Literatures

Primary Site >> Esophagus Cancer

Gene >> AKT1

1.
Journal:	J Biol Chem. 2000 Oct 6;275(40):30934-42.
Title:	Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.
Author:	Okano, J\|Gaslightwala, I\|Birnbaum, M J\|Rustgi, A K\|Nakagawa, H
PMID:	10908564

2.
Journal:	Carcinogenesis. 2000 Aug;21(8):1537-46.
Title:	A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity.
Author:	Ramljak, D\|Calvert, R J\|Wiesenfeld, P W\|Diwan, B A\|Catipovic, B\|Marasas, W F\|Victor, T C\|Anderson, L M\|Gelderblom, W C
PMID:	10910956

3.
Journal:	Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):195-201.
Title:	Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways.
Author:	Akimoto, T\|Nonaka, T\|Ishikawa, H\|Sakurai, H\|Saitoh, J I\|Takahashi, T\|Mitsuhashi, N
PMID:	11316564

4.
Journal:	J Thorac Cardiovasc Surg. 2004 Feb;127(2):365-75.
Title:	Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway.
Author:	Nguyen, Dao M\|Chen, G Aaron\|Reddy, Rishindra\|Tsai, Wilson\|Schrump, William D\|Cole, George Jr\|Schrump, David S
PMID:	14762343

5.
Journal:	FEBS Lett. 2005 Aug 1;579(19):4069-75.
Title:	ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma.
Author:	Teraishi, Fuminori\|Kagawa, Shunsuke\|Watanabe, Takanori\|Tango, Yasuhisa\|Kawashima, Takeshi\|Umeoka, Tatsuo\|Nisizaki, Masahiko\|Tanaka, Noriaki\|Fujiwara, Toshiyoshi
PMID:	16023108

6.
Journal:	J Biol Chem. 2005 Sep 16;280(37):32505-11. Epub 2005 Jul 21.
Title:	Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt.
Author:	Chen, Yen-Chung\|Su, Yi-Ning\|Chou, Po-Chien\|Chiang, Wei-Chung\|Chang, Ming-Cheng\|Wang, Liang-Shun\|Teng, Shu-Chun\|Wu, Kou-Juey
PMID:	16036916

7.
Journal:	Acta Med Okayama. 2006 Feb;60(1):25-34.
Title:	Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro.
Author:	Taira, Naruto\|Doihara, Hiroyoshi\|Oota, Tetsuya\|Hara, Fumikata\|Shien, Tadahiko\|Takahashi, Hirotoshi\|Yoshitomi, Seiji\|Ishibe, Youichi\|Shimizu, Nobuyoshi
PMID:	16508686

8.
Journal:	J Clin Oncol. 2006 Apr 1;24(10):1612-9.
Title:	Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.
Author:	Janmaat, Maarten L\|Gallegos-Ruiz, Marielle I\|Rodriguez, Jose A\|Meijer, Gerrit A\|Vervenne, Walter L\|Richel, Dick J\|Van Groeningen, Cees\|Giaccone, Giuseppe
PMID:	16575012

9.
Journal:	Cancer Res. 2006 Nov 1;66(21):10415-24.
Title:	Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras.
Author:	Kim, Seok-Hyun\|Nakagawa, Hiroshi\|Navaraj, Arunasalam\|Naomoto, Yoshio\|Klein-Szanto, Andres J P\|Rustgi, Anil K\|El-Deiry, Wafik S
PMID:	17079462

10.
Journal:	Int J Oncol. 2007 Mar;30(3):605-13.
Title:	Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines.
Author:	Faried, A\|Kurnia, D\|Faried, L S\|Usman, N\|Miyazaki, T\|Kato, H\|Kuwano, H
PMID:	17273761

11.
Journal:	Oncol Rep. 2007 Apr;17(4):887-93.
Title:	The pan-erbB tyrosine kinase inhibitor CI-1033 inhibits human esophageal cancer cells in vitro and in vivo.
Author:	Ako, E\|Yamashita, Y\|Ohira, M\|Yamazaki, M\|Hori, T\|Kubo, N\|Sawada, T\|Hirakawa, K
PMID:	17342332

12.
Journal:	Cancer Biol Ther. 2007 Apr;6(4):534-40.
Title:	IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.
Author:	Takaoka, Munenori\|Kim, Seok-Hyun\|Okawa, Takaomi\|Michaylira, Carmen Z\|Stairs, Douglas B\|Johnstone, Cameron N\|Andl, Claudia D\|Rhoades, Ben\|Lee, James J\|Klein-Szanto, Andres J P\|El-Deiry, Wafik S\|Nakagawa, Hiroshi
PMID:	17457048

13.
Journal:	Br J Cancer. 2007 Jul 16;97(2):218-22. Epub 2007 Jul 10.
Title:	Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer.
Author:	Zhou, Y\|Pan, Y\|Zhang, S\|Shi, X\|Ning, T\|Ke, Y
PMID:	17622239

14.
Journal:	Carcinogenesis. 2007 Nov;28(11):2313-20.
Title:	Id-1 activation of PI3K/Akt/NFkappaB signaling pathway and its significance in promoting survival of esophageal cancer cells.
Author:	Li, Bin\|Cheung, Pak Yan\|Wang, Xianghong\|Tsao, Sai Wah\|Ling, Ming Tat\|Wong, Yong Chuan\|Cheung, Annie L M
PMID:	17638919

15.
Journal:	Genes Dev. 2007 Nov 1;21(21):2788-803.
Title:	The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Author:	Okawa, Takaomi\|Michaylira, Carmen Z\|Kalabis, Jiri\|Stairs, Douglas B\|Nakagawa, Hiroshi\|Andl, Claudia D\|Johnstone, Cameron N\|Klein-Szanto, Andres J\|El-Deiry, Wafik S\|Cukierman, Edna\|Herlyn, Meenhard\|Rustgi, Anil K
PMID:	17974918

16.
Journal:	Am J Gastroenterol. 2008 Apr;103(4):838-41.
Title:	Statins in esophageal cancer cell lines: promising lead?
Author:	Hawk, Ernest T\|Viner, Jaye L
PMID:	18371147

17.
Journal:	Am J Clin Oncol. 2008 Aug;31(4):329-34.
Title:	Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response.
Author:	Javle, Milind\|Pande, Amitkumar\|Iyer, Renuka\|Yang, Gary\|LeVea, Charles\|Wilding, Gregory\|Black, Jennifer\|Nava, Hector\|Nwogu, Chukwumere
PMID:	18845990

18.
Journal:	Oncol Rep. 2008 Dec;20(6):1473-7.
Title:	TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells.
Author:	Wang, Zhi Gang\|Fukazawa, Takuya\|Nishikawa, Toshio\|Watanabe, Nobuyuki\|Sakurama, Kazufumi\|Motoki, Takayuki\|Takaoka, Munenori\|Hatakeyama, Shinji\|Omori, Osamu\|Ohara, Toshiaki\|Tanabe, Shunsuke\|Fujiwara, Yasuhiro\|Shirakawa, Yasuhiro\|Yamatsuji, Tomoki\|Tanaka, No
PMID:	19020730

19.
Journal:	Exp Mol Pathol. 2009 Aug;87(1):42-7.
Title:	Expression of Akt and Mdm2 in human esophageal squamous cell carcinoma.
Author:	Takahashi, Ken\|Miyashita, Masao\|Makino, Hiroshi\|Akagi, Ichiro\|Orita, Hajime\|Hagiwara, Nobutoshi\|Nomura, Tsutomu\|Gabrielson, Edward W\|Tajiri, Takashi
PMID:	19124015

20.
Journal:	J Clin Oncol. 2009 Feb 20;27(6):857-71.
Title:	Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Author:	Hildebrandt, Michelle A T\|Yang, Hushan\|Hung, Mien-Chie\|Izzo, Julie G\|Huang, Maosheng\|Lin, Jie\|Ajani, Jaffer A\|Wu, Xifeng
PMID:	19164214

21.
Journal:	Carcinogenesis. 2009 May;30(5):894-901.
Title:	Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis.
Author:	Yu, Chunping\|Chen, Kun\|Zheng, Haiqing\|Guo, Xianzhi\|Jia, Weihua\|Li, Manzhi\|Zeng, Musheng\|Li, Jun\|Song, Libing
PMID:	19304953

22.
Journal:	Anticancer Res. 2009 Apr;29(4):1163-8.
Title:	Gene expression changes in a chemoresistant model with human esophageal cancer xenografts using cDNA microarray.
Author:	Yoshida, Takahiro\|Miyoshi, Takanori\|Seike, Jun-Ichi\|Yamai, Hiromichi\|Takechi, Hirokazu\|Yuasa, Yasuhiro\|Tangoku, Akira
PMID:	19414360

23.
Journal:	Int J Oncol. 2009 Jul;35(1):187-92.
Title:	Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
Author:	Katoh, Yuriko\|Katoh, Masaru
PMID:	19513567

24.
Journal:	Int J Cancer. 2009 Dec 1;125(11):2576-85.
Title:	Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway.
Author:	Li, Bin\|Tsao, Sai Wah\|Li, Yuk Yin\|Wang, Xianghong\|Ling, Ming Tat\|Wong, Yong Chuan\|He, Qing Yu\|Cheung, Annie L M
PMID:	19551863

25.
Journal:	Curr Mol Med. 2009 Sep;9(7):873-86.
Title:	Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author:	Katoh, Y\|Katoh, M
PMID:	19860666

