Primary Site >> Colorectal Cancer
Gene >> AKT1
| 1. | |||||||||||
| Journal: | J Gastroenterol. 1998 Dec;33(6):842-9. | ||||||||||
| Title: | Characteristics of two cancer cell lines derived from metastatic foci in liver and peritoneum of a patient with colon cancer. | ||||||||||
| Author: | Kotanagi, H|Saito, Y|Yoshioka, T|Koyama, K | ||||||||||
| PMID: | 9853557 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncol Rep. 1999 Jul-Aug;6(4):827-32. | ||||||||||
| Title: | Activity of glycogen synthase kinase-3beta is down-regulated during transient differentiation of human colon cancer HT-29 cells. | ||||||||||
| Author: | Tuhackova, Z|Sloncova, E|Hlavacek, J|Sovova, V|Velek, J | ||||||||||
| PMID: | 10373664 | ||||||||||
| 3. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):799-804. | ||||||||||
| Title: | Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. | ||||||||||
| Author: | Taupin, D R|Kinoshita, K|Podolsky, D K | ||||||||||
| PMID: | 10639160 | ||||||||||
| 4. | |||||||||||
| Journal: | J Biol Chem. 2000 Oct 27;275(43):33951-6. | ||||||||||
| Title: | Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. | ||||||||||
| Author: | Shao, J|Sheng, H|Inoue, H|Morrow, J D|DuBois, R N | ||||||||||
| PMID: | 10930401 | ||||||||||
| 5. | |||||||||||
| Journal: | Science. 2000 Aug 18;289(5482):1194-7. | ||||||||||
| Title: | Asef, a link between the tumor suppressor APC and G-protein signaling. | ||||||||||
| Author: | Kawasaki, Y|Senda, T|Ishidate, T|Koyama, R|Morishita, T|Iwayama, Y|Higuchi, O|Akiyama, T | ||||||||||
| PMID: | 10947987 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2000 Aug 24;19(36):4125-33. | ||||||||||
| Title: | Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone. | ||||||||||
| Author: | Clarke, P A|Hostein, I|Banerji, U|Stefano, F D|Maloney, A|Walton, M|Judson, I|Workman, P | ||||||||||
| PMID: | 10962573 | ||||||||||
| 7. | |||||||||||
| Journal: | Nature. 2000 Aug 24;406(6798):897-902. | ||||||||||
| Title: | Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma. | ||||||||||
| Author: | Sasaki, T|Irie-Sasaki, J|Horie, Y|Bachmaier, K|Fata, J E|Li, M|Suzuki, A|Bouchard, D|Ho, A|Redston, M|Gallinger, S|Khokha, R|Mak, T W|Hawkins, P T|Stephens, L|Scherer, S W|Tsao, M|Penninger, J M | ||||||||||
| PMID: | 10972292 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 2000 Nov 1;60(21):6201-7. | ||||||||||
| Title: | Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy. | ||||||||||
| Author: | Izuishi, K|Kato, K|Ogura, T|Kinoshita, T|Esumi, H | ||||||||||
| PMID: | 11085546 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2001 Apr 5;20(15):1913-22. | ||||||||||
| Title: | Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody. | ||||||||||
| Author: | Liu, B|Fang, M|Lu, Y|Mendelsohn, J|Fan, Z | ||||||||||
| PMID: | 11313939 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2001 May 15;61(10):4003-9. | ||||||||||
| Title: | Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. | ||||||||||
| Author: | Hostein, I|Robertson, D|DiStefano, F|Workman, P|Clarke, P A | ||||||||||
| PMID: | 11358818 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2001 Jul 1;61(13):5275-83. | ||||||||||
| Title: | A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells. | ||||||||||
| Author: | Bates, R C|Edwards, N S|Burns, G F|Fisher, D E | ||||||||||
| PMID: | 11431370 | ||||||||||
| 12. | |||||||||||
| Journal: | Exp Cell Res. 2001 Aug 15;268(2):139-49. | ||||||||||
