Title: Akt associates with nuclear factor kappaB and plays an important role in chemoresistance of gastric cancer cells.
Author: Yu, Liang-Liang|Dai, Ning|Yu, Hong-Gang|Sun, Lei-Min|Si, Jian-Min
PMID: 20514451
Journal: Biol Pharm Bull. 2010;33(6):931-7.
Title: Down-regulation of human epidermal growth factor receptor 2/neu oncogene by corosolic acid induces cell cycle arrest and apoptosis in NCI-N87 human gastric cancer cells.
Author: Lee, Myung Sun|Cha, Eun Young|Thuong, Phuong Thien|Kim, Ji Yeon|Ahn, Moon Sang|Sul, Ji Young
PMID: 20522955
Journal: J Gastroenterol Hepatol. 2010 May;25(5):935-41.
Title: 19-peptide, a fragment of tumstatin, inhibits the growth of poorly differentiated gastric carcinoma cells in vitro and in vivo.
Author: He, Yan|Jiang, Yang|Li, Ying-Jie|Liu, Xing-Han|Zhang, Lei|Liu, Li-Juan|Shi, Hang|Li, Hui-Ning|Ma, Yong-Cu|Jin, Xiao-Ming
PMID: 20546447
Journal: Gastroenterology. 2010 Oct;139(4):1333-43.
Title: Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells.
Author: Wei, Jinxiong|Nagy, Toni A|Vilgelm, Anna|Zaika, Elena|Ogden, Seth R|Romero-Gallo, Judith|Piazuelo, Maria B|Correa, Pelayo|Washington, Mary K|El-Rifai, Wael|Peek, Richard M|Zaika, Alexander
PMID: 20547161
Journal: Mol Diagn Ther. 2010 Jun 1;14(3):155-61.
Title: Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway.
Author: Wang, Wei-Qiang|Zhang, Hao|Wang, Hong-Bin|Sun, Yong-Gang|Peng, Zhi-Hong|Zhou, Gang|Yang, Shi-Ming|Wang, Rong-Quan|Fang, Dian-Chun
PMID: 20560677
Journal: Am J Pathol. 2010 Aug;177(2):955-63.
Title: Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer.
Author: Kubota, Eiji|Kataoka, Hiromi|Aoyama, Mineyoshi|Mizoshita, Tsutomu|Mori, Yoshinori|Shimura, Takaya|Tanaka, Mamoru|Sasaki, Makoto|Takahashi, Satoru|Asai, Kiyofumi|Joh, Takashi
PMID: 20566745
Journal: Cancer Invest. 2010 Dec;28(10):1038-47.
Title: The sequence-dependent cytotoxic effect of trastuzumab in combination with 5-Fluorouracil or cisplatin on gastric cancer cell lines.
Author: Li, Xiao-Ling|Yi, Shao-Qiong|Xu, Jian-Ming|Zhang, Yang|Yingying-Feng|Chen, Wei|Song, San-Tai
PMID: 20590442
Journal: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2508-16.
Title: Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals.
Author: Ho, Hsieh-Hsun|Chang, Chi-Sen|Ho, Wei-Chi|Liao, Sheng-You|Wu, Cheng-Hsun|Wang, Chau-Jong
PMID: 20600540
Journal: J Acupunct Meridian Stud. 2010 Mar;3(1):24-31.
Title: Induction of apoptosis by ethanol extracts of Ganoderma lucidum in human gastric carcinoma cells.
Author: Jang, Kyung-Jun|Han, Min-Ho|Lee, Byung-Hoon|Kim, Byung-Woo|Kim, Cheol-Hong|Yoon, Hyun-Min|Choi, Yung-Hyun
PMID: 20633512
Journal: BMC Cancer. 2010 Aug 13;10:425.
Title: LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.
Author: Shin, Jung-Young|Kim, Jeong-Oh|Lee, Suk Kyeong|Chae, Hiun-Suk|Kang, Jin-Hyoung
PMID: 20704765
Journal: Regul Pept. 2010 Dec 10;165(2-3):224-31.
Title: The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway.
Author: Patel, Oneel|Marshall, Kathryn M|Bramante, Gianni|Baldwin, Graham S|Shulkes, Arthur
PMID: 20727916
Journal: FEBS Lett. 2010 Sep 24;584(18):4077-82.
Title: Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.
Author: Ramachandran, Subramaniam|Shida, Dai|Nagahashi, Masayuki|Fang, Xianjun|Milstien, Sheldon|Takabe, Kazuaki|Spiegel, Sarah
PMID: 20804754
Journal: Oncol Rep. 2010 Oct;24(4):957-63.
Title: Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer.
Author: Lee, Hyunseung|Lee, Ju-Hee|Jung, Kyung Hee|Hong, Soon-Sun
PMID: 20811676
Journal: Expert Rev Anticancer Ther. 2010 Sep;10(9):1375-9.
Title: Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics.
Author: Katoh, Masaru
PMID: 20836672
Journal: Cancer Res. 2010 Oct 15;70(20):7981-91.
Title: Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters.
Author: Mi, Yan-Jun|Liang, Yong-Ju|Huang, Hong-Bing|Zhao, Hong-Yun|Wu, Chung-Pu|Wang, Fang|Tao, Li-Yang|Zhang, Chuan-Zhao|Dai, Chun-Ling|Tiwari, Amit K|Ma, Xiao-Xu|To, Kenneth Kin Wah|Ambudkar, Suresh V|Chen, Zhe-Sheng|Fu, Li-Wu
PMID: 20876799
Journal: Int J Oncol. 2010 Nov;37(5):1345-52.
Title: Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: the role of reactive oxygen species and Akt.
Author: Zhao, Xiao-Chun|Tian, Li|Cao, Jian-Guo|Liu, Fei
PMID: 20878083
Journal: Biomed Pharmacother. 2010 Nov;64(9):600-4.
Title: Blocking of PI3K/AKT induces apoptosis by its effect on NF-kappaB activity in gastric carcinoma cell line SGC7901.
Author: Chao, Xu|Zao, Jiang|Xiao-Yi, Gu|Li-Jun, Meng|Tao, Shi
PMID: 20947290
Journal: World J Gastroenterol. 2010 Oct 21;16(39):4986-91.
Title: Up-regulation of PIK3CA promotes metastasis in gastric carcinoma.
Author: Liu, Ji-Fang|Zhou, Xin-Ke|Chen, Jin-Hui|Yi, Gao|Chen, He-Ge|Ba, Ming-Chen|Lin, Sheng-Qu|Qi, Yan-Chao
PMID: 20954287
Journal: Am J Pathol. 2010 Dec;177(6):2701-7.
Title: Dopamine, by acting through its D2 receptor, inhibits insulin-like growth factor-I (IGF-I)-induced gastric cancer cell proliferation via up-regulation of Kruppel-like factor 4 through down-regulation of IGF-IR and AKT phosphorylation.
Author: Ganguly, Subhalakshmi|Basu, Biswarup|Shome, Saurav|Jadhav, Tushar|Roy, Sudipta|Majumdar, Jahar|Dasgupta, Partha Sarathi|Basu, Sujit
PMID: 21075859
Journal: PPAR Res. 2010;2010:571783.
Title: Induction of metastatic gastric cancer by peroxisome proliferator-activated receptordelta activation.
Author: Pollock, Claire B|Rodriguez, Olga|Martin, Philip L|Albanese, Chris|Li, Xin|Kopelovich, Levy|Glazer, Robert I
PMID: 21318167
Journal: Mol Med Rep. 2010 May-Jun;3(3):491-6.
Title: Phosphoinositide 3-kinase/Akt and nuclear factor kappaB pathways are involved in tumor necrosis factor-related apoptosis-inducing ligand resistance in human gastric cancer cells.
Author: Liu, Jing|Qu, Xiujuan|Xu, Ling|Zhang, Ye|Qu, Jinglei|Hou, Kezuo|Liu, Yunpeng
PMID: 21472268
Journal: Med Oncol. 2011 Jun;28(2):455-62.
Title: Astrocyte-elevated gene-1 overexpression is associated with poor prognosis in gastric cancer.
Author: Jian-bo, Xu|Hui, Wu|Yu-long, He|Chang-hua, Zhang|Long-juan, Zhang|Shi-rong, Cai|Wen-hua, Zhan
PMID: 20300973
Journal: Dig Dis Sci. 2011 Feb;56(2):323-9.
Title: Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis.
Author: Redlak, Maria J|Miller, Thomas A
PMID: 20585984
Journal: Int J Cancer. 2011 Jul 15;129(2):275-84.
Title: Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer.
Author: Wei, Lingyun|Xu, Zhifei
PMID: 20839260
Journal: Oncogene. 2011 Feb 24;30(8):956-66.
Title: Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells.
Author: Asciutti, S|Akiri, G|Grumolato, L|Vijayakumar, S|Aaronson, S A
PMID: 21042278
Journal: J Pathol. 2011 Feb;223(3):400-9.
Title: BCL2L10 protein regulates apoptosis/proliferation through differential pathways in gastric cancer cells.
Author: Xu, Jing Da|Cao, Xi Xi|Long, Zi Wen|Liu, Xiu Ping|Furuya, Tomoko|Xu, Jia Wen|Liu, Xiao Li|De Xu, Zu|Sasaki, Kohsuke|Li, Qing Quan
PMID: 21171085
Journal: World J Gastroenterol. 2011 Jan 14;17(2):181-90.
Title: LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway.
Author: Liu, Jie|Fu, Xue-Qiong|Zhou, Wei|Yu, Hong-Gang|Yu, Jie-Ping|Luo, He-Sheng
PMID: 21245990
Journal: Cancer. 2011 Jul 15;117(14):3135-47.
Title: Insulin-like growth factor-I receptor blockade reduces tumor angiogenesis and enhances the effects of bevacizumab for a human gastric cancer cell line, MKN45.
Author: Li, Hua|Adachi, Yasushi|Yamamoto, Hiroyuki|Min, Yongfen|Ohashi, Hirokazu|Ii, Masanori|Arimura, Yoshiaki|Endo, Takao|Lee, Choon-Taek|Carbone, David P|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 21264842
Journal: Cancer Res. 2011 Feb 1;71(3):1081-91.
Title: Multiple mutations and bypass mechanisms can contribute to development of acquired resistance to MET inhibitors.
Author: Qi, Jie|McTigue, Michele A|Rogers, Andrew|Lifshits, Eugene|Christensen, James G|Janne, Pasi A|Engelman, Jeffrey A
PMID: 21266357
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: Mol Nutr Food Res. 2011 May;55(5):749-60.
Title: Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells.
Author: Xing, Xin|Wang, Juan|Xing, Ling Xiao|Li, Yue Hong|Yan, Xia|Zhang, Xiang Hong
PMID: 21287681
Journal: PLoS One. 2011 Feb 18;6(2):e16694.
Title: A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.
Author: Kim, Hark Kyun|Choi, Il Ju|Kim, Chan Gyoo|Kim, Hee Sung|Oshima, Akira|Michalowski, Aleksandra|Green, Jeffrey E
PMID: 21364753
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Feb;14(2):140-2.
Title: [Expression and clinical significance of epidermal growth factor receptor and protein kinase B in gastric carcinoma].
Author: Zhang, Hong-Yu|Tao, Hong-Mei|Chen, Hong-Tao
PMID: 21365510
Journal: BMC Cancer. 2011 Mar 27;11:109.
Title: P27(Kip1), regulated by glycogen synthase kinase-3beta, results in HMBA-induced differentiation of human gastric cancer cells.
Author: Wei, Min|Wang, Zhiwei|Yao, Hongliang|Yang, Zhongyin|Zhang, Qing|Liu, Bingya|Yu, Yingyan|Su, Liping|Zhu, Zhenggang|Gu, Qinlong
PMID: 21439087
Journal: Cancer Sci. 2011 Jul;102(7):1388-95.
Title: Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins.
Author: Lee, Kyung-Hun|Lee, Ju-Hee|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue
PMID: 21453385
Journal: Gastric Cancer. 2011 Oct;14(4):339-52.
Title: A small interfering RNA targeting the KLF6 splice variant, KLF6-SV1, as gene therapy for gastric cancer.
Author: Chen, Hui|Chen, Lili|Sun, Lingyu|Zhen, Hongqun|Li, Xiaomei|Zhang, Qifan
PMID: 21538018
Journal: Exp Cell Res. 2011 Jul 15;317(12):1746-62.
Title: Metastatic function of BMP-2 in gastric cancer cells: the role of PI3K/AKT, MAPK, the NF-kappaB pathway, and MMP-9 expression.
Author: Kang, Myoung Hee|Oh, Sang Cheul|Lee, Hyun Joo|Kang, Han Na|Kim, Jung Lim|Kim, Jun Suk|Yoo, Young A
PMID: 21570392
Journal: BMC Cancer. 2011 May 20;11:183.
Title: beta-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis.
Author: Liu, Jing|Zhang, Ye|Qu, Jinglei|Xu, Ling|Hou, Kezuo|Zhang, Jingdong|Qu, Xiujuan|Liu, Yunpeng
PMID: 21595977
Journal: Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1.
Title: Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling.
Author: Wang, Kui|Liu, Rui|Li, Jingyi|Mao, Jiali|Lei, Yunlong|Wu, Jinhua|Zeng, Jun|Zhang, Tao|Wu, Hong|Chen, Lijuan|Huang, Canhua|Wei, Yuquan
PMID: 21610320
Journal: Clin Cancer Res. 2011 Aug 15;17(16):5322-32.
Title: Gastric cancer growth control by BEZ235 in vivo does not correlate with PI3K/mTOR target inhibition but with [18F]FLT uptake.
Author: Fuereder, Thorsten|Wanek, Thomas|Pflegerl, Pamina|Jaeger-Lansky, Agnes|Hoeflmayer, Doris|Strommer, Sabine|Kuntner, Claudia|Wrba, Friedrich|Werzowa, Johannes|Hejna, Michael|Muller, Markus|Langer, Oliver|Wacheck, Volker
PMID: 21712451
Journal: Chin J Cancer. 2011 Jul;30(7):490-6.
Title: Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells.
Author: Xu, Ling|Qu, Xiu-Juan|Liu, Yun-Peng|Xu, Ying-Ying|Liu, Jing|Hou, Ke-Zuo|Zhang, Ye
PMID: 21718595
Journal: Gastroenterology. 2011 Nov;141(5):1738-48.e1-2.
Title: DARPP-32 increases interactions between epidermal growth factor receptor and ERBB3 to promote tumor resistance to gefitinib.
Author: Zhu, Shoumin|Belkhiri, Abbes|El-Rifai, Wael
PMID: 21741919
Journal: Mol Med Rep. 2011 Nov-Dec;4(6):1163-7.
Title: Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway.
Author: Sang, Jianrong|Chen, Yongchang|Tao, Yan
PMID: 21769431
Journal: Apoptosis. 2011 Oct;16(10):1028-41.
Title: Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.
Author: Kannaiyan, Radhamani|Manu, Kanjoormana Aryan|Chen, Luxi|Li, Feng|Rajendran, Peramaiyan|Subramaniam, Aruljothi|Lam, Paula|Kumar, Alan Prem|Sethi, Gautam
PMID: 21786165
Journal: Cancer Lett. 2011 Nov 28;310(2):170-80.
Title: The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway.
Author: Sun, Ping Hu|Zhu, Li Ming|Qiao, Min Min|Zhang, Yong Ping|Jiang, Shi Hu|Wu, Yun Lin|Tu, Shui Ping
PMID: 21788101
Journal: J Pathol. 2011 Nov;225(3):438-47.
Title: Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop.
Author: Wu, Yan|Zhao, Qiyi|Peng, Chen|Sun, Lin|Li, Xue-Feng|Kuang, Dong-Ming
PMID: 21826665
Journal: J Cancer Res Clin Oncol. 2011 Nov;137(11):1697-704.
Title: Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers.
Author: Yoon, Jung Hwan|Kang, Young Hwi|Choi, Yoo Jin|Park, In Soo|Nam, Suk Woo|Lee, Jung Young|Lee, Yun Sil|Park, Won Sang
PMID: 21898090
Journal: J Exp Clin Cancer Res. 2011 Sep 25;30:86.
Title: Aquaporin-3 positively regulates matrix metalloproteinases via PI3K/AKT signal pathway in human gastric carcinoma SGC7901 cells.
Author: Xu, Hao|Xu, Yong|Zhang, Wenjie|Shen, Lizong|Yang, Li|Xu, Zekuan
PMID: 21943213
Journal: Med Hypotheses. 2011 Dec;77(6):948-52.
Title: Co-expression of erythropoietin receptor with human epidermal growth factor 2 may counteract trastuzumab inhibition in gastric cancer.
Author: Li, Rui|Yuan, Lingyan|Wang, Jin|Wang, Jiejun
PMID: 21944379
Journal: Cancer Res. 2011 Nov 15;71(22):7061-70.
Title: Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer.
Author: Yoo, Young A|Kang, Myoung Hee|Lee, Hyun Joo|Kim, Baek-hui|Park, Jong Kuk|Kim, Hyun Koo|Kim, Jun Suk|Oh, Sang Cheul
PMID: 21975935
Journal: World J Gastroenterol. 2011 Aug 28;17(32):3700-8.
Title: RNAi knockdown of PIK3CA preferentially inhibits invasion of mutant PIK3CA cells.
Author: Zhou, Xin-Ke|Tang, Sheng-Song|Yi, Gao|Hou, Min|Chen, Jin-Hui|Yang, Bo|Liu, Ji-Fang|He, Zhi-Min
PMID: 21990951
Journal: Virchows Arch. 2011 Nov;459(5):465-75.
Title: Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update.
Author: Morra, Laura|Moch, Holger
PMID: 21997759
Journal: BMC Cancer. 2011 Dec 7;11:509.
Title: Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
Author: Luber, Birgit|Deplazes, Joelle|Keller, Gisela|Walch, Axel|Rauser, Sandra|Eichmann, Martin|Langer, Rupert|Hofler, Heinz|Hegewisch-Becker, Susanna|Folprecht, Gunnar|Woll, Ewald|Decker, Thomas|Endlicher, Esther|Lorenzen, Sylvie|Fend, Falko|Peschel, Christian
PMID: 22152101
Journal: Anticancer Res. 2011 Dec;31(12):4387-92.
Title: Targeting AKT protein kinase in gastric cancer.
Author: Almhanna, Khaldoun|Strosberg, Jonathan|Malafa, Mokenge
PMID: 22199303
Journal: Med Oncol. 2012 Jun;29(2):948-56.
Title: PTP1B expression contributes to gastric cancer progression.
Author: Wang, Jinguo|Liu, Bingya|Chen, Xuehua|Su, Liping|Wu, Pei|Wu, Jian|Zhu, Zhenggang
PMID: 21442314
Journal: Oncogene. 2012 Mar 15;31(11):1398-407.
Title: MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1.
Author: Xu, Y|Zhao, F|Wang, Z|Song, Y|Luo, Y|Zhang, X|Jiang, L|Sun, Z|Miao, Z|Xu, H
PMID: 21822301
Journal: Oncogene. 2012 Apr 5;31(14):1771-80.
Title: Promotion of cytoplasmic mislocalization of p27 by Helicobacter pylori in gastric cancer.
Author: Wen, S|So, Y|Singh, K|Slingerland, J M|Resnick, M B|Zhang, S|Ruiz, V|Moss, S F
PMID: 21841827
Journal: Cancer Sci. 2012 Feb;103(2):342-9.
Title: Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.
Author: Ono, Naomi|Yamazaki, Toshikazu|Nakanishi, Yoshito|Fujii, Toshihiko|Sakata, Kiyoaki|Tachibana, Yukako|Suda, Atsushi|Hada, Kihito|Miura, Takaaki|Sato, Shigeo|Saitoh, Ryoichi|Nakano, Kohnosuke|Tsukuda, Takuo|Mio, Toshiyuki|Ishii, Nobuya|Kondoh, Osamu|Aoki, Y
PMID: 22050138
Journal: Surg Today. 2012 Apr;42(4):313-27.
Title: Molecular targeted agents for gastric and gastroesophageal junction cancer.
Author: Oshima, Takashi|Masuda, Munetaka
PMID: 22127535
Journal: Mol Cancer Ther. 2012 Feb;11(2):439-51.
Title: Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.
Author: Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22135232
Journal: Int J Oncol. 2012 Apr;40(4):1153-61.
Title: Magnolol, a natural compound, induces apoptosis of SGC-7901 human gastric adenocarcinoma cells via the mitochondrial and PI3K/Akt signaling pathways.
Author: Rasul, Azhar|Yu, Bo|Khan, Muhammad|Zhang, Kun|Iqbal, Furhan|Ma, Tonghui|Yang, Hong
PMID: 22139054
Journal: Int J Oncol. 2012 Apr;40(4):975-82.
Title: Antitumor effect of cetuximab in combination with S-1 in EGFR-amplified gastric cancer cells.
Author: Fukuda, Kazumasa|Saikawa, Yoshiro|Takahashi, Masashi|Takahashi, Tsunehiro|Wada, Norihito|Kawakubo, Hirohumi|Takeuchi, Hiroya|Kitagawa, Yuko
PMID: 22139134
Journal: Mol Nutr Food Res. 2012 Feb;56(2):325-35.
Title: Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion.
Author: Rubach, Malte|Lang, Roman|Seebach, Elisabeth|Somoza, Mark M|Hofmann, Thomas|Somoza, Veronika
PMID: 22147653
Journal: Int J Oncol. 2012 Apr;40(4):1259-66.
Title: NVP-BKM120, a novel PI3K inhibitor, shows synergism with a STAT3 inhibitor in human gastric cancer cells harboring KRAS mutations.
Author: Park, Eunju|Park, Jinah|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22159814
Journal: Mol Pharm. 2012 Feb 6;9(2):222-9.
Title: Paclitaxel/tetrandrine coloaded nanoparticles effectively promote the apoptosis of gastric cancer cells based on "oxidation therapy".
Author: Li, Xiaolin|Lu, Xiaowei|Xu, Huae|Zhu, Zhenshu|Yin, Haitao|Qian, Xiaoping|Li, Rutian|Jiang, Xiqun|Liu, Baorui
PMID: 22171565
Journal: Oncogene. 2012 Sep 27;31(39):4302-16.
Title: RUNX3-mediated transcriptional inhibition of Akt suppresses tumorigenesis of human gastric cancer cells.
Author: Lin, F-C|Liu, Y-P|Lai, C-H|Shan, Y-S|Cheng, H-C|Hsu, P-I|Lee, C-H|Lee, Y-C|Wang, H-Y|Wang, C-H|Cheng, J Q|Hsiao, M|Lu, P-J
PMID: 22231444
Journal: Mol Cancer Ther. 2012 Mar;11(3):660-9.
Title: MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells.
Author: Chen, Chin-Tung|Kim, Hyaehwan|Liska, David|Gao, Sizhi|Christensen, James G|Weiser, Martin R
PMID: 22238368
Journal: Pathol Int. 2012 Feb;62(2):127-36.
Title: RON is associated with tumor progression via the inhibition of apoptosis and cell cycle arrest in human gastric cancer.
Author: Song, Young-A|Park, Young-Lan|Kim, Kyu-Yeol|Myung, Eun|Chung, Cho-Yun|Cho, Sung-Bum|Lee, Wan-Sik|Jung, Young-Do|Kweon, Sun-Seog|Joo, Young-Eun
PMID: 22243783
Journal: Mol Med Rep. 2012 Apr;5(4):1075-9.
Title: Downregulation of Id1 by small interfering RNA in gastric cancer inhibits cell growth via the Akt pathway.
Author: Yang, Guang|Zhang, Yan|Xiong, Jianjun|Wu, Jing|Yang, Changfu|Huang, Hongbing|Zhu, Zhenyu
PMID: 22245935
Journal: Oncol Rep. 2012 May;27(5):1511-9.
Title: Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo.
Author: Zhang, Jing|Zhu, Jin-Shui|Zhou, Zhou|Chen, Wei-Xiong|Chen, Ni-Wei
PMID: 22246223
Journal: BMC Cancer. 2012 Feb 1;12:50.
Title: Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer.
Author: Shi, Jing|Yao, Demao|Liu, Wei|Wang, Na|Lv, Hongjun|Zhang, Guanjun|Ji, Meiju|Xu, Li|He, Nongyue|Shi, Bingyin|Hou, Peng
PMID: 22292935
Journal: Int J Oncol. 2012 May;40(5):1553-60.
Title: miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer.
Author: Liu, Zhuo|Zhu, Jiaming|Cao, Hong|Ren, Hui|Fang, Xuedong
PMID: 22293682
Journal: Toxicol Lett. 2012 Apr 5;210(1):78-86.
Title: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells.
Author: Hu, Chen|Zou, Mei-Juan|Zhao, Li|Lu, Na|Sun, Ya-Jing|Gou, Shao-Hua|Xi, Tao|Guo, Qing-Long
PMID: 22322152
Journal: Immunobiology. 2012 Sep;217(9):926-34.
Title: Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer.
Author: Tseng, Po-Chun|Huang, Wei-Ching|Chen, Chia-Ling|Sheu, Bor-Shyang|Shan, Yan-Shen|Tsai, Cheng-Chieh|Wang, Chi-Yun|Chen, Su-O|Hsieh, Chia-Yuan|Lin, Chiou-Feng
PMID: 22325465
Journal: Oncologist. 2012;17(3):346-58.
Title: Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?
Author: Wong, Hilda|Yau, Thomas
PMID: 22334453
Journal: J Biol Chem. 2012 Apr 6;287(15):12132-41.
Title: Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
Author: Chen, Guang|Chen, Si-Meng|Wang, Xiang|Ding, Xiao-Fei|Ding, Jian|Meng, Ling-Hua
PMID: 22337890
Journal: PLoS One. 2012;7(2):e31729.
Title: Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.
Author: Liu, Zhi|Xing, Mingzhao
PMID: 22359623
Journal: Regul Pept. 2012 Jun 10;176(1-3):13-21.
Title: RNAi knockdown of the Akt1 gene increases the chemosensitivity of gastric cancer cells to cisplatin both in vitro and in vivo.
Author: Zhou, Wei|Fu, Xue-Qiong|Liu, Jie|Yu, Hong-Gang
PMID: 22387880
Journal: Biochim Biophys Acta. 2012 Jun;1822(6):875-84.
Title: IQGAP2, A candidate tumour suppressor of prostate tumorigenesis.
Author: Xie, Yanyun|Yan, Judy|Cutz, Jean-Claude|Rybak, Adrian P|He, Lizhi|Wei, Fengxiang|Kapoor, Anil|Schmidt, Valentina A|Tao, Lijian|Tang, Damu
PMID: 22406297
Journal: World J Gastroenterol. 2012 Mar 7;18(9):979-85.
Title: Interleukin-8 associates with adhesion, migration, invasion and chemosensitivity of human gastric cancer cells.
Author: Kuai, Wen-Xia|Wang, Qiong|Yang, Xiao-Zhong|Zhao, Yao|Yu, Ren|Tang, Xiao-Jun
PMID: 22408359
Journal: Cell Cycle. 2012 Apr 1;11(7):1414-31.
Title: The roles of REIC gene and its encoding product in gastric carcinoma.
Author: Xu, Xiao-yan|Xia, Pu|Yu, Miao|Nie, Xiao-cui|Yang, Xue|Xing, Ya-nan|Liu, Yun-peng|Takano, Yasuo|Zheng, Hua-chuan
PMID: 22421143
Journal: J Pathol. 2012 Aug;227(4):470-80.
Title: miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1.
Author: Xia, Jintang|Wu, Zhiqiang|Yu, Chunping|He, Weiling|Zheng, Haiqing|He, Yulong|Jian, Weihua|Chen, Lianzhou|Zhang, Luanjing|Li, Wen
PMID: 22450659
Journal: Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15.
Title: Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.
Author: Mueller, Annett|Bachmann, Erika|Linnig, Monika|Khillimberger, Katrin|Schimanski, Carl Christoph|Galle, Peter R|Moehler, Markus
PMID: 22543857
Journal: Tumour Biol. 2012 Oct;33(5):1543-8.
Title: Midkine confers Adriamycin resistance in human gastric cancer cells.
Author: Xu, Ying-ying|Mao, Xiao-yun|Song, Yong-xi|Zhao, Feng|Wang, Zhen-ning|Zhang, Wei-xu|Xu, Hui-mian|Jin, Feng
PMID: 22576950
Journal: Int J Oncol. 2012 Sep;41(3):839-48.
Title: Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting betacatenin signaling.
Author: Kundu, Juthika|Wahab, S M Riajul|Kundu, Joydeb Kumar|Choi, Yoon-La|Erkin, Ozgur Cem|Lee, Hun Seok|Park, Sang Gyu|Shin, Young Kee
PMID: 22710759
Journal: Oncol Rep. 2012 Sep;28(3):1043-50.
Title: Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Author: Shin, Dong Yeok|Kim, Gi-Young|Kim, Chan Gil|Kim, Wun-Jae|Kang, Ho Sung|Choi, Yung Hyun
PMID: 22710922
Journal: Apoptosis. 2012 Oct;17(10):1104-19.
Title: Dracorhodin perchlorate inhibits PI3K/Akt and NF-kappaB activation, up-regulates the expression of p53, and enhances apoptosis.
Author: Rasul, Azhar|Ding, Chuan|Li, Xiaomeng|Khan, Muhammad|Yi, Fei|Ali, Muhammad|Ma, Tonghui
PMID: 22711363
Journal: Mol Cancer Ther. 2012 Jul;11(7):1557-64.
Title: Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification.
Author: Okamoto, Wataru|Okamoto, Isamu|Arao, Tokuzo|Kuwata, Kiyoko|Hatashita, Erina|Yamaguchi, Haruka|Sakai, Kazuko|Yanagihara, Kazuyoshi|Nishio, Kazuto|Nakagawa, Kazuhiko
PMID: 22729845
Journal: Cancer Lett. 2012 Dec 1;325(1):72-9.
Title: A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
Author: Kim, Hye-Lin|Jeon, Kyung-Hwa|Jun, Kyu-Yeon|Choi, Yongmun|Kim, Dae-Kee|Na, Younghwa|Kwon, Youngjoo
PMID: 22732416
Journal: BMC Cancer. 2012 Jul 16;12:290.
Title: ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI(3)K and MAPK signaling pathways in gastric cancer.
Author: Zhong, Jing|Chen, Shujie|Xue, Meng|Du, Qin|Cai, Jianting|Jin, Hongchuan|Si, Jianmin|Wang, Liangjing
PMID: 22799764
Journal: Cancer Lett. 2012 Dec 29;326(1):105-13.
Title: Global gene expression and functional network analysis of gastric cancer identify extended pathway maps and GPRC5A as a potential biomarker.
Author: Cheng, Lei|Yang, Sheng|Yang, Yanqing|Zhang, Wen|Xiao, Huasheng|Gao, Hengjun|Deng, Xiaxing|Zhang, Qinghua
PMID: 22867946
Journal: J Dig Dis. 2012 Sep;13(9):453-8.
Title: The proliferative effects of ghrelin on human gastric cancer AGS cells.
Author: Tian, Pei Ying|Fan, Xiao Ming
PMID: 22908970
Journal: World J Gastroenterol. 2012 Aug 14;18(30):3923-30.
Title: Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers.
Author: Cao, Dong-Xing|Li, Zhi-Jie|Jiang, Xiao-Ou|Lum, Yick Liang|Khin, Ester|Lee, Nikki P|Wu, Guo-Hao|Luk, John M
PMID: 22912540
Journal: Mol Med Rep. 2012 Nov;6(5):1030-4.
Title: Adrenomedullin is involved in the progression of colonic adenocarcinoma.
Author: Kim, Jee-Youn|Park, Won-Do|Lee, Sun|Park, Jae-Hoon
PMID: 22923200
Journal: PLoS One. 2012;7(9):e44615.
Title: Revealing the molecular mechanism of gastric cancer marker annexin A4 in cancer cell proliferation using exon arrays.
Author: Lin, Li-Ling|Huang, Hsuan-Cheng|Juan, Hsueh-Fen
PMID: 22970268
Journal: Mol Nutr Food Res. 2012 Nov;56(11):1617-26.
Title: Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort.
Author: Yang, Jae Jeong|Cho, Lisa Y|Ko, Kwang-Pil|Ma, Seung Hyun|Shin, Aesun|Choi, Bo Youl|Han, Dong Soo|Song, Kyu Sang|Kim, Yong Sung|Chang, Soung-Hoon|Shin, Hai-Rim|Kang, Daehee|Yoo, Keun-Young|Park, Sue K
PMID: 23042672
Journal: Int J Immunopathol Pharmacol. 2012 Jul-Sep;25(3):627-36.
Title: Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Author: Ye, B|Jiang, L-L|Xu, H-T|Zhou, D-W|Li, Z-S
PMID: 23058013
Journal: PLoS One. 2012;7(11):e47545.
Title: Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.
Author: Naito, Yutaka|Oue, Naohide|Hinoi, Takao|Sakamoto, Naoya|Sentani, Kazuhiro|Ohdan, Hideki|Yanagihara, Kazuyoshi|Sasaki, Hiroki|Yasui, Wataru
PMID: 23133598
Journal: Mol Cells. 2012 Dec;34(6):523-9.
Title: A new anti-c-Met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer.
Author: Oh, Young Mi|Song, Yun-Jeong|Lee, Saet Byoul|Jeong, Yunju|Kim, Bogyou|Kim, Geun Woong|Kim, Kyung Eun|Lee, Ji Min|Cho, Mi-Young|Choi, Jaehyun|Nam, Do-Hyun|Song, Paul H|Cheong, Kwang Ho|Kim, Kyung-Ah
PMID: 23180291
Journal: Oncol Lett. 2012 Dec;4(6):1213-1218.
Title: Immunohistochemical expression of mTOR negatively correlates with PTEN expression in gastric carcinoma.
Author: Li, Min|Sun, Huawen|Song, Lujun|Gao, Xiaodong|Chang, Wenju|Qin, Xinyu
PMID: 23205120
Journal: World J Gastroenterol. 2012 Dec 7;18(45):6577-86.
Title: Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer.
Author: Sukawa, Yasutaka|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Kunimoto, Hiroaki|Suzuki, Hiromu|Adachi, Yasushi|Nakazawa, Mayumi|Nobuoka, Takayuki|Kawayama, Mariko|Mikami, Masashi|Matsuno, Takashi|Hasegawa, Tadashi|Hirata, Koichi|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 23236232
Journal: Cell Host Microbe. 2012 Dec 13;12(6):764-77.
Title: Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells.
Author: Tsugawa, Hitoshi|Suzuki, Hidekazu|Saya, Hideyuki|Hatakeyama, Masanori|Hirayama, Toshiya|Hirata, Kenro|Nagano, Osamu|Matsuzaki, Juntaro|Hibi, Toshifumi
PMID: 23245321
Journal: PLoS One. 2012;7(12):e50811.
Title: Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner.
Author: Yang, Yong|Li, Xian-Jing|Chen, Zhen|Zhu, Xuan-Xuan|Wang, Jing|Zhang, Lin-bo|Qiang, Lei|Ma, Yan-Jun|Li, Zhi-yu|Guo, Qing-Long|You, Qi-Dong
PMID: 23251389
Journal: Asian Pac J Cancer Prev. 2012;13(11):5339-43.
Title: Anti-tumor activity and apoptosis-regulation mechanisms of bufalin in various cancers: new hope for cancer patients.
Author: Yin, Pei-Hao|Liu, Xuan|Qiu, Yan-Yan|Cai, Jian-feng|Qin, Jian-min|Zhu, Hui-Rong|Li, Qi
PMID: 23317181
Journal: Asian Pac J Cancer Prev. 2012;13(11):5619-25.
Title: Role of integrin-linked kinase in multi-drug resistance of human gastric carcinoma SGC7901/DDP cells.
Author: Song, Wei|Jiang, Rui|Zhao, Chun-Ming
PMID: 23317227
Journal: World J Gastroenterol. 2012 Dec 28;18(48):7262-70.
Title: Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45.
Author: Guo, Ling-Yun|Li, Yu-Min|Qiao, Liang|Liu, Tao|Du, Yuan-Yuan|Zhang, Jun-Qiang|He, Wen-Ting|Zhao, Yong-Xun|He, Dong-Qiang
PMID: 23326131
Journal: J Ginseng Res. 2012 Apr;36(2):135-45.
Title: Inhibition of Hydrogen Sulfide-induced Angiogenesis and Inflammation in Vascular Endothelial Cells: Potential Mechanisms of Gastric Cancer Prevention by Korean Red Ginseng.
Author: Choi, Ki-Seok|Song, Heup|Kim, Eun-Hee|Choi, Jae Hyung|Hong, Hua|Han, Young-Min|Hahm, Ki Baik
PMID: 23717113
Journal: World J Virol. 2012 Dec 12;1(6):154-61.
Title: Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications.
Author: Chen, Jiezhong
PMID: 24175221
Journal: Integr Cancer Ther. 2013 Mar;12(2):165-73.
Title: Lactobacillus casei extract induces apoptosis in gastric cancer by inhibiting NF-kappaB and mTOR-mediated signaling.
Author: Hwang, Jeong Won|Baek, Young-Mi|Yang, Kyeong Eun|Yoo, Hwa-Seung|Cho, Chong-Kwan|Lee, Yeon-Weol|Park, Junsoo|Eom, Chi-Yong|Lee, Zee-Won|Choi, Jong-Soon|Jang, Ik-Soon
PMID: 22505595
Journal: Gut. 2013 Oct;62(10):1415-24.
Title: A systematic approach to therapeutic target selection in oesophago-gastric cancer.
Author: Paterson, Anna L|Shannon, Nicholas B|Lao-Sirieix, Pierre|Ong, Chin-Ann J|Peters, Christopher J|O'Donovan, Maria|Fitzgerald, Rebecca C
PMID: 22773546
Journal: Oncogene. 2013 Jul 11;32(28):3319-28.
Title: ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.
Author: Du, W|Wang, S|Zhou, Q|Li, X|Chu, J|Chang, Z|Tao, Q|Ng, E K O|Fang, J|Sung, J J Y|Yu, J
PMID: 22907434
Journal: Mol Biol Rep. 2013 Feb;40(2):1677-83.
Title: Upregulation of periostin prevents P53-mediated apoptosis in SGC-7901 gastric cancer cells.
Author: Li, Bin|Wang, Liyan|Chi, Baorong
PMID: 23076534
Journal: Arch Toxicol. 2013 Mar;87(3):481-90.
Title: Apoptosis initiation of beta-ionone in SGC-7901 gastric carcinoma cancer cells via a PI3K-AKT pathway.
Author: Liu, Qian|Dong, Hong-Wei|Sun, Wen-Guang|Liu, Ming|Ibla, Juan C|Liu, Lian-Xin|Parry, John W|Han, Xiao-Hui|Li, Ming-Song|Liu, Jia-Ren
PMID: 23100158
Journal: Mol Biol Rep. 2013 Feb;40(2):999-1008.
Title: Effect of PI3K gene silencing on growth, migration and related proteins expression of CD40 signal-mediated gastric cancer cells.
Author: Li, Rui|Chen, Wei-Chang|Pang, Xue-Qin|Tian, Wen-Yan|Wang, Wei-Peng|Zhang, Xue Guang
PMID: 23114914
Journal: Cell Signal. 2013 Feb;25(2):447-56.
Title: PI3K/Akt-dependent phosphorylation of GSK3beta and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration.
Author: Liu, Jiaojing|Zhang, Yujie|Xu, Rui|Du, Jun|Hu, Zhenzhen|Yang, Ling|Chen, Yongchang|Zhu, Yichao|Gu, Luo
PMID: 23123500
Journal: Toxicol Appl Pharmacol. 2013 Jan 1;266(1):76-85.
Title: Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-kappaB activity.
Author: Ho, Hsieh-Hsun|Chang, Chi-Sen|Ho, Wei-Chi|Liao, Sheng-You|Lin, Wea-Lung|Wang, Chau-Jong
PMID: 23153558
Journal: Oncol Rep. 2013 Feb;29(2):535-40.
Title: Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance.
Author: Li, Ang|Lu, Dehong|Zhang, Yupeng|Li, Jia|Fang, Yu|Li, Fei|Sun, Jiabang
PMID: 23165320
Journal: Cell Oncol (Dordr). 2013 Apr;36(2):141-53.