26.
Journal:	Int J Oncol. 2010 Jan;36(1):19-27.
Title:	A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer.
Author:	Altiok, Soner\|Mezzadra, Heather\|Jagannath, Sanjay\|Tsottles, Nancy\|Rudek, Michelle A\|Abdallah, Nadia\|Berman, David\|Forastiere, Arlene\|Gibson, Michael K
PMID:	19956829

27.
Journal:	Clin Cancer Res. 2010 Jan 1;16(1):226-39.
Title:	Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Author:	Sato, Nagato\|Koinuma, Junkichi\|Fujita, Masahiro\|Hosokawa, Masao\|Ito, Tomoo\|Tsuchiya, Eiju\|Kondo, Satoshi\|Nakamura, Yusuke\|Daigo, Yataro
PMID:	20028748

28.
Journal:	Int J Cancer. 2010 Sep 1;127(5):1197-208.
Title:	Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways.
Author:	Lyros, Orestis\|Mueller, Annett\|Heidel, Florian\|Schimanski, Carl C\|Gockel, Ines\|Galle, Peter R\|Lang, Hauke\|Moehler, Markus
PMID:	20039326

29.
Journal:	Int J Cancer. 2010 Oct 15;127(8):1931-40.
Title:	Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus.
Author:	Kalinina, Tatyana\|Bockhorn, Maximilian\|Kaifi, Jussuf T\|Thieltges, Sabrina\|Gungor, Cenap\|Effenberger, Katharina E\|Strelow, Andrea\|Reichelt, Uta\|Sauter, Guido\|Pantel, Klaus\|Izbicki, Jakob R\|Yekebas, Emre F
PMID:	20104520

30.
Journal:	Mol Med. 2010 Jul-Aug;16(7-8):271-7.
Title:	Upregulation of SPRR3 promotes colorectal tumorigenesis.
Author:	Cho, Dong-Hyung\|Jo, Yoon Kyung\|Roh, Seon Ae\|Na, Young-Soon\|Kim, Tae Won\|Jang, Se Jin\|Kim, Yong Sung\|Kim, Jin Cheon
PMID:	20379613

31.
Journal:	Cancer Invest. 2010 Aug;28(7):679-88.
Title:	Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis.
Author:	Che, Shao-Min\|Zhang, Xiao-Zhi\|Hou, Lei\|Song, Tian-Bao
PMID:	20486853

32.
Journal:	Gene Expr Patterns. 2010 Oct-Dec;10(7-8):361-7.
Title:	Expression patterns of astrocyte elevated gene-1 (AEG-1) during development of the mouse embryo.
Author:	Jeon, Hyun Yong\|Choi, Murim\|Howlett, Eric L\|Vozhilla, Nikollaq\|Yoo, Byoung Kwon\|Lloyd, Joyce A\|Sarkar, Devanand\|Lee, Seok-Geun\|Fisher, Paul B
PMID:	20736086

33.
Journal:	Cell Cycle. 2010 Oct 1;9(19):3892-903. Epub 2010 Oct 20.
Title:	LATS tumor suppressor: a new governor of cellular homeostasis.
Author:	Visser, Stacy\|Yang, Xiaolong
PMID:	20935475

34.
Journal:	Int J Cancer. 2011 Jul 15;129(2):275-84.
Title:	Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer.
Author:	Wei, Lingyun\|Xu, Zhifei
PMID:	20839260

35.
Journal:	Apoptosis. 2011 Feb;16(2):174-83.
Title:	Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability.
Author:	Juan, Hsien-Chia\|Tsai, Hsin-Ting\|Chang, Po-Hao\|Huang, Chi-Ying F\|Hu, Cheng-Po\|Wong, Fen-Hwa
PMID:	21082354

36.
Journal:	Clin Cancer Res. 2011 May 1;17(9):3029-38.
Title:	Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway.
Author:	Hamano, Rie\|Miyata, Hiroshi\|Yamasaki, Makoto\|Kurokawa, Yukinori\|Hara, Johji\|Moon, Jeong Ho\|Nakajima, Kiyokazu\|Takiguchi, Shuji\|Fujiwara, Yoshiyuki\|Mori, Masaki\|Doki, Yuichiro
PMID:	21248297

37.
Journal:	Mol Cancer Res. 2011 Apr;9(4):390-402.
Title:	Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway.
Author:	Liu, Shu-Guang\|Wang, Bo-Shi\|Jiang, Yan-Yi\|Zhang, Tong-Tong\|Shi, Zhi-Zhou\|Yang, Yang\|Yang, Yi-Ling\|Wang, Xiao-Chun\|Lin, De-Chen\|Zhang, Yu\|Yang, Hai\|Cai, Yan\|Zhan, Qi-Min\|Wang, Ming-Rong
PMID:	21310827

38.
Journal:	Cancer Biol Ther. 2011 Jun 1;11(11):950-8. Epub 2011 Jun 1.
Title:	The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells.
Author:	Li, Hongxia\|Gao, Quanli\|Guo, Liping\|Lu, Shih Hsin
PMID:	21467840

39.
Journal:	Dis Esophagus. 2011 Nov;24(8):611-6.
Title:	Phorbol 12,13 dibutyrate behaves in a tumor-inhibitory manner in esophageal adenocarcinoma cell lines.
Author:	Maish, M S\|Carballo, M\|Yetasook, A
PMID:	21595773

40.
Journal:	Anticancer Agents Med Chem. 2011 Sep;11(7):629-37.
Title:	A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma.
Author:	Ucar, Deniz A\|Cox, Audrey\|He, Di-Hua\|Ostrov, David A\|Kurenova, Elena\|Hochwald, Steven N
PMID:	21707510

41.
Journal:	Zhonghua Zhong Liu Za Zhi. 2011 Jun;33(6):410-4.
Title:	[Inhibition of PDK1 gene expression in esophageal cancer EC9706 cells by RNA interference and its effect on their malignant biological behavior].
Author:	Yu, Jing\|Chen, Kui-sheng\|Li, Ya-nan\|Yang, Juan\|Zhao, Lu
PMID:	21875479

42.
Journal:	BMC Cell Biol. 2011 Sep 27;12:41.
Title:	Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells.
Author:	Tonoike, Yurie\|Matsushita, Kazuyuki\|Tomonaga, Takeshi\|Katada, Koji\|Tanaka, Nobuko\|Shimada, Hideaki\|Nakatani, Yukio\|Okamoto, Yoshitaka\|Nomura, Fumio
PMID:	21951621

43.
Journal:	Oncol Rep. 2012 May;27(5):1639-45.
Title:	Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma.
Author:	Guo, Xiao-Fang\|Zhu, Xiao-Fei\|Zhong, Gen-Shen\|Deng, Bao-Guo\|Gao, Zhi-Tao\|Wang, Hui
PMID:	22293713

44.
Journal:	Gastroenterology. 2012 Sep;143(3):675-686.e12.
Title:	Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.
Author:	Ma, Stephanie\|Bao, Jessie Y J\|Kwan, Pak Shing\|Chan, Yuen Piu\|Tong, Carol M\|Fu, Li\|Zhang, Na\|Tong, Amy H Y\|Qin, Yan-Ru\|Tsao, Sai Wah\|Chan, Kwok Wah\|Lok, Si\|Guan, Xin-Yuan
PMID:	22705009

45.
Journal:	Anticancer Res. 2012 Jul;32(7):2827-34.
Title:	Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity.
Author:	Bao, Xiao-Hong\|Takaoka, Munenori\|Hao, Hui-Fang\|Wang, Zhi-Gang\|Fukazawa, Takuya\|Yamatsuji, Tomoki\|Sakurama, Kazufumi\|Sun, Dong-Sheng\|Nagasaka, Takeshi\|Fujiwara, Toshiyoshi\|Naomoto, Yoshio
PMID:	22753744

46.
Journal:	Mol Cancer Res. 2012 Aug;10(8):1032-8.
Title:	Protein kinase casein kinase 2-mediated upregulation of N-cadherin confers anoikis resistance on esophageal carcinoma cells.
Author:	Ko, Hyeonseok\|Kim, Seongrak\|Jin, Cheng-Hao\|Lee, Eunjung\|Ham, Sunyoung\|Yook, Jong In\|Kim, Kunhong
PMID:	22767590

47.
Journal:	World J Gastroenterol. 2012 Aug 21;18(31):4127-35.
Title:	siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin.
Author:	Hasan, Raghibul\|Chauhan, Shyam Singh\|Sharma, Rinu\|Ralhan, Ranju
PMID:	22919244

48.
Journal:	Zhonghua Yi Xue Za Zhi. 2012 Jun 19;92(23):1621-5.
Title:	[Small interfering RNA in silencing cox-2 expression enhances radiosensitivity of esophageal cancer EC9706 cell].
Author:	Wu, Hui\|Lu, Xiao-xu\|Liu, Dong-mei\|Zhao, Guo-qiang\|Fan, Qing-xia
PMID:	22944132

49.
Journal:	Mol Carcinog. 2012 Oct;51(10):796-806.
Title:	Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation.
Author:	Zare, Maryam\|Jazii, Ferdous Rastgar\|Soheili, Zahra-Soheila\|Moghanibashi, Mohamad-Mehdi
PMID:	22965424

50.
Journal:	Cell Cycle. 2012 Nov 1;11(21):3997-4008.
Title:	Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.
Author:	Werneck, Miriam B F\|Hottz, Eugenio\|Bozza, Patricia T\|Viola, Joao P B
PMID:	22992618

51.
Journal:	Asian Pac J Cancer Prev. 2012;13(8):4147-51.
Title:	Silencing of PDK1 gene expression by RNA interference suppresses growth of esophageal cancer.
Author:	Yu, Jing\|Chen, Kui-Sheng\|Li, Ya-Nan\|Yang, Juan\|Zhao, Lu
PMID:	23098536