| Title: | Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29. | ||||||||||
| Author: | Bauvy, C|Gane, P|Arico, S|Codogno, P|Ogier-Denis, E | ||||||||||
| PMID: | 11478840 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biol Chem. 2001 Oct 12;276(41):37879-86. | ||||||||||
| Title: | Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach. | ||||||||||
| Author: | Burns, T F|El-Deiry, W S | ||||||||||
| PMID: | 11486001 | ||||||||||
| 14. | |||||||||||
| Journal: | Pathobiology. 2001;69(2):86-95. | ||||||||||
| Title: | Interleukin-15 expression is associated with malignant potential in colon cancer cells. | ||||||||||
| Author: | Kuniyasu, H|Oue, N|Nakae, D|Tsutsumi, M|Denda, A|Tsujiuchi, T|Yokozaki, H|Yasui, W | ||||||||||
| PMID: | 11752902 | ||||||||||
| 15. | |||||||||||
| Journal: | Angiogenesis. 2001;4(2):155-62. | ||||||||||
| Title: | Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway. | ||||||||||
| Author: | Jung, Y D|Liu, W|Reinmuth, N|Ahmad, S A|Fan, F|Gallick, G E|Ellis, L M | ||||||||||
| PMID: | 11806247 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Cancer Ther. 2001 Nov;1(1):29-41. | ||||||||||
| Title: | Inhibition of Kirsten-ras expression in human colorectal cancer using rationally selected Kirsten-ras antisense oligonucleotides. | ||||||||||
| Author: | Ross, P J|George, M|Cunningham, D|DiStefano, F|Andreyev, H J|Workman, P|Clarke, P A | ||||||||||
| PMID: | 12467236 | ||||||||||
| 17. | |||||||||||
| Journal: | Carcinogenesis. 2002 Jan;23(1):201-5. | ||||||||||
| Title: | AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis. | ||||||||||
| Author: | Roy, Hemant K|Olusola, Bola F|Clemens, Dahn L|Karolski, William J|Ratashak, Anne|Lynch, Henry T|Smyrk, Thomas C | ||||||||||
| PMID: | 11756242 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncogene. 2002 Jan 3;21(1):78-86. | ||||||||||
| Title: | Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells. | ||||||||||
| Author: | Venkateswarlu, Srinivas|Dawson, Dawn M|St Clair, Patricia|Gupta, Anjana|Willson, James K V|Brattain, Michael G | ||||||||||
| PMID: | 11791178 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2002 Jan 17;21(3):337-46. | ||||||||||
| Title: | Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway. | ||||||||||
| Author: | Nam, Seon Young|Amoscato, Andrew A|Lee, Yong J | ||||||||||
| PMID: | 11821946 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Cancer. 2002 Apr 10;98(5):665-73. | ||||||||||
| Title: | Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation. | ||||||||||
| Author: | Ewton, Daina Z|Kansra, Sanjay|Lim, Seunghwan|Friedman, Eileen | ||||||||||
| PMID: | 11920634 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Death Differ. 2002 Jul;9(7):768-79. | ||||||||||
| Title: | Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism. | ||||||||||
| Author: | Garrouste, F|Remacle-Bonnet, M|Fauriat, C|Marvaldi, J|Luis, J|Pommier, G | ||||||||||
| PMID: | 12058282 | ||||||||||
| 22. | |||||||||||
| Journal: | Clin Cancer Res. 2002 Jun;8(6):1957-63. | ||||||||||
| Title: | The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY294002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells. | ||||||||||
| Author: | Semba, Shuho|Itoh, Nanami|Ito, Masafumi|Harada, Masaru|Yamakawa, Mitsunori | ||||||||||
| PMID: | 12060641 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Res. 2002 Jun 15;62(12):3402-7. | ||||||||||