Title: CD81 is a candidate tumor suppressor gene in human gastric cancer.
Author: Yoo, Tae-Hyoung|Ryu, Byung-Kyu|Lee, Min-Goo|Chi, Sung-Gil
PMID: 23264205
Journal: Tumour Biol. 2013 Apr;34(2):875-85.
Title: Inhibitory effects of eupatilin on tumor invasion of human gastric cancer MKN-1 cells.
Author: Park, Byeong Bae|Yoon, Jin sun|Kim, Eun shil|Choi, Jiyoung|Won, Young woong|Choi, Jung hye|Lee, Young Yiul
PMID: 23292941
Journal: Hepatogastroenterology. 2013 Jun;60(124):943-8.
Title: Tumor-suppressive effects of 1, 25-dihydroxyvitamin D3 in gastric cancer cells.
Author: Bao, Anyu|Li, Yan|Tong, Yongqing|Zheng, Hongyun|Wu, Wei|Wei, Chuandong
PMID: 23298900
Journal: Cancer Lett. 2013 May 10;332(1):74-82.
Title: KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.
Author: Hong, Sang-Won|Jung, Kyung-Hee|Park, Byung Hee|Zheng, Hong-Mei|Lee, Hee-Seung|Choi, Myung-Joo|Yun, Jeong In|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun
PMID: 23348694
Journal: Carcinogenesis. 2013 May;34(5):974-83.
Title: Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.
Author: Dong, Zhaogang|Xu, Xiaofei|Du, Lutao|Yang, Yongmei|Cheng, Huanhuan|Zhang, Xin|Li, Zewu|Wang, Lili|Li, Juan|Liu, Hui|Qu, Xun|Wang, Chuanxin
PMID: 23354307
Journal: Cancer Lett. 2013 May 10;332(1):11-8.
Title: Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells.
Author: Xu, Wei|Chen, Guo-Sheng|Shao, Yun|Li, Xiao-Lin|Xu, Hai-Chen|Zhang, Hao|Zhu, Guo-Qing|Zhou, Yi-Chan|He, Xiao-Pu|Sun, Wei-Hao
PMID: 23376640
Journal: Int J Oncol. 2013 Apr;42(4):1417-26.
Title: Protective role of autophagy in matrineinduced gastric cancer cell death.
Author: Li, Yumin|Zhang, Junqiang|Ma, Haizhen|Chen, Xiaohui|Liu, Tao|Jiao, Zuoyi|He, Wenting|Wang, Furong|Liu, Xiaokang|Zeng, Xiangting
PMID: 23404079
Journal: Biochem Pharmacol. 2013 May 1;85(9):1246-56.
Title: Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.
Author: Lu, Chunwan|Liu, Di|Jin, Jing|Deokar, Hemantkumar|Zhang, Yi|Buolamwini, John K|Yu, Xiaoming|Yan, Chunhong|Chen, Xiaoguang
PMID: 23415900
Journal: Oncol Lett. 2013 Feb;5(2):574-582.
Title: Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Author: Wang, Jun Pu|Hu, Wan Ming|Wang, Kuan Song|Yu, Jun|Luo, Bai Hua|Wu, Chang|Chen, Zhi Hong|Luo, Geng Qiu|Liu, Yu Wu|Liu, Qin Lai|Xiao, Yan|Zhou, Hai Yan|Yang, Xiao Jing|Jiang, Hai Ying|Li, Jing He|Wen, Ji Fang
PMID: 23420470
Journal: Onkologie. 2013;36(1-2):26-31.
Title: Markers CD40, VEGF, AKT, PI3K, and S100 correlate with tumor stage in gastric cancer.
Author: Tian, Wen-Yan|Chen, Wei-Chang|Li, Rui|Liu, Lei
PMID: 23429328
Journal: Cancer Cell Int. 2013 Feb 21;13(1):18.
Title: Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer.
Author: Xie, Biao|Zhou, Jianping|Shu, Guoshun|Liu, Dong-Cai|Zhou, Jiapeng|Chen, Jinhui|Yuan, Lianwen
PMID: 23432957
Journal: Mol Biol Rep. 2013 Apr;40(4):2947-53.
Title: SGT1 regulates Akt signaling by promoting beta-TrCP-dependent PHLPP1 degradation in gastric cancer cells.
Author: Gao, Ganglong|Kun, Tao|Sheng, Youhua|Qian, Min|Kong, Fanzhi|Liu, Xiaoguang|Yu, Zhenfeng|Zhang, Haiqin|Zhang, Qiang|Gu, Jianping|Zhang, Xueli
PMID: 23440515
Journal: Mol Cancer Ther. 2013 May;12(5):737-46.
Title: Y-box binding protein-1 contributes to both HER2/ErbB2 expression and lapatinib sensitivity in human gastric cancer cells.
Author: Shibata, Tomohiro|Kan, Hitoshi|Murakami, Yuichi|Ureshino, Hiroki|Watari, Kosuke|Kawahara, Akihiko|Kage, Masayoshi|Hattori, Satoshi|Ono, Mayumi|Kuwano, Michihiko
PMID: 23445612
Journal: Toxicology. 2013 Apr 5;306:162-8.
Title: miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN.
Author: Yang, Shou-Mei|Huang, Cheng|Li, Xiao-Feng|Yu, Ming-Zhe|He, Yong|Li, Jun
PMID: 23466500
Journal: World J Gastroenterol. 2013 Feb 28;19(8):1239-46.
Title: Effect of silencing of high mobility group A2 gene on gastric cancer MKN-45 cells.
Author: Wei, Chun-Hui|Wei, Li-Xiu|Lai, Ming-Yu|Chen, Jia-Zhuang|Mo, Xi-Jing
PMID: 23482887
Journal: Mol Med Rep. 2013 May;7(5):1387-90.
Title: Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo.
Author: Zhang, Ling-Li|Zhang, Jun|Shen, Lei|Xu, Xi-Ming|Yu, Hong-Gang
PMID: 23546174
Journal: Int J Oncol. 2013 May;42(5):1682-91.
Title: PTEN expression and suppression of proliferation are associated with Cdx2 overexpression in gastric cancer cells.
Author: Bai, Zhi-Gang|Ye, Ying-Jiang|Shen, Dan-Hua|Lu, You-Yong|Zhang, Zhong-Tao|Wang, Shan
PMID: 23546539
Journal: PLoS One. 2013;8(3):e60080.
Title: A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.
Author: Xu, Ming|Tao, Guoquan|Kang, Meiyun|Gao, Yan|Zhu, Haixia|Gong, Weida|Wang, Meilin|Wu, Dongmei|Zhang, Zhengdong|Zhao, Qinghong
PMID: 23555892
Journal: Braz J Med Biol Res. 2013 Apr;46(4):394-404. Epub 2013 Apr 5.
Title: AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells.
Author: Tao, Yurong|Guo, Yan|Liu, Wenchao|Zhang, Jian|Li, Xia|Shen, Lan|Ru, Yi|Xue, Yan|Zheng, Jin|Liu, Xinping|Zhang, Jing|Yao, Libo
PMID: 23558861
Journal: Toxicol Appl Pharmacol. 2013 Jun 15;269(3):205-14.
Title: EGFR tyrosine kinase inhibitory peptide attenuates Helicobacter pylori-mediated hyper-proliferation in AGS enteric epithelial cells.
Author: Himaya, S W A|Dewapriya, Pradeep|Kim, Se-Kwon
PMID: 23566958
Journal: Oncol Rep. 2013 Jun;29(6):2422-30.
Title: Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth.
Author: Liang, Song|Guo, Renhua|Zhang, Zhihong|Liu, Dongxiao|Xu, Hao|Xu, Zekuan|Wang, Xuerong|Yang, Li
PMID: 23588929
Journal: Biochem Biophys Res Commun. 2013 May 10;434(3):688-94.
Title: MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN.
Author: Wang, Fang|Li, Ting|Zhang, Bin|Li, Hong|Wu, Qiong|Yang, Li|Nie, Yongzhan|Wu, Kaichun|Shi, Yongquan|Fan, Daiming
PMID: 23603256
Journal: Onco Targets Ther. 2013 Apr 16;6:403-9.
Title: Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21).
Author: Amini, Afshin|Ehteda, Anahid|Masoumi Moghaddam, Samar|Akhter, Javed|Pillai, Krishna|Morris, David Lawson
PMID: 23620673
Journal: Int Immunopharmacol. 2013 Jun;16(2):332-40.
Title: The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells.
Author: Wu, Xiao-Ting|Liu, Jun-Quan|Lu, Xiao-Ting|Chen, Fu-Xing|Zhou, Zhong-Hai|Wang, Tao|Zhu, Sheng-Ping|Fei, Su-Juan
PMID: 23639256
Journal: Dig Dis Sci. 2013 Aug;58(8):2197-204.
Title: Semaphorin 5A promotes gastric cancer invasion/metastasis via urokinase-type plasminogen activator/phosphoinositide 3-kinase/protein kinase B.
Author: Pan, Guoqing|Zhu, Zhu|Huang, Jian|Yang, Chenggang|Yang, Ying|Wang, Yingxia|Tuo, Xiaoyu|Su, Guomiao|Zhang, Xiangling|Yang, Zhi|Liu, Tao
PMID: 23661031
Journal: Int J Mol Sci. 2013 May 10;14(5):10075-89.
Title: The role of E3 ubiquitin ligase Cbl proteins in beta-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells.
Author: Zhang, Ye|Mu, Xiao-Dong|Li, En-Zhe|Luo, Ying|Song, Na|Qu, Xiu-Juan|Hu, Xue-Jun|Liu, Yun-Peng
PMID: 23665906
Journal: Carcinogenesis. 2013 Sep;34(9):2156-69.
Title: SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities.
Author: Hong, Sang-Won|Jung, Kyung Hee|Lee, Hee-Seung|Son, Mi Kwon|Yan, Hong Hua|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun
PMID: 23671132
Journal: Gastroenterology. 2013 Sep;145(3):554-65.
Title: Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil.
Author: Lei, Zhengdeng|Tan, Iain Beehuat|Das, Kakoli|Deng, Niantao|Zouridis, Hermioni|Pattison, Sharon|Chua, Clarinda|Feng, Zhu|Guan, Yeoh Khay|Ooi, Chia Huey|Ivanova, Tatiana|Zhang, Shenli|Lee, Minghui|Wu, Jeanie|Ngo, Anna|Manesh, Sravanthy|Tan, Elisabeth|Teh, B
PMID: 23684942
Journal: Br J Cancer. 2013 Jun 25;108(12):2557-64.
Title: Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer.
Author: Zhao, J|Liang, Q|Cheung, K-F|Kang, W|Dong, Y|Lung, R W-M|Tong, J H-M|To, K-F|Sung, J J Y|Yu, J
PMID: 23722468
Journal: Oncol Rep. 2013 Aug;30(2):773-82.
Title: Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.
Author: Xie, Xia|Tang, Bo|Zhou, Jianyun|Gao, Qing|Zhang, Pengbing
PMID: 23743572
Journal: Tumori. 2013 Mar-Apr;99(2):249-56.
Title: Integrin-linked kinase silencing induces a S/G2/M phases cell cycle slowing and modulates metastasis-related genes in SGC7901 human gastric carcinoma cells.
Author: Song, Wei|Zhao, Chunming|Jiang, Rui
PMID: 23748822
Journal: Anticancer Res. 2013 Jun;33(6):2541-7.
Title: Cannabinoid receptor agonist as an alternative drug in 5-fluorouracil-resistant gastric cancer cells.
Author: Xian, Xiang-Shu|Park, Hyeyeon|Choi, Myung-Gyu|Park, Jae Myung
PMID: 23749906
Journal: Oncol Rep. 2013 Sep;30(3):1087-93.
Title: Enhanced antitumor activity of trastuzumab emtansine (T-DM1) in combination with pertuzumab in a HER2-positive gastric cancer model.
Author: Yamashita-Kashima, Yoriko|Shu, Sei|Harada, Naoki|Fujimoto-Ouchi, Kaori
PMID: 23783223
Journal: Int J Mol Sci. 2013 Jun 24;14(7):13005-21.
Title: Anti-tumor effects of Mfn2 in gastric cancer.
Author: Zhang, Ge-Er|Jin, Hai-Long|Lin, Xian-Ke|Chen, Chao|Liu, Xiao-Sun|Zhang, Qing|Yu, Ji-Ren
PMID: 23797661
Journal: Carcinogenesis. 2013 Dec;34(12):2861-9.
Title: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
Author: Wu, Jinhua|Xie, Na|Xie, Ke|Zeng, Jun|Cheng, Lin|Lei, Yunlong|Liu, Yuan|Song, Linhong|Dong, Dandan|Chen, Yi|Zeng, Rui|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23803691
Journal: J Hematol Oncol. 2013 Jun 27;6:43.
Title: L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer.
Author: Chen, Dong-liang|Zeng, Zhao-lei|Yang, Jing|Ren, Chao|Wang, De-shen|Wu, Wen-jing|Xu, Rui-hua
PMID: 23806079
Journal: PLoS One. 2013 Jun 27;8(6):e68030.
Title: Bcl-w Enhances Mesenchymal Changes and Invasiveness of Glioblastoma Cells by Inducing Nuclear Accumulation of beta-Catenin.
Author: Lee, Woo Sang|Woo, Eun Young|Kwon, Junhye|Park, Myung-Jin|Lee, Jae-Seon|Han, Young-Hoon|Bae, In Hwa
PMID: 23826359
Journal: Histol Histopathol. 2013 Dec;28(12):1629-38.
Title: Upregulation of GPR34 expression affects the progression and prognosis of human gastric adenocarcinoma by PI3K/PDK1/AKT pathway.
Author: Yu, Weidong|Ma, Shuyun|Wang, Lihong|Zuo, Bo|Li, Mei|Qiao, Zhengguo|Pan, Xiuying|Liu, Yulan|Wang, Jingtong
PMID: 23836308
Journal: Anticancer Res. 2013 Aug;33(8):3295-300.
Title: Increased phosphorylation of AKT in high-risk gastric mucosa.
Author: Sasaki, Takamitsu|Kuniyasu, Hiroki|Luo, Yi|Kitayoshi, Misaho|Tanabe, Eriko|Kato, Daisuke|Shinya, Satoshi|Fujii, Kiyomu|Ohmori, Hitoshi|Yamashita, Yuichi
PMID: 23898095
Journal: Neoplasma. 2013;60(6):605-12.
Title: Overexpression of platelet-derived growth factor-B increases the growth, invasion, and angiogenesis of gastric carcinoma cells through protein kinase B.
Author: Guo, Y|Yin, J|Wang, Z|Zha, L
PMID: 23906294
Journal: Dig Dis Sci. 2013 Oct;58(10):2873-80.
Title: AEG-1 is a target of perifosine and is over-expressed in gastric dysplasia and cancers.
Author: Huang, Wenbin|Yang, Li|Liang, Song|Liu, Dongxiao|Chen, Xi|Ma, Zhuo|Zhai, Sulan|Li, Ping|Wang, Xuerong
PMID: 23912246
Journal: Cancer Biol Ther. 2013 Oct 1;14(10):932-6.
Title: MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines.
Author: Almhanna, Khaldoun|Cubitt, Christopher L|Zhang, Shumin|Kazim, Sabiha|Husain, Kazim|Sullivan, Daniel|Sebti, Said|Malafa, Mokenge
PMID: 23917345
Journal: Cancer Res. 2013 Oct 1;73(19):6013-23.
Title: Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110alpha inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers.
Author: Garrett, Joan T|Sutton, Cammie R|Kurupi, Richard|Bialucha, Carl Uli|Ettenberg, Seth A|Collins, Scott D|Sheng, Qing|Wallweber, Jerry|Defazio-Eli, Lisa|Arteaga, Carlos L
PMID: 23918797
Journal: Eur J Cancer. 2013 Nov;49(17):3752-62.
Title: WD40 repeat-containing 62 overexpression as a novel indicator of poor prognosis for human gastric cancer.
Author: Zeng, Shan|Tao, Yiming|Huang, Jinlin|Zhang, Sai|Shen, Liangfang|Yang, Huixiang|Pei, Haiping|Zhong, Meizuo|Zhang, Gewen|Liu, Ting|Zhou, Ming|Shen, Hong
PMID: 23920402
Journal: Cancer Med. 2013 Jun;2(3):325-33.
Title: Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma.
Author: Werner, Dominique|Atmaca, Akin|Pauligk, Claudia|Pustowka, Anette|Jager, Elke|Al-Batran, Salah-Eddin
PMID: 23930209
Journal: Int J Oncol. 2013 Oct;43(4):1059-65.
Title: Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-beta1 and integrin expression.
Author: Kim, Young-Min|Kim, In-Hye|Nam, Taek-Jeong
PMID: 23934170
Journal: Placenta. 2013 Nov;34(11):1027-35.
Title: The tumor suppressor gastrokine-1 is expressed in placenta and contributes to the regulation of trophoblast migration.
Author: Fahlbusch, F B|Ruebner, M|Huebner, H|Volkert, G|Zuern, C|Thiel, F|Koch, M|Menendez-Castro, C|Wachter, D L|Hartner, A|Rascher, W
PMID: 23993393
Journal: PLoS One. 2013 Aug 29;8(8):e72735.
Title: H. pylori CagL-Y58/E59 prime higher integrin alpha5beta1 in adverse pH condition to enhance hypochlorhydria vicious cycle for gastric carcinogenesis.
Author: Yeh, Yi-Chun|Cheng, Hsiu-Chi|Yang, Hsiao-Bai|Chang, Wei-Lun|Sheu, Bor-Shyang
PMID: 24009701
Journal: Cell Death Dis. 2013 Sep 12;4:e794.
Title: Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production.
Author: Yuan, X|Zhou, Y|Wang, W|Li, J|Xie, G|Zhao, Y|Xu, D|Shen, L
PMID: 24030146
Journal: Int J Oncol. 2013 Nov;43(5):1627-35.
Title: The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer.
Author: Zhang, Chang-Etaua|Awasthi, Niranjan|Schwarz, Margaret A|Schwarz, Roderich E
PMID: 24042258
Journal: Nutr Cancer. 2013;65(7):1034-41.
Title: Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression.
Author: Liu, Yan-Long|Zhang, Guo-Qiang|Yang, Yue|Zhang, Chun-Yan|Fu, Rong-Xia|Yang, Yan-Mei
PMID: 24053672
Journal: Nat Rev Clin Oncol. 2013 Nov;10(11):643-55.
Title: Gastric cancer-molecular and clinical dimensions.
Author: Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A
PMID: 24061039
Journal: Mol Cancer. 2013 Sep 25;12(1):110.
Title: Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells.
Author: Li, He|Wang, Juan|Xu, Huiyu|Xing, Rui|Pan, Yuanming|Li, Wenmei|Cui, Jiantao|Zhang, Hongbing|Lu, Youyong
PMID: 24063558
Journal: Gut Liver. 2013 Sep;7(5):552-9.
Title: The Effect of Helicobacter pylori on Epidermal Growth Factor Receptor-Induced Signal Transduction and the Preventive Effect of Celecoxib in Gastric Cancer Cells.
Author: Kim, Jaeyeon|Kim, Nayoung|Park, Ji Hyun|Chang, Hyun|Kim, Ji Yeon|Lee, Dong Ho|Kim, Jung Mogg|Kim, Joo Sung|Jung, Hyun Chae
PMID: 24073313
Journal: J Transl Med. 2013 Oct 2;11:241.
Title: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere.
Author: Li, Jing|Davies, Barry R|Han, Sufang|Zhou, Minhua|Bai, Yu|Zhang, Jingchuan|Xu, Yan|Tang, Lily|Wang, Huiying|Liu, Yuan Jie|Yin, Xiaolu|Ji, Qunsheng|Yu, De-Hua
PMID: 24088382
Journal: Int J Oncol. 2013 Dec;43(6):2007-14.
Title: Lentivirus-mediated shRNA targeting of cyclin D1 enhances the chemosensitivity of human gastric cancer to 5-fluorouracil.
Author: Seo, Jin-Hee|Jeong, Eui-Suk|Lee, Kyoung-Sun|Heo, Seung-Ho|Jeong, Dong-Gu|Choi, Yang-Kyu
PMID: 24100731
Journal: Acta Biochim Biophys Sin (Shanghai). 2013 Nov;45(11):963-72.
Title: miR-106a confers cisplatin resistance by regulating PTEN/Akt pathway in gastric cancer cells.
Author: Fang, Yue|Shen, Huiling|Li, Hao|Cao, Yuan|Qin, Rong|Long, Lulu|Zhu, Xiaolan|Xie, Chanjuan|Xu, Wenlin
PMID: 24108762
Journal: Cell Death Dis. 2013 Oct 10;4:e847.
Title: The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells.
Author: Zhou, W|Fu, X-Q|Zhang, L-L|Zhang, J|Huang, X|Lu, X-H|Shen, L|Liu, B-N|Liu, J|Luo, H-S|Yu, J-P|Yu, H-G
PMID: 24113181
Journal: Nat Commun. 2013;4:2544.
Title: Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency.
Author: Guo, Shui-Long|Ye, Hui|Teng, Yan|Wang, You-Liang|Yang, Guan|Li, Xiu-Bin|Zhang, Chong|Yang, Xue|Yang, Zhong-Zhou|Yang, Xiao
PMID: 24149576
Journal: J Gastric Cancer. 2013 Sep;13(3):129-35.
Title: Molecular diagnosis for personalized target therapy in gastric cancer.
Author: Cho, Jae Yong
PMID: 24156032
Journal: Cancers (Basel). 2013 Jan 10;5(1):15-26.
Title: The Critical Impact of HIF-1a on Gastric Cancer Biology.
Author: Kitajima, Yoshihiko|Miyazaki, Kohji
PMID: 24216696
Journal: J Immunol. 2013 Dec 15;191(12):6261-72.
Title: The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Author: Mimura, Kousaku|Shiraishi, Kensuke|Mueller, Anja|Izawa, Shinichiro|Kua, Ley-Fang|So, Jimmy|Yong, Wei-Peng|Fujii, Hideki|Seliger, Barbara|Kiessling, Rolf|Kono, Koji
PMID: 24244023
Journal: Breast Cancer Res. 2013 Nov 19;15(6):R110.
Title: A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors.
Author: Hudis, Clifford|Swanton, Charles|Janjigian, Yelena Y|Lee, Ray|Sutherland, Stephanie|Lehman, Robert|Chandarlapaty, Sarat|Hamilton, Nicola|Gajria, Devika|Knowles, James|Shah, Jigna|Shannon, Keith|Tetteh, Ernestina|Sullivan, Daniel M|Moreno, Carolina|Yan, Li
PMID: 24252402
Journal: PLoS One. 2013 Nov 15;8(11):e81702.
Title: Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways.
Author: Dun, Boying|Sharma, Ashok|Teng, Yong|Liu, Haitao|Purohit, Sharad|Xu, Heng|Zeng, Lingwen|She, Jin-Xiong
PMID: 24260584
Journal: Exp Mol Med. 2013 Nov 22;45:e64.
Title: Phosphoproteomic analysis identifies activated MET-axis PI3K/AKT and MAPK/ERK in lapatinib-resistant cancer cell line.
Author: Lee, Yong Yook|Kim, Hwang-Phill|Kang, Min Jueng|Cho, Byoung-Kyu|Han, Sae-Won|Kim, Tae-You|Yi, Eugene C
PMID: 24263233
Journal: Oncol Lett. 2013 Dec;6(6):1723-1728.
Title: Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells.
Author: Wu, Min|Chen, Yongchang|Jiang, Lu|Li, Yueying|Lan, Ting|Wang, Ying|Qian, Hai
PMID: 24273605
Journal: Infect Agent Cancer. 2013 Dec 13;8(1):49.
Title: Akt inhibitors: mechanism of action and implications for anticancer therapeutics.
Author: Bhutani, Jaikrit|Sheikh, Asfandyar|Niazi, Asfandyar Khan
PMID: 24330834
Journal: Am J Transl Res. 2013 Dec 1;6(1):28-42. eCollection 2013.
Title: Transcriptomic changes induced by mycophenolic acid in gastric cancer cells.
Author: Dun, Boying|Sharma, Ashok|Xu, Heng|Liu, Haitao|Bai, Shan|Zeng, Lingwen|She, Jin-Xiong
PMID: 24349619
Journal: Int J Mol Sci. 2013 Dec 16;14(12):24399-411.
Title: Cbl-b enhances sensitivity to 5-fluorouracil via EGFR- and mitochondria-mediated pathways in gastric cancer cells.
Author: Feng, Dan|Ma, Yanju|Liu, Jing|Xu, Ling|Zhang, Ye|Qu, Jinglei|Liu, Yunpeng|Qu, Xiujuan
PMID: 24351824
Journal: Eur J Histochem. 2013 Nov 18;57(4):e36.
Title: Knockdown of RAGE inhibits growth and invasion of gastric cancer cells.
Author: Xu, X C|Abuduhadeer, X|Zhang, W B|Li, T|Gao, H|Wang, Y H
PMID: 24441189
Journal: Gastroenterol Hepatol Bed Bench. 2013 Summer;6(3):146-51.
Title: Study on association between H-ras gene polymorphism and gastric adenocarcinoma risk.
Author: Rostami, Masoumeh|Kalaei, Zahra|Pourhoseingholi, Mohamad Amin|Kadivar, Mehdi
PMID: 24834262
Journal: Med Res Rev. 2014 Mar;34(2):280-300.
Title: FGF receptors: cancer biology and therapeutics.
Author: Katoh, Masaru|Nakagama, Hitoshi
PMID: 23696246
Journal: Int J Cancer. 2014 Jan 1;134(1):114-24.
Title: Decreased Muc5AC expression is associated with poor prognosis in gastric cancer.
Author: Kim, Sung Mi|Kwon, Chae Hwa|Shin, Nari|Park, Do Youn|Moon, Hyun Jung|Kim, Gwang Ha|Jeon, Tae Yong
PMID: 23801416
Journal: Oncogene. 2014 Jun 19;33(25):3334-41.
Title: Testican-1-mediated epithelial-mesenchymal transition signaling confers acquired resistance to lapatinib in HER2-positive gastric cancer.
Author: Kim, H-P|Han, S-W|Song, S-H|Jeong, E-G|Lee, M-Y|Hwang, D|Im, S-A|Bang, Y-J|Kim, T-Y
PMID: 23873022
Journal: Gastric Cancer. 2014;17(3):450-62.
Title: Lapatinib sensitivities of two novel trastuzumab-resistant HER2 gene-amplified gastric cancer cell lines.
Author: Oshima, Yukiko|Tanaka, Harunari|Murakami, Hiroki|Ito, Yuichi|Furuya, Tomomi|Kondo, Eisaku|Kodera, Yasuhiro|Nakanishi, Hayao
PMID: 23948998
Journal: Cell Biol Int. 2014 Apr;38(4):502-10.
Title: PEITC reverse multi-drug resistance of human gastric cancer SGC7901/DDP cell line.
Author: Tang, Tao|Song, Xin|Liu, Yu-Fen|Wang, Wen-Yue
PMID: 23956061
Journal: Pathobiology. 2014;81(1):36-41.
Title: AKT activation and telomerase reverse transcriptase expression are concurrently associated with prognosis of gastric cancer.
Author: Sasaki, Takamitsu|Kuniyasu, Hiroki|Luo, Yi|Kitayoshi, Misaho|Tanabe, Eriko|Kato, Daisuke|Shinya, Satoshi|Fujii, Kiyomu|Ohmori, Hitoshi|Yamashita, Yuichi
PMID: 23969493
Journal: Tumour Biol. 2014 Feb;35(2):1287-95.
Title: miR-34a regulates cisplatin-induce gastric cancer cell death by modulating PI3K/AKT/survivin pathway.
Author: Cao, Weiguo|Yang, Weiping|Fan, Rong|Li, Hao|Jiang, Jinsong|Geng, Mei|Jin, Yening|Wu, Yunlin
PMID: 24068565
Journal: Mol Cell Biochem. 2014 Jan;386(1-2):143-52.
Title: Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells.
Author: Wang, Da-Guang|Sun, Ya-Bin|Ye, Fei|Li, Wei|Kharbuja, Punyaram|Gao, Ling|Zhang, David Y|Suo, Jian
PMID: 24136460
Journal: Ann Surg Oncol. 2014 Jan;21(1):343-50.
Title: The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab.
Author: Eto, Kojiro|Iwatsuki, Masaaki|Watanabe, Masayuki|Ida, Satoshi|Ishimoto, Takatsugu|Iwagami, Shiro|Baba, Yoshifumi|Sakamoto, Yasuo|Miyamoto, Yuji|Yoshida, Naoya|Baba, Hideo
PMID: 24154840
Journal: FEBS J. 2014 Jan;281(1):115-28.
Title: Up-regulation of survivin by AKT and hypoxia-inducible factor 1alpha contributes to cisplatin resistance in gastric cancer.
Author: Sun, Xue-Pu|Dong, Xuesong|Lin, Lele|Jiang, Xian|Wei, Zheng|Zhai, Bo|Sun, Bo|Zhang, Qiang|Wang, Xiaolong|Jiang, Hongchi|Krissansen, Geoffrey W|Qiao, Haiquan|Sun, Xueying
PMID: 24165223
Journal: Biomed Pharmacother. 2014 Mar;68(2):179-83.
Title: Tamoxifen reduces P-gp-mediated multidrug resistance via inhibiting the PI3K/Akt signaling pathway in ER-negative human gastric cancer cells.
Author: Mao, Zonglei|Zhou, Jin|Luan, Junwei|Sheng, Weihua|Shen, Xiaochun|Dong, Xiaoqiang
PMID: 24184201
Journal: Gastric Cancer. 2014;17(3):423-30.
Title: The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway.
Author: Park, Jinju|Ko, Young San|Yoon, Jiyeon|Kim, Min A|Park, Jong-Wan|Kim, Woo Ho|Choi, Youngsun|Kim, Ji Hun|Cheon, Younghee|Lee, Byung Lan
PMID: 24202965
Journal: Cancer Biol Ther. 2014 Jan;15(1):128-34.
Title: Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target.
Author: Li, Jing|Han, Sufang|Qian, Ziliang|Su, Xinying|Fan, Shuqiong|Fu, Jiangang|Liu, Yuanjie|Yin, Xiaolu|Gao, Zeren|Zhang, Jingchuan|Yu, De-Hua|Ji, Qunsheng
PMID: 24253382
Journal: Oncogene. 2014 Nov 13;33(46):5341-7.
Title: PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling.
Author: Yun, S M|Yoon, K|Lee, S|Kim, E|Kong, S-H|Choe, J|Kang, J M|Han, T-S|Kim, P|Choi, Y|Jho, S|Yoo, H|Bhak, J|Yang, H-K|Kim, S-J
PMID: 24276243
Journal: Oncol Rep. 2014 Feb;31(2):812-8.
Title: Knockdown of Slit2 promotes growth and motility in gastric cancer cells via activation of AKT/beta-catenin.
Author: Shi, Rongliang|Yang, Zhen|Liu, Weiyan|Liu, Bingya|Xu, Ziping|Zhang, Ziping
PMID: 24297051
Journal: Anticancer Drugs. 2014 Mar;25(3):315-22.
Title: Trastuzumab and oxaliplatin exhibit a synergistic antitumor effect in HER2-postive gastric cancer cells.
Author: Ding, Xiaodi|Qu, Xiujuan|Fan, Yibo|Che, Xiaofang|Qu, Jinglei|Xu, Ling|Liu, Jing|Liu, Yunpeng
PMID: 24300914
Journal: Mol Cancer Res. 2014 Mar;12(3):313-21.
Title: miR-338-3p suppresses gastric cancer progression through a PTEN-AKT axis by targeting P-REX2a.
Author: Guo, Bo|Liu, Liying|Yao, Jiayi|Ma, Ruili|Chang, Dongmin|Li, Zongfang|Song, Tusheng|Huang, Chen
PMID: 24375644
Journal: J Transl Med. 2014 Jan 4;12:1.
Title: XB130 promotes proliferation and invasion of gastric cancer cells.
Author: Shi, Min|Zheng, Dayong|Sun, Li|Wang, Lin|Lin, Li|Wu, Yajun|Zhou, Minyu|Liao, Wenjun|Liao, Yulin|Zuo, Qiang|Liao, Wangjun
PMID: 24387290
Journal: Tumour Biol. 2014 May;35(5):4389-99.
Title: CEP55 contributes to human gastric carcinoma by regulating cell proliferation.
Author: Tao, Jinqiu|Zhi, Xiaofei|Tian, Yuan|Li, Zheng|Zhu, Yi|Wang, Weizhi|Xie, Kunling|Tang, Jie|Zhang, Xiaoyu|Wang, Linjun|Xu, Zekuan
PMID: 24390615
Journal: Oncol Rep. 2014 Mar;31(3):1489-97.
Title: DJ-1 is involved in the peritoneal metastasis of gastric cancer through activation of the Akt signaling pathway.
Author: Zhu, Zheng-Ming|Li, Zheng-Rong|Huang, Yan|Yu, Hai-Hong|Huang, Xiao-Shan|Yan, Yu-Feng|Shao, Jiang-Hua|Chen, He-Ping
PMID: 24398929
Journal: PLoS One. 2014 Jan 9;9(1):e85116.
Title: The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.
Author: Ji, Dongmei|Zhang, Zhe|Cheng, Lei|Chang, Jinjia|Wang, Shanshan|Zheng, Biqiang|Zheng, Rongliang|Sun, Zuojun|Wang, Chenchen|Zhang, Zhiqing|Liu, Rujiao|Zhang, Xiaowei|Liu, Xin|Wang, Xiaofeng|Li, Jin
PMID: 24416349
Journal: Pharmacology. 2014;93(1-2):39-46.
Title: Celastrol induces apoptosis of gastric cancer cells by miR-21 inhibiting PI3K/Akt-NF-kappaB signaling pathway.
Author: Sha, Min|Ye, Jun|Zhang, Li-xin|Luan, Zheng-yun|Chen, Ya-bao|Huang, Jun-xing
PMID: 24434352
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1502-12.
Title: hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
Author: Crociani, Olivia|Lastraioli, Elena|Boni, Luca|Pillozzi, Serena|Romoli, Maria Raffaella|D'Amico, Massimo|Stefanini, Matteo|Crescioli, Silvia|Masi, Alessio|Taddei, Antonio|Bencini, Lapo|Bernini, Marco|Farsi, Marco|Beghelli, Stefania|Scarpa, Aldo|Messerini,
PMID: 24449824
Journal: Digestion. 2014;89(1):12-7.
Title: HER2 expression and PI3K-Akt pathway alterations in gastric cancer.
Author: Sukawa, Yasutaka|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Ito, Miki|Igarashi, Hisayoshi|Naito, Takafumi|Mitsuhashi, Kei|Matsunaga, Yasutaka|Takahashi, Taiga|Mikami, Masashi|Adachi, Yasushi|Suzuki, Hiromu|Shinomura, Yasuhisa
PMID: 24458107
Journal: Oncol Rep. 2014 Apr;31(4):1645-52.
Title: Inactivation of Akt by arsenic trioxide induces cell death via mitochondrial-mediated apoptotic signaling in SGC-7901 human gastric cancer cells.
Author: Gao, Yan-Hui|Zhang, Hao-Peng|Yang, Shu-Meng|Yang, Yue|Ma, Yu-Yan|Zhang, Xin-Yu|Yang, Yan-Mei
PMID: 24482137
Journal: MAbs. 2014 Mar-Apr;6(2):403-8.
Title: The ErbB2-targeting antibody trastuzumab and the small-molecule SRC inhibitor saracatinib synergistically inhibit ErbB2-overexpressing gastric cancer.
Author: Han, Siqi|Meng, Yanchun|Tong, Qing|Li, Guangchao|Zhang, Xunmin|Chen, Yalin|Hu, Shi|Zheng, Lei|Tan, Wenlong|Li, Hui|Chen, Yang|Zhang, Ge|Li, Bohua|Guo, Yajun
PMID: 24492292
Journal: Mol Med Rep. 2014 Apr;9(4):1371-5.
Title: Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.
Author: Yang, Gongli|Ma, Feng|Zhong, Muxiao|Fang, Lin|Peng, Yao|Xin, Xiaoming|Zhong, Jietao|Zhu, Wei|Zhang, Yali
PMID: 24504547
Journal: Oncogenesis. 2014 Feb 24;2:e89.
Title: The essential role of TNIK gene amplification in gastric cancer growth.
Author: Yu, D-H|Zhang, X|Wang, H|Zhang, L|Chen, H|Hu, M|Dong, Z|Zhu, G|Qian, Z|Fan, J|Su, X|Xu, Y|Zheng, L|Dong, H|Yin, X|Ji, Q|Ji, J
PMID: 24566388
Journal: Int J Mol Med. 2014 May;33(5):1177-84.
Title: 1,25-Dihydroxyvitamin D(3) and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells.
Author: Bao, Anyu|Li, Yan|Tong, Yongqing|Zheng, Hongyun|Wu, Wei|Wei, Chuandong
PMID: 24573222
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Feb;17(2):168-74.
Title: [Relationship between CD133 and chemoresistance in human gastric cancer and its associated mechanism].
Author: Zhu, Youlong|Jiang, Bojian|Cai, Cheng|Wang, Shoulian|Wu, Jugang|Yu, Jiwei
PMID: 24577774
Journal: World J Gastroenterol. 2014 Feb 28;20(8):2042-50.
Title: Targeted therapy in gastric cancer: personalizing cancer treatment based on patient genome.
Author: Lim, Sun Min|Lim, Jae Yun|Cho, Jae Yong
PMID: 24587678
Journal: Clin Cancer Res. 2014 May 1;20(9):2276-88.
Title: Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis.
Author: Tsai, Chung-Ying|Wang, Chia-Siu|Tsai, Ming-Ming|Chi, Hsiang-Cheng|Cheng, Wan-Li|Tseng, Yi-Hsin|Chen, Cheng-Yi|Lin, Crystal D|Wu, Jun-I|Wang, Lu-Hai|Lin, Kwang-Huei
PMID: 24602839
Journal: Int J Cancer. 2014 Sep 15;135(6):1390-8.
Title: Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer.
Author: Mimura, Kousaku|Kamiya, Takahiro|Shiraishi, Kensuke|Kua, Ley-Fang|Shabbir, Asim|So, Jimmy|Yong, Wei-Peng|Suzuki, Yoshiyuki|Yoshimoto, Yuya|Nakano, Takashi|Fujii, Hideki|Campana, Dario|Kono, Koji
PMID: 24615495
Journal: Med Oncol. 2014 Apr;31(4):903.
Title: Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway.
Author: Wu, Xiaoyu|Chen, Yun|Li, Gang|Xia, Lei|Gu, Rongmin|Wen, Xu|Ming, Xuezhi|Chen, Huanqiu
PMID: 24623015
Journal: BMB Rep. 2014 Dec;47(12):697-702.
Title: Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy.
Author: Lee, Hyun-Woo|Jang, Kenny Seung Bin|Choi, Hye Ji|Jo, Ara|Cheong, Jae-Ho|Chun, Kyung-Hee
PMID: 24667175
Journal: Int J Mol Med. 2014 Jun;33(6):1451-8.
Title: Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells.
Author: Liu, Min|Li, Chun-Mei|Chen, Zhao-Feng|Ji, Ri|Guo, Qing-Hong|Li, Qiang|Zhang, Hong-Ling|Zhou, Yong-Ning
PMID: 24676394
Journal: Arch Med Sci. 2014 Feb 24;10(1):149-53.
Title: Prognostic role of phospho-PRAS40 (Thr246) expression in gastric cancer.
Author: Lu, Yi-Zhuo|Deng, An-Mei|Li, Liang-Hui|Liu, Guo-Yan|Wu, Guo-Yang
PMID: 24701227
Journal: Cancer Sci. 2014 Jun;105(6):651-9.
Title: MGr1-Ag/37LRP induces cell adhesion-mediated drug resistance through FAK/PI3K and MAPK pathway in gastric cancer.
Author: Sun, Li|Liu, Lili|Liu, Xiangqiang|Wang, Yafang|Li, Mengbin|Yao, Liping|Yang, Jianjun|Ji, Genlin|Guo, Changcun|Pan, Yanglin|Liang, Shuhui|Wang, Biaoluo|Ding, Jie|Zhang, Hongwei|Shi, Yongquan
PMID: 24703465
Journal: Biomed Pharmacother. 2014 May;68(4):471-5.