52.
Journal:	Dis Esophagus. 2013 Jul;26(5):487-95.
Title:	Lapatinib, a dual inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2, potentiates the antitumor effects of cisplatin on esophageal carcinoma.
Author:	Guo, X F\|Zhu, X F\|Zhong, G S\|Deng, B G
PMID:	22458639

53.
Journal:	Dis Esophagus. 2013 Nov-Dec;26(8):823-31.
Title:	Inhibition of microRNA-21 increases radiosensitivity of esophageal cancer cells through phosphatase and tensin homolog deleted on chromosome 10 activation.
Author:	Huang, S\|Li, X-Q\|Chen, Xin\|Che, S-M\|Chen, W\|Zhang, X-Z
PMID:	22958183

54.
Journal:	Cancer Lett. 2013 Jan 28;328(2):198-206.
Title:	Cancer genetics and genomics of human FOX family genes.
Author:	Katoh, Masuko\|Igarashi, Maki\|Fukuda, Hirokazu\|Nakagama, Hitoshi\|Katoh, Masaru
PMID:	23022474

55.
Journal:	Dig Dis Sci. 2013 Mar;58(3):706-14.
Title:	Effect of miR-451 on the biological behavior of the esophageal carcinoma cell line EC9706.
Author:	Wang, Tao\|Zang, Wen-Qiao\|Li, Min\|Wang, Na\|Zheng, Yu-Ling\|Zhao, Guo-Qiang
PMID:	23053883

56.
Journal:	Oncol Rep. 2013 Jan;29(1):45-50.
Title:	Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.
Author:	Bao, Xiao-Hong\|Takaoka, Munenori\|Hao, Hui-Fang\|Fukazawa, Takuya\|Yamatsuji, Tomoki\|Sakurama, Kazufumi\|Takigawa, Nagio\|Nakajima, Motowo\|Fujiwara, Toshiyoshi\|Naomoto, Yoshio
PMID:	23064324

57.
Journal:	Oncol Lett. 2013 Feb;5(2):722-728.
Title:	Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway.
Author:	Zhang, Hong-Bo\|Lu, Ping\|Guo, Qing-Yin\|Zhang, Zhen-Hua\|Meng, Xiang-Yu
PMID:	23420294

58.
Journal:	Clin Cancer Res. 2013 May 1;19(9):2451-9.
Title:	PIK3CA mutation is associated with a favorable prognosis among patients with curatively resected esophageal squamous cell carcinoma.
Author:	Shigaki, Hironobu\|Baba, Yoshifumi\|Watanabe, Masayuki\|Murata, Asuka\|Ishimoto, Takatsugu\|Iwatsuki, Masaaki\|Iwagami, Shiro\|Nosho, Katsuhiko\|Baba, Hideo
PMID:	23532889

59.
Journal:	World J Gastroenterol. 2013 Mar 21;19(11):1736-48.
Title:	Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation.
Author:	Pang, Xue-Li\|He, Gang\|Liu, Yang-Bo\|Wang, Yan\|Zhang, Bo
PMID:	23555162

60.
Journal:	Anticancer Drugs. 2013 Aug;24(7):690-8.
Title:	OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway.
Author:	Liu, Juan\|Qin, Cheng-Kun\|Lv, Wei\|Zhao, Qi\|Qin, Cheng-Yong
PMID:	23652278

61.
Journal:	Cancer Sci. 2013 Aug;104(8):1120-6.
Title:	Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma.
Author:	Shin, Won-Sik\|Kwon, Junhye\|Lee, Hae Won\|Kang, Moon Chul\|Na, Hye-Won\|Lee, Seung-Taek\|Park, Jong Ho
PMID:	23663482

62.
Journal:	PLoS One. 2013 Oct 9;8(10):e75254.
Title:	Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression.
Author:	Hsing, Chung-Hsi\|Kwok, Franky Antonius\|Cheng, Hung-Chi\|Li, Chien-Feng\|Chang, Ming-Shi
PMID:	24130695

63.
Journal:	Acta Pharmacol Sin. 2013 Dec;34(12):1560-7.
Title:	PIK3CA hypomethylation plays a key role in activation of the PI3K/AKT pathway in esophageal cancer in Chinese patients.
Author:	Wang, Wei-feng\|Xie, Yan\|Zhou, Zhi-hua\|Qin, Zheng-hong\|Wu, Jun-chao\|He, Jing-kang
PMID:	24241346

64.
Journal:	J Immunol. 2013 Dec 15;191(12):6261-72.
Title:	The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Author:	Mimura, Kousaku\|Shiraishi, Kensuke\|Mueller, Anja\|Izawa, Shinichiro\|Kua, Ley-Fang\|So, Jimmy\|Yong, Wei-Peng\|Fujii, Hideki\|Seliger, Barbara\|Kiessling, Rolf\|Kono, Koji
PMID:	24244023

65.
Journal:	Anticancer Res. 2013 Dec;33(12):5407-14.
Title:	A novel chemotherapeutic arene ruthenium(II) drug Rawq01 altered the effect of microRNA-21 on PTEN/AKT signaling pathway in esophageal cancer cells.
Author:	Weng, Wenhao\|Wu, Qiong\|Yu, Yongchun\|Mei, Wenjie\|Wang, Xinghe
PMID:	24324076

66.
Journal:	Mol Carcinog. 2014 May;53(5):360-79.
Title:	Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1alpha-induced invasion of human esophageal carcinoma cells.
Author:	Lin, Meng-Liang\|Lu, Yao-Cheng\|Chen, Hung-Yi\|Lee, Chuan-Chun\|Chung, Jing-Gung\|Chen, Shih-Shun
PMID:	23192861

67.
Journal:	Tumour Biol. 2014 Feb;35(2):973-85.
Title:	The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.
Author:	Adachi, Yasushi\|Ohashi, Hirokazu\|Imsumran, Arisa\|Yamamoto, Hiroyuki\|Matsunaga, Yasutaka\|Taniguchi, Hiroaki\|Nosho, Katsuhiko\|Suzuki, Hiromu\|Sasaki, Yasushi\|Arimura, Yoshiaki\|Carbone, David P\|Imai, Kohzoh\|Shinomura, Yasuhisa
PMID:	24026884

68.
Journal:	Oncol Rep. 2014 Jan;31(1):183-8.
Title:	Combination treatment with paclitaxel and doxorubicin inhibits growth of human esophageal squamous cancer cells by inactivation of Akt.
Author:	Lee, Hwan Hee\|Ye, Shuai\|Li, Xiu Juan\|Lee, Kwang Bok\|Park, Man Hee\|Kim, Soo Mi
PMID:	24247637

69.
Journal:	Cancer Res. 2014 Jan 15;74(2):575-85.
Title:	Small molecule agonists of PPAR-gamma exert therapeutic effects in esophageal cancer.
Author:	Sawayama, Hiroshi\|Ishimoto, Takatsugu\|Watanabe, Masayuki\|Yoshida, Naoya\|Sugihara, Hidetaka\|Kurashige, Junji\|Hirashima, Kotaro\|Iwatsuki, Masaaki\|Baba, Yoshifumi\|Oki, Eiji\|Morita, Masaru\|Shiose, Yoshinobu\|Baba, Hideo
PMID:	24272485

70.
Journal:	Oncol Rep. 2014 Feb;31(2):619-24.
Title:	The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Author:	Ui, Takashi\|Morishima, Kazue\|Saito, Shin\|Sakuma, Yuji\|Fujii, Hirofumi\|Hosoya, Yoshinori\|Ishikawa, Shumpei\|Aburatani, Hiroyuki\|Fukayama, Masashi\|Niki, Toshiro\|Yasuda, Yoshikazu
PMID:	24317439

71.
Journal:	J Transl Med. 2014 Jan 4;12:1.
Title:	XB130 promotes proliferation and invasion of gastric cancer cells.
Author:	Shi, Min\|Zheng, Dayong\|Sun, Li\|Wang, Lin\|Lin, Li\|Wu, Yajun\|Zhou, Minyu\|Liao, Wenjun\|Liao, Yulin\|Zuo, Qiang\|Liao, Wangjun
PMID:	24387290

72.
Journal:	Cancer Gene Ther. 2014 Jan;21(1):31-7.
Title:	Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.
Author:	Ma, G\|Kawamura, K\|Shan, Y\|Okamoto, S\|Li, Q\|Namba, M\|Shingyoji, M\|Tada, Y\|Tatsumi, K\|Hiroshima, K\|Shimada, H\|Tagawa, M
PMID:	24434574

73.
Journal:	Chin Med J (Engl). 2014;127(2):353-8.
Title:	Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy.
Author:	Yang, Yang\|Wen, Fengbiao\|Dang, Lifeng\|Fan, Yuxia\|Liu, Donglei\|Wu, Kai\|Zhao, Song
PMID:	24438628

74.
Journal:	Int J Cancer. 2014 Oct 1;135(7):1517-30.
Title:	EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer.
Author:	Fichter, Christiane Daniela\|Timme, Sylvia\|Braun, Julia Alexandra\|Gudernatsch, Verena\|Schopflin, Anja\|Bogatyreva, Lioudmilla\|Geddert, Helene\|Faller, Gerhard\|Klimstra, David\|Tang, Laura\|Hauschke, Dieter\|Werner, Martin\|Lassmann, Silke
PMID:	24510732

