Primary Site >> Colorectal Cancer

Gene >> AKT1

Journal: J Gastroenterol. 1998 Dec;33(6):842-9.
Title: Characteristics of two cancer cell lines derived from metastatic foci in liver and peritoneum of a patient with colon cancer.
Author: Kotanagi, H|Saito, Y|Yoshioka, T|Koyama, K
PMID: 9853557
Journal: Oncol Rep. 1999 Jul-Aug;6(4):827-32.
Title: Activity of glycogen synthase kinase-3beta is down-regulated during transient differentiation of human colon cancer HT-29 cells.
Author: Tuhackova, Z|Sloncova, E|Hlavacek, J|Sovova, V|Velek, J
PMID: 10373664
Journal: Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):799-804.
Title: Intestinal trefoil factor confers colonic epithelial resistance to apoptosis.
Author: Taupin, D R|Kinoshita, K|Podolsky, D K
PMID: 10639160
Journal: J Biol Chem. 2000 Oct 27;275(43):33951-6.
Title: Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells.
Author: Shao, J|Sheng, H|Inoue, H|Morrow, J D|DuBois, R N
PMID: 10930401
Journal: Science. 2000 Aug 18;289(5482):1194-7.
Title: Asef, a link between the tumor suppressor APC and G-protein signaling.
Author: Kawasaki, Y|Senda, T|Ishidate, T|Koyama, R|Morishita, T|Iwayama, Y|Higuchi, O|Akiyama, T
PMID: 10947987
Journal: Oncogene. 2000 Aug 24;19(36):4125-33.
Title: Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.
Author: Clarke, P A|Hostein, I|Banerji, U|Stefano, F D|Maloney, A|Walton, M|Judson, I|Workman, P
PMID: 10962573
Journal: Nature. 2000 Aug 24;406(6798):897-902.
Title: Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma.
Author: Sasaki, T|Irie-Sasaki, J|Horie, Y|Bachmaier, K|Fata, J E|Li, M|Suzuki, A|Bouchard, D|Ho, A|Redston, M|Gallinger, S|Khokha, R|Mak, T W|Hawkins, P T|Stephens, L|Scherer, S W|Tsao, M|Penninger, J M
PMID: 10972292
Journal: Cancer Res. 2000 Nov 1;60(21):6201-7.
Title: Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy.
Author: Izuishi, K|Kato, K|Ogura, T|Kinoshita, T|Esumi, H
PMID: 11085546
Journal: Oncogene. 2001 Apr 5;20(15):1913-22.
Title: Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
Author: Liu, B|Fang, M|Lu, Y|Mendelsohn, J|Fan, Z
PMID: 11313939
Journal: Cancer Res. 2001 May 15;61(10):4003-9.
Title: Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.
Author: Hostein, I|Robertson, D|DiStefano, F|Workman, P|Clarke, P A
PMID: 11358818
Journal: Cancer Res. 2001 Jul 1;61(13):5275-83.
Title: A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells.
Author: Bates, R C|Edwards, N S|Burns, G F|Fisher, D E
PMID: 11431370
Journal: Exp Cell Res. 2001 Aug 15;268(2):139-49.
Title: Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.
Author: Bauvy, C|Gane, P|Arico, S|Codogno, P|Ogier-Denis, E
PMID: 11478840
Journal: J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title: Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author: Burns, T F|El-Deiry, W S
PMID: 11486001
Journal: Pathobiology. 2001;69(2):86-95.
Title: Interleukin-15 expression is associated with malignant potential in colon cancer cells.
Author: Kuniyasu, H|Oue, N|Nakae, D|Tsutsumi, M|Denda, A|Tsujiuchi, T|Yokozaki, H|Yasui, W
PMID: 11752902
Journal: Angiogenesis. 2001;4(2):155-62.
Title: Vascular endothelial growth factor is upregulated by interleukin-1 beta in human vascular smooth muscle cells via the P38 mitogen-activated protein kinase pathway.
Author: Jung, Y D|Liu, W|Reinmuth, N|Ahmad, S A|Fan, F|Gallick, G E|Ellis, L M
PMID: 11806247
Journal: Mol Cancer Ther. 2001 Nov;1(1):29-41.
Title: Inhibition of Kirsten-ras expression in human colorectal cancer using rationally selected Kirsten-ras antisense oligonucleotides.
Author: Ross, P J|George, M|Cunningham, D|DiStefano, F|Andreyev, H J|Workman, P|Clarke, P A
PMID: 12467236
Journal: Carcinogenesis. 2002 Jan;23(1):201-5.
Title: AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis.
Author: Roy, Hemant K|Olusola, Bola F|Clemens, Dahn L|Karolski, William J|Ratashak, Anne|Lynch, Henry T|Smyrk, Thomas C
PMID: 11756242
Journal: Oncogene. 2002 Jan 3;21(1):78-86.
Title: Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Author: Venkateswarlu, Srinivas|Dawson, Dawn M|St Clair, Patricia|Gupta, Anjana|Willson, James K V|Brattain, Michael G
PMID: 11791178
Journal: Oncogene. 2002 Jan 17;21(3):337-46.
Title: Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author: Nam, Seon Young|Amoscato, Andrew A|Lee, Yong J
PMID: 11821946
Journal: Int J Cancer. 2002 Apr 10;98(5):665-73.
Title: Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation.
Author: Ewton, Daina Z|Kansra, Sanjay|Lim, Seunghwan|Friedman, Eileen
PMID: 11920634
Journal: Cell Death Differ. 2002 Jul;9(7):768-79.
Title: Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.
Author: Garrouste, F|Remacle-Bonnet, M|Fauriat, C|Marvaldi, J|Luis, J|Pommier, G
PMID: 12058282
Journal: Clin Cancer Res. 2002 Jun;8(6):1957-63.
Title: The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY294002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells.
Author: Semba, Shuho|Itoh, Nanami|Ito, Masafumi|Harada, Masaru|Yamakawa, Mitsunori
PMID: 12060641
Journal: Cancer Res. 2002 Jun 15;62(12):3402-7.
Title: A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.
Author: Casanova, M Llanos|Larcher, Fernando|Casanova, Benito|Murillas, Rodolfo|Fernandez-Acenero, M Jesus|Villanueva, Concepcion|Martinez-Palacio, Jesus|Ullrich, Axel|Conti, Claudio J|Jorcano, Jose Luis
PMID: 12067982
Journal: Cancer. 2002 Jun 15;94(12):3127-34.
Title: Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma.
Author: Itoh, Nanami|Semba, Shuho|Ito, Masafumi|Takeda, Hiroaki|Kawata, Sumio|Yamakawa, Mitsunori
PMID: 12115344
Journal: J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24.
Title: Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
Author: Wang, Qingding|Wang, Xiaofu|Hernandez, Ambrosio|Hellmich, Mark R|Gatalica, Zoran|Evers, B Mark
PMID: 12140294
Journal: J Biol Chem. 2002 Oct 11;277(41):38013-20. Epub 2002 Jul 26.
Title: Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway.
Author: Ghatak, Shibnath|Misra, Suniti|Toole, Bryan P
PMID: 12145277
Journal: Am J Pathol. 2002 Aug;161(2):439-47.
Title: PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers.
Author: Zhou, Xiao-Ping|Loukola, Anu|Salovaara, Reijo|Nystrom-Lahti, Minna|Peltomaki, Paivi|de la Chapelle, Albert|Aaltonen, Lauri A|Eng, Charis
PMID: 12163369
Journal: J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19.
Title: Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma.
Author: Hsi, Linda C|Wilson, Leigh C|Eling, Thomas E
PMID: 12189136
Journal: Pharmacol Ther. 2002 Feb-Mar;93(2-3):233-42.
Title: Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties.
Author: Yoganathan, N|Yee, A|Zhang, Z|Leung, D|Yan, J|Fazli, L|Kojic, D L|Costello, P C|Jabali, M|Dedhar, S|Sanghera, J
PMID: 12191615
Journal: FASEB J. 2002 Oct;16(12):1642-4.
Title: Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice.
Author: Guerrero, Silvia|Figueras, Agnes|Casanova, Isolda|Farre, Lourdes|Lloveras, Belen|Capella, Gabriel|Trias, Manuel|Mangues, Ramon
PMID: 12207005
Journal: Gastroenterology. 2002 Oct;123(4):1191-204.
Title: Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines.
Author: Adachi, Yasushi|Lee, Choon-Taek|Coffee, Keith|Yamagata, Noboru|Ohm, Joyce E|Park, Kyung-Ho|Dikov, Mikhail M|Nadaf, Sorena R|Arteaga, Carlos L|Carbone, David P
PMID: 12360481
Journal: Clin Cancer Res. 2002 Oct;8(10):3250-8.
Title: Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa).
Author: Bianco, Cataldo|Tortora, Giampaolo|Bianco, Roberto|Caputo, Roberta|Veneziani, Bianca Maria|Caputo, Rosa|Damiano, Vincenzo|Troiani, Teresa|Fontanini, Gabriella|Raben, David|Pepe, Stefano|Bianco, A Raffaele|Ciardiello, Fortunato
PMID: 12374696
Journal: Oncogene. 2002 Nov 7;21(51):7797-807.
Title: Src activation regulates anoikis in human colon tumor cell lines.
Author: Windham, T Christopher|Parikh, Nila U|Siwak, Doris R|Summy, Justin M|McConkey, David J|Kraker, Alan J|Gallick, Gary E
PMID: 12420216
Journal: Br Med Bull. 2002;64:227-54.
Title: Therapeutics targeting signal transduction for patients with colorectal carcinoma.
Author: de Bono, Johann S|Rowinsky, Eric K
PMID: 12421735
Journal: Clin Cancer Res. 2002 Dec;8(12):3824-31.
Title: Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma.
Author: Semba, Shuho|Itoh, Nanami|Ito, Masafumi|Youssef, Emile M|Harada, Masaru|Moriya, Toshiyuki|Kimura, Wataru|Yamakawa, Mitsunori
PMID: 12473596
Journal: J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):213-28.
Title: Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate.
Author: Schnyder, Bruno|Lahm, Harald|Pittet, Martine|Schnyder-Candrian, Silvia
PMID: 12503617
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G996-1005. Epub 2003 Feb
Title: Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line.
Author: Cho, Han J|Kim, Woo K|Kim, Eun J|Jung, Kyeong C|Park, Soochul|Lee, Hyun S|Tyner, Angela L|Park, Jung H Y
PMID: 12571082
Journal: Int J Cancer. 2003 May 10;104(6):722-7.
Title: Differential effects between amphoterin and advanced glycation end products on colon cancer cells.
Author: Kuniyasu, Hiroki|Chihara, Yoshitomo|Kondo, Hideaki
PMID: 12640679
Journal: Cancer Res. 2003 May 1;63(9):2330-4.
Title: Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.
Author: Fukuda, Ryo|Kelly, Brian|Semenza, Gregg L
PMID: 12727858
Journal: Mol Pharmacol. 2003 Jun;63(6):1281-8.
Title: Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist.
Author: Burbridge, Mike F|Venot, Virginie|Casara, Patrick J|Perron-Sierra, Francoise|Hickman, John A|Tucker, Gordon C
PMID: 12761337
Journal: Semin Oncol. 2003 Jun;30(3 Suppl 6):56-67.
Title: Signaling inhibition with radiation in colorectal cancer: clinical trials.
Author: McKenna, W Gillies|Muschel, Ruth J|Gupta, Anjali|Hahn, Stephen|Bernhard, Eric J
PMID: 12802796
Journal: J Biol Chem. 2003 Sep 12;278(37):35451-7. Epub 2003 Jun 24.
Title: Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor.
Author: Buchanan, F Gregory|Wang, Dingzhi|Bargiacchi, Francesca|DuBois, Raymond N
PMID: 12824187
Journal: Cancer Res. 2003 Jul 1;63(13):3632-6.
Title: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.
Author: Liu, Wenbiao|Reinmuth, Niels|Stoeltzing, Oliver|Parikh, Alexander A|Tellez, Carmen|Williams, Simon|Jung, Young D|Fan, Fan|Takeda, Akihiko|Akagi, Morihisa|Bar-Eli, Menashe|Gallick, Gary E|Ellis, Lee M
PMID: 12839952
Journal: Int J Oncol. 2003 Aug;23(2):503-8.
Title: Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.
Author: Lee, Eun Ju|Park, Hye Geong|Kang, Ho Sung
PMID: 12851702
Journal: Clin Cancer Res. 2003 Jul;9(7):2457-64.
Title: A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.
Author: Daneshmand, Manijeh|Parolin, Doris A E|Hirte, Holger W|Major, Pierre|Goss, Glenwood|Stewart, David|Batist, Gerald|Miller, Wilson H Jr|Matthews, Sarah|Seymour, Lesley|Lorimer, Ian A J
PMID: 12855618
Journal: J Nutr. 2003 Aug;133(8):2675-81.
Title: Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Author: Kim, Eun Ji|Kang, Il-Jun|Cho, Han Jin|Kim, Woo Kyoung|Ha, Yeong-Lae|Park, Jung Han Yoon
PMID: 12888657
Journal: Mol Cancer Res. 2003 Aug;1(10):755-64.
Title: Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
Author: Golubovskaya, Vita M|Gross, Steven|Kaur, Aparna S|Wilson, Richard I|Xu, Li-Hui|Yang, Xi Hui|Cance, William G
PMID: 12939401
Journal: Int J Mol Med. 2003 Oct;12(4):633-41.
Title: Induction of macrophage migration inhibitory factor by lysophosphatidic acid: relevance to tumor growth and angiogenesis.
Author: Sun, Bailong|Nishihira, Jun|Suzuki, Masaki|Fukushima, Nobuyuki|Ishibashi, Teruo|Kondo, Masao|Sato, Yuji|Todo, Satoru
PMID: 12964047
Journal: Gut. 2003 Oct;52(10):1472-8.
Title: Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells.
Author: Sheng, H|Shao, J|Townsend, C M Jr|Evers, B M
PMID: 12970141
Journal: Clin Cancer Res. 2003 Oct 15;9(13):4802-10.
Title: Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis.
Author: Kuniyasu, Hiroki|Ohmori, Hitoshi|Sasaki, Takamistu|Sasahira, Tomonori|Yoshida, Kazuhiro|Kitadai, Yasuhiko|Fidler, Isaiah J
PMID: 14581351
Journal: Cancer Res. 2003 Oct 15;63(20):6726-34.
Title: Inhibition of angiotensin II activity enhanced the antitumor effect of cyclooxygenase-2 inhibitors via insulin-like growth factor I receptor pathway.
Author: Yasumaru, Masakazu|Tsuji, Shingo|Tsujii, Masahiko|Irie, Takanobu|Komori, Masato|Kimura, Arata|Nishida, Tsutomu|Kakiuchi, Yoshimi|Kawai, Naoki|Murata, Hiroaki|Horimoto, Masayoshi|Sasaki, Yutaka|Hayashi, Norio|Kawano, Sunao|Hori, Masatsugu
PMID: 14583467
Journal: Cancer Gene Ther. 2003 Nov;10(11):803-13.
Title: Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells.
Author: Saito, Yuji|Gopalan, Began|Mhashilkar, Abner M|Roth, Jack A|Chada, Sunil|Zumstein, Louis|Ramesh, Rajagopal
PMID: 14605666
Journal: Nat Genet. 2003 Dec;35(4):323-30. Epub 2003 Nov 16.
Title: Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Author: Aoki, Koji|Tamai, Yoshitaka|Horiike, Shigeo|Oshima, Masanobu|Taketo, Makoto M
PMID: 14625550
Journal: Cancer Res. 2003 Nov 15;63(22):7708-16.
Title: Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway.
Author: Sekharam, Madhavi|Zhao, Haiyan|Sun, Mei|Fang, Quan|Zhang, Qingbo|Yuan, Zengqiang|Dan, Han C|Boulware, David|Cheng, Jin Q|Coppola, Domenico
PMID: 14633695
Journal: Eur J Cancer Prev. 2003 Dec;12(6):469-78.
Title: The in vitro effects of H-89, a specific inhibitor of protein kinase A, in the human colonic carcinoma cell line Caco-2.
Author: Bockmann, S|Nebe, B
PMID: 14639124
Journal: Cancer Res. 2003 Dec 15;63(24):8600-5.
Title: Additive interaction of oxaliplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines results from inhibition of nuclear factor kappaB signaling.
Author: Rakitina, Tatiana V|Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 14695170
Journal: Horm Metab Res. 2003 Nov-Dec;35(11-12):850-6.
Title: Inhibition of the biologic response to insulin-like growth factor I in MCF-7 breast cancer cells by a new monoclonal antibody to the insulin-like growth factor-I receptor. The importance of receptor down-regulation.
Author: Jackson-Booth, P-G|Terry, C|Lackey, B|Lopaczynska, M|Nissley, P
PMID: 14710368
Journal: Carcinogenesis. 2004 Feb;25(2):241-8.
Title: Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma.
Author: Khaleghpour, Kianoush|Li, Yang|Banville, Denis|Yu, Zhenbao|Shen, Shi-Hsiang
PMID: 14578160
Journal: FASEB J. 2004 Jan;18(1):140-2. Epub 2003 Nov 20.
Title: Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion.
Author: Nubel, Tobias|Dippold, Wolfgang|Kleinert, Hartmut|Kaina, Bernd|Fritz, Gerhard
PMID: 14630701
Journal: Oncogene. 2004 Apr 1;23(14):2465-71.
Title: An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B.
Author: Fishman, Pnina|Bar-Yehuda, Sara|Ohana, Gil|Barer, Faina|Ochaion, Avivit|Erlanger, Abigail|Madi, Lea
PMID: 14691449
Journal: Oncogene. 2004 Jan 15;23(2):617-28.
Title: PTEN mutations are common in sporadic microsatellite stable colorectal cancer.
Author: Nassif, Najah T|Lobo, Glenn P|Wu, Xiaojuan|Henderson, Christopher J A|Morrison, Carl D|Eng, Charis|Jalaludin, Bin|Segelov, Eva
PMID: 14724591
Journal: Cancer Res. 2004 Jan 15;64(2):665-71.
Title: Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.
Author: Miyamoto, Shin'ichi|Yano, Keiichi|Sugimoto, Seiji|Ishii, Genichiro|Hasebe, Takahiro|Endoh, Yasushi|Kodama, Keiji|Goya, Masato|Chiba, Tsutomu|Ochiai, Atsushi
PMID: 14744783
Journal: Clin Cancer Res. 2004 Jan 15;10(2):784-93.
Title: Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.
Author: Ciardiello, Fortunato|Bianco, Roberto|Caputo, Roberta|Caputo, Rosa|Damiano, Vincenzo|Troiani, Teresa|Melisi, Davide|De Vita, Ferdinando|De Placido, Sabino|Bianco, A Raffaele|Tortora, Giampaolo
PMID: 14760102
Journal: Am J Pathol. 2004 Mar;164(3):987-95.
Title: ARK5 expression in colorectal cancer and its implications for tumor progression.
Author: Kusakai, Gen-ichi|Suzuki, Atsushi|Ogura, Tsutomu|Miyamoto, Sin'ichi|Ochiai, Atsushi|Kaminishi, Michio|Esumi, Hiroyasu
PMID: 14982852
Journal: Cancer Res. 2004 Apr 1;64(7):2601-9.
Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
Author: Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G
PMID: 15059917
Journal: Cancer Cell. 2004 Apr;5(4):329-39.
Title: Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway.
Author: Bao, Shideng|Ouyang, Gaoliang|Bai, Xuefang|Huang, Zhi|Ma, Chaoyu|Liu, Ming|Shao, Rong|Anderson, Ryan M|Rich, Jeremy N|Wang, Xiao-Fan
PMID: 15093540
Journal: Clin Cancer Res. 2004 May 15;10(10):3448-56.
Title: Pak-1 expression increases with progression of colorectal carcinomas to metastasis.
Author: Carter, Julia H|Douglass, Larry E|Deddens, James A|Colligan, Bruce M|Bhatt, Tejal R|Pemberton, Jackson O|Konicek, Susan|Hom, Joanne|Marshall, Mark|Graff, Jeremy R
PMID: 15161701
Journal: Cancer Res. 2004 Jun 1;64(11):4018-23.
Title: Cripto: a novel target for antibody-based cancer immunotherapy.
Author: Xing, Pei Xiang|Hu, Xiu Feng|Pietersz, Geoffrey A|Hosick, Howard L|McKenzie, Ian F C
PMID: 15173016
Journal: Semin Oncol. 2004 Apr;31(2 Suppl 7):36-44.
Title: COX-2 inhibitors and other nonsteroidal anti-inflammatory drugs in genitourinary cancer.
Author: Sabichi, Anita L|Lippman, Scott M
PMID: 15179622
Journal: Cancer Lett. 2004 Jul 16;210(2):139-50.
Title: Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma.
Author: Khor, Tin Oo|Gul, Yunus A|Ithnin, Hairuszah|Seow, Heng Fong
PMID: 15183529
Journal: Mol Cancer Ther. 2004 Jun;3(6):755-62.
Title: Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.
Author: Mallon, Robert|Feldberg, Larry|Kim, Steven|Collins, Karen|Wojciechowicz, Donald|Kohler, Constance|Kovacs, Diana|Discafani, Carolyn|Zhang, Nan|Wu, Biqi|Floyd, Brawner|Powell, Dennis|Berger, Dan
PMID: 15210862
Journal: Exp Mol Pathol. 2004 Aug;77(1):18-25.
Title: CD44 promotes resistance to apoptosis in human colon cancer cells.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Rubenthiran, Umayal|Jothy, Serge
PMID: 15215046
Journal: Mol Cancer Ther. 2004 Jul;3(7):763-72.
Title: Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling.
Author: Ihle, Nathan T|Williams, Ryan|Chow, Sherry|Chew, Wade|Berggren, Margareta I|Paine-Murrieta, Gillian|Minion, Daniel J|Halter, Robert J|Wipf, Peter|Abraham, Robert|Kirkpatrick, Lynn|Powis, Garth
PMID: 15252137
Journal: Oncogene. 2004 Sep 16;23(42):7067-75.
Title: Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
Author: Suzuki, Atsushi|Kusakai, Gen-Ichi|Kishimoto, Atsuhiro|Shimojo, Yosuke|Miyamoto, Sinichi|Ogura, Tsutomu|Ochiai, Atsushi|Esumi, Hiroyasu
PMID: 15273717
Journal: Steroids. 2004 Aug;69(8-9):517-22.
Title: Rapid signalling pathway activation by androgens in epithelial and stromal cells.
Author: Castoria, Gabriella|Lombardi, Maria|Barone, Maria Vittoria|Bilancio, Antonio|Di Domenico, Marina|De Falco, Antonietta|Varricchio, Lilian|Bottero, Daniela|Nanayakkara, Merlin|Migliaccio, Antimo|Auricchio, Ferdinando
PMID: 15288763
Journal: J Biol Chem. 2004 Oct 8;279(41):43261-72. Epub 2004 Aug 4.
Title: Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Author: Moran, Amy E|Hunt, Daniel H|Javid, Sara H|Redston, Mark|Carothers, Adelaide M|Bertagnolli, Monica M
PMID: 15294912
Journal: Cancer Sci. 2004 Aug;95(8):685-90.
Title: Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-qu inolinium pamoate salt, showing preferential cytotoxicity during glucose starvation.
Author: Esumi, Hiroyasu|Lu, Jie|Kurashima, Yukiko|Hanaoka, Tomoyuki
PMID: 15298733
Journal: Surgery. 2004 Aug;136(2):143-9.
Title: Inhibition of alpha5 integrin decreases PI3K activation and cell adhesion of human colon cancers.
Author: Murillo, Carlos A|Rychahou, Piotr G|Evers, B Mark
PMID: 15300173
Journal: J Biol Chem. 2004 Oct 29;279(44):45721-7. Epub 2004 Aug 18.
Title: MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress.
Author: Yin, Li|Huang, Lei|Kufe, Donald
PMID: 15322085
Journal: Front Biosci. 2004 Sep 1;9:2697-713.
Title: Prevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applications.
Author: Chu, Arthur J|Chou, Ta-Hsu|Chen, Ben D
PMID: 15353307
Journal: J Exp Clin Cancer Res. 2004 Jun;23(2):263-8.
Title: Strong association of ARK5 with tumor invasion and metastasis.
Author: Kusakai, G|Suzuki, A|Ogura, T|Kaminishi, M|Esumi, H
PMID: 15354411
Journal: Int J Oncol. 2004 Oct;25(4):1013-20.
Title: CRIPTO-1: a novel target for therapeutic intervention in human carcinoma.
Author: Normanno, Nicola|De Luca, Antonella|Maiello, Monica R|Bianco, Caterina|Mancino, Mario|Strizzi, Luigi|Arra, Claudio|Ciardiello, Fortunato|Agrawal, Sudhir|Salomon, David S
PMID: 15375551
Journal: J Biol Chem. 2004 Nov 26;279(48):49617-23. Epub 2004 Sep 17.
Title: Identification of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) as a novel downstream target of phosphatidylinositol 3-kinase/AKT/GSK-3beta pathway.
Author: Yamaguchi, Kiyoshi|Lee, Seong-Ho|Eling, Thomas E|Baek, Seung Joon
PMID: 15377673
Journal: Curr Drug Targets Immune Endocr Metabol Disord. 2004 Sep;4(3):181-5.
Title: Akt: a potential target for thyroid cancer therapy.
Author: Kada, Faiza|Saji, Motoyasu|Ringel, Matthew D
PMID: 15379721
Journal: Cancer Cell. 2004 Sep;6(3):285-95.
Title: Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta.
Author: Wang, Dingzhi|Wang, Haibin|Shi, Qiong|Katkuri, Sharada|Walhi, Walter|Desvergne, Beatrice|Das, Sanjoy K|Dey, Sudhansu K|DuBois, Raymond N
PMID: 15380519
Journal: Int J Oncol. 2004 Nov;25(5):1459-64.
Title: Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells.
Author: Sovova, Vlasta|Kucerova, Dana|Vojtechova, Martina|Sloncova, Eva|Tuhackova, Zdena
PMID: 15492839
Journal: Oncogene. 2004 Dec 16;23(58):9369-80.
Title: Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation.
Author: Singh, Anurag|Karnoub, Antoine E|Palmby, Todd R|Lengyel, Ernst|Sondek, John|Der, Channing J
PMID: 15516977
Journal: Anticancer Res. 2004 Sep-Oct;24(5A):2885-91.
Title: EGF-receptor related protein causes cell cycle arrest and induces apoptosis of colon cancer cells in vitro and in vivo.
Author: Levi, Edi|Mohammad, Ramzi|Kodali, Udayini|Marciniak, Dorota|Reddy, Sudha|Aboukameel, Amro|Sarkar, Fazlul H|Kucuk, Omer|Rishi, Arun K|Majumdar, Adhip P N
PMID: 15517892
Journal: Cancer Res. 2004 Nov 1;64(21):7655-60.
Title: PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer.
Author: Bandyopadhyay, Sucharita|Pai, Sudha K|Hirota, Shigeru|Hosobe, Sadahiro|Tsukada, Taisei|Miura, Kunio|Takano, Yukio|Saito, Ken|Commes, Therese|Piquemal, David|Watabe, Misako|Gross, Steven|Wang, Ying|Huggenvik, Jodi|Watabe, Kounosuke
PMID: 15520163
Journal: Cell Prolif. 2004 Dec;37(6):427-41.
Title: Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals.
Author: Walsh, M F|Woo, R K-Y|Gomez, R|Basson, M D
PMID: 15548175
Journal: Oncol Res. 2004;14(10):513-27.
Title: In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316.
Author: Meuillet, Emmanuelle J|Ihle, Nathan|Baker, Amanda F|Gard, Jaime M|Stamper, Chelsea|Williams, Ryan|Coon, Amy|Mahadevan, Daruka|George, Benjamin L|Kirkpatrick, Lynn|Powis, Garth
PMID: 15559765
Journal: Clin Cancer Res. 2004 Nov 15;10(22):7727-37.
Title: Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model.
Author: Narayanan, Bhagavathi A|Narayanan, Narayanan K|Pittman, Brian|Reddy, Bandaru S
PMID: 15570007
Journal: Postepy Hig Med Dosw (Online). 2004;58:428-37.
Title: [Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines].
Author: Pajak, Beata|Orzechowski, Arkadiusz
PMID: 15577750
Journal: Mol Cancer Ther. 2004 Dec;3(12):1615-21.
Title: Epidermal growth factor receptor-related peptide inhibits growth of PC-3 prostate cancer cells.
Author: Marciniak, Dorota J|Rishi, Arun K|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 15634655
Journal: Oncogene. 2005 Jan 6;24(1):148-56.
Title: The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein.
Author: Bhonde, Mandar R|Hanski, Marie-Luise|Magrini, Roberta|Moorthy, Dhatchana|Muller, Antje|Sausville, Edward A|Kohno, Kimitoshi|Wiegand, Peter|Daniel, Peter T|Zeitz, Martin|Hanski, Christoph
PMID: 15467762
Journal: Oncogene. 2005 Feb 17;24(8):1338-47.
Title: Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.
Author: Ravid, Dana|Maor, Sharon|Werner, Haim|Liscovitch, Mordechai
PMID: 15592498
Journal: Oncogene. 2005 Feb 3;24(6):1021-31.
Title: The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.
Author: Agarwal, Anju|Das, Kingshuk|Lerner, Natalia|Sathe, Swati|Cicek, Muzaffer|Casey, Graham|Sizemore, Nywana
PMID: 15592509
Journal: J Cell Physiol. 2005 Jul;204(1):36-44.
Title: Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor.
Author: Sainaghi, Pier Paolo|Castello, Luigi|Bergamasco, Luca|Galletti, Margherita|Bellosta, Paola|Avanzi, Gian Carlo
PMID: 15605394
Journal: Cell Cycle. 2005 Mar;4(3):456-64.
Title: Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells.
Author: Caron, Ruben W|Yacoub, Adly|Mitchell, Clint|Zhu, Xiaoyu|Hong, Young|Sasazuki, Takehiko|Shirasawa, Senji|Hagan, Michael P|Grant, Steven|Dent, Paul
PMID: 15655348
Journal: Br J Pharmacol. 2005 Feb;144(3):338-48.
Title: Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E2 production.
Author: Colucci, Rocchina|Blandizzi, Corrado|Tanini, Marzia|Vassalle, Cristina|Breschi, Maria Cristina|Del Tacca, Mario
PMID: 15655524
Journal: J Biol Chem. 2005 Apr 8;280(14):13538-44.
Title: The pro-inflammatory mediator leukotriene D4 induces phosphatidylinositol 3-kinase and Rac-dependent migration of intestinal epithelial cells.
Author: Paruchuri, Sailaja|Broom, Oliver|Dib, Karim|Sjolander, Anita
PMID: 15657050
Journal: Cell Physiol Biochem. 2005;15(1-4):29-40.
Title: TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
Author: Ahn, Dae-ho|Crawley, Suzanne C|Hokari, Ryota|Kato, Shingo|Yang, Stacey C|Li, Jian-Dong|Kim, Young S
PMID: 15665513
Journal: Carcinogenesis. 2005 May;26(5):900-7.
Title: The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells.
Author: Wollmann, Wyatt|Goodman, Mike L|Bhat-Nakshatri, Poornima|Kishimoto, Hiromitsu|Goulet, Robert J Jr|Mehrotra, Sanjana|Morimiya, Akira|Badve, Sunil|Nakshatri, Harikrishna
PMID: 15677629
Journal: Oncogene. 2005 Mar 3;24(10):1788-93.
Title: Low daunomycin concentrations protect colorectal cancer cells from hypoxia-induced apoptosis.
Author: Lechanteur, Chantal|Jacobs, Nathalie|Greimers, Roland|Benoit, Valerie|Deregowski, Valerie|Chariot, Alain|Merville, Marie-Paule|Bours, Vincent
PMID: 15688011
Journal: Mol Cancer Ther. 2005 Feb;4(2):243-55.
Title: H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Author: Caron, Ruben W|Yacoub, Adly|Zhu, Xiaoyu|Mitchell, Clint|Han, Song Iy|Sasazuki, Takehiko|Shirasawa, Senji|Hagan, Michael P|Grant, Steven|Dent, Paul
PMID: 15713896
Journal: Neoplasia. 2005 Jan;7(1):85-90.
Title: CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model.
Author: Bar-Yehuda, Sara|Madi, Lea|Silberman, Daniel|Gery, Slosman|Shkapenuk, Maya|Fishman, Pnina
PMID: 15720820
Journal: Am J Physiol Cell Physiol. 2005 Jul;289(1):C2-11. Epub 2005 Feb 23.