| Title: | A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis. | ||||||||||
| Author: | Casanova, M Llanos|Larcher, Fernando|Casanova, Benito|Murillas, Rodolfo|Fernandez-Acenero, M Jesus|Villanueva, Concepcion|Martinez-Palacio, Jesus|Ullrich, Axel|Conti, Claudio J|Jorcano, Jose Luis | ||||||||||
| PMID: | 12067982 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer. 2002 Jun 15;94(12):3127-34. | ||||||||||
| Title: | Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma. | ||||||||||
| Author: | Itoh, Nanami|Semba, Shuho|Ito, Masafumi|Takeda, Hiroaki|Kawata, Sumio|Yamakawa, Mitsunori | ||||||||||
| PMID: | 12115344 | ||||||||||
| 25. | |||||||||||
| Journal: | J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24. | ||||||||||
| Title: | Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells. | ||||||||||
| Author: | Wang, Qingding|Wang, Xiaofu|Hernandez, Ambrosio|Hellmich, Mark R|Gatalica, Zoran|Evers, B Mark | ||||||||||
| PMID: | 12140294 | ||||||||||
| 26. | |||||||||||
| Journal: | J Biol Chem. 2002 Oct 11;277(41):38013-20. Epub 2002 Jul 26. | ||||||||||
| Title: | Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. | ||||||||||
| Author: | Ghatak, Shibnath|Misra, Suniti|Toole, Bryan P | ||||||||||
| PMID: | 12145277 | ||||||||||
| 27. | |||||||||||
| Journal: | Am J Pathol. 2002 Aug;161(2):439-47. | ||||||||||
| Title: | PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers. | ||||||||||
| Author: | Zhou, Xiao-Ping|Loukola, Anu|Salovaara, Reijo|Nystrom-Lahti, Minna|Peltomaki, Paivi|de la Chapelle, Albert|Aaltonen, Lauri A|Eng, Charis | ||||||||||
| PMID: | 12163369 | ||||||||||
| 28. | |||||||||||
| Journal: | J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19. | ||||||||||
| Title: | Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. | ||||||||||
| Author: | Hsi, Linda C|Wilson, Leigh C|Eling, Thomas E | ||||||||||
| PMID: | 12189136 | ||||||||||
| 29. | |||||||||||
| Journal: | Pharmacol Ther. 2002 Feb-Mar;93(2-3):233-42. | ||||||||||
| Title: | Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. | ||||||||||
| Author: | Yoganathan, N|Yee, A|Zhang, Z|Leung, D|Yan, J|Fazli, L|Kojic, D L|Costello, P C|Jabali, M|Dedhar, S|Sanghera, J | ||||||||||
| PMID: | 12191615 | ||||||||||
| 30. | |||||||||||
| Journal: | FASEB J. 2002 Oct;16(12):1642-4. | ||||||||||
| Title: | Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice. | ||||||||||
| Author: | Guerrero, Silvia|Figueras, Agnes|Casanova, Isolda|Farre, Lourdes|Lloveras, Belen|Capella, Gabriel|Trias, Manuel|Mangues, Ramon | ||||||||||
| PMID: | 12207005 | ||||||||||
| 31. | |||||||||||
| Journal: | Gastroenterology. 2002 Oct;123(4):1191-204. | ||||||||||
| Title: | Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines. | ||||||||||
| Author: | Adachi, Yasushi|Lee, Choon-Taek|Coffee, Keith|Yamagata, Noboru|Ohm, Joyce E|Park, Kyung-Ho|Dikov, Mikhail M|Nadaf, Sorena R|Arteaga, Carlos L|Carbone, David P | ||||||||||
| PMID: | 12360481 | ||||||||||
| 32. | |||||||||||
| Journal: | Clin Cancer Res. 2002 Oct;8(10):3250-8. | ||||||||||
| Title: | Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa). | ||||||||||
| Author: | Bianco, Cataldo|Tortora, Giampaolo|Bianco, Roberto|Caputo, Roberta|Veneziani, Bianca Maria|Caputo, Rosa|Damiano, Vincenzo|Troiani, Teresa|Fontanini, Gabriella|Raben, David|Pepe, Stefano|Bianco, A Raffaele|Ciardiello, Fortunato | ||||||||||