75.
Journal:	Clin Cancer Res. 2014 May 15;20(10):2651-62.
Title:	Id1-induced IGF-II and its autocrine/endocrine promotion of esophageal cancer progression and chemoresistance--implications for IGF-II and IGF-IR-targeted therapy.
Author:	Li, Bin\|Tsao, Sai Wah\|Chan, Kwok Wah\|Ludwig, Dale L\|Novosyadlyy, Ruslan\|Li, Yuk Yin\|He, Qing Yu\|Cheung, Annie L M
PMID:	24599933

76.
Journal:	Int J Oncol. 2014 Jun;44(6):2153-9.
Title:	p63 regulates growth of esophageal squamous carcinoma cells via the Akt signaling pathway.
Author:	Ye, Shuai\|Lee, Kwang Bok\|Park, Man Hee\|Lee, Ju-Seog\|Kim, Soo Mi
PMID:	24718831

77.
Journal:	Oncol Rep. 2014 Jun;31(6):2708-12.
Title:	Protein tyrosine kinase 7 plays a tumor suppressor role by inhibiting ERK and AKT phosphorylation in lung cancer.
Author:	Kim, Ji-Hee\|Kwon, Junhye\|Lee, Hae Won\|Kang, Moon Chul\|Yoon, Hyeon-Joon\|Lee, Seung-Taek\|Park, Jong Ho
PMID:	24789704

78.
Journal:	Biomed Res Int. 2014;2014:582730.
Title:	The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells.
Author:	Wang, Jiang-Feng\|Feng, Jian-Guo\|Han, Jing\|Zhang, Bei-Bei\|Mao, Wei-Min
PMID:	24829906

79.
Journal:	Mol Med Rep. 2014 Aug;10(2):848-54.
Title:	Talen-mediated girdin knockout downregulates cell proliferation, migration and invasion in human esophageal carcinoma ECA109 cells.
Author:	Cao, Ke\|Jiang, Wenting\|Cao, Peiguo\|Zou, Qiong\|Xiao, Sheng\|Zhou, Jianda\|Huang, Chenghui
PMID:	24865549

80.
Journal:	Cancer Gene Ther. 2014 Jun;21(6):238-45.
Title:	Akt-mediated transforming growth factor-beta1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cells.
Author:	Xuan, X\|Zeng, Q\|Li, Y\|Gao, Y\|Wang, F\|Zhang, H\|Wang, Z\|He, H\|Li, S
PMID:	24874843

81.
Journal:	Am J Cancer Res. 2014 May 26;4(3):270-8. eCollection 2014.
Title:	Expression of migfilin is increased in esophageal cancer and represses the Akt-beta-catenin activation.
Author:	He, Huan\|Ding, Fang\|Li, Sheng\|Chen, Hongyan\|Liu, Zhihua
PMID:	24959381

82.
Journal:	Biochim Biophys Acta. 2014 Nov;1843(11):2432-7.
Title:	The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells.
Author:	Gronnier, Caroline\|Bruyere, Emilie\|Lahdaoui, Fatima\|Jonckheere, Nicolas\|Perrais, Michael\|Leteurtre, Emmanuelle\|Piessen, Guillaume\|Mariette, Christophe\|Van Seuningen, Isabelle
PMID:	25003315

83.
Journal:	J Mol Med (Berl). 2014 Nov;92(11):1209-23.
Title:	ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways.
Author:	Fichter, Christiane D\|Gudernatsch, Verena\|Przypadlo, Camilla M\|Follo, Marie\|Schmidt, Gudula\|Werner, Martin\|Lassmann, Silke
PMID:	25091467

84.
Journal:	J Pharmacol Sci. 2014;126(1):77-83.
Title:	Resistance to cetuximab in EGFR-overexpressing esophageal squamous cell carcinoma xenografts due to FGFR2 amplification and overexpression.
Author:	Zhang, Yi\|Pan, Tiecheng\|Zhong, Xiaoxuan\|Cheng, Cai
PMID:	25242085

85.
Journal:	Oncotarget. 2014 Nov 30;5(22):11576-87.
Title:	Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway.
Author:	Li, Bin\|Li, Jin\|Xu, Wen Wen\|Guan, Xin Yuan\|Qin, Yan Ru\|Zhang, Li Yi\|Law, Simon\|Tsao, Sai Wah\|Cheung, Annie L M
PMID:	25344912

86.
Journal:	Hepatogastroenterology. 2014 Jul-Aug;61(133):1229-34.
Title:	Licochalcone-A sensitizes human esophageal carcinoma cells to TRAIL-mediated apoptosis by proteasomal degradation of XIAP.
Author:	Yang, Pengfei\|Tuo, Lei\|Wu, Qingquan\|Cao, Xiufeng
PMID:	25436288

87.
Journal:	Hepatogastroenterology. 2014 Jul-Aug;61(133):1229-34.
Title:	Licochalcone-A sensitizes human esophageal carcinoma cells to TRAIL-mediated apoptosis by proteasomal degradation of XIAP.
Author:	Yang, Pengfei\|Tuo, Lei\|Wu, Qingquan\|Cao, Xiufeng
PMID:	25513073

88.
Journal:	Int J Oncol. 2015 Jan;46(1):299-307.
Title:	Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells.
Author:	Liu, Yuting\|Wang, Xiao\|Wang, Ying\|Zhang, Yi\|Zheng, Kai\|Yan, Haizhao\|Zhang, Li\|Chen, Wenbo\|Wang, Xiaoyan\|Liu, Qiuying\|Wang, Shaoxiang\|Wang, Yifei
PMID:	25333998

89.
Journal:	Cell Signal. 2015 Feb;27(2):373-81.
Title:	ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Author:	Kebenko, Maxim\|Drenckhan, Astrid\|Gros, Stephanie J\|Jucker, Manfred\|Grabinski, Nicole\|Ewald, Florian\|Grottke, Astrid\|Schultze, Alexander\|Izbicki, Jakob R\|Bokemeyer, Carsten\|Wellbrock, Jasmin\|Fiedler, Walter
PMID:	25435423

90.
Journal:	J Cancer Res Clin Oncol. 2015 Aug;141(8):1405-16.
Title:	Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
Author:	Wang, Shaoxiang\|Du, Zhan\|Luo, Jie\|Wang, Xiao\|Li, Haiying\|Liu, Yuting\|Zhang, Yong\|Ma, Jiwei\|Xiao, Weiwei\|Wang, Yifei\|Zhong, Xueyun
PMID:	25563492

91.
Journal:	Mol Biol Cell. 2015 Mar 1;26(5):821-31.
Title:	Inactivation of GSK3beta and activation of NF-kappaB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma.
Author:	Paccez, Juliano D\|Duncan, Kristal\|Vava, Akhona\|Correa, Ricardo G\|Libermann, Towia A\|Parker, M Iqbal\|Zerbini, Luiz F
PMID:	25568334

92.
Journal:	BMC Cancer. 2015 Jan 31;15:29.
Title:	MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells.
Author:	Yu, Tingting\|Cao, Risheng\|Li, Shuo\|Fu, Mingen\|Ren, Lihua\|Chen, Weixu\|Zhu, Hong\|Zhan, Qiang\|Shi, Ruihua
PMID:	25637514

93.
Journal:	Tumour Biol. 2015 Aug;36(8):5859-64.
Title:	Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloproteinase 2.
Author:	Zhang, Yi\|Pan, Tiecheng\|Zhong, Xiaoxuan\|Cheng, Cai
PMID:	25724186

94.
Journal:	Drug Des Devel Ther. 2015 Feb 17;9:993-1026.
Title:	Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
Author:	Wang, Yan-Yang\|Yang, Yin-Xue\|Zhao, Ren\|Pan, Shu-Ting\|Zhe, Hong\|He, Zhi-Xu\|Duan, Wei\|Zhang, Xueji\|Yang, Tianxin\|Qiu, Jia-Xuan\|Zhou, Shu-Feng
PMID:	25733817

95.
Journal:	Onco Targets Ther. 2015 Feb 25;8:509-18.
Title:	Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair.
Author:	Liu, Hai\|Yang, Weifang\|Gao, Huaping\|Jiang, Tingting\|Gu, Bengxin\|Dong, Qinghua\|Xu, Wenhong\|Wu, Shixiu\|Sun, Xiaonan
PMID:	25750543

96.
Journal:	PLoS One. 2015 Mar 31;10(3):e0122375.
Title:	MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model.
Author:	Zaidi, Ali H\|Saldin, Lindsey T\|Kelly, Lori A\|Bergal, Linda\|Londono, Ricardo\|Kosovec, Juliann E\|Komatsu, Yoshihiro\|Kasi, Pashtoon M\|Shetty, Amit A\|Keane, Timothy J\|Thakkar, Shyam J\|Huleihel, Luai\|Landreneau, Rodney J\|Badylak, Stephen F\|Jobe, Blair A
PMID:	25826212

97.
Journal:	Cell Cycle. 2015;14(12):1771-8.
Title:	Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells.
Author:	Sullivan, Kelly D\|Nakagawa, Akihisa\|Xue, Ding\|Espinosa, Joaquin M
PMID:	25853217

98.
Journal:	APMIS. 2015 Aug;123(8):639-47.
Title:	Immunohistochemical and molecular analysis of PI3K/AKT/mTOR pathway in esophageal carcinoma.
Author:	Tasioudi, Konstantia E\|Sakellariou, Stratigoula\|Levidou, Georgia\|Theodorou, Dimitrios\|Michalopoulos, Nikolaos V\|Patsouris, Efstratios\|Korkolopoulou, Penelope\|Saetta, Angelica A
PMID:	25912437