Title: LPA2 receptor mediates mitogenic signals in human colon cancer cells.
Author: Yun, C Chris|Sun, Hong|Wang, Dongsheng|Rusovici, Raluca|Castleberry, Amanda|Hall, Randy A|Shim, Hyunsuk
PMID: 15728708
Journal: J Nutr Biochem. 2005 Mar;16(3):155-62.
Title: Quercetin decreases the expression of ErbB2 and ErbB3 proteins in HT-29 human colon cancer cells.
Author: Kim, Woo K|Bang, Myung H|Kim, Eul S|Kang, Nam E|Jung, Kyeong C|Cho, Han J|Park, Jung H Y
PMID: 15741050
Journal: Nutr Cancer. 2005;51(1):110-6.
Title: Ursodeoxycholic acid can suppress deoxycholic acid-induced apoptosis by stimulating Akt/PKB-dependent survival signaling.
Author: Im, Eunok|Akare, Sandeep|Powell, Ashley|Martinez, Jesse D
PMID: 15749637
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: Clin Cancer Res. 2005 Mar 15;11(6):2398-407.
Title: Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor.
Author: Mantha, Angela J|Hanson, Jennifer E L|Goss, Glenwood|Lagarde, Alain E|Lorimer, Ian A|Dimitroulakos, Jim
PMID: 15788691
Journal: Mol Cell. 2005 Apr 1;18(1):13-24.
Title: PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.
Author: Gao, Tianyan|Furnari, Frank|Newton, Alexandra C
PMID: 15808505
Journal: Clin Cancer Res. 2005 Apr 1;11(7):2735-46.
Title: (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
Author: Shimizu, Masahito|Deguchi, Atsuko|Lim, Jin T E|Moriwaki, Hisataka|Kopelovich, Levy|Weinstein, I Bernard
PMID: 15814656
Journal: Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37.
Title: Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Author: Smith, Victoria|Sausville, Edward A|Camalier, Richard F|Fiebig, Heinz-Herbert|Burger, Angelika M
PMID: 15841378
Journal: Anticancer Drugs. 2005 Jun;16(5):533-41.
Title: The patellazoles inhibit protein synthesis at nanomolar concentrations in human colon tumor cells.
Author: Richardson, Adam D|Aalbersberg, William|Ireland, Chris M
PMID: 15846119
Journal: Cancer Res. 2005 May 1;65(9):3716-25.
Title: Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
Author: Yokoi, Kenji|Thaker, Premal H|Yazici, Sertac|Rebhun, Robert R|Nam, Do-Hyun|He, Junqin|Kim, Sun-Jin|Abbruzzese, James L|Hamilton, Stanley R|Fidler, Isaiah J
PMID: 15867367
Journal: Cancer Res. 2005 May 1;65(9):3853-60.
Title: Supra-additive growth inhibition by a celecoxib analogue and carboxyamido-triazole is primarily mediated through apoptosis.
Author: Winters, Mary E|Mehta, Arpita I|Petricoin, Emanuel F 3rd|Kohn, Elise C|Liotta, Lance A
PMID: 15867384
Journal: Carcinogenesis. 2005 Sep;26(9):1503-12. Epub 2005 May 11.
Title: Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells.
Author: Dihlmann, Susanne|Kloor, Matthias|Fallsehr, Christine|von Knebel Doeberitz, Magnus
PMID: 15888491
Journal: Cancer Res. 2005 May 15;65(10):4253-60.
Title: HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
Author: Hirata, Akira|Hosoi, Fumihito|Miyagawa, Miho|Ueda, Shu-ichi|Naito, Seiji|Fujii, Teruhiko|Kuwano, Michihiko|Ono, Mayumi
PMID: 15899817
Journal: Mol Pharmacol. 2005 Aug;68(2):477-86.
Title: Characterization of a human carcinoma cell line selected for resistance to the farnesyl transferase inhibitor 4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyri din-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxami
Author: Bruzek, Laura M|Poynter, Jenny N|Kaufmann, Scott H|Adjei, Alex A
PMID: 15901852
Journal: Mol Pharmacol. 2005 Aug;68(2):502-10. Epub 2005 May 20.
Title: Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.
Author: Janmaat, Maarten L|Rodriguez, Jose A|Jimeno, Jose|Kruyt, Frank A E|Giaccone, Giuseppe
PMID: 15908515
Journal: Gut. 2005 Oct;54(10):1437-44.
Title: Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer.
Author: Sekikawa, A|Fukui, H|Fujii, S|Nanakin, A|Kanda, N|Uenoyama, Y|Sawabu, T|Hisatsune, H|Kusaka, T|Ueno, S|Nakase, H|Seno, H|Fujimori, T|Chiba, T
PMID: 15914572
Journal: Exp Cell Res. 2005 Jul 1;307(1):231-46. Epub 2005 Apr 19.
Title: Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
Author: Halder, Sunil K|Beauchamp, R Daniel|Datta, Pran K
PMID: 15922743
Journal: Cancer Res. 2005 Jun 1;65(11):4562-7.
Title: Functional analysis of PIK3CA gene mutations in human colorectal cancer.
Author: Ikenoue, Tsuneo|Kanai, Fumihiko|Hikiba, Yohko|Obata, Toshiyuki|Tanaka, Yasuo|Imamura, Jun|Ohta, Miki|Jazag, Amarsanaa|Guleng, Bayasi|Tateishi, Keisuke|Asaoka, Yoshinari|Matsumura, Masayuki|Kawabe, Takao|Omata, Masao
PMID: 15930273
Journal: Cancer Cell. 2005 Jun;7(6):561-73.
Title: Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
Author: Samuels, Yardena|Diaz, Luis A Jr|Schmidt-Kittler, Oleg|Cummins, Jordan M|Delong, Laura|Cheong, Ian|Rago, Carlo|Huso, David L|Lengauer, Christoph|Kinzler, Kenneth W|Vogelstein, Bert|Velculescu, Victor E
PMID: 15950905
Journal: Clin Cancer Res. 2005 Jun 15;11(12):4338-40.
Title: Stability of phosphoprotein as a biological marker of tumor signaling.
Author: Baker, Amanda F|Dragovich, Tomislav|Ihle, Nathan T|Williams, Ryan|Fenoglio-Preiser, Cecilia|Powis, Garth
PMID: 15958615
Journal: Cancer Biol Ther. 2005 Jul;4(7):709-15. Epub 2005 Jul 28.
Title: AKT activation and response to interferon-beta in human cancer cells.
Author: Lei, Hanqin|Furlong, Patrick J|Ra, Jin Hee|Mullins, Daniel|Cantor, Robert|Fraker, Douglas L|Spitz, Francis R
PMID: 15970687
Journal: Biochem Pharmacol. 2005 Aug 15;70(4):580-9.
Title: 17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
Author: Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 15993848
Journal: Oncogene. 2005 Oct 20;24(46):6936-44.
Title: ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Author: Suzuki, Atsushi|Iida, Shinsuke|Kato-Uranishi, Miyuki|Tajima, Emi|Zhan, Fenghuang|Hanamura, Ichiro|Huang, Yongsheng|Ogura, Tsutomu|Takahashi, Satoru|Ueda, Ryuzo|Barlogie, Bart|Shaughnessy, John Jr|Esumi, Hiroyasu
PMID: 16044163
Journal: J Cell Biochem. 2005 Sep 1;96(1):155-69.
Title: Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells.
Author: Liao, Chiung-Ho|Sang, Shengmin|Ho, Chi-Tang|Lin, Jen-Kun
PMID: 16052481
Journal: Cancer Res. 2005 Aug 15;65(16):7462-9.
Title: The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts.
Author: Graff, Jeremy R|McNulty, Ann M|Hanna, Kimberly Ross|Konicek, Bruce W|Lynch, Rebecca L|Bailey, Spring N|Banks, Crystal|Capen, Andrew|Goode, Robin|Lewis, Jason E|Sams, Lillian|Huss, Karen L|Campbell, Robert M|Iversen, Philip W|Neubauer, Blake Lee|Brown, Tho
PMID: 16103100
Journal: Exp Cell Res. 2005 Oct 15;310(1):117-30.
Title: CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation.
Author: Brand, Stephan|Dambacher, Julia|Beigel, Florian|Olszak, Torsten|Diebold, Joachim|Otte, Jan-Michel|Goke, Burkhard|Eichhorst, Soren T
PMID: 16125170
Journal: Am J Pathol. 2005 Sep;167(3):761-73.
Title: Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily.
Author: Remacle-Bonnet, Maryse|Garrouste, Francoise|Baillat, Gilbert|Andre, Frederic|Marvaldi, Jacques|Pommier, Gilbert
PMID: 16127155
Journal: World J Gastroenterol. 2005 Sep 7;11(33):5142-50.
Title: Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells.
Author: Cho, Han Jin|Kim, Woo Kyoung|Jung, Jae In|Kim, Eun Ji|Lim, Soon Sung|Kwon, Dae Young|Park, Jung Han Yoon
PMID: 16127743
Journal: Cancer Sci. 2005 Sep;96(9):620-6.
Title: Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs.
Author: Yanagihara, Miyako|Katano, Masayoshi|Takahashi-Sasaki, Noriko|Kimata, Kiyonori|Taira, Kazunari|Andoh, Toshiwo
PMID: 16128748
Journal: Surgery. 2005 Aug;138(2):382-90.
Title: Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation.
Author: Chen, Andy L|Soman, Kizhake V|Rychahou, Piotr G|Luxon, Bruce A|Evers, B Mark
PMID: 16153451
Journal: Surgery. 2005 Aug;138(2):391-7.
Title: Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).
Author: Rychahou, Piotr G|Murillo, Carlos A|Evers, B Mark
PMID: 16153452
Journal: Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
Title: Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Author: Ogino, Shuji|Meyerhardt, Jeffrey A|Cantor, Mami|Brahmandam, Mohan|Clark, Jeffrey W|Namgyal, Chungdak|Kawasaki, Takako|Kinsella, Kate|Michelini, Ann L|Enzinger, Peter C|Kulke, Matthew H|Ryan, David P|Loda, Massimo|Fuchs, Charles S
PMID: 16166444
Journal: Breast Cancer Res. 2005;7(5):R609-16.
Title: Somatic mutation and gain of copy number of PIK3CA in human breast cancer.
Author: Wu, Guojun|Xing, Mingzhao|Mambo, Elizabeth|Huang, Xin|Liu, Junwei|Guo, Zhongmin|Chatterjee, Aditi|Goldenberg, David|Gollin, Susanne M|Sukumar, Saraswati|Trink, Barry|Sidransky, David
PMID: 16168105
Journal: J Biol Chem. 2005 Dec 9;280(49):41047-56.
Title: Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression.
Author: Kim, Ki M|Song, Jae J|An, Jee Young|Kwon, Yong Tae|Lee, Yong J
PMID: 16199534
Journal: Cancer Res. 2005 Oct 1;65(19):8604-7.
Title: Overexpressed beta-catenin blocks nitric oxide-induced apoptosis in colonic cancer cells.
Author: Wang, Hongying|MacNaughton, Wallace K
PMID: 16204024
Journal: Clin Cancer Res. 2005 Nov 1;11(21):7621-8.
Title: X-Linked inhibitor of apoptosis protein expression level in colorectal cancer is regulated by hepatocyte growth factor/C-met pathway via Akt signaling.
Author: Takeuchi, Hiroya|Kim, Joseph|Fujimoto, Akihide|Umetani, Naoyuki|Mori, Takuji|Bilchik, Anton|Turner, Rod|Tran, Andy|Kuo, Christine|Hoon, Dave S B
PMID: 16278380
Journal: Cancer Res. 2005 Nov 15;65(22):10623-31.
Title: Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.
Author: Ju, Jihyeung|Hong, Jungil|Zhou, Jian-nian|Pan, Zui|Bose, Mousumi|Liao, Jie|Yang, Guang-yu|Liu, Ying Ying|Hou, Zhe|Lin, Yong|Ma, Jianjie|Shih, Weichung Joe|Carothers, Adelaide M|Yang, Chung S
PMID: 16288056
Journal: Science. 2005 Dec 2;310(5753):1504-10.
Title: Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.
Author: Castellone, Maria Domenica|Teramoto, Hidemi|Williams, Bart O|Druey, Kirk M|Gutkind, J Silvio
PMID: 16293724
Journal: Cancer Biol Ther. 2005 Oct;4(10):1159-67. Epub 2005 Oct 23.
Title: Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Author: Caraglia, Michele|Marra, Monica|Budillon, Alfredo|Meo, Giuseppina|Ricciardiello, Filippo|Bismuto, Ettore|Brachelente, Giovanni|Francini, Guido|Giordano, Antonio|Correale, Pierpaolo|Abbruzzese, Alberto
PMID: 16294035
Journal: Cancer Biol Ther. 2005 Dec;4(12):1381-6. Epub 2005 Dec 31.
Title: Assessment of Epidermal Growth Factor Receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis.
Author: Messersmith, Wells|Oppenheimer, Darin|Peralba, Josep|Sebastiani, Valeria|Amador, Maria|Jimeno, Antonio|Embuscado, Erlinda|Hidalgo, Manuel|Iacobuzio-Donahue, Christine
PMID: 16319527
Journal: Cancer Res. 2005 Dec 15;65(24):11605-12.
Title: The shed ectodomain of Nr-CAM stimulates cell proliferation and motility, and confers cell transformation.
Author: Conacci-Sorrell, Maralice|Kaplan, Anna|Raveh, Shani|Gavert, Nancy|Sakurai, Takeshi|Ben-Ze'ev, Avri
PMID: 16357171
Journal: J Clin Oncol. 2005 Dec 20;23(36):9265-74.
Title: Randomized phase II trial of the clinical and biological effects of two dose levels of gefitinib in patients with recurrent colorectal adenocarcinoma.
Author: Rothenberg, Mace L|LaFleur, Bonnie|Levy, Donna E|Washington, Mary Kay|Morgan-Meadows, Sherry L|Ramanathan, Ramesh K|Berlin, Jordan D|Benson, Al B 3rd|Coffey, Robert J
PMID: 16361624
Journal: J Med Food. 2005 Winter;8(4):431-8.
Title: Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein.
Author: Kim, Eun Ji|Shin, Hyun-Kyung|Park, Jung Han Yoon
PMID: 16379552
Journal: J Exp Ther Oncol. 2005;5(1):69-78.
Title: EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Author: Shimizu, Masahito|Deguchi, Atsuko|Joe, Andrew K|Mckoy, Judith F|Moriwaki, Hisataka|Weinstein, I Bernard
PMID: 16416603
Journal: Cell Death Differ. 2006 Feb;13(2):189-201.
Title: Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
Author: Oehme, I|Bosser, S|Zornig, M
PMID: 16082389
Journal: Carcinogenesis. 2006 Feb;27(2):298-306.
Title: Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells.
Author: Ellington, Allison A|Berhow, Mark A|Singletary, Keith W
PMID: 16113053
Journal: J Pharmacol Exp Ther. 2006 Jan;316(1):25-34. Epub 2005 Sep 16.
Title: Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation.
Author: Hundley, Thomas R|Rigas, Basil
PMID: 16169935
Journal: Exp Mol Pathol. 2006 Apr;80(2):165-70. Epub 2005 Oct 3.
Title: Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues.
Author: Kim, Hyun-Ah|Kim, Kwang-Ho|Lee, Ryung-Ah
PMID: 16202996
Journal: J Cell Biochem. 2006 Mar 1;97(4):709-23.
Title: Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.
Author: Brand, Stephan|Olszak, Torsten|Beigel, Florian|Diebold, Joachim|Otte, Jan-Michel|Eichhorst, Soeren T|Goke, Burkhard|Dambacher, Julia
PMID: 16215992
Journal: Oncogene. 2006 Jan 5;25(1):43-50.
Title: Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase.
Author: Wang, Q|Zhou, Y|Wang, X|Evers, B M
PMID: 16278684
Journal: J Pathol. 2006 Jan;208(1):91-9.
Title: ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway.
Author: Bravou, V|Klironomos, G|Papadaki, E|Taraviras, S|Varakis, J
PMID: 16278819
Journal: Carcinogenesis. 2006 May;27(5):972-81.
Title: Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner.
Author: Lee, Seong-Ho|Yamaguchi, Kiyoshi|Kim, Jong-Sik|Eling, Thomas E|Safe, Stephen|Park, Yeonhwa|Baek, Seung Joon
PMID: 16286461
Journal: Oncogene. 2006 Mar 16;25(12):1743-52.
Title: The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1.
Author: Abdul-Ghani, R|Serra, V|Gyorffy, B|Jurchott, K|Solf, A|Dietel, M|Schafer, R
PMID: 16288223
Journal: Carcinogenesis. 2006 Mar;27(3):508-16.
Title: Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells.
Author: Kodach, Liudmila L|Bos, Carina L|Duran, Nelson|Peppelenbosch, Maikel P|Ferreira, Carmen V|Hardwick, James C H
PMID: 16344270
Journal: Int J Cancer. 2006 May 15;118(10):2381-9.
Title: Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas.
Author: Casanova, Isolda|Parreno, Matilde|Farre, Lourdes|Guerrero, Silvia|Cespedes, M Virtudes|Pavon, Miguel Angel|Sancho, Francesc J|Marcuello, Eugenio|Trias, Manuel|Mangues, Ramon
PMID: 16353145
Journal: Curr Opin Oncol. 2006 Jan;18(1):77-82.
Title: Oncogenic PI3K and its role in cancer.
Author: Samuels, Yardena|Ericson, Kajsa
PMID: 16357568
Journal: Biochem Biophys Res Commun. 2006 Feb 10;340(2):469-75. Epub 2005 Dec 15.
Title: Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines.
Author: Whyte, David B|Holbeck, Susan L
PMID: 16376301
Journal: Cancer Res. 2006 Jan 1;66(1):404-11.
Title: Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis.
Author: Zhou, Yunfei|Li, Song|Hu, Yi P|Wang, Jing|Hauser, Jennie|Conway, Alexis N|Vinci, Michelle A|Humphrey, Lisa|Zborowska, Elizabeth|Willson, James K V|Brattain, Michael G
PMID: 16397255
Journal: Gastroenterology. 2006 Jan;130(1):137-49.
Title: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
Author: Bishnupuri, Kumar S|Luo, Qizhi|Murmu, Nabendu|Houchen, Courtney W|Anant, Shrikant|Dieckgraefe, Brian K
PMID: 16401477
Journal: Carcinogenesis. 2006 May;27(5):956-61. Epub 2006 Jan 9.
Title: Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress.
Author: Derdak, Zoltan|Fulop, Peter|Sabo, Edmond|Tavares, Rose|Berthiaume, Eric P|Resnick, Murray B|Paragh, Gyorgy|Wands, Jack R|Baffy, Gyorgy
PMID: 16401637
Journal: Clin Cancer Res. 2006 Jan 15;12(2):577-83.
Title: Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.
Author: Damiano, Vincenzo|Caputo, Rosa|Bianco, Roberto|D'Armiento, Francesco P|Leonardi, Antonio|De Placido, Sabino|Bianco, A Raffaele|Agrawal, Sudhir|Ciardiello, Fortunato|Tortora, Giampaolo
PMID: 16428503
Journal: Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1492-7. Epub 2006 Jan 23.
Title: Role of beta-arrestin 1 in the metastatic progression of colorectal cancer.
Author: Buchanan, F Gregory|Gorden, D Lee|Matta, Pranathi|Shi, Qiong|Matrisian, Lynn M|DuBois, Raymond N
PMID: 16432186
Journal: Mol Cell Endocrinol. 2006 Mar 9;247(1-2):140-9. Epub 2006 Jan 27.
Title: Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
Author: Beales, Ian L P|Ogunwobi, O
PMID: 16442704
Journal: J Agric Food Chem. 2006 Feb 8;54(3):980-5.
Title: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
Author: Adams, Lynn S|Seeram, Navindra P|Aggarwal, Bharat B|Takada, Yasunari|Sand, Daniel|Heber, David
PMID: 16448212
Journal: Oncogene. 2006 Jun 15;25(25):3565-75. Epub 2006 Feb 6.
Title: Evi1 is a survival factor which conveys resistance to both TGFbeta- and taxol-mediated cell death via PI3K/AKT.
Author: Liu, Y|Chen, L|Ko, T C|Fields, A P|Thompson, E A
PMID: 16462766
Journal: Anticancer Res. 2006 Jan-Feb;26(1A):121-7.
Title: Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells.
Author: Ahn, Eun Hyun|Schroeder, Joseph J
PMID: 16475687
Journal: J Biol Chem. 2006 May 19;281(20):13915-21. Epub 2006 Feb 17.
Title: NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling.
Author: Suzuki, Atsushi|Ogura, Tsutomu|Esumi, Hiroyasu
PMID: 16488889
Journal: Cancer Res. 2006 Feb 15;66(4):2376-84.
Title: Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway.
Author: Yamaguchi, Kiyoshi|Lee, Seong-Ho|Kim, Jong-Sik|Wimalasena, Jay|Kitajima, Shigetaka|Baek, Seung Joon
PMID: 16489044
Journal: Mol Cancer Ther. 2006 Feb;5(2):309-16.
Title: RRR-alpha-tocopherol succinate down-regulates oncogenic Ras signaling.
Author: Donapaty, Sreenivasa|Louis, Somaja|Horvath, Elizabeth|Kun, Jiang|Sebti, Said M|Malafa, Mokenge P
PMID: 16505104
Journal: Mol Carcinog. 2006 May;45(5):309-19.
Title: Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis.
Author: Peng, Guang|Dixon, Dan A|Muga, Stephanie J|Smith, Theresa J|Wargovich, Michael J
PMID: 16508969
Journal: Carcinogenesis. 2006 Sep;27(9):1812-27. Epub 2006 Mar 7.
Title: Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.
Author: Guichard, Cecile|Pedruzzi, Eric|Fay, Michele|Marie, Jean-Claude|Braut-Boucher, Francoise|Daniel, Fanny|Grodet, Alain|Gougerot-Pocidalo, Marie-Anne|Chastre, Eric|Kotelevets, Larissa|Lizard, Gerard|Vandewalle, Alain|Driss, Fathi|Ogier-Denis, Eric
PMID: 16524888
Journal: Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.
Title: Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
Author: Choi, Hee-Jung|Chung, Tae-Wook|Kang, Sung-Koo|Lee, Young-Choon|Ko, Jeong-Heon|Kim, Jong-Guk|Kim, Cheorl-Ho
PMID: 16574813
Journal: Virchows Arch. 2006 Jul;449(1):48-61. Epub 2006 Apr 13.
Title: Comparative study of T84 and T84SF human colon carcinoma cells: in vitro and in vivo ultrastructural and functional characterization of cell culture and metastasis.
Author: Alessandro, Riccardo|Di Bella, Maria Antonietta|Flugy, Anna Maria|Fontana, Simona|Damiani, Francesca|Corrado, Chiara|Colomba, Paolo|Todaro, Matilde|Russo, Domenica|Santoro, Alessandra|Kohn, Elise C|De Leo, Giacomo
PMID: 16612624
Journal: Cancer Res. 2006 Apr 15;66(8):4394-401.
Title: Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.
Author: Marin, Holly E|Peraza, Marjorie A|Billin, Andrew N|Willson, Timothy M|Ward, Jerrold M|Kennett, Mary J|Gonzalez, Frank J|Peters, Jeffrey M
PMID: 16618765
Journal: Anticancer Res. 2006 Mar-Apr;26(2A):1077-84.
Title: Cancer genetics of sporadic colorectal cancer: BRAF and PI3KCA mutations, their impact on signaling and novel targeted therapies.
Author: Oikonomou, Eftychia|Pintzas, Alexandros
PMID: 16619509
Journal: Ann Surg. 2006 May;243(5):619-25; discussion 625-7.
Title: Dietary fiber enhances a tumor suppressor signaling pathway in the gut.
Author: Nguyen, Khoa A|Cao, Yanna|Chen, Justin R|Townsend, Courtney M Jr|Ko, Tien C
PMID: 16632996
Journal: Cell Signal. 2006 Nov;18(11):1967-76. Epub 2006 May 3.
Title: Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis.
Author: Fassetta, Michela|D'Alessandro, Lorenza|Coltella, Nadia|Di Renzo, Maria Flavia|Rasola, Andrea
PMID: 16677802
Journal: Int J Biochem Cell Biol. 2006;38(9):1510-7. Epub 2006 Apr 6.
Title: Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway.
Author: Busserolles, Jerome|Megias, Javier|Terencio, Maria Carmen|Alcaraz, Maria Jose
PMID: 16697692
Journal: J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):84-91.
Title: Fas-associated phosphatase-1 promotes Fas-mediated apoptosis in human colon cancer cells: novel function of FAP-1.
Author: Miyazaki, Takako|Atarashi, Yoshinari|Yasumura, Satoshi|Minatoya, Isao|Ogawa, Kohei|Iwamoto, Masaya|Minemura, Masami|Shimizu, Yukihiro|Sato, Taka-Aki|Watanabe, Akiharu|Sugiyama, Toshiro
PMID: 16706817
Journal: Mol Cancer Ther. 2006 May;5(5):1362-70.
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Safe, Stephen
PMID: 16731770
Journal: J Soc Integr Oncol. 2006 Winter;4(1):21-6.
Title: Down-regulation of prostaglandin E2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines.
Author: Lev-Ari, Shahar|Maimon, Yair|Strier, Ludmila|Kazanov, Dina|Arber, Nadir
PMID: 16737669
Journal: Ann Surg. 2006 Jun;243(6):833-42; discussion 843-4.
Title: Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma.
Author: Rychahou, Piotr G|Jackson, Lindsey N|Silva, Scott R|Rajaraman, Srinivasan|Evers, B Mark
PMID: 16772787
Journal: Hum Pathol. 2006 Aug;37(8):1022-31. Epub 2006 May 26.
Title: Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer-a tissue microarray-based approach.
Author: Lugli, Alessandro|Zlobec, Inti|Minoo, Parham|Baker, Kristi|Tornillo, Luigi|Terracciano, Luigi|Jass, Jeremy R
PMID: 16867865
Journal: Onkologie. 2006 Jul;29(7):334-41.
Title: Links between biology, prognosis and prediction of response to chemotherapy in colorectal cancer.
Author: Mader, Robert M
PMID: 16874019
Journal: Mol Cancer Ther. 2006 Jul;5(7):1883-94.
Title: Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases.
Author: Troiani, Teresa|Lockerbie, Owen|Morrow, Mark|Ciardiello, Fortunato|Eckhardt, S Gail
PMID: 16891475
Journal: Surgery. 2006 Aug;140(2):322-9.
Title: TGF-beta inhibits Akt-induced transformation in intestinal epithelial cells.
Author: Cao, Yanna|Deng, Chunyan|Townsend, Courtney M Jr|Ko, Tien C
PMID: 16904986
Journal: Mol Cancer Ther. 2006 Aug;5(8):2051-9.
Title: Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity.
Author: Buck, Elizabeth|Eyzaguirre, Alexandra|Haley, John D|Gibson, Neil W|Cagnoni, Pablo|Iwata, Kenneth K
PMID: 16928826
Journal: World J Gastroenterol. 2006 Aug 28;12(32):5140-7.
Title: Prolonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib (Iressa(TM)) and to the antiangiogenic agent ZD6474: Cytotoxic and biomolecular effects.
Author: Azzariti, Amalia|Porcelli, Letizia|Xu, Jian-Ming|Simone, Grazia Maria|Paradiso, Angelo
PMID: 16937523
Journal: World J Gastroenterol. 2006 Sep 21;12(35):5635-43.
Title: Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer.
Author: Hopfner, Michael|Sutter, Andreas P|Huether, Alexander|Baradari, Viola|Scherubl, Hans
PMID: 17007015
Journal: Cancer Res. 2006 Oct 1;66(19):9665-72.
Title: Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism.
Author: Yang, Li|Huang, Yuhui|Porta, Rut|Yanagisawa, Kiyoshi|Gonzalez, Adriana|Segi, Eric|Johnson, David H|Narumiya, Shuh|Carbone, David P
PMID: 17018624
Journal: J Med Chem. 2006 Oct 19;49(21):6290-7.
Title: Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.
Author: Fang, Lanyan|Battisti, Robert F|Cheng, Hao|Reigan, Philip|Xin, Yan|Shen, Jie|Ross, David|Chan, Kenneth K|Martin, Edward W Jr|Wang, Peng George|Sun, Duxin
PMID: 17034135
Journal: Nutr Cancer. 2006;55(2):185-94.
Title: Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.
Author: Reddy, Sudha|Rishi, Arun K|Xu, Hu|Levi, Edi|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 17044774
Journal: FEBS Lett. 2006 Dec 11;580(28-29):6565-9.
Title: Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells.
Author: Vaculova, Alena|Hofmanova, Jirina|Soucek, Karel|Kozubik, Alois
PMID: 17113582
Journal: J Biochem Mol Biol. 2006 Nov 30;39(6):649-55.
Title: NSAID activated gene (NAG-1), a modulator of tumorigenesis.
Author: Eling, Thomas E|Baek, Seung Joon|Shim, Minsub|Lee, Chang Ho
PMID: 17129398
Journal: Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19069-74. Epub 2006 Dec 5.
Title: Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression.
Author: Wang, Dingzhi|Wang, Haibin|Guo, Yong|Ning, Wei|Katkuri, Sharada|Wahli, Walter|Desvergne, Beatrice|Dey, Sudhansu K|DuBois, Raymond N
PMID: 17148604
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):578-82.
Title: [Experimental study of effect of epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in combination with irinotecan].
Author: Xu, Jian-ming|Li, Yue-min|Wang, Yan|Zhao, Chuan-hua|Yuan, Shou-jun|Yang, Wu-wei|Li, Zhi-qiang|Han, Yu|Azzariti, Amalia|Paradiso, Angelo
PMID: 17236550
Journal: J Cell Biochem. 2007 Jan 1;100(1):58-68.
Title: Insulin-like growth factors induce apoptosis as well as proliferation in LIM 1215 colon cancer cells.
Author: Fu, Ping|Thompson, Julian A|Leeding, Kerri S|Bach, Leon A
PMID: 16888814
Journal: Cell Signal. 2007 Feb;19(2):261-8. Epub 2006 Aug 9.
Title: MAGI-3 regulates LPA-induced activation of Erk and RhoA.
Author: Zhang, Huanchun|Wang, Dongsheng|Sun, Hong|Hall, Randy A|Yun, C Chris
PMID: 16904289
Journal: Int J Colorectal Dis. 2007 Apr;22(4):401-9. Epub 2006 Aug 16.
Title: The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt.
Author: Ogunwobi, Olorunseun O|Beales, Ian L P
PMID: 16912864
Journal: Oncogene. 2007 Apr 26;26(19):2781-90. Epub 2006 Oct 30.
Title: Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase.
Author: Huang, H-C|Hu, C-H|Tang, M-C|Wang, W-S|Chen, P-M|Su, Y
PMID: 17072345
Journal: Virchows Arch. 2007 Feb;450(2):151-9.
Title: Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations.
Author: Schmitz, K J|Wohlschlaeger, J|Alakus, H|Bohr, J|Stauder, M A|Worm, K|Winde, G|Schmid, K W|Baba, H A
PMID: 17149612
Journal: Cancer Lett. 2007 Jun 18;251(1):105-13. Epub 2006 Dec 18.
Title: Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer.
Author: Nozawa, Hiroaki|Watanabe, Toshiaki|Nagawa, Hirokazu
PMID: 17175097
Journal: Radiat Oncol. 2007 Jan 3;2:1.
Title: Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells.
Author: Itani, Wafica|Geara, Fady|Haykal, Joelle|Haddadin, Makhluf|Gali-Muhtasib, Hala
PMID: 17201910
Journal: Cancer Res. 2007 Jan 15;67(2):665-73.
Title: A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo.
Author: Rajput, Ashwani|Koterba, Alan P|Kreisberg, Jeffrey I|Foster, Jason M|Willson, James K V|Brattain, Michael G
PMID: 17234777
Journal: Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17239930
Journal: Virchows Arch. 2007 Mar;450(3):321-8. Epub 2007 Jan 30.
Title: Co-expression of EGF receptor, TGFalpha and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosis.
Author: Tampellini, Marco|Longo, Marina|Cappia, Susanna|Bacillo, Elisa|Alabiso, Irene|Volante, Marco|Dogliotti, Luigi|Papotti, Mauro
PMID: 17265080
Journal: Regul Pept. 2007 Jun 7;141(1-3):61-72. Epub 2007 Jan 10.
Title: Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines.
Author: Shen, Xiaoli|Mula, Ramanjaneya V R|Evers, B Mark|Falzon, Miriam
PMID: 17276526
Journal: World J Gastroenterol. 2007 Feb 7;13(5):699-708.