Title: Clinicopathological significance of PI3K, Akt and survivin expression in gastric cancer.
Author: Gu, Yongjuan|Jin, Shidai|Wang, Feng|Hua, Yibin|Yang, Li|Shu, Yongqian|Zhang, Zhihong|Guo, Renhua
PMID: 24726064
Journal: PLoS One. 2014 Apr 15;9(4):e94422.
Title: MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression.
Author: Peng, Yang|Liu, Yan-Min|Li, Lu-Chun|Wang, Lu-Lu|Wu, Xiao-Ling
PMID: 24736504
Journal: J Cancer Res Clin Oncol. 2014 Aug;140(8):1399-411.
Title: A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Author: Wang, Xiaoting|Lin, Youdong|Lan, Fenghua|Yu, Yinghao|Ouyang, Xuenong|Wang, Xuzhou|Huang, Qiaojia|Wang, Lie|Tan, Jianming|Zheng, Feng
PMID: 24737346
Journal: J Cancer Res Clin Oncol. 2014 Jul;140(7):1117-24.
Title: SOX2 oncogenes amplified and operate to activate AKT signaling in gastric cancer and predict immunotherapy responsiveness.
Author: Tian, Yajun|Jia, Xin|Wang, Shengxiang|Li, Yongsheng|Zhao, Peng|Cai, Da|Zhou, Zequan|Wang, Junmin|Luo, Yi|Dong, Maosheng
PMID: 24752338
Journal: Sci Signal. 2014 Apr 22;7(322):ra38.
Title: Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer.
Author: Lai, Andrea Z|Cory, Sean|Zhao, Hong|Gigoux, Mathieu|Monast, Anie|Guiot, Marie-Christine|Huang, Sidong|Tofigh, Ali|Thompson, Crista|Naujokas, Monica|Marcus, Victoria A|Bertos, Nicholas|Sehat, Bita|Perera, Rushika M|Bell, Emily S|Page, Brent D G|Gunning, Pa
PMID: 24757178
Journal: Oncol Lett. 2014 May;7(5):1401-1408.
Title: Inhibition of phosphoinositide 3-kinase/Akt pathway decreases hypoxia inducible factor-1alpha expression and increases therapeutic efficacy of paclitaxel in human hypoxic gastric cancer cells.
Author: Zhang, Jing|Guo, Hua|Zhu, Jin-Shui|Yang, Yu-Chen|Chen, Wei-Xiong|Chen, Ni-Wei
PMID: 24765145
Journal: BMC Res Notes. 2014 Apr 29;7:271.
Title: Clinicopathological features and prognostic roles of KRAS, BRAF, PIK3CA and NRAS mutations in advanced gastric cancer.
Author: Takahashi, Naoki|Yamada, Yasuhide|Taniguchi, Hirokazu|Fukahori, Masaru|Sasaki, Yusuke|Shoji, Hirokazu|Honma, Yoshitaka|Iwasa, Satoru|Takashima, Atsuo|Kato, Ken|Hamaguchi, Tetsuya|Shimada, Yasuhiro
PMID: 24774510
Journal: J Cancer. 2014 Apr 24;5(5):382-9.
Title: Carnosine Inhibits the Proliferation of Human Gastric Carcinoma Cells by Retarding Akt/mTOR/p70S6K Signaling.
Author: Zhang, Zhenwei|Miao, Lei|Wu, Xin|Liu, Guangze|Peng, Yuting|Xin, Xiaoming|Jiao, Binghua|Kong, Xiangping
PMID: 24799956
Journal: Int J Clin Exp Pathol. 2014 Mar 15;7(4):1449-58. eCollection 2014.
Title: AKT/ERK activation is associated with gastric cancer cell resistance to paclitaxel.
Author: Wu, Gang|Qin, Xue-Qian|Guo, Jing-Jing|Li, Tian-Yi|Chen, Jin-Hong
PMID: 24817940
Journal: Pharm Biol. 2014 Jun;52(6):789-95.
Title: Oleanolic acid induces apoptosis of MKN28 cells via AKT and JNK signaling pathways.
Author: Lu, Yunmin|Zhu, Meiying|Chen, Wei|Yin, Li|Zhu, Jinshui|Chen, Niwei|Chen, Weixiong
PMID: 24824325
Journal: Biosci Rep. 2014 Jun 25;34(3). pii: BSR20140020.
Title: MicroRNA-34A inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expression.
Author: Peng, Yang|Guo, Jin-Jun|Liu, Yan-Min|Wu, Xiao-Ling
PMID: 24837198
Journal: Virchows Arch. 2014 Jul;465(1):25-33.
Title: The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance.
Author: Tapia, Oscar|Riquelme, Ismael|Leal, Pamela|Sandoval, Alejandra|Aedo, Susana|Weber, Helga|Letelier, Pablo|Bellolio, Enrique|Villaseca, Miguel|Garcia, Patricia|Roa, Juan Carlos
PMID: 24844205
Journal: Tumour Biol. 2014 Aug;35(8):8217-23.
Title: Molecular basis underlying inhibition of metastasis of gastric cancer by anti-VEGFa treatment.
Author: Mao, Dong|Zhang, Yun|Lu, Hang|Zhang, Hong
PMID: 24850176
Journal: Cell Physiol Biochem. 2014;33(5):1359-68.
Title: Down-regulated MAC30 expression inhibits proliferation and mobility of human gastric cancer cells.
Author: Xu, Xiao-Yan|Zhang, Li-Juan|Yu, Yan-Qiu|Zhang, Xiao-Tong|Huang, Wan-jing|Nie, Xiao-Cui|Song, Guo-Qing
PMID: 24853233
Journal: Int J Oncol. 2014 Aug;45(2):771-81.
Title: A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.
Author: Wang, Tian-En|Wang, Yong-Kang|Jin, Jing|Xu, Bai-Ling|Chen, Xiao-Guang
PMID: 24859921
Journal: Mol Cancer. 2014 Jun 2;13:136.
Title: Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells.
Author: Li, Heming|Xu, Ling|Li, Ce|Zhao, Lei|Ma, Yanju|Zheng, Huachuan|Li, Zhi|Zhang, Ye|Wang, Ruoyu|Liu, Yunpeng|Qu, Xiujuan
PMID: 24885194
Journal: J Exp Clin Cancer Res. 2014 May 3;33:38.
Title: Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer.
Author: Chen, Jia|Wang, Tao|Zhou, Yang-Chun|Gao, Fei|Zhang, Zhi-Hong|Xu, Hao|Wang, Shou-Lin|Shen, Li-Zong
PMID: 24887009
Journal: Nutr Cancer. 2014;66(6):938-45.
Title: Escin suppresses migration and invasion involving the alteration of CXCL16/CXCR6 axis in human gastric adenocarcinoma AGS cells.
Author: Lee, Hyun Sook|Hong, Ji Eun|Kim, Eun Ji|Kim, Sun Hyo
PMID: 24911042
Journal: Nucleic Acids Res. 2014 Jul;42(12):8062-72.
Title: MicroRNA-382 induced by HIF-1alpha is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog.
Author: Seok, Jin-Kyung|Lee, Sun Hee|Kim, Min Jung|Lee, You-Mie
PMID: 24914051
Journal: Tumour Biol. 2014 Sep;35(9):9139-46.
Title: Anti-tumor activity of oridonin on SNU-5 subcutaneous xenograft model via regulation of c-Met pathway.
Author: Liu, Hua|Qian, Changlin|Shen, Zhiyong
PMID: 24916572
Journal: PLoS One. 2014 Jun 19;9(6):e99922.
Title: Epidermal growth factor-like domain-containing protein 7 (EGFL7) enhances EGF receptor-AKT signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.
Author: Luo, Bai-Hua|Xiong, Feng|Wang, Jun-Pu|Li, Jing-He|Zhong, Ming|Liu, Qin-Lai|Luo, Geng-Qiu|Yang, Xiao-Jing|Xiao, Ni|Xie, Bin|Xiao, Heng|Liu, Rui-Jie|Dong, Chang-Sheng|Wang, Kuan-Song|Wen, Ji-Fang
PMID: 24945379
Journal: PLoS One. 2014 Jun 26;9(6):e98515.
Title: FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Author: Mathur, Anjili|Ware, Christopher|Davis, Lenora|Gazdar, Adi|Pan, Bo-Sheng|Lutterbach, Bart
PMID: 24968263
Journal: Oncol Rep. 2014 Sep;32(3):973-8.
Title: Anti-apoptotic and apoptotic pathway analysis of arsenic trioxideinduced apoptosis in human gastric cancer SGC-7901 cells.
Author: Yu, Yao|Yang, Yu|Wang, Jing
PMID: 24969414
Journal: Oncotarget. 2014 Jul 15;5(13):4959-71.
Title: miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT.
Author: Liu, Nianli|Zuo, Chaohui|Wang, Xiaohong|Chen, Tianran|Yang, Darong|Wang, Jing|Zhu, Haizhen
PMID: 24970806
Journal: Clin Cancer Res. 2014 Sep 1;20(17):4559-73.
Title: Functional genetic approach identifies MET, HER3, IGF1R, INSR pathways as determinants of lapatinib unresponsiveness in HER2-positive gastric cancer.
Author: Zhang, Zhe|Wang, Jiping|Ji, Dongmei|Wang, Chenchen|Liu, Rujiao|Wu, Zheng|Liu, Lian|Zhu, Dan|Chang, Jinjia|Geng, Ruixuan|Xiong, Lei|Fang, Qiangyi|Li, Jin
PMID: 24973425
Journal: Tumour Biol. 2014 Oct;35(10):9801-6.
Title: MiRNA-34a inhibits EGFR-signaling-dependent MMP7 activation in gastric cancer.
Author: Liu, Gang|Jiang, Chuanshen|Li, Dazhou|Wang, Rong|Wang, Wen
PMID: 24981249
Journal: Scientifica (Cairo). 2014;2014:903014.
Title: XB130-A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis.
Author: Bai, Xiao-Hui|Cho, Hae-Ra|Moodley, Serisha|Liu, Mingyao
PMID: 24995146
Journal: Cancers (Basel). 2014 Jul 7;6(3):1441-63.
Title: The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma.
Author: Matsuoka, Tasuku|Yashiro, Masakazu
PMID: 25003395
Journal: Biomol Ther (Seoul). 2014 May;22(3):184-92.
Title: beta-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway.
Author: Yu, Hai Yang|Kim, Sung Ok|Jin, Cheng-Yun|Kim, Gi-Young|Kim, Wun-Jae|Yoo, Young Hyun|Choi, Yung Hyun
PMID: 25009698
Journal: Oncotarget. 2014 Jul 30;5(14):5798-807.
Title: Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells.
Author: Liang, Xiuming|Zeng, Jiping|Wang, Lixiang|Shen, Li|Li, Shuyan|Ma, Lin|Ci, Xinyu|Yu, Jingya|Jia, Mutian|Sun, Yundong|Liu, Zhifang|Liu, Shili|Li, Wenjuan|Yu, Han|Chen, Chunyan|Jia, Jihui
PMID: 25015565
Journal: Int J Clin Exp Pathol. 2014 May 15;7(6):3312-7. eCollection 2014.
Title: Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas.
Author: Sangawa, Akiko|Shintani, Michiko|Yamao, Naoki|Kamoshida, Shingo
PMID: 25031754
Journal: Anticancer Drugs. 2014 Nov;25(10):1129-40.
Title: PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway.
Author: Xing, Xiaofang|Zhang, Lianhai|Wen, Xianzi|Wang, Xiaohong|Cheng, Xiaojing|Du, Hong|Hu, Ying|Li, Lin|Dong, Bin|Li, Ziyu|Ji, Jiafu
PMID: 25035961
Journal: Molecules. 2014 Jul 24;19(8):10818-31.
Title: Cudarflavone B provides neuroprotection against glutamate-induced mouse hippocampal HT22 cell damage through the Nrf2 and PI3K/Akt signaling pathways.
Author: Lee, Dong-Sung|Ko, Wonmin|Kim, Dong-Cheol|Kim, Youn-Chul|Jeong, Gil-Saeng
PMID: 25061726
Journal: Tumour Biol. 2014 Nov;35(11):10891-6.
Title: Inhibition of epidermal growth factor receptor signaling prohibits metastasis of gastric cancer via downregulation of MMP7 and MMP13.
Author: Ye, Yinghai|Zhou, Xiaocong|Li, Xiaoyang|Tang, Yinhe|Sun, Yusheng|Fang, Jun
PMID: 25085584
Journal: J Biol Chem. 2014 Oct 3;289(40):27776-93.
Title: Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor kappaB-activated tumor necrosis factor-alpha production via regulation of p65 serine 536 phosphorylation.
Author: Ahmed, Afsar U|Sarvestani, Soroush T|Gantier, Michael P|Williams, Bryan R G|Hannigan, Gregory E
PMID: 25100717
Journal: Oncol Rep. 2014 Oct;32(4):1369-73.
Title: SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling.
Author: Xiong, Huaping|Wang, Jicheng|Guan, Hongyu|Wu, Jueheng|Xu, Ru|Wang, Min|Rong, Xia|Huang, Ke|Huang, Jieting|Liao, Qiao|Fu, Yongshui|Yuan, Jie
PMID: 25109605
Journal: Pol J Pathol. 2014 Jun;65(2):135-40.
Title: Expression of insulin-like growth factor receptor type 1 correlate with lymphatic metastases in human gastric cancer.
Author: Gryko, M|Kisluk, J|Cepowicz, D|Zinczuk, J|Kamocki, Z|Guzinska-Ustymowicz, K|Pryczynicz, A|Czyzewska, J|Kemona, A|Kedra, B
PMID: 25119174
Journal: Int J Clin Exp Pathol. 2014 Jun 15;7(7):3694-703. eCollection 2014.
Title: IL-22 promotes the migration and invasion of gastric cancer cells via IL-22R1/AKT/MMP-9 signaling.
Author: Ji, Yinghua|Yang, Xiaoyu|Li, Jinsong|Lu, Zhihong|Li, Xiaorui|Yu, Jian|Li, Na
PMID: 25120745
Journal: Tumour Biol. 2014 Dec;35(12):12021-30.
Title: A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy.
Author: Chun, Jaemoo|Kang, Minseok|Kim, Yeong Shik
PMID: 25146681
Journal: Neoplasma. 2014;61(6):627-37.
Title: Annexin A2 is implicated in multi-drug-resistance in gastric cancer through p38MAPK and AKT pathway.
Author: Zhang, Z D|Li, Y|Fan, Q|Zhao, B|Tan, B|Zhao, X F
PMID: 25150310
Journal: Mol Med Rep. 2014 Nov;10(5):2459-64.
Title: Calcium/calmodulindependent protein kinase II enhances metastasis of human gastric cancer by upregulating nuclear factorkappaB and Aktmediated matrix metalloproteinase9 production.
Author: Liu, Zhaolong|Han, Gang|Cao, Yu|Wang, Yidong|Gong, Hangjun
PMID: 25174603
Journal: Biomed Pharmacother. 2014 Jul;68(6):809-12.
Title: The role of HER3 in gastric cancer.
Author: Wang, Liying|Yuan, Hengheng|Li, Yanjing|Han, Yu
PMID: 25194439
Journal: Mol Med Rep. 2014 Nov;10(5):2729-35.
Title: Suberoylanilide hydroxamic acid enhances the antitumor activity of oxaliplatin by reversing the oxaliplatininduced Src activation in gastric cancer cells.
Author: Zhou, Chenfei|Ji, Jun|Shi, Min|Yang, Liu|Yu, Yingyan|Liu, Bingya|Zhu, Zhenggang|Zhang, Jun
PMID: 25199623
Journal: Oncol Rep. 2014 Dec;32(6):2437-44.
Title: Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells.
Author: Zhu, Youlong|Yu, Jiwei|Wang, Shoulian|Lu, Ruiqi|Wu, Jugang|Jiang, Bojian
PMID: 25230779
Journal: Int J Oncol. 2014 Dec;45(6):2187-92.
Title: Significance of AKT in gastric cancer (Review).
Author: Sasaki, Takamitsu|Kuniyasu, Hiroki
PMID: 25270272
Journal: PLoS One. 2014 Oct 6;9(10):e107362.
Title: Mechanisms of GOLPH3 associated with the progression of gastric cancer: a preliminary study.
Author: Peng, Jinzhen|Fang, Ye|Tao, Yong|Li, Keke|Su, Ting|Nong, Yuncui|Xie, Fang|Lai, Mingyu
PMID: 25286393
Journal: J Transl Med. 2014 Oct 5;12:281.
Title: let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis.
Author: Kang, Wei|Tong, Joanna H M|Lung, Raymond W M|Dong, Yujuan|Yang, Weiqin|Pan, Yi|Lau, Kin Mang|Yu, Jun|Cheng, Alfred Sl|To, Ka Fai
PMID: 25288334
Journal: Oncol Lett. 2014 Nov;8(5):2077-2080.
Title: Involvement of the Akt signaling pathway in ER-alpha36/GRP94-mediated signaling in gastric cancer.
Author: Fu, Zhengqi|Zhen, Hongyan|Zou, Feng|Wang, Xuming|Chen, Ying|Liu, Lijiang
PMID: 25295093
Journal: Oncotarget. 2014 Nov 15;5(21):10584-95.
Title: Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9.
Author: Zhang, Bao-gui|Du, Tao|Zang, Ming-de|Chang, Qing|Fan, Zhi-yuan|Li, Jian-fang|Yu, Bei-qin|Su, Li-ping|Li, Chen|Yan, Chao|Gu, Qin-long|Zhu, Zheng-gang|Yan, Min|Liu, Bingya
PMID: 25301736
Journal: J Gastric Cancer. 2014 Sep;14(3):147-55.
Title: The role of gastrokine 1 in gastric cancer.
Author: Yoon, Jung Hwan|Choi, Won Suk|Kim, Olga|Park, Won Sang
PMID: 25328759
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Oct;17(10):1031-5.
Title: [Influence of 17AAG on proliferation and invasion of gastric cancer cell and its mechanism].
Author: Cui, Yuehong|Yu, Yiyi|Liu, Tianshu|Xie, Qian|Wu, Weizhong|Liu, Kangda
PMID: 25341914
Journal: Mar Drugs. 2014 Oct 23;12(10):5295-315.
Title: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.
Author: Su, Ching-Chyuan|Chen, Jeff Yi-Fu|Din, Zhong-Hao|Su, Jui-Hsin|Yang, Zih-Yan|Chen, Yi-Jen|Wang, Robert Y L|Wu, Yu-Jen
PMID: 25342459
Journal: Int J Clin Exp Med. 2014 Sep 15;7(9):3037-44. eCollection 2014.
Title: Regenerating gene family member 4 promotes growth and migration of gastric cancer through protein kinase B pathway.
Author: Huang, Jiamiao|Yang, Ya|Yang, Jian|Li, Xian
PMID: 25356179
Journal: Chin J Integr Med. 2014 Nov 10.
Title: Extracts of Celastrus orbiculatus exhibit anti-proliferative and anti-invasive effects on human gastric adenocarcinoma cells.
Author: Zhu, Yao-Dong|Liu, Yan-Qing|Qian, Ya-Yun|Zhang, Hua|Li, Guo-Qing|Yang, Lin
PMID: 25382615
Journal: Cancer Gene Ther. 2014 Nov;21(11):491-7.
Title: Knockdown of EGFR inhibits growth and invasion of gastric cancer cells.
Author: Zhen, Y|Guanghui, L|Xiefu, Z
PMID: 25394504
Journal: PLoS One. 2014 Nov 14;9(11):e112908.
Title: CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.
Author: Zang, Mingde|Zhang, Baogui|Zhang, Yunqiang|Li, Jianfang|Su, Liping|Zhu, Zhenggang|Gu, Qinlong|Liu, Bingya|Yan, Min
PMID: 25398131
Journal: Int J Clin Exp Pathol. 2014 Sep 15;7(10):7286-96. eCollection 2014.
Title: MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer.
Author: Lu, Weidong|Xu, Zhen|Zhang, Min|Zuo, Yun
PMID: 25400827
Journal: Oncotarget. 2014 Dec 15;5(23):11873-85.
Title: Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A.
Author: Chen, Hongxia|Li, Lingmin|Wang, Shaojun|Lei, Yupeng|Ge, Qi|Lv, Nonghua|Zhou, Xiaodong|Chen, Changyan
PMID: 25428912
Journal: Cancer Gene Ther. 2014 Dec;21(12):526-31.
Title: Inhibition of Vav3 could reverse the drug resistance of gastric cancer cells by downregulating JNK signaling pathway.
Author: Tan, B|Li, Y|Zhao, Q|Fan, L|Liu, Y|Wang, D|Zhao, X
PMID: 25430880
Journal: Cancer Cell Int. 2014 Dec 5;14(1):135.
Title: Activation of EGFR-PI3K-AKT signaling is required for Mycoplasma hyorhinis-promoted gastric cancer cell migration.
Author: Duan, Hongying|Qu, Like|Shou, Chengchao
PMID: 25505372
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2014 Dec;34(12):1748-52.
Title: [Effect of miR-92b on migration, adhesion and invasion of human gastric cancer cell line SGC7901].
Author: Wang, Weihua|Wang, Changzheng|Jiang, Yi|Wu, Benyan
PMID: 25537895
Journal: Int J Hematol Oncol Stem Cell Res. 2014 Jul 1;8(3):12-9.
Title: Evaluation of antagonistic effects of metformin with Cisplatin in gastric cancer cells.
Author: Lesan, Vahid|Ghaffari, Seyed H|Salaramoli, Jamile|Heidari, Mansour|Rostami, Masoumeh|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir
PMID: 25642303
Journal: Mutat Res. 2014 Nov;769:108-12.
Title: Occurrence of low frequency PIK3CA and AKT2 mutations in gastric cancer.
Author: Zhang, Qing-Ying|Cheng, Wen-Xiang|Li, Wen-Mei|Au, William|Lu, You-Yong
PMID: 25771729
Journal: Oncol Res. 2014;22(5-6):267-73.
Title: Ursolic Acid Inhibits the Proliferation of Gastric Cancer Cells by Targeting miR-133a.
Author: Xiang, Fenfen|Pan, Chunying|Kong, Qianqian|Wu, Rong|Jiang, Jiemin|Zhan, Yueping|Xu, Jian|Gu, Xingang|Kang, Xiangdong
PMID: 26629938
Journal: Gastrointest Tumors. 2014 May;1(4):180-94.
Title: Gastric Cancer: New Drugs - New Strategies.
Author: Schulte, Nadin|Ebert, Matthias P|Hartel, Nicola
PMID: 26674336
Journal: Biosci Rep. 2014 Apr 1;34(2). pii: BSR20130102.
Title: PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways.
Author: Fu, Xueqiong|Feng, Jiarui|Zeng, Duan|Ding, Yu|Yu, Changshou|Yang, Bing
PMID: 27919028
Journal: Gastric Cancer. 2015 Jan;18(1):65-76.
Title: Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer.
Author: Yoda, Yukie|Takeshima, Hideyuki|Niwa, Tohru|Kim, Jeong Goo|Ando, Takayuki|Kushima, Ryoji|Sugiyama, Toshiro|Katai, Hitoshi|Noshiro, Hirokazu|Ushijima, Toshikazu
PMID: 24510342
Journal: Gut. 2015 Jul;64(7):1028-39.
Title: Activation of beta-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis.
Author: Soutto, Mohammed|Peng, DunFa|Katsha, Ahmed|Chen, Zheng|Piazuelo, Maria Blanca|Washington, Mary Kay|Belkhiri, Abbes|Correa, Pelayo|El-Rifai, Wael
PMID: 25107557
Journal: Int J Cancer. 2015 Apr 1;136(7):1629-35.
Title: HER2-positive gastric cancer with concomitant MET and/or EGFR overexpression: a distinct subset of patients for dual inhibition therapy.
Author: Ha, Sang Yun|Lee, Jeeyun|Jang, Jiryeon|Hong, Jung Yong|Do, In-Gu|Park, Se Hoon|Park, Joon Oh|Choi, Min-Gew|Sohn, Tae Sung|Bae, Jae Moon|Kim, Sung|Kim, Minji|Kim, Seonwoo|Park, Cheol Keun|Kang, Won Ki|Kim, Kyoung-Mee
PMID: 25157953
Journal: Oncol Rep. 2015 Jan;33(1):457-63.
Title: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway.
Author: Chen, Fenglin|Zhuang, Mingkai|Zhong, Canmei|Peng, Jun|Wang, Xiaozhong|Li, Jianying|Chen, Zhixin|Huang, Yuehong
PMID: 25333894
Journal: Mol Med Rep. 2015 Mar;11(3):2269-75.
Title: Downregulation of c-Met expression does not enhance the sensitivity of gastric cancer cell line MKN-45 to gefitinib.
Author: Ma, Jin-An|Hu, Chunhong|Li, Wenjuan|Ren, Jing|Zou, Fangwen|Zhou, Dongai|Zou, Wen|Wei, Yajun|Zhou, Ying
PMID: 25395073
Journal: Mol Carcinog. 2015 Dec;54(12):1700-9.
Title: Essential role of Her3 in two signaling transduction patterns: Her2/Her3 and MET/Her3 in proliferation of human gastric cancer.
Author: Yun, Chen|Gang, Li|Rongmin, Gu|Xu, Wen|Xuezhi, Ming|Huanqiu, Chen
PMID: 25400108
Journal: Med Oncol. 2015 Jan;32(1):342.
Title: MicroRNA-29s could target AKT2 to inhibit gastric cancer cells invasion ability.
Author: Zhang, Hongkai|Cheng, Yin|Jia, Congwei|Yu, Shuangni|Xiao, Yu|Chen, Jie
PMID: 25428377
Journal: Tumour Biol. 2015 Apr;36(4):2457-64.
Title: The human epididymis protein 4 acts as a prognostic factor and promotes progression of gastric cancer.
Author: Guo, Yun-Di|Wang, Jing-Hao|Lu, Huan|Li, Xiao-Ning|Song, Wei-Wei|Zhang, Xiao-Dan|Zhang, Wen-Ming
PMID: 25432133
Journal: Med Oncol. 2015 Jan;32(1):361.
Title: MicroRNA-542-3p suppresses cell growth of gastric cancer cells via targeting oncogene astrocyte-elevated gene-1.
Author: Shen, Xinsheng|Si, Yaqing|Yang, Zhugong|Wang, Qun|Yuan, Jiaxiang|Zhang, Xiefu
PMID: 25432696
Journal: Tumour Biol. 2015 Apr;36(4):2517-22.
Title: 1-butyltryptophan inhibits cell proliferation, migration, and invasion through the Akt pathway in human gastric cancer cells.
Author: Sun, Ting|Tian, Hua|Xin, YangXun
PMID: 25433499
Journal: Oncol Lett. 2015 Jan;9(1):143-148.
Title: Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3beta and ZEB2 in the BGC-823 gastric cancer cell line.
Author: Li, Heming|Xu, Ling|Zhao, Lei|Ma, Yanju|Zhu, Zhitu|Liu, Yunpeng|Qu, Xiujuan
PMID: 25435948
Journal: Tumour Biol. 2015 Apr;36(4):2773-8.
Title: Bone morphogenetic protein 2 mediates epithelial-mesenchymal transition via AKT and ERK signaling pathways in gastric cancer.
Author: Liao, Anyan|Wang, Weijie|Sun, Dawei|Jiang, Yuliang|Tian, Suqing|Li, Jinna|Yang, Xiangshan|Shi, Ranran
PMID: 25448881
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):704-12.
Title: Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-beta/beta-catenin signaling and epithelial-mesenchymal transition.
Author: Zhang, Bin|Yang, Yan|Shi, Xiaoting|Liao, Wanyu|Chen, Min|Cheng, Alfred Sze-Lok|Yan, Hongli|Fang, Cheng|Zhang, Shu|Xu, Guifang|Shen, Shanshan|Huang, Shuling|Chen, Guangxia|Lv, Ying|Ling, Tingsheng|Zhang, Xiaoqi|Wang, Lei|Zhuge, Yuzheng|Zou, Xiaoping
PMID: 25449432
Journal: Oncology. 2015;88(3):189-94.
Title: Loss of heterozygosity of PTEN (encoding phosphate and tensin homolog) associated with elevated HER2 expression is an adverse prognostic indicator in gastric cancer.
Author: Zaitsu, Yoko|Oki, Eiji|Ando, Koji|Ida, Satoshi|Kimura, Yasue|Saeki, Hiroshi|Morita, Masaru|Hirahashi, Minako|Oda, Yoshinao|Maehara, Yoshihiko
PMID: 25472613
Journal: Oncol Rep. 2015 Feb;33(2):868-74.
Title: Kaempferol inhibits gastric cancer tumor growth: An in vitro and in vivo study.
Author: Song, Haibin|Bao, Junjie|Wei, Yuzhe|Chen, Yang|Mao, Xiaoguang|Li, Jianguo|Yang, Zhiwei|Xue, Yingwei
PMID: 25500692
Journal: Med Oncol. 2015 Jan;32(1):447.
Title: The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions.
Author: Shen, Xinsheng|Xue, Yange|Si, Yaqing|Wang, Qun|Wang, Zhao|Yuan, Jiaxiang|Zhang, Xiefu
PMID: 25502090
Journal: Mol Cancer Ther. 2015 Feb;14(2):384-94.
Title: The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer.
Author: Egile, Coumaran|Kenigsberg, Mireille|Delaisi, Christine|Begassat, Francoise|Do-Vale, Veronique|Mestadier, Jessica|Bonche, Fabrice|Benard, Tsiala|Nicolas, Jean-Paul|Valence, Sandrine|Lefranc, Celine|Francesconi, Elisa|Castell, Christelle|Lefebvre, Anne-Mar
PMID: 25504634
Journal: Cancer Lett. 2015 Mar 1;358(1):17-26.
Title: Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: involvement of the Akt-mTOR signaling pathway.
Author: Zhao, Zhi|Han, Fanghai|Yang, Shibin|Wu, Jianhai|Zhan, Wenhua
PMID: 25524555
Journal: Cancer Chemother Pharmacol. 2015 Feb;75(2):353-63.
Title: Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.
Author: Guo, Bingyu|Zhang, Tingting|Su, Jingyuan|Wang, Kaiwen|Li, Xiaoming
PMID: 25527205
Journal: Tumour Biol. 2015 May;36(5):3237-43.
Title: Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell.
Author: Akrami, Hassan|Aminzadeh, Saman|Fallahi, Hossein
PMID: 25542229
Journal: Oncotarget. 2015 Jan 30;6(3):1652-65.
Title: Claudin-1 enhances tumor proliferation and metastasis by regulating cell anoikis in gastric cancer.
Author: Huang, Jie|Zhang, Li|He, Changyu|Qu, Ying|Li, Jianfang|Zhang, Jianian|Du, Tao|Chen, Xuehua|Yu, Yingyan|Liu, Bingya|Zhu, Zhenggang
PMID: 25544763
Journal: Med Oncol. 2015 Feb;32(2):467.
Title: CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in gastric cancer.
Author: Zhang, Jianping|Zhou, Yunzhe|Yang, Yonggang
PMID: 25572817
Journal: Med Oncol. 2015 Feb;32(2):470.
Title: Sorafenib reverses resistance of gastric cancer to treatment by cisplatin through down-regulating MDR1 expression.
Author: Huang, Yi-Sheng|Xue, Zhi|Zhang, Hua
PMID: 25579168
Journal: Mol Med Rep. 2015 May;11(5):3439-44.
Title: Effect of orexin A on apoptosis in BGC-823 gastric cancer cells via OX1R through the AKT signaling pathway.
Author: Wen, Jing|Zhao, Yuyan|Shen, Yang|Guo, Lei
PMID: 25586545
Journal: Cell Cycle. 2015;14(5):732-43.
Title: Frequent amplification of PTP1B is associated with poor survival of gastric cancer patients.
Author: Wang, Na|She, Junjun|Liu, Wei|Shi, Jing|Yang, Qi|Shi, Bingyin|Hou, Peng
PMID: 25590580
Journal: Tumour Biol. 2015 Jun;36(6):4519-23.
Title: Insulin-like growth factor 1 promotes growth of gastric cancer by inhibiting foxo1 nuclear retention.
Author: Li, Shuangling|Lei, Xiaofei|Zhang, Jianna|Yang, Hongli|Liu, Jiyong|Xu, Changqing
PMID: 25596089
Journal: Drug Des Devel Ther. 2015 Jan 14;9:487-508.
Title: Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
Author: Yuan, Chun-Xiu|Zhou, Zhi-Wei|Yang, Yin-Xue|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Tianxing|Wang, Ning-Ju|Zhao, Ruan Jin|Zhou, Shu-Feng
PMID: 25609923
Journal: Cancer Gene Ther. 2015 Apr;22(3):145-53.
Title: HER-2-induced PI3K signaling pathway was involved in the pathogenesis of gastric cancer.
Author: Fu, Y F|Gui, R|Liu, J
PMID: 25613482
Journal: Am J Cancer Res. 2014 Dec 15;5(1):87-100. eCollection 2015.
Title: KDM5B is overexpressed in gastric cancer and is required for gastric cancer cell proliferation and metastasis.
Author: Wang, Zhenran|Tang, Fang|Qi, Guangying|Yuan, Shengguang|Zhang, Guangyu|Tang, Bo|He, Songqing
PMID: 25628922
Journal: Oncol Rep. 2015 Apr;33(4):2031-6.
Title: 3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade.
Author: Jin, Hua|Park, Man Hee|Kim, Soo Mi
PMID: 25633416
Journal: Tumour Biol. 2015 Feb;36(2):521-32.
Title: The functional sites of miRNAs and lncRNAs in gastric carcinogenesis.
Author: Wan, Xiangxiang|Ding, Xiaoyun|Chen, Shengcan|Song, Haojun|Jiang, Haizhong|Fang, Ying|Li, Peifei|Guo, Junming
PMID: 25636450
Journal: J Transl Med. 2015 Feb 1;13:42.
Title: Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer.
Author: Lu, Jun|Li, Guangliang|He, Kuifeng|Jiang, Weiqin|Xu, Cong|Li, Zhongqi|Wang, Haohao|Wang, Weibin|Wang, Haiyong|Teng, Xiaodong|Teng, Lisong
PMID: 25638174
Journal: J Cell Biochem. 2015 Jun;116(6):1080-9.
Title: Inactivation of the phosphatidylinositol 3-kinase/Akt pathway is involved in BMP9-mediated tumor-suppressive effects in gastric cancer cells.
Author: Duan, Liang|Ye, Liwei|Wu, Rui|Wang, Haiyan|Li, Xueru|Li, Huan|Yuan, Shimei|Zha, He|Sun, Hui|Zhang, Yunyuan|Chen, Xian|Zhang, Yan|Zhou, Lan
PMID: 25640278
Journal: PLoS Pathog. 2015 Feb 3;11(2):e1004621.
Title: A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.
Author: Zhang, Xue-Song|Tegtmeyer, Nicole|Traube, Leah|Jindal, Shawn|Perez-Perez, Guillermo|Sticht, Heinrich|Backert, Steffen|Blaser, Martin J
PMID: 25646814
Journal: BMC Genomics. 2015 Feb 5;16:41.
Title: Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells.
Author: Lin, Li-Ling|Hsia, Chieh-Ren|Hsu, Chia-Lang|Huang, Hsuan-Cheng|Juan, Hsueh-Fen
PMID: 25652794
Journal: Oncol Rep. 2015 Apr;33(4):1630-8.
Title: Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2.
Author: Zhang, Qiu-Yu|Wu, Lin-Qing|Zhang, Tao|Han, Yan-Fei|Lin, Xu
PMID: 25652880
Journal: Oncotarget. 2015 Mar 10;6(7):5072-87.
Title: Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop.
Author: Yang, Zhengyan|Guo, Liang|Liu, Dan|Sun, Limin|Chen, Hongyu|Deng, Que|Liu, Yanjun|Yu, Ming|Ma, Yuanfang|Guo, Ning|Shi, Ming
PMID: 25669984
Journal: Chin Med J (Engl). 2015 Feb 20;128(4):545-9.
Title: G-protein coupled receptor 34 knockdown impairs the proliferation and migration of HGC-27 gastric cancer cells in vitro.
Author: Jin, Zhong-Tian|Li, Kun|Li, Mei|Ren, Zhi-Gang|Wang, Fu-Shun|Zhu, Ji-Ye|Leng, Xi-Sheng|Yu, Wei-Dong
PMID: 25673461
Journal: J Pathol. 2015 Jun;236(2):175-85.
Title: ACK1 promotes gastric cancer epithelial-mesenchymal transition and metastasis through AKT-POU2F1-ECD signalling.
Author: Xu, Song-Hui|Huang, Jin-Zhou|Xu, Man-Li|Yu, Guangchuang|Yin, Xing-Feng|Chen, De|Yan, Guang-Rong
PMID: 25678401
Journal: Sci Rep. 2015 Feb 16;5:8473.
Title: Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer.
Author: Tan, Juan|Yu, Chen-Yang|Wang, Zhen-Hua|Chen, Hao-Yan|Guan, Jian|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 25683757
Journal: Cell Signal. 2015 Jun;27(6):1075-86.
Title: Upregulated, 7q21-22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer.
Author: Tamilzhalagan, Sembulingam|Muthuswami, Muthulakshmi|Periasamy, Jayaprakash|Lee, Ming Hui|Rha, Sun Young|Tan, Patrick|Ganesan, Kumaresan
PMID: 25697906
Journal: Med Oncol. 2015 Mar;32(3):76.
Title: C23 protein meditates bone morphogenetic protein-2-mediated EMT via up-regulation of Erk1/2 and Akt in gastric cancer.
Author: Yang, Yonggang|Yang, Chunyan|Zhang, Jianping
PMID: 25698539
Journal: Tumour Biol. 2015 Jul;36(7):5607-15.
Title: Celecoxib sensitizes gastric cancer to rapamycin via inhibition of the Cbl-b-regulated PI3K/Akt pathway.
Author: Cao, Yubo|Qu, Jinglei|Li, Ce|Yang, Dan|Hou, Kezuo|Zheng, Huachuan|Liu, Yunpeng|Qu, Xiujuan
PMID: 25701378
Journal: Int J Biol Macromol. 2015 May;76:242-53.
Title: Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis.
Author: Zan, Xinyi|Cui, Fengjie|Li, Yunhong|Yang, Yan|Wu, Di|Sun, Wenjing|Ping, Lifeng
PMID: 25703932
Journal: Virchows Arch. 2015 May;466(5):525-32.
Title: TRIM24 is upregulated in human gastric cancer and promotes gastric cancer cell growth and chemoresistance.
Author: Miao, Zhi-Feng|Wang, Zhen-Ning|Zhao, Ting-Ting|Xu, Ying-Ying|Wu, Jian-Hua|Liu, Xing-Yu|Xu, Hao|You, Yi|Xu, Hui-Mian
PMID: 25724180
Journal: Cancer Lett. 2015 May 28;361(1):57-66.
Title: Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis.
Author: Hao, Ning-Bo|Tang, Bo|Wang, Guo-Zheng|Xie, Rui|Hu, Chang-Jiang|Wang, Su-Min|Wu, Yu-Yun|Liu, En|Xie, Xia|Yang, Shi-Ming
PMID: 25727320
Journal: World J Gastroenterol. 2015 Feb 28;21(8):2323-35.
Title: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation.
Author: Cheng, Ya-Jun|Zhu, Zhen-Xin|Zhou, Jian-Sheng|Hu, Zun-Qi|Zhang, Jian-Peng|Cai, Qing-Ping|Wang, Liang-Hua
PMID: 25741138
Journal: Biochem Biophys Res Commun. 2015 Apr 17;459(4):629-35.
Title: The role of microRNA-1274a in the tumorigenesis of gastric cancer: accelerating cancer cell proliferation and migration via directly targeting FOXO4.
Author: Wang, Guo-Jun|Liu, Guang-Hui|Ye, Yan-Wei|Fu, Yang|Zhang, Xie-Fu
PMID: 25753202
Journal: World J Gastroenterol. 2015 Mar 7;21(9):2605-13.