99.
Journal:	PLoS One. 2015 May 22;10(5):e0126149.
Title:	Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation.
Author:	He, Enhui\|Pan, Fei\|Li, Guangchao\|Li, Jingjing
PMID:	26000878

100.
Journal:	Oncotarget. 2015 Jul 30;6(21):18674-82.
Title:	High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis.
Author:	Wang, Chun-yu\|Deng, Jia-ying\|Cai, Xu-wei\|Fu, Xiao-long\|Li, Yuan\|Zhou, Xiao-yan\|Wu, Xiang-hua\|Hu, Xi-chun\|Fan, Min\|Xiang, Jia-qing\|Zhang, Ya-wei\|Chen, Hai-quan\|Perez, Rolando\|Jiang, Guo-liang\|Zhao, Kuai-le
PMID:	26124180

101.
Journal:	PLoS One. 2015 Jul 14;10(7):e0133097.
Title:	Correction: Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation.
Author:	He, Enhui\|Pan, Fei\|Li, Guangchao\|Li, Jingjing
PMID:	26173079

102.
Journal:	Int J Clin Exp Pathol. 2015 May 1;8(5):5080-8. eCollection 2015.
Title:	Over-expression of Orai1 mediates cell proliferation and associates with poor prognosis in human non-small cell lung carcinoma.
Author:	Zhan, Zheng-Yu\|Zhong, Lu-Xing\|Feng, Miao\|Wang, Jian-Feng\|Liu, Di-Bin\|Xiong, Jian-Ping
PMID:	26191202

103.
Journal:	Biochem Biophys Res Commun. 2015 Sep 11;465(1):137-44.
Title:	The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121.
Author:	Peng, Yi\|Zhou, Yajuan\|Cheng, Long\|Hu, Desheng\|Zhou, Xiaoyi\|Wang, Zhaohua\|Xie, Conghua\|Zhou, Fuxiang
PMID:	26235881

104.
Journal:	Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Mar;31(2):174-7.
Title:	[Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells].
Author:	Li, Xiu-juan\|Li, Yu-zhen\|Jin, Chun-ting\|Fan, Jie\|Li, Hai-jun
PMID:	26248429

105.
Journal:	Gastroenterology. 2015 Dec;149(7):1825-1836.e5.
Title:	Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells.
Author:	Yu, Valen Zhuoyou\|Wong, Victor Chun-Lam\|Dai, Wei\|Ko, Josephine Mun-Yee\|Lam, Alfred King-Yin\|Chan, Kwok Wah\|Samant, Rajeev S\|Lung, Hong Lok\|Shuen, Wai Ho\|Law, Simon\|Chan, Yuen Piu\|Lee, Nikki Pui-Yue\|Tong, Daniel King Hung\|Law, Tsz Ting\|Lee, Victor Ho-Fun\|L
PMID:	26302489

106.
Journal:	Oncotarget. 2015 Sep 22;6(28):25897-916.
Title:	IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma.
Author:	Myers, Amy L\|Lin, Lin\|Nancarrow, Derek J\|Wang, Zhuwen\|Ferrer-Torres, Daysha\|Thomas, Dafydd G\|Orringer, Mark B\|Lin, Jules\|Reddy, Rishindra M\|Beer, David G\|Chang, Andrew C
PMID:	26317790

107.
Journal:	Oncotarget. 2015 Oct 20;6(32):33438-55.
Title:	Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation.
Author:	Kresty, Laura A\|Weh, Katherine M\|Zeyzus-Johns, Bree\|Perez, Laura N\|Howell, Amy B
PMID:	26378019

108.
Journal:	Evid Based Complement Alternat Med. 2015;2015:464937.
Title:	Antitumor Activity of Tenacissoside H on Esophageal Cancer through Arresting Cell Cycle and Regulating PI3K/Akt-NF-kappaB Transduction Cascade.
Author:	Jia, Yong-Sen\|Hu, Xue-Qin\|Gabriella, Hegyi\|Qin, Li-Juan\|Meggyeshazi, Nora
PMID:	26495015

109.
Journal:	Int J Oncol. 2015 Dec;47(6):2255-63.
Title:	Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells.
Author:	Hadisaputri, Yuni Elsa\|Miyazaki, Tatsuya\|Suzuki, Shigemasa\|Kubo, Norio\|Zuhrotun, Ade\|Yokobori, Takehiko\|Abdulah, Rizky\|Yazawa, Shin\|Kuwano, Hiroyuki
PMID:	26498695

110.
Journal:	Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Sep;31(5):465-8.
Title:	[The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells].
Author:	Li, Xiu-juan\|Luo, Qiang\|Sun, Li\|Lit, Hua\|Jin, Chun-ting\|Fan, Jie\|Li, Yu-zhen
PMID:	26827544

111.
Journal:	Oncogene. 2016 Mar 24;35(12):1585-95.
Title:	Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming.
Author:	Srinivasan, S\|Guha, M\|Dong, D W\|Whelan, K A\|Ruthel, G\|Uchikado, Y\|Natsugoe, S\|Nakagawa, H\|Avadhani, N G
PMID:	26148236

112.
Journal:	Tumour Biol. 2016 Feb;37(2):1853-62.
Title:	Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway.
Author:	Yang, Yan\|Sun, Xiangdong\|Yang, Yuehua\|Yang, Xi\|Zhu, Hongcheng\|Dai, Shengbin\|Chen, Xiaochen\|Zhang, Hao\|Guo, Qing\|Song, Yaqi\|Wang, Feng\|Cheng, Hongyan\|Sun, Xinchen
PMID:	26318432

113.
Journal:	Tumour Biol. 2016 Apr;37(4):4679-88.
Title:	Endostatin combined with radiotherapy suppresses vasculogenic mimicry formation through inhibition of epithelial-mesenchymal transition in esophageal cancer.
Author:	Chen, Xiaochen\|Zhang, Hao\|Zhu, Hongcheng\|Yang, Xi\|Yang, Yuehua\|Yang, Yan\|Min, Hua\|Chen, Guangzong\|Liu, Jia\|Lu, Jing\|Cheng, Hongyan\|Sun, Xinchen
PMID:	26511968

114.
Journal:	Tumour Biol. 2016 May;37(5):6371-8.
Title:	Regulation of CXCR4/AKT-signaling-induced cell invasion and tumor metastasis by RhoA, Rac-1, and Cdc42 in human esophageal cancer.
Author:	Guo, Jing\|Yu, Xiaofang\|Gu, Jie\|Lin, Zongwu\|Zhao, Guangyin\|Xu, Fengkai\|Lu, Chunlai\|Ge, Di
PMID:	26631033

115.
Journal:	Mol Med Rep. 2016 Feb;13(2):1097-104.
Title:	Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling.
Author:	Tantai, Ji-Cheng\|Zhang, Yao\|Zhao, Heng
PMID:	26647768

116.
Journal:	Cell Biol Int. 2016 May;40(5):524-33.
Title:	FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro.
Author:	Shi, Hui\|Xu, Jingjing\|Zhao, Rui\|Wu, Huiqun\|Gu, Luo\|Chen, Yijiang
PMID:	26833879

117.
Journal:	Asian Pac J Trop Med. 2016 Jan;9(1):86-90.
Title:	Effect of recombinant human endostatin onradiotherapy for esophagus cancer.
Author:	Liu, Gao-Feng\|Chang, Hui\|Li, Bao-Tian\|Zhang, Yong\|Li, Dan-Dan\|Liu, Yan\|Yang, Yang
PMID:	26851794

118.
Journal:	Int J Cancer. 2016 Jun 15;138(12):2940-51.
Title:	DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Author:	Ng, Hoi Yan\|Ko, Josephine Mun-Yee\|Yu, Valen Zhuoyou\|Ip, Joseph Chok Yan\|Dai, Wei\|Cal, Santiago\|Lung, Maria Li
PMID:	26856390

119.
Journal:	Oncol Rep. 2016 Jul;36(1):223-30.
Title:	Knockdown of DDX46 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma cells.
Author:	Li, Bin\|Li, Yu-Min\|He, Wen-Ting\|Chen, Hao\|Zhu, Hong-Wen\|Liu, Tao\|Zhang, Jian-Hua\|Song, Tie-Niu\|Zhou, Ya-Li
PMID:	27176873

120.
Journal:	Tumour Biol. 2016 Sep;37(9):12061-12070. Epub 2016 May 17.
Title:	MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer.
Author:	Wu, Yan-Ran\|Qi, Hai-Jun\|Deng, Dan-Fang\|Luo, Ying-Ying\|Yang, Sheng-Lan
PMID:	27188433

121.
Journal:	World J Gastroenterol. 2016 May 28;22(20):4868-80.
Title:	Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
Author:	Zeng, Ling\|Zhou, Hai-Yun\|Tang, Na-Na\|Zhang, Wei-Feng\|He, Gui-Jun\|Hao, Bo\|Feng, Ya-Dong\|Zhu, Hong
PMID:	27239113

122.
Journal:	Cancer Lett. 2016 Sep 28;380(1):47-58.
Title:	NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells.
Author:	Takase, Nobuhisa\|Koma, Yu-Ichiro\|Urakawa, Naoki\|Nishio, Mari\|Arai, Noriaki\|Akiyama, Hiroaki\|Shigeoka, Manabu\|Kakeji, Yoshihiro\|Yokozaki, Hiroshi
PMID:	27317650

123.
Journal:	Mol Med Rep. 2016 Aug;14(2):1531-7.
Title:	Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells.
Author:	Yang, Peng\|Zhao, Jiaying\|Hou, Liying\|Yang, Lei\|Wu, Kun\|Zhang, Linyou
PMID:	27357907