Title: Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Author: Chen, Wei-Chang|Lin, Mao-Song|Zhang, Bao-Feng|Fang, Jing|Zhou, Qiong|Hu, Ying|Gao, Heng-Jun
PMID: 17278192
Journal: FEBS Lett. 2007 Mar 6;581(5):865-71.
Title: Surfactin from Bacillus subtilis displays anti-proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression.
Author: Kim, Seo-Young|Kim, Joo Young|Kim, Seol-Hee|Bae, Hyun Jin|Yi, Hwaseon|Yoon, Sang Hong|Koo, Bon Sung|Kwon, Moosik|Cho, Jae Youl|Lee, Choong-Eun|Hong, Sungyoul
PMID: 17292358
Journal: FASEB J. 2007 Jun;21(8):1730-41. Epub 2007 Feb 22.
Title: FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway.
Author: Thamilselvan, Vijayalakshmi|Craig, David H|Basson, Marc D
PMID: 17317726
Journal: Free Radic Biol Med. 2007 Apr 15;42(8):1211-21.
Title: Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects.
Author: Hong, Jungil|Kwon, Seok Joo|Sang, Shengmin|Ju, Jihyeung|Zhou, Jian-nian|Ho, Chi-Tang|Huang, Mou-Tuan|Yang, Chung S
PMID: 17382202
Journal: Cancer Res. 2007 Apr 1;67(7):2922-6.
Title: PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Author: Wang, Haihe|Quah, Samantha Yiling|Dong, Jing Ming|Manser, Edward|Tang, Jing Ping|Zeng, Qi
PMID: 17409395
Journal: Dig Dis Sci. 2007 Sep;52(9):2292-300. Epub 2007 Apr 5.
Title: Stem cell factor/c-kit receptor signaling enhances the proliferation and invasion of colorectal cancer cells through the PI3K/Akt pathway.
Author: Yasuda, Akira|Sawai, Hirozumi|Takahashi, Hiroki|Ochi, Nobuo|Matsuo, Yoichi|Funahashi, Hitoshi|Sato, Mikinori|Okada, Yuji|Takeyama, Hiromitsu|Manabe, Tadao
PMID: 17410437
Journal: Gut. 2007 Sep;56(9):1257-65. Epub 2007 Apr 20.
Title: Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
Author: Dambacher, Julia|Beigel, Florian|Seiderer, Julia|Haller, Dirk|Goke, Burkhard|Auernhammer, Christoph J|Brand, Stephan
PMID: 17449633
Journal: Mol Cell Biol. 2007 Jul;27(13):4917-30. Epub 2007 Apr 23.
Title: Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression.
Author: Delpuech, Oona|Griffiths, Beatrice|East, Philip|Essafi, Abdelkader|Lam, Eric W-F|Burgering, Boudewijn|Downward, Julian|Schulze, Almut
PMID: 17452451
Journal: J Biol Chem. 2007 Jul 6;282(27):19273-81.
Title: Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.
Author: Kaneko, Reiko|Tsuji, Naoki|Asanuma, Koichi|Tanabe, Hiromi|Kobayashi, Daisuke|Watanabe, Naoki
PMID: 17472962
Journal: Mol Pharmacol. 2007 Aug;72(2):395-406.
Title: Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
Author: Merighi, Stefania|Benini, Annalisa|Mirandola, Prisco|Gessi, Stefania|Varani, Katia|Simioni, Carolina|Leung, Edward|Maclennan, Stephen|Baraldi, Pier Giovanni|Borea, Pier Andrea
PMID: 17488804
Journal: Mol Cancer Ther. 2007 May;6(5):1579-87.
Title: ZD1839 induces p15INK4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Author: Koyama, Makoto|Matsuzaki, Youichirou|Yogosawa, Shingo|Hitomi, Toshiaki|Kawanaka, Mayumi|Sakai, Toshiyuki
PMID: 17513607
Journal: Chin Med J (Engl). 2007 May 5;120(9):743-8.
Title: Inducing effects of hepatocyte growth factor on the expression of vascular endothelial growth factor in human colorectal carcinoma cells through MEK and PI3K signaling pathways.
Author: Zhang, Yu-hua|Wei, Wei|Xu, Hao|Wang, Yan-yan|Wu, Wen-xi
PMID: 17531111
Journal: Cancer Res. 2007 Jun 1;67(11):5248-57.
Title: Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.
Author: McEwan, David G|Brunton, Valerie G|Baillie, George S|Leslie, Nicholas R|Houslay, Miles D|Frame, Margaret C
PMID: 17545604
Journal: J Exp Ther Oncol. 2007;6(3):205-17.
Title: Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells.
Author: Herynk, Matthew H|Zhang, Jing|Parikh, Nila U|Gallick, Gary E
PMID: 17552361
Journal: Bioorg Med Chem. 2007 Aug 15;15(16):5620-8. Epub 2007 May 18.
Title: Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells.
Author: Nakagawa, Yoshihito|Iinuma, Munekazu|Naoe, Tomoki|Nozawa, Yoshinori|Akao, Yukihiro
PMID: 17553685
Journal: World J Gastroenterol. 2007 May 28;13(20):2811-8.
Title: Mechanisms involved in Korean mistletoe lectin-induced apoptosis of cancer cells.
Author: Khil, Lee-Yong|Kim, Wi|Lyu, Suyun|Park, Won-Bong|Yoon, Ji-Won|Jun, Hee-Sook
PMID: 17569116
Journal: Cancer Res. 2007 Jun 15;67(12):5851-8.
Title: Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model.
Author: Guo, Xiao-Ning|Rajput, Ashwani|Rose, Rebecca|Hauser, Jennie|Beko, Alexander|Kuropatwinski, Karen|LeVea, Charles|Hoffman, Robert M|Brattain, Michael G|Wang, Jing
PMID: 17575153
Journal: Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author: Mitchell, Clint|Kabolizadeh, Peyman|Ryan, John|Roberts, John D|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Hagan, Michael P|Farrell, Nicholas P|Grant, Steven|Dent, Paul
PMID: 17578896
Journal: Br J Cancer. 2007 Jul 2;97(1):92-7. Epub 2007 Jun 19.
Title: Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options.
Author: Scartozzi, M|Bearzi, I|Berardi, R|Mandolesi, A|Pierantoni, C|Cascinu, S
PMID: 17579627
Journal: Int J Cancer. 2007 Nov 15;121(10):2172-80.
Title: The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.
Author: Greenhough, Alexander|Patsos, Helena A|Williams, Ann C|Paraskeva, Christos
PMID: 17583570
Journal: Int J Cancer. 2007 Oct 15;121(8):1771-8.
Title: PIK3CA mutation is predictive of poor survival in patients with colorectal cancer.
Author: Kato, Shunsuke|Iida, Satoru|Higuchi, Tetsuro|Ishikawa, Toshiaki|Takagi, Yoko|Yasuno, Masamichi|Enomoto, Masayuki|Uetake, Hiroyuki|Sugihara, Kenichi
PMID: 17590872
Journal: Exp Mol Pathol. 2007 Oct;83(2):207-15. Epub 2007 May 13.
Title: CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation.
Author: Subramaniam, Venkateswaran|Vincent, Isabella R|Gardner, Helena|Chan, Emily|Dhamko, Helena|Jothy, Serge
PMID: 17599831
Journal: Cancer Biol Ther. 2007 Jul;6(7):1121-9.
Title: Blocking tumorigenic activities of colorectal cancer cells by a splicing RON receptor variant defective in the tyrosine kinase domain.
Author: Wang, Ming-Hai|Lao, Wei-Feng|Wang, Da|Luo, Yu Lan|Yao, Hang-Ping
PMID: 17611409
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G673-81.
Title: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.
Author: Leone, Vincenza|di Palma, Antonella|Ricchi, Paolo|Acquaviva, Fabio|Giannouli, Maria|Di Prisco, Anna Maria|Iuliano, Francesca|Acquaviva, Angela M
PMID: 17640974
Journal: Mol Cancer Ther. 2007 Aug;6(8):2158-67. Epub 2007 Aug 1.
Title: A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo.
Author: Ji, Qun-sheng|Mulvihill, Mark J|Rosenfeld-Franklin, Maryland|Cooke, Andrew|Feng, Lixin|Mak, Gilda|O'Connor, Matthew|Yao, Yan|Pirritt, Caroline|Buck, Elizabeth|Eyzaguirre, Alexandra|Arnold, Lee D|Gibson, Neil W|Pachter, Jonathan A
PMID: 17671083
Journal: Cancer Res. 2007 Aug 1;67(15):7106-12.
Title: Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
Author: Ma, Li|Teruya-Feldstein, Julie|Bonner, Pauline|Bernardi, Rosa|Franz, David Neal|Witte, David|Cordon-Cardo, Carlos|Pandolfi, Pier Paolo
PMID: 17671177
Journal: Cancer Res. 2007 Aug 1;67(15):7266-74.
Title: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.
Author: Rengifo-Cam, William|Umar, Shahid|Sarkar, Shubhashish|Singh, Pomila
PMID: 17671195
Journal: Carcinogenesis. 2007 Dec;28(12):2476-83. Epub 2007 Aug 11.
Title: Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: roles of osteopontin.
Author: Shao, Jinyi|Washington, M Kay|Saxena, Romil|Sheng, Hongmiao
PMID: 17693663
Journal: Mol Cancer Ther. 2007 Aug;6(8):2220-9.
Title: Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
Author: Hao, Honglin|Muniz-Medina, Vanessa M|Mehta, Heena|Thomas, Nancy E|Khazak, Vladimir|Der, Channing J|Shields, Janiel M
PMID: 17699719
Journal: Surgery. 2007 Sep;142(3):384-92.
Title: Thermal sensitization through ROS modulation: a strategy to improve the efficacy of hyperthermic intraperitoneal chemotherapy.
Author: Wang, Chia-Chi|Chen, Fei|Kim, Eugene|Harrison, Lawrence E
PMID: 17723891
Journal: Cancer Res. 2007 Sep 1;67(17):8240-7.
Title: Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab.
Author: Lu, Yang|Li, Xinqun|Liang, Ke|Luwor, Rodney|Siddik, Zahid H|Mills, Gordon B|Mendelsohn, John|Fan, Zhen
PMID: 17804738
Journal: Zhonghua Yi Xue Za Zhi. 2007 Jun 26;87(24):1704-8.
Title: [Molecular mechanism of gastrin increasing colon cancer cells' invasion].
Author: Cao, Jun|Yu, Jie-ping|Zhou, Lan|Song, Wen-chong|Luo, He-sheng|Yu, Hong-gang
PMID: 17825155
Journal: Cancer. 2007 Oct 15;110(8):1697-707.
Title: Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer.
Author: Mudduluru, Giridhar|Medved, Fabian|Grobholz, Rainer|Jost, Camela|Gruber, Anette|Leupold, Joerg H|Post, Stefan|Jansen, Aaron|Colburn, Nancy H|Allgayer, Heike
PMID: 17849461
Journal: Mol Biol Cell. 2007 Nov;18(11):4591-602. Epub 2007 Sep 12.
Title: Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis.
Author: Hashimoto, Yosuke|Parsons, Maddy|Adams, Josephine C
PMID: 17855511
Journal: J Pathol. 2007 Nov;213(3):266-74.
Title: A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice.
Author: Ploplis, V A|Tipton, H|Menchen, H|Castellino, F J
PMID: 17893885
Journal: Cancer Res. 2007 Oct 1;67(19):9286-93.
Title: Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation.
Author: Ying, Lei|Hofseth, Anne B|Browning, Darren D|Nagarkatti, Mitzi|Nagarkatti, Prakash S|Hofseth, Lorne J
PMID: 17909036
Journal: Cancer Lett. 2007 Dec 8;258(1):144-53. Epub 2007 Oct 17.
Title: Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line.
Author: Engelbrecht, A-M|Mattheyse, M|Ellis, B|Loos, B|Thomas, M|Smith, R|Peters, S|Smith, C|Myburgh, K
PMID: 17923279
Journal: Cancer Biol Ther. 2007 Oct;6(10):1649-53. Epub 2007 Aug 31.
Title: Multimodality optical imaging and 18F-FDG uptake in wild-type p53-containing and p53-null human colon tumor xenografts.
Author: Wang, Shulin|Mintz, Akiva|Mochizuki, Kenjiro|Dorsey, Jay F|Ackermann, Joseph M|Alavi, Abass|El-Deiry, Wafik S
PMID: 17932466
Journal: Cancer Res. 2007 Oct 15;67(20):9937-44.
Title: Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.
Author: Shen, Guoxiang|Khor, Tin Oo|Hu, Rong|Yu, Siwang|Nair, Sujit|Ho, Chi-Tang|Reddy, Bandaru S|Huang, Mou-Tuan|Newmark, Harold L|Kong, Ah-Ng Tony
PMID: 17942926
Journal: Clin Colorectal Cancer. 2007 Sep;6(9):652-6.
Title: Activation of the serine/threonine protein kinase AKT during the progression of colorectal neoplasia.
Author: Saglam, Ozlen|Garrett, Christopher R|Boulware, David|Sayegh, Zena|Shibata, David|Malafa, Mokenge|Yeatman, Timothy|Cheng, Jin Q|Sebti, Said|Coppola, Domenico
PMID: 17945038
Journal: ChemMedChem. 2007 Dec;2(12):1789-98.
Title: Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
Author: Gajewiak, Joanna|Tsukahara, Ryoko|Tsukahara, Tamotsu|Fujiwara, Yuko|Yu, Shuanxing|Lu, Yiling|Murph, Mandi|Mills, Gordon B|Tigyi, Gabor|Prestwich, Glenn D
PMID: 17952880
Journal: Cancer Lett. 2007 Dec 18;258(2):241-52. Epub 2007 Oct 26.
Title: PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer.
Author: Shen, Xiaoli|Rychahou, Piotr G|Evers, B Mark|Falzon, Miriam
PMID: 17964713
Journal: World J Gastroenterol. 2007 Nov 28;13(44):5845-56.
Title: Exploiting novel molecular targets in gastrointestinal cancers.
Author: Ma, Wen W|Hidalgo, Manuel
PMID: 17990350
Journal: Cancer Biol Ther. 2007 Aug;6(8):1313-7.
Title: BMP suppresses PTEN expression via RAS/ERK signaling.
Author: Beck, Stayce E|Carethers, John M
PMID: 18059158
Journal: Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20926-31.
Title: Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Author: Kaneda, Atsushi|Wang, Chiaochun J|Cheong, Raymond|Timp, Winston|Onyango, Patrick|Wen, Bo|Iacobuzio-Donahue, Christine A|Ohlsson, Rolf|Andraos, Rita|Pearson, Mark A|Sharov, Alexei A|Longo, Dan L|Ko, Minoru S H|Levchenko, Andre|Feinberg, Andrew P
PMID: 18087038
Journal: Clin Cancer Res. 2007 Dec 15;13(24):7432-40.
Title: Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab.
Author: Prewett, Marie|Deevi, Dhanvanthri S|Bassi, Rajiv|Fan, Fan|Ellis, Lee M|Hicklin, Daniel J|Tonra, James R
PMID: 18094427
Journal: PLoS One. 2007 Dec 26;2(12):e1353.
Title: Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice.
Author: Chan, Carlos H F|Camacho-Leal, Pilar|Stanners, Clifford P
PMID: 18159236
Journal: J Physiol Pharmacol. 2007 Dec;58(4):793-801.
Title: Transcriptional upregulation of gastrin in response to peroxisome proliferator-activated receptor gamma agonist triggers cell survival pathways.
Author: Ptak-Belowska, A|Pawlik, M W|Krzysiek-Maczka, G|Brzozowski, T|Pawlik, W W
PMID: 18195488
Journal: Curr Med Chem. 2007;14(29):3122-38.
Title: Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Author: Stravopodis, Dimitrios J|Margaritis, Lukas H|Voutsinas, Gerassimos E
PMID: 18220746
Journal: Pharm Res. 2008 Feb;25(2):387-99. Epub 2007 Jul 27.
Title: Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Author: Nair, Sujit|Hebbar, Vidya|Shen, Guoxiang|Gopalakrishnan, Avantika|Khor, Tin Oo|Yu, Siwang|Xu, Changjiang|Kong, Ah-Ng
PMID: 17657594
Journal: Int J Cancer. 2008 Jan 15;122(2):267-73.
Title: Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.
Author: Patel, Bhaumik B|Sengupta, Radha|Qazi, Sadia|Vachhani, Hetal|Yu, Yingjie|Rishi, Arun K|Majumdar, Adhip P N
PMID: 17918158
Journal: Cell Signal. 2008 Jan;20(1):83-93. Epub 2007 Sep 11.
Title: Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.
Author: He, Hong|Yim, Mildred|Liu, Kevin H|Cody, Stephen C|Shulkes, Arthur|Baldwin, Graham S
PMID: 17936584
Journal: Biochem Pharmacol. 2008 Jan 15;75(2):427-37.
Title: Interaction between celecoxib and docetaxel or cisplatin in human cell lines of ovarian cancer and colon cancer is independent of COX-2 expression levels.
Author: Bijman, Marcel N A|Hermelink, Cristian A|van Berkel, Maria P A|Laan, Adrie C|Janmaat, Maarten L|Peters, Godefridus J|Boven, Epie
PMID: 17936723
Journal: Int J Cancer. 2008 Mar 15;122(6):1426-9.
Title: Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB.
Author: Bhat, Uppoor G|Gartel, Andrei L
PMID: 17999411
Journal: DNA Repair (Amst). 2008 Feb 1;7(2):239-52.
Title: Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
Author: Hill, Richard|Leidal, Andrew M|Madureira, Patricia A|Gillis, Laura D|Cochrane, Haley K|Waisman, David M|Chiu, Arthur|Lee, Patrick W K
PMID: 18024214
Journal: J Clin Invest. 2008 Jan;118(1):352-63.
Title: Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
Author: Scamuffa, Nathalie|Siegfried, Geraldine|Bontemps, Yannick|Ma, Liming|Basak, Ajoy|Cherel, Ghislaine|Calvo, Fabien|Seidah, Nabil G|Khatib, Abdel-Majid
PMID: 18064302
Journal: J Cell Physiol. 2008 May;215(2):538-49.
Title: Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
Author: Raufman, Jean-Pierre|Shant, Jasleen|Guo, Chang Yue|Roy, Sanjit|Cheng, Kunrong
PMID: 18064605
Journal: J Biol Chem. 2008 Mar 7;283(10):6300-11. Epub 2007 Dec 27.
Title: The phosphatase PHLPP controls the cellular levels of protein kinase C.
Author: Gao, Tianyan|Brognard, John|Newton, Alexandra C
PMID: 18162466
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Oncogene. 2008 Jun 5;27(25):3539-45.
Title: Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population.
Author: Abubaker, J|Bavi, P|Al-Harbi, S|Ibrahim, M|Siraj, A K|Al-Sanea, N|Abduljabbar, A|Ashari, L H|Alhomoud, S|Al-Dayel, F|Uddin, S|Al-Kuraya, K S
PMID: 18193083
Journal: J Biol Chem. 2008 Apr 4;283(14):9454-64.
Title: A novel role for villin in intestinal epithelial cell survival and homeostasis.
Author: Wang, Yaohong|Srinivasan, Kamalakkannan|Siddiqui, Mohammad Rizwan|George, Sudeep P|Tomar, Alok|Khurana, Seema
PMID: 18198174
Journal: Clin Cancer Res. 2008 Feb 1;14(3):892-900.
Title: Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.
Author: Manegold, Philipp C|Paringer, Carmen|Kulka, Ulrike|Krimmel, Klaus|Eichhorn, Martin E|Wilkowski, Ralf|Jauch, Karl-Walter|Guba, Markus|Bruns, Christiane J
PMID: 18245553
Journal: Pflugers Arch. 2008 Aug;456(5):847-55.
Title: Upregulation of colonic ion channels in APC ( Min/+ ) mice.
Author: Ousingsawat, Jiraporn|Spitzner, Melanie|Schreiber, Rainer|Kunzelmann, Karl
PMID: 18247045
Journal: Neoplasia. 2008 Feb;10(2):140-8.
Title: Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells.
Author: Henkhaus, Rebecca S|Roy, Upal Kunal Basu|Cavallo-Medved, Dora|Sloane, Bonnie F|Gerner, Eugene W|Ignatenko, Natalia A
PMID: 18283336
Journal: Cell Mol Life Sci. 2008 Jun;65(11):1631-52.
Title: Curcumin: from ancient medicine to current clinical trials.
Author: Hatcher, H|Planalp, R|Cho, J|Torti, F M|Torti, S V
PMID: 18324353
Journal: J Biol Chem. 2008 May 23;283(21):14335-44.
Title: Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
Author: Misra, Suniti|Obeid, Lina M|Hannun, Yusuf A|Minamisawa, Susumu|Berger, Franklin G|Markwald, Roger R|Toole, Bryan P|Ghatak, Shibnath
PMID: 18326857
Journal: J Clin Oncol. 2008 Apr 1;26(10):1603-10.
Title: Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
Author: Tabernero, Josep|Rojo, Federico|Calvo, Emiliano|Burris, Howard|Judson, Ian|Hazell, Katharine|Martinelli, Erika|Ramon y Cajal, Santiago|Jones, Suzanne|Vidal, Laura|Shand, Nicholas|Macarulla, Teresa|Ramos, Francisco Javier|Dimitrijevic, Sasa|Zoellner, Ulrik
PMID: 18332469
Journal: Cancer Res. 2008 Mar 15;68(6):1962-9.
Title: Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity.
Author: Subramaniam, Dharmalingam|May, Randal|Sureban, Sripathi M|Lee, Katherine B|George, Robert|Kuppusamy, Periannan|Ramanujam, Rama P|Hideg, Kalman|Dieckgraefe, Brian K|Houchen, Courtney W|Anant, Shrikant
PMID: 18339878
Journal: Cancer Res. 2008 Mar 15;68(6):2043-50.
Title: Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Author: Singh, Rana P|Gu, Mallikarjuna|Agarwal, Rajesh
PMID: 18339887
Journal: Virchows Arch. 2008 May;452(5):535-44.
Title: Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Author: Greijer, Astrid E|Delis-van Diemen, Pien M|Fijneman, Remond J A|Giles, Rachel H|Voest, Emile E|van Hinsbergh, Victor W M|Meijer, Gerrit A
PMID: 18351386
Journal: Cancer Res. 2008 Apr 1;68(7):2384-90.
Title: Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Author: Zeng, Xuehuo|Kinsella, Timothy J
PMID: 18381446
Journal: J Cell Physiol. 2008 Sep;216(3):698-707.
Title: Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells.
Author: Cascone, Tina|Morelli, Maria Pia|Morgillo, Floriana|Kim, Woo-Young|Rodolico, Gabriella|Pepe, Stefano|Tortora, Giampaolo|Berrino, Liberato|Lee, Ho-Young|Heymach, John V|Ciardiello, Fortunato
PMID: 18381602
Journal: Curr Med Chem. 2008;15(10):978-90.
Title: ANTI-ADHESION evolves to a promising therapeutic concept in oncology.
Author: Schmidmaier, R|Baumann, P
PMID: 18393855
Journal: Mol Pharmacol. 2008 Jul;74(1):173-83.
Title: AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
Author: Caporali, Simona|Levati, Lauretta|Starace, Giuseppe|Ragone, Gianluca|Bonmassar, Enzo|Alvino, Ester|D'Atri, Stefania
PMID: 18413665
Journal: Mol Cancer Ther. 2008 Apr;7(4):915-22.
Title: Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.
Author: Serova, Maria|Ghoul, Aida|Benhadji, Karim A|Faivre, Sandrine|Le Tourneau, Christophe|Cvitkovic, Esteban|Lokiec, Francois|Lord, Janet|Ogbourne, Steven M|Calvo, Fabien|Raymond, Eric
PMID: 18413805
Journal: Clin Cancer Res. 2008 Apr 15;14(8):2253-62.
Title: Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model.
Author: Dougherty, Urszula|Sehdev, Amikar|Cerda, Sonia|Mustafi, Reba|Little, Nathaniel|Yuan, Weihua|Jagadeeswaran, Sujatha|Chumsangsri, Anusara|Delgado, Jorge|Tretiakova, Maria|Joseph, Loren|Hart, John|Cohen, Ezra E W|Aluri, Lata|Fichera, Alessandro|Bissonnette,
PMID: 18413814
Journal: Am J Surg. 2008 Jun;195(6):719-25.
Title: Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence?
Author: Colakoglu, Tamer|Yildirim, Sedat|Kayaselcuk, Fazilet|Nursal, Tarik Zafer|Ezer, Ali|Noyan, Turgut|Karakayali, Hamdi|Haberal, Mehmet
PMID: 18440486
Journal: Cancer Res. 2008 May 1;68(9):3152-60.
Title: Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells.
Author: Wang, Jing|Yang, Limin|Yang, Junhua|Kuropatwinski, Karen|Wang, Wang|Liu, Xiao-Qiong|Hauser, Jennie|Brattain, Michael G
PMID: 18451140
Journal: Biochem Pharmacol. 2008 Jun 15;75(12):2345-55.
Title: Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw|Lee, Yong J
PMID: 18455702
Journal: Neoplasia. 2008 May;10(5):489-500.
Title: Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors.
Author: Kuwai, Toshio|Nakamura, Toru|Sasaki, Takamitsu|Kim, Sun-Jin|Fan, Dominic|Villares, Gabriel J|Zigler, Maya|Wang, Hua|Bar-Eli, Menashe|Kerbel, Robert S|Fidler, Isaiah J
PMID: 18472966
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.
Title: Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
Author: Lee, Jenq-Chang|Won, Shen-Jeu|Chao, Chien-Lin|Wu, Feng-Ling|Liu, Hsiao-Sheng|Ling, Pin|Lin, Chun-Nan|Su, Chun-Li
PMID: 18485277
Journal: Am J Health Syst Pharm. 2008 Jun 1;65(11 Suppl 4):S15-21; quiz S22-4.
Title: Current and emerging therapies for metastatic colorectal cancer: applying research findings to clinical practice.
Author: Hecht, J Randolph
PMID: 18499885
Journal: Growth Horm IGF Res. 2008 Dec;18(6):487-96.
Title: Recombinant human insulin-like growth factor-binding protein 3 inhibits tumor growth and targets the Akt pathway in lung and colon cancer models.
Author: Alami, Nezha|Page, Viviane|Yu, Qingnan|Jerome, Lori|Paterson, Jesse|Shiry, Laura|Leyland-Jones, Brian
PMID: 18502161
Journal: Neoplasia. 2008 Jun;10(6):534-41.
Title: PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author: Nosho, Katsuhiko|Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Zepf, Dimity|Yan, Liying|Longtine, Janina A|Fuchs, Charles S|Ogino, Shuji
PMID: 18516290
Journal: Mol Nutr Food Res. 2008 Jun;52(6):646-54.
Title: Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway.
Author: Tang, Feng-Yao|Shih, Chung-Jin|Cheng, Li-Hao|Ho, Hsin-Jung|Chen, Hung-Jiun
PMID: 18537129
Journal: Mol Cancer Ther. 2008 Jun;7(6):1376-85.
Title: Eps8 decreases chemosensitivity and affects survival of cervical cancer patients.
Author: Chen, Yun-Ju|Shen, Meng-Ru|Chen, Yen-Jen|Maa, Ming-Chei|Leu, Tzeng-Horng
PMID: 18566210
Journal: J Proteome Res. 2008 Aug;7(8):3507-15.
Title: Evaluation of hepatic-metastasis risk of colorectal cancer upon the protein signature of PI3K/AKT pathway.
Author: Kang, Bin|Hao, Chunyi|Wang, Hongyi|Zhang, Jun|Xing, Rui|Shao, Jianmin|Li, Wenmei|Xu, Ningzhi|Lu, Youyong|Liu, Siqi
PMID: 18570457
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 May;39(3):364-7.
Title: [Effects of PI3K signaling pathway on pathogenesis of ulcerative colitis].
Author: Huang, Xiao-Li|Zheng, Yu-Xia|Liao, Zai-Bo|Yin, Jing|Gan, Hua-Tian
PMID: 18575316
Journal: Br J Pharmacol. 2008 Sep;155(2):198-209.
Title: Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation.
Author: Colucci, R|Blandizzi, C|Ghisu, N|Florio, T|Del Tacca, M
PMID: 18587421
Journal: Ann Surg Oncol. 2008 Oct;15(10):2954-64.
Title: Mechanisms driving local breast cancer recurrence in a model of breast-conserving surgery.
Author: Smith, Myles J|Culhane, Aedin C|Killeen, Shane|Kelly, Maura A|Wang, Jiang H|Cotter, Thomas G|Redmond, Henry P
PMID: 18622646
Journal: Connect Tissue Res. 2008;49(3):219-24.
Title: Hyaluronan, CD44, and cyclooxygenase-2 in colon cancer.
Author: Misra, Suniti|Hascall, Vincent C|Berger, Franklin G|Markwald, Roger R|Ghatak, Shibnath
PMID: 18661347
Journal: Genes Chromosomes Cancer. 2008 Nov;47(11):939-46.
Title: The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers.
Author: Guo, Chunguang|Sah, Jerome F|Beard, Lydia|Willson, James K V|Markowitz, Sanford D|Guda, Kishore
PMID: 18663744
Journal: Exp Cell Res. 2008 Oct 1;314(16):3017-26.
Title: Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.
Author: Ikeda, Ryuji|Iwashita, Ken-ichi|Sumizawa, Tomoyuki|Beppu, Shun-ichi|Tabata, Sho|Tajitsu, Yusuke|Shimamoto, Yuichi|Yoshida, Kenichi|Furukawa, Tatsuhiko|Che, Xiao-Fang|Yamaguchi, Tatsuya|Ushiyama, Mina|Miyawaki, Akihiko|Takeda, Yasuo|Yamamoto, Masatatsu|Zha
PMID: 18671966
Journal: Cell Biol Int. 2008 Oct;32(10):1215-22.
Title: Identification of potential genes/proteins regulated by Tiam1 in colorectal cancer by microarray analysis and proteome analysis.
Author: Liu, Li|Wang, Shuang|Zhang, Qingling|Ding, Yanqing
PMID: 18675922
Journal: J Clin Invest. 2008 Sep;118(9):3170-80.
Title: Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice.
Author: Craig, David H|Owen, Cheri R|Conway, William C|Walsh, Mary F|Downey, Christina|Basson, Marc D
PMID: 18704196
Journal: Int Immunopharmacol. 2008 Dec 20;8(13-14):1854-8.
Title: Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation.
Author: Sun, Qiaoling|Zheng, Yuanyuan|Liu, Qiuyan|Cao, Xuetao
PMID: 18789402
Journal: Mol Cancer Ther. 2008 Sep;7(9):3064-70.
Title: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells.
Author: Fan, Fan|Gray, Michael J|Dallas, Nikolaos A|Yang, Anthony D|Van Buren, George 2nd|Camp, E Ramsay|Ellis, Lee M
PMID: 18790786
Journal: Cancer Res. 2008 Sep 15;68(18):7270-7.
Title: LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Author: Zhong, Diansheng|Liu, Xiuju|Khuri, Fadlo R|Sun, Shi-Yong|Vertino, Paula M|Zhou, Wei
PMID: 18794113
Journal: Bioorg Med Chem. 2008 Oct 1;16(19):9065-78.
Title: Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties.
Author: Ortin, Irene|Gonzalez, Juan Francisco|Cuesta, Elena de la|Manguan-Garcia, Cristina|Perona, Rosario|Avendano, Carmen
PMID: 18799316
Journal: Biochim Biophys Acta. 2008 Dec;1783(12):2323-31.
Title: Early adhesion induces interaction of FAK and Fyn in lipid domains and activates raft-dependent Akt signaling in SW480 colon cancer cells.
Author: Baillat, Gilbert|Siret, Carole|Delamarre, Estelle|Luis, Jose
PMID: 18805444
Journal: Br J Cancer. 2008 Oct 21;99(8):1265-8.
Title: A novel AKT3 mutation in melanoma tumours and cell lines.
Author: Davies, M A|Stemke-Hale, K|Tellez, C|Calderone, T L|Deng, W|Prieto, V G|Lazar, A J F|Gershenwald, J E|Mills, G B
PMID: 18813315
Journal: Cancer Res. 2008 Oct 1;68(19):8004-13.
Title: Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type I insulin-like growth factor receptor and epidermal growth factor receptor.
Author: Hu, Yi Peter|Patil, Sandip B|Panasiewicz, Michelle|Li, Wenhui|Hauser, Jennie|Humphrey, Lisa E|Brattain, Michael G
PMID: 18829558
Journal: Inflamm Res. 2008 Oct;57(10):472-8.