Title: Role of periostin and its antagonist PNDA-3 in gastric cancer metastasis.
Author: Liu, Guo-Xiao|Xi, Hong-Qing|Sun, Xiao-Yan|Wei, Bo
PMID: 25759527
Journal: Drug Des Devel Ther. 2015 Mar 2;9:1293-318.
Title: Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and N
Author: Yuan, Chun-Xiu|Zhou, Zhi-Wei|Yang, Yin-Xue|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Tianxing|Pan, Si-Yuan|Chen, Xiao-Wu|Zhou, Shu-Feng
PMID: 25767376
Journal: Dig Dis Sci. 2015 Aug;60(8):2338-45.
Title: Hyperglycemia Promotes Human Gastric Carcinoma Progression via Aquaporin 3.
Author: Zhou, Yangchun|Wang, Yao|Wang, Shoulin|Shen, Lizong
PMID: 25777259
Journal: Med Oncol. 2015 Apr;32(4):133.
Title: Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin.
Author: Zhu, Xingchao|Zhang, Kaiguang|Wang, Qiaomin|Chen, Si|Gou, Yawen|Cui, Yufang|Li, Qin
PMID: 25796504
Journal: Histopathology. 2015 Nov;67(5):677-88.
Title: Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients.
Author: Min, Lingqiang|Ruan, Yuanyuan|Shen, Zhenbin|Jia, Dongwei|Wang, Xuefei|Zhao, Junjie|Sun, Yihong|Gu, Jianxin
PMID: 25809930
Journal: Cancer. 2015 Jul 1;121(13):2193-7.
Title: Phase 2 study of MK-2206, an allosteric inhibitor of AKT, as second-line therapy for advanced gastric and gastroesophageal junction cancer: A SWOG cooperative group trial (S1005).
Author: Ramanathan, Ramesh K|McDonough, Shannon L|Kennecke, Hagen F|Iqbal, Syma|Baranda, Joaquina C|Seery, Tara E|Lim, Howard J|Hezel, Aram F|Vaccaro, Gina M|Blanke, Charles D
PMID: 25827820
Journal: Oncotarget. 2015 Apr 10;6(10):8323-38.
Title: Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients.
Author: Li, Jian|Deng, Zhijuan|Wang, Zhu|Wang, Dong|Zhang, Longjuan|Su, Qiao|Lai, Yingrong|Li, Bin|Luo, Zexing|Chen, Xu|Chen, Yu|Huang, Xiaohui|Ma, Jieyi|Wang, Wenjian|Bi, Jiong|Guan, Xinyuan
PMID: 25831050
Journal: Nutr Cancer. 2015;67(3):523-31.
Title: Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells.
Author: Yi, Tingting|Zhuang, Luhua|Song, Gang|Zhang, Bing|Li, Guideng|Hu, Tianhui
PMID: 25837881
Journal: J Cancer Prev. 2015 Mar;20(1):50-6.
Title: Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells.
Author: Lu, Jing Nan|Lee, Won Sup|Nagappan, Arulkumar|Chang, Seong-Hwan|Choi, Yung Hyun|Kim, Hye Jung|Kim, Gon Sup|Ryu, Chung Ho|Shin, Sung Chul|Jung, Jin-Myung|Hong, Soon Chan
PMID: 25853103
Journal: Int J Oncol. 2015;46(6):2355-63.
Title: Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells.
Author: Tian, Feng|Ding, Ding|Li, Dandan
PMID: 25872479
Journal: Chin Med J (Engl). 2015 Apr 20;128(8):1065-71.
Title: CDX2 inhibits invasion and migration of gastric cancer cells by phosphatase and tensin homologue deleted from chromosome 10/Akt signaling pathway.
Author: Liu, Yong-Qiang|Bai, Zhi-Gang|Ma, Xue-Mei|Zhang, Zhong-Tao
PMID: 25881601
Journal: BMC Cancer. 2015 Mar 7;15:103.
Title: Lymphangiogenesis in gastric cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis.
Author: Chen, Hongxia|Guan, Runnian|Lei, Yupeng|Chen, Jianyong|Ge, Qi|Zhang, Xiaoshen|Dou, Ruoxu|Chen, Hongyuan|Liu, Hao|Qi, Xiaolong|Zhou, Xiaodong|Chen, Changyan
PMID: 25884175
Journal: BMC Complement Altern Med. 2015 Feb 26;15:33.
Title: Antitumor effect and apoptosis induction of Alocasia cucullata (Lour.) G. Don in human gastric cancer cells in vitro and in vivo.
Author: Wei, Peng|Zhiyu, Chen|Xu, Tang|Xiangwei, Zheng
PMID: 25888009
Journal: Mol Cancer. 2015 Mar 24;14:64.
Title: The role of TGFBI (betaig-H3) in gastrointestinal tract tumorigenesis.
Author: Han, Bing|Cai, Haolei|Chen, Ying|Hu, Bing|Luo, Hongyu|Wu, Yulian|Wu, Jiangping
PMID: 25889002
Journal: Int Immunopharmacol. 2015 Jun;26(2):277-85.
Title: Role of mimic of manganese superoxide dismutase in proliferation and apoptosis of gastric carcinoma BGC-823 cells in vitro and in vivo.
Author: Wang, Yan-Hong|Zhou, Zu-Bang|Guo, Chang-An|Zhai, Jing|Qi, Fa-Mei|Li, Hong-Ling
PMID: 25889634
Journal: Tumour Biol. 2015 Sep;36(9):7233-41.
Title: A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer.
Author: Fan, Lei|Li, Wulan|Ying, Shilong|Shi, Lingyi|Wang, Zhe|Chen, Gaozhi|Ye, Hui|Wu, Xiaoping|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 25894376
Journal: Oncotarget. 2015;6(12):9794-806.
Title: Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer.
Author: Lv, Bin|Song, Chunhua|Wu, Lijun|Zhang, Qi|Hou, Daisen|Chen, Ping|Yu, Shunji|Wang, Zhicheng|Chu, Yiwei|Zhang, Jun|Yang, Dongqin|Liu, Jie
PMID: 25909166
Journal: World J Gastroenterol. 2015 Apr 21;21(15):4564-73.
Title: MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer.
Author: Lu, Wei-Dong|Zuo, Yun|Xu, Zhen|Zhang, Min
PMID: 25914465
Journal: Hepatogastroenterology. 2015 Mar-Apr;62(138):540-5.
Title: Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer.
Author: Ikeo, Koichi|Oshima, Tadayuki|Shan, Jing|Matsui, Hirofumi|Tomita, Toshihiko|Fukui, Hirokazu|Watari, Jiro|Miwa, Hiroto
PMID: 25916097
Journal: Int J Immunopathol Pharmacol. 2015 Jun;28(2):194-200.
Title: Blockade of CXCR6 reduces invasive potential of gastric cancer cells through inhibition of AKT signaling.
Author: Li, Ya|Fu, Li-Xia|Zhu, Wan-Lin|Shi, Hua|Chen, Li-Jian|Ye, Bin
PMID: 25921630
Journal: J Exp Clin Cancer Res. 2015 Apr 17;34:35.
Title: MicroRNA-144 inhibits the metastasis of gastric cancer by targeting MET expression.
Author: Liu, Jun|Xue, Hui|Zhang, Jianjun|Suo, Tao|Xiang, Yijin|Zhang, Wen|Ma, Jun|Cai, Dingfang|Gu, Xixi
PMID: 25927670
Journal: Mol Med Rep. 2015 Aug;12(2):2926-32.
Title: Secreted protein acidic and rich in cysteine antagonizes bufalin-induced apoptosis in gastric cancer cells.
Author: Li, Aodi|Qu, Xiujuan|Li, Zhi|Qu, Jinglei|Song, Na|Ma, Yanju|Liu, Yunpeng
PMID: 25936899
Journal: Oncotarget. 2015 Jun 20;6(17):15222-34.
Title: MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling.
Author: Huang, Na|Wu, Zhenzhen|Lin, Li|Zhou, Minyu|Wang, Lin|Ma, Huanrong|Xia, Jianling|Bin, Jianping|Liao, Yulin|Liao, Wangjun
PMID: 25945841
Journal: Oncotarget. 2015 Jun 30;6(18):16168-82.
Title: Intelectin 1 suppresses tumor progression and is associated with improved survival in gastric cancer.
Author: Li, Dan|Zhao, Xiang|Xiao, Yong|Mei, Hong|Pu, Jiarui|Xiang, Xuan|Jiao, Wanju|Song, Huajie|Qu, Hongxia|Huang, Kai|Zheng, Liduan|Tong, Qiangsong
PMID: 25965823
Journal: Oncotarget. 2015 Jul 20;6(20):17911-22.
Title: Loss of TFF1 promotes Helicobacter pylori-induced beta-catenin activation and gastric tumorigenesis.
Author: Soutto, Mohammed|Romero-Gallo, Judith|Krishna, Uma|Piazuelo, M Blanca|Washington, M Kay|Belkhiri, Abbes|Peek, Richard M Jr|El-Rifai, Wael
PMID: 25980439
Journal: Oncotarget. 2015 Aug 14;6(23):19552-79.
Title: ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression.
Author: Gou, Wen-feng|Shen, Dao-fu|Yang, Xue-feng|Zhao, Shuang|Liu, Yun-peng|Sun, Hong-zhi|Su, Rong-Jian|Luo, Jun-sheng|Zheng, Hua-chuan
PMID: 25980581
Journal: Sci Rep. 2015 May 18;5:10336.
Title: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways.
Author: Hao, Wenjin|Yuan, Xuan|Yu, Lina|Gao, Caixia|Sun, Xiling|Wang, Dong|Zheng, Qiusheng
PMID: 25981581
Journal: J Exp Clin Cancer Res. 2015 May 20;34:52.
Title: Gastric cancer-derived mesenchymal stem cells prompt gastric cancer progression through secretion of interleukin-8.
Author: Li, Wei|Zhou, Ying|Yang, Jin|Zhang, Xu|Zhang, Huanhuan|Zhang, Ting|Zhao, Shaolin|Zheng, Ping|Huo, Juan|Wu, Huiyi
PMID: 25986392
Journal: Tumour Biol. 2015 Nov;36(11):8379-87.
Title: The de-ubiquitinase UCHL1 promotes gastric cancer metastasis via the Akt and Erk1/2 pathways.
Author: Gu, Yu-yu|Yang, Mei|Zhao, Mei|Luo, Qing|Yang, Lin|Peng, Hua|Wang, Jia|Huang, Sheng-kai|Zheng, Zhao-xu|Yuan, Xing-hua|Liu, Ping|Huang, Chang-zhi
PMID: 26018507
Journal: Oncotarget. 2015 Aug 21;6(24):20449-65.
Title: Epigenetically downregulated Semaphorin 3E contributes to gastric cancer.
Author: Chen, Hui|Xie, Guo-Hua|Wang, Wei-Wei|Yuan, Xiang-Liang|Xing, Wen-Ming|Liu, Hong-Jing|Chen, Jin|Dou, Min|Shen, Li-Song
PMID: 26036259
Journal: Cytokine. 2015 Dec;76(2):163-169.
Title: CrkL meditates CCL20/CCR6-induced EMT in gastric cancer.
Author: Han, Gang|Wu, Dawei|Yang, Yongan|Li, Zhiyun|Zhang, Jiapin|Li, Chengjun
PMID: 26044596
Journal: Cancer Res. 2015 Aug 1;75(15):3087-97.
Title: KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78.
Author: Kang, Jin Muk|Park, Sujin|Kim, Staci Jakyong|Kim, Hyojung|Lee, Bona|Kim, Junil|Park, Jinah|Kim, Shin Tae|Yang, Han-Kwang|Kim, Woo Ho|Kim, Seong-Jin
PMID: 26045166
Journal: Am J Cancer Res. 2015 Mar 15;5(4):1423-34. eCollection 2015.
Title: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling.
Author: Chen, Guangxia|Feng, Wan|Zhang, Shu|Bian, Kangqi|Yang, Yan|Fang, Cheng|Chen, Min|Yang, Jun|Zou, Xiaoping
PMID: 26101707
Journal: Sci Rep. 2015 Jun 25;5:11634.
Title: Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance.
Author: Zuo, Qiang|Liu, Jing|Zhang, Jingwen|Wu, Mengwan|Guo, Lihong|Liao, Wangjun
PMID: 26108989
Journal: World J Gastroenterol. 2015 Jun 21;21(23):7197-207.
Title: Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling.
Author: Zheng, Yong-Bin|Xiao, Gao-Chun|Tong, Shi-Lun|Ding, Yu|Wang, Qiu-Shuang|Li, Sheng-Bo|Hao, Zhi-Nan
PMID: 26109806
Journal: Molecules. 2015 Jun 22;20(6):11524-34.
Title: Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro.
Author: Zhang, Jian-Ye|Lin, Min-Ting|Zhou, Meng-Jia|Yi, Tao|Tang, Yi-Na|Tang, Si-Li|Yang, Zhi-Jun|Zhao, Zhong-Zhen|Chen, Hu-Biao
PMID: 26111180
Journal: Clin Exp Metastasis. 2015 Aug;32(6):593-603.
Title: Targeting Notch signaling by gamma-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer.
Author: Lee, Hyun-Woo|Kim, Seok-Jun|Choi, Il Ju|Song, Jaewhan|Chun, Kyung-Hee
PMID: 26134677
Journal: Tumour Biol. 2015 Dec;36(12):9537-44.
Title: Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil.
Author: Chen, Wei-Yu|Huang, Chien-Yu|Cheng, Wan-Li|Hung, Chin-Sheng|Huang, Ming-Te|Tai, Cheng-Jeng|Liu, Yen-Nien|Chen, Chi-Long|Chang, Yu-Jia
PMID: 26136123
Journal: Biochem Biophys Res Commun. 2015 Aug 21;464(2):534-40.
Title: Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer.
Author: Bian, Yuhai|Wang, Zhengshi|Xu, Jia|Zhao, Wenyi|Cao, Hui|Zhang, Zhigang
PMID: 26159923
Journal: Oncol Rep. 2015 Sep;34(3):1517-25.
Title: Flavonoids isolated from Citrus platymamma induce mitochondrial-dependent apoptosis in AGS cells by modulation of the PI3K/AKT and MAPK pathways.
Author: Lee, Ho Jeong|Nagappan, Arulkumar|Park, Hyeon Soo|Hong, Gyeong Eun|Yumnam, Silvia|Raha, Suchismita|Saralamma, Venu Venkatarame Gowda|Lee, Won Sup|Kim, Eun Hee|Kim, Gon Sup
PMID: 26165353
Journal: PLoS One. 2015 Jul 13;10(7):e0132829.
Title: Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation.
Author: Hou, Liying|Li, Yuze|Song, Huacui|Zhang, Zhihong|Sun, Yanpei|Zhang, Xuguang|Wu, Kun
PMID: 26168048
Journal: Oncol Lett. 2015 Jul;10(1):502-508.
Title: Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells.
Author: Wang, Ying|Chen, Yongchang|Wu, Min|Lan, Ting|Wu, Yan|Li, Yueying|Qian, Hai
PMID: 26171059
Journal: PLoS One. 2015 Jul 17;10(7):e0128751.
Title: MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway.
Author: Zheng, Zhiqiang|Yan, Dongsheng|Chen, Xiaoyan|Huang, He|Chen, Ke|Li, Guangjing|Zhou, Linglin|Zheng, Dandan|Tu, LiLi|Dong, Xiang Da
PMID: 26186594
Journal: Int J Oncol. 2015 Sep;47(3):1061-9.
Title: Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells.
Author: Raha, Suchismita|Yumnam, Silvia|Hong, Gyeong Eun|Lee, Ho Jeong|Saralamma, Venu Venkatarame Gowda|Park, Hyeon-Soo|Heo, Jeong Doo|Lee, Sang Joon|Kim, Eun Hee|Kim, Jin-A|Kim, Gon Sup
PMID: 26201693
Journal: Drug Des Devel Ther. 2015 Jul 16;9:3607-16.
Title: Downregulation of miR203 induces overexpression of PIK3CA and predicts poor prognosis of gastric cancer patients.
Author: Liang, Min|Shi, Boyun|Liu, Jifang|He, Lu|Yi, Gao|Zhou, Lin|Yu, Guifang|Zhou, Xinke
PMID: 26213461
Journal: PLoS One. 2015 Jul 30;10(7):e0134122.
Title: Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the beta-Catenin Pathway.
Author: Wu, Ming-Hsun|Lee, Wei-Jiunn|Hua, Kuo-Tai|Kuo, Min-Liang|Lin, Ming-Tsan
PMID: 26226629
Journal: Mol Med Rep. 2015 Oct;12(4):5601.
Title: [Retraction] Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.
Author:
PMID: 26238072
Journal: Oncol Rep. 2015 Oct;34(4):2179-87.
Title: HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-kappaB activation.
Author: Koh, Sung Ae|Lee, Kyung Hee
PMID: 26259977
Journal: Oncotarget. 2015 Sep 22;6(28):24750-79.
Title: Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy.
Author: Riquelme, Ismael|Saavedra, Kathleen|Espinoza, Jaime A|Weber, Helga|Garcia, Patricia|Nervi, Bruno|Garrido, Marcelo|Corvalan, Alejandro H|Roa, Juan Carlos|Bizama, Carolina
PMID: 26267324
Journal: Clin Cancer Res. 2015 Dec 15;21(24):5519-31.
Title: Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas.
Author: Leto, Simonetta M|Sassi, Francesco|Catalano, Irene|Torri, Valter|Migliardi, Giorgia|Zanella, Eugenia R|Throsby, Mark|Bertotti, Andrea|Trusolino, Livio
PMID: 26296355
Journal: PLoS Comput Biol. 2015 Aug 28;11(8):e1004426.
Title: Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling.
Author: Flobak, Asmund|Baudot, Anais|Remy, Elisabeth|Thommesen, Liv|Thieffry, Denis|Kuiper, Martin|Laegreid, Astrid
PMID: 26317215
Journal: PLoS One. 2015 Aug 28;10(8):e0136447.
Title: Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
Author: Piao, Ying|Li, Ying|Xu, Qian|Liu, Jing-wei|Xing, Cheng-zhong|Xie, Xiao-dong|Yuan, Yuan
PMID: 26317520
Journal: Int J Oncol. 2015 Nov;47(5):1725-34.
Title: Fra-1 is upregulated in gastric cancer tissues and affects the PI3K/Akt and p53 signaling pathway in gastric cancer.
Author: He, Junyu|Zhu, Guangchao|Gao, Lu|Chen, Pan|Long, Yuehua|Liao, Shan|Yi, Hong|Yi, Wei|Pei, Zhen|Wu, Minghua|Li, Xiaoling|Xiang, Juanjuan|Peng, Shuping|Ma, Jian|Zhou, Ming|Xiong, Wei|Zeng, Zhaoyang|Xiang, Bo|Tang, Ke|Cao, Li|Li, Guiyuan|Zhou, Yanhong
PMID: 26330014
Journal: Int J Nanomedicine. 2015 Aug 25;10 Spec Iss:143-53.
Title: Anticancer activities of self-assembled molecular bowls containing a phenanthrene-based donor and Ru(II) acceptors.
Author: Kim, Inhye|Song, Young Ho|Singh, Nem|Jeong, Yong Joon|Kwon, Jung Eun|Kim, Hyunuk|Cho, Young Mi|Kang, Se Chan|Chi, Ki-Whan
PMID: 26347134
Journal: Evid Based Complement Alternat Med. 2015;2015:402385.
Title: Auraptene, a Major Compound of Supercritical Fluid Extract of Phalsak (Citrus Hassaku Hort ex Tanaka), Induces Apoptosis through the Suppression of mTOR Pathways in Human Gastric Cancer SNU-1 Cells.
Author: Moon, Jeong Yong|Kim, Hyeonji|Cho, Somi Kim
PMID: 26351512
Journal: Cell Biochem Funct. 2015 Oct;33(7):451-61.
Title: ODAM inhibits RhoA-dependent invasion in breast cancer.
Author: Lee, Hye-Kyung|Choung, Han-Wool|Yang, Young-Il|Yoon, Hye-Jung|Park, In Ae|Park, Joo-Cheol
PMID: 26358398
Journal: Onco Targets Ther. 2015 Sep 1;8:2427-33.
Title: The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis.
Author: Ying, Jieer|Xu, Qi|Liu, Bixia|Zhang, Gu|Chen, Lei|Pan, Hongming
PMID: 26366097
Journal: Int J Oncol. 2015 Nov;47(5):1801-10.
Title: miR-125a regulates angiogenesis of gastric cancer by targeting vascular endothelial growth factor A.
Author: Dai, Jun|Wang, Jinyu|Yang, Lili|Xiao, Ying|Ruan, Qiurong
PMID: 26398444
Journal: Int J Oncol. 2015 Nov;47(5):1617-26.
Title: The JAK/STAT signaling cascade in gastric carcinoma (Review).
Author: Khanna, Puja|Chua, Pei Jou|Bay, Boon Huat|Baeg, Gyeong Hun
PMID: 26398764
Journal: World J Gastroenterol. 2015 Sep 28;21(36):10385-99.
Title: Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway.
Author: Yang, Zhi-Ping|Zhao, Yan|Huang, Fang|Chen, Jie|Yao, Ya-Hong|Li, Jun|Wu, Xiao-Nan
PMID: 26420965
Journal: Mol Med Rep. 2015 Dec;12(6):8201-8.
Title: DNA methylation inhibitor, decitabine, promotes MGC803 gastric cancer cell migration and invasion via the upregulation of NEDD41.
Author: Li, Dong|Xu, Chun-Yan|Cui, Rong-Jun|Tang, Jie-Bing|Sun, Hui|Yang, Zheng-Kai|Bu, Jing-Yi|Lin, Ping|Huang, Ning|Du, Yan-Dan|Yu, Xiao-Guang
PMID: 26458406
Journal: Zhonghua Zhong Liu Za Zhi. 2015 Jun;37(6):404-11.
Title: [Molecular mechanism of cisplatin to enhance the ability of TRAIL in reversing multidrug resistance in gastric cancer cells].
Author: Zhu, Xingchao|Zhang, Kaiguang|Wang, Qiaomin|Chen, Si|Gou, Yawen|Cui, Yufang|Li, Qin
PMID: 26463141
Journal: BMC Microbiol. 2015 Oct 21;15:222.
Title: Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1).
Author: King, Charles C|Obonyo, Marygorret
PMID: 26487493
Journal: World J Gastroenterol. 2015 Oct 21;21(39):10956-81.
Title: Dysregulation of non-coding RNAs in gastric cancer.
Author: Yang, Qing|Zhang, Ren-Wen|Sui, Peng-Cheng|He, Hai-Tao|Ding, Lei
PMID: 26494954
Journal: Int J Oncol. 2015 Dec;47(6):2226-32.
Title: Sulforaphane inhibits hypoxia-induced HIF-1alpha and VEGF expression and migration of human colon cancer cells.
Author: Kim, Dong Hwan|Sung, Bokyung|Kang, Yong Jung|Hwang, Seong Yeon|Kim, Min Jeong|Yoon, Jeong-Hyun|Im, Eunok|Kim, Nam Deuk
PMID: 26498863
Journal: J Exp Clin Cancer Res. 2015 Nov 4;34:135.
Title: Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway.
Author: Zhou, Jianping|Zhi, Xiaofei|Wang, Linjun|Wang, Weizhi|Li, Zheng|Tang, Jie|Wang, Jiwei|Zhang, Qun|Xu, Zekuan
PMID: 26538117
Journal: Biomed Res Int. 2015;2015:761501.
Title: Helicobacter pylori CagA Suppresses Apoptosis through Activation of AKT in a Nontransformed Epithelial Cell Model of Glandular Acini Formation.
Author: Vallejo-Flores, Gabriela|Torres, Javier|Sandoval-Montes, Claudia|Arevalo-Romero, Haruki|Meza, Isaura|Camorlinga-Ponce, Margarita|Torres-Morales, Julian|Chavez-Rueda, Adriana Karina|Legorreta-Haquet, Maria Victoria|Fuentes-Panana, Ezequiel M
PMID: 26557697
Journal: BMC Cancer. 2015 Nov 11;15:894.
Title: Dual PI3K/mTOR inhibitor BEZ235 exerts extensive antitumor activity in HER2-positive gastric cancer.
Author: Zhu, Yan|Tian, Tiantian|Zou, Jianling|Wang, Qiwei|Li, Zhongwu|Li, Yanyan|Liu, Xijuan|Dong, Bin|Li, Na|Gao, Jing|Shen, Lin
PMID: 26560145
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2015 Oct;37(5):514-9.
Title: [miR-29b Reduces Cisplatin Resistance of Gastric Cancer Cell by Targeting PI3K/Akt Pathway].
Author: Chen, Dian-dian|Feng, Lin-chun|Ye, Rui|He, Yu-qi|Wang, Ya-di
PMID: 26564501
Journal: World J Gastroenterol. 2015 Nov 21;21(43):12261-73.
Title: Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
Author: Singh, Shikha Satendra|Yap, Wei Ney|Arfuso, Frank|Kar, Shreya|Wang, Chao|Cai, Wanpei|Dharmarajan, Arunasalam M|Sethi, Gautam|Kumar, Alan Prem
PMID: 26604635
Journal: BMC Cancer. 2015 Nov 25;15:935.
Title: Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis.
Author: Goswami, Sudeshna|Sharma-Walia, Neelam
PMID: 26608463
Journal: Exp Ther Med. 2015 Sep;10(3):1212-1218.
Title: Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway.
Author: Xie, Hua-Xia|Xu, Zhi-Yuan|Tang, Jia-Ning|DU, Yi-An|Huang, Ling|Yu, Peng-Fei|Cheng, Xiang-Dong
PMID: 26622467
Journal: Oncol Lett. 2015 Aug;10(2):607-611.
Title: AKT plays a crucial role in gastric cancer.
Author: Sasaki, Takamitsu|Yamashita, Yuichi|Kuniyasu, Hiroki
PMID: 26622541
Journal: Oncol Lett. 2015 Dec;10(6):3732-3736.
Title: Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand.
Author: Chen, Hui|Li, Liang-Qing|Pan, Dun
PMID: 26788199
Journal: J Gastroenterol. 2016 Mar;51(3):230-40.
Title: Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt.
Author: Ye, Yan|Ge, Yan Mei|Xiao, Miao Miao|Guo, Li Mei|Li, Qun|Hao, Ji Qing|Da, Jie|Hu, Wang Lai|Zhang, Xu Dong|Xu, Jiegou|Zhang, Lin Jie
PMID: 26201869
Journal: Tumour Biol. 2016 Jan;37(1):1091-6.
Title: The involvement of survivin in insulin-like growth factor 1-induced epithelial-mesenchymal transition in gastric cancer.
Author: Li, Chengjun|Li, Jinbao|Wu, Dawei|Han, Gang
PMID: 26271669
Journal: Biotechnol Appl Biochem. 2016 Nov;63(6):841-851.
Title: Potential role of O-GlcNAcylation and involvement of PI3K/Akt1 pathway in the expression of oncogenic phenotypes of gastric cancer cells in vitro.
Author: Zhang, Nuobei|Chen, Xin
PMID: 26333304
Journal: Cell Oncol (Dordr). 2016 Feb;39(1):23-33.
Title: miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
Author: Riquelme, Ismael|Tapia, Oscar|Leal, Pamela|Sandoval, Alejandra|Varga, Matthew G|Letelier, Pablo|Buchegger, Kurt|Bizama, Carolina|Espinoza, Jaime A|Peek, Richard M|Araya, Juan Carlos|Roa, Juan Carlos
PMID: 26458815
Journal: Int J Oncol. 2016 Jan;48(1):199-206.
Title: TIPE2 functions as a metastasis suppressor via negatively regulating beta-catenin through activating GSK3beta in gastric cancer.
Author: Wu, Jie|Zhang, Haitao|Xu, Chun|Xu, Hong|Zhou, Xiumin|Xie, Yufeng|Tao, Min
PMID: 26530498
Journal: Oncol Rep. 2016 Jan;35(1):472-8.
Title: Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway.
Author: Jing, Xiaoping|Cheng, Weiwei|Wang, Shiying|Li, Pin|He, Li
PMID: 26530632
Journal: Anticancer Drugs. 2016 Mar;27(3):164-72.
Title: Peptidomimetic suppresses proliferation and invasion of gastric cancer cells by fibroblast growth factor 2 signaling cascade blockage.
Author: Li, Wulan|Du, Xiaojing|Chen, Qiuxiang|Kang, Yanting|Xu, Chaochao|Fan, Lei|Ye, Hui|Ying, Shilong|Shi, Lingyi|Jin, Rong|Wu, Jianzhang|Liang, Guang|Li, Xiaokun
PMID: 26556626
Journal: Oncotarget. 2016 Jan 26;7(4):3791-805.
Title: Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway.
Author: Wang, Lan|Ouyang, Fei|Liu, Xiaobo|Wu, Shu|Wu, Hong-Mei|Xu, Yuandong|Wang, Bin|Zhu, Jinrong|Xu, Xuehu|Zhang, Liang
PMID: 26565812
Journal: J Drug Target. 2016;24(6):557-65.
Title: Smilax glabra Roxb targets Akt(p-Thr308) and inhibits Akt-mediated signaling pathways in SGC7901 cells.
Author: Hao, Guangzhi|Zheng, Jun|Huo, Rentao|Li, Jingchen|Wen, Kai|Zhang, Yinsong|Liang, Guobiao
PMID: 26607178
Journal: Pathol Res Pract. 2016 Jan;212(1):31-7.
Title: TRAF6 promotes the invasion and metastasis and predicts a poor prognosis in gastric cancer.
Author: Han, Fei|Zhang, Long|Qiu, Weizhe|Yi, Xianghua
PMID: 26627263
Journal: J Recept Signal Transduct Res. 2016 Oct;36(5):471-7.
Title: 5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone, a polymethoxyflavone, exerts antitumor effect on PI3K/Akt signaling pathway in human gastric cancer cell BGC-7901.
Author: Wang, Xinjian|Xia, Min
PMID: 26671739
Journal: J Pathol. 2016 Mar;238(4):562-70.
Title: HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Author: Richman, Susan D|Southward, Katie|Chambers, Philip|Cross, Debra|Barrett, Jennifer|Hemmings, Gemma|Taylor, Morag|Wood, Henry|Hutchins, Gordon|Foster, Joseph M|Oumie, Assa|Spink, Karen G|Brown, Sarah R|Jones, Marc|Kerr, David|Handley, Kelly|Gray, Richard|Se
PMID: 26690310
Journal: Oncotarget. 2016 Feb 2;7(5):6201-20.
Title: Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers.
Author: Fang, Wen-Liang|Huang, Kuo-Hung|Lan, Yuan-Tzu|Lin, Chien-Hsing|Chang, Shih-Ching|Chen, Ming-Huang|Chao, Yee|Lin, Wen-Chang|Lo, Su-Shun|Li, Anna Fen-Yau|Wu, Chew-Wun|Chiou, Shih-Hwa|Shyr, Yi-Ming
PMID: 26701847
Journal: Oncol Rep. 2016 Feb;35(2):1101-8.
Title: Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells.
Author: Gao, Lei|Xu, Zhen|Wang, Yan|Sun, Bin|Song, Zhicheng|Yang, Bining|Liu, Xu|Lin, Yuan|Peng, Jinyong|Han, Guozhu|Wang, Shisheng|Tang, Zeyao
PMID: 26718492
Journal: Oncol Rep. 2016 Feb;35(2):1135-46.
Title: Integrated analysis of the miRNA, gene and pathway regulatory network in gastric cancer.
Author: Zhang, Haiyang|Qu, Yanjun|Duan, Jingjing|Deng, Ting|Liu, Rui|Zhang, Le|Bai, Ming|Li, Jialu|Zhou, Likun|Ning, Tao|Li, Hongli|Ge, Shaohua|Li, Hua|Ying, Guoguang|Huang, Dingzhi|Ba, Yi
PMID: 26719093
Journal: Tumour Biol. 2016 Jun;37(6):8317-25.
Title: Upregulation of microRNA-31 targeting integrin alpha5 suppresses tumor cell invasion and metastasis by indirectly regulating PI3K/AKT pathway in human gastric cancer SGC7901 cells.
Author: Zhang, Xue-Bin|Song, Lei|Wen, Hong-Juan|Bai, Xiao-Xue|Li, Zhen-Juan|Ma, Lian-Jun
PMID: 26729197
Journal: Oncotarget. 2016 Jan 26;7(4):4414-27.
Title: GNA13 as a prognostic factor and mediator of gastric cancer progression.
Author: Zhang, Jia-Xing|Yun, Miao|Xu, Yi|Chen, Jie-Wei|Weng, Hui-Wen|Zheng, Zou-San|Chen, Cui|Xie, Dan|Ye, Sheng
PMID: 26735177
Journal: Mol Cells. 2016 Mar;39(3):217-28.
Title: Substitution of Heavy Complementarity Determining Region 3 (CDR-H3) Residues Can Synergistically Enhance Functional Activity of Antibody and Its Binding Affinity to HER2 Antigen.
Author: Moon, Seung Kee|Park, So Ra|Park, Ami|Oh, Hyun Mi|Shin, Hyun Jung|Jeon, Eun Ju|Kim, Seiwhan|Park, Hyun June|Yeon, Young Joo|Yoo, Young Je
PMID: 26743905
Journal: Cancer Res. 2016 Mar 15;76(6):1517-27.
Title: Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer.
Author: Espelin, Christopher W|Leonard, Shannon C|Geretti, Elena|Wickham, Thomas J|Hendriks, Bart S
PMID: 26759238
Journal: Tumour Biol. 2016 Jul;37(7):9169-79.
Title: The proliferation impairment induced by AQP3 deficiency is the result of glycerol uptake and metabolism inhibition in gastric cancer cells.
Author: Li, Zheng|Li, Bowen|Zhang, Lei|Chen, Liang|Sun, Guangli|Zhang, Qun|Wang, Jiwei|Zhi, Xiaofei|Wang, Linjun|Xu, Zekuan|Xu, Hao
PMID: 26768614
Journal: Tumour Biol. 2016 Jul;37(7):9221-32.
Title: DCT015, a new sorafenib derivate, inhibits tumor growth and angiogenesis in gastric cancer models.
Author: Wang, Wenyan|Wang, Hui|Ni, Yingying|Yao, Zhenming|Ye, Liang|Tian, Jingwei
PMID: 26768619
Journal: Oncotarget. 2016 Mar 1;7(9):9815-31.
Title: Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer.
Author: Zhang, Xiaowei|Hua, Ruixi|Wang, Xiaofeng|Huang, Mingzhu|Gan, Lu|Wu, Zhenhua|Zhang, Jiejun|Wang, Hongqiang|Cheng, Yufan|Li, Jin|Guo, Weijian
PMID: 26769843
Journal: Neoplasma. 2016;63(2):239-45.
Title: Discovery of signature genes in gastric cancer associated with prognosis.
Author: Zhao, X|Cai, H|Wang, X|Ma, L
PMID: 26774142
Journal: Biochem Biophys Res Commun. 2016 Feb 5;470(2):350-355.
Title: Mefloquine effectively targets gastric cancer cells through phosphatase-dependent inhibition of PI3K/Akt/mTOR signaling pathway.
Author: Liu, Yanwei|Chen, Sen|Xue, Rui|Zhao, Juan|Di, Maojun
PMID: 26780727
Journal: Tumour Biol. 2016 Jul;37(7):9493-501.
Title: Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment.
Author: Tu, Chao-Chiang|Huang, Chien-Yu|Cheng, Wan-Li|Hung, Chin-Sheng|Chang, Yu-Jia|Wei, Po-Li
PMID: 26790437
Journal: Cancer Lett. 2016 Mar 28;372(2):239-50.
Title: LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway.
Author: Li, ZhiZhen|Chen, YuanYuan|Wang, XuAn|Zhang, HongChen|Zhang, Yijian|Gao, YaoHui|Weng, Mingzhe|Wang, Lei|Liang, HaiBin|Li, MaoLan|Zhang, Fei|Zhao, Shuai|Liu, Shibo|Cao, Yang|Shu, Yijun|Bao, Runfa|Zhou, Jian|Liu, Xiyong|Yan, Yun|Zhen, Lei|Dong, Qian|Liu, Yi
PMID: 26797416
Journal: BMC Cancer. 2016 Jan 22;16:35.
Title: Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells.
Author: Park, Chi Hoon|Cho, Sung Yun|Ha, Jae Du|Jung, Heejung|Kim, Hyung Rae|Lee, Chong Ock|Jang, In-Young|Chae, Chong Hak|Lee, Heung Kyoung|Choi, Sang Un
PMID: 26801760
Journal: Mol Carcinog. 2016 Dec;55(12):2236-2246.
Title: Helicobacter pylori induces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3beta in human gastric cancer cells.
Author: Ngo, Hoang-Kieu-Chi|Lee, Hee Geum|Piao, Juan-Yu|Zhong, Xiancai|Lee, Ha-Na|Han, Hyeong-Jun|Kim, Wonki|Kim, Do-Hee|Cha, Young-Nam|Na, Hye-Kyung|Surh, Young-Joon
PMID: 26808296
Journal: Oncotarget. 2016 Feb 16;7(7):8043-54.
Title: Lentivirus-mediated PLCgamma1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma.
Author: Zhang, Bingchang|Wang, Fen|Dai, Lianzhi|Cai, Heguo|Zhan, Yanyan|Gang, Song|Hu, Tianhui|Xia, Chun|Zhang, Bing
PMID: 26811493
Journal: Sci Rep. 2016 Jan 28;6:20008.
Title: A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.
Author: Wang, Meng-Yun|He, Jing|Zhu, Mei-Ling|Teng, Xiao-Yan|Li, Qiao-Xin|Sun, Meng-Hong|Wang, Xiao-Feng|Yang, Ya-Jun|Wang, Jiu-Cun|Jin, Li|Wang, Ya-Nong|Wei, Qing-Yi
PMID: 26818920
Journal: Hum Pathol. 2016 Mar;49:61-70.
Title: Various ARID1A expression patterns and their clinical significance in gastric cancers.
Author: Kim, Young-Bae|Ham, In-Hye|Hur, Hoon|Lee, Dakeun
PMID: 26826411
Journal: Biochem Biophys Res Commun. 2016 Sep 9;478(1):330-336.
Title: AT13148, a first-in-class multi-AGC kinase inhibitor, potently inhibits gastric cancer cells both in vitro and in vivo.
Author: Xi, Yu|Niu, Jianhua|Shen, Yun|Li, Dongmei|Peng, Xinyu|Wu, Xiangwei
PMID: 26828267
Journal: J Transl Med. 2016 Feb 1;14:32.
Title: CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells.
Author: Deng, Wenjie|Gu, Luo|Li, Xiaojie|Zheng, Jianchao|Zhang, Yujie|Duan, Biao|Cui, Jie|Dong, Jing|Du, Jun
PMID: 26830684
Journal: Nutr Metab (Lond). 2016 Feb 2;13:7.
Title: Leptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice.
Author: Inagaki-Ohara, Kyoko|Okamoto, Shiki|Takagi, Kazuyo|Saito, Kumiko|Arita, Seiya|Tang, Lijun|Hori, Tetsuji|Kataoka, Hiroaki|Matsumoto, Satoshi|Minokoshi, Yasuhiko
PMID: 26839577
Journal: BMC Cancer. 2016 Feb 4;16:60.
Title: Differences in TGF-beta1 signaling and clinicopathologic characteristics of histologic subtypes of gastric cancer.
Author: Pak, Kyung Ho|Kim, Dong Hoon|Kim, Hyunki|Lee, Do Hyung|Cheong, Jae-Ho
PMID: 26846663
Journal: Ann Surg Oncol. 2016 Jun;23(6):1986-92.
Title: Effect of EGFR and p-AKT Overexpression on Chromosomal Instability in Gastric Cancer.
Author: Hisamatsu, Yuichi|Oki, Eiji|Otsu, Hajime|Ando, Koji|Saeki, Hiroshi|Tokunaga, Eriko|Aishima, Shinichi|Morita, Masaru|Oda, Yoshinao|Maehara, Yoshihiko
PMID: 26847684
Journal: Oncotarget. 2016 Mar 1;7(9):9788-800.
Title: Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFkappaB pathway in gastric cancer development.
