Primary Site >> Esophagus Cancer
Gene >> AKT1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation. PMID: 10908564 Ref: A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity. PMID: 10910956 |
Ref: Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. PMID: 11316564 |
Ref: Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway. PMID: 14762343 |
Ref: ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. PMID: 16023108 Ref: Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. PMID: 16036916 |
Ref: Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro. PMID: 16508686 Ref: Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. PMID: 16575012 Ref: Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. PMID: 17079462 |
Ref: Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. PMID: 17273761 Ref: The pan-erbB tyrosine kinase inhibitor CI-1033 inhibits human esophageal cancer cells in vitro and in vivo. PMID: 17342332 Ref: IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms. PMID: 17457048 Ref: Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer. PMID: 17622239 Ref: Id-1 activation of PI3K/Akt/NFkappaB signaling pathway and its significance in promoting survival of esophageal cancer cells. PMID: 17638919 Ref: The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. PMID: 17974918 |
Ref: Statins in esophageal cancer cell lines: promising lead? PMID: 18371147 Ref: Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response. PMID: 18845990 Ref: TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. PMID: 19020730 |
Ref: Expression of Akt and Mdm2 in human esophageal squamous cell carcinoma. PMID: 19124015 Ref: Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. PMID: 19164214 Ref: Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis. PMID: 19304953 Ref: Gene expression changes in a chemoresistant model with human esophageal cancer xenografts using cDNA microarray. PMID: 19414360 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. PMID: 19551863 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 |
Ref: A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer. PMID: 19956829 Ref: Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis. PMID: 20028748 Ref: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways. PMID: 20039326 Ref: Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus. PMID: 20104520 Ref: Upregulation of SPRR3 promotes colorectal tumorigenesis. PMID: 20379613 Ref: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. PMID: 20486853 Ref: Expression patterns of astrocyte elevated gene-1 (AEG-1) during development of the mouse embryo. PMID: 20736086 Ref: LATS tumor suppressor: a new governor of cellular homeostasis. PMID: 20935475 |
Ref: Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer. PMID: 20839260 Ref: Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability. PMID: 21082354 Ref: Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. PMID: 21248297 Ref: Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway. PMID: 21310827 Ref: The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. PMID: 21467840 Ref: Phorbol 12,13 dibutyrate behaves in a tumor-inhibitory manner in esophageal adenocarcinoma cell lines. PMID: 21595773 Ref: A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma. PMID: 21707510 Ref: [Inhibition of PDK1 gene expression in esophageal cancer EC9706 cells by RNA interference and its effect on their malignant biological behavior]. PMID: 21875479 Ref: Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells. PMID: 21951621 |
Ref: Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma. PMID: 22293713 Ref: Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma. PMID: 22705009 Ref: Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. PMID: 22753744 Ref: Protein kinase casein kinase 2-mediated upregulation of N-cadherin confers anoikis resistance on esophageal carcinoma cells. PMID: 22767590 Ref: siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin. PMID: 22919244 Ref: [Small interfering RNA in silencing cox-2 expression enhances radiosensitivity of esophageal cancer EC9706 cell]. PMID: 22944132 Ref: Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation. PMID: 22965424 Ref: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. PMID: 22992618 Ref: Silencing of PDK1 gene expression by RNA interference suppresses growth of esophageal cancer. PMID: 23098536 |
Ref: Lapatinib, a dual inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2, potentiates the antitumor effects of cisplatin on esophageal carcinoma. PMID: 22458639 Ref: Inhibition of microRNA-21 increases radiosensitivity of esophageal cancer cells through phosphatase and tensin homolog deleted on chromosome 10 activation. PMID: 22958183 Ref: Cancer genetics and genomics of human FOX family genes. PMID: 23022474 Ref: Effect of miR-451 on the biological behavior of the esophageal carcinoma cell line EC9706. PMID: 23053883 Ref: Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer. PMID: 23064324 Ref: Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway. PMID: 23420294 Ref: PIK3CA mutation is associated with a favorable prognosis among patients with curatively resected esophageal squamous cell carcinoma. PMID: 23532889 Ref: Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation. PMID: 23555162 Ref: OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway. PMID: 23652278 Ref: Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma. PMID: 23663482 Ref: Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression. PMID: 24130695 Ref: PIK3CA hypomethylation plays a key role in activation of the PI3K/AKT pathway in esophageal cancer in Chinese patients. PMID: 24241346 Ref: The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. PMID: 24244023 Ref: A novel chemotherapeutic arene ruthenium(II) drug Rawq01 altered the effect of microRNA-21 on PTEN/AKT signaling pathway in esophageal cancer cells. PMID: 24324076 |