| PMID: | 12374696 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncogene. 2002 Nov 7;21(51):7797-807. | ||||||||||
| Title: | Src activation regulates anoikis in human colon tumor cell lines. | ||||||||||
| Author: | Windham, T Christopher|Parikh, Nila U|Siwak, Doris R|Summy, Justin M|McConkey, David J|Kraker, Alan J|Gallick, Gary E | ||||||||||
| PMID: | 12420216 | ||||||||||
| 34. | |||||||||||
| Journal: | Br Med Bull. 2002;64:227-54. | ||||||||||
| Title: | Therapeutics targeting signal transduction for patients with colorectal carcinoma. | ||||||||||
| Author: | de Bono, Johann S|Rowinsky, Eric K | ||||||||||
| PMID: | 12421735 | ||||||||||
| 35. | |||||||||||
| Journal: | Clin Cancer Res. 2002 Dec;8(12):3824-31. | ||||||||||
| Title: | Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma. | ||||||||||
| Author: | Semba, Shuho|Itoh, Nanami|Ito, Masafumi|Youssef, Emile M|Harada, Masaru|Moriya, Toshiyuki|Kimura, Wataru|Yamakawa, Mitsunori | ||||||||||
| PMID: | 12473596 | ||||||||||
| 36. | |||||||||||
| Journal: | J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):213-28. | ||||||||||
| Title: | Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate. | ||||||||||
| Author: | Schnyder, Bruno|Lahm, Harald|Pittet, Martine|Schnyder-Candrian, Silvia | ||||||||||
| PMID: | 12503617 | ||||||||||
| 37. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G996-1005. Epub 2003 Feb | ||||||||||
| Title: | Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line. | ||||||||||
| Author: | Cho, Han J|Kim, Woo K|Kim, Eun J|Jung, Kyeong C|Park, Soochul|Lee, Hyun S|Tyner, Angela L|Park, Jung H Y | ||||||||||
| PMID: | 12571082 | ||||||||||
| 38. | |||||||||||
| Journal: | Int J Cancer. 2003 May 10;104(6):722-7. | ||||||||||
| Title: | Differential effects between amphoterin and advanced glycation end products on colon cancer cells. | ||||||||||
| Author: | Kuniyasu, Hiroki|Chihara, Yoshitomo|Kondo, Hideaki | ||||||||||
| PMID: | 12640679 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Res. 2003 May 1;63(9):2330-4. | ||||||||||
| Title: | Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. | ||||||||||
| Author: | Fukuda, Ryo|Kelly, Brian|Semenza, Gregg L | ||||||||||
| PMID: | 12727858 | ||||||||||
| 40. | |||||||||||
| Journal: | Mol Pharmacol. 2003 Jun;63(6):1281-8. | ||||||||||
| Title: | Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist. | ||||||||||
| Author: | Burbridge, Mike F|Venot, Virginie|Casara, Patrick J|Perron-Sierra, Francoise|Hickman, John A|Tucker, Gordon C | ||||||||||
| PMID: | 12761337 | ||||||||||
| 41. | |||||||||||
| Journal: | Semin Oncol. 2003 Jun;30(3 Suppl 6):56-67. | ||||||||||
| Title: | Signaling inhibition with radiation in colorectal cancer: clinical trials. | ||||||||||
| Author: | McKenna, W Gillies|Muschel, Ruth J|Gupta, Anjali|Hahn, Stephen|Bernhard, Eric J | ||||||||||
| PMID: | 12802796 | ||||||||||
| 42. | |||||||||||
| Journal: | J Biol Chem. 2003 Sep 12;278(37):35451-7. Epub 2003 Jun 24. | ||||||||||
| Title: | Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. | ||||||||||
| Author: | Buchanan, F Gregory|Wang, Dingzhi|Bargiacchi, Francesca|DuBois, Raymond N | ||||||||||
| PMID: | 12824187 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Res. 2003 Jul 1;63(13):3632-6. | ||||||||||
| Title: | Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. | ||||||||||
| Author: | Liu, Wenbiao|Reinmuth, Niels|Stoeltzing, Oliver|Parikh, Alexander A|Tellez, Carmen|Williams, Simon|Jung, Young D|Fan, Fan|Takeda, Akihiko|Akagi, Morihisa|Bar-Eli, Menashe|Gallick, Gary E|Ellis, Lee M | ||||||||||