Title: The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.
Author: Navarro-Peran, E|Cabezas-Herrera, J|Sanchez-Del-Campo, L|Garcia-Canovas, F|Rodriguez-Lopez, J N
PMID: 18830563
Journal: Biochem Biophys Res Commun. 2008 Dec 12;377(2):622-6.
Title: PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells.
Author: Tanaka, Yusuke|Sekiguchi, Fumiko|Hong, Hao|Kawabata, Atsufumi
PMID: 18854173
Journal: Cancer Res. 2008 Oct 15;68(20):8573-81.
Title: Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos.
Author: Subramaniam, Dharmalingam|Giridharan, Periyasamy|Murmu, Nabendu|Shankaranarayanan, Nallakandy P|May, Randal|Houchen, Courtney W|Ramanujam, Rama P|Balakrishnan, Arun|Vishwakarma, Ram A|Anant, Shrikant
PMID: 18922933
Journal: Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20315-20.
Title: Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.
Author: Rychahou, Piotr G|Kang, JungHee|Gulhati, Pat|Doan, Hung Q|Chen, L Andy|Xiao, Shu-Yuan|Chung, Dai H|Evers, B Mark
PMID: 19075230
Journal: Int J Mol Sci. 2008 Mar;9(3):355-70. Epub 2008 Mar 14.
Title: Anti-cancer effects of xanthones from pericarps of mangosteen.
Author: Akao, Yukihiro|Nakagawa, Yoshihito|Iinuma, Munekazu|Nozawa, Yoshinori
PMID: 19325754
Journal: Gene Regul Syst Bio. 2008 May 2;2:163-176.
Title: Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling.
Author: Guruswamy, Suresh|Rao, Chinthalapally V
PMID: 19763245
Journal: J Nutr Biochem. 2009 Feb;20(2):106-14.
Title: Docosahexaenoic acid induces apoptosis in colorectal carcinoma cells by modulating the PI3 kinase and p38 MAPK pathways.
Author: Toit-Kohn, Joe-Lin du|Louw, Louise|Engelbrecht, Anna-Mart
PMID: 18479896
Journal: Ann Oncol. 2009 Jan;20(1):84-90.
Title: PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.
Author: Perrone, F|Lampis, A|Orsenigo, M|Di Bartolomeo, M|Gevorgyan, A|Losa, M|Frattini, M|Riva, C|Andreola, S|Bajetta, E|Bertario, L|Leo, E|Pierotti, M A|Pilotti, S
PMID: 18669866
Journal: J Nutr Biochem. 2009 Jun;20(6):426-34.
Title: Concomitant supplementation of lycopene and eicosapentaenoic acid inhibits the proliferation of human colon cancer cells.
Author: Tang, Feng-Yao|Cho, Hsin-Ju|Pai, Man-Hui|Chen, Ye-Hsin
PMID: 18708285
Journal: Crit Rev Oncol Hematol. 2009 Jan;69(1):45-55.
Title: Recent advances in colorectal cancer genetics and diagnostics.
Author: Cheah, Peh Yean
PMID: 18774731
Journal: Cancer Lett. 2009 Jan 18;273(2):225-32.
Title: Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression.
Author: Al-Salihi, Mazin A|Terrece Pearman, A|Doan, Thao|Reichert, Ethan C|Rosenberg, Daniel W|Prescott, Stephen M|Stafforini, Diana M|Topham, Matthew K
PMID: 18790560
Journal: J Cancer Res Clin Oncol. 2009 Mar;135(3):395-402.
Title: Epidermal growth factor receptor status and persistent activation of Akt and p44/42 MAPK pathways correlate with the effect of cetuximab in head and neck and colon cancer cell lines.
Author: Yamatodani, Takashi|Ekblad, Lars|Kjellen, Elisabeth|Johnsson, Anders|Mineta, Hiroyuki|Wennerberg, Johan
PMID: 18813952
Journal: Oncogene. 2009 Jan 15;28(2):157-69.
Title: Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Author: Smith, J R|Clarke, P A|de Billy, E|Workman, P
PMID: 18931700
Journal: FASEB J. 2009 Mar;23(3):916-28.
Title: TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness.
Author: Chastre, Eric|Abdessamad, Mahmoud|Kruglov, Alexey|Bruyneel, Erik|Bracke, Marc|Di Gioia, Yolande|Beckerle, Mary C|van Roy, Frans|Kotelevets, Larissa
PMID: 19017743
Journal: Exp Cell Res. 2009 Feb 1;315(3):432-50.
Title: Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.
Author: Shant, Jasleen|Cheng, Kunrong|Marasa, Bernard S|Wang, Jian-Ying|Raufman, Jean-Pierre
PMID: 19056378
Journal: J Nutr. 2009 Jan;139(1):101-5.
Title: Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis.
Author: Warren, Cynthia A|Paulhill, Kimberly J|Davidson, Laurie A|Lupton, Joanne R|Taddeo, Stella S|Hong, Mee Young|Carroll, Raymond J|Chapkin, Robert S|Turner, Nancy D
PMID: 19056647
Journal: Oncogene. 2009 Feb 19;28(7):994-1004.
Title: Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis.
Author: Liu, J|Weiss, H L|Rychahou, P|Jackson, L N|Evers, B M|Gao, T
PMID: 19079341
Journal: Int J Oncol. 2009 Jan;34(1):69-77.
Title: p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB.
Author: Bottini, C|Platini, F|Rinaldi, M|Leutner, M|Alabiso, O|Garavoglia, M|Tessitore, L
PMID: 19082479
Journal: Plant Foods Hum Nutr. 2009 Mar;64(1):11-7.
Title: Antiproliferation and apoptosis on RKO colon cancer by Millingtonia hortensis.
Author: Tansuwanwong, Siwapong|Yamamoto, Hiroyuki|Imai, Kohzoh|Vinitketkumnuen, Usanee
PMID: 19083098
Journal: Brain Res. 2009 Feb 23;1256:85-91.
Title: Intra-hippocampal administration of the VEGF receptor blocker PTK787/ZK222584 impairs long-term memory.
Author: Pati, Shibani|Orsi, Sara A|Moore, Anthony N|Dash, Pramod K
PMID: 19100245
Journal: Mol Cancer Ther. 2009 Jan;8(1):94-100.
Title: Peroxisome proliferator-activated receptor gamma agonist pioglitazone prevents the hyperglycemia caused by phosphatidylinositol 3-kinase pathway inhibition by PX-866 without affecting antitumor activity.
Author: Ihle, Nathan T|Lemos, Robert|Schwartz, David|Oh, Junghwan|Halter, Robert J|Wipf, Peter|Kirkpatrick, Lynn|Powis, Garth
PMID: 19139117
Journal: Mol Cancer Ther. 2009 Jan;8(1):194-202.
Title: Pharmacogenomic approach for the identification of novel determinants of acquired resistance to oxaliplatin in colorectal cancer.
Author: Martinez-Cardus, Anna|Martinez-Balibrea, Eva|Bandres, Eva|Malumbres, Raquel|Gines, Alba|Manzano, Jose Luis|Taron, Miquel|Garcia-Foncillas, Jesus|Abad, Albert
PMID: 19139129
Journal: Diabetes Metab Res Rev. 2009 Jan;25(1):41-9.
Title: Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells.
Author: Weinstein, Doron|Simon, Meital|Yehezkel, Einat|Laron, Zvi|Werner, Haim
PMID: 19145584
Journal: Cancer Res. 2009 Jan 15;69(2):573-82.
Title: gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Author: Meng, Raymond D|Shelton, Christopher C|Li, Yue-Ming|Qin, Li-Xuan|Notterman, Daniel|Paty, Philip B|Schwartz, Gary K
PMID: 19147571
Journal: DNA Repair (Amst). 2009 Mar 1;8(3):390-9.
Title: HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
Author: Ferrandiz, Nuria|Martin-Perez, Jorge|Blanco, Rosa|Donertas, Derya|Weber, Axel|Eilers, Martin|Dotto, Paolo|Delgado, M Dolores|Leon, Javier
PMID: 19150257
Journal: Cancer Lett. 2009 Jun 8;278(1):9-16.
Title: Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response.
Author: Alaniz, Laura|Rizzo, Miguel|Malvicini, Mariana|Jaunarena, Jorge|Avella, Diego|Atorrasagasti, Catalina|Aquino, Jorge B|Garcia, Mariana|Matar, Pablo|Silva, Marcelo|Mazzolini, Guilermo
PMID: 19185418
Journal: Clin Cancer Res. 2009 Feb 15;15(4):1297-307.
Title: Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis.
Author: Pencreach, Erwan|Guerin, Eric|Nicolet, Celine|Lelong-Rebel, Isabelle|Voegeli, Anne-Claire|Oudet, Pierre|Larsen, Annette K|Gaub, Marie-Pierre|Guenot, Dominique
PMID: 19190131
Journal: Cancer Res. 2009 Feb 15;69(4):1343-9.
Title: Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity.
Author: Song, Shumei|Mazurek, Nachman|Liu, Chunming|Sun, Yunjie|Ding, Qing Qing|Liu, Kaifeng|Hung, Mien-Chie|Bresalier, Robert S
PMID: 19190323
Journal: Cancer Invest. 2009 Mar;27(3):286-92.
Title: Chloroquine inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosis.
Author: Zheng, Yuzhu|Zhao, Ying-Lan|Deng, Xiaoqiang|Yang, Shengyong|Mao, Yongqiu|Li, Zhengguang|Jiang, Peidu|Zhao, Xia|Wei, Yuquan
PMID: 19194831
Journal: Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2835-40.
Title: Knockin of mutant PIK3CA activates multiple oncogenic pathways.
Author: Gustin, John P|Karakas, Bedri|Weiss, Michele B|Abukhdeir, Abde M|Lauring, Josh|Garay, Joseph P|Cosgrove, David|Tamaki, Akina|Konishi, Hiroyuki|Konishi, Yuko|Mohseni, Morassa|Wang, Grace|Rosen, D Marc|Denmeade, Samuel R|Higgins, Michaela J|Vitolo, Michele
PMID: 19196980
Journal: Am J Physiol Renal Physiol. 2009 Apr;296(4):F723-9.
Title: Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor.
Author: Wang, Weiwei|Reeves, W Brian|Ramesh, Ganesan
PMID: 19211685
Journal: Cancer Sci. 2009 Apr;100(4):588-94.
Title: Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice.
Author: Shiozaki, Kazuhiro|Yamaguchi, Kazunori|Sato, Ikuro|Miyagi, Taeko
PMID: 19215228
Journal: Cancer Chemother Pharmacol. 2009 Oct;64(5):953-60.
Title: Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Author: Kim, Jong Gwang|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Ryoo, Hun Mo|Bae, Sung Hwa|Kum, Yoonseop|Jeon, Seong Woo|Lim, Kyoung-Hoon|Kang, Byung-Mo|Park, In-Ja|Choi, Gyu Seog|Jun, Soo-Han
PMID: 19219602
Journal: Cancer Res. 2009 Mar 1;69(5):1851-7.
Title: PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Author: Sartore-Bianchi, Andrea|Martini, Miriam|Molinari, Francesca|Veronese, Silvio|Nichelatti, Michele|Artale, Salvatore|Di Nicolantonio, Federica|Saletti, Piercarlo|De Dosso, Sara|Mazzucchelli, Luca|Frattini, Milo|Siena, Salvatore|Bardelli, Alberto
PMID: 19223544
Journal: Strahlenther Onkol. 2009 Jan;185(1):8-18.
Title: Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Author: Niyazi, Maximilian|Marini, Patrizia|Daniel, Peter T|Humphreys, Robin|Jendrossek, Verena|Belka, Claus
PMID: 19224142
Journal: J Biol Chem. 2009 Apr 17;284(16):10912-22.
Title: Knockdown of Ron kinase inhibits mutant phosphatidylinositol 3-kinase and reduces metastasis in human colon carcinoma.
Author: Wang, Jing|Rajput, Ashwani|Kan, Julie L C|Rose, Rebecca|Liu, Xiao-Qiong|Kuropatwinski, Karen|Hauser, Jennie|Beko, Alexander|Dominquez, Ivan|Sharratt, Elizabeth A|Brattain, Lisa|Levea, Charles|Sun, Feng-Lei|Keane, David M|Gibson, Neil W|Brattain, Michael G
PMID: 19224914
Journal: J Cell Biochem. 2009 Apr 15;106(6):1113-22.
Title: Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
Author: Lee, Dae-Hee|Szczepanski, Miroslaw-Jerzy|Lee, Yong J
PMID: 19229860
Journal: J Clin Oncol. 2009 Mar 20;27(9):1477-84.
Title: PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.
Author: Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Chan, Andrew T|Engelman, Jeffrey A|Kraft, Peter|Cantley, Lewis C|Giovannucci, Edward L|Fuchs, Charles S
PMID: 19237633
Journal: J Biol Chem. 2009 Apr 17;284(16):10422-32.
Title: Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.
Author: Nemoto, Satoshi|Nakamura, Mitsuhiro|Osawa, Yosuke|Kono, Saki|Itoh, Yoshinori|Okano, Yukio|Murate, Takashi|Hara, Akira|Ueda, Hiroshi|Nozawa, Yoshinori|Banno, Yoshiko
PMID: 19240026
Journal: Int J Colorectal Dis. 2009 Jun;24(6):641-5.
Title: Protein kinase C-beta II (PKC-beta II) expression in patients with colorectal cancer.
Author: Spindler, Karen-Lise Garm|Lindebjerg, Jan|Lahn, Michael|Kjaer-Frifeldt, Sanne|Jakobsen, Anders
PMID: 19277684
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2009 Mar;29(3):416-8.
Title: [PI3K p85alpha expression and its role in the progression of colorectal cancer].
Author: Sun, Yan|Tian, Hua|Xiao, Fa-Man|Xie, Xiao-Yun|Song, Yu-Gang
PMID: 19304514
Journal: Neoplasia. 2009 Apr;11(4):355-64.
Title: Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo.
Author: van der Horst, Edward Htun|Chinn, Lawrence|Wang, Min|Velilla, Timothy|Tran, Hoang|Madrona, Yarrow|Lam, Andrew|Ji, May|Hoey, Timothy C|Sato, Aaron K
PMID: 19308290
Journal: Biochim Biophys Acta. 2009 Mar;1793(3):477-88.
Title: Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth.
Author: Ferrand, Audrey|Sandrin, Mauro S|Shulkes, Arthur|Baldwin, Graham S
PMID: 19321126
Journal: Nucl Med Biol. 2009 Apr;36(3):335-42.
Title: Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake.
Author: Monazzam, Azita|Razifar, Pasha|Ide, Susan|Rugaard Jensen, Michael|Josephsson, Raymond|Blomqvist, Carl|Langstrom, Bengt|Bergstrom, Mats
PMID: 19324279
Journal: Exp Cell Res. 2009 Jul 1;315(11):1840-9.
Title: alphavbeta5/beta6 integrin suppression leads to a stimulation of alpha2beta1 dependent cell migration resistant to PI3K/Akt inhibition.
Author: Defilles, Celine|Lissitzky, Jean-Claude|Montero, Marie-Pierre|Andre, Frederic|Prevot, Charles|Delamarre, Estelle|Marrakchi, Naziha|Luis, Jose|Rigot, Veronique
PMID: 19328197
Journal: Cancer Lett. 2009 Aug 28;281(2):213-9.
Title: Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway.
Author: Ouyang, Gaoliang|Liu, Min|Ruan, Kai|Song, Gang|Mao, Yubin|Bao, Shideng
PMID: 19328625
Journal: Anticancer Res. 2009 Jan;29(1):395-401.
Title: Curcumin synergizes the growth inhibitory properties of Indian toad (Bufo melanostictus Schneider) skin-derived factor (BM-ANF1) in HCT-116 colon cancer cells.
Author: Giri, Biplab|Gomes, Antony|Sengupta, Radha|Banerjee, Sanjeev|Nautiyal, Jyoti|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 19331178
Journal: Cancer Lett. 2009 Aug 28;281(2):162-70.
Title: Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells.
Author: Xavier, Cristina P R|Lima, Cristovao F|Preto, Ana|Seruca, Raquel|Fernandes-Ferreira, Manuel|Pereira-Wilson, Cristina
PMID: 19344998
Journal: Clin Cancer Res. 2009 Apr 15;15(8):2829-39.
Title: Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Author: Vilar, Eduardo|Mukherjee, Bhramar|Kuick, Rork|Raskin, Leon|Misek, David E|Taylor, Jeremy M G|Giordano, Thomas J|Hanash, Samir M|Fearon, Eric R|Rennert, Gad|Gruber, Stephen B
PMID: 19351759
Journal: Oncol Rep. 2009 May;21(5):1161-8.
Title: No functional and transductional significance of specific neuropilin 1 siRNA inhibition in colon carcinoma cell lines lacking VEGF receptor 2.
Author: Quante, Michael|Raskopf, Esther|Stahl, Sebastian|Vogt, Annabelle|Sauerbruch, Tilman|Schmitz, Volker
PMID: 19360289
Journal: Int J Oncol. 2009 May;34(5):1181-9.
Title: Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle.
Author: Nakamura, Junya|Aoyagi, Sayaka|Nanchi, Isamu|Nakatsuka, Shin-Ichi|Hirata, Erika|Shibata, Shohei|Fukuda, Mari|Yamamoto, Yumiko|Fukuda, Ikuyo|Tatsumi, Naoya|Ueda, Tazu|Fujiki, Fumihiro|Nomura, Masaya|Nishida, Sumiyuki|Shirakata, Toshiaki|Hosen, Naoki|Tsuboi
PMID: 19360331
Journal: Mol Cancer Ther. 2009 Apr;8(4):821-33.
Title: Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis.
Author: Kaulfuss, Silke|Burfeind, Peter|Gaedcke, Jochen|Scharf, Jens-Gerd
PMID: 19372555
Journal: Nutr Cancer. 2009;61(3):374-80.
Title: Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells.
Author: Yui, Satoko|Kanamoto, Ryuhei|Saeki, Tohru
PMID: 19373611
Journal: Head Neck. 2009 Aug;31(8):1086-94.
Title: Mechanisms of resistance to EGFR inhibitors in head and neck cancer.
Author: Cooper, Jonathan B|Cohen, Ezra Eddy Wyssam
PMID: 19378324
Journal: Int J Cancer. 2009 Sep 1;125(5):1082-91.
Title: A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene.
Author: Auyeung, Kathy K W|Cho, Chi-Hin|Ko, Joshua K S
PMID: 19384947
Journal: World J Gastroenterol. 2009 May 7;15(17):2089-96.
Title: High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells.
Author: Schimanski, Carl Christoph|Frerichs, Kirsten|Rahman, Fareed|Berger, Martin|Lang, Hauke|Galle, Peter R|Moehler, Markus|Gockel, Ines
PMID: 19418581
Journal: Cancer Lett. 2009 Sep 28;283(1):108-17.
Title: Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells.
Author: Palozza, Paola|Torelli, Cristiana|Boninsegna, Alma|Simone, Rossella|Catalano, Assunta|Mele, Maria Cristina|Picci, Nevio
PMID: 19423215
Journal: Biochem Biophys Res Commun. 2009 Jul 17;385(1):16-21.
Title: A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway.
Author: Won, Mi-Sun|Im, Namhui|Park, Soohyun|Boovanahalli, Shanthaveerappa K|Jin, Yinglan|Jin, Xuejun|Chung, Kyung-Sook|Kang, Moorim|Lee, Kiho|Park, Song-Kyu|Kim, Hwan Mook|Kwon, Byoung Mog|Lee, Jung Joon|Lee, Kyeong
PMID: 19433063
Journal: Biochem Pharmacol. 2009 Sep 15;78(6):561-72.
Title: Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.
Author: Lincova, Eva|Hampl, Ales|Pernicova, Zuzana|Starsichova, Andrea|Krcmar, Pavel|Machala, Miroslav|Kozubik, Alois|Soucek, Karel
PMID: 19433066
Journal: PLoS One. 2009 May 20;4(5):e5638.
Title: Absence of AKT1 mutations in glioblastoma.
Author: Bleeker, Fonnet E|Lamba, Simona|Zanon, Carlo|van Tilborg, Angela A|Leenstra, Sieger|Troost, Dirk|Hulsebos, Theo|Vandertop, W Peter|Bardelli, Alberto
PMID: 19461960
Journal: Arch Physiol Biochem. 2009 Jul;115(3):127-36.
Title: Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signalling in colorectal cancer cells.
Author: Seti, Hila|Leikin-Frenkel, Alicia|Werner, Haim
PMID: 19480565
Journal: Gastroenterology. 2009 Sep;137(3):914-23.
Title: Saccharomyces boulardii inhibits EGF receptor signaling and intestinal tumor growth in Apc(min) mice.
Author: Chen, Xinhua|Fruehauf, Johannes|Goldsmith, Jeffrey D|Xu, Hua|Katchar, Kianoosh K|Koon, Hon-Wai|Zhao, Dezheng|Kokkotou, Efi G|Pothoulakis, Charalabos|Kelly, Ciaran P
PMID: 19482027
Journal: Am J Gastroenterol. 2009 Jul;104(7):1790-801.
Title: High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.
Author: Uddin, Shahab|Hussain, Azhar R|Ahmed, Maqbool|Abubaker, Jehad|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Bavi, Prashant|Al-Kuraya, Khawla S
PMID: 19491830
Journal: Cancer Sci. 2009 Sep;100(9):1708-13.
Title: Knockdown of focal adhesion kinase reverses colon carcinoma multicellular resistance.
Author: Chen, Yu-Ying|Wang, Zhan-Xiang|Chang, Ping-An|Li, Jian-Jun|Pan, Feng|Yang, Li|Bian, Zhi-Heng|Zou, Lan|He, Jian-Ming|Liang, Hou-Jie
PMID: 19500106
Journal: Cancer Biol Ther. 2009 Jul;8(14):1313-7. Epub 2009 Jul 11.
Title: The signal pathways in azoxymethane-induced colon cancer and preventive implications.
Author: Chen, Jiezhong|Huang, Xu-Feng
PMID: 19502780
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title: A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author: Ogino, Shuji|Shima, Kaori|Nosho, Katsuhiko|Irahara, Natsumi|Baba, Yoshifumi|Wolpin, Brian M|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19505918
Journal: Mol Cancer Res. 2009 Jun;7(6):955-65.
Title: Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs.
Author: Martin-Fernandez, Cristina|Bales, Juliana|Hodgkinson, Cassandra|Welman, Arkadiusz|Welham, Melanie J|Dive, Caroline|Morrow, Christopher J
PMID: 19509113
Journal: Clin Cancer Res. 2009 Jun 15;15(12):4046-57.
Title: CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy.
Author: Bao, Rudi|Lai, Cheng-Jung|Qu, Hui|Wang, Dagong|Yin, Ling|Zifcak, Brian|Atoyan, Ruzanna|Wang, Jing|Samson, Maria|Forrester, Jeffrey|DellaRocca, Steven|Xu, Guang-Xin|Tao, Xu|Zhai, Hai-Xiao|Cai, Xiong|Qian, Changgeng
PMID: 19509149
Journal: Am J Gastroenterol. 2009 Aug;104(8):2047-56.
Title: A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.
Author: Ogino, Shuji|Nosho, Katsuhiko|Baba, Yoshifumi|Kure, Shoko|Shima, Kaori|Irahara, Natsumi|Toyoda, Saori|Chen, Li|Kirkner, Gregory J|Wolpin, Brian M|Chan, Andrew T|Giovannucci, Edward L|Fuchs, Charles S
PMID: 19513025
Journal: Carcinogenesis. 2009 Nov;30(11):1832-40.
Title: Leptin receptor expression in Middle Eastern colorectal cancer and its potential clinical implication.
Author: Uddin, Shahab|Bavi, Prashant P|Hussain, Azhar R|Alsbeih, Ghazi|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Ahmed, Maqbool|Al-Kuraya, Khawla S
PMID: 19520793
Journal: Obes Rev. 2009 Nov;10(6):610-6.
Title: Obesity, the PI3K/Akt signal pathway and colon cancer.
Author: Huang, X-F|Chen, J-Z
PMID: 19527447
Journal: J Chem Biol. 2009 Jun;2(2):81-7.
Title: Conditional drug screening shows that mitotic inhibitors induce AKT/PKB-insensitive apoptosis.
Author: Berndtsson, Maria|Hernlund, Emma|Shoshan, Maria C|Linder, Stig
PMID: 19568785
Journal: Cancer Sci. 2009 Oct;100(10):1801-8.
Title: DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation.
Author: Wang, Lei|Cao, Xi-Xi|Chen, Qi|Zhu, Teng-Fang|Zhu, Hong-Guang|Zheng, Li
PMID: 19572978
Journal: Int J Cancer. 2009 Nov 1;125(9):2029-35.
Title: Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers.
Author: Ikeuchi, Kyoko|Marusawa, Hiroyuki|Fujiwara, Mikio|Matsumoto, Yuko|Endo, Yoko|Watanabe, Tomohiro|Iwai, Akio|Sakai, Yoshiharu|Takahashi, Ryosuke|Chiba, Tsutomu
PMID: 19585504
Journal: Biochem Pharmacol. 2009 Nov 1;78(9):1224-32.
Title: 2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules.
Author: Li, Haitao|Wu, William Ka Kei|Zheng, Zongping|Che, Chun Tao|Yu, Le|Li, Zhi Jie|Wu, Ya Chun|Cheng, Ka-Wing|Yu, Jun|Cho, Chi Hin|Wang, Mingfu
PMID: 19591809
Journal: Anticancer Res. 2009 Jul;29(7):2473-8.
Title: Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells.
Author: Doan, Hung Q|Bowen, Kanika A|Jackson, Lindsey A|Evers, B Mark
PMID: 19596916
Journal: Biochem Biophys Res Commun. 2009 Sep 25;387(3):521-4.
Title: Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells.
Author: Jiang, Xiaohua|Sinnett-Smith, James|Rozengurt, Enrique
PMID: 19615971
Journal: Carcinogenesis. 2009 Oct;30(10):1796-804.
Title: HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells.
Author: Moore, Amy E|Greenhough, Alexander|Roberts, Heather R|Hicks, Diane J|Patsos, Helena A|Williams, Ann C|Paraskeva, Christos
PMID: 19638428
Journal: Oncol Rep. 2009 Sep;22(3):525-34.
Title: Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion.
Author: Kang, Myoung Hee|Kang, Han Na|Kim, Jung Lim|Kim, Jun Suk|Oh, Sang Cheul|Yoo, Young A
PMID: 19639199
Journal: Anticancer Res. 2009 Aug;29(8):2987-91.
Title: LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells.
Author: Liu, Jian-Jun|Duan, Rui-Dong
PMID: 19661305
Journal: Anticancer Res. 2009 Aug;29(8):3185-90.
Title: Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.
Author: Johnson, Sara M|Gulhati, Pat|Arrieta, Isela|Wang, Xiaofu|Uchida, Tatsuo|Gao, Tianyan|Evers, B Mark
PMID: 19661333
Journal: Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title: Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author: Meriggi, F|Di Biasi, B|Abeni, C|Zaniboni, A
PMID: 19663767
Journal: Clin Cancer Res. 2009 Sep 1;15(17):5414-25.
Title: 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Author: Shin, Sung-Won|Seo, Chi-Yeon|Han, Hoon|Han, Jin-Yeong|Jeong, Jin-Sook|Kwak, Jong-Young|Park, Joo-In
PMID: 19690198
Journal: J Clin Invest. 2009 Sep;119(9):2702-13.
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Author: Lee, Daekee|Yu, Ming|Lee, Eunjung|Kim, Hyunok|Yang, Yanan|Kim, Kyoungmi|Pannicia, Christina|Kurie, Jonathan M|Threadgill, David W
PMID: 19690388
Journal: Carcinogenesis. 2009 Oct;30(10):1670-7.
Title: Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
Author: Calleros, Laura|Sanchez-Hernandez, Irene|Baquero, Pablo|Toro, Maria Jose|Chiloeches, Antonio
PMID: 19700418
Journal: Mol Cancer Ther. 2009 Sep;8(9):2566-74.
Title: Prostate-derived factor--a novel inhibitor of drug-induced cell death in colon cancer cells.
Author: Proutski, Irina|Stevenson, Leanne|Allen, Wendy L|McCulla, Andrea|Boyer, John|McLean, Estelle G|Longley, Daniel B|Johnston, Patrick G
PMID: 19723892
Journal: Biomed Environ Sci. 2009 Jun;22(3):244-52.
Title: Role of prosurvival molecules in the action of lidamycin toward human tumor cells.
Author: Yang, A-Jing|Shi, Wei-Wei|Li, Yong|Wang, Zhen|Shao, Rong-Guang|Li, Dian-Dong|He, Qi-Yang
PMID: 19725468
Journal: Radiother Oncol. 2009 Sep;92(3):371-8.
Title: 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226.
Author: Hehlgans, Stephanie|Lange, Inga|Eke, Iris|Cordes, Nils
PMID: 19729215
Journal: Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):534-42.
Title: Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.
Author: Sandur, Santosh K|Deorukhkar, Amit|Pandey, Manoj K|Pabon, Ana Maria|Shentu, Shujun|Guha, Sushovan|Aggarwal, Bharat B|Krishnan, Sunil
PMID: 19735878
Journal: Sci Signal. 2009 Sep 15;2(88):ra54.
Title: Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.
Author: Gianni, Davide|Diaz, Begona|Taulet, Nicolas|Fowler, Bruce|Courtneidge, Sara A|Bokoch, Gary M
PMID: 19755710
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Jul;40(4):644-6, 654.
Title: [The relationship between PTEN expression and PI3K/AKT signal pathway in colon carcinoma].
Author: Qi, Jian-Kang|Huang, Xiao-Li|Meng, Zhang-Ming|Gan, Hua-Tian|Fu, Dai-Gang
PMID: 19764563
Journal: Oncogene. 2009 Dec 17;28(50):4421-33.
Title: A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
Author: Mamidipudi, V|Cartwright, C A
PMID: 19767770
Journal: World J Gastroenterol. 2009 Sep 28;15(36):4547-55.
Title: Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action.
Author: Sun, Hong|Ren, Juan|Zhu, Qing|Kong, Fan-Zhong|Wu, Lei|Pan, Bo-Rong
PMID: 19777613
Journal: Cancer Microenviron. 2009 Sep 25;2(1):69-80.
Title: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta.
Author: Kaler, Pawan|Godasi, Bramara N|Augenlicht, Leonard|Klampfer, Lidija
PMID: 19779850
Journal: Int J Oncol. 2009 Nov;35(5):1037-43.
Title: Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention.
Author: Guruswamy, Suresh|Rao, Chinthalapally V
PMID: 19787257
Journal: IUBMB Life. 2009 Oct;61(10):1001-9.
Title: Aquaporin-1 activity of plasma membrane affects HT20 colon cancer cell migration.
Author: Jiang, Yong
PMID: 19787701
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title: Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author: Kure, Shoko|Nosho, Katsuhiko|Baba, Yoshifumi|Irahara, Natsumi|Shima, Kaori|Ng, Kimmie|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19789368
Journal: Mol Cell Biol. 2009 Dec;29(23):6192-205.
Title: beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.
Author: Li, Xin|Liu, Jianyu|Gao, Tianyan
PMID: 19797085
Journal: Digestion. 2009;80(4):215-25.
Title: Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer.
Author: Yonezawa, Masaoki|Wada, Ken|Tatsuguchi, Atsushi|Akamatsu, Tomonori|Gudis, Katya|Seo, Tsuguhiko|Mitsui, Keigo|Nagata, Kazuhiro|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu
PMID: 19797898
Journal: Biol Pharm Bull. 2009 Oct;32(10):1760-4.
Title: Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells.
Author: Hyun, Jae-Hee|Kim, Sang-Cheol|Kang, Jung-Il|Kim, Min-Kyoung|Boo, Hye-Jin|Kwon, Jung-Mi|Koh, Young-Sang|Hyun, Jin-Won|Park, Deok-Bae|Yoo, Eun-Sook|Kang, Hee-Kyoung
PMID: 19801840
Journal: Nutr Cancer. 2009;61(4):564-71.
Title: Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway.
Author: Xavier, Cristina P R|Lima, Cristovao F|Fernandes-Ferreira, Manuel|Pereira-Wilson, Cristina
PMID: 19838929
Journal: J Med Food. 2009 Oct;12(5):952-8.
Title: trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis.
Author: Cho, Han Jin|Kwon, Gyoo Taik|Park, Jung Han Yoon
PMID: 19857056
Journal: Int J Oncol. 2009 Dec;35(6):1499-504.
Title: Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK.