Ref: Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1alpha-induced invasion of human esophageal carcinoma cells. PMID: 23192861 Ref: The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma. PMID: 24026884 Ref: Combination treatment with paclitaxel and doxorubicin inhibits growth of human esophageal squamous cancer cells by inactivation of Akt. PMID: 24247637 Ref: Small molecule agonists of PPAR-gamma exert therapeutic effects in esophageal cancer. PMID: 24272485 Ref: The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway. PMID: 24317439 Ref: XB130 promotes proliferation and invasion of gastric cancer cells. PMID: 24387290 Ref: Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma. PMID: 24434574 Ref: Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy. PMID: 24438628 Ref: EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer. PMID: 24510732 Ref: Id1-induced IGF-II and its autocrine/endocrine promotion of esophageal cancer progression and chemoresistance--implications for IGF-II and IGF-IR-targeted therapy. PMID: 24599933 Ref: p63 regulates growth of esophageal squamous carcinoma cells via the Akt signaling pathway. PMID: 24718831 Ref: Protein tyrosine kinase 7 plays a tumor suppressor role by inhibiting ERK and AKT phosphorylation in lung cancer. PMID: 24789704 Ref: The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. PMID: 24829906 Ref: Talen-mediated girdin knockout downregulates cell proliferation, migration and invasion in human esophageal carcinoma ECA109 cells. PMID: 24865549 Ref: Akt-mediated transforming growth factor-beta1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cells. PMID: 24874843 Ref: Expression of migfilin is increased in esophageal cancer and represses the Akt-beta-catenin activation. PMID: 24959381 Ref: The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells. PMID: 25003315 Ref: ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. PMID: 25091467 Ref: Resistance to cetuximab in EGFR-overexpressing esophageal squamous cell carcinoma xenografts due to FGFR2 amplification and overexpression. PMID: 25242085 Ref: Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. PMID: 25344912 Ref: Licochalcone-A sensitizes human esophageal carcinoma cells to TRAIL-mediated apoptosis by proteasomal degradation of XIAP. PMID: 25436288 Ref: Licochalcone-A sensitizes human esophageal carcinoma cells to TRAIL-mediated apoptosis by proteasomal degradation of XIAP. PMID: 25513073 |
Ref: Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells. PMID: 25333998 Ref: ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts. PMID: 25435423 Ref: Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer. PMID: 25563492 Ref: Inactivation of GSK3beta and activation of NF-kappaB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma. PMID: 25568334 Ref: MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells. PMID: 25637514 Ref: Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloproteinase 2. PMID: 25724186 Ref: Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. PMID: 25733817 Ref: Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair. PMID: 25750543 Ref: MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model. PMID: 25826212 Ref: Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells. PMID: 25853217 Ref: Immunohistochemical and molecular analysis of PI3K/AKT/mTOR pathway in esophageal carcinoma. PMID: 25912437 Ref: Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation. PMID: 26000878 Ref: High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis. PMID: 26124180 Ref: Correction: Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation. PMID: 26173079 Ref: Over-expression of Orai1 mediates cell proliferation and associates with poor prognosis in human non-small cell lung carcinoma. PMID: 26191202 Ref: The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121. PMID: 26235881 Ref: [Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells]. PMID: 26248429 Ref: Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. PMID: 26302489 Ref: IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. PMID: 26317790 Ref: Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation. PMID: 26378019 Ref: Antitumor Activity of Tenacissoside H on Esophageal Cancer through Arresting Cell Cycle and Regulating PI3K/Akt-NF-kappaB Transduction Cascade. PMID: 26495015 Ref: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells. PMID: 26498695 Ref: [The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells]. PMID: 26827544 |
Ref: Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming. PMID: 26148236 Ref: Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway. PMID: 26318432 Ref: Endostatin combined with radiotherapy suppresses vasculogenic mimicry formation through inhibition of epithelial-mesenchymal transition in esophageal cancer. PMID: 26511968 Ref: Regulation of CXCR4/AKT-signaling-induced cell invasion and tumor metastasis by RhoA, Rac-1, and Cdc42 in human esophageal cancer. PMID: 26631033 Ref: Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling. PMID: 26647768 Ref: FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro. PMID: 26833879 Ref: Effect of recombinant human endostatin onradiotherapy for esophagus cancer. PMID: 26851794 Ref: DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma. PMID: 26856390 Ref: Knockdown of DDX46 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma cells. PMID: 27176873 Ref: MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer. PMID: 27188433 Ref: Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. PMID: 27239113 Ref: NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells. PMID: 27317650 Ref: Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells. PMID: 27357907 Ref: Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling. PMID: 27376780 Ref: Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-kappaB and PI3K/Akt signaling pathways. PMID: 27446379 Ref: Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo. PMID: 27453171 Ref: beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro. PMID: 27586268 Ref: Aloe-emodin suppresses esophageal cancer cell TE1 proliferation by inhibiting AKT and ERK phosphorylation. PMID: 27602169 Ref: Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN. PMID: 27644195 Ref: The Synthetic beta-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways. PMID: 27875549 |