| PMID: | 12839952 | ||||||||||
| 44. | |||||||||||
| Journal: | Int J Oncol. 2003 Aug;23(2):503-8. | ||||||||||
| Title: | Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK. | ||||||||||
| Author: | Lee, Eun Ju|Park, Hye Geong|Kang, Ho Sung | ||||||||||
| PMID: | 12851702 | ||||||||||
| 45. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Jul;9(7):2457-64. | ||||||||||
| Title: | A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. | ||||||||||
| Author: | Daneshmand, Manijeh|Parolin, Doris A E|Hirte, Holger W|Major, Pierre|Goss, Glenwood|Stewart, David|Batist, Gerald|Miller, Wilson H Jr|Matthews, Sarah|Seymour, Lesley|Lorimer, Ian A J | ||||||||||
| PMID: | 12855618 | ||||||||||
| 46. | |||||||||||
| Journal: | J Nutr. 2003 Aug;133(8):2675-81. | ||||||||||
| Title: | Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. | ||||||||||
| Author: | Kim, Eun Ji|Kang, Il-Jun|Cho, Han Jin|Kim, Woo Kyoung|Ha, Yeong-Lae|Park, Jung Han Yoon | ||||||||||
| PMID: | 12888657 | ||||||||||
| 47. | |||||||||||
| Journal: | Mol Cancer Res. 2003 Aug;1(10):755-64. | ||||||||||
| Title: | Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines. | ||||||||||
| Author: | Golubovskaya, Vita M|Gross, Steven|Kaur, Aparna S|Wilson, Richard I|Xu, Li-Hui|Yang, Xi Hui|Cance, William G | ||||||||||
| PMID: | 12939401 | ||||||||||
| 48. | |||||||||||
| Journal: | Int J Mol Med. 2003 Oct;12(4):633-41. | ||||||||||
| Title: | Induction of macrophage migration inhibitory factor by lysophosphatidic acid: relevance to tumor growth and angiogenesis. | ||||||||||
| Author: | Sun, Bailong|Nishihira, Jun|Suzuki, Masaki|Fukushima, Nobuyuki|Ishibashi, Teruo|Kondo, Masao|Sato, Yuji|Todo, Satoru | ||||||||||
| PMID: | 12964047 | ||||||||||
| 49. | |||||||||||
| Journal: | Gut. 2003 Oct;52(10):1472-8. | ||||||||||
| Title: | Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. | ||||||||||
| Author: | Sheng, H|Shao, J|Townsend, C M Jr|Evers, B M | ||||||||||
| PMID: | 12970141 | ||||||||||
| 50. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Oct 15;9(13):4802-10. | ||||||||||
| Title: | Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. | ||||||||||
| Author: | Kuniyasu, Hiroki|Ohmori, Hitoshi|Sasaki, Takamistu|Sasahira, Tomonori|Yoshida, Kazuhiro|Kitadai, Yasuhiko|Fidler, Isaiah J | ||||||||||
| PMID: | 14581351 | ||||||||||
| 51. | |||||||||||
| Journal: | Cancer Res. 2003 Oct 15;63(20):6726-34. | ||||||||||
| Title: | Inhibition of angiotensin II activity enhanced the antitumor effect of cyclooxygenase-2 inhibitors via insulin-like growth factor I receptor pathway. | ||||||||||
| Author: | Yasumaru, Masakazu|Tsuji, Shingo|Tsujii, Masahiko|Irie, Takanobu|Komori, Masato|Kimura, Arata|Nishida, Tsutomu|Kakiuchi, Yoshimi|Kawai, Naoki|Murata, Hiroaki|Horimoto, Masayoshi|Sasaki, Yutaka|Hayashi, Norio|Kawano, Sunao|Hori, Masatsugu | ||||||||||
| PMID: | 14583467 | ||||||||||
| 52. | |||||||||||
| Journal: | Cancer Gene Ther. 2003 Nov;10(11):803-13. | ||||||||||
| Title: | Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells. | ||||||||||
| Author: | Saito, Yuji|Gopalan, Began|Mhashilkar, Abner M|Roth, Jack A|Chada, Sunil|Zumstein, Louis|Ramesh, Rajagopal | ||||||||||
| PMID: | 14605666 | ||||||||||
| 53. | |||||||||||
| Journal: | Nat Genet. 2003 Dec;35(4):323-30. Epub 2003 Nov 16. | ||||||||||