124.
Journal:	Oncogenesis. 2016 Jul 4;5(7):e239.
Title:	Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling.
Author:	Kuo, K-T\|Chen, C-L\|Chou, T-Y\|Yeh, C-T\|Lee, W-H\|Wang, L-S
PMID:	27376780

125.
Journal:	Oncol Lett. 2016 Aug;12(2):971-976. Epub 2016 Jun 15.
Title:	Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-kappaB and PI3K/Akt signaling pathways.
Author:	Jin, Zhiliang\|Yan, Wei\|Jin, Hui\|Ge, Changzheng\|Xu, Yanhua
PMID:	27446379

126.
Journal:	Med Sci Monit. 2016 Jul 25;22:2624-34.
Title:	Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo.
Author:	Li, Hongxia\|Juan, Li\|Xia, Leiming\|Wang, Yi\|Bao, Yangyi\|Sun, Guoping
PMID:	27453171

127.
Journal:	Toxicol Lett. 2016 Nov 2;261:49-58.
Title:	beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro.
Author:	Zhang, Yanting\|Zhu, Xiangzhan\|Huang, Tuanjie\|Chen, Lei\|Liu, Yanxia\|Li, Qinghua\|Song, Jishi\|Ma, Shanshan\|Zhang, Kun\|Yang, Bo\|Guan, Fangxia
PMID:	27586268

128.
Journal:	Oncol Lett. 2016 Sep;12(3):2232-2238.
Title:	Aloe-emodin suppresses esophageal cancer cell TE1 proliferation by inhibiting AKT and ERK phosphorylation.
Author:	Chang, Xiaobin\|Zhao, Jimin\|Tian, Fang\|Jiang, Yanan\|Lu, Jing\|Ma, Junfen\|Zhang, Xiaoyan\|Jin, Guoguo\|Huang, Youtian\|Dong, Zigang\|Liu, Kangdong\|Dong, Ziming
PMID:	27602169

129.
Journal:	Mol Cell Biochem. 2016 Nov;422(1-2):161-170. Epub 2016 Sep 19.
Title:	Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN.
Author:	Jin, Ying-Ying\|Chen, Qing-Juan\|Xu, Kun\|Ren, Hong-Tao\|Bao, Xing\|Ma, Yi-Nan\|Wei, Yang\|Ma, Hong Bing
PMID:	27644195

130.
Journal:	PLoS One. 2016 Nov 22;11(11):e0166453.
Title:	The Synthetic beta-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
Author:	Chiu, Wen-Chin\|Lee, Yi-Chen\|Su, Yu-Han\|Wang, Yen-Yun\|Tsai, Chun-Hao\|Hou, Yi-An\|Wang, Chie-Hong\|Huang, Ying-Fong\|Huang, Chih-Jen\|Chou, Shah-Hwa\|Hsieh, Pei-Wen\|Yuan, Shyng-Shiou F
PMID:	27875549

131.
Journal:	Cancer Res Treat. 2017 Jul;49(3):778-789.
Title:	Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo.
Author:	Tang, Jian-Cai\|An, Rui\|Jiang, Yi-Qing\|Yang, Jian
PMID:	27857021

132.
Journal:	Oncotarget. 2017 Jan 24;8(4):6681-6690.
Title:	Integrin alpha6 promotes esophageal cancer metastasis and is targeted by miR-92b.
Author:	Ma, Gang\|Jing, Chao\|Huang, Furong\|Li, Xukun\|Cao, Xiufeng\|Liu, Zhihua
PMID:	28036265

133.
Journal:	Oncol Res. 2017 Aug 7;25(7):1061-1068.
Title:	Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells.
Author:	Fan, Huijie\|Li, Jing\|Jia, Yongxu\|Wu, Jingjing\|Yuan, Long\|Li, Mingjun\|Wei, Jiangqi\|Xu, Benling
PMID:	28109079

134.
Journal:	Med Oncol. 2017 Mar;34(3):32.
Title:	RICTOR expression in esophageal squamous cell carcinoma and its clinical significance.
Author:	Jiang, Wei-Jia\|Feng, Ru-Xue\|Liu, Jia-Tao\|Fan, Lu-Lu\|Wang, Hua\|Sun, Guo-Ping
PMID:	28132115

135.
Journal:	Gastroenterology. 2017 Jun;152(8):1985-1997.e12.
Title:	Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis.
Author:	Cheng, Xinxin\|Wei, Lixuan\|Huang, Xudong\|Zheng, Jian\|Shao, Mingming\|Feng, Ting\|Li, Jun\|Han, Yaling\|Tan, Wenle\|Tan, Wen\|Lin, Dongxin\|Wu, Chen
PMID:	28209530

136.
Journal:	Med Sci Monit. 2017 May 2;23:2096-2103.
Title:	Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway.
Author:	Shen, Zhipeng\|Xu, Lixia\|Li, Juan\|Zhang, Ni
PMID:	28463955

137.
Journal:	World J Gastroenterol. 2017 Apr 14;23(14):2511-2518.
Title:	Berberine displays antitumor activity in esophageal cancer cells in vitro.
Author:	Jiang, Shu-Xian\|Qi, Bo\|Yao, Wen-Jian\|Gu, Cheng-Wei\|Wei, Xiu-Feng\|Zhao, Yi\|Liu, Yu-Zhen\|Zhao, Bao-Sheng
PMID:	28465635

138.
Journal:	Oncol Rep. 2017 Jun;37(6):3329-3340.
Title:	A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer.
Author:	Cao, Hai-Ying\|Guo, Xiao-Fang\|Zhu, Xiao-Fei\|Li, Sai-Sai\|Zhen, Yong-Su
PMID:	28498434

139.
Journal:	Oncol Rep. 2017 Jun;37(6):3590-3596.
Title:	MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway.
Author:	Qiu, Yun-Tan\|Wang, Wen-Jun\|Zhang, Bing\|Mei, Li-Li\|Shi, Zhi-Zhou
PMID:	28498460

140.
Journal:	Tumour Biol. 2017 Jun;39(6):1010428317705748.
Title:	Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway.
Author:	Zhou, Fang\|Li, Yan-Hua\|Wang, Jian-Jun\|Pan, Jia\|Lu, Hong
PMID:	28631572

141.
Journal:	Environ Toxicol Pharmacol. 2017 Sep;54:7-13.
Title:	Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways.
Author:	Gu, Zhen-Fang\|Zhang, Zi-Teng\|Wang, Jun-Ye\|Xu, Bao-Bin
PMID:	28667862

142.
Journal:	Biochem Biophys Res Commun. 2017 Sep 23;491(3):622-628.
Title:	RACK1 promotes radiation resistance in esophageal cancer via regulating AKT pathway and Bcl-2 expression.
Author:	Liu, Bowen\|Wang, Cong\|Chen, Pengxiang\|Wang, Lu\|Cheng, Yufeng
PMID:	28760343

143.
Journal:	Photodiagnosis Photodyn Ther. 2017 Aug 12. pii: S1572-1000(17)30265-X.
Title:	Influence and mechanism of 5-aminolevulinic acid-photodynamic therapy on the metastasis of esophageal carcinoma.
Author:	Zhang, Xiaona\|Cai, Longmei\|He, Jingcai\|Li, Xiaoyan\|Li, Libo\|Chen, Xiaohua\|Lan, Ping
PMID:	28811223

144.
Journal:	J Cell Biochem. 2017 Aug 31.
Title:	FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma.
Author:	Shi, Yuanyuan\|Liu, Xuejiao\|Fredimoses, Mangaladoss\|Song, Mengqiu\|Chen, Hanyong\|Liu, Kangdong\|Lee, Mee-Hyun\|Dong, Zigang
PMID:	28857247

145.
Journal:	Oncol Res. 2017 Sep 6.
Title:	Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1.
Author:	Ma, Junxun\|Wan, Lijie\|Li, Jinyu\|Zhang, Guoqing\|Tao, Haitao\|Li, Xiaoyan\|Sun, Danyang\|Hu, Yi
PMID:	28899457

146.
Journal:	Drug Deliv. 2017 Nov;24(1):1549-1564.
Title:	GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways.
Author:	Pi, Jiang\|Jiang, Jinhuan\|Cai, Huaihong\|Yang, Fen\|Jin, Hua\|Yang, Peihui\|Cai, Jiye\|Chen, Zheng W
PMID:	29019267

147.
Journal:	Oncol Lett. 2017 Oct;14(4):4897-4905.
Title:	Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway.
Author:	Qian, Li-Qiang\|Li, Xia-Qin\|Ye, Peng-Hui\|Su, Hao-Yuan\|Wang, Gang\|Liu, Yan\|Shen, Gen-Hai\|Gao, Quan-Gen
PMID:	29085498

148.
Journal:	Cancer Cell Int. 2017 Oct 30;17:98.
Title:	Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway.
Author:	Li, Sheng\|Shen, Xiu-Yin\|Ouyang, Ting\|Qu, Yuhua\|Luo, Tao\|Wang, Hua-Qiao
PMID:	29093644

149.
Journal:	Oncol Lett. 2017 Dec;14(6):6604-6610.
Title:	Autophagy inhibition contributes to Endostar sensitization in esophageal squamous cell carcinoma.
Author:	Han, Xinghua\|Wang, Zhanggui\|Hu, Bin\|Xu, Jianming
PMID:	29163691

150.
Journal:	Front Oncol. 2017 Nov 1;7:258.
Title:	Delineation of the HPV11E6 and HPV18E6 Pathways in Initiating Cellular Transformation.
Author:	Mwapagha, Lamech M\|Tiffin, Nicki\|Parker, M Iqbal
PMID:	29164058