Ref: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. PMID: 27857021 Ref: Integrin alpha6 promotes esophageal cancer metastasis and is targeted by miR-92b. PMID: 28036265 Ref: Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells. PMID: 28109079 Ref: RICTOR expression in esophageal squamous cell carcinoma and its clinical significance. PMID: 28132115 Ref: Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis. PMID: 28209530 Ref: Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway. PMID: 28463955 Ref: Berberine displays antitumor activity in esophageal cancer cells in vitro. PMID: 28465635 Ref: A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer. PMID: 28498434 Ref: MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway. PMID: 28498460 Ref: Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway. PMID: 28631572 Ref: Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways. PMID: 28667862 Ref: RACK1 promotes radiation resistance in esophageal cancer via regulating AKT pathway and Bcl-2 expression. PMID: 28760343 Ref: Influence and mechanism of 5-aminolevulinic acid-photodynamic therapy on the metastasis of esophageal carcinoma. PMID: 28811223 Ref: FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. PMID: 28857247 Ref: Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1. PMID: 28899457 Ref: GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways. PMID: 29019267 Ref: Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway. PMID: 29085498 Ref: Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway. PMID: 29093644 Ref: Autophagy inhibition contributes to Endostar sensitization in esophageal squamous cell carcinoma. PMID: 29163691 Ref: Delineation of the HPV11E6 and HPV18E6 Pathways in Initiating Cellular Transformation. PMID: 29164058 Ref: Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling. PMID: 29285246 |
Ref: Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation. PMID: 29059172 Ref: UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. PMID: 29115622 Ref: Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. PMID: 29208461 Ref: HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells. PMID: 29223420 Ref: Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo. PMID: 29290767 Ref: Vitexin induces G2/Mphase arrest and apoptosis via Akt/mTOR signaling pathway in human glioblastoma cells. PMID: 29328424 Ref: Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling. PMID: 29339720 Ref: RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. PMID: 29379302 Ref: Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma. PMID: 29416661 Ref: Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway. PMID: 29435022 Ref: Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers. PMID: 29452214 Ref: Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma. PMID: 29454790 Ref: miR302a inhibits the proliferation of esophageal cancer cells through the MAPK and PI3K/Akt signaling pathways. PMID: 29456742 Ref: The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma. PMID: 29463194 Ref: Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NF-kB/COX-2/VEGF axis. PMID: 29507700 Ref: LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein. PMID: 29511340 Ref: NDRG2 suppresses proliferation, migration, invasion and epithelial-mesenchymal transition of esophageal cancer cells through regulating the AKT/XIAP signaling pathway. PMID: 29530788 Ref: The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma. PMID: 29560108 Ref: Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug. PMID: 29563607 Ref: Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer. PMID: 29581829 Ref: Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation. PMID: 29592879 Ref: IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness. PMID: 29604392 Ref: INPP4B overexpression and c-KIT downregulation in human achalasia. PMID: 29644781 Ref: Natural Borneol Enhances Paclitaxel-Induced Apoptosis of ESCC Cells by Inactivation of the PI3K/AKT. PMID: 29660811 Ref: Chemoresistance to Cancer Treatment: Benzo-alpha-Pyrene as Friend or Foe? PMID: 29673198 Ref: The CADM2/Akt pathway is involved in the inhibitory effect of miR-21-5p downregulation on proliferation and apoptosis in esophageal squamous cell carcinoma cells. PMID: 29680210 Ref: Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades. PMID: 29693162 Ref: Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo. PMID: 29695636 Ref: MiR-502 mediates esophageal cancer cell TE1 proliferation by promoting AKT phosphorylation. PMID: 29709473 Ref: Stable silencing of dll4 gene suppresses the growth and metastasis of esophagus cancer cells by attenuating Akt phosphorylation. PMID: 29749499 Ref: miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP. PMID: 29844307 Ref: Gproteincoupled receptor 120 regulates the development and progression of human esophageal cancer. PMID: 29901155 Ref: Lapatinib in combination with paclitaxel plays synergistic antitumor effects on esophageal squamous cancer. PMID: 29909520 Ref: Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways. PMID: 30035335 Ref: Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways. PMID: 30050135 Ref: MicroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1. PMID: 30058693 Ref: Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival. PMID: 30086460 Ref: TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway. PMID: 30098109 Ref: Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling. PMID: 30113849 Ref: Long non-coding RNA LINC01617 promotes proliferation and metastasis of esophageal cancer cells through AKT pathway. PMID: 30120975 Ref: Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway. PMID: 30127937 Ref: RUNX2 Plays An Oncogenic Role in Esophageal Carcinoma by Activating the PI3K/AKT and ERK Signaling Pathways. PMID: 30138923 Ref: Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy. PMID: 30174840 Ref: Long non-coding RNA FAL1 regulated cell proliferation through Akt pathway via targeting PDK1 in esophageal cancer cells. PMID: 30178844 Ref: Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. PMID: 30229997 Ref: The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices. PMID: 30241395 Ref: Long Non-Coding RNA (lncRNA) Growth Arrest Specific 5 (GAS5) Suppresses Esophageal Squamous Cell Carcinoma Cell Proliferation and Migration by Inactivating Phosphatidylinositol 3-kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. PMID: 30368517 |