Author: Shin, Dong Yeok|Lee, Won Sup|Lu, Jing Nan|Kang, Myung Hee|Ryu, Chung Ho|Kim, Gi Young|Kang, Ho Sung|Shin, Sung Chul|Choi, Yung Hyun
PMID: 19885574
Journal: Mol Cancer. 2009 Nov 12;8:100.
Title: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Author: Nakamura, Yoshitaka|Yogosawa, Shingo|Izutani, Yasuyuki|Watanabe, Hirotsuna|Otsuji, Eigo|Sakai, Tosiyuki
PMID: 19909554
Journal: Clin Transl Oncol. 2009 Nov;11(11):737-47.
Title: Biomarkers and anti-EGFR therapies for KRAS wild-type metastatic colorectal cancer.
Author: Garcia-Saenz, Jose A|Sastre, Javier|Diaz-Rubio Garcia, Eduardo
PMID: 19917537
Journal: Clin Cancer Res. 2009 Dec 1;15(23):7207-16.
Title: Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.
Author: Gulhati, Pat|Cai, Qingsong|Li, Jing|Liu, Jianyu|Rychahou, Piotr G|Qiu, Suimin|Lee, Eun Y|Silva, Scott R|Bowen, Kanika A|Gao, Tianyan|Evers, B Mark
PMID: 19934294
Journal: Cancer Res. 2009 Dec 15;69(24):9457-64.
Title: Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis.
Author: Fyrst, Henrik|Oskouian, Babak|Bandhuvula, Padmavathi|Gong, Yaqiong|Byun, Hoe Sup|Bittman, Robert|Lee, Andrew R|Saba, Julie D
PMID: 19934323
Journal: Transl Oncol. 2009 Dec;2(4):281-90.
Title: Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells.
Author: Tureckova, Jolana|Vojtechova, Martina|Krausova, Michaela|Sloncova, Eva|Korinek, Vladimir
PMID: 19956390
Journal: Cancer Cell. 2009 Dec 8;16(6):463-74.
Title: Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation.
Author: Jaiswal, Bijay S|Janakiraman, Vasantharajan|Kljavin, Noelyn M|Chaudhuri, Subhra|Stern, Howard M|Wang, Weiru|Kan, Zhengyan|Dbouk, Hashem A|Peters, Brock A|Waring, Paul|Dela Vega, Trisha|Kenski, Denise M|Bowman, Krista K|Lorenzo, Maria|Li, Hong|Wu, Jianshen
PMID: 19962665
Journal: BMC Cancer. 2009 Dec 12;9:435.
Title: Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway.
Author: Tseng, Ya-Shih|Lee, Jenq-Chang|Huang, Chi-Ying F|Liu, Hsiao-Sheng
PMID: 20003375
Journal: Zhonghua Zhong Liu Za Zhi. 2009 Oct;31(10):746-851.
Title: [Combination with SN-38 on human colon cancer LoVo cells].
Author: Wang, Yan|Xu, Jian-ming|Xu, Qin-zhi|Zhou, Ping-kun|Song, San-tai
PMID: 20021826
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2009 Nov;40(6):1021-3, 1052.
Title: [Change from inflammation to carcinoma in ulcerative colitis: the role of PTEN/PI3K/AKT].
Author: Fu, Dai-Gang|Huang, Xiao-Li|Gan, Hua-Tian|Zhang, De-Kui|Zhao, Li-Qiang
PMID: 20067111
Journal: Oncology. 2009;77 Suppl 1:69-74.
Title: The dark side of the moon: the PI3K/PTEN/AKT pathway in colorectal carcinoma.
Author: Silvestris, Nicola|Tommasi, Stefania|Petriella, Daniela|Santini, Daniele|Fistola, Ettore|Russo, Antonio|Numico, Gianmauro|Tonini, Giuseppe|Maiello, Evaristo|Colucci, Giuseppe
PMID: 20130434
Journal: An R Acad Nac Med (Madr). 2009;126(2):243-57; discussion 258-62.
Title: [Biomarkers and anti-EGFR therapies for KRAS wild-type tumors in metastatic colorectal cancer patients].
Author: Diaz-Rubio Garcia, Eduardo
PMID: 20432670
Journal: Mol Med Rep. 2009 May-Jun;2(3):497-502.
Title: Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells.
Author: Lim, Soo-Jeong|Choi, Moon-Kyung|Kim, Min Jung|Lee, Chang-Hun
PMID: 21475856
Journal: J Cell Mol Med. 2010 Mar;14(3):636-46.
Title: A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo.
Author: Laladhas, Krishna P|Cheriyan, Vino T|Puliappadamba, Vineshkumar T|Bava, Smitha V|Unnithan, Rajesh G|Vijayammal, Parvathy L|Anto, Ruby John
PMID: 19183244
Journal: Int J Cancer. 2010 Feb 1;126(3):756-63.
Title: Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice.
Author: Asp, Michelle L|Tian, Min|Wendel, Angela A|Belury, Martha A
PMID: 19634137
Journal: Fam Cancer. 2010 Jun;9(2):125-9.
Title: Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.
Author: Ekstrand, Anna Isinger|Jonsson, Mats|Lindblom, Annika|Borg, Ake|Nilbert, Mef
PMID: 19731079
Journal: Gastroenterology. 2010 Jan;138(1):241-54.
Title: The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Author: Lin, Jieru Egeria|Li, Peng|Snook, Adam Eugene|Schulz, Stephanie|Dasgupta, Abhijit|Hyslop, Terry Marie|Gibbons, Ahmara Vivian|Marszlowicz, Glen|Pitari, Giovanni Mario|Waldman, Scott Arthur
PMID: 19737566
Journal: Hum Pathol. 2010 Jan;41(1):59-69.
Title: The role of Reg IV gene and its encoding product in gastric carcinogenesis.
Author: Zheng, Hua-Chuan|Xu, Xiao-Yan|Yu, Miao|Takahashi, Hiroyuki|Masuda, Shinji|Takano, Yasuo
PMID: 19740514
Journal: J Cell Mol Med. 2010 Jun;14(6B):1520-31.
Title: Translational up-regulation of Aurora-A in EGFR-overexpressed cancer.
Author: Lai, Chien-Hsien|Tseng, Joseph T|Lee, Yi-Chao|Chen, Ying-Ju|Lee, Jeng-Chang|Lin, Bo-Wen|Huang, Tai-Chien|Liu, Yao-Wen|Leu, Tzeng-Horng|Liu, Yi-Wen|Chen, Ya-Ping|Chang, Wen-Chang|Hung, Liang-Yi
PMID: 19799648
Journal: Int J Cancer. 2010 Jun 15;126(12):2847-57.
Title: A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism.
Author: Bertrand, Claudine|Kowalski-Chauvel, Aline|Do, Catherine|Resa, Cecile|Najib, Souad|Daulhac, Laurence|Wang, Timothy C|Ferrand, Audrey|Seva, Catherine
PMID: 19876923
Journal: Cancer Sci. 2010 Feb;101(2):440-7.
Title: Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines.
Author: Bijnsdorp, Irene V|Kruyt, Frank A E|Fukushima, Masakazu|Smid, Kees|Gokoel, Shanti|Peters, Godefridus J
PMID: 19886911
Journal: Ann Oncol. 2010 May;21(5):1020-6.
Title: A window of opportunity phase II study of enzastaurin in chemonaive patients with asymptomatic metastatic colorectal cancer.
Author: Glimelius, B|Lahn, M|Gawande, S|Cleverly, A|Darstein, C|Musib, L|Liu, Y|Spindler, K L|Frodin, J-E|Berglund, A|Bystrom, P|Qvortrup, C|Jakobsen, A|Pfeiffer, P
PMID: 19901015
Journal: Int J Cancer. 2010 Jul 1;127(1):195-206.
Title: The effect of focal adhesion kinase gene silencing on 5-fluorouracil chemosensitivity involves an Akt/NF-kappaB signaling pathway in colorectal carcinomas.
Author: Chen, Yuying|Wang, Zhanxiang|Chang, Pingan|Xiang, Liuxin|Pan, Feng|Li, Jianjun|Jiang, Jinyan|Zou, Lan|Yang, Li|Bian, Zhiheng|Liang, Houjie
PMID: 19904749
Journal: Mol Carcinog. 2010 Mar;49(3):235-46.
Title: The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells.
Author: Yan, Kun-Huang|Yao, Chih-Jung|Chang, Hwan-You|Lai, Gi-Ming|Cheng, Ann-Lii|Chuang, Shuang-En
PMID: 19908241
Journal: Cancer Chemother Pharmacol. 2010 Aug;66(3):547-58.
Title: Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.
Author: Nannizzi, Sara|Veal, Gareth J|Giovannetti, Elisa|Mey, Valentina|Ricciardi, Simona|Ottley, Christopher J|Del Tacca, Mario|Danesi, Romano
PMID: 20020129
Journal: Int J Oncol. 2010 Feb;36(2):427-34.
Title: A kelch family protein Nd1-L functions as a metastasis suppressor in cancer cells via Rho family proteins mediated mechanism.
Author: Ohta, Yoshihito|Fujimura, Lisa|Nishio, Saori|Arima, Masafumi|Sakamoto, Akemi|Shimada, Hideaki|Ochiai, Takenori|Tokuhisa, Takeshi|Hatano, Masahiko
PMID: 20043078
Journal: Int J Cancer. 2010 Sep 1;127(6):1321-31.
Title: Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer.
Author: Perkins, Geraldine|Lievre, Astrid|Ramacci, Carole|Meatchi, Tchao|de Reynies, Aurelien|Emile, Jean-Francois|Boige, Valerie|Tomasic, Gorana|Bachet, Jean-Baptiste|Bibeau, Frederic|Bouche, Olivier|Penault-Llorca, Frederique|Merlin, Jean-Louis|Laurent-Puig, Pi
PMID: 20049837
Journal: Mol Cancer Ther. 2010 Jan;9(1):202-10.
Title: Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.
Author: Koduru, Srinivas|Kumar, Raj|Srinivasan, Sowmyalakshmi|Evers, Mark B|Damodaran, Chendil
PMID: 20053782
Journal: Cancer Lett. 2010 Jul 1;293(1):23-30.
Title: Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
Author: Choi, Sujin|Choi, Yunjin|Dat, Nguyen Tien|Hwangbo, Cheol|Lee, Jung Joon|Lee, Jeong-Hyung
PMID: 20056314
Journal: Biochem Biophys Res Commun. 2010 Feb 5;392(2):190-5.
Title: A novel histone deacetylase inhibitor Chidamide induces apoptosis of human colon cancer cells.
Author: Liu, Lin|Chen, Baoan|Qin, Shukui|Li, Suyi|He, Xiangming|Qiu, Shaomin|Zhao, Wei|Zhao, Hong
PMID: 20060381
Journal: PLoS One. 2010 Jan 13;5(1):e8507.
Title: Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions.
Author: Becker, Susann|Wandel, Elke|Wobus, Manja|Schneider, Rick|Amasheh, Salah|Sittig, Doreen|Kerner, Christiane|Naumann, Ronald|Hamann, Joerg|Aust, Gabriela
PMID: 20084281
Journal: J Pathol. 2010 Apr;220(5):542-50.
Title: K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.
Author: Luo, Feijun|Ye, Hongtao|Hamoudi, Rifat|Dong, Gehong|Zhang, Wenyan|Patek, Charles E|Poulogiannis, George|Arends, Mark J
PMID: 20087880
Journal: Curr Cancer Drug Targets. 2010 Feb;10(1):68-79.
Title: Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients.
Author: Ruzzo, Annamaria|Graziano, Francesco|Canestrari, Emanuele|Magnani, Mauro
PMID: 20088793
Journal: Carcinogenesis. 2010 Apr;31(4):597-606.
Title: TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Author: Kim, Semi|Kang, Hee Young|Nam, Eun-Hee|Choi, Myung-Sook|Zhao, Xue-Feng|Hong, Chang Soo|Lee, Jung Weon|Lee, Jae Hyuk|Park, Young-Kyu
PMID: 20118200
Journal: Int J Oncol. 2010 Mar;36(3):585-92.
Title: Rho-kinase regulates negatively the epidermal growth factor-stimulated colon cancer cell proliferation.
Author: Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kozawa, Osamu|Moriwaki, Hisataka
PMID: 20126978
Journal: Int J Oncol. 2010 Mar;36(3):689-98.
Title: REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells.
Author: Rafa, Louisa|Dessein, Anne-Frederique|Devisme, Louise|Buob, David|Truant, Stephanie|Porchet, Nicole|Huet, Guillemette|Buisine, Marie-Pierre|Lesuffleur, Thecla
PMID: 20126989
Journal: Oncol Rep. 2010 Mar;23(3):757-61.
Title: Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation.
Author: Lee, Minyoung|Park, Jung-Jin|Lee, Yun-Sil
PMID: 20127017
Journal: Oncologist. 2010;15(2):157-67.
Title: Predicting response to EGFR inhibitors in metastatic colorectal cancer: current practice and future directions.
Author: Shankaran, Veena|Obel, Jennifer|Benson, Al B 3rd
PMID: 20133499
Journal: Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2598-603.
Title: Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Author: Ericson, Kajsa|Gan, Christine|Cheong, Ian|Rago, Carlo|Samuels, Yardena|Velculescu, Victor E|Kinzler, Kenneth W|Huso, David L|Vogelstein, Bert|Papadopoulos, Nickolas
PMID: 20133737
Journal: Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7.
Title: Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.
Author: Zhao, Yiqing|Zhang, Xiaodong|Guda, Kishore|Lawrence, Earl|Sun, Qun|Watanabe, Toshio|Iwakura, Yoichiro|Asano, Masahide|Wei, Lanlan|Yang, Zhirong|Zheng, Weiping|Dawson, Dawn|Willis, Joseph|Markowitz, Sanford D|Satake, Masanobu|Wang, Zhenghe
PMID: 20133777
Journal: Bioorg Med Chem Lett. 2010 Mar 15;20(6):2038-43.
Title: Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer.
Author: Desai, Dhimant|Madhunapantula, SubbaRao V|Gowdahalli, Krishnegowda|Sharma, Arati|Chandagaludoreswamy, Raghavendragowda|El-Bayoumy, Karam|Robertson, Gavin P|Amin, Shantu
PMID: 20153642
Journal: Carcinogenesis. 2010 Jun;31(6):1092-9.
Title: Suppression of mTOR via Akt-dependent and -independent mechanisms in selenium-treated colon cancer cells: involvement of AMPKalpha1.
Author: Lee, Yun-Kyoung|Park, Song Yi|Kim, Young-Min|Kim, Dong Chool|Lee, Won Sup|Surh, Young-Joon|Park, Ock Jin
PMID: 20164123
Journal: Histol Histopathol. 2010 Apr;25(4):473-84.
Title: REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study.
Author: Li, Xiao-Han|Zheng, Yang|Zheng, Hua-Chuan|Takahashi, Hiroyuki|Yang, Xiang-Hong|Masuda, Shinji|Takano, Yasuo
PMID: 20183800
Journal: Cell Biol Int. 2010 Apr 14;34(6):565-72.
Title: Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21.
Author: Cai, Wen-Jie|Wang, Ming-Jie|Ju, Li-Hua|Wang, Cheng|Zhu, Yi-Chun
PMID: 20184555
Journal: Biochim Biophys Acta. 2010 Aug;1806(1):66-73.
Title: Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK.
Author: Brauer, Patrick M|Tyner, Angela L
PMID: 20193745
Journal: Mol Cancer Res. 2010 Mar;8(3):421-32.
Title: 3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway.
Author: Lu, Zhuomei|Cox-Hipkin, Mary Ann|Windsor, William T|Boyapati, Anita
PMID: 20197379
Journal: Int J Oncol. 2010 Apr;36(4):941-53.
Title: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
Author: Lee, Hwa Young|Crawley, Suzanne|Hokari, Ryota|Kwon, Sungwon|Kim, Young S
PMID: 20198339
Journal: Int J Oncol. 2010 Apr;36(4):1007-13.
Title: Differential effects of resveratrol and novel resveratrol derivative, HS-1793, on endoplasmic reticulum stress-mediated apoptosis and Akt inactivation.
Author: Um, Hee Jung|Bae, Jae Hoon|Park, Jong-Wook|Suh, Hongsuk|Jeong, Na Young|Yoo, Young Hyun|Kwon, Taeg Kyu
PMID: 20198347
Journal: J Cancer Res Clin Oncol. 2010 Nov;136(11):1773-82.
Title: PI3K/Akt and GSK-3beta prevents in a differential fashion the malignant phenotype of colorectal cancer cells.
Author: de Araujo, Wallace Martins|Vidal, Flavia Castello Branco|de Souza, Waldemir Fernandes|de Freitas, Julio Cesar Madureira Jr|de Souza, Wanderley|Morgado-Diaz, Jose Andres
PMID: 20204404
Journal: Biochem Biophys Res Commun. 2010 Apr 9;394(3):774-9.
Title: Rosiglitazone enhances the radiosensitivity of p53-mutant HT-29 human colorectal cancer cells.
Author: Chiu, Shu-Jun|Hsaio, Ching-Hui|Tseng, Ho-Hsing|Su, Yu-Han|Shih, Wen-Ling|Lee, Jeng-Woei|Chuah, Jennifer Qiu-Yu
PMID: 20227390
Journal: Endocr Relat Cancer. 2010 Jun 1;17(2):351-60.
Title: Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.
Author: Algire, Carolyn|Amrein, Lilian|Zakikhani, Mahvash|Panasci, Lawrence|Pollak, Michael
PMID: 20228137
Journal: BMC Cancer. 2010 Mar 16;10:101.
Title: A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
Author: Fumagalli, Debora|Gavin, Patrick G|Taniyama, Yusuke|Kim, Seung-Il|Choi, Hyun-Joo|Paik, Soonmyung|Pogue-Geile, Katherine L
PMID: 20233444
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77.
Title: Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B.
Author: Rafiee, Parvaneh|Binion, David G|Wellner, Michael|Behmaram, Behnaz|Floer, Martin|Mitton, Elizabeth|Nie, Linghui|Zhang, Zhihong|Otterson, Mary F
PMID: 20299603
Journal: Anticancer Res. 2010 Feb;30(2):319-25.
Title: Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
Author: Patel, Bhaumik B|Gupta, Deepshika|Elliott, Althea A|Sengupta, Vivek|Yu, Yingjie|Majumdar, Adhip P N
PMID: 20332435
Journal: Chem Biol Interact. 2010 May 14;185(3):247-52.
Title: (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
Author: Shimizu, Masahito|Shirakami, Yohei|Sakai, Hiroyasu|Yasuda, Yoichi|Kubota, Masaya|Adachi, Seiji|Tsurumi, Hisashi|Hara, Yukihiko|Moriwaki, Hisataka
PMID: 20346928
Journal: Mol Cancer Ther. 2010 Apr;9(4):813-24.
Title: Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells.
Author: Ramana, Kota V|Tammali, Ravinder|Srivastava, Satish K
PMID: 20354121
Journal: Mol Med. 2010 Jul-Aug;16(7-8):271-7.
Title: Upregulation of SPRR3 promotes colorectal tumorigenesis.
Author: Cho, Dong-Hyung|Jo, Yoon Kyung|Roh, Seon Ae|Na, Young-Soon|Kim, Tae Won|Jang, Se Jin|Kim, Yong Sung|Kim, Jin Cheon
PMID: 20379613
Journal: Anticancer Res. 2010 Mar;30(3):785-92.
Title: Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
Author: Gao, Xiaohua|Deeb, Dorrah|Hao, Jiang|Liu, Yongbo|Arbab, Ali S|Dulchavsky, Scott A|Gautam, Subhash C
PMID: 20392997
Journal: Anticancer Res. 2010 Mar;30(3):799-804.
Title: Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin.
Author: Abdelnour-Berchtold, Etienne|Cerantola, Yannick|Roulin, Didier|Dormond-Meuwly, Anne|Demartines, Nicolas|Dormond, Olivier
PMID: 20392999
Journal: Int J Colorectal Dis. 2010 Jul;25(7):795-804.
Title: Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib.
Author: Voutsadakis, Ioannis A|Patrikidou, Anna|Tsapakidis, Konstantinos|Karagiannaki, Aristea|Hatzidaki, Eleana|Stathakis, Nikolaos E|Papandreou, Christos N
PMID: 20397022
Journal: Mol Cancer Ther. 2010 May;9(5):1308-17.
Title: Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Author: Serova, Maria|Astorgues-Xerri, Lucile|Bieche, Ivan|Albert, Sebastien|Vidaud, Michel|Benhadji, Karim A|Emami, Shahin|Vidaud, Dominique|Hammel, Pascal|Theou-Anton, Nathalie|Gespach, Christian|Faivre, Sandrine|Raymond, Eric
PMID: 20406951
Journal: Cancer Res. 2010 May 1;70(9):3677-86.
Title: Molecular target class is predictive of in vitro response profile.
Author: Greshock, Joel|Bachman, Kurtis E|Degenhardt, Yan Y|Jing, Junping|Wen, Yuan H|Eastman, Stephen|McNeil, Elizabeth|Moy, Christopher|Wegrzyn, Ronald|Auger, Kurt|Hardwicke, Mary Ann|Wooster, Richard
PMID: 20406975
Journal: Gastroenterology. 2010 Aug;139(2):574-85.
Title: Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Author: Xiao, Hui|Yin, Weiguo|Khan, Mohammed A|Gulen, Muhammet F|Zhou, Hang|Sham, Ho Pan|Jacobson, Kevan|Vallance, Bruce A|Li, Xiaoxia
PMID: 20416302
Journal: J Am Coll Surg. 2010 May;210(5):767-76, 776-8.
Title: Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.
Author: Johnson, Sara M|Gulhati, Pat|Rampy, Bill A|Han, Yimei|Rychahou, Piotr G|Doan, Hung Q|Weiss, Heidi L|Evers, B Mark
PMID: 20421047
Journal: Mol Cancer. 2010 Apr 30;9:98.
Title: Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.
Author: Wang, Bi-Dar|Kline, Christina Leah B|Pastor, Danielle M|Olson, Thomas L|Frank, Bryan|Luu, Truong|Sharma, Arun K|Robertson, Gavin|Weirauch, Matthew T|Patierno, Steven R|Stuart, Joshua M|Irby, Rosalyn B|Lee, Norman H
PMID: 20433755
Journal: Clin Lung Cancer. 2010 May;11(3):169-75.
Title: Protein kinase C-beta gene variants, pathway activation, and enzastaurin activity in lung cancer.
Author: Lee, Sang-Haak|Chen, Tingan|Zhou, Jun|Hofmann, Jennifer|Bepler, Gerold
PMID: 20439192
Journal: Mol Cell Biochem. 2010 Sep;342(1-2):63-70.
Title: 17beta-estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells.
Author: Lai, Tung-Yuan|Chen, Li-Mien|Lin, Jing-Ying|Tzang, Bor-Show|Lin, James A|Tsai, Chang-Hai|Lin, Yueh-Min|Huang, Chih-Yang|Liu, Chung-Jung|Hsu, Hsi-Hsien
PMID: 20446020
Journal: Mol Biol Cell. 2010 Jul 1;21(13):2338-54.
Title: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
Author: Ghosh, Pradipta|Beas, Anthony O|Bornheimer, Scott J|Garcia-Marcos, Mikel|Forry, Erin P|Johannson, Carola|Ear, Jason|Jung, Barbara H|Cabrera, Betty|Carethers, John M|Farquhar, Marilyn G
PMID: 20462955
Journal: Cancer Sci. 2010 Aug;101(8):1861-5.
Title: Fatty acid synthase inhibitor cerulenin suppresses liver metastasis of colon cancer in mice.
Author: Murata, Soichiro|Yanagisawa, Kazuhiko|Fukunaga, Kiyoshi|Oda, Tatsuya|Kobayashi, Akihiko|Sasaki, Ryoko|Ohkohchi, Nobuhiro
PMID: 20491775
Journal: J Cell Biochem. 2010 Oct 1;111(2):412-24.
Title: Sodium 5,6-benzylidene-L-ascorbate induces oxidative stress, autophagy, and growth arrest in human colon cancer HT-29 cells.
Author: Cheung, F W K|Che, C T|Sakagami, H|Kochi, M|Liu, W K
PMID: 20503249
Journal: BMC Cancer. 2010 May 26;10:238.
Title: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways.
Author: Vanamala, Jairam|Reddivari, Lavanya|Radhakrishnan, Sridhar|Tarver, Chris
PMID: 20504360
Journal: Tumour Biol. 2010 Oct;31(5):427-36.
Title: The role of NF-kappaB and PPARgamma in experimentally induced colorectal cancer and chemoprevention by cyclooxygenase-2 inhibitors.
Author: Vaish, Vivek|Tanwar, Lalita|Sanyal, Sankar Nath
PMID: 20514536
Journal: Cancer J. 2010 May-Jun;16(3):196-201.
Title: Biology of colorectal cancer.
Author: Saif, Muhammad Wasif|Chu, Edward
PMID: 20526096
Journal: J Biol Chem. 2010 Aug 6;285(32):24987-98.
Title: Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1.
Author: Larson, Yan|Liu, Jianyu|Stevens, Payton D|Li, Xin|Li, Jing|Evers, B Mark|Gao, Tianyan
PMID: 20530489
Journal: Carcinogenesis. 2010 Aug;31(8):1376-80.
Title: Activation of Akt and MAPK pathways enhances the tumorigenicity of CD133+ primary colon cancer cells.
Author: Wang, Y K|Zhu, Y L|Qiu, F M|Zhang, T|Chen, Z G|Zheng, S|Huang, J
PMID: 20530554
Journal: PLoS One. 2010 Jun 4;5(6):e10966.
Title: Hypoxia activates the K-ras proto-oncogene to stimulate angiogenesis and inhibit apoptosis in colon cancer cells.
Author: Zeng, Min|Kikuchi, Hirotoshi|Pino, Maria S|Chung, Daniel C
PMID: 20532039
Journal: Radiat Environ Biophys. 2010 Aug;49(3):427-35.
Title: Tumor cell migration is not influenced by p21 in colon carcinoma cell lines after irradiation with X-ray or (12)C heavy ions.
Author: Goetze, Kristina|Scholz, Michael|Taucher-Scholz, Gisela|Mueller-Klieser, Wolfgang
PMID: 20535615
Journal: Planta Med. 2010 Nov;76(16):1827-33.
Title: Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity.
Author: Chao, Hsueh-Ping|Kuo, Cheng-Deng|Chiu, Jen-Hwey|Fu, Shu-Ling
PMID: 20539971
Journal: BMC Cancer. 2010 Jun 14;10:287.
Title: Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations.
Author: Krech, Till|Thiede, Margarethe|Hilgenberg, Ellen|Schafer, Reinhold|Jurchott, Karsten
PMID: 20546605
Journal: J Biol Chem. 2010 Aug 13;285(33):25458-66.
Title: Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Author: Chen, Jinn-Shiun|Hsu, Yuan-Ming|Chen, Chia-Chi|Chen, Li-Li|Lee, Chun-Chung|Huang, Tze-Sing
PMID: 20558745
Journal: Neoplasia. 2010 Jun;12(6):443-52.
Title: Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.
Author: van Houdt, Winan J|Hoogwater, Frederik J H|de Bruijn, Menno T|Emmink, Benjamin L|Nijkamp, Maarten W|Raats, Danielle A E|van der Groep, Petra|van Diest, Paul|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 20563247
Journal: FASEB J. 2010 Nov;24(11):4291-301.
Title: Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells.
Author: Ricci-Vitiani, Lucia|Mollinari, Cristiana|di Martino, Simona|Biffoni, Mauro|Pilozzi, Emanuela|Pagliuca, Alfredo|de Stefano, Maria Chiara|Circo, Rita|Merlo, Daniela|De Maria, Ruggero|Garaci, Enrico
PMID: 20566622
Journal: Tumour Biol. 2010 Dec;31(6):575-82.
Title: p21-activated kinase 5 inhibits camptothecin-induced apoptosis in colorectal carcinoma cells.
Author: Wang, Xia|Gong, Wei|Qing, Haitao|Geng, Yan|Wang, Xinying|Zhang, Yongsheng|Peng, Liang|Zhang, Hongquan|Jiang, Bo
PMID: 20567954
Journal: Arch Toxicol. 2010 Sep;84(9):731-40.
Title: EP4 upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells.
Author: Wu, Cheng-Hsun|Shih, Yuan-Wei|Chang, Chun-Hua|Ou, Ting-Tsz|Huang, Chi-Chou|Hsu, Jeng-Dong|Wang, Chau-Jong
PMID: 20571779
Journal: Gastroenterology. 2010 Sep;139(3):869-81, 881.e1-9.
Title: Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.
Author: Lee, Goo|Goretsky, Tatiana|Managlia, Elizabeth|Dirisina, Ramanarao|Singh, Ajay Pal|Brown, Jeffrey B|May, Randal|Yang, Guang-Yu|Ragheb, Josette William|Evers, B Mark|Weber, Christopher R|Turner, Jerrold R|He, Xi C|Katzman, Rebecca B|Li, Linheng|Barrett, Te
PMID: 20580720
Journal: Br J Pharmacol. 2010 Jul;160(6):1352-61.
Title: 2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice.
Author: Li, Haitao|Wu, William Ka Kei|Li, Zhi Jie|Chan, Kam Ming|Wong, Clover Ching Man|Ye, Cai Guo|Yu, Le|Sung, Joseph Jao Yiu|Cho, Chi Hin|Wang, Mingfu
PMID: 20590626
Journal: Biochim Biophys Acta. 2010 Sep;1803(9):1106-13.
Title: P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
Author: Huynh, Nhi|Liu, Kevin H|Baldwin, Graham S|He, Hong
PMID: 20595063
Journal: Int J Oncol. 2010 Aug;37(2):473-82.
Title: Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells.
Author: Li, Zhuzhu|Yao, Hangping|Guin, Sunny|Padhye, Snehal S|Zhou, Yong-Qing|Wang, Ming-Hai
PMID: 20596675
Journal: World J Gastroenterol. 2010 Jul 14;16(26):3258-66.
Title: CD74 is a survival receptor on colon epithelial cells.
Author: Maharshak, Nitsan|Cohen, Sivan|Lantner, Frida|Hart, Gili|Leng, Lin|Bucala, Richard|Shachar, Idit
PMID: 20614481
Journal: Tumour Biol. 2010 Dec;31(6):623-31.
Title: PI3-kinase/Wnt association mediates COX-2/PGE(2) pathway to inhibit apoptosis in early stages of colon carcinogenesis: chemoprevention by diclofenac.
Author: Kaur, Jasmeet|Sanyal, Sankar Nath
PMID: 20617408
Journal: Carcinogenesis. 2010 Sep;31(9):1604-11.
Title: Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Author: Slattery, Martha L|Herrick, Jennifer S|Lundgreen, Abbie|Fitzpatrick, Francis A|Curtin, Karen|Wolff, Roger K
PMID: 20622004
Journal: Cancer Sci. 2010 Sep;101(9):2011-8.
Title: Significance of integrin alphavbeta5 and erbB3 in enhanced cell migration and liver metastasis of colon carcinomas stimulated by hepatocyte-derived heregulin.
Author: Yoshioka, Toshiaki|Nishikawa, Yuji|Ito, Reiko|Kawamata, Makiko|Doi, Yuko|Yamamoto, Yohei|Yoshida, Masayuki|Omori, Yasufumi|Kotanagi, Hitoshi|Masuko, Takashi|Enomoto, Katsuhiko
PMID: 20626753
Journal: Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1527-35.
Title: Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin.
Author: Chen, Wen-Shu|Lee, Yi-Jang|Yu, Yi-Chu|Hsaio, Ching-Hui|Yen, Jui-Hung|Yu, Sz-Hsien|Tsai, Yu-Jia|Chiu, Shu-Jun
PMID: 20637980
Journal: Oncogene. 2010 Sep 23;29(38):5241-53.
Title: Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas.
Author: Holgren, C|Dougherty, U|Edwin, F|Cerasi, D|Taylor, I|Fichera, A|Joseph, L|Bissonnette, M|Khare, S
PMID: 20661223
Journal: Int J Mol Med. 2010 Sep;26(3):341-9.
Title: Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells.
Author: Auyeung, Kathy Ka-Wai|Mok, Nga-Lai|Wong, Ching-Man|Cho, Chi-Hin|Ko, Joshua Ka-Shun
PMID: 20664949
Journal: Biochem Biophys Res Commun. 2010 Aug 27;399(3):434-9.
Title: Integrin alpha8beta1 confers anoikis susceptibility to human intestinal epithelial crypt cells.