Author: Zhang, Bao-gui|Hu, Lei|Zang, Ming-de|Wang, He-xiao|Zhao, Wei|Li, Jian-fang|Su, Li-ping|Shao, Zhifeng|Zhao, Xiaodong|Zhu, Zheng-gang|Yan, Min|Liu, Bingya
PMID: 26848521
Journal: Gastroenterology. 2016 May;150(5):1183-1195.e16.
Title: C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits.
Author: Wang, Lan|Yin, Jie|Wang, Xuefei|Shao, Miaomiao|Duan, Fangfang|Wu, Weicheng|Peng, Peike|Jin, Jing|Tang, Yue|Ruan, Yuanyuan|Sun, Yihong|Gu, Jianxin
PMID: 26855187
Journal: Cancer Cell Int. 2016 Feb 12;16:5.
Title: Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells.
Author: Deng, Wenjie|Zhang, Yujie|Gu, Luo|Cui, Jie|Duan, Biao|Wang, Yueyuan|Du, Jun
PMID: 26877709
Journal: Exp Ther Med. 2016 Feb;11(2):403-408.
Title: Isobavachalcone induces the apoptosis of gastric cancer cells via inhibition of the Akt and Erk pathways.
Author: Jin, Xiaohong|Shi, Y I
PMID: 26893622
Journal: Exp Ther Med. 2016 Feb;11(2):625-630.
Title: Upregulation of microRNA-375 increases the cisplatin-sensitivity of human gastric cancer cells by regulating ERBB2.
Author: Zhou, Ning|Qu, Yanli|Xu, Chunlei|Tang, Yong
PMID: 26893657
Journal: Exp Ther Med. 2016 Feb;11(2):669-673.
Title: Enhanced anticancer effect of ABT-737 in combination with naringenin on gastric cancer cells.
Author: Zhang, Haiyang|Zhong, Xia|Zhang, Xiao|Shang, Deya|Zhou, Y I|Zhang, Chunqing
PMID: 26893664
Journal: PLoS One. 2016 Feb 24;11(2):e0149120.
Title: Nicotine Inhibits Cisplatin-Induced Apoptosis via Regulating alpha5-nAChR/AKT Signaling in Human Gastric Cancer Cells.
Author: Jia, Yanfei|Sun, Haiji|Wu, Hongqiao|Zhang, Huilin|Zhang, Xiuping|Xiao, Dongjie|Ma, Xiaoli|Wang, Yunshan
PMID: 26909550
Journal: Oncol Res. 2016;23(3):99-107.
Title: Long Noncoding RNA H19-Derived miR-675 Enhances Proliferation and Invasion via RUNX1 in Gastric Cancer Cells.
Author: Liu, Gao|Xiang, Tian|Wu, Quan-Feng|Wang, Wei-Xing
PMID: 26931432
Journal: Oncotarget. 2016 Mar 22;7(12):15150-60.
Title: An increase in galectin-3 causes cellular unresponsiveness to IFN-gamma-induced signal transduction and growth inhibition in gastric cancer cells.
Author: Tseng, Po-Chun|Chen, Chia-Ling|Shan, Yan-Shen|Lin, Chiou-Feng
PMID: 26934444
Journal: Cancer Lett. 2016 May 1;374(2):292-303.
Title: Helicobacter pylori upregulates Nanog and Oct4 via Wnt/beta-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer.
Author: Yong, Xin|Tang, Bo|Xiao, Yu-Feng|Xie, Rui|Qin, Yong|Luo, Gang|Hu, Chang-Jiang|Dong, Hui|Yang, Shi-Ming
PMID: 26940070
Journal: Oncotarget. 2016 Apr 19;7(16):21601-17.
Title: APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.
Author: Hong, Se-Hoon|Lee, Won Jae|Kim, Young Doo|Kim, Hyunjoo|Jeon, Young-Jun|Lim, Bitna|Cho, Dong-Hyung|Heo, Won Do|Yang, Doo-Hyun|Kim, Chan-Young|Yang, Han-Kwang|Yang, Jin Kuk|Jung, Yong-Keun
PMID: 26942872
Journal: J Biosci. 2016 Mar;41(1):77-85.
Title: MiR-128b is down-regulated in gastric cancer and negatively regulates tumour cell viability by targeting PDK1/Akt/NF-kappaB axis.
Author: Zhang, Ling|Lei, Jun|Fang, Zi-Ling|Xiong, Jian-Ping
PMID: 26949090
Journal: Tumour Biol. 2016 Aug;37(8):11365-74.
Title: Naringenin inhibits proliferation, migration, and invasion as well as induces apoptosis of gastric cancer SGC7901 cell line by downregulation of AKT pathway.
Author: Bao, Lei|Liu, Feng|Guo, Huai-Bin|Li, Yong|Tan, Bi-Bo|Zhang, Wan-Xing|Peng, Yan-Hui
PMID: 26960693
Journal: Oncotarget. 2016 Apr 19;7(16):21799-811.
Title: Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.
Author: Lin, Sheng-Yi|Lee, Yue-Xun|Yu, Sung-Liang|Chang, Gee-Chen|Chen, Jeremy J W
PMID: 26967563
Journal: Cell Biochem Funct. 2016 Apr;34(3):173-80.
Title: PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways.
Author: Akrami, Hassan|Mahmoodi, Fatemeh|Havasi, Somaye|Sharifi, Amene
PMID: 26968576
Journal: J Gastroenterol Hepatol. 2016 Oct;31(10):1717-1726.
Title: The roles of HOXB7 in promoting migration, invasion, and anti-apoptosis in gastric cancer.
Author: Joo, Moon Kyung|Park, Jong-Jae|Yoo, Hyo Soon|Lee, Beom Jae|Chun, Hoon Jai|Lee, Sang Woo|Bak, Young-Tae
PMID: 26968988
Journal: J Exp Clin Cancer Res. 2016 Mar 15;35:47.
Title: MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling.
Author: Chu, Shao-Jun|Wang, Ge|Zhang, Peng-Fei|Zhang, Rui|Huang, Yan-Xia|Lu, Yun-Min|Da, Wei|Sun, Qun|Zhang, Jing|Zhu, Jin-Shui
PMID: 26980572
Journal: Int J Oncol. 2016 May;48(5):2184-96.
Title: CXCR1 promotes malignant behavior of gastric cancer cells in vitro and in vivo in AKT and ERK1/2 phosphorylation.
Author: Wang, Junpu|Hu, Wanming|Wu, Xiaoying|Wang, Kuansong|Yu, Jun|Luo, Baihua|Luo, Gengqiu|Wang, Weiyuan|Wang, Huiling|Li, Jinghe|Wen, Jifang
PMID: 26983663
Journal: Cancer Gene Ther. 2016 Apr;23(4):98-106.
Title: Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Author: Zhu, Y|Tao, M|Wu, J|Meng, Y|Xu, C|Tian, Y|Zhou, X|Xiang, J|Zhang, H|Xie, Y
PMID: 26987289
Journal: Cancer Res Treat. 2016 Oct;48(4):1196-1209.
Title: Overexpression of Endoplasmic Reticulum Oxidoreductin 1-alpha (ERO1L) Is Associated with Poor Prognosis of Gastric Cancer.
Author: Seol, So-Young|Kim, Chul|Lim, Jae Yun|Yoon, Sun Och|Hong, Soon Won|Kim, Jong Won|Choi, Seung Ho|Cho, Jae Yong
PMID: 26987398
Journal: Oncol Lett. 2016 Mar;11(3):1745-1749.
Title: miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway.
Author: Li, N A|Wang, Weiqiang|Xu, Bin|Gong, Hongyun
PMID: 26998071
Journal: Biomed Rep. 2016 Mar;4(3):365-368.
Title: Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells.
Author: Tao, Kaixiong|Yin, Yuping|Shen, Qian|Chen, Ying|Li, Ruidong|Chang, Weilong|Bai, Jie|Liu, Weizhen|Shi, Liang|Zhang, Peng
PMID: 26998277
Journal: Oncotarget. 2016 Apr 19;7(16):22733-45.
Title: Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer.
Author: Zhang, Xiaowei|Guo, Weijian|Wang, Xiaofeng|Liu, Xinyang|Huang, Mingzhu|Gan, Lu|Cheng, Yufan|Li, Jin
PMID: 27009837
Journal: Dig Dis Sci. 2016 Aug;61(8):2272-83.
Title: DDR2 Induces Gastric Cancer Cell Activities via Activating mTORC2 Signaling and Is Associated with Clinicopathological Characteristics of Gastric Cancer.
Author: Wang, Yu-Gang|Xu, Ling|Jia, Rong-Rong|Wu, Qiong|Wang, Ting|Wei, Jue|Ma, Jia-Li|Shi, Min|Li, Zhao-Shen
PMID: 27010547
Journal: Cancer Res. 2016 May 15;76(10):3057-66.
Title: Human Helicase RECQL4 Drives Cisplatin Resistance in Gastric Cancer by Activating an AKT-YB1-MDR1 Signaling Pathway.
Author: Mo, Dongliang|Fang, Hongbo|Niu, Kaifeng|Liu, Jing|Wu, Meng|Li, Shiyou|Zhu, Tienian|Aleskandarany, Mohammed A|Arora, Arvind|Lobo, Dileep N|Madhusudan, Srinivasan|Balajee, Adayabalam S|Chi, Zhenfen|Zhao, Yongliang
PMID: 27013200
Journal: Dig Dis Sci. 2016 Jul;61(7):1941-9.
Title: Gastrointestinal Factor GDDR Attenuates Epithelial-Mesenchymal Transition in Gastric Cancer via Inhibiting AKT Signal.
Author: Fang, Cheng|Zhang, Ziqiang|Liu, Chaoxu|Wang, Gang|Wang, Fei|Zhao, Zhanwei|Li, Wenhui|Hua, Jin|Shuang, Jianbo|Du, Jianjun
PMID: 27017226
Journal: Clin Cancer Res. 2016 Oct 15;22(20):5097-5108.
Title: DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1.
Author: Ogitani, Yusuke|Aida, Tetsuo|Hagihara, Katsunobu|Yamaguchi, Junko|Ishii, Chiaki|Harada, Naoya|Soma, Masako|Okamoto, Hiromi|Oitate, Masataka|Arakawa, Shingo|Hirai, Takehiro|Atsumi, Ryo|Nakada, Takashi|Hayakawa, Ichiro|Abe, Yuki|Agatsuma, Toshinori
PMID: 27026201
Journal: Nutr Cancer. 2016;68(2):267-79.
Title: Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.
Author: Cui, Fengjie|Zan, Xinyi|Li, Yunhong|Sun, Wenjing|Yang, Yan|Ping, Lifeng
PMID: 27040446
Journal: Oncotarget. 2016 May 3;7(18):25391-407.
Title: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma.
Author: Huang, Baohua|Deng, Shuo|Loo, Ser Yue|Datta, Arpita|Yap, Yan Lin|Yan, Benedict|Ooi, Chia Huey|Dinh, Thuy Duong|Zhuo, Jingli|Tochhawng, Lalchhandami|Gopinadhan, Suma|Jegadeesan, Tamilarasi|Tan, Patrick|Salto-Tellez, Manuel|Yong, Wei Peng|Soong, Richie|Yeoh
PMID: 27058427
Journal: Oncol Lett. 2016 Apr;11(4):2661-2667.
Title: Upregulation of miR-34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC-7901 cells through inhibition of the PI3K/Akt signaling pathway.
Author: Wang, Guojun|Liu, Guanghui|Ye, Yanwei|Fu, Yang|Zhang, Xiefu
PMID: 27073535
Journal: Cell Biol Int. 2016 Jul;40(7):770-8.
Title: Oleanolic acid induces autophagic death in human gastric cancer cells in vitro and in vivo.
Author: Nie, Hao|Wang, Yu|Qin, Yong|Gong, Xing-Guo
PMID: 27079177
Journal: Eur J Pharmacol. 2016 Jun 15;781:164-72.
Title: DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation.
Author: Li, Hongyang|Sun, Li|de Carvalho, Evandro Lopes|Li, Xinxin|Lv, Xiaodan|Khan, Ghulam Jilany|Semukunzi, Herve|Yuan, Shengtao|Lin, Sensen
PMID: 27079642
Journal: Oncotarget. 2016 Jun 7;7(23):34356-70.
Title: Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition and analysis of their phosphorylation signaling pathways.
Author: Cui, Yuehong|Wang, Yan|Li, Hong|Li, Qian|Yu, Yiyi|Xu, Xiaojing|Xu, Bei|Liu, Tianshu
PMID: 27102302
Journal: Oncotarget. 2016 May 17;7(20):29507-19.
Title: Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway.
Author: Yuan, Wanqiong|Li, Ting|Mo, Xiaoning|Wang, Xiaolin|Liu, Baocai|Wang, Wenyan|Su, Yu|Xu, Lan|Han, Wenling
PMID: 27121055
Journal: Oncotarget. 2016 May 31;7(22):33152-64.
Title: AURKA induces EMT by regulating histone modification through Wnt/beta-catenin and PI3K/Akt signaling pathway in gastric cancer.
Author: Liu, Xi|Li, Zhaoxia|Song, Yue|Wang, Rui|Han, Lei|Wang, Qixue|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu
PMID: 27121204
Journal: Oncotarget. 2016 May 24;7(21):31322-35.
Title: TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression.
Author: Pei, Yao-Fei|Tao, Ran|Li, Jian-Fang|Su, Li-Ping|Yu, Bei-Qin|Wu, Xiong-Yan|Yan, Min|Gu, Qin-Long|Zhu, Zheng-Gang|Liu, Bing-Ya
PMID: 27121319
Journal: Sci Rep. 2016 May 5;6:25447.
Title: Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/beta-catenin pathway to enhance the stemness of gastric cancer.
Author: Bie, Qingli|Sun, Caixia|Gong, Aihua|Li, Chunye|Su, Zhaoliang|Zheng, Dong|Ji, Xiaoyun|Wu, Yumin|Guo, Qi|Wang, Shengjun|Xu, Huaxi
PMID: 27146881
Journal: Oncotarget. 2016 Jun 7;7(23):34190-200.
Title: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.
Author: Wu, Yan|Yao, Xiaoyuan|Zhu, Miaolin|Qian, Hai|Jiang, Lu|Lan, Ting|Wu, Min|Pang, Ji|Chen, Yongchang
PMID: 27147579
Journal: Pathol Oncol Res. 2016 Oct;22(4):797-805.
Title: The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines.
Author: Riquelme, Ismael|Tapia, Oscar|Espinoza, Jaime A|Leal, Pamela|Buchegger, Kurt|Sandoval, Alejandra|Bizama, Carolina|Araya, Juan Carlos|Peek, Richard M|Roa, Juan Carlos
PMID: 27156070
Journal: Oncogene. 2016 Dec 1;35(48):6189-6202.
Title: MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.
Author: Venturutti, L|Cordo Russo, R I|Rivas, M A|Mercogliano, M F|Izzo, F|Oakley, R H|Pereyra, M G|De Martino, M|Proietti, C J|Yankilevich, P|Roa, J C|Guzman, P|Cortese, E|Allemand, D H|Huang, T H|Charreau, E H|Cidlowski, J A|Schillaci, R|Elizalde, P V
PMID: 27157613
Journal: Am J Transl Res. 2016 Feb 15;8(2):742-8. eCollection 2016.
Title: BRD7: a novel tumor suppressor gene in different cancers.
Author: Yu, Xin|Li, Zheng|Shen, Jianxiong
PMID: 27158366
Journal: Am J Transl Res. 2016 Feb 15;8(2):1164-71. eCollection 2016.
Title: Growth inhibition of human gastric adenocarcinoma cells in vitro by STO-609 is independent of calcium/calmodulin-dependent protein kinase kinase-beta and adenosine monophosphate-activated protein kinase.
Author: Ma, Zhiming|Wen, Dacheng|Wang, Xudong|Yang, Longfei|Liu, Tianzhou|Liu, Jingjing|Zhu, Jiaming|Fang, Xuedong
PMID: 27158402
Journal: Oncotarget. 2016 Jun 14;7(24):36865-36884.
Title: JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
Author: Qian, Jing|Zhu, Weiyou|Wang, Keming|Ma, Lin|Xu, Jin|Xu, Tongpeng|Roe, Oluf Dimitri|Li, Aiping|Zhou, Jianwei|Shu, Yongqian
PMID: 27167206
Journal: Mol Med Rep. 2016 Jul;14(1):413-9.
Title: Evodiamine sensitizes BGC-823 gastric cancer cells to radiotherapy in vitro and in vivo.
Author: Hu, Chengqi|Gao, Xuexiang|Han, Yuanyuan|Guo, Qi|Zhang, Kailiang|Liu, Miaomiao|Wang, Yugang|Wang, Jing
PMID: 27176933
Journal: Oncol Res. 2016;24(1):17-23.
Title: Overexpression of SASH1 Inhibits TGF-beta1-Induced EMT in Gastric Cancer Cells.
Author: Zong, Wei|Yu, Chen|Wang, Ping|Dong, Lei
PMID: 27178818
Journal: Cancer Res. 2016 Jul 1;76(13):3895-903.
Title: M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers.
Author: Ohashi, Yoshimi|Okamura, Mutsumi|Hirosawa, Asaka|Tamaki, Naomi|Akatsuka, Akinobu|Wu, Kuo-Ming|Choi, Hyeong-Wook|Yoshimatsu, Kentaro|Shiina, Isamu|Yamori, Takao|Dan, Shingo
PMID: 27197184
Journal: World J Gastroenterol. 2016 May 21;22(19):4638-50.
Title: Recent updates of precision therapy for gastric cancer: Towards optimal tailored management.
Author: Joo, Moon Kyung|Park, Jong-Jae|Chun, Hoon Jai
PMID: 27217696
Journal: Clin Cancer Res. 2016 Dec 15;22(24):6164-6175.
Title: An FGFR3 Autocrine Loop Sustains Acquired Resistance to Trastuzumab in Gastric Cancer Patients.
Author: Piro, Geny|Carbone, Carmine|Cataldo, Ivana|Di Nicolantonio, Federica|Giacopuzzi, Simone|Aprile, Giuseppe|Simionato, Francesca|Boschi, Federico|Zanotto, Marco|Mina, Maria Mihaela|Santoro, Raffaela|Merz, Valeria|Sbarbati, Andrea|de Manzoni, Giovanni|Scarpa,
PMID: 27267856
Journal: Oncol Rep. 2016 Aug;36(2):1173-9.
Title: Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo.
Author: Su, Chin-Cheng|Chiu, Tsung-Lang
PMID: 27277844
Journal: Int J Mol Med. 2016 Aug;38(2):619-26.
Title: Quercetin inhibits the growth of human gastric cancer stem cells by inducing mitochondrial-dependent apoptosis through the inhibition of PI3K/Akt signaling.
Author: Shen, Xinsheng|Si, Yaqing|Wang, Zhao|Wang, Jiachen|Guo, Yongqiang|Zhang, Xiefu
PMID: 27278820
Journal: Phytomedicine. 2016 Jul 15;23(8):818-27.
Title: The natural secolignan peperomin E induces apoptosis of human gastric carcinoma cells via the mitochondrial and PI3K/Akt signaling pathways in vitro and in vivo.
Author: Wang, Xin-Zhi|Cheng, Ying|Wu, Hao|Li, Na|Liu, Rui|Yang, Xiao-Lin|Qiu, Yun-Ying|Wen, Hong-Mei|Liang, Jing-Yu
PMID: 27288917
Journal: Cancer Biomark. 2016 Jun 7;17(1):1-10.
Title: Autophagy regulation and its role in gastric cancer and colorectal cancer.
Author: Zhou, Huangyan|Yuan, Min|Yu, Qiongfang|Zhou, Xiaoyan|Min, Weiping|Gao, Dian
PMID: 27314289
Journal: Cancer Lett. 2016 Sep 28;380(1):20-30.
Title: The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer.
Author: Wang, Qiwei|Zhang, Xiaotian|Shen, Enyun|Gao, Jing|Cao, Fengqi|Wang, Xiaojuan|Li, Yilin|Tian, Tiantian|Wang, Jingyuan|Chen, Zuhua|Wang, Jiayuan|Shen, Lin
PMID: 27317872
Journal: Oncotarget. 2016 Jul 19;7(29):46127-46141.
Title: Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.
Author: Zhang, Qian|Yan, Hai-Bo|Wang, Jie|Cui, Shu-Jian|Wang, Xiao-Qing|Jiang, Ying-Hua|Feng, Li|Yang, Peng-Yuan|Liu, Feng
PMID: 27323812
Journal: Tumour Biol. 2016 Sep;37(9):12403-12410.
Title: Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3beta signaling in gastric cancer.
Author: Dai, Jin|Qian, Chenchen|Su, Mingli|Chen, Minhu|Chen, Jie
PMID: 27323966
Journal: Pharmazie. 2016 May;71(5):280-4.
Title: Overexpression of RRM2 in gastric cancer cell promotes their invasiveness via AKT/NF-kappaB signaling pathway.
Author: Zhong, Zhaohui|Cao, Yuandong|Yang, Shen|Zhang, Shukun
PMID: 27348973
Journal: Oncol Rep. 2016 Aug;36(2):779-86.
Title: Ubiquitin-conjugating enzyme UbcH10 promotes gastric cancer growth and is a potential biomarker for gastric cancer.
Author: Yang, Mengxuan|Qu, Yingying|Shi, Rongliang|Wu, Xubo|Su, Chang|Hu, Zhiqiu|Chang, Qimeng|Liu, Shaoqun|Pan, Gaofeng|Lei, Ming|Xie, Fubo|Tu, Shiwei|Tao, Weikang|Zhou, He|Hu, Gang|Zhang, Ziping
PMID: 27349176
Journal: Mol Med Rep. 2016 Aug;14(2):1817-22.
Title: Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cells.
Author: Zhao, Hongyan|Zhao, Dali|Jin, Huilin|Li, Hongwei|Yang, Xiaoying|Zhuang, Liwei|Liu, Tiefu
PMID: 27357249
Journal: Sci Rep. 2016 Jul 8;6:29382.
Title: Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer.
Author: Chen, Jing|Guo, Jiawei|Chen, Zhi|Wang, Jieqiong|Liu, Mingyao|Pang, Xiufeng
PMID: 27387652
Journal: BMC Cancer. 2016 Jul 7;16:400.
Title: Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review.
Author: Harada, Kazuto|Baba, Yoshifumi|Shigaki, Hironobu|Ishimoto, Takatsugu|Miyake, Keisuke|Kosumi, Keisuke|Tokunaga, Ryuma|Izumi, Daisuke|Ohuchi, Mayuko|Nakamura, Kenichi|Kiyozumi, Yuki|Kurashige, Junji|Iwatsuki, Masaaki|Miyamoto, Yuji|Sakamoto, Yasuo|Yoshida,
PMID: 27388016
Journal: Oncotarget. 2016 Aug 23;7(34):54445-54462.
Title: Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation.
Author: Saisana, Marina|Griffin, S Michael|May, Felicity E B
PMID: 27437872
Journal: Oncol Lett. 2016 Aug;12(2):783-787.
Title: Role of periostin in esophageal, gastric and colon cancer.
Author: Moniuszko, Tadeusz|Wincewicz, Andrzej|Koda, Mariusz|Domyslawska, Izabela|Sulkowski, Stanislaw
PMID: 27446351
Journal: Tumour Biol. 2016 Sep;37(9):12813-12821.
Title: ZNF143 enhances metastasis of gastric cancer by promoting the process of EMT through PI3K/AKT signaling pathway.
Author: Wei, Song|Wang, Linjun|Zhang, Lei|Li, Bowen|Li, Zheng|Zhang, Qun|Wang, Jiwei|Chen, Liang|Sun, Guangli|Li, Qing|Xu, Hao|Zhang, Diancai|Xu, Zekuan
PMID: 27449034
Journal: Oncotarget. 2016 Aug 23;7(34):54744-54757.
Title: PAX3 is a novel tumor suppressor by regulating the activities of major signaling pathways and transcription factor FOXO3a in thyroid cancer.
Author: Liu, Wei|Sui, Fang|Liu, Jiazhe|Wang, Meichen|Tian, Sijia|Ji, Meiju|Shi, Bingyin|Hou, Peng
PMID: 27458157
Journal: Int Immunopharmacol. 2016 Oct;39:113-120.
Title: Dopamine D2 receptor suppresses gastric cancer cell invasion and migration via inhibition of EGFR/AKT/MMP-13 pathway.
Author: Huang, Hongli|Wu, Kaiming|Ma, Jun|Du, Yanlei|Cao, Chuangyu|Nie, Yuqiang
PMID: 27468100
Journal: Biomed Pharmacother. 2016 Aug;82:479-88.
Title: CXCL10/CXCR3 axis promotes the invasion of gastric cancer via PI3K/AKT pathway-dependent MMPs production.
Author: Zhou, Hongfeng|Wu, Jin|Wang, Tianjiao|Zhang, Xufeng|Liu, Dan
PMID: 27470388
Journal: Mar Drugs. 2016 Jul 27;14(8). pii: md14080142.
Title: Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells.
Author: Wu, Yu-Jen|Wong, Bing-Sang|Yea, Shu-Hao|Lu, Chi-I|Weng, Shun-Hsiang
PMID: 27472346
Journal: Int J Oncol. 2016 Oct;49(4):1589-99.
Title: Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer.
Author: Zeng, Yang|Fu, Meng|Wu, Gang-Wei|Zhang, An-Zu|Chen, Jin-Ping|Lin, Hong-Yue|Fu, Yong-An|Jia, Jing|Cai, Zong-Da|Wu, Xiao-Jian|Lan, Ping
PMID: 27499479
Journal: Onco Targets Ther. 2016 Jul 19;9:4387-96.
Title: MK-2206 co-treatment with 5-fluorouracil or doxorubicin enhances chemosensitivity and apoptosis in gastric cancer by attenuation of Akt phosphorylation.
Author: Jin, Piaopiao|Wong, Chi Chun|Mei, Sibin|He, Xingkang|Qian, Yun|Sun, Leimin
PMID: 27499633
Journal: Mol Med Rep. 2016 Oct;14(4):3452-8.
Title: Exosomes derived from human mesenchymal stem cells promote gastric cancer cell growth and migration via the activation of the Akt pathway.
Author: Gu, Hongbing|Ji, Runbi|Zhang, Xu|Wang, Mei|Zhu, Wei|Qian, Hui|Chen, Yongchang|Jiang, Pengcheng|Xu, Wenrong
PMID: 27513187
Journal: PLoS One. 2016 Aug 12;11(8):e0158961.
Title: MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer.
Author: Yu, Beiqin|Lv, Xin|Su, Liping|Li, Jianfang|Yu, Yingyan|Gu, Qinlong|Yan, Min|Zhu, Zhenggang|Liu, Bingya
PMID: 27518872
Journal: Int J Mol Sci. 2016 Aug 15;17(8). pii: ijms17081337.
Title: T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death.
Author: Chiu, Chang-Fang|Weng, Jing-Ru|Jadhav, Appaso|Wu, Chia-Yung|Sargeant, Aaron M|Bai, Li-Yuan
PMID: 27537872
Journal: J Biol Chem. 2016 Sep 30;291(40):20891-20899.
Title: The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer.
Author: Watanabe, Kenta|Hirata, Michiko|Tominari, Tsukasa|Matsumoto, Chiho|Fujita, Hidenori|Yonekura, Kazuhiko|Murphy, Gillian|Nagase, Hideaki|Miyaura, Chisato|Inada, Masaki
PMID: 27539855
Journal: Onco Targets Ther. 2016 Aug 9;9:4859-66.
Title: Oncogenic NanogP8 expression regulates cell proliferation and migration through the Akt/mTOR signaling pathway in human gastric cancer - SGC-7901cell line.
Author: Jiang, Zheng|Liu, Yao|Wang, Chuan
PMID: 27563247
Journal: J BUON. 2016 May-Jun;21(3):609-17.
Title: Amarogentin secoiridoid inhibits in vivo cancer cell growth in xenograft mice model and induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway.
Author: Zhao, Jian-Guo|Zhang, Ling|Xiang, Xiao-Jun|Yu, Feng|Ye, Wan-Li|Wu, Dong-Ping|Wang, Jian-Fang|Xiong, Jian-Ping
PMID: 27569081
Journal: Oncol Rep. 2016 Oct;36(4):2216-24.
Title: RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer.
Author: Wang, Wenwen|Liu, Juan|Qi, Jianni|Zhang, Junyong|Zhu, Qiang|Qin, Chengyong
PMID: 27572296
Journal: Oncol Rep. 2016 Oct;36(4):1819-28.
Title: PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN.
Author: Xiong, Jianbo|Li, Zhengrong|Zhang, Yang|Li, Daojiang|Zhang, Guoyang|Luo, Xianshi|Jie, Zhigang|Liu, Yi|Cao, Yi|Le, Zhibiao|Tan, Shengxing|Zou, Wenyu|Gong, Peitao|Qiu, Lingyu|Li, Yuanyuan|Wang, Huan|Chen, Heping
PMID: 27572739
Journal: Adv Exp Med Biol. 2016;908:441-78.
Title: Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer.
Author: Ding, Lin|El Zaatari, Mohamad|Merchant, Juanita L
PMID: 27573785
Journal: J Hematol Oncol. 2016 Aug 31;9(1):76.
Title: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway.
Author: Liu, Jing|Pan, Changqie|Guo, Lihong|Wu, Mengwan|Guo, Jing|Peng, Sheng|Wu, Qianying|Zuo, Qiang
PMID: 27581375
Journal: Oncotarget. 2016 Oct 4;7(40):65418-65428.
Title: Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies.
Author: Lan, Ting|Pang, Ji|Wu, Yan|Zhu, Miaolin|Yao, Xiaoyuan|Wu, Min|Qian, Hai|Zhang, Zhenyu|Gao, Jizong|Chen, Yongchang
PMID: 27589842
Journal: Oncotarget. 2016 Oct 11;7(41):66989-67003.
Title: MicroRNA-21 promotes TGF-beta1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression.
Author: Li, Chang|Song, Lei|Zhang, Zhuo|Bai, Xiao-Xue|Cui, Ming-Fu|Ma, Lian-Jun
PMID: 27611950
Journal: Tumour Biol. 2016 Nov;37(11):14637-14651.
Title: Bone marrow-derived mesenchymal stem cells increase drug resistance in CD133-expressing gastric cancer cells by regulating the PI3K/AKT pathway.
Author: Ji, Nuo|Yu, Ji-Wei|Ni, Xiao-Chun|Wu, Ju-Gang|Wang, Shou-Lian|Jiang, Bo-Jian
PMID: 27619680
Journal: Sci Rep. 2016 Sep 14;6:33204.
Title: Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents.
Author: Zhang, Xiao-Fei|Sun, Rong-Qin|Jia, Yi-Fan|Chen, Qing|Tu, Rong-Fu|Li, Ke-Ke|Zhang, Xiao-Dong|Du, Run-Lei|Cao, Ri-Hui
PMID: 27625151
Journal: J Hematol Oncol. 2016 Sep 20;9(1):90.
Title: Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs.
Author: Wang, Xiaofeng|Wang, Chang|Zhang, Xiaowei|Hua, Ruixi|Gan, Lu|Huang, Mingzhu|Zhao, Liqin|Ni, Sujie|Guo, Weijian
PMID: 27644439
Journal: Int J Med Sci. 2016 Sep 7;13(9):708-16.
Title: Effects for Sequential Treatment of siAkt and Paclitaxel on Gastric Cancer Cell Lines.
Author: Ku, Minhee|Kang, Myounghwa|Suh, Jin-Suck|Yang, Jaemoon
PMID: 27648001
Journal: Ann Clin Lab Sci. 2016 Sep;46(5):457-62.
Title: Matrine Suppresses Proliferation and Invasion of SGC7901 Cells through Inactivation of PI3K/Akt/uPA Pathway.
Author: Peng, Xiaochun|Zhou, Dawei|Wang, Xianwang|Hu, Zhifan|Yan, Yan|Huang, Jiangrong
PMID: 27650610
Journal: Oncotarget. 2016 Nov 8;7(45):72990-73002.
Title: Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
Author: Wang, Sai-Qi|Wang, Cong|Chang, Li-Ming|Zhou, Kai-Rui|Wang, Jun-Wei|Ke, Yu|Yang, Dong-Xiao|Shi, Hong-Ge|Wang, Ran|Shi, Xiao-Li|Ma, Li-Ying|Liu, Hong-Min
PMID: 27659528
Journal: Oncol Lett. 2016 Oct;12(4):2710-2715.
Title: Expression of early growth response gene-1 in precancerous lesions of gastric cancer.
Author: Park, Seon-Young|Kim, Ji-Young|Lee, Su-Mi|Chung, Jin Ook|Lee, Kyung-Hwa|Jun, Chung-Hwan|Park, Chang-Hwan|Kim, Hyun-Soo|Choi, Sung-Kyu|Rew, Jong-Sun|Jung, Young-Do|Lee, Yong Han
PMID: 27698846
Journal: Oncol Res. 2016;24(5):287-293.
Title: Knockdown of Rap1b Enhances Apoptosis and Autophagy in Gastric Cancer Cells via the PI3K/Akt/mTOR Pathway.
Author: Li, Yazhou|Liu, Yang|Shi, Feiyu|Cheng, Liang|She, Junjun
PMID: 27712585
Journal: Am J Cancer Res. 2016 Sep 1;6(9):1935-1948. eCollection 2016.
Title: Identification of HRAS as cancer-promoting gene in gastric carcinoma cell aggressiveness.
Author: Wu, Xiao Yu|Liu, Wen Tao|Wu, Zhen Feng|Chen, Che|Liu, Jia Yun|Wu, Guan Nan|Yao, Xue Quan|Liu, Fu Kun|Li, Gang
PMID: 27725900
Journal: Oncol Rep. 2016 Dec;36(6):3664-3672.
Title: HPIP promotes gastric cancer cell proliferation through activation of cap-dependent translation.
Author: Chen, Bing|Zhao, Jin|Zhang, Shengbin|Zhang, Yonggang|Huang, Zonghai
PMID: 27748944
Journal: Onco Targets Ther. 2016 Oct 3;9:6009-6019.
Title: miR-590-5p regulates gastric cancer cell growth and chemosensitivity through RECK and the AKT/ERK pathway.
Author: Shen, Bo|Yu, Shaorong|Zhang, Yan|Yuan, Yuan|Li, Xiaoyou|Zhong, Jian|Feng, Jifeng
PMID: 27757042
Journal: Oncotarget. 2016 Dec 20;7(51):84860-84871.
Title: Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.
Author: Nonagase, Yoshikane|Yonesaka, Kimio|Kawakami, Hisato|Watanabe, Satomi|Haratani, Koji|Takahama, Takayuki|Takegawa, Naoki|Ueda, Hiroto|Tanizaki, Junko|Hayashi, Hidetoshi|Yoshida, Takeshi|Takeda, Masayuki|Chiba, Yasutaka|Tamura, Takao|Nakagawa, Kazuhiko|Tsur
PMID: 27768588
Journal: Oncol Rep. 2016 Dec;36(6):3716.
Title: [Retracted] Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo.
Author: Zhang, Jing|Zhu, Jin-Shui|Zhou, Zhou|Chen, Wei-Xiong|Chen, Ni-Wei
PMID: 27779688
Journal: Cell Physiol Biochem. 2016;39(6):2149-2157.
Title: WIN 55,212-2 Inhibits the Epithelial Mesenchymal Transition of Gastric Cancer Cells via COX-2 Signals.
Author: Xian, Xiangshu|Huang, Liuye|Zhang, Bo|Wu, Chengrong|Cui, Jun|Wang, Zhihua
PMID: 27802436
Journal: Phytomedicine. 2016 Dec 1;23(13):1671-1679.
Title: Sageone, a diterpene from Rosmarinus officinalis, synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells.
Author: Shrestha, Sabina|Song, Yeon Woo|Kim, Hyeonji|Lee, Dong Sun|Cho, Somi Kim
PMID: 27823632
Journal: Am J Transl Res. 2016 Oct 15;8(10):4172-4183. eCollection 2016.
Title: PLK1 promotes epithelial-mesenchymal transition and metastasis of gastric carcinoma cells.
Author: Cai, Xiao Peng|Chen, Liang Dong|Song, Hai Bin|Zhang, Chun Xiao|Yuan, Ze Wei|Xiang, Zhen Xian
PMID: 27830001
Journal: J BUON. 2016 Sept-Oct;21(5):1332.
Title: Erratum: Amarogentin secoiridoid inhibits in vivo cancer cell growth in xenograft mice model and induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway.
Author: Zhao, Jian-Guo|Zhang, Ling|Xiang, Xiao-Jun|Yu, Feng|Yu, Feng|Ye, Wan-Li|Wu, Dong-Ping|Wang, Jian-Fang|Xiong, Jian-Ping
PMID: 27837645
Journal: World J Gastroenterol. 2016 Nov 7;22(41):9141-9153.
Title: HER2-induced metastasis is mediated by AKT/JNK/EMT signaling pathway in gastric cancer.
Author: Choi, Yiseul|Ko, Young San|Park, Jinju|Choi, Youngsun|Kim, Younghoon|Pyo, Jung-Soo|Jang, Bo Gun|Hwang, Douk Ho|Kim, Woo Ho|Lee, Byung Lan
PMID: 27895401
Journal: Oncol Lett. 2016 Nov;12(5):3485-3491.
Title: PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition.
Author: Wang, Shuanhu|Li, Chenglong|Wang, Wenbin|Xing, Chungen
PMID: 27900025
Journal: Tumour Biol. 2016 Nov 30. pii: 10.1007/s13277-016-5448-5.
Title: LncRNA HOTAIR promotes cisplatin resistance in gastric cancer by targeting miR-126 to activate the PI3K/AKT/MRP1 genes.
Author: Yan, Jin|Dang, Yini|Liu, Shiyu|Zhang, Yifeng|Zhang, Guoxin
PMID: 27900563
Journal: PLoS One. 2016 Dec 22;11(12):e0168085.
Title: Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric Cancer.
Author: Cao, Guo-Dong|Xu, Xing-Yu|Zhang, Jia-Wei|Chen, Bo|Xiong, Mao-Ming
PMID: 28005970
Journal: Oncol Res. 2016 Oct 27;24(6):487-494.
Title: CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line.
Author: Zhang, Jian|Shi, ZhenFeng|Huang, JinXing|Zou, XiaoGuang
PMID: 28281969
Journal: Ann Surg Oncol. 2017 Feb;24(2):594-602.
Title: Overexpression of Transmembrane Protein BST2 is Associated with Poor Survival of Patients with Esophageal, Gastric, or Colorectal Cancer.
Author: Mukai, Shoichiro|Oue, Naohide|Oshima, Takashi|Mukai, Risa|Tatsumoto, Yoshiko|Sakamoto, Naoya|Sentani, Kazuhiro|Tanabe, Kazuaki|Egi, Hiroyuki|Hinoi, Takao|Ohdan, Hideki|Yasui, Wataru
PMID: 26832883
Journal: Oncogene. 2017 Feb 16;36(7):999-1011.
Title: RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3.
Author: Jang, J-W|Kim, M-K|Lee, Y-S|Lee, J-W|Kim, D-M|Song, S-H|Lee, J-Y|Choi, B-Y|Min, B|Chi, X-Z|Bae, S-C
PMID: 27425596
Journal: Gut. 2017 May;66(5):761-762.
Title: Helicobacter pylori-induced cell death is counteracted by NF-kappaB-mediated transcription of DARPP-32.
Author: Zhu, Shoumin|Soutto, Mohammed|Chen, Zheng|Peng, DunFa|Romero-Gallo, Judith|Krishna, Uma S|Belkhiri, Abbes|Washington, M Kay|Peek, Richard|El-Rifai, Wael
PMID: 27590997
Journal: Oncol Res. 2017 Jul 5;25(6):853-861.
Title: miR-326 Inhibits Gastric Cancer Cell Growth Through Downregulating NOB1.
Author: Ji, Sheqing|Zhang, Bin|Kong, Ye|Ma, Fei|Hua, Yawei
PMID: 27733214
Journal: Mol Cell Biochem. 2017 Jan;424(1-2):173-183.