151.
Journal:	Oncotarget. 2017 Oct 30;8(62):105222-105237.
Title:	Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling.
Author:	Yue, Ying\|Song, Mengjia\|Qiao, Yamin\|Li, Pupu\|Yuan, Yiqiang\|Lian, Jingyao\|Wang, Suying\|Zhang, Yi
PMID:	29285246

152.
Journal:	Oncogene. 2018 Feb 15;37(7):935-943.
Title:	Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation.
Author:	Shi, F\|Shang, L\|Yang, L-Y\|Jiang, Y-Y\|Wang, X-M\|Hao, J-J\|Zhang, Y\|Huang, D-K\|Cai, Y\|Xu, X\|Zhan, Q-M\|Jia, X-M\|Cao, Y\|Wang, M-R
PMID:	29059172

153.
Journal:	Mol Med Rep. 2018 Jan;17(1):549-555.
Title:	UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway.
Author:	He, Dan\|Zhang, Suolin
PMID:	29115622

154.
Journal:	Exp Cell Res. 2018 Jan 15;362(2):362-369.
Title:	Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway.
Author:	Jin, Yingying\|Xu, Kun\|Chen, Qingjuan\|Wang, Baofeng\|Pan, Jiyuan\|Huang, Shan\|Wei, Yang\|Ma, Hongbing
PMID:	29208461

155.
Journal:	Ann Thorac Surg. 2018 Feb;105(2):363-370.
Title:	HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells.
Author:	Goltsov, Alexei A\|Fang, Bingliang\|Pandita, Tej K\|Maru, Dipen M\|Swisher, Stephen G\|Hofstetter, Wayne L
PMID:	29223420

156.
Journal:	J Cancer. 2018 Jan 1;9(1):32-40.
Title:	Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo.
Author:	Tang, Jian-Cai\|Zhao, Jia\|Long, Feng\|Chen, Jian-Ye\|Mu, Bo\|Jiang, Zhen\|Ren, Yonggan\|Yang, Jian
PMID:	29290767

157.
Journal:	Mol Med Rep. 2018 Mar;17(3):4599-4604.
Title:	Vitexin induces G2/Mphase arrest and apoptosis via Akt/mTOR signaling pathway in human glioblastoma cells.
Author:	Zhang, Guangning\|Li, Dongyuan\|Chen, Hao\|Zhang, Junchen\|Jin, Xingyi
PMID:	29328424

158.
Journal:	Cell Death Dis. 2018 Jan 16;9(2):17.
Title:	Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling.
Author:	Cao, Ying-Ya\|Yu, Jing\|Liu, Ting-Ting\|Yang, Kai-Xia\|Yang, Li-Yan\|Chen, Qun\|Shi, Feng\|Hao, Jia-Jie\|Cai, Yan\|Wang, Ming-Rong\|Lu, Wei-Hua\|Zhang, Yu
PMID:	29339720

159.
Journal:	Onco Targets Ther. 2018 Jan 4;11:211-220.
Title:	RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression.
Author:	Liu, Bowen\|Wang, Cong\|Chen, Pengxiang\|Cheng, Bo\|Cheng, Yufeng
PMID:	29379302

160.
Journal:	Oncotarget. 2017 Dec 1;9(1):853-865.
Title:	Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma.
Author:	Wang, Lei\|Jin, Joy Q\|Zhou, Yong\|Tian, Ziqiang\|Jablons, David M\|He, Biao
PMID:	29416661

161.
Journal:	Oncol Lett. 2018 Mar;15(3):2939-2945.
Title:	Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway.
Author:	He, Yindi\|Tan, Xiaojun\|Hu, Hui\|Wang, Qinjia\|Hu, Xi\|Cai, Xianbin\|Guan, Yinghong\|Chen, Binming\|Jing, Xubin
PMID:	29435022

162.
Journal:	Hum Pathol. 2018 May;75:116-124.
Title:	Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers.
Author:	Li, Guanhua\|Dong, Taotao\|Yang, Dong\|Gao, Aiqin\|Luo, Judong\|Yang, Hongyan\|Wang, Linlin
PMID:	29452214

163.
Journal:	Gastroenterology. 2018 Jun;154(8):2137-2151.e1.
Title:	Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.
Author:	Xie, Jian-Jun\|Jiang, Yan-Yi\|Jiang, Yuan\|Li, Chun-Quan\|Lim, Mei-Chee\|An, Omer\|Mayakonda, Anand\|Ding, Ling-Wen\|Long, Lin\|Sun, Chun\|Lin, Le-Hang\|Chen, Li\|Wu, Jian-Yi\|Wu, Zhi-Yong\|Cao, Qi\|Fang, Wang-Kai\|Yang, Wei\|Soukiasian, Harmik\|Meltzer, Stephen J\|Yang, He
PMID:	29454790

164.
Journal:	Oncol Lett. 2018 Mar;15(3):3937-3943.
Title:	miR302a inhibits the proliferation of esophageal cancer cells through the MAPK and PI3K/Akt signaling pathways.
Author:	Xia, Daokui\|Tian, Shumei\|Chen, Zhen\|Qin, Wenchao\|Liu, Quan
PMID:	29456742

165.
Journal:	Technol Cancer Res Treat. 2018 Jan 1;17:1533033818758772.
Title:	The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma.
Author:	Wu, Ning\|Du, Zunguo\|Zhu, Yongjun\|Song, Yang\|Pang, Liewen\|Chen, Zhiming
PMID:	29463194

166.
Journal:	Oncotarget. 2018 Jan 10;9(10):9425-9441.
Title:	Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NF-kB/COX-2/VEGF axis.
Author:	Huang, Chien-Yu\|Lee, Chia-Hwa\|Tu, Chao-Chiang\|Wu, Chih-Hsiung\|Huang, Ming-Te\|Wei, Po-Li\|Chang, Yu-Jia
PMID:	29507700

167.
Journal:	Cell Death Differ. 2018 Mar 6. pii: 10.1038/s41418-018-0084-9.
Title:	LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.
Author:	Liang, Yan\|Chen, Xuedan\|Wu, Yuanyuan\|Li, Juan\|Zhang, Shixin\|Wang, Kai\|Guan, Xingying\|Yang, Kang\|Bai, Yun
PMID:	29511340

168.
Journal:	Int J Biochem Cell Biol. 2018 Jun;99:43-51.
Title:	NDRG2 suppresses proliferation, migration, invasion and epithelial-mesenchymal transition of esophageal cancer cells through regulating the AKT/XIAP signaling pathway.
Author:	Yang, Cheng-Liang\|Zheng, Xiao-Li\|Ye, Ke\|Ge, Hong\|Sun, Ya-Nan\|Lu, Yu-Fei\|Fan, Qing-Xia
PMID:	29530788

169.
Journal:	Oncotarget. 2018 Jan 30;9(16):12769-12780.
Title:	The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma.
Author:	Baumann, Alexander\|Buchberger, Anna Maria S\|Piontek, Guido\|Schuttler, Dominik\|Rudelius, Martina\|Reiter, Rudolf\|Gebel, Lena\|Piendl, Gerhard\|Brockhoff, Gero\|Pickhard, Anja
PMID:	29560108

170.
Journal:	Oncogene. 2018 Jun;37(26):3471-3484.
Title:	Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.
Author:	Shinno, Naoki\|Kimura, Hirokazu\|Sada, Ryota\|Takiguchi, Shuji\|Mori, Masaki\|Fumoto, Katsumi\|Doki, Yuichiro\|Kikuchi, Akira
PMID:	29563607

171.
Journal:	Oncotarget. 2017 Dec 20;9(18):14084-14098.
Title:	Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer.
Author:	Ma, Yunxia\|Chen, Yuan\|Li, Yong\|Grun, Katja\|Berndt, Alexander\|Zhou, Zhongwei\|Petersen, Iver
PMID:	29581829

172.
Journal:	Mol Cancer Ther. 2018 Jun;17(6):1229-1239.
Title:	Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation.
Author:	Chen, Min-Bin\|Liu, Yuan-Yuan\|Xing, Zhao-Yu\|Zhang, Zhi-Qing\|Jiang, Qin\|Lu, Pei-Hua\|Cao, Cong
PMID:	29592879

173.
Journal:	Cancer Lett. 2018 Jul 1;425:88-100.
Title:	IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness.
Author:	Xu, Wen Wen\|Li, Bin\|Zhao, Jian Fu\|Yang, Jing Ge\|Li, Jun Qi\|Tsao, Sai Wah\|He, Qing-Yu\|Cheung, Annie L M
PMID:	29604392

174.
Journal:	Neurogastroenterol Motil. 2018 Sep;30(9):e13346.
Title:	INPP4B overexpression and c-KIT downregulation in human achalasia.
Author:	Bonora, E\|Bianco, F\|Stanzani, A\|Giancola, F\|Astolfi, A\|Indio, V\|Evangelisti, C\|Martelli, A M\|Boschetti, E\|Lugaresi, M\|Ioannou, A\|Torresan, F\|Stanghellini, V\|Clavenzani, P\|Seri, M\|Moonen, A\|Van Beek, K\|Wouters, M\|Boeckxstaens, G E\|Zaninotto, G\|Mattioli, S\|
PMID:	29644781