Author: Benoit, Yannick D|Larrivee, Jean-Francois|Groulx, Jean-Francois|Stankova, Jana|Vachon, Pierre H|Beaulieu, Jean-Francois
PMID: 20678483
Journal: Dev Cell. 2010 Aug 17;19(2):259-69.
Title: Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Author: Ashton, Gabrielle H|Morton, Jennifer P|Myant, Kevin|Phesse, Toby J|Ridgway, Rachel A|Marsh, Victoria|Wilkins, Julie A|Athineos, Dimitris|Muncan, Vanesa|Kemp, Richard|Neufeld, Kristi|Clevers, Hans|Brunton, Valerie|Winton, Douglas J|Wang, Xiaoyan|Sears, Ros
PMID: 20708588
Journal: Arch Pharm (Weinheim). 2010 Sep;343(9):489-99.
Title: Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials.
Author: Shehzad, Adeeb|Wahid, Fazli|Lee, Young Sup
PMID: 20726007
Journal: Regul Pept. 2010 Dec 10;165(2-3):224-31.
Title: The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway.
Author: Patel, Oneel|Marshall, Kathryn M|Bramante, Gianni|Baldwin, Graham S|Shulkes, Arthur
PMID: 20727916
Journal: J Pharmacol Exp Ther. 2010 Nov;335(2):351-61.
Title: Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.
Author: Liu, Yanxia|Salvador, Lilibeth A|Byeon, Seongrim|Ying, Yongcheng|Kwan, Jason C|Law, Brian K|Hong, Jiyong|Luesch, Hendrik
PMID: 20739454
Journal: Clin Cancer Res. 2010 Oct 15;16(20):4990-5001.
Title: Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells.
Author: Martinelli, Erika|Troiani, Teresa|Morgillo, Floriana|Rodolico, Gabriella|Vitagliano, Donata|Morelli, Maria Pia|Tuccillo, Concetta|Vecchione, Loredana|Capasso, Anna|Orditura, Michele|De Vita, Ferdinando|Eckhardt, S Gail|Santoro, Massimo|Berrino, Liberato|C
PMID: 20810384
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2010 Aug;30(8):1817-9, 1823.
Title: [Effect of anti-EGFR monoclonal antibody on chemosensitivity of human colon cancer cells and the mechanism].
Author: Cao, Meng-ran|Li, Xiao-yan|Zheng, Da-yong|Yang, Lin|Lv, Cheng-wei|Luo, Rong-cheng
PMID: 20813673
Journal: Diabetologia. 2010 Dec;53(12):2667-75.
Title: Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor.
Author: Yehezkel, E|Weinstein, D|Simon, M|Sarfstein, R|Laron, Z|Werner, H
PMID: 20835859
Journal: Cancer Res. 2010 Oct 1;70(19):7710-22.
Title: Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Author: Boissan, Mathieu|De Wever, Olivier|Lizarraga, Floria|Wendum, Dominique|Poincloux, Renaud|Chignard, Nicolas|Desbois-Mouthon, Christele|Dufour, Sylvie|Nawrocki-Raby, Beatrice|Birembaut, Philippe|Bracke, Marc|Chavrier, Philippe|Gespach, Christian|Lacombe, Ma
PMID: 20841469
Journal: Inflamm Bowel Dis. 2010 Nov;16(11):1871-81.
Title: Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation.
Author: Diegelmann, Julia|Seiderer, Julia|Niess, Jan-Hendrik|Haller, Dirk|Goke, Burkhard|Reinecker, Hans-Christian|Brand, Stephan
PMID: 20848509
Journal: J Agric Food Chem. 2010 Oct 27;58(20):11148-55.
Title: Phenethyl isothiocyanate inhibited tumor migration and invasion via suppressing multiple signal transduction pathways in human colon cancer HT29 cells.
Author: Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Ip, Siu-Wan|Yang, Jai-Sing|Hsu, Yuan-Man|Huang, Hui-Ying|Wu, Shin-Hwar|Chung, Jing-Gung
PMID: 20863062
Journal: Int J Oncol. 2010 Nov;37(5):1345-52.
Title: Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: the role of reactive oxygen species and Akt.
Author: Zhao, Xiao-Chun|Tian, Li|Cao, Jian-Guo|Liu, Fei
PMID: 20878083
Journal: Nutr Cancer. 2010;62(7):919-30.
Title: Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
Author: Goel, Ajay|Aggarwal, Bharat B
PMID: 20924967
Journal: Clin Cancer Res. 2010 Nov 15;16(22):5436-46.
Title: The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models.
Author: Flanigan, Sara A|Pitts, Todd M|Eckhardt, S Gail|Tentler, John J|Tan, Aik Choon|Thorburn, Andrew|Leong, Stephen
PMID: 20943761
Journal: Mediators Inflamm. 2010;2010.
Title: The p110alpha and p110beta isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells.
Author: Ivison, Sabine M|Khan, Mohammed A S|Graham, Nicholas R|Shobab, Leila A|Yao, Yu|Kifayet, Arnawaz|Sly, Laura M|Steiner, Theodore S
PMID: 20953381
Journal: Mol Cancer Ther. 2010 Dec;9(12):3158-63.
Title: Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis.
Author: Dumstorf, Chad A|Konicek, Bruce W|McNulty, Ann M|Parsons, Stephen H|Furic, Luc|Sonenberg, Nahum|Graff, Jeremy R
PMID: 20971826
Journal: Oncol Rep. 2010 Dec;24(6):1471-7.
Title: Anthocyanins are novel AMPKalpha1 stimulators that suppress tumor growth by inhibiting mTOR phosphorylation.
Author: Lee, Yun-Kyoung|Lee, Won Sup|Kim, Gon Sup|Park, Ock Jin
PMID: 21042741
Journal: Mol Cancer Res. 2010 Dec;8(12):1579-90.
Title: FMNL2 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition.
Author: Li, Yufa|Zhu, Xiling|Zeng, Yuanfeng|Wang, Jianmei|Zhang, Xiaojing|Ding, Yan-qing|Liang, Li
PMID: 21071512
Journal: Pharmacology. 2010;86(5-6):313-9.
Title: Pifithrin-alpha, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway.
Author: Kim, Sangmin|Han, Jeonghun|Lee, Se Kyung|Hur, Sung Mo|Koo, Minyoung|Cho, Dong Hui|Bae, Soo Youn|Choi, Min-Young|Shin, Incheol|Yang, Jung-Hyun|Nam, Seok Jin|Lee, Jeong Eon
PMID: 21071999
Journal: Cancer Cell. 2010 Nov 16;18(5):459-71.
Title: B55beta-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.
Author: Tan, Jing|Lee, Puay Leng|Li, Zhimei|Jiang, Xia|Lim, Yaw Chyn|Hooi, Shing Chuan|Yu, Qiang
PMID: 21075311
Journal: Pharmacol Rep. 2010 Sep-Oct;62(5):926-37.
Title: Effect of erythropoietin, 5-fluorouracil and SN-38 on the growth of DLD-1 cells.
Author: Tankiewicz-Kwedlo, Anna|Pawlak, Dariusz|Domaniewski, Tomasz|Buczko, Wlodzimierz
PMID: 21098876
Journal: Nutr Res Pract. 2010 Oct;4(5):351-5.
Title: Significance of p27 as potential biomarker for intracellular oxidative status.
Author: Quintos, Lesley|Lee, In Ae|Kim, Hyo Jung|Lim, Ji-Sun|Park, Jia|Sung, Mi-Kyung|Seo, Young Rok|Kim, Jong-Sang
PMID: 21103079
Journal: Oncology. 2010;79(3-4):278-82.
Title: Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer.
Author: Kim, Jong Gwang|Chae, Yee Soo|Sohn, Sang Kyun|Kang, Byung Woog|Moon, Joon Ho|Lee, Soo Jung|Jeon, Seong Woo|Park, Jun Seok|Park, Jin Young|Choi, Gyu Seog
PMID: 21412012
Journal: Invest New Drugs. 2011 Apr;29(2):207-24.
Title: Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2.
Author: Nagendraprabhu, Ponnuraj|Sudhandiran, Ganapasam
PMID: 19876598
Journal: Apoptosis. 2011 Jan;16(1):35-44.
Title: Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Author: Ray, Ramesh M|Bhattacharya, Sujoy|Johnson, Leonard R
PMID: 20812030
Journal: Pathol Oncol Res. 2011 Jun;17(2):257-61.
Title: Activation of the PI3K/Akt pathway mediates bone morphogenetic protein 2-induced invasion of pancreatic cancer cells Panc-1.
Author: Chen, Xiong|Liao, Jie|Lu, YeBin|Duan, XiaoHui|Sun, WeiJia
PMID: 20848249
Journal: Eur J Clin Invest. 2011 Jan;41(1):84-92.
Title: Relative down-regulation of apoptosis and autophagy genes in colorectal cancer.
Author: Chang, Ying-Tse|Tseng, Hsien-Chun|Huang, Chi-Chou|Chen, Ya-Pei|Chiang, Huei-Ching|Chou, Fen-Pi
PMID: 20880300
Journal: Oncogene. 2011 Feb 10;30(6):737-50.
Title: Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling.
Author: Kitajima, S|Miki, T|Takegami, Y|Kido, Y|Noda, M|Hara, E|Shamma, A|Takahashi, C
PMID: 20890302
Journal: Gastroenterology. 2011 Jan;140(1):297-309.
Title: Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
Author: Lombardo, Ylenia|Scopelliti, Alessandro|Cammareri, Patrizia|Todaro, Matilde|Iovino, Flora|Ricci-Vitiani, Lucia|Gulotta, Gaspare|Dieli, Francesco|de Maria, Ruggero|Stassi, Giorgio
PMID: 20951698
Journal: J Leukoc Biol. 2011 Jan;89(1):85-91.
Title: Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer.
Author: Yang, Shaobo|Wang, Binquan|Guan, Chunying|Wu, Benyan|Cai, Changhao|Wang, Mengwei|Zhang, Binsheng|Liu, Tao|Yang, Pingchang
PMID: 20952660
Journal: Oncogene. 2011 Feb 3;30(5):561-74.
Title: Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab.
Author: Dunn, E F|Iida, M|Myers, R A|Campbell, D A|Hintz, K A|Armstrong, E A|Li, C|Wheeler, D L
PMID: 20956938
Journal: Mol Med. 2011 Jan-Feb;17(1-2):48-58.
Title: Activation of membrane androgen receptors in colon cancer inhibits the prosurvival signals Akt/bad in vitro and in vivo and blocks migration via vinculin/actin signaling.
Author: Gu, Shuchen|Papadopoulou, Natalia|Nasir, Omaima|Foller, Michael|Alevizopoulos, Konstantinos|Lang, Florian|Stournaras, Christos
PMID: 20957335
Journal: Eur J Pharmacol. 2011 Jan 10;650(1):145-50.
Title: Rho-kinase inhibitor upregulates migration by altering focal adhesion formation via the Akt pathway in colon cancer cells.
Author: Adachi, Seiji|Yasuda, Ichiro|Nakashima, Masanori|Yamauchi, Takahiro|Yoshioka, Takashi|Okano, Yukio|Moriwaki, Hisataka|Kozawa, Osamu
PMID: 20959118
Journal: Mutat Res. 2011 Jan 10;706(1-2):13-20.
Title: Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K
PMID: 21035469
Journal: Cancer Lett. 2011 Jan 28;300(2):197-204.
Title: Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells.
Author: Akao, Yukihiro|Noguchi, Shunsuke|Iio, Akio|Kojima, Keitaro|Takagi, Takeshi|Naoe, Tomoki
PMID: 21067862
Journal: Cancer Res. 2011 Jan 1;71(1):234-44.
Title: Phosphatase PRL-3 is a direct regulatory target of TGFbeta in colon cancer metastasis.
Author: Jiang, Yanjun|Liu, Xiao-Qiong|Rajput, Ashwani|Geng, Liying|Ongchin, Melanie|Zeng, Qi|Taylor, Gregory S|Wang, Jing
PMID: 21084277
Journal: Phytother Res. 2011 Jun;25(6):833-7.
Title: Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.
Author: Lee, Myung Sun|Cha, Eun Young|Sul, Ji Young|Song, In Sang|Kim, Ji Yeon
PMID: 21089180
Journal: Clin Cancer Res. 2011 Feb 1;17(3):472-82.
Title: HGF rescues colorectal cancer cells from EGFR inhibition via MET activation.
Author: Liska, David|Chen, Chin-Tung|Bachleitner-Hofmann, Thomas|Christensen, James G|Weiser, Martin R
PMID: 21098338
Journal: Cancer Biol Ther. 2011 Jan 1;11(1):111-21. Epub 2011 Jan 1.
Title: Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease.
Author: Feng, Yin-Hsun|Wu, Chao-Liang|Tsao, Chao-Jung|Chang, Jan-Gowth|Lu, Pei-Jung|Yeh, Kun-Tu|Uen, Yih-Huei|Lee, Jeng-Chang|Shiau, Ai-Li
PMID: 21099344
Journal: Br J Cancer. 2011 Jan 4;104(1):146-54.
Title: Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells.
Author: Watanabe, T|Semba, S|Yokozaki, H
PMID: 21102582
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72.
Title: Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.
Author: Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Roy, Hemant|Wali, Ramesh|Joshi, Suhasini|Savkovic, Suzana D
PMID: 21109589
Journal: Eur J Clin Invest. 2011 Mar;41(3):277-84.
Title: Anti-interleukin-6 receptor antibody inhibits the progression in human colon carcinoma cells.
Author: Hsu, Chih-Ping|Chen, Yung-Liang|Huang, Chiu-Chen|Chou, Chih-Chung|Liu, Chia-Ling|Hung, Chih-Hung|Kao, Ting-Yu|Chung, Yuan-Chiang
PMID: 21114487
Journal: Curr Cancer Drug Targets. 2011 Feb;11(2):190-8.
Title: PI-3-Kinase inhibitors in colorectal cancer.
Author: Ihle, N T|Powis, G|Kopetz, S
PMID: 21158718
Journal: Nutr Cancer. 2011;63(1):139-50.
Title: Estrogen receptor-beta mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones.
Author: Bielecki, Agnieszka|Roberts, Jennifer|Mehta, Rekha|Raju, Jayadev
PMID: 21161820
Journal: Lancet Oncol. 2011 Jun;12(6):594-603.
Title: KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Author: De Roock, Wendy|De Vriendt, Veerle|Normanno, Nicola|Ciardiello, Fortunato|Tejpar, Sabine
PMID: 21163703
Journal: Oncol Rep. 2011 Feb;25(2):567-72.
Title: Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cells.
Author: Shin, Dong Yeok|Lu, Jing Nan|Kim, Gi-Young|Jung, Jin Myung|Kang, Ho Sung|Lee, Won Sup|Choi, Yung Hyun
PMID: 21165577
Journal: Mol Cancer Res. 2011 Feb;9(2):173-82.
Title: Functional genomics reveals diverse cellular processes that modulate tumor cell response to oxaliplatin.
Author: Harradine, Kelly A|Kassner, Michelle|Chow, Donald|Aziz, Meraj|Von Hoff, Daniel D|Baker, Joffre B|Yin, Hongwei|Pelham, Robert J
PMID: 21169384
Journal: Oncol Rep. 2011 Mar;25(3):789-94.
Title: Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author: Aoyagi, Haruhiko|Iida, Satoru|Uetake, Hiroyuki|Ishikawa, Toshiaki|Takagi, Yoko|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Yasuno, Masamichi|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 21174064
Journal: J Biol Chem. 2011 Feb 25;286(8):6510-20.
Title: mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
Author: Liu, Jianyu|Stevens, Payton D|Gao, Tianyan
PMID: 21177869
Journal: Cancer Res. 2011 Jan 1;71(1):206-15.
Title: Activation and involvement of Ral GTPases in colorectal cancer.
Author: Martin, Timothy D|Samuel, Jonathan C|Routh, Elizabeth D|Der, Channing J|Yeh, Jen Jen
PMID: 21199803
Journal: Am J Physiol Cell Physiol. 2011 Mar;300(3):C657-70.
Title: Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis.
Author: Wang, Shouye|Basson, Marc D
PMID: 21209368
Journal: Mol Cancer Ther. 2011 Mar;10(3):558-65.
Title: PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors.
Author: Janku, Filip|Tsimberidou, Apostolia M|Garrido-Laguna, Ignacio|Wang, Xuemei|Luthra, Rajyalakshmi|Hong, David S|Naing, Aung|Falchook, Gerald S|Moroney, John W|Piha-Paul, Sarina A|Wheler, Jennifer J|Moulder, Stacy L|Fu, Siqing|Kurzrock, Razelle
PMID: 21216929
Journal: Cancer Res. 2011 Mar 1;71(5):1849-57.
Title: Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
Author: Konicek, Bruce W|Stephens, Jennifer R|McNulty, Ann M|Robichaud, Nathaniel|Peery, Robert B|Dumstorf, Chad A|Dowless, Michele S|Iversen, Philip W|Parsons, Stephen|Ellis, Karen E|McCann, Denis J|Pelletier, Jerry|Furic, Luc|Yingling, Jonathan M|Stancato, Loui
PMID: 21233335
Journal: Cancer Res. 2011 Mar 1;71(5):1647-57.
Title: The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Author: Pez, Floriane|Dayan, Frederic|Durivault, Jerome|Kaniewski, Bastien|Aimond, Geraldine|Le Provost, Gabrielle S|Deux, Blandine|Clezardin, Philippe|Sommer, Pascal|Pouyssegur, Jacques|Reynaud, Caroline
PMID: 21239473
Journal: Int J Biol Macromol. 2011 Apr 1;48(3):511-7.
Title: Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.
Author: Li, You-Gui|Ji, Dong-Feng|Zhong, Shi|Zhu, Jian-Xun|Chen, Shi|Hu, Gui-Yan
PMID: 21262260
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: Cancer Sci. 2011 May;102(5):999-1006.
Title: Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells.
Author: Habeeb, Baker S|Kitayama, Joji|Nagawa, Hirokazu
PMID: 21299716
Journal: J Surg Res. 2011 May 15;167(2):e193-8.
Title: Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
Author: Benoit, Michael|Dormond-Meuwly, Anne|Demartines, Nicolas|Dormond, Olivier
PMID: 21324487
Journal: Mol Biol Cell. 2011 Apr 15;22(8):1121-34.
Title: Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/beta-catenin signaling.
Author: Kolegraff, Keli|Nava, Porfirio|Helms, My N|Parkos, Charles A|Nusrat, Asma
PMID: 21325624
Journal: PLoS One. 2011 Feb 15;6(2):e16916.
Title: ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.
Author: Gan, Lihong|Chen, Shujie|Zhong, Jing|Wang, Xian|Lam, Emily K Y|Liu, Xin|Zhang, Jianbin|Zhou, Tianhua|Yu, Jun|Si, Jianmin|Wang, Liangjing|Jin, Hongchuan
PMID: 21347233
Journal: World J Gastroenterol. 2011 Feb 7;17(5):625-32.
Title: Influence of CXCR4/SDF-1 axis on E-cadherin/beta-catenin complex expression in HT29 colon cancer cells.
Author: Wang, Lin|Li, Cui-Ling|Wang, Lei|Yu, Wen-Bin|Yin, Hai-Peng|Zhang, Guang-Yong|Zhang, Li-Feng|Li, Sheng|Hu, San-Yuan
PMID: 21350711
Journal: Cancer Res. 2011 Mar 1;71(5):1989-98.
Title: LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis.
Author: Hsu, Rich Y C|Chan, Carlos H F|Spicer, Jonathan D|Rousseau, Mathieu C|Giannias, Betty|Rousseau, Simon|Ferri, Lorenzo E
PMID: 21363926
Journal: J Mol Signal. 2011 Mar 3;6:2.
Title: Activation of K-RAS by co-mutation of codons 19 and 20 is transforming.
Author: Naguib, Adam|Wilson, Catherine H|Adams, David J|Arends, Mark J
PMID: 21371307
Journal: PLoS One. 2011 Feb 17;6(2):e16871.
Title: Functional characterization of human cancer-derived TRKB mutations.
Author: Geiger, Thomas R|Song, Ji-Ying|Rosado, Aranzazu|Peeper, Daniel S
PMID: 21379385
Journal: Cancer Lett. 2011 Jun 1;305(1):1-7.
Title: Carnosol: a promising anti-cancer and anti-inflammatory agent.
Author: Johnson, Jeremy J
PMID: 21382660
Journal: Mol Med. 2011;17(7-8):607-18.
Title: A functional variant of IC53 correlates with the late onset of colorectal cancer.
Author: Chen, Jingzhou|Shi, Yi|Li, Ziyu|Yu, Hui|Han, Yu|Wang, Xiaojian|Sun, Kai|Yang, Tao|Lou, Kejia|Song, Yan|Zhang, Yinhui|Zhen, Yisong|Zhang, Guiguo|Hu, Ying|Ji, Jiafu|Hui, Rutai
PMID: 21394385
Journal: J Dig Dis. 2011 Apr;12(2):110-6.
Title: RNA interference (RNAi) of Ufd1 protein can sensitize a hydroxycamptothecin-resistant colon cancer cell line SW1116/HCPT to hydroxycamptothecin.
Author: Chen, Xiang|Ran, Zhi Hua|Tong, Jin Lu|Nie, Fang|Zhu, Ming Ming|Xu, Xi Tao|Xiao, Shu Dong
PMID: 21401896
Journal: Angiogenesis. 2011 May;14(2):209-21.
Title: Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo.
Author: Tammali, Ravinder|Reddy, Aramati B M|Srivastava, Satish K|Ramana, Kota V
PMID: 21409599
Journal: Cancer. 2011 Apr 1;117(7):1399-408.
Title: Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.
Author: Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Hayashi, Marika|Meyerhardt, Jeffrey A|Chan, Andrew T|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21425139
Journal: Cancer Lett. 2011 Jul 28;306(2):151-60.
Title: Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer.
Author: Xu, Rui|Nakano, Kenji|Iwasaki, Hironori|Kumagai, Michiaki|Wakabayashi, Rie|Yamasaki, Akio|Suzuki, Hiroyuki|Mibu, Ryuichi|Onishi, Hideya|Katano, Mitsuo
PMID: 21429662
Journal: Cancer Res. 2011 May 1;71(9):3246-56.
Title: mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Author: Gulhati, Pat|Bowen, Kanika A|Liu, Jianyu|Stevens, Payton D|Rychahou, Piotr G|Chen, Min|Lee, Eun Y|Weiss, Heidi L|O'Connor, Kathleen L|Gao, Tianyan|Evers, B Mark
PMID: 21430067
Journal: PLoS Curr. 2011 Mar 16;3:RRN1223.
Title: Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies.
Author: Weichselbaumer, Marlene|Willmann, Michael|Reifinger, Martin|Singer, Josef|Bajna, Erika|Sobanov, Yuriy|Mechtcherikova, Diana|Selzer, Edgar|Thalhammer, Johann G|Kammerer, Robert|Jensen-Jarolim, Erika
PMID: 21436956
Journal: Inflamm Res. 2011 Aug;60(8):727-34.
Title: PI3K/Akt signaling pathway is involved in the pathogenesis of ulcerative colitis.
Author: Huang, Xiao Li|Xu, Jin|Zhang, Xiao Hui|Qiu, Bo Yun|Peng, Lan|Zhang, Meng|Gan, Hua Tian
PMID: 21442372
Journal: J Biol Chem. 2011 May 6;286(18):16082-90.
Title: Restoration of transforming growth factor-beta receptor II expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo.
Author: Liu, Xiao-Qiong|Rajput, Ashwani|Geng, Liying|Ongchin, Melanie|Chaudhuri, Anathbandhu|Wang, Jing
PMID: 21454688
Journal: Eur J Pharmacol. 2011 Jun 25;660(2-3):249-58.
Title: Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway.
Author: Umesalma, Syed|Sudhandiran, Ganapasam
PMID: 21463623
Journal: Cancer Res. 2011 May 15;71(10):3635-48.
Title: The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.
Author: LaBonte, Melissa J|Wilson, Peter M|Fazzone, Will|Russell, Jared|Louie, Stan G|El-Khoueiry, Anthony|Lenz, Heinz-Josef|Ladner, Robert D
PMID: 21464044
Journal: PLoS One. 2011 Mar 25;6(3):e18087.
Title: HDAC inhibition decreases the expression of EGFR in colorectal cancer cells.
Author: Chou, Chia-Wei|Wu, Ming-Shiang|Huang, Wei-Chien|Chen, Ching-Chow
PMID: 21464950
Journal: Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106.
Title: Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Author: Colin, Didier|Limagne, Emeric|Jeanningros, Sylvie|Jacquel, Arnaud|Lizard, Gerard|Athias, Anne|Gambert, Philippe|Hichami, Aziz|Latruffe, Norbert|Solary, Eric|Delmas, Dominique
PMID: 21467134
Journal: Clin Cancer Res. 2011 Jun 1;17(11):3569-78.
Title: HOXB7 as a prognostic factor and mediator of colorectal cancer progression.
Author: Liao, Wen-Ting|Jiang, Dan|Yuan, Jian|Cui, Yan-Mei|Shi, Xi-Wen|Chen, Cui-Min|Bian, Xiu-Wu|Deng, Yong-Jian|Ding, Yan-Qing
PMID: 21474578
Journal: J Gastrointest Surg. 2011 Jun;15(6):942-57.
Title: Phosphorylated insulin-like growth factor 1 receptor is implicated in resistance to the cytostatic effect of gefitinib in colorectal cancer cells.
Author: Yang, Li|Li, Jianjun|Ran, Li|Pan, Feng|Zhao, Xiaoxin|Ding, Zhenyu|Chen, Yuying|Peng, Qiuping|Liang, Houjie
PMID: 21479670
Journal: J Agric Food Chem. 2011 May 25;59(10):5357-63.
Title: Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin.
Author: Chang, Hsiang-Yu|Kao, Ming-Ching|Way, Tzong-Der|Ho, Chi-Tang|Fu, Earl
PMID: 21504235
Journal: Curr Drug Discov Technol. 2011 Jun;8(2):119-25.
Title: Insulin decreases therapeutic efficacy in colon cancer cell line HT29 via the activation of the PI3K/Akt pathway.
Author: Chen, Jiezhong|Katsifis, Andrew|Hu, Changhua|Huang, Xu-Feng
PMID: 21513489
Journal: Int J Oncol. 2011 Jul;39(1):23-31.
Title: Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo.
Author: Yamaguchi, Takayuki|Kakefuda, Reina|Tajima, Nobuyuki|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 21523318
Journal: Clin Cancer Res. 2011 Jul 1;17(13):4474-83.
Title: The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
Author: Sharma, Arun K|Kline, Christina L|Berg, Arthur|Amin, Shantu|Irby, Rosalyn B
PMID: 21555373
Journal: Cancer Lett. 2011 Sep 1;308(1):62-70.
Title: RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-kappaB in colon carcinoma HCT116 cells.
Author: Zhang, Hao|Zhang, Shenghua|He, Hongwei|Zhao, Wuli|Ren, Kaihuan|Chen, Jianhua|Shao, Rong-guang
PMID: 21570766
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Apr;33(4):256-9.
Title: [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts].
Author: Liao, Yu-Sheng|Wu, Jie|Wang, Ping|Zhang, Heng
PMID: 21575494
Journal: J Biol Chem. 2011 Jul 8;286(27):24089-100.
Title: Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
Author: Tammali, Ravinder|Saxena, Ashish|Srivastava, Satish K|Ramana, Kota V
PMID: 21576240
Journal: Mol Cell Biochem. 2011 Nov;357(1-2):31-8.
Title: Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells.
Author: Li, Jian|Zhang, Yangde|Zhao, Jingfeng|Kong, Fangren|Chen, Yuxiang
PMID: 21594648
Journal: Chem Biol Interact. 2011 Aug 15;193(1):43-9.
Title: Antitumor effects of a novel benzonaphthofurandione derivative (8e) on the human colon cancer cells in vitro and in vivo through cell cycle arrest accompanied with the modulation of EGFR and mTOR signaling.
Author: Chung, Hwa-Jin|Rhee, Hee-Kyung|Lee, Sang Kook|Park Choo, Hea-Young
PMID: 21600193
Journal: Int J Mol Med. 2011 Oct;28(4):637-43.
Title: Aspirin reduces the apoptotic effect of etoposide via Akt activation and up-regulation of p21(cip).
Author: Feng, Xiaocheng|Lu, Bin|Xu, Yingying|Li, Qin|Zhou, Wenbai|Yang, Zhihong|Yang, Zeng|Zhao, Weiwei|Shen, Zonghou|Hu, Renming
PMID: 21617849
Journal: Cell Signal. 2011 Sep;23(9):1505-13.
Title: An IkappaBalpha phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-kappaB-independent mechanism.
Author: Min, Kyoung-jin|Lee, Jung Tae|Joe, Eun-hye|Kwon, Taeg Kyu
PMID: 21620964
Journal: Mol Cell Proteomics. 2011 Oct;10(10):M110.005397.
Title: Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells.
Author: Lei, Yunlong|Huang, Kai|Gao, Cong|Lau, Quek Choon|Pan, Hua|Xie, Ke|Li, Jingyi|Liu, Rui|Zhang, Tao|Xie, Na|Nai, Huey Shan|Wu, Hong|Dong, Qiang|Zhao, Xia|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 21622897
Journal: Mol Cell Biochem. 2011 Nov;357(1-2):255-62.
Title: Dual role of insulin-like growth factor-1 in acetyl-CoA carboxylase-alpha activity in human colon cancer cells HCT-8: downregulating its expression and phosphorylation.
Author: Luo, Di-Xian|Peng, Xu-hong|Xiong, Yan|Liao, Duan-Fang|Cao, Deliang|Li, Longjiang
PMID: 21638027
Journal: BMC Cancer. 2011 Jun 3;11:219.
Title: Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.
Author: Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Savkovic, Suzana D
PMID: 21639915
Journal: J Biol Chem. 2011 Jul 22;286(29):26178-87.
Title: Ultraviolet irradiation can induce evasion of colon cancer cells from stimulation of epidermal growth factor.
Author: Adachi, Seiji|Yasuda, Ichiro|Nakashima, Masanori|Yamauchi, Takahiro|Kawaguchi, Junji|Shimizu, Masahito|Itani, Masahiko|Nakamura, Momoko|Nishii, Yumi|Yoshioka, Takashi|Hirose, Yoshinobu|Okano, Yukio|Moriwaki, Hisataka|Kozawa, Osamu
PMID: 21646361
Journal: Mol Nutr Food Res. 2011 Oct;55(10):1523-32.
Title: The inhibitory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells.
Author: Qiu, Peiju|Guan, Huashi|Dong, Ping|Guo, Shanshan|Zheng, Jinkai|Li, Shiming|Chen, Yun|Ho, Chi-Tang|Pan, Min-Hsiung|McClements, David Julian|Xiao, Hang
PMID: 21648071
Journal: J Cell Physiol. 2011 Sep;226(9):2316-28.
Title: Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
Author: Irwin, Mary E|Mueller, Kelly L|Bohin, Natacha|Ge, Yubin|Boerner, Julie L
PMID: 21660955
Journal: Mol Cancer Ther. 2011 Aug;10(8):1394-406.
Title: Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin.
Author: Bhagwat, Shripad V|Gokhale, Prafulla C|Crew, Andrew P|Cooke, Andy|Yao, Yan|Mantis, Christine|Kahler, Jennifer|Workman, Jennifer|Bittner, Mark|Dudkin, Lorina|Epstein, David M|Gibson, Neil W|Wild, Robert|Arnold, Lee D|Houghton, Peter J|Pachter, Jonathan A
PMID: 21673091
Journal: Tumour Biol. 2011 Oct;32(5):965-76.
Title: Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells.
Author: Dabrowska, Magdalena|Skoneczny, Marek|Rode, Wojciech
PMID: 21678067
Journal: J Exp Ther Oncol. 2011;9(2):119-27.
Title: Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.
Author: Gao, Xiaohua|Deeb, Dorrah|Liu, Patricia|Liu, Yongbo|Arbab-Ali, Syed|Dulchavsky, Scott A|Gautam, Subhash C
PMID: 21699019
Journal: Cell Cycle. 2011 Jul 15;10(14):2331-8. Epub 2011 Jul 15.
Title: Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab.
Author: Hart, Lori S|Dolloff, Nathan G|Dicker, David T|Koumenis, Constantinos|Christensen, James G|Grimberg, Adda|El-Deiry, Wafik S
PMID: 21720213
Journal: BMC Cancer. 2011 Jul 1;11:285.
Title: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3.