| Title: | Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice. | ||||||||||
| Author: | Aoki, Koji|Tamai, Yoshitaka|Horiike, Shigeo|Oshima, Masanobu|Taketo, Makoto M | ||||||||||
| PMID: | 14625550 | ||||||||||
| 54. | |||||||||||
| Journal: | Cancer Res. 2003 Nov 15;63(22):7708-16. | ||||||||||
| Title: | Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway. | ||||||||||
| Author: | Sekharam, Madhavi|Zhao, Haiyan|Sun, Mei|Fang, Quan|Zhang, Qingbo|Yuan, Zengqiang|Dan, Han C|Boulware, David|Cheng, Jin Q|Coppola, Domenico | ||||||||||
| PMID: | 14633695 | ||||||||||
| 55. | |||||||||||
| Journal: | Eur J Cancer Prev. 2003 Dec;12(6):469-78. | ||||||||||
| Title: | The in vitro effects of H-89, a specific inhibitor of protein kinase A, in the human colonic carcinoma cell line Caco-2. | ||||||||||
| Author: | Bockmann, S|Nebe, B | ||||||||||
| PMID: | 14639124 | ||||||||||
| 56. | |||||||||||
| Journal: | Cancer Res. 2003 Dec 15;63(24):8600-5. | ||||||||||
| Title: | Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling. | ||||||||||
| Author: | Rakitina, Tatiana V|Vasilevskaya, Irina A|O'Dwyer, Peter J | ||||||||||
| PMID: | 14695170 | ||||||||||
| 57. | |||||||||||
| Journal: | Horm Metab Res. 2003 Nov-Dec;35(11-12):850-6. | ||||||||||
| Title: | Inhibition of the biologic response to insulin-like growth factor I in MCF-7 breast cancer cells by a new monoclonal antibody to the insulin-like growth factor-I receptor. The importance of receptor down-regulation. | ||||||||||
| Author: | Jackson-Booth, P-G|Terry, C|Lackey, B|Lopaczynska, M|Nissley, P | ||||||||||
| PMID: | 14710368 | ||||||||||
| 58. | |||||||||||
| Journal: | Carcinogenesis. 2004 Feb;25(2):241-8. | ||||||||||
| Title: | Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma. | ||||||||||
| Author: | Khaleghpour, Kianoush|Li, Yang|Banville, Denis|Yu, Zhenbao|Shen, Shi-Hsiang | ||||||||||
| PMID: | 14578160 | ||||||||||
| 59. | |||||||||||
| Journal: | FASEB J. 2004 Jan;18(1):140-2. Epub 2003 Nov 20. | ||||||||||
| Title: | Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion. | ||||||||||
| Author: | Nubel, Tobias|Dippold, Wolfgang|Kleinert, Hartmut|Kaina, Bernd|Fritz, Gerhard | ||||||||||
| PMID: | 14630701 | ||||||||||
| 60. | |||||||||||
| Journal: | Oncogene. 2004 Apr 1;23(14):2465-71. | ||||||||||
| Title: | An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B. | ||||||||||
| Author: | Fishman, Pnina|Bar-Yehuda, Sara|Ohana, Gil|Barer, Faina|Ochaion, Avivit|Erlanger, Abigail|Madi, Lea | ||||||||||
| PMID: | 14691449 | ||||||||||
| 61. | |||||||||||
| Journal: | Oncogene. 2004 Jan 15;23(2):617-28. | ||||||||||
| Title: | PTEN mutations are common in sporadic microsatellite stable colorectal cancer. | ||||||||||
| Author: | Nassif, Najah T|Lobo, Glenn P|Wu, Xiaojuan|Henderson, Christopher J A|Morrison, Carl D|Eng, Charis|Jalaludin, Bin|Segelov, Eva | ||||||||||
| PMID: | 14724591 | ||||||||||
| 62. | |||||||||||
| Journal: | Cancer Res. 2004 Jan 15;64(2):665-71. | ||||||||||
| Title: | Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3. | ||||||||||
| Author: | Miyamoto, Shin'ichi|Yano, Keiichi|Sugimoto, Seiji|Ishii, Genichiro|Hasebe, Takahiro|Endoh, Yasushi|Kodama, Keiji|Goya, Masato|Chiba, Tsutomu|Ochiai, Atsushi | ||||||||||
| PMID: | 14744783 | ||||||||||
| 63. | |||||||||||
| Journal: | Clin Cancer Res. 2004 Jan 15;10(2):784-93. | ||||||||||
| Title: | Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. | ||||||||||