175.
Journal:	J Food Sci. 2018 May;83(5):1436-1443.
Title:	Natural Borneol Enhances Paclitaxel-Induced Apoptosis of ESCC Cells by Inactivation of the PI3K/AKT.
Author:	Meng, Xiaofeng\|Dong, Xiaomei\|Wang, Wen\|Yang, Liu\|Zhang, Xia\|Li, Yanfang\|Chen, Tianfeng\|Ma, Hang\|Qi, Da\|Su, Jianyu
PMID:	29660811

176.
Journal:	Molecules. 2018 Apr 17;23(4). pii: molecules23040930.
Title:	Chemoresistance to Cancer Treatment: Benzo-alpha-Pyrene as Friend or Foe?
Author:	Dzobo, Kevin\|Hassen, Naseeha\|Senthebane, Dimakatso Alice\|Thomford, Nicholas Ekow\|Rowe, Arielle\|Shipanga, Hendrina\|Wonkam, Ambroise\|Parker, M Iqbal\|Mowla, Shaheen\|Dandara, Collet
PMID:	29673198

177.
Journal:	Chem Biol Interact. 2018 May 25;288:76-82.
Title:	The CADM2/Akt pathway is involved in the inhibitory effect of miR-21-5p downregulation on proliferation and apoptosis in esophageal squamous cell carcinoma cells.
Author:	Li, Xiaohui\|Chen, Dong\|Li, Mengfei\|Gao, Xiang\|Shi, Gongning\|Zhao, Hui
PMID:	29680210

178.
Journal:	Oncol Rep. 2018 Jun;39(6):2942-2950.
Title:	Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades.
Author:	Wang, Xiaona\|Zhu, Yanyan\|Zhu, Lili\|Chen, Xinhuan\|Xu, Yanyan\|Zhao, Yafei\|Shao, Yingzhe\|Li, Feng\|Jiang, Yanan\|Lu, Jing\|Huang, Youtian\|Chang, Xiaobin\|Zhang, Juan\|Li, Xiang\|Liu, Kangdong\|Zhao, Mingyao\|Dong, Ziming\|Zhao, Jimin
PMID:	29693162

179.
Journal:	Mol Cancer Ther. 2018 Jul;17(7):1540-1553.
Title:	Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo.
Author:	Song, Mengqiu\|Liu, Xuejiao\|Liu, Kangdong\|Zhao, Ran\|Huang, Hai\|Shi, Yuanyuan\|Zhang, Man\|Zhou, Silei\|Xie, Hua\|Chen, Hanyong\|Li, Yin\|Zheng, Yan\|Wu, Qiong\|Liu, Fangfang\|Li, Enmin\|Bode, Ann M\|Dong, Zigang\|Lee, Mee-Hyun
PMID:	29695636

180.
Journal:	Biochem Biophys Res Commun. 2018 Jun 18;501(1):119-123.
Title:	MiR-502 mediates esophageal cancer cell TE1 proliferation by promoting AKT phosphorylation.
Author:	Xu, Jing\|Pan, Xiongxiong\|Hu, Zhendong
PMID:	29709473

181.
Journal:	Oncol Rep. 2018 Jul;40(1):495-503.
Title:	Stable silencing of dll4 gene suppresses the growth and metastasis of esophagus cancer cells by attenuating Akt phosphorylation.
Author:	Guo, Xianzhi\|Duan, Yingchun\|Ye, Xiaolei\|Hu, Lina\|Xu, Tong\|Tong, Li\|Yu, Minghua
PMID:	29749499

182.
Journal:	Cell Death Dis. 2018 May 29;9(6):640.
Title:	miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP.
Author:	Choe, Min Ho\|Yoon, Yina\|Kim, Joon\|Hwang, Sang-Gu\|Han, Young-Hoon\|Kim, Jae-Sung
PMID:	29844307

183.
Journal:	Oncol Rep. 2018 Aug;40(2):1147-1155.
Title:	Gproteincoupled receptor 120 regulates the development and progression of human esophageal cancer.
Author:	Cui, Zhen\|Li, Duojie\|Liu, Jingjing\|Zhang, Yajun\|Xu, Hongbo\|Yin, Hongmei\|Li, Hongwei\|Wang, Gengming\|Cai, Hanfei\|Zhang, Lei\|Duan, Shimiao\|Jiang, Hao
PMID:	29901155

184.
Journal:	Cancer Chemother Pharmacol. 2018 Jun 16. pii: 10.1007/s00280-018-3627-3.
Title:	Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer.
Author:	Guo, Xiao-Fang\|Li, Sai-Sai\|Zhu, Xiao-Fei\|Dou, Qiao-Hua\|Liu, Duan
PMID:	29909520

185.
Journal:	Mol Carcinog. 2018 Jul 23.
Title:	Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways.
Author:	Zhao, Simin\|Jiang, Yanan\|Zhao, Jimin\|Li, Honglin\|Yin, Xueshan\|Wang, Yanhong\|Xie, Yifei\|Chen, Xinhuan\|Lu, Jing\|Dong, Ziming\|Liu, Kangdong
PMID:	30035335

186.
Journal:	Cell Death Dis. 2018 Jul 26;9(8):817.
Title:	Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways.
Author:	Cao, Jinlin\|Lv, Wang\|Wang, Luming\|Xu, Jinming\|Yuan, Ping\|Huang, Sha\|He, Zhehao\|Hu, Jian
PMID:	30050135

187.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Jul;22(14):4532-4541.
Title:	MicroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1.
Author:	Zang, R-K\|Ma, J-B\|Liang, Y-C\|Wang, Y\|Hu, S-L\|Zhang, Y\|Dong, W\|Zhang, W\|Hu, L-K
PMID:	30058693

188.
Journal:	Biomed Pharmacother. 2018 Nov;107:139-145.
Title:	Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival.
Author:	Meng, Lingxin\|Fuhao, Zhu\|Xiaoming, Zhou\|Yuxiu, Zheng\|Zhaojun, Ding\|Bingcheng, Li\|Meiling, Xu\|Shuyan, Sun
PMID:	30086460

189.
Journal:	Cancer Sci. 2018 Aug 10.
Title:	TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.
Author:	Xiong, Dian\|Jin, Chun\|Ye, Xudong\|Qiu, Baiquan\|Jianjun, Xu\|Zhu, Shuqiang\|Xiang, Long\|Wu, Haibo\|Yongbing, Wu
PMID:	30098109

190.
Journal:	J Agric Food Chem. 2018 Sep 5;66(35):9248-9258.
Title:	Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling.
Author:	Xu, Wen Wen\|Zheng, Can-Can\|Huang, Yun-Na\|Chen, Wen-You\|Yang, Qing-Sheng\|Ren, Jia-Yi\|Wang, Yue-Ming\|He, Qing-Yu\|Liao, Hua-Xin\|Li, Bin
PMID:	30113849

191.
Journal:	Gene. 2018 Nov 30;677:308-316.
Title:	Long non-coding RNA LINC01617 promotes proliferation and metastasis of esophageal cancer cells through AKT pathway.
Author:	Zhang, Dan\|Yang, Wei\|Wang, Shuwei\|Wang, Fei\|Liu, Dayong\|Dong, Jingjing\|Zhao, Nan\|Wang, Yunye\|Zhang, Haiyan
PMID:	30120975

192.
Journal:	Oncol Lett. 2018 Sep;16(3):3373-3379.
Title:	Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway.
Author:	Shang, Xiaobin\|Liu, Guoyan\|Zhang, Yuefeng\|Tang, Peng\|Zhang, Hongdian\|Jiang, Hongjing\|Yu, Zhentao
PMID:	30127937

193.
Journal:	Cell Physiol Biochem. 2018;49(1):217-225.
Title:	RUNX2 Plays An Oncogenic Role in Esophageal Carcinoma by Activating the PI3K/AKT and ERK Signaling Pathways.
Author:	Lu, Huibin\|Jiang, Tian\|Ren, Kewei\|Li, Zongming Li\|Ren, Jianzhuang\|Wu, Gang\|Han, Xinwei
PMID:	30138923

194.
Journal:	J Thorac Dis. 2018 Jul;10(7):3983-3991.
Title:	Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy.
Author:	Kai, Jindan\|Wang, Yiqiao\|Xiong, Fei\|Wang, Sheng
PMID:	30174840

195.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5214-5222.
Title:	Long non-coding RNA FAL1 regulated cell proliferation through Akt pathway via targeting PDK1 in esophageal cancer cells.
Author:	Liang, X-S\|Sun, Y\|Liu, T
PMID:	30178844

196.
Journal:	J Cell Biochem. 2018 Sep 19.
Title:	Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways.
Author:	Jiang, Jin-Huan\|Pi, Jiang\|Jin, Hua\|Cai, Ji-Ye
PMID:	30229997

197.
Journal:	Int J Mol Sci. 2018 Sep 20;19(10). pii: ijms19102861.
Title:	The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices.
Author:	Senthebane, Dimakatso Alice\|Jonker, Tina\|Rowe, Arielle\|Thomford, Nicholas Ekow\|Munro, Daniella\|Dandara, Collet\|Wonkam, Ambroise\|Govender, Dhirendra\|Calder, Bridget\|Soares, Nelson C\|Blackburn, Jonathan M\|Parker, M Iqbal\|Dzobo, Kevin
PMID:	30241395

198.
Journal:	Med Sci Monit. 2018 Oct 28;24:7689-7696.
Title:	Long Non-Coding RNA (lncRNA) Growth Arrest Specific 5 (GAS5) Suppresses Esophageal Squamous Cell Carcinoma Cell Proliferation and Migration by Inactivating Phosphatidylinositol 3-kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway.
Author:	Wang, Guojun\|Sun, Junfeng\|Zhao, Hongchao\|Li, Haohao
PMID:	30368517