Author: Porquet, Nicolas|Poirier, Andree|Houle, Francois|Pin, Anne-Laure|Gout, Stephanie|Tremblay, Pierre-Luc|Paquet, Eric R|Klinck, Roscoe|Auger, Francois A|Huot, Jacques
PMID: 21722370
Journal: Mol Cancer. 2011 Jul 3;10:79.
Title: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Author: Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kawaguchi, Junji|Hanamatsu, Toshimasa|Yoshioka, Takashi|Okano, Yukio|Hirose, Yoshinobu|Kozawa, Osamu|Moriwaki, Hisataka
PMID: 21722395
Journal: Radiother Oncol. 2011 Oct;101(1):140-6.
Title: Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation.
Author: Toulany, Mahmoud|Schickfluss, Tim-Andre|Fattah, Kazi R|Lee, Kyung-Jong|Chen, Benjamin P C|Fehrenbacher, Birgit|Schaller, Martin|Chen, David J|Rodemann, H Peter
PMID: 21723633
Journal: Anticancer Res. 2011 Jun;31(6):2217-24.
Title: NK4 gene expression enhances 5-fluorouracil-induced apoptosis of murine colon cancer cells.
Author: Taiyoh, Hiroaki|Kubota, Takeshi|Fujiwara, Hitoshi|Matsumura, Atsushi|Murayama, Yasutoshi|Okamoto, Kazuma|Ichikawa, Daisuke|Ochiai, Toshiya|Nakamura, Takahiro|Matsumoto, Kunio|Nakamura, Toshikazu|Otsuji, Eigo
PMID: 21737644
Journal: Mod Pathol. 2011 Oct;24(10):1404-12.
Title: VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
Author: Vlajnic, Tatjana|Andreozzi, Maria Carla|Schneider, Sandra|Tornillo, Luigi|Karamitopoulou, Eva|Lugli, Alessandro|Ruiz, Christian|Zlobec, Inti|Terracciano, Luigi
PMID: 21743435
Journal: Gan To Kagaku Ryoho. 2011 Jul;38(7):1079-83.
Title: [Predictive biomarkers of anti-EGFR monoclonal anti-body in colorectal cancer].
Author: Soeda, Hiroshi|Shimodaira, Hideki|Ishioka, Chikashi
PMID: 21772090
Journal: Biochem Biophys Res Commun. 2011 Aug 12;411(4):751-6.
Title: Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
Author: Yu, Zhiwei|Cui, Binbin|Jin, Yinghu|Chen, Haipeng|Wang, Xishan
PMID: 21782788
Journal: Biol Cell. 2011 Nov;103(11):519-29.
Title: alphav integrin processing interferes with the cross-talk between alphavbeta5/beta6 and alpha2beta1 integrins.
Author: Defilles, Celine|Montero, Marie-Pierre|Lissitzky, Jean-Claude|Rome, Sophie|Siret, Carole|Luis, Jose|Andre, Frederic|Rigot, Veronique
PMID: 21787362
Journal: Ann N Y Acad Sci. 2011 Jul;1229:61-8.
Title: Obesity-induced metabolic stresses in breast and colon cancer.
Author: Sung, Mi-Kyung|Yeon, Jee-Young|Park, Shin-Young|Park, Jung Han Yoon|Choi, Myung-Sook
PMID: 21793840
Journal: Biol Pharm Bull. 2011;34(8):1231-9.
Title: Deltonin isolated from Dioscorea zingiberensis inhibits cancer cell growth through inducing mitochondrial apoptosis and suppressing Akt and mitogen activated protein kinase signals.
Author: Shu, Dan|Qing, Yong|Tong, Qingyi|He, Yang|Xing, Zhihua|Zhao, Yinglan|Li, Yi|Wei, Yuquan|Huang, Wen|Wu, Xiaohua
PMID: 21804211
Journal: Transl Oncol. 2011 Aug;4(4):241-8. Epub 2011 Aug 1.
Title: Glucose metabolism measured by [(1)(8)F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells.
Author: Nguyen, Quang-De|Perumal, Meg|Waldman, Todd A|Aboagye, Eric O
PMID: 21804920
Journal: Gastroenterology. 2011 Nov;141(5):1749-61.e1.
Title: Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors.
Author: Bakirtzi, Kyriaki|Hatziapostolou, Maria|Karagiannides, Iordanes|Polytarchou, Christos|Jaeger, Savina|Iliopoulos, Dimitrios|Pothoulakis, Charalabos
PMID: 21806946
Journal: PLoS One. 2011;6(7):e22769.
Title: PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.
Author: Janku, Filip|Lee, J Jack|Tsimberidou, Apostolia M|Hong, David S|Naing, Aung|Falchook, Gerald S|Fu, Siqing|Luthra, Rajyalakshmi|Garrido-Laguna, Ignacio|Kurzrock, Razelle
PMID: 21829508
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G856-64.
Title: Intestinal epithelial-specific PTEN inactivation results in tumor formation.
Author: Byun, Do-Sun|Ahmed, Naseem|Nasser, Shannon|Shin, Joongho|Al-Obaidi, Sheren|Goel, Sanjay|Corner, Georgia A|Wilson, Andrew J|Flanagan, Dustin J|Williams, David S|Augenlicht, Leonard H|Vincan, Elizabeth|Mariadason, John M
PMID: 21836055
Journal: PLoS One. 2011;6(8):e23381.
Title: An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression.
Author: Leushacke, Marc|Sporle, Ralf|Bernemann, Christof|Brouwer-Lehmitz, Antje|Fritzmann, Johannes|Theis, Mirko|Buchholz, Frank|Herrmann, Bernhard G|Morkel, Markus
PMID: 21853123
Journal: J Biomed Sci. 2011 Aug 22;18:61.
Title: JNK suppression is essential for 17beta-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells.
Author: Hsu, Hsi-Hsien|Hu, Wei-Syun|Lin, Yueh-Min|Kuo, Wei-Wen|Chen, Li-Mien|Chen, Wei-Kung|Hwang, Jin-Ming|Tsai, Fuu-Jen|Liu, Chung-Jung|Huang, Chih-Yang
PMID: 21859479
Journal: Chin Med. 2011 Aug 23;6:31.
Title: Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.
Author: Mimeault, Murielle|Batra, Surinder K
PMID: 21859497
Journal: Cell Physiol Biochem. 2011;28(2):219-28.
Title: Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cells.
Author: Santandreu, Francisca M|Valle, Adamo|Oliver, Jordi|Roca, Pilar
PMID: 21865729
Journal: Cancer Res. 2011 Oct 1;71(19):6270-81.
Title: Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.
Author: Chen, Shuzhen|Cao, Wei|Yue, Ping|Hao, Chunhai|Khuri, Fadlo R|Sun, Shi-Yong
PMID: 21868755
Journal: Chem Biol Interact. 2011 Oct 15;194(1):48-57.
Title: Cell cycle arrest and apoptosis induced by methyl 3,5-dicaffeoyl quinate in human colon cancer cells: Involvement of the PI3K/Akt and MAP kinase pathways.
Author: Hu, Weicheng|Shen, Ting|Wang, Myeong-Hyeon
PMID: 21872580
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;36(7):585-91.
Title: [Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages].
Author: Li, Xiayu|Shen, Shourong|Wu, Minghua|Li, Xiaoling|Xiong, Wei|Lu, Jianhong|Zhou, Ming|Ma, Jian|Xiang, Juanjuan|Zeng, Zhaoyang|Xiang, Bo|Zhou, Yanhong|Xiao, Lan|Zhou, Houde|Fan, Songqing|Li, Guiyuan
PMID: 21873780
Journal: Gastroenterology. 2011 Dec;141(6):2140-53.
Title: Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells.
Author: Singh, Amar B|Sharma, Ashok|Smith, J Joshua|Krishnan, Moorthy|Chen, Xi|Eschrich, Steven|Washington, Mary K|Yeatman, Timothy J|Beauchamp, R Daniel|Dhawan, Punita
PMID: 21878201
Journal: Cancer Prev Res (Phila). 2011 Nov;4(11):1842-51.
Title: (3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo.
Author: Kim, Dong Joon|Reddy, Kanamata|Kim, Myoung Ok|Li, Yan|Nadas, Janos|Cho, Yong-Yeon|Kim, Jong-Eun|Shim, Jung-Hyun|Song, Nu Ry|Carper, Andria|Lubet, Ronald A|Bode, Ann M|Dong, Zigang
PMID: 21885813
Journal: Mol Cells. 2011 Nov;32(5):415-9.
Title: GAIP-interacting protein, C-terminus is involved in the induction of zinc-finger protein 143 in response to insulin-like growth factor-1 in colon cancer cells.
Author: Paek, A Rome|You, Hye Jin
PMID: 21909943
Journal: Apoptosis. 2011 Dec;16(12):1285-94.
Title: The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.
Author: Kline, Christina Leah B|Irby, Rosalyn B
PMID: 21910008
Journal: Radiat Oncol. 2011 Sep 12;6:114.
Title: Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy.
Author: Davies, Janine M|Trembath, Dimitri|Deal, Allison M|Funkhouser, William K|Calvo, Benjamin F|Finnegan, Timothy|Weck, Karen E|Tepper, Joel E|O'Neil, Bert H
PMID: 21910869
Journal: Bioorg Med Chem. 2011 Oct 15;19(20):6006-14.
Title: Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway.
Author: Krishnegowda, Gowdahalli|Prakasha Gowda, A S|Tagaram, Hephzibah Rani S|Carroll, Kevin F Staveley-O'|Irby, Rosalyn B|Sharma, Arun K|Amin, Shantu
PMID: 21920762
Journal: J Agric Food Chem. 2011 Oct 26;59(20):11304-18.
Title: Cancer chemopreventive effects of lycopene: suppression of MMP-7 expression and cell invasion in human colon cancer cells.
Author: Lin, Meng-Chiu|Wang, Fu-Yu|Kuo, Yueh-Hsiung|Tang, Feng-Yao
PMID: 21923160
Journal: J Exp Clin Cancer Res. 2011 Sep 16;30:83.
Title: Effects of metastasis-associated in colon cancer 1 inhibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cells.
Author: Zhang, Ruitao|Shi, Huirong|Chen, Zhimin|Wu, Qinghua|Ren, Fang|Huang, Haoliang
PMID: 21923915
Journal: Hepatogastroenterology. 2011 Jul-Aug;58(109):1182-8.
Title: The significance of a group of molecular markers and clinicopathological factors in identifying colorectal liver metastasis.
Author: Wu, Jian-Hui|Tian, Xiu-Yun|Hao, Chun-Yi
PMID: 21937374
Journal: Toxicol In Vitro. 2011 Dec;25(8):1771-81.
Title: Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells.
Author: Ramos, Sonia|Rodriguez-Ramiro, Ildefonso|Martin, Maria Angeles|Goya, Luis|Bravo, Laura
PMID: 21945981
Journal: BMC Cancer. 2011 Oct 2;11:421.
Title: Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.
Author: Muller, Kristin M|Tveteraas, Ingun H|Aasrum, Monica|Odegard, John|Dawood, Mona|Dajani, Olav|Christoffersen, Thoralf|Sandnes, Dagny L
PMID: 21961726
Journal: Am J Pathol. 2011 Dec;179(6):3032-44.
Title: Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.
Author: Uddin, Shahab|Hussain, Azhar R|Ahmed, Maqbool|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Bavi, Prashant|Al-Kuraya, Khawla S
PMID: 21978492
Journal: Clin Cancer Res. 2011 Dec 1;17(23):7337-46.
Title: Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Author: Gotink, Kristy J|Broxterman, Henk J|Labots, Mariette|de Haas, Richard R|Dekker, Henk|Honeywell, Richard J|Rudek, Michelle A|Beerepoot, Laurens V|Musters, Rene J|Jansen, Gerrit|Griffioen, Arjan W|Assaraf, Yehuda G|Pili, Roberto|Peters, Godefridus J|Verheul
PMID: 21980135
Journal: J Clin Invest. 2011 Nov;121(11):4311-21.
Title: Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.
Author: Ebi, Hiromichi|Corcoran, Ryan B|Singh, Anurag|Chen, Zhao|Song, Youngchul|Lifshits, Eugene|Ryan, David P|Meyerhardt, Jeffrey A|Benes, Cyril|Settleman, Jeffrey|Wong, Kwok-Kin|Cantley, Lewis C|Engelman, Jeffrey A
PMID: 21985784
Journal: Nutr Cancer. 2011 Nov;63(8):1226-34.
Title: Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Caan, Bette J|Potter, John D|Wolff, Roger K
PMID: 21999454
Journal: Br J Cancer. 2011 Nov 22;105(11):1759-67.
Title: Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells.
Author: Bose, D|Zimmerman, L J|Pierobon, M|Petricoin, E|Tozzi, F|Parikh, A|Fan, F|Dallas, N|Xia, L|Gaur, P|Samuel, S|Liebler, D C|Ellis, L M
PMID: 22045189
Journal: PLoS One. 2011;6(11):e27308.
Title: A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells.
Author: Bordonaro, Michael|Tewari, Shruti|Cicco, Catherine E|Atamna, Wafa|Lazarova, Darina L
PMID: 22073312
Journal: Mol Cancer. 2011 Nov 23;10:144.
Title: Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma.
Author: Schulze, Daniel|Plohmann, Philipp|Hobel, Sabrina|Aigner, Achim
PMID: 22111880
Journal: Sci Signal. 2011 Nov 22;4(200):pt9.
Title: Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Author: Ruiz i Altaba, Ariel
PMID: 22114144
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Nov;31(11):1914-7.
Title: [Construction of the expression vector for short-hairpin RNA-mediated Akt gene silencing in Lovo cells].
Author: Huang, Xian-zhang|Zhao, Xue-qin|Li, Man|He, Min|Zhunag, Jun-hua
PMID: 22126779
Journal: PLoS One. 2011;6(12):e28841.
Title: Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors.
Author: Morgillo, Floriana|Martinelli, Erika|Troiani, Teresa|Orditura, Michele|De Vita, Ferdinando|Ciardiello, Fortunato
PMID: 22174910
Journal: Mol Cell. 2011 Dec 23;44(6):893-906.
Title: Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
Author: Matallanas, David|Romano, David|Al-Mulla, Fahd|O'Neill, Eric|Al-Ali, Waleed|Crespo, Piero|Doyle, Brendan|Nixon, Colin|Sansom, Owen|Drosten, Matthias|Barbacid, Mariano|Kolch, Walter
PMID: 22195963
Journal: ISRN Endocrinol. 2011;2011:575397.
Title: Cellular signal transduction pathways by leptin in colorectal cancer tissue: preliminary results.
Author: Nowakowska-Zajdel, Ewa|Mazurek, Urszula|Stachowicz, Malgorzata|Niedworok, Elzbieta|Fatyga, Edyta|Muc-Wierzgon, Malgorzata
PMID: 22363883
Journal: J Gastrointest Oncol. 2011 Mar;2(1):27-33.
Title: Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29.
Author: Chen, Jiezhong|Huang, Xu-Feng|Qiao, Liang|Katsifis, Andrew
PMID: 22811824
Journal: Cancers (Basel). 2011 Mar 2;3(1):971-81.
Title: Muscarinic receptor signaling in colon cancer.
Author: Von Rosenvinge, Erik C|Raufman, Jean-Pierre
PMID: 24212649
Journal: Biomol Concepts. 2011 Apr 1;2(1-2):1-11.
Title: Functional specificity of Akt isoforms in cancer progression.
Author: Fortier, Anne-Marie|Asselin, Eric|Cadrin, Monique
PMID: 25962016
Journal: Med Oncol. 2012 Jun;29(2):1005-9.
Title: A decline in weight and attrition of muscle in colorectal cancer patients receiving chemotherapy with bevacizumab.
Author: Poterucha, Timothy|Burnette, Brian|Jatoi, Aminah
PMID: 21399996
Journal: Int J Obes (Lond). 2012 Feb;36(2):273-80.
Title: Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice.
Author: Park, S-Y|Kim, J-S|Seo, Y-R|Sung, M-K
PMID: 21544082
Journal: J Cell Physiol. 2012 Mar;227(3):1114-22.
Title: Stromal cell-derived factor-1/CXC receptor 4 and beta1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells.
Author: Huang, Wen-Shih|Chin, Chih-Chien|Chen, Cheng-Nan|Kuo, Yi-Hung|Chen, Te-Chuan|Yu, Hong-Ren|Tung, Shui-Yi|Shen, Chien-Heng|Hsieh, Yung-Yu|Guo, Su-Er|Shi, Chung-Sheng|Liu, Ta-Ju|Kuo, Hsing-Chun
PMID: 21567400
Journal: Br J Pharmacol. 2012 Feb;165(4b):1084-96.
Title: Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2.
Author: Lai, Li|Liu, Junchen|Zhai, Dong|Lin, Qingxiang|He, Lijun|Dong, Yanmin|Zhang, Jing|Lu, Binbin|Chen, Yihua|Yi, Zhengfang|Liu, Mingyao
PMID: 21658027
Journal: Oncogene. 2012 Jan 19;31(3):376-89.
Title: Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis.
Author: Swaminathan, G|Cartwright, C A
PMID: 21685945
Journal: Pathol Oncol Res. 2012 Apr;18(2):191-9.
Title: Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFkappa-B pathway.
Author: Fauzee, Nilufer Jasmine Selimah|Li, Qiaozhuan|Wang, Ya-Lan|Pan, Juan
PMID: 21713600
Journal: J Cell Physiol. 2012 May;227(5):1891-8.
Title: The pro-apoptotic effect of quercetin in cancer cell lines requires ERbeta-dependent signals.
Author: Bulzomi, Pamela|Galluzzo, Paola|Bolli, Alessandro|Leone, Stefano|Acconcia, Filippo|Marino, Maria
PMID: 21732360
Journal: Oncogene. 2012 Mar 29;31(13):1623-35.
Title: MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.
Author: Oneyama, C|Morii, E|Okuzaki, D|Takahashi, Y|Ikeda, J|Wakabayashi, N|Akamatsu, H|Tsujimoto, M|Nishida, T|Aozasa, K|Okada, M
PMID: 21860426
Journal: Ann Surg Oncol. 2012 Jan;19(1):145-53.
Title: Overexpression of RhoGDI2 correlates with tumor progression and poor prognosis in colorectal carcinoma.
Author: Li, Xianzheng|Wang, Jianmei|Zhang, Xiaojing|Zeng, Yuanfeng|Liang, Li|Ding, Yanqing
PMID: 21861235
Journal: Int J Oncol. 2012 Jan;40(1):176-84.
Title: The effect of a dimeric Affibody molecule (ZEGFR:1907)2 targeting EGFR in combination with radiation in colon cancer cell lines.
Author: Haggblad Sahlberg, Sara|Spiegelberg, Diana|Lennartsson, Johan|Nygren, Peter|Glimelius, Bengt|Stenerlow, Bo
PMID: 21879255
Journal: Dig Dis Sci. 2012 Feb;57(2):371-80.
Title: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells.
Author: Chung, Cho-Yun|Park, Young-Lan|Song, Young-A|Myung, Eun|Kim, Kyu-Yeol|Lee, Gi-Hoon|Ki, Ho-Seok|Park, Kang-Jin|Cho, Sung-Bum|Lee, Wan-Sik|Jung, Young-Do|Kim, Kyung-Keun|Joo, Young-Eun
PMID: 21901254
Journal: Cell Biochem Biophys. 2012 Jan;62(1):47-54.
Title: Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer.
Author: Cui, Binbin|Tao, Ji|Yang, Yanmei
PMID: 21910030
Journal: Mol Carcinog. 2012 Nov;51(11):869-80.
Title: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author: Park, Heesook|Kim, Minhee|Kwon, Gyoo Taik|Lim, Do Young|Yu, Rina|Sung, Mi-Kyung|Lee, Ki Won|Daily, James W 3rd|Park, Jung Han Yoon
PMID: 21919080
Journal: Cell Biochem Biophys. 2012 Jan;62(1):229-35.
Title: USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway.
Author: Liu, Yan-Long|Jiang, Shi-Xiong|Yang, Yan-Mei|Xu, Hui|Liu, Jing-Lei|Wang, Xi-Shan
PMID: 21928107
Journal: Int J Cancer. 2012 Aug 15;131(4):813-20.
Title: Oncogenic PIK3CA mutations in colorectal cancers and polyps.
Author: Whitehall, Vicki L J|Rickman, Celestine|Bond, Catherine E|Ramsnes, Ingunn|Greco, Sonia A|Umapathy, Aarti|McKeone, Diane|Faleiro, Rebecca J|Buttenshaw, Ron L|Worthley, Daniel L|Nayler, Sam|Zhao, Zhen Zhen|Montgomery, Grant W|Mallitt, Kylie-Ann|Jass, Jeremy
PMID: 21932420
Journal: Oncogene. 2012 Jul 5;31(27):3277-86.
Title: p37delta is a new isoform of PI3K p110delta that increases cell proliferation and is overexpressed in tumors.
Author: Fransson, S|Uv, A|Eriksson, H|Andersson, M K|Wettergren, Y|Bergo, M|Ejeskar, K
PMID: 22020336
Journal: Free Radic Biol Med. 2012 Jan 1;52(1):151-9.
Title: Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells.
Author: Da Silva, Mathieu|Jaggers, Grayson K|Verstraeten, Sandra V|Erlejman, Alejandra G|Fraga, Cesar G|Oteiza, Patricia I
PMID: 22074817
Journal: Cancer Lett. 2012 Feb 1;315(1):78-85.
Title: Selenite induces apoptosis in colorectal cancer cells via AKT-mediated inhibition of beta-catenin survival axis.
Author: Luo, Hui|Yang, Yang|Huang, Fang|Li, Feng|Jiang, Qian|Shi, Kejian|Xu, Caimin
PMID: 22074856
Journal: Breast Cancer Res Treat. 2012 Jun;133(3):909-16.
Title: Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.
Author: Kim, Jin Cheon|Yu, Jong Han|Cho, Yoon Kyung|Jung, Choon Sik|Ahn, Sei Hyun|Gong, Gyungyub|Kim, Yong Sung|Cho, Dong-Hyung
PMID: 22076481
Journal: Oncol Rep. 2012 Feb;27(2):339-46.
Title: shRNA against CD44 inhibits cell proliferation, invasion and migration, and promotes apoptosis of colon carcinoma cells.
Author: Park, Yeon Sun|Huh, Jung Wook|Lee, Jae Hyuk|Kim, Hyeong Rok
PMID: 22076607
Journal: Int J Cancer. 2012 Aug 1;131(3):E190-203.
Title: Phosphatase of regenerating liver-3 promotes migration and invasion by upregulating matrix metalloproteinases-7 in human colorectal cancer cells.
Author: Lee, Su-Kyung|Han, Young-Min|Yun, Jieun|Lee, Chang Woo|Shin, Dae-Seop|Ha, Young-Ran|Kim, Jina|Koh, Jong Sung|Hong, Su-Hyung|Han, Dong Cho|Kwon, Byoung-Mog
PMID: 22131018
Journal: Int J Oncol. 2012 Apr;40(4):1251-8.
Title: Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications.
Author: Feng, Xiaoying|Aleem, Eiman|Lin, Yingbo|Axelson, Magnus|Larsson, Olle|Stromberg, Thomas
PMID: 22159423
Journal: Int J Colorectal Dis. 2012 Jul;27(7):861-8.
Title: COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines.
Author: Xie, Song-qiang|Zhang, Ya-hong|Li, Qian|Wang, Jian-hong|Li, Jing-hua|Zhao, Jin|Wang, Chao-jie
PMID: 22159752
Journal: J Cancer Res Clin Oncol. 2012 Mar;138(3):387-95.
Title: Possible predictors of histopathological response to neoadjuvant chemoradiotherapy for rectal cancer.
Author: Farkas, Robert|Pozsgai, Eva|Schally, Andrew V|Szigeti, Andras|Szigeti, Edit|Laszlo, Zoltan|Papp, Andras|Gomori, Eva|Mangel, Laszlo|Horvath, Peter O|Bellyei, Szabolcs
PMID: 22160161
Journal: Cancer Res. 2012 Feb 1;72(3):779-89.
Title: Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
Author: Yang, Hong|Higgins, Brian|Kolinsky, Kenneth|Packman, Kathryn|Bradley, William D|Lee, Richard J|Schostack, Kathleen|Simcox, Mary Ellen|Kopetz, Scott|Heimbrook, David|Lestini, Brian|Bollag, Gideon|Su, Fei
PMID: 22180495
Journal: J Cell Biochem. 2012 May;113(5):1733-43.
Title: Silibinin suppresses the maintenance of colorectal cancer stem-like cells by inhibiting PP2A/AKT/mTOR pathways.
Author: Wang, Jir-You|Chang, Chia-Chi|Chiang, Chao-Ching|Chen, Wei-Ming|Hung, Shih-Chieh
PMID: 22213051
Journal: Mol Cancer. 2012 Jan 4;11:1.
Title: Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Author: Hummon, Amanda B|Pitt, Jason J|Camps, Jordi|Emons, Georg|Skube, Susan B|Huppi, Konrad|Jones, Tamara L|Beissbarth, Tim|Kramer, Frank|Grade, Marian|Difilippantonio, Michael J|Ried, Thomas|Caplen, Natasha J
PMID: 22216762
Journal: Lipids. 2012 Apr;47(4):403-11.
Title: The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.
Author: Li, Nan|Bu, Xiaodong|Wu, Peng|Wu, Pingping|Huang, Peilin
PMID: 22218925
Journal: J Nutr Biochem. 2012 Oct;23(10):1302-13.
Title: Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model.
Author: Tang, Feng-Yao|Pai, Man-Hui|Chiang, En-Pei Isabel
PMID: 22221675
Journal: Handb Exp Pharmacol. 2012;(208):451-68.
Title: Muscarinic receptor agonists and antagonists: effects on cancer.
Author: Spindel, Eliot R
PMID: 22222710
Journal: J Mol Med (Berl). 2012 Aug;90(8):925-34.
Title: Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
Author: Aviello, Gabriella|Romano, Barbara|Borrelli, Francesca|Capasso, Raffaele|Gallo, Laura|Piscitelli, Fabiana|Di Marzo, Vincenzo|Izzo, Angelo A
PMID: 22231745
Journal: Int J Oncol. 2012 Apr;40(4):1267-76.
Title: Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells.
Author: de Albuquerque-Xavier, Ana Cristina|Bastos, Lilian Goncalves R|de Freitas, Julio Cesar Madureira Jr|Leve, Fernanda|de Souza, Waldemir Fernandez|de Araujo, Wallace Martins|Wanderley, Joao Luiz Mendes|Tanaka, Marcelo Neves|de Souza, Wanderley|Morgado-Diaz,
PMID: 22246348
Journal: J Natl Cancer Inst. 2012 Feb 8;104(3):228-39.
Title: Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
Author: Ihle, Nathan T|Byers, Lauren A|Kim, Edward S|Saintigny, Pierre|Lee, J Jack|Blumenschein, George R|Tsao, Anne|Liu, Suyu|Larsen, Jill E|Wang, Jing|Diao, Lixia|Coombes, Kevin R|Chen, Lu|Zhang, Shuxing|Abdelmelek, Mena F|Tang, Ximing|Papadimitrakopoulou, Vass
PMID: 22247021
Journal: Clin Cancer Res. 2012 Apr 15;18(8):2316-25.
Title: The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer.
Author: Shimizu, Toshio|Tolcher, Anthony W|Papadopoulos, Kyriakos P|Beeram, Muralidhar|Rasco, Drew W|Smith, Lon S|Gunn, Shelly|Smetzer, Leslie|Mays, Theresa A|Kaiser, Brianne|Wick, Michael J|Alvarez, Cathy|Cavazos, Aracely|Mangold, Gina L|Patnaik, Amita
PMID: 22261800
Journal: Cancer Res. 2012 Mar 15;72(6):1504-17.
Title: Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
Author: Zaytseva, Yekaterina Y|Rychahou, Piotr G|Gulhati, Pat|Elliott, Victoria A|Mustain, William C|O'Connor, Kathleen|Morris, Andrew J|Sunkara, Manjula|Weiss, Heidi L|Lee, Eun Y|Evers, B Mark
PMID: 22266115
Journal: BMC Gastroenterol. 2012 Jan 23;12:9.
Title: Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells.
Author: Lim, Do Young|Cho, Han Jin|Kim, Jongdai|Nho, Chu Won|Lee, Ki Won|Park, Jung Han Yoon
PMID: 22269172
Journal: Mol Ther. 2012 May;20(5):938-47.
Title: Soluble vascular endothelial growth factor decoy receptor FP3 exerts potent antiangiogenic effects.
Author: Yu, De-Chao|Lee, Jung-Sun|Yoo, Ji Young|Shin, Hyewon|Deng, Hongxin|Wei, Yuquan|Yun, Chae-Ok
PMID: 22273580
Journal: J Cell Biochem. 2012 Jun;113(6):2086-97.
Title: Inhibition of IGF-IR increases chemosensitivity in human colorectal cancer cells through MRP-2 promoter suppression.
Author: Shen, Ke|Cui, Daling|Sun, Liyun|Lu, Yanhua|Han, Mingquan|Liu, Jianwen
PMID: 22275271
Journal: J Med Chem. 2012 Mar 8;55(5):2078-88.
Title: Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, cytotoxic activity, and study of the mechanism of action.
Author: Andreani, Aldo|Granaiola, Massimiliano|Locatelli, Alessandra|Morigi, Rita|Rambaldi, Mirella|Varoli, Lucilla|Calonghi, Natalia|Cappadone, Concettina|Farruggia, Giovanna|Stefanelli, Claudio|Masotti, Lanfranco|Nguyen, Tam L|Hamel, Ernest|Shoemaker, Robert H
PMID: 22283430
Journal: Clin Colorectal Cancer. 2012 Jun;11(2):143-50.
Title: PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.
Author: Sood, Arjun|McClain, Danielle|Maitra, Radhashree|Basu-Mallick, Atrayee|Seetharam, Raviraja|Kaubisch, Andreas|Rajdev, Lakshmi|Mariadason, John M|Tanaka, Kathryn|Goel, Sanjay
PMID: 22285706
Journal: Biochem Biophys Res Commun. 2012 Feb 10;418(2):426-32.
Title: Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
Author: Guo, Zheng|Zhou, Yuning|Evers, B Mark|Wang, Qingding
PMID: 22285861
Journal: Biochem Pharmacol. 2012 May 1;83(9):1195-207.
Title: Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel.
Author: Doroshow, James H|Juhasz, Agnes|Ge, Yun|Holbeck, Susan|Lu, Jiamo|Antony, Smitha|Wu, Yongzhong|Jiang, Guojian|Roy, Krishnendu
PMID: 22305747
Journal: Int J Oncol. 2012 Mar;40(3):816-24.
Title: Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells.
Author: Izutani, Yasuyuki|Yogosawa, Shingo|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 22307336
Journal: Exp Cell Res. 2012 Apr 15;318(7):828-34.
Title: Salicylic acid induces apoptosis in colon carcinoma cells grown in-vitro: influence of oxygen and salicylic acid concentration.
Author: Zitta, Karina|Meybohm, Patrick|Bein, Berthold|Huang, Ying|Heinrich, Christin|Scholz, Jens|Steinfath, Markus|Albrecht, Martin
PMID: 22342953
Journal: Cancer Lett. 2012 Aug 28;321(2):187-94.
Title: The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells.
Author: Tavolari, Simona|Munarini, Alessandra|Storci, Gianluca|Laufer, Stefan|Chieco, Pasquale|Guarnieri, Tiziana
PMID: 22343320
Journal: Carcinogenesis. 2012 Apr;33(4):931-6.
Title: Role of IL-17A in the development of colitis-associated cancer.
Author: Hyun, Yil Sik|Han, Dong Soo|Lee, A Reum|Eun, Chang Soo|Youn, Jeehee|Kim, Ho-Youn
PMID: 22354874
Journal: J Biosci. 2012 Mar;37(1):91-101.
Title: Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway.
Author: Wang, Di|Chen, Jian|Chen, Hui|Duan, Zhi|Xu, Qimei|Wei, Meiyan|Wang, Lianghua|Zhong, Meizuo
PMID: 22357207
Journal: PLoS One. 2012;7(2):e31729.
Title: Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.
Author: Liu, Zhi|Xing, Mingzhao
PMID: 22359623
Journal: World J Gastroenterol. 2012 Feb 21;18(7):601-8.
Title: Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.
Author: Sipos, Ferenc|Galamb, Orsolya
PMID: 22363130
Journal: J Cell Physiol. 2012 Nov;227(11):3648-60.
Title: p38alpha MAPK mediates 17beta-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells.