| Author: | Ciardiello, Fortunato|Bianco, Roberto|Caputo, Roberta|Caputo, Rosa|Damiano, Vincenzo|Troiani, Teresa|Melisi, Davide|De Vita, Ferdinando|De Placido, Sabino|Bianco, A Raffaele|Tortora, Giampaolo | ||||||||||
| PMID: | 14760102 | ||||||||||
| 64. | |||||||||||
| Journal: | Am J Pathol. 2004 Mar;164(3):987-95. | ||||||||||
| Title: | ARK5 expression in colorectal cancer and its implications for tumor progression. | ||||||||||
| Author: | Kusakai, Gen-ichi|Suzuki, Atsushi|Ogura, Tsutomu|Miyamoto, Sin'ichi|Ochiai, Atsushi|Kaminishi, Michio|Esumi, Hiroyasu | ||||||||||
| PMID: | 14982852 | ||||||||||
| 65. | |||||||||||
| Journal: | Cancer Res. 2004 Apr 1;64(7):2601-9. | ||||||||||
| Title: | Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. | ||||||||||
| Author: | Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G | ||||||||||
| PMID: | 15059917 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer Cell. 2004 Apr;5(4):329-39. | ||||||||||
| Title: | Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. | ||||||||||
| Author: | Bao, Shideng|Ouyang, Gaoliang|Bai, Xuefang|Huang, Zhi|Ma, Chaoyu|Liu, Ming|Shao, Rong|Anderson, Ryan M|Rich, Jeremy N|Wang, Xiao-Fan | ||||||||||
| PMID: | 15093540 | ||||||||||
| 67. | |||||||||||
| Journal: | Clin Cancer Res. 2004 May 15;10(10):3448-56. | ||||||||||
| Title: | Pak-1 expression increases with progression of colorectal carcinomas to metastasis. | ||||||||||
| Author: | Carter, Julia H|Douglass, Larry E|Deddens, James A|Colligan, Bruce M|Bhatt, Tejal R|Pemberton, Jackson O|Konicek, Susan|Hom, Joanne|Marshall, Mark|Graff, Jeremy R | ||||||||||
| PMID: | 15161701 | ||||||||||
| 68. | |||||||||||
| Journal: | Cancer Res. 2004 Jun 1;64(11):4018-23. | ||||||||||
| Title: | Cripto: a novel target for antibody-based cancer immunotherapy. | ||||||||||
| Author: | Xing, Pei Xiang|Hu, Xiu Feng|Pietersz, Geoffrey A|Hosick, Howard L|McKenzie, Ian F C | ||||||||||
| PMID: | 15173016 | ||||||||||
| 69. | |||||||||||
| Journal: | Semin Oncol. 2004 Apr;31(2 Suppl 7):36-44. | ||||||||||
| Title: | COX-2 inhibitors and other nonsteroidal anti-inflammatory drugs in genitourinary cancer. | ||||||||||
| Author: | Sabichi, Anita L|Lippman, Scott M | ||||||||||
| PMID: | 15179622 | ||||||||||
| 70. | |||||||||||
| Journal: | Cancer Lett. 2004 Jul 16;210(2):139-50. | ||||||||||
| Title: | Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma. | ||||||||||
| Author: | Khor, Tin Oo|Gul, Yunus A|Ithnin, Hairuszah|Seow, Heng Fong | ||||||||||
| PMID: | 15183529 | ||||||||||
| 71. | |||||||||||
| Journal: | Mol Cancer Ther. 2004 Jun;3(6):755-62. | ||||||||||
| Title: | Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase. | ||||||||||
| Author: | Mallon, Robert|Feldberg, Larry|Kim, Steven|Collins, Karen|Wojciechowicz, Donald|Kohler, Constance|Kovacs, Diana|Discafani, Carolyn|Zhang, Nan|Wu, Biqi|Floyd, Brawner|Powell, Dennis|Berger, Dan | ||||||||||
| PMID: | 15210862 | ||||||||||
| 72. | |||||||||||
| Journal: | Exp Mol Pathol. 2004 Aug;77(1):18-25. | ||||||||||
| Title: | CD44 promotes resistance to apoptosis in human colon cancer cells. | ||||||||||
| Author: | Lakshman, Minalini|Subramaniam, Venkateswaran|Rubenthiran, Umayal|Jothy, Serge | ||||||||||
| PMID: | 15215046 | ||||||||||
| 73. | |||||||||||
| Journal: | Mol Cancer Ther. 2004 Jul;3(7):763-72. | ||||||||||
| Title: | Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling. | ||||||||||