Title: Akt/AMPK/mTOR pathway was involved in the autophagy induced by vitamin E succinate in human gastric cancer SGC-7901 cells.
Author: Yu, Yang|Hou, Liying|Song, Huacui|Xu, Peixiang|Sun, Yue|Wu, Kun
PMID: 27796683
Journal: Cancer Lett. 2017 Jan 28;385:28-38.
Title: CXCL1 from tumor-associated lymphatic endothelial cells drives gastric cancer cell into lymphatic system via activating integrin beta1/FAK/AKT signaling.
Author: Wang, Zhixiong|Wang, Zhao|Li, Guanghua|Wu, Hui|Sun, Kaiyu|Chen, Jianhui|Feng, Yun|Chen, Chuangqi|Cai, Shirong|Xu, Jianbo|He, Yulong
PMID: 27832972
Journal: Int J Pharm. 2017 Jan 30;517(1-2):25-34.
Title: Fabrication of self-assembled chitosan-dispersed LDL nanoparticles for drug delivery with a one-step green method.
Author: Tian, Jing|Xu, Shasha|Deng, Hongbing|Song, Xinxing|Li, Xiujuan|Chen, Jiajia|Cao, Feng|Li, Bin
PMID: 27845214
Journal: Oncotarget. 2017 Jan 3;8(1):1247-1261.
Title: HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs.
Author: He, Xujun|Liu, Zhengchuang|Xia, Yingjie|Xu, Ji|Lv, Guocai|Wang, Lu|Ma, Tonghui|Jiang, Liping|Mou, Yiping|Jiang, Xiaoting|Ma, Jie|Zhao, Zhongkuo|Ni, Haibin|Xu, Wenjuan|Ru, Guoqing|Huang, Dongsheng|Tao, Houquan
PMID: 27901487
Journal: Int J Biochem Cell Biol. 2017 Mar;84:14-21.
Title: Omental adipocytes enhance the invasiveness of gastric cancer cells by oleic acid-induced activation of the PI3K-Akt signaling pathway.
Author: Xiang, Fan|Wu, Ke|Liu, Yulin|Shi, Liang|Wang, Di|Li, Gang|Tao, Kaixiong|Wang, Guobin
PMID: 27956048
Journal: Biochem Biophys Res Commun. 2017 Apr 8;485(3):598-605.
Title: Irisin suppresses the migration, proliferation, and invasion of lung cancer cells via inhibition of epithelial-to-mesenchymal transition.
Author: Shao, Lei|Li, Huanjie|Chen, Jian|Song, Haibo|Zhang, Yuzhu|Wu, Fei|Wang, Wenjuan|Zhang, Wen|Wang, Fang|Li, Hui|Tang, Dongqi
PMID: 27986567
Journal: Cancer Sci. 2017 Mar;108(3):322-330.
Title: MET4 expression predicts poor prognosis of gastric cancers with Helicobacter pylori infection.
Author: Sakamoto, Naoko|Tsujimoto, Hironori|Takahata, Risa|Cao, Brian|Zhao, Ping|Ito, Nozomi|Shimazaki, Hideyuki|Ichikura, Takashi|Hase, Kazuo|Vande Woude, George F|Shinomiya, Nariyoshi
PMID: 28012218
Journal: Ann Oncol. 2017 Mar 1;28(3):547-554.
Title: Rapamycin-insensitive companion of mTOR (RICTOR) amplification defines a subset of advanced gastric cancer and is sensitive to AZD2014-mediated mTORC1/2 inhibition.
Author: Kim, S T|Kim, S Y|Klempner, S J|Yoon, J|Kim, N|Ahn, S|Bang, H|Kim, K-M|Park, W|Park, S H|Park, J O|Park, Y S|Lim, H Y|Lee, S H|Park, K|Kang, W K|Lee, J
PMID: 28028034
Journal: Oncotarget. 2017 Jan 24;8(4):6718-6729.
Title: Positive feedback loop of IL-1beta/Akt/RARalpha/Akt signaling mediates oncogenic property of RARalpha in gastric carcinoma.
Author: Ren, Hong-Yue|Liu, Fan|Huang, Gui-Li|Liu, Yu|Shen, Jin-Xing|Zhou, Pan|Liu, Wen-Ming|Shen, Dong-Yan
PMID: 28035062
Journal: Med Sci Monit. 2017 Jan 6;23:71-77.
Title: miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway.
Author: Yu, Jinzhong|Wang, Ruijie|Chen, Jianshe|Wu, Jinfeng|Dang, Zhongqin|Zhang, Qinsheng|Li, Bo
PMID: 28057912
Journal: Hum Cell. 2017 Apr;30(2):124-132.
Title: Liver X receptor alpha (LXRalpha) promoted invasion and EMT of gastric cancer cells by regulation of NF-kappaB activity.
Author: Ji, Linhua|Zhang, Bin|Zhao, Gang
PMID: 28091828
Journal: Sci Rep. 2017 Jan 19;7:40802.
Title: Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation.
Author: Yu, Huangfei|Xia, Hongwei|Tang, Qiulin|Xu, Huanji|Wei, Guoqing|Chen, Ying|Dai, Xinyu|Gong, Qiyong|Bi, Feng
PMID: 28102288
Journal: Oncol Res. 2017 Aug 7;25(7):1153-1159.
Title: 3-Phosphoinositide Dependent Protein Kinase-1 (PDK-1) Promotes Migration and Invasion in Gastric Cancer Cells Through Activating the NF-kappaB Pathway.
Author: Wu, Ning|He, Changyu|Zhu, Bohui|Jiang, Jinling|Chen, Yiwen|Ma, Tao
PMID: 28109078
Journal: Oncol Res. 2017 Aug 7;25(7):1169-1176.
Title: MicroRNA-133a Inhibits Proliferation of Gastric Cancer Cells by Downregulating ERBB2 Expression.
Author: Li, Chang|Li, Xiaoping|Gao, Shuohui|Li, Chang|Ma, Lianjun
PMID: 28109082
Journal: J Exp Clin Cancer Res. 2017 Jan 23;36(1):17.
Title: Regulation of TRIM24 by miR-511 modulates cell proliferation in gastric cancer.
Author: Fang, Ziling|Zhang, Ling|Liao, Quan|Wang, Yi|Yu, Feng|Feng, Miao|Xiang, Xiaojun|Xiong, Jianping
PMID: 28114950
Journal: Int J Mol Sci. 2017 Jan 22;18(1). pii: ijms18010220.
Title: Decreased Sp1 Expression Mediates Downregulation of SHIP2 in Gastric Cancer Cells.
Author: Ye, Yan|Qian, Xue Yi|Xiao, Miao Miao|Shao, Yu Ling|Guo, Li Mei|Liao, Dong Ping|Da, Jie|Zhang, Lin Jie|Xu, Jiegou
PMID: 28117748
Journal: J Exp Clin Cancer Res. 2017 Jan 26;36(1):19.
Title: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Author: Xu, Jiahui|Liu, Deying|Niu, Huilin|Zhu, Guifang|Xu, Yangwei|Ye, Danli|Li, Jian|Zhang, Qingling
PMID: 28126034
Journal: Exp Cell Res. 2017 Mar 1;352(1):34-44.
Title: Pseudolaric acid B inhibits gastric cancer cell metastasis in vitro and in haematogenous dissemination model through PI3K/AKT, ERK1/2 and mitochondria-mediated apoptosis pathways.
Author: Wang, Dan|Xin, Yan|Tian, Yanqiu|Li, Wenhui|Sun, Dan|Yang, Yi
PMID: 28132880
Journal: Proteomics Clin Appl. 2017 Jul;11(7-8).
Title: Proteomic analysis of cell cycle arrest and differentiation induction caused by ATPR, a derivative of all-trans retinoic acid, in human gastric cancer SGC-7901 cells.
Author: Xia, Quan|Zhao, Yingli|Wang, Jiali|Qiao, Wenhao|Zhang, Dongling|Yin, Hao|Xu, Dujuan|Chen, Feihu
PMID: 28164444
Journal: Cancer Gene Ther. 2017 Apr;24(4):180-188.
Title: Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition.
Author: Yin, H|Huang, X|Tao, M|Hu, Q|Qiu, J|Chen, W|Wu, J|Xie, Y
PMID: 28186089
Journal: Free Radic Biol Med. 2017 May;106:24-37.
Title: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author: Wang, Gangyang|Zhang, Tao|Sun, Wei|Wang, Hongsheng|Yin, Fei|Wang, Zhuoying|Zuo, Dongqing|Sun, Mengxiong|Zhou, Zifei|Lin, Binhui|Xu, Jing|Hua, Yingqi|Li, Haoqing|Cai, Zhengdong
PMID: 28188923
Journal: Oncotarget. 2017 Mar 14;8(11):18177-18184.
Title: Role of the PEBP4 protein in the development and metastasis of gastric cancer.
Author: Wu, Zijian|Liu, Bin|Zheng, Xuemin|Hou, Huijing|Li, Ying
PMID: 28193908
Journal: Int J Oncol. 2017 Mar;50(3):911-919.
Title: Cordycepin induces apoptosis in SGC7901 cells through mitochondrial extrinsic phosphorylation of PI3K/Akt by generating ROS.
Author: Nasser, Moussa Ide|Masood, Muqaddas|Wei, Wei|Li, Xiaochun|Zhou, Yifa|Liu, Bao|Li, Jiang|Li, Xiaomeng
PMID: 28197639
Journal: J Pathol Transl Med. 2017 Mar;51(2):103-121.
Title: Molecular Testing for Gastrointestinal Cancer.
Author: Lee, Hye Seung|Kim, Woo Ho|Kwak, Yoonjin|Koh, Jiwon|Bae, Jeong Mo|Kim, Kyoung-Mee|Chang, Mee Soo|Han, Hye Seung|Kim, Joon Mee|Kim, Hwal Woong|Chang, Hee Kyung|Choi, Young Hee|Park, Ji Y|Gu, Mi Jin|Lhee, Min Jin|Kim, Jung Yeon|Kim, Hee Sung|Cho, Mee-Yon
PMID: 28219002
Journal: Br J Cancer. 2017 Mar 28;116(7):903-911.
Title: Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells.
Author: Liang, Xin|Shi, Haiyang|Yang, Liyan|Qiu, Cen|Lin, Shengchao|Qi, Yingxue|Li, Jiyu|Zhao, Aiguang|Liu, Jianwen
PMID: 28222070
Journal: Mol Cancer Ther. 2017 Jun;16(6):1145-1154.
Title: Resistance Mechanism against Trastuzumab in HER2-Positive Cancer Cells and Its Negation by Src Inhibition.
Author: Jin, Mei Hua|Nam, Ah-Rong|Park, Ji Eun|Bang, Ju-Hee|Bang, Yung-Jue|Oh, Do-Youn
PMID: 28223426
Journal: Altern Ther Health Med. 2017 Sep;23(5):42-48.
Title: Proapoptotic and Growth-inhibitory Effects of Plumbagin on Human Gastric Cancer Cells Via Suppression of Signal Transducer and Activator of Transcription 3 and Protein Kinase B.
Author: Li, Jing|Li, Jia|Cai, Guowei|Shen, Lin|Lu, Furong
PMID: 28236621
Journal: Onco Targets Ther. 2017 Feb 20;10:1049-1058.
Title: MicroRNA-320 inhibits invasion and induces apoptosis by targeting CRKL and inhibiting ERK and AKT signaling in gastric cancer cells.
Author: Zhao, Yue|Dong, Qianze|Wang, Enhua
PMID: 28255248
Journal: Br J Pharmacol. 2017 May;174(10):1131-1146.
Title: Curcuminoid EF24 enhances the anti-tumour activity of Akt inhibitor MK-2206 through ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in gastric cancer.
Author: Chen, Xi|Dai, Xuanxuan|Zou, Peng|Chen, Weiqian|Rajamanickam, Vinothkumar|Feng, Chen|Zhuge, Weishan|Qiu, Chenyu|Ye, Qingqing|Zhang, Xiaohua|Liang, Guang
PMID: 28255993
Journal: Oncol Rep. 2017 Apr;37(4):2441-2448.
Title: MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3.
Author: Liu, Yanqi|Sun, Yanhong|Zhao, Aizhen
PMID: 28260021
Journal: Int J Oncol. 2017 Apr;50(4):1116-1126.
Title: UBE2C induces EMT through Wnt/betacatenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A.
Author: Wang, Rui|Song, Yue|Liu, Xi|Wang, Qixue|Wang, Yunfei|Li, Liwei|Kang, Chunsheng|Zhang, Qingyu
PMID: 28260026
Journal: Oncol Rep. 2017 Apr;37(4):2041-2048.
Title: Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300.
Author: Wang, Liping|Huang, Xin|Chai, Yurong|Zou, Liyang|Chedrawe, Matthew|Ding, Yi
PMID: 28260048
Journal: World J Gastroenterol. 2017 Feb 21;23(7):1189-1202.
Title: Dysregulation of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901.
Author: Xie, Xiao-Que|Zhao, Qi-Hong|Wang, Hua|Gu, Kang-Sheng
PMID: 28275299
Journal: Gastric Cancer. 2017 Nov;20(6):948-959.
Title: Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells.
Author: Chivu-Economescu, Mihaela|Dragu, Denisa L|Necula, Laura G|Matei, Lilia|Enciu, Ana Maria|Bleotu, Coralia|Diaconu, Carmen C
PMID: 28299464
Journal: J Exp Clin Cancer Res. 2017 Mar 21;36(1):45.
Title: MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2.
Author: Ding, Lei|Zhang, Shanyong|Xu, Mu|Zhang, Renwen|Sui, Pengcheng|Yang, Qing
PMID: 28327189
Journal: Gastroenterol Hepatol Bed Bench. 2017 Winter;10(1):21-28.
Title: Introducing crucial protein panel of gastric adenocarcinoma disease.
Author: Rezaei-Tavirani, Mostafa|Rezaei-Tavirani, Majid|Mansouri, Vahid|Mahdavi, Seyed Mohammad|Valizadeh, Reza|Rostami-Nejad, Mohammad|Zali, Mohammad Reza
PMID: 28331560
Journal: Neoplasia. 2017 Apr;19(4):374-382.
Title: E3 Ubiquitin Ligase Cbl-b Prevents Tumor Metastasis by Maintaining the Epithelial Phenotype in Multiple Drug-Resistant Gastric and Breast Cancer Cells.
Author: Xu, Ling|Zhang, Ye|Qu, Xiujuan|Che, Xiaofang|Guo, Tianshu|Cai, Ying|Li, Aodi|Li, Danni|Li, Ce|Wen, Ti|Fan, Yibo|Hou, Kezuo|Ma, Yanju|Hu, Xuejun|Liu, Yunpeng
PMID: 28334634
Journal: Mol Med Rep. 2017 May;15(5):3055-3061.
Title: Reduction of miR1323p contributes to gastric cancer proliferation by targeting MUC13.
Author: He, Liang|Qu, Linlin|Wei, Lijing|Chen, Yan|Suo, Jian
PMID: 28339011
Journal: Int J Oncol. 2017 May;50(5):1501-1512.
Title: FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Author: Huang, Tingting|Wang, Lei|Liu, Dian|Li, Piao|Xiong, Huihua|Zhuang, Liang|Sun, Li|Yuan, Xianglin|Qiu, Hong
PMID: 28339036
Journal: Acta Pharmacol Sin. 2017 Jul;38(7):1048-1058.
Title: Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment.
Author: Jiang, Xiao-Yan|Zhu, Xiao-Song|Xu, Hong-Ya|Zhao, Zhong-Xi|Li, Si-Ying|Li, Shan-Zhong|Cai, Jian-Hua|Cao, Ji-Min
PMID: 28344324
Journal: Sci Rep. 2017 Mar 27;7:45275.
Title: Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3beta activation.
Author: Li, Can|Zhang, Jie|Wu, Hao|Li, Lili|Yang, Caiting|Song, Shushu|Peng, Peike|Shao, Miaomiao|Zhang, Mingming|Zhao, Junjie|Zhao, Ran|Wu, Weicheng|Ruan, Yuanyuan|Wang, Lan|Gu, Jianxin
PMID: 28345638
Journal: Oncol Lett. 2017 Feb;13(2):655-660.
Title: Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells.
Author: Chen, Zhengrong|He, Tengfei|Zhao, Kui|Xing, Chungen
PMID: 28356942
Journal: Cancer Invest. 2017 May 28;35(5):289-300.
Title: Calycosin Enhances Some Chemotherapeutic Drugs Inhibition of Akt Signaling Pathway in Gastric Cells.
Author: Zhou, Lixia|Wu, Yueming|Guo, Yang|Li, Yanjun|Li, Na|Yang, Yi|Qin, Xueyun
PMID: 28368679
Journal: Arch Toxicol. 2017 Oct;91(10):3341-3364.
Title: Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.
Author: Chang, Chia-Ting|Hseu, You-Cheng|Thiyagarajan, Varadharajan|Lin, Kai-Yuan|Way, Tzong-Der|Korivi, Mallikarjuna|Liao, Jiuun-Wang|Yang, Hsin-Ling
PMID: 28374157
Journal: Gastric Cancer. 2017 Nov;20(6):960-969.
Title: Expression and function of Uc.160+, a transcribed ultraconserved region, in gastric cancer.
Author: Honma, Ririno|Goto, Keisuke|Sakamoto, Naoya|Sekino, Yohei|Sentani, Kazuhiro|Oue, Naohide|Yasui, Wataru
PMID: 28382457
Journal: Oncotarget. 2017 May 23;8(21):34516-34524.
Title: NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization.
Author: Sui, Hong|Wang, Kaibing|Xie, Rui|Li, Xi|Li, Kunpeng|Bai, Yuxian|Wang, Xishan|Bai, Bin|Chen, Dan|Li, Jiazhuang|Shen, Baozhong
PMID: 28388537
Journal: Oncotarget. 2017 Apr 25;8(17):29067-29079.
Title: A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer.
Author: Sun, Zu-Jun|Wu, Yi|Hou, Wei-Hua|Wang, Yu-Xiong|Yuan, Qing-Yun|Wang, Hui-Jie|Yu, Min
PMID: 28404966
Journal: BMC Cancer. 2017 Apr 14;17(1):268.
Title: Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer.
Author: Xing, Xiangbin|Cai, Weibin|Ma, Sanmei|Wang, Yongfei|Shi, Huijuan|Li, Ming|Jiao, Jinxia|Yang, Yang|Liu, Longshan|Zhang, Xiangliang|Chen, Minhu
PMID: 28407749
Journal: J Exp Clin Cancer Res. 2017 Apr 13;36(1):53.
Title: Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells.
Author: Zheng, Peiming|Chen, Lei|Yuan, Xiangliang|Luo, Qin|Liu, Yi|Xie, Guohua|Ma, Yanhui|Shen, Lisong
PMID: 28407783
Journal: Oncotarget. 2017 Jun 13;8(24):38389-38398.
Title: Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer.
Author: Kim, Hyo Song|Lee, Hanna|Shin, Su-Jin|Beom, Seung-Hoon|Jung, Minkyu|Bae, Sujin|Lee, Eun Young|Park, Kyu Hyun|Choi, Yoon Young|Son, Taeil|Kim, Hyoung-Il|Cheong, Jae-Ho|Hyung, Woo Jin|Park, Jun Chul|Shin, Sung Kwan|Lee, Sang Kil|Lee, Yong Chan|Koom, Woong S
PMID: 28418920
Journal: Molecules. 2017 Apr 17;22(4). pii: molecules22040628.
Title: Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells.
Author: Zhang, Lei|Wang, Jing|Liu, Lai|Zheng, Chengyue|Wang, Yang
PMID: 28420180
Journal: Oncotarget. 2017 Mar 28;8(13):22059-22075.
Title: Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Author: Liu, Fang|Zhang, Yuan|Men, Tingting|Jiang, Xingyue|Yang, Chunhua|Li, He|Wei, Xiaodan|Yan, Dong|Feng, Gangming|Yang, Jianke|Bergquist, Jonas|Wang, Bin|Jiang, Wenguo|Mi, Jia|Tian, Geng
PMID: 28423550
Journal: Oncotarget. 2017 Apr 4;8(14):23155-23166.
Title: Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer.
Author: Pei, Yao-Fei|Zhang, Ya-Jing|Lei, Yao|Wu, Ding-Wei|Ma, Tong-Hui|Liu, Xi-Qiang
PMID: 28423564
Journal: Oncotarget. 2017 Jun 13;8(24):39280-39295.
Title: The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer.
Author: Yu, Wei-Wei|Jiang, Hong|Zhang, Cun-Tai|Peng, Yang
PMID: 28424413
Journal: Oncogenesis. 2017 Apr 24;6(4):e323.
Title: TCRP1 promotes NIH/3T3 cell transformation by over-activating PDK1 and AKT1.
Author: Wang, C|Liu, H|Qiu, Q|Zhang, Z|Gu, Y|He, Z
PMID: 28436990
Journal: Dig Dis Sci. 2017 Aug;62(8):2004-2010.
Title: Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Apoptosis of Gastric Cancer Cells via PTEN/p-AKT Pathway.
Author: Guo, Jun-Qiang|Li, Shi-Jie|Guo, Guo-Xiao
PMID: 28451917
Journal: Oncol Lett. 2017 Apr;13(4):2133-2140.
Title: Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway.
Author: Jiao, Shuhua|Li, Nuo|Cai, Shuang|Guo, Haimei|Wen, Yanhui
PMID: 28454373
Journal: J Exp Clin Cancer Res. 2017 May 3;36(1):61.
Title: Retraction Note: MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling.
Author: Chu, Shao-Jun|Wang, Ge|Zhang, Peng-Fei|Zhang, Rui|Huang, Yan-Xia|Lu, Yun-Min|Da, Wei|Sun, Qun|Zhang, Jing|Zhu, Jin-Shui
PMID: 28468640
Journal: J Ethnopharmacol. 2017 Jun 9;205:147-157.
Title: Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer.
Author: Wang, Haibo|Tao, Lide|Ni, Tengyang|Gu, Hao|Jin, Feng|Dai, Xiaojun|Feng, Jun|Ding, Yanbing|Xiao, Weiming|Guo, Shiyu|Hisamitsu, Tadashi|Qian, Yayun|Liu, Yanqing
PMID: 28476678
Journal: Phytomedicine. 2017 May 15;28:10-18.
Title: Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.
Author: Li, Chuan|Wang, Yihai|Wang, Chunhua|Yi, Xiaomin|Li, Mingya|He, Xiangjiu
PMID: 28478808
Journal: Oncol Rep. 2017 Jun;37(6):3459-3466.
Title: Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells.
Author: Li, Wei|Zhou, Ying|Yang, Jin|Li, Haining|Zhang, Huanhuan|Zheng, Ping
PMID: 28498433
Journal: Oncol Rep. 2017 Jun;37(6):3590-3596.
Title: MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.
Author: Qiu, Yun-Tan|Wang, Wen-Jun|Zhang, Bing|Mei, Li-Li|Shi, Zhi-Zhou
PMID: 28498460
Journal: Cell Signal. 2017 Aug;36:222-229.
Title: Inhibition of cell proliferation and induction of autophagy by KDM2B/FBXL10 knockdown in gastric cancer cells.
Author: Zhao, Erhu|Tang, Chunling|Jiang, Xiaolan|Weng, Xiong|Zhong, Xiaoxia|Zhang, Dunke|Hou, Jianbing|Wang, Feng|Huang, Mengying|Cui, Hongjuan
PMID: 28506929
Journal: Oncotarget. 2017 Jul 11;8(28):45793-45806.
Title: Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance.
Author: Liu, Wenhu|Chang, Jinxia|Liu, Mingwei|Yuan, Jiangbei|Zhang, Jinqiang|Qin, Jun|Xia, Xuefeng|Wang, Yi
PMID: 28507275
Journal: J Surg Res. 2017 May 15;212:195-204.
Title: Analysis of PIK3CA mutations and PI3K pathway proteins in advanced gastric cancer.
Author: Ito, Chie|Nishizuka, Satoshi S|Ishida, Kazuyuki|Uesugi, Noriyuki|Sugai, Tamotsu|Tamura, Gen|Koeda, Keisuke|Sasaki, Akira
PMID: 28550907
Journal: Cell Death Dis. 2017 Jun 1;8(6):e2839.
Title: Long noncoding RNA UCA1 induced by SP1 promotes cell proliferation via recruiting EZH2 and activating AKT pathway in gastric cancer.
Author: Wang, Zhen-Qiang|Cai, Qiang|Hu, Lei|He, Chang-Yu|Li, Jian-Fang|Quan, Zhi-Wei|Liu, Bing-Ya|Li, Chen|Zhu, Zheng-Gang
PMID: 28569779
Journal: Sci Rep. 2017 Jun 6;7(1):2886.
Title: PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.
Author: Wang, Chao|Jiang, Jinling|Ji, Jun|Cai, Qu|Chen, Xuehua|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 28588255
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Oncol Lett. 2017 Jun;13(6):4701-4707.
Title: miR-200b inhibits CD133(+) glioma cells by targeting the AKT pathway.
Author: Liu, Aiqun|Yu, Qingyun|Peng, Zhongxing|Huang, Yeqing|Diao, Shengpeng|Cheng, Jing|Wang, Wentao|Hong, Mingfan
PMID: 28599471
Journal: Biochemistry (Mosc). 2017 Jun;82(6):707-714.
Title: MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells.
Author: Feng, Jing|Wang, Xiaojuan|Zhu, Weihua|Chen, Si|Feng, Changwei
PMID: 28601080
Journal: Mol Med Rep. 2017 Aug;16(2):2318-2324.
Title: Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK.
Author: Zhang, Xue-Song|Hu, Yan-Hua|Gao, Hong-Yu|Lan, Xiu-Wen|Xue, Ying-Wei
PMID: 28627671
Journal: Br J Cancer. 2017 Aug 8;117(4):525-534.
Title: MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer.
Author: Zhang, P|Tang, W M|Zhang, H|Li, Y Q|Peng, Y|Wang, J|Liu, G N|Huang, X T|Zhao, J J|Li, G|Li, A M|Bai, Y|Chen, Y|Ren, Y X|Li, G X|Wang, Y D|Liu, S D|Wang, J D
PMID: 28632723
Journal: Biochem Biophys Res Commun. 2017 Sep 23;491(3):821-826.
Title: S-allylmercaptocysteine suppresses the growth of human gastric cancer xenografts through induction of apoptosis and regulation of MAPK and PI3K/Akt signaling pathways.
Author: Zhu, Xiaosong|Jiang, Xiaoyan|Li, Ang|Sun, Yueyue|Liu, Yan|Sun, Xiao|Feng, Xiuli|Li, Siying|Zhao, Zhongxi
PMID: 28642133
Journal: Tumour Biol. 2017 Jun;39(6):1010428317704820.
Title: Gankyrin promotes the proliferation of gastric cancer and is associated with chemosensitivity.
Author: Zeng, Yue-Can|Sun, Dan|Li, Wen-Hui|Zhao, Jing|Xin, Yan
PMID: 28653901
Journal: Tumour Biol. 2017 Jul;39(7):1010428317712617.
Title: The Wnt/beta-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation.
Author: Song, Yue|Li, Zhao-Xia|Liu, Xi|Wang, Rui|Li, Li-Wei|Zhang, Qingyu
PMID: 28671020
Journal: Int J Oncol. 2017 Sep;51(3):801-811.
Title: Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/beta-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer.
Author: Xiang, Shili|Xiang, Tingxiu|Xiao, Qian|Li, Yunhai|Shao, Bianfei|Luo, Tao
PMID: 28677721
Journal: Oncol Rep. 2017 Sep;38(3):1733-1741.
Title: Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer.
Author: Yuan, Xiaoning|Zhang, Te|Zheng, Xin|Zhang, Yunfei|Feng, Tingting|Liu, Pengfei|Sun, Zhiting|Qin, Shanshan|Liu, Xuewen|Zhang, Liang|Song, Jie|Liu, Ying
PMID: 28677734
Journal: FEBS Open Bio. 2017 May 24;7(7):905-914.
Title: miR-944 inhibits metastasis of gastric cancer by preventing the epithelial-mesenchymal transition via MACC1/Met/AKT signaling.
Author: Pan, Tao|Chen, Wenjun|Yuan, Xiaoming|Shen, Jun|Qin, Chuan|Wang, Linbo
PMID: 28680805
Journal: Int J Oncol. 2017 Sep;51(3):967-974.
Title: Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling.
Author: Lee, Harry|Saini, Nipun|Parris, Amanda B|Zhao, Ming|Yang, Xiaohe
PMID: 28713919
Journal: Int J Oncol. 2017 Sep;51(3):867-876.
Title: MicroRNA-379 inhibits metastasis and epithelial-mesenchymal transition via targeting FAK/AKT signaling in gastric cancer.
Author: Xu, Meizhong|Qin, Shui|Cao, Fan|Ding, Shi|Li, Mengnan
PMID: 28713929
Journal: Zhonghua Zhong Liu Za Zhi. 2017 Jul 23;39(7):490-496.
Title: [Curcumin induces apoptosis and protective autophagy in human gastric cancer cells with different degree of differentiation].
Author: Li, W|Zhou, Y|Yang, J|Zhang, H H|Zhao, S L|Zhang, T|Huo, J|Zheng, P
PMID: 28728293
Journal: Oncol Rep. 2017 Sep;38(3):1806-1814.
Title: SMURF1 promotes the proliferation, migration and invasion of gastric cancer cells.
Author: Tao, Youmao|Sun, Caixia|Zhang, Tao|Song, Yan
PMID: 28731194
Journal: Cell Physiol Biochem. 2017;42(4):1701-1711.
Title: MicroRNA-302b-3p Suppresses Cell Proliferation Through AKT Pathway by Targeting IGF-1R in Human Gastric Cancer.
Author: Guo, Bo|Zhao, Zhenghao|Wang, Zhen|Li, Qian|Wang, Xiaofei|Wang, Wenjing|Song, Tusheng|Huang, Che
PMID: 28743112
Journal: Eur Rev Med Pharmacol Sci. 2017 Jul;21(3 Suppl):33-37.
Title: Research on the mechanism of HP mediated PI3K/AKT/GSK3beta pathways in gastric cancer.
Author: Geng, W|Zhang, H-Y
PMID: 28745795
Journal: Oncotarget. 2017 Jul 18;8(29):48526.
Title: Correction: Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer.
Author: Pei, Yao-Fei|Zhang, Ya-Jing|Lei, Yao|Wu, Ding-Wei|Ma, Tong-Hui|Liu, Xi-Qiang
PMID: 28753909
Journal: Oncol Lett. 2017 Aug;14(2):2103-2110.
Title: CXCL12/SDF-1alpha induces migration via SRC-mediated CXCR4-EGFR cross-talk in gastric cancer cells.
Author: Cheng, Yu|Qu, Jinglei|Che, Xiaofang|Xu, Ling|Song, Na|Ma, Yanju|Gong, Jing|Qu, Xiujuan|Liu, Yunpeng
PMID: 28781651
Journal: Theriogenology. 2017 Nov;103:162-168.
Title: ERas is constitutively expressed in full term placenta of pregnant cows.
Author: Roperto, Sante|Russo, Valeria|Urraro, Chiara|Restucci, Brunella|Corrado, Federica|De Falco, Francesca|Roperto, Franco
PMID: 28787666
Journal: Oncol Lett. 2017 Aug;14(2):1993-2000.
Title: Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer.
Author: Lu, Xueying|Li, Yanhong|Li, Xiaobo|Aisa, Haji Akber
PMID: 28789432
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2017 Aug 20;37(8):1085-1091.
Title: [Quinalizarin induces apoptosis in gastric cancer AGS cells via MAPK and Akt signaling pathway].
Author: Liu, Chang|Luo, Ying-Hua|Piao, Xian-Ji|Wang, Yue|Meng, Ling-Qi|Wang, Hao|Wang, Jia-Ru|Zhang, Yi|Li, Jin-Qian|Jin, Cheng-Hao
PMID: 28801290
Journal: J Cancer. 2017 Jul 1;8(10):1733-1743.
Title: In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Author: Klameth, Lukas|Rath, Barbara|Hamilton, Gerhard
PMID: 28819369
Journal: Eur J Pharmacol. 2017 Nov 5;814:207-215.
Title: Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Author: Wang, Guijun|Lu, Meili|Yao, Yusheng|Wang, Jing|Li, Juan
PMID: 28847482
Journal: Cell Physiol Biochem. 2017;43(1):195-208.
Title: A Comparative Proteomic Analysis of Erinacine A's Inhibition of Gastric Cancer Cell Viability and Invasiveness.
Author: Kuo, Hsing-Chun|Kuo, Yur-Ren|Lee, Kam-Fai|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Hsieh, Yung-Yu|Lee, Ko-Chao|Kuo, Hsiang-Lan|Lee, Li-Ya|Chen, Wan-Ping|Chen, Chin-Chu|Tung, Shui-Yi
PMID: 28854418
Journal: Cancer Med. 2017 Oct;6(10):2331-2346.
Title: CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway.
Author: Sun, Yi|Jiang, Yingming|Huang, Jintuan|Chen, Hao|Liao, Yi|Yang, Zuli
PMID: 28857517
Journal: Onco Targets Ther. 2017 Aug 22;10:4153-4159.
Title: AKT inhibition is an effective treatment strategy in ARID1A-deficient gastric cancer cells.
Author: Lee, Dakeun|Yu, Eun Ji|Ham, In-Hye|Hur, Hoon|Kim, You-Sun
PMID: 28860825
Journal: BMC Cancer. 2017 Sep 6;17(1):626.
Title: ERp29 controls invasion and metastasis of gastric carcinoma by inhibition of epithelial-mesenchymal transition via PI3K/Aktsignaling pathway.
Author: Ye, Jianxin|Huang, Jinsheng|Xu, Jie|Huang, Qiang|Wang, Jinzhou|Zhong, Wenjing|Lin, Xinjian|Li, Yun|Lin, Xu
PMID: 28874138
Journal: Oncotarget. 2017 May 10;8(31):51177-51189.
Title: Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway.
Author: Yin, Kai|Wang, Linjun|Zhang, Xuan|He, Zhongyuan|Xia, Yiwen|Xu, Jianghao|Wei, Song|Li, Bowen|Li, Zheng|Sun, Guangli|Li, Qing|Xu, Hao|Xu, Zekuan
PMID: 28881639
Journal: Oncotarget. 2017 Apr 29;8(32):52584-52593.
Title: siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells.
Author: Yuan, Heng-Heng|Yang, Ying-Nan|Zhou, Jian-Hua|Li, Yan-Jing|Wang, Li-Ying|Qin, Jun-Wei|Liu, Tao|Li, Zhen-Zhen|Zhou, Qing-Xin|Wei, Xiao-Li|Zhang, Ting-Ting|Huang, Peng|Zhang, Wen-Jie|Liu, Lei|Du, Xiao-Xue|Han, Yu
PMID: 28881753
Journal: Anticancer Drugs. 2017 Nov;28(10):1141-1149.
Title: Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer.
Author: Jin, Junfei|Xiong, Ying|Cen, Bo
PMID: 28885267
Journal: Sci Rep. 2017 Sep 11;7(1):11127.
Title: Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines.
Author: Baba, Koichi|Kitajima, Yoshihiko|Miyake, Shuusuke|Nakamura, Jun|Wakiyama, Kota|Sato, Hirofumi|Okuyama, Keiichiro|Kitagawa, Hiroshi|Tanaka, Tomokazu|Hiraki, Masatsugu|Yanagihara, Kazuyoshi|Noshiro, Hirokazu
PMID: 28894280
Journal: Cancer Cell Int. 2017 Sep 13;17:81.
Title: SNP rs3202538 in 3'UTR region of ErbB3 regulated by miR-204 and miR-211 promote gastric cancer development in Chinese population.
Author: Shi, Yaxiang|Chen, Xuan|Xi, Biao|Yu, Xiaowen|Ouyang, Jun|Han, Chunxia|Qin, Yucheng|Wu, Defeng|Shen, Hong
PMID: 28924391
Journal: Oncotarget. 2017 Apr 10;8(35):59878-59888.
Title: p-Akt as a potential poor prognostic factor for gastric cancer: a systematic review and meta-analysis.
Author: Cao, Fang|Zhang, Cong|Han, Wei|Gao, Xiao-Jiao|Ma, Jun|Hu, Yong-Wei|Gu, Xing|Ding, Hou-Zhong|Zhu, Li-Xia|Liu, Qin
PMID: 28938690
Journal: Oncol Res. 2017 Sep 26.
Title: Downregulation of MicroRNA-147 Inhibits Cell Proliferation and Increases the Chemosensitivity of Gastric Cancer Cells to 5-Fluorouracil by Directly Targeting PTEN.
Author: Shen, Jianjun|Niu, Weina|Zhang, Hongbo|Jun, Ma|Zhang, Hongyan
PMID: 28950928
Journal: Cancer Res. 2017 Dec 1;77(23):6499-6512.
Title: Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel.
Author: Xie, Rui|Xu, Jingyu|Xiao, Yufeng|Wu, Jilin|Wan, Hanxing|Tang, Bo|Liu, Jingjing|Fan, Yahan|Wang, Suming|Wu, Yuyun|Dong, Tobias Xiao|Zhu, Michael X|Carethers, John M|Dong, Hui|Yang, Shiming
PMID: 28951460
Journal: Virchows Arch. 2017 Dec;471(6):743-751.
Title: HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer.
Author: Xu, Hao|Miao, Zhi-Feng|Wang, Zhen-Ning|Zhao, Ting-Ting|Xu, Ying-Ying|Song, Yong-Xi|Huang, Jin-Yu|Zhang, Jun-Yan|Liu, Xing-Yu|Wu, Jian-Hua|Xu, Hui-Mian
PMID: 28963677
Journal: Am J Transl Res. 2017 Sep 15;9(9):4317-4330. eCollection 2017.
Title: Targeting mTORC2 component rictor inhibits cell proliferation and promotes apoptosis in gastric cancer.
Author: Bian, Yu-Hai|Xu, Jia|Zhao, Wen-Yi|Zhang, Zi-Zhen|Tu, Lin|Cao, Hui|Zhang, Zhi-Gang
PMID: 28979705
Journal: Cell Mol Biol (Noisy-le-grand). 2017 Sep 30;63(9):18-23.
Title: FAM196B acts as oncogene and promotes proliferation of gastric cancer cells through AKT signaling pathway.
Author: Zhang, J|Tong, D D|Xue, M|Jiang, Q Y|Wang, X F|Yang, P B|Ni, L|Zhao, L Y|Huang, C
PMID: 28980917
Journal: Tumour Biol. 2017 Oct;39(10):1010428317722070.
Title: TWIST mediates resistance to paclitaxel by regulating Akt and Bcl-2 expression in gastric cancer cells.
Author: Kwon, Chae Hwa|Park, Hye Ji|Choi, Yuri|Won, Yeo Jin|Lee, Seon Jin|Park, Do Youn
PMID: 28982309
Journal: Mol Med Rep. 2017 Dec;16(6):8977-8982.
Title: Antitumor effects of bakuchiol on human gastric carcinoma cell lines are mediated through PI3K/AKT and MAPK signaling pathways.
Author: Lv, Long|Liu, Bo
PMID: 28990045
Journal: Dig Dis Sci. 2017 Dec;62(12):3415-3425.
Title: PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3beta/beta-Catenin Signaling Pathway in Human Gastric Cancer.
Author: Ma, Jingjing|Guo, Xufeng|Zhang, Jixiang|Wu, Dandan|Hu, Xue|Li, Jiao|Lan, Qingzhi|Liu, Ya|Dong, Weiguo
PMID: 29030742
Journal: Biomed Pharmacother. 2017 Dec;96:634-641.
Title: MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer.
Author: Xu, Song|Ge, Jingping|Zhang, Zhengyu|Zhou, Wenquan
PMID: 29035829
Journal: Mol Med Rep. 2017 Dec;16(6):9685-9691.
Title: Clinical implications of progranulin in gastric cancer and its regulation via a positive feedback loop involving AKT and ERK signaling pathways.
Author: Yang, Dong|Li, Ruidong|Wang, Huili|Wang, Junye|Han, Lei|Pan, Lihua|Li, Xueqin|Kong, Qingli|Wang, Guijuan|Su, Xiujun
PMID: 29039535
Journal: Oncotarget. 2017 Jul 22;8(41):69888-69905.
Title: Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients.
Author: Kim, Yoonjung|Cho, Mee-Yon|Kim, Juwon|Kim, Sung Nam|Oh, Seoung Chul|Lee, Kyung-A
PMID: 29050249
Journal: Oncotarget. 2017 Aug 9;8(41):70271-70280.
Title: Identification of core genes and outcome in gastric cancer using bioinformatics analysis.
Author: Sun, Chenhua|Yuan, Qi|Wu, Dongdong|Meng, Xiaohu|Wang, Baolin
PMID: 29050278
Journal: Cancer Biomark. 2017 Dec 12;21(1):105-116.
Title: MicroRNA-937 inhibits cell proliferation and metastasis in gastric cancer cells by downregulating FOXL2.
Author: Yu, Liang|Chen, Jun|Liu, Yu|Zhang, Zengfeng|Duan, Shaobin
PMID: 29060929
Journal: Oncotarget. 2017 May 11;8(42):71630-71641.
Title: MGr1-Antigen/37 kDa laminin receptor precursor promotes cellular prion protein induced multi-drug-resistance of gastric cancer.
Author: Luo, Guanhong|Wang, Weijie|Wu, Qiong|Lu, Yuanyuan|Su, Tao|Gu, Nan|Li, Kai|Wang, Jingbo|Du, Rui|Zhao, Xiaodi|Li, Xiaohua|Fan, Rui|Zhang, Hongbo|Nie, Yongzhan|Zhou, Xinmin|Shi, Yongquan|Liang, Jie|Wang, Xin|Fan, Daiming
PMID: 29069734
Journal: Oncotarget. 2017 May 13;8(42):71725-71735.
Title: B7-H3 promotes gastric cancer cell migration and invasion.
Author: Li, Yecheng|Yang, Xiaodong|Wu, Yong|Zhao, Kui|Ye, Zhenyu|Zhu, Junjia|Xu, Xiaohui|Zhao, Xin|Xing, Chungen
PMID: 29069741
Journal: Oncotarget. 2017 Aug 7;8(42):72157-72166.
Title: The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer.
Author: Wang, Hong|Wang, Chunlei|Tian, Wenling|Yao, Yanfen
PMID: 29069776
Journal: Int J Oncol. 2017 Dec;51(6):1860-1868.
Title: Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines.
Author: Wang, Ya-Mei|Gu, Meng-Li|Meng, Fan-Sheng|Jiao, Wen-Rui|Zhou, Xin-Xin|Yao, Hang-Ping|Ji, Feng
PMID: 29075795
Journal: Iran J Basic Med Sci. 2017 Sep;20(9):990-995.
Title: Apatinib has anti-tumor effects and induces autophagy in colon cancer cells.
Author: Lu, Wu|Ke, He|Qianshan, Ding|Zhen, Wang|Guoan, Xiang|Honggang, Yu
PMID: 29085592
Journal: Dig Dis Sci. 2017 Dec;62(12):3426-3437.
Title: The GAS5/miR-222 Axis Regulates Proliferation of Gastric Cancer Cells Through the PTEN/Akt/mTOR Pathway.
Author: Li, Yanhua|Gu, Junjiao|Lu, Hong
PMID: 29098549
Journal: Molecules. 2017 Nov 3;22(11). pii: molecules22111886.
Title: Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS.
Author: Tian, Shuang|Yu, Hongdan
PMID: 29099789
Journal: Oncotarget. 2017 Jul 18;8(44):76279-76289.
Title: Downregulation of HADH promotes gastric cancer progression via Akt signaling pathway.
Author: Shen, Congcong|Song, Yao-Hua|Xie, Yufeng|Wang, Xiaoxiao|Wang, Yunliang|Wang, Chao|Liu, Songbai|Xue, Sheng-Li|Li, Yangxin|Liu, Bin|Tang, Zaixiang|Chen, Weichang|Song, Jenny|Amin, Hesham M|Zhou, Jin
PMID: 29100311
Journal: Oncotarget. 2017 Aug 12;8(45):78757-78766.
Title: ERp29 inhibits tumorigenicity by suppressing epithelial mesenchymal transition in gastric cancer.
Author: Wu, Jing|Yang, Yuanyan|Gao, Shenshen|Jiang, Hong|Wang, Xin-Qiong|Xiao, Yuan|Chen, Xue-Hua|Li, Pu|Xu, Chun-Di
PMID: 29108263
Journal: Oncotarget. 2017 Aug 12;8(47):82981-82990.
Title: Mcl-1 stabilization confers resistance to taxol in human gastric cancer.
Author: Shuang, Wu|Hou, Lili|Zhu, Yan|Li, Qun|Hu, Wanglai
PMID: 29137317
Journal: Oncotarget. 2017 Sep 15;8(48):84285-84299.
Title: Expression of the beta3 subunit of Na(+)/K(+)-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway.
Author: Li, Li|Feng, Ru|Xu, Qian|Zhang, Feiyue|Liu, Tong|Cao, Jiang|Fei, Sujuan
PMID: 29137423
Journal: Oncol Lett. 2017 Nov;14(5):5409-5417.
Title: Combined aspirin and apatinib treatment suppresses gastric cancer cell proliferation.
Author: Zhang, Wei|Tan, Yongsheng|Ma, Heping
PMID: 29142602
Journal: Oncotarget. 2017 Sep 8;8(49):85926-85939.
Title: Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene.
Author: Ma, Jingjing|Hu, Xue|Li, Jiao|Wu, Dandan|Lan, Qingzhi|Wang, Qian|Tian, Shan|Dong, Weiguo
PMID: 29156767
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Oct;33(10):1354-1359.
Title: [Knockdown of AKT1 gene enhances the sensitivity of gastric cancer xenografts of nude mice to doxorubicin].
Author: Zhou, Wei|Fu, Xueqiong|Yu, Honggang
PMID: 29169420
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Nov 28;42(11):1241-1247.
Title: [IL-6 promotes gastric cancer cell proliferation and EMT through regulating miR-152/PIK3R3 pathway].
Author: Sun, Jie|Fu, Lifang
PMID: 29187649
Journal: Oncotarget. 2017 Jun 28;8(53):90948-90958.
Title: PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer.
Author: Kim, Ji-Won|Lee, Hye Seung|Nam, Kyung Han|Ahn, Soyeon|Kim, Jin Won|Ahn, Sang-Hoon|Park, Do Joong|Kim, Hyung-Ho|Lee, Keun-Wook
PMID: 29207615
Journal: Oncotarget. 2017 Jul 17;8(55):93476-93491.
Title: Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway.
Author: Li, Chengyun|Liang, Geyu|Yang, Sheng|Sui, Jing|Yao, Wenzhuo|Shen, Xian|Zhang, Yanqiu|Peng, Hui|Hong, Weiwei|Xu, Siyi|Wu, Wenjuan|Ye, Yancheng|Zhang, Zhiyi|Zhang, Wenhua|Yin, Lihong|Pu, Yuepu
PMID: 29212166
Journal: Anticancer Drugs. 2017 Dec 5.
Title: Mangiferin prevents the growth of gastric carcinoma by blocking the PI3K-Akt signalling pathway.
Author: Du, Min|Wen, Gang|Jin, Juan|Chen, Yuanguang|Cao, Jun|Xu, Aman
PMID: 29215373
Journal: Med Sci Monit. 2017 Dec 9;23:5834-5843.
Title: DNA Methylation-Mediated Silencing of Regenerating Protein 1 Alpha (REG1A) Affects Gastric Cancer Prognosis.
Author: Qiu, Yan-Song|Liao, Guang-Jun|Jiang, Ning-Ning
PMID: 29222406
Journal: J Biosci. 2017 Dec;42(4):547-554.
Title: Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway.
Author: Feng, Li-Min|Wang, Xue-Feng|Huang, Qing-Xian
PMID: 29229873
Journal: BMC Cancer. 2017 Dec 12;17(1):841.
Title: Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients.
Author: Cao, Guo-Dong|Chen, Ke|Chen, Bo|Xiong, Mao-Ming
PMID: 29233126
Journal: BMC Cancer. 2017 Dec 13;17(1):845.
Title: Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis.
Author: Keller, Simone|Kneissl, Julia|Grabher-Meier, Verena|Heindl, Stefan|Hasenauer, Jan|Maier, Dieter|Mattes, Julian|Winter, Peter|Luber, Birgit
PMID: 29237412
Journal: J Transl Med. 2017 Dec 13;15(1):253.
Title: Gimatecan exerts potent antitumor activity against gastric cancer in vitro and in vivo via AKT and MAPK signaling pathways.
Author: Chen, Zuhua|Liu, Zhentao|Huang, Wenwen|Li, Zhongwu|Zou, Jianling|Wang, Jingyuan|Lin, Xiaoting|Li, Beifang|Chen, Dongshao|Hu, Yanting|Ji, Jiafu|Gao, Jing|Shen, Lin
PMID: 29237470
Journal: Eur Rev Med Pharmacol Sci. 2017 Dec;21(23):5392-5398.
Title: Long non-coding RNA CRNDE is a novel tumor promoter by modulating PI3K/AKT signal pathways in human gastric cancer.
Author: Du, D-X|Lian, D-B|Amin, B-H|Yan, W
PMID: 29243780
Journal: Oncotarget. 2017 Nov 1;8(59):100358-100370.
Title: Kruppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling.
Author: Wang, Chunmei|Li, Liang|Duan, Qiuhui|Wang, Qingqing|Chen, Jinlian
PMID: 29245984
Journal: J Exp Clin Cancer Res. 2017 Dec 28;36(1):194.
Title: LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway.
Author: Huang, Yanxia|Zhang, Jing|Hou, Lidan|Wang, Ge|Liu, Hui|Zhang, Rui|Chen, Xiaoyu|Zhu, Jinshui
PMID: 29282102
Journal: Oncotarget. 2017 Nov 11;8(62):105727-105734.
Title: MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines.
Author: Kim, Jung Eun|Kim, Youjin|Li, Gary|Kim, Seung Tae|Kim, Kyung|Park, Se Hoon|Park, Joon Oh|Park, Young Suk|Lim, Ho Yeong|Lee, Hyuk|Sohn, Tae Sung|Kim, Kyoung-Mee|Kang, Won Ki|Lee, Jeeyun
PMID: 29285287
Journal: World J Gastroenterol. 2017 Dec 21;23(47):8291-8299.
Title: Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing.
Author: Youssef, Omar|Sarhadi, Virinder|Ehsan, Homa|Bohling, Tom|Carpelan-Holmstrom, Monika|Koskensalo, Selja|Puolakkainen, Pauli|Kokkola, Arto|Knuutila, Sakari
PMID: 29307989
Journal: J BUON. 2017 Nov-Dec;22(6):1471-1476.
Title: Imperatorin shows selective antitumor effects in SGC-7901 human gastric adenocarcinoma cells by inducing apoptosis, cell cycle arrest and targeting PI3K/Akt/m-TOR signalling pathway.
Author: Am, J U|Gong, W J|Su, Y|Mou, Z B
PMID: 29332340
Journal: J BUON. 2017 Nov-Dec;22(6):1488-1493.
Title: Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.
Author: Qi, Lei|Sun, Kewen|Zhuang, Yun|Yang, Jing|Chen, Jianping
PMID: 29332342
Journal: Oncol Lett. 2017 Dec;14(6):7522-7528.
Title: Combination of cecropinXJ and LY294002 induces synergistic cytotoxicity, and apoptosis in human gastric cancer cells via inhibition of the PI3K/Akt signaling pathway.
Author: Xia, Li-Jie|Wu, Yan-Ling|Zhang, Fu-Chun
PMID: 29344198
Journal: Evid Based Complement Alternat Med. 2017;2017:3039450.
Title: Compound Wumei Powder Inhibits the Invasion and Metastasis of Gastric Cancer via Cox-2/PGE2-PI3K/AKT/GSK3beta/beta-Catenin Signaling Pathway.
Author: Ma, Nai-Xia|Sun, Wei|Wu, Jian|Liu, Shen-Lin|Weng, Lei|Liu, Yang-Qing|Pu, Wen-Xiu|Wu, Ting-Ting|Ding, Xue-Lian|Huang, Nan-Guang|Zheng, Pei-Qiu|Zou, Xi
PMID: 29358963
Journal: Oncotarget. 2017 Dec 9;8(69):113460-113471.
Title: Helicobacter pylori CagA protein activates Akt and attenuates chemotherapeutics-induced apoptosis in gastric cancer cells.
Author: Lan, Keng-Hsueh|Lee, Wei-Ping|Wang, Yu-Shan|Liao, Shi-Xian|Lan, Keng-Hsin
PMID: 29371922
Journal: J Cell Biochem. 2018 Jan;119(1):440-446.
Title: Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway.
Author: Pan, Haiyan|Li, Tao|Jiang, Yugang|Pan, Congcong|Ding, Yuanlin|Huang, Zhigang|Yu, Haibing|Kong, Danli
PMID: 28608528
Journal: Mol Cell Biochem. 2018 Mar;440(1-2):33-42.
Title: ARHGEF39 promotes gastric cancer cell proliferation and migration via Akt signaling pathway.
Author: Wang, Haixiao|Li, Miaomiao|Tao, Xiaobao|Qian, Yan|Chen, Linfang|Tao, Guoquan
PMID: 28871449
Journal: J Cell Physiol. 2018 Jun;233(6):4634-4642.
Title: Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling.
Author: Fu, Hongbing|Wang, Changming|Yang, Dejun|Wei, Ziran|Xu, Jiapeng|Hu, Zunqi|Zhang, Yu|Wang, Weimin|Yan, Ronglin|Cai, Qingping
PMID: 28926094
Journal: Mol Cancer Ther. 2018 Jan;17(1):232-242.
Title: Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3beta.
Author: Lau, Wen Min|Teng, Eileen|Huang, Kie Kyon|Tan, Jin Wei|Das, Kakoli|Zang, Zhijiang|Chia, Tania|Teh, Ming|Kono, Koji|Yong, Wei Peng|Shabbir, Asim|Tay, Amy|Phua, Niam Sin|Tan, Patrick|Chan, Shing Leng|So, Jimmy Bok Yan
PMID: 28978722
Journal: Cancer Lett. 2018 Jan 1;412:30-36.
Title: Complement C5a/C5aR pathway potentiates the pathogenesis of gastric cancer by down-regulating p21 expression.
Author: Chen, Jian|Li, Gui-Qing|Zhang, Li|Tang, Ming|Cao, Xu|Xu, Gui-Lian|Wu, Yu-Zhang
PMID: 29031586
Journal: Cell Biol Int. 2018 Mar;42(3):294-302.
Title: Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.
Author: Zhao, Lei|Li, Xin|Song, Na|Li, Aodi|Hou, Kezuo|Qu, Xiujuan|Che, Xiaofang|Liu, Yunpeng
PMID: 29052277
Journal: Int J Biol Macromol. 2018 Feb;107(Pt B):2620-2629.
Title: Knockdown of long non-coding RNA HOTAIR inhibits cisplatin resistance of gastric cancer cells through inhibiting the PI3K/Akt and Wnt/beta-catenin signaling pathways by up-regulating miR-34a.
Author: Cheng, Chuanyao|Qin, Yaguang|Zhi, Qiongjie|Wang, Jianjun|Qin, Changjiang
PMID: 29080815
Journal: Biochem Biophys Res Commun. 2018 Jan 1;495(1):928-934.
Title: miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH.
Author: Li, Lihua|Wang, Xiaojie|Li, Wei|Yang, Libo|Liu, Rui|Zeng, Rong|Wu, Yunhua|Shou, Tao
PMID: 29101039
Journal: Oncogene. 2018 Feb 22;37(8):1075-1085.
Title: CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2.
Author: Qi, M|Jiao, M|Li, X|Hu, J|Wang, L|Zou, Y|Zhao, M|Zhang, R|Liu, H|Mi, J|Zhang, L|Liu, L|Gong, Y|Han, B
PMID: 29106389
Journal: Mol Med Rep. 2018 Jan;17(1):602-611.
Title: MicroRNA-197 inhibits gastric cancer progression by directly targeting metadherin.
Author: Liao, Zhiwei|Li, Yue|Zhou, Yuanhang|Huang, Qi|Dong, Jian
PMID: 29115517
Journal: Oncol Rep. 2018 Jan;39(1):307-315.
Title: The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.
Author: Lian, Guodong|Li, Leping|Ye, Fei|Wang, Daguang|Liu, Jinglei|Shi, Yulong|Jing, Changqing|Suo, Jian|Zhang, David Y|Chen, Man
PMID: 29115543
Journal: Pathobiology. 2018;85(3):192-200.
Title: Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.
Author: Oue, Naohide|Yamamoto, Yuji|Oshima, Takashi|Asai, Ryuichi|Ishikawa, Akira|Uraoka, Naohiro|Sakamoto, Naoya|Sentani, Kazuhiro|Yasui, Wataru
PMID: 29131081
Journal: J Cell Biochem. 2018 Jun;119(6):4420-4434.
Title: Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k-Akt signaling pathway.
Author: Ao, Ran|Guan, Lin|Wang, Ying|Wang, Jia-Ni
PMID: 29143985
Journal: DNA Cell Biol. 2018 Jan;37(1):38-45.
Title: miR-21 Inhibitors Modulate Biological Functions of Gastric Cancer Cells via PTEN/PI3K/mTOR Pathway.
Author: Wang, Ping|Guan, Qunye|Zhou, Dongmei|Yu, Ze|Song, Yaobo|Qiu, Wensheng
PMID: 29185784
Journal: Hum Pathol. 2018 Feb;72:107-116.
Title: Nectin-4 promotes gastric cancer progression via the PI3K/AKT signaling pathway.
Author: Zhang, Yan|Chen, Peisheng|Yin, Wei|Ji, Ye|Shen, Qin|Ni, Qingfeng
PMID: 29208564
Journal: J Cell Biochem. 2018 Aug;119(8):6398-6407.
Title: NES1/KLK10 promotes trastuzumab resistance via activation of PI3K/AKT signaling pathway in gastric cancer.
Author: Tang, Laiqin|Long, Zhiguo|Zhao, Na|Feng, Guangjia|Guo, Xianzhi|Yu, Minghua
PMID: 29231994
Journal: Acta Pharmacol Sin. 2018 Apr;39(4):642-648.
Title: Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of raddeanin A against human breast cancer cells in vitro.
Author: Guan, Yi-di|Jiang, Shi-Long|Yu, Pian|Wen, Mei|Zhang, Yi|Xiao, Song-Shu|Xu, Xiao-Jun|Cheng, Yan
PMID: 29239350
Journal: Mol Med Rep. 2018 Mar;17(3):4003-4010.
Title: MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway.
Author: Li, Lihua|Zhu, Xiongjie|Shou, Tao|Yang, Libo|Cheng, Xiaozhen|Wang, Jinting|Deng, Lian|Zheng, Yanfang
PMID: 29257342
Journal: Cell Biol Int. 2018 Jul;42(7):781-793.
Title: Chk1 activation attenuates sensitivity of lapatinib in HER2-positive gastric cancer.
Author: Bai, Ming|Song, Na|Che, Xiaofang|Wang, Xiaoxun|Qu, Xiujuan|Liu, Yunpeng
PMID: 29271513
Journal: Biomed Pharmacother. 2018 Feb;98:416-423.
Title: F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT.
Author: Sun, Caixia|Tao, Youmao|Gao, Yongjian|Xia, Yufeng|Liu, Ying|Wang, Gang|Gu, Ye
PMID: 29278851
Journal: Cancer Biomark. 2018 Feb 14;21(3):731-741.
Title: EGFR and AKT1 overexpression are mutually exclusive and associated with a poor survival in resected gastric adenocarcinomas.
Author: Petrini, Iacopo|Lencioni, Monica|Vasile, Enrico|Fornaro, Lorenzo|Belluomini, Lorenzo|Pasquini, Giulia|Ginocchi, Laura|Caparello, Chiara|Musettini, Gianna|Vivaldi, Caterina|Caponi, Sara|Ricci, Sergio|Proietti, Agenese|Fontanini, Gabriella|Naccarato, Antoni
PMID: 29278885
Journal: Oncol Rep. 2018 Mar;39(3):1181-1190.
Title: Licochalcone A suppresses hexokinase 2-mediated tumor glycolysis in gastric cancer via downregulation of the Akt signaling pathway.
Author: Wu, Jian|Zhang, Xingxing|Wang, Yaohui|Sun, Qingmin|Chen, Min|Liu, Shenlin|Zou, Xi
PMID: 29286170
Journal: Med Sci Monit. 2018 Jan 7;24:149-160.
Title: Downregulation of Annexin A11 (ANXA11) Inhibits Cell Proliferation, Invasion, and Migration via the AKT/GSK-3beta Pathway in Gastric Cancer.
Author: Hua, Kelei|Li, Yong|Zhao, Qun|Fan, Liqiao|Tan, Bibo|Gu, Jianbin
PMID: 29306955
Journal: Sci Rep. 2018 Jan 10;8(1):397.
Title: Correlation of Gli1 and HER2 expression in gastric cancer: Identification of novel target.
Author: Shao, Xinyu|Kuai, Xiaoyi|Pang, Zhi|Zhang, Liping|Wu, Longyun|Xu, Lijuan|Zhou, Chunli
PMID: 29321573
Journal: J Hematol Oncol. 2018 Jan 15;11(1):9.
Title: The polycomb group protein EZH2 induces epithelial-mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter.
Author: Gan, Lu|Xu, Midie|Hua, Ruixi|Tan, Cong|Zhang, Jieyun|Gong, Yiwei|Wu, Zhenhua|Weng, Weiwei|Sheng, Weiqi|Guo, Weijian
PMID: 29335012
Journal: Cell Cycle. 2018;17(6):759-765.
Title: Long non-coding RNA GPR65-1 is up-regulated in gastric cancer and promotes tumor growth through the PTEN-AKT-slug signaling pathway.
Author: Li, Yansen|Shen, Zhanlong|Wang, Bo|Ye, Chunxiang|Lai, Zhiyong|Jiang, Hongpeng|Wang, Zhu|Jiang, Kewei|Ye, Yingjiang|Wang, Shan
PMID: 29336198
Journal: J Cancer. 2018 Jan 1;9(2):358-366.
Title: Clinical Significance of Glycoprotein Non-metastatic B and Its Association with EGFR/HER2 in Gastrointestinal Cancer.
Author: Tajima, Jesse Yu|Futamura, Manabu|Gaowa, Siqin|Mori, Ryutaro|Tanahashi, Toshiyuki|Tanaka, Yoshihiro|Matsuhashi, Nobuhisa|Takahashi, Takao|Yamaguchi, Kazuya|Miyazaki, Tatsuhiko|Yoshida, Kazuhiro
PMID: 29344282
Journal: Cell Death Dis. 2018 Jan 26;9(2):123.
Title: Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway.
Author: Chen, Dongshao|Lin, Xiaoting|Zhang, Cheng|Liu, Zhentao|Chen, Zuhua|Li, Zhongwu|Wang, Jingyuan|Li, Beifang|Hu, Yanting|Dong, Bin|Shen, Lin|Ji, Jiafu|Gao, Jing|Zhang, Xiaotian
PMID: 29374144
Journal: Anticancer Res. 2018 Feb;38(2):803-809.
Title: Autophagy Induced by Naftopidil Inhibits Apoptosis of Human Gastric Cancer Cells.
Author: Nakamura, Azumi|Matsunaga, Wataru|Gotoh, Akinobu
PMID: 29374705
Journal: FASEB J. 2018 May;32(5):2601-2614.
Title: Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy.
Author: Tsai, Chung-Ying|Chi, Hsiang-Cheng|Chi, Lang-Ming|Yang, Huang-Yu|Tsai, Ming-Ming|Lee, Kam-Fai|Huang, Hsiang-Wei|Chou, Li-Fang|Cheng, Ann-Joy|Yang, Chih-Wei|Wang, Chia-Siu|Lin, Kwang-Huei
PMID: 29401583
Journal: J Hematol Oncol. 2018 Feb 8;11(1):17.
Title: CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-kappaB-miR-21 pathways.
Author: Ni, Su-Jie|Zhao, Li-Qin|Wang, Xiao-Feng|Wu, Zhen-Hua|Hua, Rui-Xi|Wan, Chun-Hua|Zhang, Jie-Yun|Zhang, Xiao-Wei|Huang, Ming-Zhu|Gan, Lu|Sun, Hua-Lin|Dimri, Goberdhan P|Guo, Wei-Jian
PMID: 29422082
Journal: Oncol Lett. 2018 Jan;15(1):755-764.
Title: Association of mast cell infiltration with gastric cancer progression.
Author: Zhong, Bei|Li, Yu|Liu, Xiaodong|Wang, Dongsheng
PMID: 29422964
Journal: Am J Transl Res. 2018 Jan 15;10(1):304-314. eCollection 2018.
Title: Interaction between CD133 and PI3K-p85 promotes chemoresistance in gastric cancer cells.
Author: Song, Shuzheng|Pei, Guoqing|Du, Yaqiong|Wu, Jugang|Ni, Xiaochun|Wang, Shoulian|Jiang, Bojian|Luo, Meng|Yu, Jiwei
PMID: 29423015
Journal: Biomed Pharmacother. 2018 Apr;100:176-183.
Title: Astragalus polysaccharide enhanced antitumor effects of Apatinib in gastric cancer AGS cells by inhibiting AKT signalling pathway.
Author: Wu, Jun|Yu, Junxian|Wang, Jing|Zhang, Chenguang|Shang, Kun|Yao, Xiaojun|Cao, Bangwei
PMID: 29428665
Journal: Oncol Lett. 2018 Mar;15(3):3185-3191.
Title: Interference of P-REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin.
Author: Ai, Yaowei|Zhou, Qiaohui|Li, Ling|Pan, Zhihong|Guo, Mingwen|Han, Jingbo
PMID: 29435055
Journal: Oncotarget. 2017 Dec 20;9(4):4886-4896.
Title: MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway.
Author: Tian, Lei|Zhao, Zhifeng|Xie, Ling|Zhu, JinPeng
PMID: 29435149
Journal: Int J Mol Med. 2018 May;41(5):2755-2763.
Title: LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3beta signaling.
Author: Qiu, Yan-Song|Jiang, Ning-Ning|Zhou, Yan|Yu, Kuai-Yun|Gong, Hong-Yan|Liao, Guang-Jun
PMID: 29436606
Journal: Cancer Sci. 2018 Apr;109(4):1044-1054.
Title: Downregulation of leucine-rich repeats and immunoglobulin-like domains 1 by microRNA-20a modulates gastric cancer multidrug resistance.
Author: Zhou, Lin|Li, Xiaowei|Zhou, Fan|Jin, Zhi'an|Chen, Di|Wang, Pin|Zhang, Shu|Zhuge, Yuzheng|Shang, Yulong|Zou, Xiaoping
PMID: 29450946
Journal: Mol Cancer. 2018 Feb 19;17(1):24.
Title: The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells.
Author: Shao, Genbao|Wang, Ranran|Sun, Aiqin|Wei, Jing|Peng, Ke|Dai, Qian|Yang, Wannian|Lin, Qiong
PMID: 29455656
Journal: PLoS One. 2018 Feb 20;13(2):e0193275.
Title: Galanin is an epigenetically silenced tumor suppressor gene in gastric cancer cells.
Author: Yoon, Daseul|Bae, Kieun|Lee, Min-Kyeong|Kim, Jin Hee|Yoon, Kyong-Ah
PMID: 29462183
Journal: Phytother Res. 2018 Jul;32(7):1289-1296.
Title: Astragaloside IV inhibits TGF-beta1-induced epithelial-mesenchymal transition through inhibition of the PI3K/Akt/NF-kappaB pathway in gastric cancer cells.
Author: Zhu, Jihong|Wen, Ke
PMID: 29480652
Journal: Oncol Rep. 2018 Apr;39(4):1975-1983.
Title: Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway.
Author: Song, Jun|Ma, Sai-Jun|Luo, Jian-Hua|Zhang, Hui|Wang, Ri-Xiong|Liu, Hui|Li, Li|Zhang, Zhi-Guang|Zhou, Rui-Xiang
PMID: 29484412
Journal: Oncol Rep. 2018 Apr;39(4):1843-1852.
Title: Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner.
Author: Wang, Qingling|Yang, Hongli|Zhuo, Qian|Xu, Yanyan|Zhang, Peng
PMID: 29484413
Journal: Biomed Pharmacother. 2018 May;101:355-361.
Title: Sauchinone prevents TGF-beta-induced EMT and metastasis in gastric cancer cells.
Author: He, Zhikuan|Dong, Wenxing|Li, Quanying|Qin, Changjiang|Li, Yongjun
PMID: 29499410
Journal: Int J Mol Med. 2018 Jun;41(6):3157-3166.
Title: Deguelin exerts anticancer activity of human gastric cancer MGC-803 and MKN-45 cells in vitro.
Author: Kang, Wen|Zheng, Xiao|Wang, Ping|Guo, Shanyu
PMID: 29512685
Journal: Int J Mol Med. 2018 Jun;41(6):3167-3174.
Title: REG3A overexpression suppresses gastric cancer cell invasion, proliferation and promotes apoptosis through PI3K/Akt signaling pathway.
Author: Qiu, Yan-Song|Liao, Guang-Jun|Jiang, Ning-Ning
PMID: 29512686
Journal: Cancer Med. 2018 Apr;7(4):1369-1383.
Title: Apoptin-derived peptide reverses cisplatin resistance in gastric cancer through the PI3K-AKT signaling pathway.
Author: Zhou, Danyang|Liu, Wenjing|Liang, Songhe|Sun, Banghao|Liu, Anqi|Cui, Zhongqi|Han, Xue|Yuan, Lijie
PMID: 29522284
Journal: Clin Sci (Lond). 2018 May 23;132(9):1003-1019.
Title: Prader-Willi region non-protein coding RNA 1 suppressed gastric cancer growth as a competing endogenous RNA of miR-425-5p.
Author: Chen, Zihao|Ju, Hongping|Yu, Shan|Zhao, Ting|Jing, Xiaojie|Li, Ping|Jia, Jing|Li, Nan|Tan, Bibo|Li, Yong
PMID: 29535266
Journal: J Exp Clin Cancer Res. 2018 Mar 14;37(1):59.
Title: CDK5RAP3 suppresses Wnt/beta-catenin signaling by inhibiting AKT phosphorylation in gastric cancer.
Author: Zheng, Chao-Hui|Wang, Jia-Bin|Lin, Man-Qiang|Zhang, Peng-Yang|Liu, Li-Chao|Lin, Jian-Xian|Lu, Jun|Chen, Qi-Yue|Cao, Long-Long|Lin, Mi|Tu, Ru-Hong|Xie, Jian-Wei|Li, Ping|Huang, Chang-Ming
PMID: 29540196
Journal: Oncol Lett. 2018 Apr;15(4):4143-4150.
Title: Autophagy flux inhibition augments gastric cancer resistance to the anti-human epidermal growth factor receptor 2 antibody trastuzumab.
Author: Ye, Hua|Chai, Xuyu|Wang, Xiaoyu|Zheng, Qi|Zheng, Dingcheng|Wu, Feng|Zheng, Cheng|Chen, Ping
PMID: 29541179
Journal: Oncol Lett. 2018 Apr;15(4):4683-4689.
Title: Microrna-136 promotes proliferation and invasion ingastric cancer cells through Pten/Akt/P-Akt signaling pathway.
Author: Chen, Xuyan|Huang, Zhiming|Chen, Renpin
PMID: 29541241
Journal: Mol Cancer Ther. 2018 Jun;17(6):1259-1270.
Title: Acquired Resistance to a MET Antibody In Vivo Can Be Overcome by the MET Antibody Mixture Sym015.
Author: Pollmann, Sofie Ellebaek|Calvert, Valerie S|Rao, Shruti|Boca, Simina M|Madhavan, Subha|Horak, Ivan D|Kjaer, Andreas|Petricoin, Emanuel F|Kragh, Michael|Poulsen, Thomas Tuxen
PMID: 29545332
Journal: Invest New Drugs. 2018 Mar 17. pii: 10.1007/s10637-018-0584-y.
Title: The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a']diisoquinoline derivatives in human gastric cancer cells.
Author: Pawlowska, Natalia|Gornowicz, Agnieszka|Bielawska, Anna|Surazynski, Arkadiusz|Szymanowska, Anna|Czarnomysy, Robert|Bielawski, Krzysztof
PMID: 29549610
Journal: J Hematol Oncol. 2018 Mar 20;11(1):43.
Title: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma.
Author: Shi, Cunzhen|Li, Xiangqun|Wang, Xiaogan|Ding, Ning|Ping, Lingyan|Shi, Yunfei|Mi, Lan|Lai, Yumei|Song, Yuqin|Zhu, Jun
PMID: 29554921
Journal: Oncol Lett. 2018 Mar;15(3):3828-3837.
Title: PIAS1 inhibited the metastasis of gastric cancer cell by epithelial-mesenchymal transition regulation within the inflammatory microenvironment.
Author: Wang, Xiaoyu|Wang, Libing|Xu, Yan|Zhang, Guohua|Wu, Yunlin|Chen, Ping
PMID: 29556278
Journal: Oncol Rep. 2018 May;39(5):2450.
Title: [Corrigendum] RLIP76 increases apoptosis through Akt/mTOR signaling pathway in gastric cancer.
Author: Wang, Wenwen|Liu, Juan|Qi, Jianni|Zhang, Junyong|Zhu, Qiang|Qin, Chengyong
PMID: 29565451
Journal: Cell Death Dis. 2018 Apr 1;9(4):434.
Title: Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E.
Author: Zheng, Peiming|Luo, Qin|Wang, Weiwei|Li, Junhua|Wang, Tingting|Wang, Ping|Chen, Lei|Zhang, Peng|Chen, Hui|Liu, Yi|Dong, Ping|Xie, Guohua|Ma, Yanhui|Jiang, Li|Yuan, Xiangliang|Shen, Lisong
PMID: 29567987
Journal: J Int Med Res. 2018 May;46(5):1756-1766.
Title: Inhibitory effects of CP on the growth of human gastric adenocarcinoma BGC-823 tumours in nude mice.
Author: Wang, Hai-Jun|Liu, Yu|Zhou, Bao-Jun|Zhang, Zhan-Xue|Li, Ai-Ying|An, Ran|Yue, Bin|Fan, Li-Qiao|Li, Yong
PMID: 29569987
Journal: PLoS One. 2018 Mar 28;13(3):e0193449.
Title: Osthole inhibits gastric cancer cell proliferation through regulation of PI3K/AKT.
Author: Xu, Xiaojun|Liu, Xiaoyuan|Zhang, Yan
PMID: 29590128
Journal: Med Sci Monit. 2018 Mar 29;24:1847-1855.
Title: Bioinformatic Analysis of GLI1 and Related Signaling Pathways in Chemosensitivity of Gastric Cancer.
Author: Yu, Tao|Jia, Wenzhuo|An, Qi|Cao, Xianglong|Xiao, Gang
PMID: 29596399
Journal: Oncol Rep. 2018 Jun;39(6):2892-2898.
Title: ERBB4 promotes the proliferation of gastric cancer cells via the PI3K/Akt signaling pathway.
Author: Xu, Ji|Gong, Lijie|Qian, Zhenyuan|Song, Guangyuan|Liu, Jinming
PMID: 29620274
Journal: Mol Carcinog. 2018 Aug;57(8):1008-1016.
Title: Dual silencing of EGFR and HER2 enhances the sensitivity of gastric cancer cells to gefitinib.
Author: Wang, Liying|Zhang, Hongfeng|Zheng, Jiaxin|Wei, Xiaoli|Du, Jingwen|Lu, Haibo|Sun, Qiuying|Zhou, Weiyu|Zhang, Rui|Han, Yu
PMID: 29637613
Journal: Oncol Rep. 2018 Jun;39(6):2595-2603.
Title: Cucurbitacin D impedes gastric cancer cell survival via activation of the iNOS/NO and inhibition of the Akt signalling pathway.
Author: Zhang, Yan Zhen|Wang, Chun Feng|Zhang, Lian Feng
PMID: 29658590
Journal: J Cell Biochem. 2018 Aug;119(8):6905-6913.
Title: Long non-coding RNA SNHG14 contributes to gastric cancer development through targeting miR-145/SOX9 axis.
Author: Liu, Zhao|Yan, Yan|Cao, Sizhe|Chen, Yi
PMID: 29667771
Journal: Med Sci Monit. 2018 Apr 18;24:2350-2359.
Title: Exosomes Released by Gastric Cancer Cells Induce Transition of Pericytes Into Cancer-Associated Fibroblasts.
Author: Ning, Xiaofei|Zhang, Hongran|Wang, Cong|Song, Xiuqi
PMID: 29668670
Journal: Cell Physiol Biochem. 2018;46(3):907-924.
Title: CLIC1 Promotes the Progression of Gastric Cancer by Regulating the MAPK/AKT Pathways.
Author: Li, Bo-Pei|Mao, Yuan-Tian|Wang, Zhen|Chen, Ye-Yang|Wang, Ye|Zhai, Chong-Yu|Shi, Bo|Liu, Si-Yu|Liu, Jin-Lu|Chen, Jun-Qiang
PMID: 29669336
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2018 Feb;34(2):129-135.
Title: [beta-Lapachone combined with NVP-BEZ235 inhibit proliferation and migration of BGC-823 gastric cancer cells].
Author: Cui, Xuelian|Chen, Liyan|Sun, Jie|Wang, Yixuan|Lin, Zhenhua
PMID: 29673455
Journal: Eur Rev Med Pharmacol Sci. 2018 Apr;22(7):1929-1936.
Title: miRNA-21 promotes gastric cancer growth by adjusting prostaglandin E2.
Author: Qi, R|Wang, D-T|Xing, L-F|Wu, Z-J
PMID: 29687845
Journal: BMC Cancer. 2018 Apr 24;18(1):462.
Title: CXCL9/10/11, a regulator of PD-L1 expression in gastric cancer.
Author: Zhang, Chenlu|Li, Zhi|Xu, Ling|Che, Xiaofang|Wen, Ti|Fan, Yibo|Li, Ce|Wang, Shuo|Cheng, Yu|Wang, Xiaoxun|Qu, Xiujuan|Liu, Yunpeng
PMID: 29690901
Journal: Oncol Rep. 2018 Jun;39(6):2942-2950.
Title: Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades.
Author: Wang, Xiaona|Zhu, Yanyan|Zhu, Lili|Chen, Xinhuan|Xu, Yanyan|Zhao, Yafei|Shao, Yingzhe|Li, Feng|Jiang, Yanan|Lu, Jing|Huang, Youtian|Chang, Xiaobin|Zhang, Juan|Li, Xiang|Liu, Kangdong|Zhao, Mingyao|Dong, Ziming|Zhao, Jimin
PMID: 29693162
Journal: Oncologist. 2018 Sep;23(9):1092-1102.
Title: Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab.
Author: Diaz-Serrano, Asuncion|Angulo, Barbara|Dominguez, Carolina|Pazo-Cid, Roberto|Salud, Antonieta|Jimenez-Fonseca, Paula|Leon, Ana|Galan, Maria Carmen|Alsina, Maria|Rivera, Fernando|Plaza, J Carlos|Paz-Ares, Luis|Lopez-Rios, Fernando|Gomez-Martin, Carlos
PMID: 29700210
Journal: Iran Biomed J. 2018 Apr 29.
Title: PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer
Author: Iranpour, Mostafa|Nourian, Mahyar|Saffari, Sana|Samizadeh, Esmaeil|Mirghafori, Mahdieh|Iravani, Shahrokh|Ghafouri-Fard, Soudeh
PMID: 29704890
Journal: Per Med. 2018 Mar;15(2):79-86.
Title: Novel AKT1 mutations associated with cell-cycle abnormalities in gastric carcinoma.
Author: Ghatak, Souvik|Lalnunhlimi, Sylvine|Lalrohlui, Freda|Pautu, Jeremy L|Zohmingthanga, John|Kunnumakkara, Ajaikumar B|Kumar, Nachimuthu Senthil
PMID: 29714127
Journal: Microb Pathog. 2018 Aug;121:110-114.
Title: microRNA-107 inhibits gastric cancer cell proliferation and metastasis by targeting PI3K/AKT pathway.