| Author: | Ihle, Nathan T|Williams, Ryan|Chow, Sherry|Chew, Wade|Berggren, Margareta I|Paine-Murrieta, Gillian|Minion, Daniel J|Halter, Robert J|Wipf, Peter|Abraham, Robert|Kirkpatrick, Lynn|Powis, Garth | ||||||||||
| PMID: | 15252137 | ||||||||||
| 74. | |||||||||||
| Journal: | Oncogene. 2004 Sep 16;23(42):7067-75. | ||||||||||
| Title: | Regulation of caspase-6 and FLIP by the AMPK family member ARK5. | ||||||||||
| Author: | Suzuki, Atsushi|Kusakai, Gen-Ichi|Kishimoto, Atsuhiro|Shimojo, Yosuke|Miyamoto, Sinichi|Ogura, Tsutomu|Ochiai, Atsushi|Esumi, Hiroyasu | ||||||||||
| PMID: | 15273717 | ||||||||||
| 75. | |||||||||||
| Journal: | Steroids. 2004 Aug;69(8-9):517-22. | ||||||||||
| Title: | Rapid signalling pathway activation by androgens in epithelial and stromal cells. | ||||||||||
| Author: | Castoria, Gabriella|Lombardi, Maria|Barone, Maria Vittoria|Bilancio, Antonio|Di Domenico, Marina|De Falco, Antonietta|Varricchio, Lilian|Bottero, Daniela|Nanayakkara, Merlin|Migliaccio, Antimo|Auricchio, Ferdinando | ||||||||||
| PMID: | 15288763 | ||||||||||
| 76. | |||||||||||
| Journal: | J Biol Chem. 2004 Oct 8;279(41):43261-72. Epub 2004 Aug 4. | ||||||||||
| Title: | Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice. | ||||||||||
| Author: | Moran, Amy E|Hunt, Daniel H|Javid, Sara H|Redston, Mark|Carothers, Adelaide M|Bertagnolli, Monica M | ||||||||||
| PMID: | 15294912 | ||||||||||
| 77. | |||||||||||
| Journal: | Cancer Sci. 2004 Aug;95(8):685-90. | ||||||||||
| Title: | Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-qu inolinium pamoate salt, showing preferential cytotoxicity during glucose starvation. | ||||||||||
| Author: | Esumi, Hiroyasu|Lu, Jie|Kurashima, Yukiko|Hanaoka, Tomoyuki | ||||||||||
| PMID: | 15298733 | ||||||||||
| 78. | |||||||||||
| Journal: | Surgery. 2004 Aug;136(2):143-9. | ||||||||||
| Title: | Inhibition of alpha5 integrin decreases PI3K activation and cell adhesion of human colon cancers. | ||||||||||
| Author: | Murillo, Carlos A|Rychahou, Piotr G|Evers, B Mark | ||||||||||
| PMID: | 15300173 | ||||||||||
| 79. | |||||||||||
| Journal: | J Biol Chem. 2004 Oct 29;279(44):45721-7. Epub 2004 Aug 18. | ||||||||||
| Title: | MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. | ||||||||||
| Author: | Yin, Li|Huang, Lei|Kufe, Donald | ||||||||||
| PMID: | 15322085 | ||||||||||
| 80. | |||||||||||
| Journal: | Front Biosci. 2004 Sep 1;9:2697-713. | ||||||||||
| Title: | Prevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applications. | ||||||||||
| Author: | Chu, Arthur J|Chou, Ta-Hsu|Chen, Ben D | ||||||||||
| PMID: | 15353307 | ||||||||||
| 81. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2004 Jun;23(2):263-8. | ||||||||||
| Title: | Strong association of ARK5 with tumor invasion and metastasis. | ||||||||||
| Author: | Kusakai, G|Suzuki, A|Ogura, T|Kaminishi, M|Esumi, H | ||||||||||
| PMID: | 15354411 | ||||||||||
| 82. | |||||||||||
| Journal: | Int J Oncol. 2004 Oct;25(4):1013-20. | ||||||||||
| Title: | CRIPTO-1: a novel target for therapeutic intervention in human carcinoma. | ||||||||||
| Author: | Normanno, Nicola|De Luca, Antonella|Maiello, Monica R|Bianco, Caterina|Mancino, Mario|Strizzi, Luigi|Arra, Claudio|Ciardiello, Fortunato|Agrawal, Sudhir|Salomon, David S | ||||||||||
| PMID: | 15375551 | ||||||||||
| 83. | |||||||||||
| Journal: | J Biol Chem. 2004 Nov 26;279(48):49617-23. Epub 2004 Sep 17. | ||||||||||
| Title: | |||||||||||