Author: Cheng, Feng|Yang, Zhijun|Huang, Fei|Yin, Liangqiong|Yan, Guosheng|Gong, Guofu
PMID: 29715534
Journal: Theranostics. 2018 Mar 7;8(8):2094-2106.
Title: Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy.
Author: Feng, Junnan|Zhao, Chuanke|Wang, Lixin|Qu, Like|Zhu, Hua|Yang, Zhi|An, Guo|Tian, Huifang|Shou, Chengchao
PMID: 29721065
Journal: Cell Mol Biol (Noisy-le-grand). 2018 Apr 30;64(5):40-45.
Title: CREBRF promotes the proliferation of human gastric cancer cells via the AKT signaling pathway.
Author: Han, Jiming|Zhang, Lu|Zhang, Jing|Jiang, Qiuyu|Tong, Dongdong|Wang, Xiaofei|Gao, Xing|Zhao, Lingyu|Huang, Chen
PMID: 29729692
Journal: Mol Med Rep. 2018 Jul;18(1):147-156.
Title: Salidroside inhibits the proliferation and migration of gastric cancer cells via suppression of Srcassociated signaling pathway activation and heat shock protein 70 expression.
Author: Qi, Zhilin|Tang, Tuo|Sheng, Lili|Ma, Yunfei|Liu, Yinhua|Yan, Liang|Qi, Shimei|Ling, Liefeng|Zhang, Yao
PMID: 29749547
Journal: Dig Dis Sci. 2018 May 16. pii: 10.1007/s10620-018-5111-7.
Title: High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer.
Author: Liu, Yun|Shao, Chen|Zhu, Linqi|Jiang, Sihong|Li, Guanlin|Zhang, Wei|Lin, Yajing|Ni, Ying|Cao, Hui|Shao, Shihe
PMID: 29767389
Journal: J Pharm Pharmacol. 2018 Aug;70(8):1048-1058.
Title: Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells.
Author: Bai, Xin-Yu|Liu, Yuan-Gui|Song, Wu|Li, Ying-Ying|Hou, Dong-Shun|Luo, Hao-Ming|Liu, Ping
PMID: 29770446
Journal: Biochem Biophys Res Commun. 2018 Jul 2;501(4):1068-1073.
Title: MiR-616-3p promotes angiogenesis and EMT in gastric cancer via the PTEN/AKT/mTOR pathway.
Author: Wu, Zhen-Hua|Lin, Chen|Liu, Chen-Chen|Jiang, Wei-Wei|Huang, Ming-Zhu|Liu, Xin|Guo, Wei-Jian
PMID: 29777710
Journal: Gene. 2018 Sep 5;670:130-135.
Title: Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.
Author: Ge, Yuqiu|Liu, Hanting|Qiu, Xiaonan|Ma, Gaoxiang|Wang, Haixiao|Du, Mulong|Wang, Meilin|Zhao, Qinghong|Tao, Guoquan|Chu, Haiyan|Zhang, Zhengdong
PMID: 29802999
Journal: Clin Chem Lab Med. 2018 May 28.
Title: Long non-coding RNA-mediated regulation of signaling pathways in gastric cancer.
Author: Zong, Wei|Ju, Shaoqing|Jing, Rongrong|Cui, Ming
PMID: 29804098
Journal: Oncol Lett. 2018 Jun;15(6):9069-9074.
Title: PRL-3 promotes gastric cancer peritoneal metastasis via the PI3K/AKT signaling pathway in vitro and in vivo.
Author: Zhang, Yang|Li, Zhengrong|Fan, Xiaole|Xiong, Jianbo|Zhang, Guoyang|Luo, Xianshi|Li, Kun|Jie, Zhigang|Cao, Yi|Huang, Zuoxi|Wu, Feng|Xiao, Lin|Duan, Guangling|Chen, Heping
PMID: 29805638
Journal: Onco Targets Ther. 2018 May 17;11:2911-2923.
Title: miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R.
Author: Liu, Na|Yang, Hua|Wang, Hong
PMID: 29844688
Journal: Evid Based Complement Alternat Med. 2018 May 2;2018:7802639.
Title: Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer.
Author: Liu, Xinkui|Wu, Jiarui|Zhang, Dan|Wang, Kaihuan|Duan, Xiaojiao|Meng, Ziqi|Zhang, Xiaomeng
PMID: 29853970
Journal: Cell Death Dis. 2018 May 31;9(6):660.
Title: (S)-crizotinib reduces gastric cancer growth through oxidative DNA damage and triggers pro-survival akt signal.
Author: Ji, Jiansong|Chen, Weiqian|Lian, Weishuai|Chen, Ruijie|Yang, Jinqing|Zhang, Qianqian|Weng, Qiaoyou|Khan, Zia|Hu, Jie|Chen, Xi|Zou, Peng|Chen, Xiaoming|Liang, Guang
PMID: 29855474
Journal: Cancer Gene Ther. 2018 Jun 1. pii: 10.1038/s41417-018-0023-4.
Title: Inhibitor of growth 3 induces cell death by regulating cell proliferation, apoptosis and cell cycle arrest by blocking the PI3K/AKT pathway.
Author: Zhao, Song|Wang, Long|Zhang, Chunmei|Deng, Yu|Zhao, Bai|Ren, Yuxin|Fu, Yingmei|Meng, Xianzhi
PMID: 29855536
Journal: Biomed Pharmacother. 2018 Sep;105:326-333.
Title: Downregulation of circular RNA hsa_circ_0001649 indicates poor prognosis for retinoblastoma and regulates cell proliferation and apoptosis via AKT/mTOR signaling pathway.
Author: Xing, Lichen|Zhang, Leiming|Feng, Yali|Cui, Zhe|Ding, Lin
PMID: 29864621
Journal: Front Pharmacol. 2018 May 15;9:502.
Title: MicroRNA-129-5p Regulates Glycolysis and Cell Proliferation by Targeting the Glucose Transporter SLC2A3 in Gastric Cancer Cells.
Author: Chen, Di|Wang, Hui|Chen, Jie|Li, Zhe|Li, Shengli|Hu, Zhixiang|Huang, Shenglin|Zhao, Yingjun|He, Xianghuo
PMID: 29867504
Journal: Onco Targets Ther. 2018 May 22;11:3025-3033.
Title: LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway.
Author: Ke, Jing|Ma, Peng|Chen, Jinpeng|Qin, Jun|Qian, Haixin
PMID: 29872314
Journal: Cancer Res Treat. 2018 Jun 6. pii: crt.2017.341.
Title: Pan-Pim Kinase Inhibitor AZD1208 Suppresses Tumor Growth and Synergistically Interacts with Akt Inhibition in Gastric Cancer Cells.
Author: Lee, Miso|Lee, Kyung-Hun|Min, Ahrum|Kim, Jeongeun|Kim, Seongyeong|Jang, Hyemin|Lim, Jee Min|Kim, So Hyeon|Ha, Dong-Hyeon|Jeong, Won Jae|Suh, Koung Jin|Yang, Yae-Won|Kim, Tae Yong|Oh, Do-Youn|Bang, Yung-Jue|Im, Seock-Ah
PMID: 29879757
Journal: Biosci Rep. 2018 Jun 13. pii: BSR20180741.
Title: Downregulation of HIF-1alpha inhibits the proliferation, migration and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression.
Author: Zhang, Jingjing|Xu, Jun|Dong, Yonghong|Huang, Bo
PMID: 29899167
Journal: Mol Med Rep. 2018 Aug;18(2):1571-1581.
Title: Overexpression of retinoblastomabinding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3kinase/protein kinase B pathway suppression.
Author: Jin, Xiaoxi|Jiang, Rui|Xiang, Yongsheng|Fan, Zhen|Wu, Zhiwei|Yang, Bo|Yang, Lujun|Wei, Shanshan|Yang, Yan
PMID: 29901205
Journal: Biochem Biophys Res Commun. 2018 Sep 3;503(1):391-396.
Title: Ataxin-3 promotes testicular cancer cell proliferation by inhibiting anti-oncogene PTEN.
Author: Shi, Zhan|Chen, Jiaxin|Zhang, Xiangmin|Chu, Jian|Han, Zhitao|Xu, Da|Gan, Sishun|Pan, Xiuwu|Ye, Jianqing|Cui, Xingang
PMID: 29902454
Journal: Cytogenet Genome Res. 2018;154(4):209-216.
Title: siRNA Targeting of the SNCG Gene Inhibits the Growth of Gastric Carcinoma SGC7901 Cells in vitro and in vivo by Downregulating the Phosphorylation of AKT/ERK.
Author: Fan, Changru|Liu, Jinju|Tian, Jianhai|Zhang, Yuliang|Yan, Maojun|Zhu, Chaoyu
PMID: 29902801
Journal: Oncol Rep. 2018 Aug;40(2):1185-1195.
Title: HGF derived from cancerassociated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.
Author: Ding, Xusheng|Xi, Wenqi|Ji, Jun|Cai, Qu|Jiang, Jinling|Shi, Min|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 29917165
Journal: Oncol Lett. 2018 Jun;15(6):8871-8877.
Title: Chloroform fraction of Serratulae chinensis S. Moore suppresses proliferation and induces apoptosis via the phosphatidylinositide 3-kinase/Akt pathway in human gastric cancer cells.
Author: Cai, Qiaoyan|Lin, Jing|Zhang, Ling|Lin, Shan|Peng, Jun
PMID: 29928328
Journal: Oncol Lett. 2018 Jun;15(6):9777-9785.
Title: MicroRNA-28-5p inhibits the migration and invasion of gastric cancer cells by suppressing AKT phosphorylation.
Author: Xiao, Fangtao|Cheng, Zhenguo|Wang, Pengliang|Gong, Baoheng|Huang, Hanwei|Xing, Yanan|Liu, Funan
PMID: 29928352
Journal: Cell Biol Int. 2018 Sep;42(10):1358-1369.
Title: PKG II inhibits PDGF-BB triggered biological activities by phosphorylating PDGFRbeta in gastric cancer cells.
Author: Wang, Ying|Appiah-Kubi, Kwaku|Lan, Ting|Wu, Min|Pang, Ji|Qian, Hai|Tao, Yan|Jiang, Lu|Wu, Yan|Chen, Yongchang
PMID: 29935031
Journal: Neoplasma. 2018 Sep 19;65(5):693-700.
Title: Anticancer effect of YWHAZ silencing via inducing apoptosis and autophagy in gastric cancer cells.
Author: Guo, F|Jiao, D|Sui, G Q|Sun, L N|Gao, Y J|Fu, Q F|Jin, C X
PMID: 29940752
Journal: Mol Cell Biochem. 2018 Jun 12. pii: 10.1007/s11010-018-3376-y.
Title: Overexpression of ARNT2 is associated with decreased cell proliferation and better prognosis in gastric cancer.
Author: Jia, Yanfei|Hao, Shuhua|Jin, Guangchao|Li, Hongyu|Ma, Xiaoli|Zheng, Yan|Xiao, Dongjie|Wang, Yunshan
PMID: 29948506
Journal: Cell Physiol Biochem. 2018;47(4):1465-1481.
Title: MiR-592 Promotes Gastric Cancer Proliferation, Migration, and Invasion Through the PI3K/AKT and MAPK/ERK Signaling Pathways by Targeting Spry2.
Author: He, Yu|Ge, Yugang|Jiang, Mingkun|Zhou, Jundong|Luo, Dakui|Fan, Hao|Shi, Liang|Lin, Linling|Yang, Li
PMID: 29949784
Journal: Sci Rep. 2018 Jul 4;8(1):10119.
Title: MiR-99b-5p and miR-203a-3p Function as Tumor Suppressors by Targeting IGF-1R in Gastric Cancer.
Author: Wang, Zhenzhen|Zhao, Zhenghao|Yang, Yang|Luo, Mai|Zhang, Min|Wang, Xiaofei|Liu, Liying|Hou, Ni|Guo, Qingqing|Song, Tusheng|Guo, Bo|Huang, Chen
PMID: 29973668
Journal: Cell Death Dis. 2018 Jul 9;9(7):763.
Title: CD45(+)CD33(low)CD11b(dim) myeloid-derived suppressor cells suppress CD8(+) T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer.
Author: Mao, Fang-Yuan|Zhao, Yong-Liang|Lv, Yi-Pin|Teng, Yong-Sheng|Kong, Hui|Liu, Yu-Gang|Wu, Xiao-Long|Hao, Chuan-Jie|Chen, Weisan|Duan, Mu-Bing|Han, Bin|Ma, Qiang|Wang, Ting-Ting|Peng, Liu-Sheng|Zhang, Jin-Yu|Cheng, Ping|Su, Chong-Yu|Fu, Xiao-Long|Zou, Quan-Mi
PMID: 29988030
Journal: Int J Biol Sci. 2018 Jun 3;14(9):1054-1066.
Title: CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer.
Author: Xu, Wenxia|Wei, Qi|Han, Mengjiao|Zhou, Bingluo|Wang, Hanying|Zhang, Jianbing|Wang, Qiang|Sun, Jie|Feng, Lifeng|Wang, Shouyu|Ye, Yang|Wang, Xian|Zhou, Jianwei|Jin, Hongchuan
PMID: 29989092
Journal: Arch Pharm Res. 2018 Jul 10. pii: 10.1007/s12272-018-1049-8.
Title: Autophagy plays a protective role against apoptosis induced by toxicarioside N via the Akt/mTOR pathway in human gastric cancer SGC-7901 cells.
Author: Zhao, Huan-Ge|Zhou, Song-Lin|Lin, Ying-Ying|Wang, Hua|Dai, Hao-Fu|Huang, Feng-Ying
PMID: 29992400
Journal: Cancer Cell Int. 2018 Jul 9;18:97.
Title: Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway.
Author: Chen, Haiqun|Dai, Gang|Cai, Yiting|Gong, Qinhao|Wu, Wei|Gao, Min|Fei, Zhewei
PMID: 30002604
Journal: Oncol Lett. 2018 Aug;16(2):1565-1570.
Title: EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis in vitro through activating ERK1/2 and AKT in a PAR1-dependent manner.
Author: Wang, Qingling|Tang, Yangyang|Wang, Tianyuan|Yang, Hong-Li|Wang, Xinyue|Ma, Hongru|Zhang, Peng
PMID: 30008838
Journal: J Exp Clin Cancer Res. 2018 Jul 16;37(1):152.
Title: miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop.
Author: Zhang, Feifei|Li, Kaitao|Pan, Mingxin|Li, Weidong|Wu, Juan|Li, Mingyi|Zhao, Liang|Wang, Hui
PMID: 30012200
Journal: J Cell Biochem. 2018 Sep 23.
Title: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling.
Author: Wang, Honglei|Zhao, Yongjie|Cao, Lei|Zhang, Judong|Wang, Yu|Xu, Min
PMID: 30013632
Journal: Oncol Rep. 2018 Sep;40(3):1307-1316.
Title: TIPE2 inhibits GC via regulation of cell proliferation, apoptosis and inflammation.
Author: Lin, Zhenhe|Liu, Wenming|Xiao, Chuanxing|Fan, Yanyun|Zhuang, Guohong|Qi, Zhongquan
PMID: 30015980
Journal: Oncol Rep. 2018 Sep;40(3):1565-1573.
Title: NFIB promotes cell growth, aggressiveness, metastasis and EMT of gastric cancer through the Akt/Stat3 signaling pathway.
Author: Wu, Chuanqing|Zhu, Xiaojie|Liu, Weizhen|Ruan, Tuo|Wan, Wenze|Tao, Kaixiong
PMID: 30015981
Journal: Biomed Pharmacother. 2018 Sep;105:1269-1275.
Title: Yes-associated protein enhances proliferation and attenuates sensitivity to cisplatin in human gastric cancer cells.
Author: Lu, Ting|Sun, Liang|Zhu, Xinguo
PMID: 30021363
Journal: Eur Rev Med Pharmacol Sci. 2018 Jul;22(13):4128-4137.
Title: Long non-coding RNA NEAT1 promotes viability and migration of gastric cancer cell lines through up-regulation of microRNA-17.
Author: Wang, C-L|Wang, D|Yan, B-Z|Fu, J-W|Qin, L
PMID: 30024601
Journal: Biochem Biophys Res Commun. 2018 Sep 10;503(3):1491-1497.
Title: miR-5590-3p inhibited tumor growth in gastric cancer by targeting DDX5/AKT/m-TOR pathway.
Author: Wu, Nan|Han, Yuying|Liu, Haiming|Jiang, Mingzuo|Chu, Yi|Cao, Jiayi|Lin, Junchao|Liu, Yuanning|Xu, Bing|Xie, Xin
PMID: 30029874
Journal: Onco Targets Ther. 2018 Jul 19;11:4177-4187.
Title: DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3beta/beta-catenin signaling pathway.
Author: Ge, Hua|Liang, Chaojie|Li, Zhixia|An, Dali|Ren, Shulin|Yue, Chaosen|Wu, Jixiang
PMID: 30050309
Journal: J Dig Dis. 2018 Jul 29.
Title: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer.
Author: Tang, Chao-Tao|Gao, Yun-Jie|Ge, Zhi-Zheng
PMID: 30058122
Journal: Biomol Ther (Seoul). 2018 Jul 30. pii: biomolther.2018.091.
Title: Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with in vitro Anti-Tumor Effects.
Author: Ndolo, Karyn Muzinga|An, Su Jin|Park, Kyeong Ryang|Lee, Hyo Jeong|Yoon, Kyoung Bin|Kim, Yong-Chul|Han, Sun-Young
PMID: 30060294
Journal: Cell Physiol Biochem. 2018;48(4):1457-1467.
Title: Neogenin-1 Promotes Cell Proliferation, Motility, and Adhesion by Up-Regulation of Zinc Finger E-Box Binding Homeobox 1 Via Activating the Rac1/PI3K/AKT Pathway in Gastric Cancer Cells.
Author: Qu, Hengyi|Sun, Huabo|Wang, Xueping
PMID: 30064133
Journal: Gastric Cancer. 2018 Jul 31. pii: 10.1007/s10120-018-0859-1.
Title: E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
Author: Godwin, Tanis D|Kelly, S Thomas|Brew, Tom P|Bougen-Zhukov, Nicola M|Single, Andrew B|Chen, Augustine|Stylianou, Cassie E|Harris, Lawrence D|Currie, Sophie K|Telford, Bryony J|Beetham, Henry G|Evans, Gary B|Black, Michael A|Guilford, Parry J
PMID: 30066183
Journal: Mol Med Rep. 2018 Sep;18(3):3429-3436.
Title: Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Author: Zhang, Xiu-Rong|Wang, Shi-Yao|Sun, Wen|Wei, Chao
PMID: 30066879
Journal: J Biochem Mol Toxicol. 2018 Aug 8:e22202.
Title: Caveolin-1 contributes to anoikis resistance in human gastric cancer SGC-7901 cells via regulating Src-dependent EGFR-ITGB1 signaling.
Author: Wang, Ke|Zhu, Xue|Mei, Dan|Ding, Zhongyang
PMID: 30088837
Journal: Biomed Pharmacother. 2018 Nov;107:185-193.
Title: Down-regulation of lncRNA ADAMTS9-AS2 contributes to gastric cancer development via activation of PI3K/Akt pathway.
Author: Cao, Bole|Liu, Cuixia|Yang, Guifeng
PMID: 30089248
Journal: Nutrients. 2018 Aug 8;10(8). pii: nu10081043.
Title: Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.
Author: Lee, Ho Jeong|Venkatarame Gowda Saralamma, Venu|Kim, Seong Min|Ha, Sang Eun|Raha, Suchismita|Lee, Won Sup|Kim, Eun Hee|Lee, Sang Joon|Heo, Jeong Doo|Kim, Gon Sup
PMID: 30096805
Journal: Int J Mol Sci. 2018 Aug 15;19(8). pii: ijms19082411.
Title: Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers.
Author: Cevenini, Armando|Orru, Stefania|Mancini, Annamaria|Alfieri, Andreina|Buono, Pasqualina|Imperlini, Esther
PMID: 30111747
Journal: Sheng Li Xue Bao. 2018 Aug 25;70(4):397-405.
Title: [Wogonoside reverses cisplatin resistance in SGC7901/cDDP cells through inhibition of PI3K/Akt/Nrf2/ARE signaling pathway].
Author: Wang, Li-Jun|Wang, Shi-Guang|Deng, Tong-Xing
PMID: 30112565
Journal: Exp Ther Med. 2018 Aug;16(2):537-546.
Title: Anti-neuropilin-1 monoclonal antibody suppresses the migration and invasion of human gastric cancer cells via Akt dephosphorylation.
Author: Ding, Yuan|Zhou, Juan|Wang, Shengyu|Li, Yue|Mi, Yanjun|Gao, Shihua|Xu, Yun|Chen, Yuqiang|Yan, Jianghua
PMID: 30116312
Journal: Biomed Pharmacother. 2018 Oct;106:1300-1306.
Title: Xanthohumol induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI3K/Akt/mTOR-kinase in human gastric cancer cells.
Author: Guo, Dongli|Zhang, Baogui|Liu, Shiqi|Jin, Meng
PMID: 30119200
Journal: J Pharmacol Sci. 2018 Jul;137(3):305-312.
Title: Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis.
Author: Zhang, Yunfei|Huang, Ping|Liu, Xuewen|Xiang, Yuchen|Zhang, Te|Wu, Yezi|Xu, Jiaxin|Sun, Zhiting|Zhen, Weiguo|Zhang, Liang|Si, Yuan|Liu, Ying
PMID: 30119963
Journal: Int J Biol Sci. 2018 Jul 27;14(10):1256-1267.
Title: TIMMDC1 Knockdown Inhibits Growth and Metastasis of Gastric Cancer Cells through Metabolic Inhibition and AKT/GSK3beta/beta-Catenin Signaling Pathway.
Author: Liu, Yuan|Huang, Yuyan|Zhang, Jingjing|Pei, Cao|Hu, Jiahui|Lyu, Jianxin|Shen, Yao
PMID: 30123074
Journal: Oncol Lett. 2018 Sep;16(3):3297-3302.
Title: Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3-kinase/protein kinase B/glycogen synthase kinase 3beta signaling pathway.
Author: Lu, Zhen|Xu, Aman|Yuan, Xiao|Chen, Kaiwei|Wang, Likun|Guo, Tao
PMID: 30127928
Journal: J Cell Biochem. 2018 Aug 20.
Title: Knockdown of long noncoding RNA urothelial carcinoma-associated 1 inhibits cell viability, migration, and invasion by regulating microRNA-182 in gastric carcinoma.
Author: Qin, Lei|Jia, Zhihua|Xie, Dawei|Liu, Zhongyuan
PMID: 30129054
Journal: Med Sci Monit. 2018 Aug 22;24:5840-5850.
Title: High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer.
Author: Liu, Shufang|Tian, Ying|Zhu, Chanchan|Yang, Xiaoqing|Sun, Qing
PMID: 30131483
Journal: J Exp Clin Cancer Res. 2018 Aug 22;37(1):198.
Title: PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis.
Author: Xu, Wenting|Yang, Zhen|Xie, Chuan|Zhu, Yin|Shu, Xu|Zhang, Zhe|Li, Nianshuang|Chai, Na|Zhang, Song|Wu, Kaichun|Nie, Yongzhan|Lu, Nonghua
PMID: 30134988
Journal: Cell Physiol Biochem. 2018;49(1):260-270.
Title: Effects of Combination of Anti-CTLA-4 and Anti-PD-1 on Gastric Cancer Cells Proliferation, Apoptosis and Metastasis.
Author: Wang, Bin|Qin, Lei|Ren, Mei|Sun, Hao
PMID: 30138920
Journal: Cell Physiol Biochem. 2018;49(1):322-334.
Title: Long Noncoding RNA EGFR-AS1 Promotes Cell Proliferation by Increasing EGFR mRNA Stability in Gastric Cancer.
Author: Hu, Jiaojiao|Qian, Yingying|Peng, Lipan|Ma, Ling|Qiu, Tianzhu|Liu, Yiqian|Li, Xiao|Chen, Xiaofeng
PMID: 30138934
Journal: Biomed Pharmacother. 2018 Nov;107:841-848.
Title: Knockdown of TMPRSS3 inhibits gastric cancer cell proliferation, invasion and EMT via regulation of the ERK1/2 and PI3K/Akt pathways.
Author: Li, Shun-Le|Chen, Xi|Wu, Tao|Zhang, Xin-Wu|Li, Hua|Zhang, Yan|Ji, Zong-Zheng
PMID: 30142546
Journal: Molecules. 2018 Aug 27;23(9). pii: molecules23092149.
Title: Zeylenone Induces Mitochondrial Apoptosis and Inhibits Migration and Invasion in Gastric Cancer.
Author: Yang, Shuxian|Liao, Yonghong|Li, Liyong|Xu, Xudong|Cao, Li
PMID: 30150551
Journal: BMC Cancer. 2018 Aug 29;18(1):857.
Title: Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells.
Author: Liu, Wenming|Fan, Yanyun|Shi, Ying|Lin, Zhenhe|Huang, Xiaoxiao|Huang, Wei|Shen, Dongyan|Qi, Zhongquan
PMID: 30157801
Journal: J Exp Clin Cancer Res. 2018 Aug 30;37(1):208.
Title: Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through beta-catenin/Erk/Akt signaling in gastric cancer.
Author: Geng, Biao|Pan, Jinshun|Zhao, Ting|Ji, Jie|Zhang, Chen|Che, Ying|Yang, Jing|Shi, Hui|Li, Juan|Zhou, Hong|Mu, Xianmin|Xu, Che|Wang, Chao|Xu, Yue|Liu, Zheng|Wen, Hao|You, Qiang
PMID: 30165890
Journal: Anticancer Drugs. 2018 Aug 30.
Title: Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways.
Author: Lin, Fuxing|Yang, Jie|Muhammad, Umair|Sun, Jing|Huang, Zhenghua|Li, Wei|Lv, Fengxia|Lu, Zhaoxin
PMID: 30169424
Journal: Mol Carcinog. 2018 Sep 3.
Title: TRIM59 overexpression correlates with poor prognosis and contributes to breast cancer progression through AKT signaling pathway.
Author: Liu, Yunxiao|Dong, Yanyan|Zhao, Liping|Su, Lihong|Diao, Kexin|Mi, Xiaoyi
PMID: 30175868
Journal: Exp Mol Pathol. 2018 Aug 31. pii: S0014-4800(18)30307-1.
Title: Geniposide suppresses growth, migration and invasion of MKN45 cells by down-regulation of lncRNA HULC.
Author: Ma, Ji|Ding, Yong
PMID: 30176223
Journal: FEBS Open Bio. 2018 Aug 30;8(9):1508-1523.
Title: MicroRNA-17 as a promising diagnostic biomarker of gastric cancer: An investigation combining TCGA, GEO, meta-analysis, and bioinformatics.
Author: Hu, GaoFeng|Lv, QianWen|Yan, JiaXiu|Chen, LiJun|Du, Juan|Zhao, Ke|Xu, Wei
PMID: 30186751
Journal: Mol Ther Nucleic Acids. 2018 Sep 7;12:578-590.
Title: A Novel Mechanism of Doxorubicin Resistance and Tumorigenesis Mediated by MicroRNA-501-5p-Suppressed BLID.
Author: Xu, Yun-Chao|Liu, Xu|Li, Min|Li, Yan|Li, Chun-Yan|Lu, Ying|Sanches, Jaceline|Wang, Lu|Du, Yue|Mao, Li-Min|Zuo, Si-Bo|Liu, Hui-Ting|Shen, Jie|Wang, Bo|Hou, Li|Li, Lian-Hong|Tang, Jian-Wu|Ju, Jing-Fang|Guan, Hong-Wei|Song, Bo
PMID: 30195794
Journal: Transl Oncol. 2018 Dec;11(6):1379-1389.
Title: Sorcin a Potential Molecular Target for Cancer Therapy.
Author: Shabnam, Bano|Padmavathi, Ganesan|Banik, Kishore|Girisa, Sosmitha|Monisha, Javadi|Sethi, Gautam|Fan, Lu|Wang, Lingzhi|Mao, Xinliang|Kunnumakkara, Ajaikumar B
PMID: 30216763
Journal: Surg Oncol. 2018 Sep;27(3):495-502.
Title: Knockdown of CEACAM19 suppresses human gastric cancer through inhibition of PI3K/Akt and NF-kappaB.
Author: Zhao, Hongying|Xu, Jianjun|Wang, Yu|Jiang, Rongke|Li, Xue|Zhang, Lili|Che, Yingqi
PMID: 30217308
Journal: Drug Dev Res. 2018 Sep 17.
Title: The compound 2-(naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via reactive oxygen species-regulated mitogen-activated protein kinase, protein kinase B, and signal transducer and activator of transcription 3 signaling in human gast
Author: Wang, Jia-Ru|Shen, Gui-Nan|Luo, Ying-Hua|Piao, Xian-Ji|Shen, Meng|Liu, Chang|Wang, Yue|Meng, Ling-Qi|Zhang, Yi|Wang, Hao|Li, Jin-Qian|Xu, Wan-Ting|Liu, Yang|Sun, Hu-Nan|Han, Ying-Hao|Jin, Mei-Hua|Cao, Long-Kui|Jin, Cheng-Hao
PMID: 30222185
Journal: Int J Oncol. 2018 Nov;53(5):2241-2257.
Title: miR-17-92 functions as an oncogene and modulates NF-kappaB signaling by targeting TRAF3 in MGC-803 human gastric cancer cells.
Author: Liu, Fei|Cheng, Li|Xu, Jingjing|Guo, Feng|Chen, Weichang
PMID: 30226589
Journal: Oncol Rep. 2018 Nov;40(5):2997-3005.
Title: Increasing HER2 alpha2,6 sialylation facilitates gastric cancer progression and resistance via the Akt and ERK pathways.
Author: Liu, Naihua|Zhu, Menglu|Linhai, Yingjie|Song, Yuwei|Gui, Xiujuan|Tan, Guoqiang|Li, Jinyuan|Liu, Yan|Deng, Zhendong|Chen, Xiaoting|Wang, Jing|Jia, Lili|He, Xiuzhen|Wang, Xiaoyu|Lin, Shaoqiang
PMID: 30226606
Journal: J Cell Biochem. 2018 Sep 23.
Title: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling.
Author: Wang, Honglei|Zhao, Yongjie|Cao, Lei|Zhang, Judong|Wang, Yu|Xu, Min
PMID: 30246429
Journal: Cell Death Dis. 2018 Sep 24;9(10):998.
Title: Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer.
Author: Chen, Di|Xu, Li|Li, Xiaowei|Chu, Yi|Jiang, Mingzuo|Xu, Bing|Zhao, Min|Wang, Weijie|Wang, Hua|Kang, Huijie|Wang, Kai|Wu, Kaichun|Liang, Jie|Ren, Gui
PMID: 30250066
Journal: Onco Targets Ther. 2018 Sep 11;11:5703-5713.
Title: Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway.
Author: Xu, Wenting|Huang, Ying|Yang, Zhen|Hu, Yi|Shu, Xu|Xie, Chuan|He, Cong|Zhu, Yin|Lu, Nonghua
PMID: 30254463
Journal: Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title: F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author: Yao, Hui|Su, Song|Xia, Dong|Wang, Mingming|Li, Zonglin|Chen, Wangsheng|Ren, Lei|Xu, Liang
PMID: 30257389
Journal: Oncol Rep. 2018 Sep 21.
Title: MicroRNA495 regulates human gastric cancer cell apoptosis and migration through Akt and mTOR signaling.
Author: Wang, Jun|Feng, Weiwei|Dong, Yuanqiang|Mao, Xiang|Guo, Fenghua|Luo, Fen
PMID: 30272336
Journal: Oncol Rep. 2018 Sep 28.
Title: TRIM14 promotes the migration and invasion of gastric cancer by regulating epithelialtomesenchymal transition via activation of AKT signaling regulated by miR1955p.
Author: Wang, Feiqian|Ruan, Litao|Yang, Jinru|Zhao, Qiaoling|Wei, Wei
PMID: 30272351
Journal: Int J Mol Sci. 2018 Sep 30;19(10). pii: ijms19102986.
Title: LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Author: Batool, Samana|Joseph, Thomson Patrick|Hussain, Mushraf|Vuai, Miza S|Khinsar, Kavish H|Din, Syed Riaz Ud|Padhiar, Arshad Ahmed|Zhong, Mintao|Ning, Anhong|Zhang, Wei|Cao, Jing|Huang, Min
PMID: 30274346
Journal: Onco Targets Ther. 2018 Sep 20;11:6111-6118.
Title: Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy.
Author: Li, Liangqing|Zhang, Shengwei|Xie, Diya|Chen, Hui|Zheng, Xuelan|Pan, Dun
PMID: 30275715
Journal: Cancer Med. 2018 Sep 17.
Title: USP14 as a novel prognostic marker promotes cisplatin resistance via Akt/ERK signaling pathways in gastric cancer.
Author: Fu, Ying|Ma, Gang|Liu, Guolong|Li, Bin|Li, Hui|Hao, Xishan|Liu, Liren
PMID: 30296012
Journal: Gene. 2018 Oct 5;682:42-49.
Title: TCF21 inhibits proliferation and chemoresistance through the AKT pathway in human gastric cancer.
Author: Yang, Zhi|Jiang, Xiaodi|Li, Deming|Dong, Qianze|Zhao, Haiying|Jiang, Xiaofeng
PMID: 30296564
Journal: J Cell Biochem. 2018 Oct 9.
Title: Long noncoding RNA HOTAIRM1 inhibits cell progression by regulating miR-17-5p/ PTEN axis in gastric cancer.
Author: Lu, Ruiqi|Zhao, Gang|Yang, Yulong|Jiang, Zhaoyan|Cai, Jingli|Zhang, Zhijue|Hu, Hai
PMID: 30302796
Journal: Cell Death Dis. 2018 Oct 10;9(10):1034.
Title: Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression.
Author: Lv, Yi-Pin|Peng, Liu-Sheng|Wang, Qi-Hong|Chen, Na|Teng, Yong-Sheng|Wang, Ting-Ting|Mao, Fang-Yuan|Zhang, Jin-Yu|Cheng, Ping|Liu, Yu-Gang|Kong, Hui|Wu, Xiao-Long|Hao, Chuan-Jie|Chen, Weisan|Zhu, Jiang|Han, Bin|Ma, Qiang|Li, Ke|Zou, Quanming|Zhuang, Yuan
PMID: 30305610
Journal: Oncogene. 2018 Oct 10. pii: 10.1038/s41388-018-0532-5.
Title: Hsp90ab1 stabilizes LRP5 to promote epithelial-mesenchymal transition via activating of AKT and Wnt/beta-catenin signaling pathways in gastric cancer progression.
Author: Wang, Huanan|Deng, Guangxu|Ai, Meiling|Xu, Zhijun|Mou, Tingyu|Yu, Jiang|Liu, Hao|Wang, Shuang|Li, Guoxin
PMID: 30305727
Journal: Histopathology. 2018 Oct 11.
Title: Clinicopathological significance of RCAN2 production in gastric carcinoma.
Author: Hattori, Yui|Sentani, Kazuhiro|Shinmei, Shunsuke|Oo, Htoo Zarni|Hattori, Takuya|Imai, Takeharu|Sekino, Yohei|Sakamoto, Naoya|Oue, Naohide|Niitsu, Hiroaki|Hinoi, Takao|Ohdan, Hideki|Yasui, Wataru
PMID: 30307052
Journal: Dig Liver Dis. 2018 Aug 24. pii: S1590-8658(18)30899-5.
Title: HOXB9 inhibits proliferation in gastric carcinoma cells via suppression of phosphorylated-Akt and NF-kappaB-dependent Snail expression.
Author: Zhang, Li|Wu, Qinghua|He, Changyu|Liang, Dongyu|Yi, Qingqing|Shi, Junfeng|Wan, Boshun|Yang, Rong|Li, Luyi|Sha, Shuang|Chang, Qing
PMID: 30314948
Journal: Int J Oncol. 2018 Oct 12.
Title: Downregulation of microRNA-4295 enhances cisplatin-induced gastric cancer cell apoptosis through the EGFR/PI3K/Akt signaling pathway by targeting LRIG1.
Author: Yan, Rong|Li, Kang|Yuan, Da-Wei|Wang, Hao-Nan|Zhang, Yong|Dang, Cheng-Xue|Zhu, Kun
PMID: 30320337
Journal: Am J Cancer Res. 2018 Sep 1;8(9):1739-1751. eCollection 2018.
Title: The O-glycosylating enzyme GALNT2 suppresses the malignancy of gastric adenocarcinoma by reducing EGFR activities.
Author: Hu, Wan-Ting|Yeh, Chi-Chuan|Liu, Shin-Yun|Huang, Min-Chuan|Lai, I-Rue
PMID: 30323967
Journal: Oncol Lett. 2018 Nov;16(5):5983-5991.
Title: Hepatocyte growth factor-induced mesenchymal-epithelial transition factor activation leads to insulin-like growth factor 1 receptor inhibitor unresponsiveness in gastric cancer cells.
Author: Liu, Rujiao|Tang, Wenbo|Han, Xiaotian|Geng, Ruixuan|Wang, Chenchen|Zhang, Zhe
PMID: 30333869
Journal: Int Immunopharmacol. 2018 Oct 18;65:312-322.
Title: Methionine enkephalin (MENK) inhibits human gastric cancer through regulating tumor associated macrophages (TAMs) and PI3K/AKT/mTOR signaling pathway inside cancer cells.
Author: Wang, Xiaonan|Jiao, Xue|Meng, Yiming|Chen, Hao|Griffin, Noreen|Gao, Xinghua|Shan, Fengping
PMID: 30343258
Journal: Oncol Lett. 2018 Nov;16(5):5615-5620.
Title: Analysis of correlation between HP infection and activation of PI3K/Akt pathway in mucosal tissues of gastric cancer and precancerous lesions.
Author: Xie, Yi|Liu, Li
PMID: 30344716
Journal: Onco Targets Ther. 2018 Oct 9;11:6693-6703.
Title: Knockdown of RAI14 suppresses the progression of gastric cancer.
Author: Chen, Cheng|Maimaiti, Aihemaiti|Zhang, Xin|Qu, Hui|Sun, Qilong|He, Qingsi|Yu, Wenbin
PMID: 30349303
Journal: Onco Targets Ther. 2018 Oct 10;11:6705-6722.
Title: Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1alpha signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo.
Author: Chen, Min|Lu, Jian|Wei, Wei|Lv, Ying|Zhang, Xiaoqi|Yao, Yuling|Wang, Lei|Ling, Tingsheng|Zou, Xiaoping
PMID: 30349304
Journal: Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806499.
Title: Deregulation of MicroRNA-375 Inhibits Proliferation and Migration in Gastric Cancer in Association With Autophagy-Mediated AKT/mTOR Signaling Pathways.
Author: Yuan, Kai-Tao|Li, Bao-Xia|Yuan, Yu-Jie|Tan, Min|Tan, Jin-Fu|Dai, Wei-Gang|Feng, Wei-Dong|Zuo, Ji-Dong
PMID: 30355273
Journal: Cell Physiol Biochem. 2018 Oct 24;50(4):1332-1345.
Title: FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Author: Huang, Tingting|Liu, Dian|Wang, Yihua|Li, Piao|Sun, Li|Xiong, Huihua|Dai, Yuhong|Zou, Man|Yuan, Xianglin|Qiu, Hong
PMID: 30355943
Journal: Carcinogenesis. 2018 Oct 29. pii: 5146213.
Title: NUCKS1 promotes gastric cancer cell aggressiveness by upregulating IGF-1R and subsequently activating the PI3K/Akt/mTOR signaling pathway.
Author: Huang, Ya-Kai|Kang, Wei-Ming|Ma, Zhi-Qiang|Liu, Yu-Qin|Zhou, Li|Yu, Jian-Chun
PMID: 30371738
Journal: Oncol Lett. 2018 Nov;16(5):5983-5991.
Title: Hepatocyte growth factor-induced mesenchymal-epithelial transition factor activation leads to insulin-like growth factor 1 receptor inhibitor unresponsiveness in gastric cancer cells.
Author: Liu, Rujiao|Tang, Wenbo|Han, Xiaotian|Geng, Ruixuan|Wang, Chenchen|Zhang, Zhe
PMID: 30374835