Author: Hsu, Hsi-Hsien|Liu, Chung-Jung|Shen, Chia-Yao|Chen, Yi-Jyun|Chen, Li-Mien|Kuo, Wu-Hsien|Lin, Yueh-Min|Chen, Ray-Jade|Tsai, Chang-Hai|Tsai, Fuu-Jen|Huang, Chih-Yang
PMID: 22377968
Journal: Biochim Biophys Acta. 2012 Jun;1822(6):1004-18.
Title: Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/beta-catenin signaling.
Author: Serafino, Annalucia|Moroni, Noemi|Psaila, Rossana|Zonfrillo, Manuela|Andreola, Federica|Wannenes, Francesca|Mercuri, Luana|Rasi, Guido|Pierimarchi, Pasquale
PMID: 22387884
Journal: FASEB J. 2012 Jun;26(6):2446-56.
Title: The cellular apoptosis susceptibility CAS/CSE1L gene protects ovarian cancer cells from death by suppressing RASSF1C.
Author: Lorenzato, Annalisa|Martino, Cosimo|Dani, Nadia|Oligschlager, Yvonne|Ferrero, Anna Maria|Biglia, Nicoletta|Calogero, Raffaele|Olivero, Martina|Di Renzo, Maria Flavia
PMID: 22389439
Journal: Mol Cancer Ther. 2012 Jun;11(6):1353-64.
Title: The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models.
Author: Ning, Yan|Labonte, Melissa J|Zhang, Wu|Bohanes, Pierre O|Gerger, Armin|Yang, Dongyun|Benhaim, Leonor|Paez, David|Rosenberg, David O|Nagulapalli Venkata, Kalyan C|Louie, Stan G|Petasis, Nicos A|Ladner, Robert D|Lenz, Heinz-Josef
PMID: 22391039
Journal: Biomed Pharmacother. 2012 Jul;66(5):354-67.
Title: Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/beta-catenin signaling.
Author: Vaish, Vivek|Sanyal, Sankar Nath
PMID: 22397759
Journal: Gastroenterology. 2012 Jun;142(7):1504-15.e3.
Title: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.
Author: Din, Farhat V N|Valanciute, Asta|Houde, Vanessa P|Zibrova, Daria|Green, Kevin A|Sakamoto, Kei|Alessi, Dario R|Dunlop, Malcolm G
PMID: 22406476
Journal: J Agric Food Chem. 2012 Apr 4;60(13):3441-51.
Title: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.
Author: Chiou, Yi-Shiou|Ma, Nianhan Jia-Lin|Sang, Shengmin|Ho, Chi-Tang|Wang, Ying-Jan|Pan, Min-Hsiung
PMID: 22409325
Journal: Br J Cancer. 2012 Apr 10;106(8):1386-94.
Title: The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.
Author: Haagensen, E J|Kyle, S|Beale, G S|Maxwell, R J|Newell, D R
PMID: 22415236
Journal: Onco Targets Ther. 2012;5:21-9.
Title: Emerging treatment options for the treatment of neuroblastoma: potential role of perifosine.
Author: Sun, Weili|Modak, Shakeel
PMID: 22419878
Journal: Int J Cancer. 2012 Dec 1;131(11):2487-98.
Title: Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro.
Author: Chen, Min-Bin|Wu, Xiao-Yang|Tao, Guo-Qing|Liu, Chao-Ying|Chen, Jian|Wang, Li-Qiang|Lu, Pei-Hua
PMID: 22438101
Journal: Phytomedicine. 2012 Jun 15;19(8-9):756-62.
Title: Triptolide inhibits colon-rectal cancer cells proliferation by induction of G1 phase arrest through upregulation of p21.
Author: Liu, Juanjuan|Shen, Min|Yue, Zhenggang|Yang, Zhifu|Wang, Meng|Li, Chen|Xin, Chunyan|Wang, Yukun|Mei, Qibing|Wang, Zhipeng
PMID: 22464014
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
PMID: 22465936
Journal: Int J Oncol. 2012 Jul;41(1):317-24.
Title: ErbB3 expression predicts sensitivity to elisidepsin treatment: in vitro synergism with cisplatin, paclitaxel and gemcitabine in lung, breast and colon cancer cell lines.
Author: Teixido, Cristina|Arguelaguet, Elisabet|Pons, Berta|Aracil, Miguel|Jimeno, Jose|Somoza, Rosa|Mares, Roso|Ramon Y Cajal, Santiago|Hernandez-Losa, Javier
PMID: 22485250
Journal: J Transl Med. 2012 Apr 10;10:71.
Title: Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab.
Author: Scartozzi, Mario|Giampieri, Riccardo|Maccaroni, Elena|Mandolesi, Alessandra|Biagetti, Simona|Alfonsi, Simona|Giustini, Lucio|Loretelli, Cristian|Faloppi, Luca|Bittoni, Alessandro|Bianconi, Maristella|Del Prete, Michela|Bearzi, Italo|Cascinu, Stefano
PMID: 22490361
Journal: PLoS One. 2012;7(4):e35378.
Title: The extra domain A of fibronectin increases VEGF-C expression in colorectal carcinoma involving the PI3K/AKT signaling pathway.
Author: Xiang, Lisha|Xie, Ganfeng|Ou, Juanjuan|Wei, Xing|Pan, Feng|Liang, Houjie
PMID: 22496919
Journal: Nutr Cancer. 2012;64(4):617-26.
Title: Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation.
Author: Saeki, Tohru|Yui, Satoko|Hirai, Tadashi|Fujii, Takami|Okada, Sawami|Kanamoto, Ryuhei
PMID: 22497644
Journal: Cancer Res. 2012 Jun 1;72(11):2780-90.
Title: High expression of IL-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.
Author: Barderas, Rodrigo|Bartolome, Ruben A|Fernandez-Acenero, Maria Jesus|Torres, Sofia|Casal, J Ignacio
PMID: 22505647
Journal: Cell Physiol Biochem. 2012;29(3-4):361-72.
Title: RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway.
Author: Li, Qiaozhuan|Li, Ming|Wang, Ya-Lan|Fauzee, Nilufer Jasmine Selimah|Yang, Yi|Pan, Juan|Yang, Lian|Lazar, Alexander
PMID: 22508044
Journal: Expert Opin Drug Metab Toxicol. 2012 May;8(5):623-33.
Title: Perifosine , an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity.
Author: Richardson, Paul G|Eng, Cathy|Kolesar, Jill|Hideshima, Teru|Anderson, Kenneth C
PMID: 22512706
Journal: Nutr Cancer. 2012;64(4):559-68.
Title: Ras signaling pathway in the chemopreventive action of different ratios of fish oil and corn oil in experimentally induced colon carcinogenesis.
Author: Kansal, S|Negi, A K|Bhatnagar, A|Agnihotri, N
PMID: 22519408
Journal: J Surg Res. 2012 Nov;178(1):233-41.
Title: Nicotine stimulates proliferation and inhibits apoptosis in colon cancer cell lines through activation of survival pathways.
Author: Cucina, Alessandra|Dinicola, Simona|Coluccia, Pierpaolo|Proietti, Sara|D'Anselmi, Fabrizio|Pasqualato, Alessia|Bizzarri, Mariano
PMID: 22520577
Journal: J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):280-286.
Title: Down-regulation of p110beta expression increases chemosensitivity of colon cancer cell lines to oxaliplatin.
Author: Liu, Weicheng|Wang, Guihua|Cao, Xiaonian|Luo, Xuelai|Li, Zhaoming|Deng, Yu|Li, Xiaolan|Wang, Shijia|Liu, Mengfei|Hu, Junbo|Wang, Jing
PMID: 22528234
Journal: PLoS One. 2012;7(4):e35123.
Title: GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.
Author: Chang, Yu-Jia|Huang, Yi-Ping|Li, Zih-Ling|Chen, Ching-Hsein
PMID: 22529978
Journal: Oncol Rep. 2012 Jul;28(1):15-20.
Title: Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Author: Li, Bo|Gao, Shuohui|Wei, Feng|Bellail, Anita C|Hao, Chunhai|Liu, Tongjun
PMID: 22552366
Journal: Int J Oncol. 2012 Jul;41(1):211-8.
Title: CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion.
Author: Cho, Sang Hyuk|Park, Yeon Sun|Kim, Hun Jin|Kim, Chang Hyun|Lim, Sang Woo|Huh, Jung Wook|Lee, Jae Hyuk|Kim, Hyeong Rok
PMID: 22552741
Journal: Clin Cancer Res. 2012 May 1;18(9):2704-14.
Title: Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.
Author: Arcaroli, John J|Quackenbush, Kevin S|Powell, Rebecca W|Pitts, Todd M|Spreafico, Anna|Varella-Garcia, Marileila|Bemis, Lynne|Tan, Aik Choon|Reinemann, Jaclyn M|Touban, Basel M|Dasari, Arvind|Eckhardt, S Gail|Messersmith, Wells A
PMID: 22553375
Journal: BMC Cancer. 2012 May 3;12:164.
Title: Indirubin derivative E804 inhibits angiogenesis.
Author: Shin, Eun-Kyung|Kim, Jin-Kyung
PMID: 22554053
Journal: BMC Res Notes. 2012 Jul 10;5:214.
Title: Akt and phospholipase Cgamma are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin.
Author: Tomas, Nicola M|Masur, Kai|Piecha, Jonas C|Niggemann, Bernd|Zanker, Kurt S
PMID: 22554284
Journal: Exp Mol Pathol. 2012 Aug;93(1):135-46.
Title: PTEN regulates apoptotic cell death through PI3-K/Akt/GSK3beta signaling pathway in DMH induced early colon carcinogenesis in rat.
Author: Saini, Manpreet Kaur|Sanyal, Sankar Nath
PMID: 22561258
Journal: Curr Pharm Des. 2012;18(20):2901-13.
Title: Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors in cancer therapy: advances and perspectives.
Author: Xue, Mengzhu|Cao, Xianwen|Zhong, Ye|Kuang, Dong|Liu, Xiaofeng|Zhao, Zhenjiang|Li, Honglin
PMID: 22571659
Journal: Mol Cancer Ther. 2012 Aug;11(8):1789-98.
Title: Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K.
Author: Munck, Joanne M|Batey, Michael A|Zhao, Yan|Jenkins, Helen|Richardson, Caroline J|Cano, Celine|Tavecchio, Michele|Barbeau, Jody|Bardos, Julia|Cornell, Liam|Griffin, Roger J|Menear, Keith|Slade, Andrew|Thommes, Pia|Martin, Niall M B|Newell, David R|Smith, G
PMID: 22576130
Journal: Int J Oncol. 2012 Aug;41(2):583-8.
Title: Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases.
Author: Jin, Ketao|Lan, Huanrong|Cao, Feilin|Han, Na|Xu, Zhenzhen|Li, Guangliang|He, Kuifeng|Teng, Lisong
PMID: 22581265
Journal: Carcinogenesis. 2012 Sep;33(9):1726-35.
Title: Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3beta pathway in colon cancer.
Author: Kumar, Ashok|Pandurangan, Ashok K|Lu, Fang|Fyrst, Henrik|Zhang, Meng|Byun, Hoe-Sup|Bittman, Robert|Saba, Julie D
PMID: 22581840
Journal: Food Funct. 2012 Aug;3(8):844-52.
Title: Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway.
Author: Xavier, Cristina P R|Lima, Cristovao F|Fernandes-Ferreira, Manuel|Pereira-Wilson, Cristina
PMID: 22596086
Journal: Biochem J. 2012 Aug 15;446(1):23-36.
Title: Myostatin is a novel tumoral factor that induces cancer cachexia.
Author: Lokireddy, Sudarsanareddy|Wijesoma, Isuru Wijerupage|Bonala, Sabeera|Wei, Meng|Sze, Siu Kwan|McFarlane, Craig|Kambadur, Ravi|Sharma, Mridula
PMID: 22621320
Journal: Dig Dis Sci. 2012 Nov;57(11):2873-82.
Title: Deguelin, an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice.
Author: Kang, Hyoun Woo|Kim, Jung Mogg|Cha, Mi Yeon|Jung, Hyun Chae|Song, In Sung|Kim, Joo Sung
PMID: 22623043
Journal: Clin Colorectal Cancer. 2012 Dec;11(4):268-74.
Title: Multiplexed protein signal pathway mapping identifies patients with rectal cancer that responds to neoadjuvant treatment.
Author: Mammano, Enzo|Galdi, Francesca|Pierobon, Mariaelena|Tessari, Emanuela|Deng, Jianghong|Pucciarelli, Salvatore|Agostini, Marco|De Marchi, Francesco|Canzonieri, Vincenzo|De Paoli, Antonino|Belluco, Claudio|Liotta, Lance|Petricoin, Emanuel|Pilati, Pierluigi|N
PMID: 22658458
Journal: BMC Cancer. 2012 Jun 6;12:221.
Title: Transforming growth factor-beta suppresses metastasis in a subset of human colon carcinoma cells.
Author: Simms, Neka A K|Rajput, Ashwani|Sharratt, Elizabeth A|Ongchin, Melanie|Teggart, Carol A|Wang, Jing|Brattain, Michael G
PMID: 22672900
Journal: PLoS One. 2012;7(5):e38033.
Title: KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors.
Author: Garrido-Laguna, Ignacio|Hong, David S|Janku, Filip|Nguyen, Ly M|Falchook, Gerald S|Fu, Siqing|Wheler, Jenifer J|Luthra, Rajyalakshmi|Naing, Aung|Wang, Xuemei|Kurzrock, Razelle
PMID: 22675430
Journal: Gastroenterology. 2012 Sep;143(3):741-53.e1-4.
Title: Obesity-induced increase in tumor necrosis factor-alpha leads to development of colon cancer in mice.
Author: Flores, Marcelo B S|Rocha, Guilherme Z|Damas-Souza, Danilo M|Osorio-Costa, Felipe|Dias, Marilia M|Ropelle, Eduardo R|Camargo, Juliana A|de Carvalho, Rita B|Carvalho, Hernandes F|Saad, Mario J A|Carvalheira, Jose B C
PMID: 22677195
Journal: Biol Pharm Bull. 2012;35(6):924-32.
Title: Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia-inducible factor-1alpha activation.
Author: Thapa, Dinesh|Kang, Youra|Park, Pil-Hoon|Noh, Seok Kyun|Lee, Yong Rok|Han, Sung Soo|Ku, Sae Kwang|Jung, Yunjin|Kim, Jung-Ae
PMID: 22687485
Journal: Carcinogenesis. 2012 Sep;33(9):1782-90.
Title: Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Author: Gulhati, Pat|Zaytseva, Yekaterina Y|Valentino, Joseph D|Stevens, Payton D|Kim, Ji Tae|Sasazuki, Takehiko|Shirasawa, Senji|Lee, Eun Y|Weiss, Heidi L|Dong, Jianli|Gao, Tianyan|Evers, B Mark
PMID: 22696593
Journal: Lung Cancer. 2012 Sep;77(3):593-9.
Title: Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer.
Author: Hu, Jing|Liu, Yan-Long|Piao, Song-lin|Yang, Dong-dong|Yang, Yan-Mei|Cai, Li
PMID: 22717106
Journal: Cell Signal. 2012 Oct;24(10):1940-9.
Title: ESM-1 regulates cell growth and metastatic process through activation of NF-kappaB in colorectal cancer.
Author: Kang, Yun Hee|Ji, Na Young|Han, Seung Ro|Lee, Chung Il|Kim, Jae Wha|Yeom, Young Il|Kim, Young Ho|Chun, Ho Kyung|Kim, Jong Wan|Chung, Jin Woong|Ahn, Dong Kuk|Lee, Hee Gu|Song, Eun Young
PMID: 22735811
Journal: Mol Cancer Ther. 2012 Sep;11(9):1884-93.
Title: Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the betaGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo.
Author: Mallucci, Livio|Shi, Dong-yun|Davies, Derek|Jordan, Peter|Nicol, Alastair|Lotti, Lavinia|Mariani-Costantini, Renato|Verginelli, Fabio|Wells, Valerie|Zicha, Daniel
PMID: 22752425
Journal: Anticancer Res. 2012 Jul;32(7):2537-43.
Title: Impact of Yangzheng Xiaoji on the adhesion and migration of human cancer cells: the role of the AKT signalling pathway.
Author: Ye, Lin|Ji, Ke|Frewer, Natasha|Ji, Jiafu|Jiang, Wen G
PMID: 22753711
Journal: Biol Pharm Bull. 2012;35(7):1054-63.
Title: (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation.
Author: Hong, Ji-Young|Boo, Hye-Jin|Kang, Jung-Il|Kim, Min-Kyoung|Yoo, Eun-Sook|Hyun, Jin-Won|Koh, Young-Sang|Kim, Gi Young|Maeng, Young Hee|Hyun, Chang Lim|Chang, Weon Young|Kim, Young Ho|Kim, Young Ree|Kang, Hee-Kyoung
PMID: 22791152
Journal: World J Gastroenterol. 2012 Jul 14;18(26):3458-64.
Title: Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948.
Author: Huang, Wen-Sheng|Wang, Tian-Bao|He, Yao|Chen, Yu-Jun|Zhong, Shi-Long|Tan, Min
PMID: 22807617
Journal: Surgery. 2012 Aug;152(2):277-85.
Title: Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer.
Author: Valentino, Joseph D|Elliott, Victoria A|Zaytseva, Yekaterina Y|Rychahou, Piotr G|Mustain, W Conan|Wang, Chi|Gao, Tianyan|Evers, B Mark
PMID: 22828149
Journal: Mol Cancer. 2012 Jul 25;11:46.
Title: Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model.
Author: Tsunoda, Toshiyuki|Ota, Takeharu|Fujimoto, Takahiro|Doi, Keiko|Tanaka, Yoko|Yoshida, Yasuhiro|Ogawa, Masahiro|Matsuzaki, Hiroshi|Hamabashiri, Masato|Tyson, Darren R|Kuroki, Masahide|Miyamoto, Shingo|Shirasawa, Senji
PMID: 22830422
Journal: Nutr Cancer. 2012 Aug;64(6):864-70.
Title: Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway.
Author: Li, Nan|Bu, Xiaodong|Tian, Xiaoqiang|Wu, Peng|Yang, Lin|Huang, Peilin
PMID: 22860766
Journal: Toxicol Sci. 2012 Dec;130(2):269-80.
Title: Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathway.
Author: Wang, Lei|Son, Young-Ok|Ding, Songze|Wang, Xin|Hitron, John Andrew|Budhraja, Amit|Lee, Jeong-Chae|Lin, Qinchen|Poyil, Pratheeshkumar|Zhang, Zhuo|Luo, Jia|Shi, Xianglin
PMID: 22872060
Journal: Int J Nanomedicine. 2012;7:4109-18.
Title: Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells.
Author: Fang, Lianghua|Chen, Baoan|Liu, Shenlin|Wang, Ruiping|Hu, Shouyou|Xia, Guohua|Tian, Yongli|Cai, Xiaohui
PMID: 22888247
Journal: Evid Based Complement Alternat Med. 2012;2012:871893.
Title: HRT, Herbal Formula, Induces G(2)/M Cell Cycle Arrest and Apoptosis via Suppressing Akt Signaling Pathway in Human Colon Cancer Cells.
Author: Yim, Nam-Hui|Cho, Won-Kyung|Lee, Ju Hye|Jung, Young Pil|Yang, Hye Jin|Ma, Jin Yeul
PMID: 22899960
Journal: PLoS One. 2012;7(8):e43158.
Title: The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.
Author: Sun, Jing|Sun, Quanhong|Brown, Matthew F|Dudgeon, Crissy|Chandler, Julie|Xu, Xiang|Shu, Yongqian|Zhang, Lin|Yu, Jian
PMID: 22912816
Journal: Mol Med Rep. 2012 Nov;6(5):1030-4.
Title: Adrenomedullin is involved in the progression of colonic adenocarcinoma.
Author: Kim, Jee-Youn|Park, Won-Do|Lee, Sun|Park, Jae-Hoon
PMID: 22923200
Journal: J Agric Food Chem. 2012 Sep 19;60(37):9430-6.
Title: In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids.
Author: He, Xiangjiu|Wang, Yihai|Hu, Hui|Zhang, Zhenxue
PMID: 22924395
Journal: Cell Prolif. 2012 Oct;45(5):413-9.
Title: EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis.
Author: Feng, Y|Dai, X|Li, X|Wang, H|Liu, J|Zhang, J|Du, Y|Xia, L
PMID: 22925500
Journal: Arch Pathol Lab Med. 2012 Sep;136(9):983-92.
Title: High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.
Author: Ney, Jasmin Teresa|Froehner, Stefanie|Roesler, Angelika|Buettner, Reinhard|Merkelbach-Bruse, Sabine
PMID: 22938585
Journal: Carcinogenesis. 2012 Dec;33(12):2538-47.
Title: Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner.
Author: Singh, Amar B|Sharma, Ashok|Dhawan, Punita
PMID: 22941059
Journal: Oncol Rep. 2012 Nov;28(5):1719-26.
Title: Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells.
Author: Ren, Jie|Cheng, Hong|Xin, Wen Qun|Chen, Xin|Hu, Kun
PMID: 22948973
Journal: Exp Cell Res. 2012 Dec 10;318(20):2548-58.
Title: A novel variant of the RON receptor tyrosine kinase derived from colorectal carcinoma cells which lacks tyrosine phosphorylation but induces cell migration.
Author: Wang, Da|Lao, Wei-Feng|Kuang, Ye-Ye|Geng, Shu-Min|Mo, Li-Juan|He, Chao
PMID: 22975341
Journal: Expert Opin Investig Drugs. 2012 Dec;21(12):1775-88.
Title: The promise of mTOR inhibitors in the treatment of colorectal cancer.
Author: Kim, Dae-Dong|Eng, Cathy
PMID: 22978346
Journal: Acta Pharmacol Sin. 2012 Dec;33(12):1441-58.
Title: PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes.
Author: Pal, Ipsita|Mandal, Mahitosh
PMID: 22983389
Journal: Carcinogenesis. 2012 Dec;33(12):2391-7.
Title: Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway.
Author: Iwaya, Takeshi|Yokobori, Takehiko|Nishida, Naohiro|Kogo, Ryunosuke|Sudo, Tomoya|Tanaka, Fumiaki|Shibata, Kohei|Sawada, Genta|Takahashi, Yusuke|Ishibashi, Masahisa|Wakabayashi, Go|Mori, Masaki|Mimori, Koshi
PMID: 22983984
Journal: Mol Cancer Ther. 2012 Nov;11(11):2311-20.
Title: Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage.
Author: Gierut, Jessica J|Mathur, Priya S|Bie, Wenjun|Han, Jin|Tyner, Angela L
PMID: 22989419
Journal: BMC Complement Altern Med. 2012 Sep 19;12:160.
Title: Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.
Author: Law, Pui-Ching|Auyeung, Kathy K|Chan, Lok-Yi|Ko, Joshua K
PMID: 22992293
Journal: Cell Cycle. 2012 Nov 1;11(21):3997-4008.
Title: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.
Author: Werneck, Miriam B F|Hottz, Eugenio|Bozza, Patricia T|Viola, Joao P B
PMID: 22992618
Journal: Mol Med Rep. 2012 Dec;6(6):1443-9.
Title: Antitumor actions of baicalein and wogonin in HT-29 human colorectal cancer cells.
Author: Kim, So-Jung|Kim, Hyeong-Jin|Kim, Hye-Ri|Lee, Seung-Ho|Cho, Sung-Dae|Choi, Chang-Sun|Nam, Jeong-Seok|Jung, Ji-Youn
PMID: 22992837
Journal: Am J Pathol. 2012 Nov;181(5):1847-61.
Title: Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.
Author: Yamamoto, Eiichiro|Suzuki, Hiromu|Yamano, Hiro-o|Maruyama, Reo|Nojima, Masanori|Kamimae, Seiko|Sawada, Takeshi|Ashida, Masami|Yoshikawa, Kenjiro|Kimura, Tomoaki|Takagi, Ryo|Harada, Taku|Suzuki, Ryo|Sato, Akiko|Kai, Masahiro|Sasaki, Yasushi|Tokino, Takashi
PMID: 22995252
Journal: World J Biol Chem. 2012 Sep 26;3(9):175-9.
Title: Nuclear accumulation of beta-catenin and forkhead box O3a in colon cancer: Dangerous liaison.
Author: Link, Wolfgang
PMID: 23024836
Journal: Curr Med Chem. 2012;19(33):5735-44.
Title: Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules.
Author: Efferth, T
PMID: 23033949
Journal: Cell Death Dis. 2012 Oct 11;3:e406.
Title: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
Author: Zhang, Y M|Dai, B L|Zheng, L|Zhan, Y Z|Zhang, J|Smith, W W|Wang, X L|Chen, Y N|He, L C
PMID: 23059825
Journal: Exp Ther Med. 2012 Jul;4(1):89-92.
Title: Effect of Jagged1 on the proliferation and migration of colon cancer cells.
Author: Tan, Yong|Peng, Jingjing|Wei, Dong|Chen, Peng|Zhao, Yu
PMID: 23060928
Journal: PLoS One. 2012;7(10):e44176.
Title: TLR-4 signalling accelerates colon cancer cell adhesion via NF-kappaB mediated transcriptional up-regulation of Nox-1.
Author: O'Leary, D Peter|Bhatt, Lavinia|Woolley, John F|Gough, David R|Wang, Jiang H|Cotter, Thomas G|Redmond, H Paul
PMID: 23071493
Journal: J Clin Invest. 2012 Nov;122(11):4077-93.
Title: Nanog signaling in cancer promotes stem-like phenotype and immune evasion.
Author: Noh, Kyung Hee|Kim, Bo Wook|Song, Kwon-Ho|Cho, Hanbyoul|Lee, Young-Ho|Kim, Jin Hee|Chung, Joon-Yong|Kim, Jae-Hoon|Hewitt, Stephen M|Seong, Seung-Yong|Mao, Chih-Ping|Wu, T-C|Kim, Tae Woo
PMID: 23093782
Journal: N Engl J Med. 2012 Oct 25;367(17):1596-606.
Title: Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
Author: Liao, Xiaoyun|Lochhead, Paul|Nishihara, Reiko|Morikawa, Teppei|Kuchiba, Aya|Yamauchi, Mai|Imamura, Yu|Qian, Zhi Rong|Baba, Yoshifumi|Shima, Kaori|Sun, Ruifang|Nosho, Katsuhiko|Meyerhardt, Jeffrey A|Giovannucci, Edward|Fuchs, Charles S|Chan, Andrew T|Ogino
PMID: 23094721
Journal: PLoS One. 2012;7(11):e47545.
Title: Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.
Author: Naito, Yutaka|Oue, Naohide|Hinoi, Takao|Sakamoto, Naoya|Sentani, Kazuhiro|Ohdan, Hideki|Yanagihara, Kazuyoshi|Sasaki, Hiroki|Yasui, Wataru
PMID: 23133598
Journal: Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title: [Predictive biomarkers for anti-EGFR antibodies].
Author: Bando, Hideaki|Yoshino, Takayuki
PMID: 23152013
Journal: Oncol Lett. 2012 Oct;4(4):763-766.
Title: The expression and clinical significance of PI3K, pAkt and VEGF in colon cancer.
Author: Zhang, Yinxu|Liu, Xiaomei|Zhang, Junhua|Li, Leiyu|Liu, Chunying
PMID: 23205098
Journal: Tumori. 2012 Sep-Oct;98(5):652-62.
Title: Expression of RON in colorectal cancer and its relationships with tumor cell behavior and prognosis.
Author: Park, Young-Lan|Lee, Gi-Hoon|Kim, Kyu-Yeol|Myung, Eun|Kim, Jong-Sun|Myung, Dae-Seong|Park, Kang-Jin|Cho, Sung-Bum|Lee, Wan-Sik|Jung, Young-Do|Kim, Hyun-Soo|Joo, Young-Eun
PMID: 23235762
Journal: Nihon Rinsho. 2012 Dec;70(12):2152-8.
Title: [Anti-EGFR antibody therapy for colorectal cancer].
Author: Ishikawa, Toshiaki|Uetake, Hiroyuki|Sugihara, Kenichi
PMID: 23259389
Journal: BMC Cancer. 2012 Dec 21;12:612.
Title: Alternative dosing of dual PI3K and MEK inhibition in cancer therapy.
Author: Jokinen, Elina|Laurila, Niina|Koivunen, Jussi P
PMID: 23259591
Journal: Asian Pac J Cancer Prev. 2012;13(11):5599-603.
Title: Mutational analysis of key EGFR pathway genes in Chinese breast cancer patients.
Author: Tong, Lin|Yang, Xue-Xi|Liu, Min-Feng|Yao, Guang-Yu|Dong, Jian-Yu|Ye, Chang-Sheng|Li, Ming
PMID: 23317280
Journal: Front Endocrinol (Lausanne). 2013 Jan 17;3:184.
Title: Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy.
Author: Wu, Zherui|Martinez-Fong, Daniel|Tredaniel, Jean|Forgez, Patricia
PMID: 23335914
Journal: Oncogene. 2013 Jan 10;32(2):234-41.
Title: Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer.
Author: Sun, H|Jiang, L|Luo, X|Jin, W|He, Q|An, J|Lui, K|Shi, J|Rong, R|Su, W|Lucchesi, C|Liu, Y|Sheikh, M S|Huang, Y
PMID: 22349814
Journal: Oncogene. 2013 Jan 24;32(4):471-8.
Title: The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.
Author: Li, X|Stevens, P D|Yang, H|Gulhati, P|Wang, W|Evers, B M|Gao, T
PMID: 22391563
Journal: Gut. 2013 Apr;62(4):550-60.
Title: Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling.
Author: De Boeck, Astrid|Pauwels, Patrick|Hensen, Karen|Rummens, Jean-Luc|Westbroek, Wendy|Hendrix, An|Maynard, Dawn|Denys, Hannelore|Lambein, Kathleen|Braems, Geert|Gespach, Christian|Bracke, Marc|De Wever, Olivier
PMID: 22535374
Journal: Invest New Drugs. 2013 Feb;31(1):1-13.
Title: Circulating vascular endothelial growth factor receptor 2/pAkt-positive cells as a functional pharmacodynamic marker in metastatic colorectal cancers treated with antiangiogenic agent.
Author: Shin, Sang Joon|Hwang, Jee Won|Ahn, Joong Bae|Rha, Sun Young|Roh, Jae Kyung|Chung, Hyun Cheol
PMID: 22539090
Journal: Oncogene. 2013 Apr 11;32(15):1910-20.
Title: MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer.
Author: Guo, S T|Jiang, C C|Wang, G P|Li, Y P|Wang, C Y|Guo, X Y|Yang, R H|Feng, Y|Wang, F H|Tseng, H-Y|Thorne, R F|Jin, L|Zhang, X D
PMID: 22710713
Journal: Oncogene. 2013 Apr 18;32(16):2087-95.
Title: Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14.
Author: Zhang, P|Guo, A|Possemato, A|Wang, C|Beard, L|Carlin, C|Markowitz, S D|Polakiewicz, R D|Wang, Z
PMID: 22710723
Journal: Hum Pathol. 2013 Feb;44(2):199-207.
Title: PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma.
Author: Abe, Azusa|Minaguchi, Takeo|Ochi, Hiroyuki|Onuki, Mamiko|Okada, Satoshi|Matsumoto, Koji|Satoh, Toyomi|Oki, Akinori|Yoshikawa, Hiroyuki
PMID: 22955107
Journal: Cell Signal. 2013 Jan;25(1):12-8.
Title: NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
Author: Eide, Peter W|Cekaite, Lina|Danielsen, Stine A|Eilertsen, Ina A|Kjenseth, Ane|Fykerud, Tone A|Agesen, Trude H|Bruun, Jarle|Rivedal, Edgar|Lothe, Ragnhild A|Leithe, Edward
PMID: 22974840
Journal: Antioxid Redox Signal. 2013 Apr 10;18(11):1249-62.
Title: Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.
Author: Saxena, Ashish|Tammali, Ravinder|Ramana, Kota V|Srivastava, Satish K
PMID: 22978663
Journal: Exp Mol Pathol. 2013 Feb;94(1):103-8.
Title: HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53.
Author: Ghosh, Anil|Lai, Cecilia|McDonald, Sarah|Suraweera, Nirosha|Sengupta, Neel|Propper, David|Dorudi, Sina|Silver, Andrew
PMID: 22982087
Journal: Int J Colorectal Dis. 2013 Mar;28(3):385-98.
Title: Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy.
Author: Wehler, Thomas C|Hamdi, Swaantje|Maderer, Annett|Graf, Claudine|Gockel, Ines|Schmidtmann, Irene|Hainz, Michael|Berger, Martin R|Theobald, Matthias|Galle, Peter R|Moehler, Markus|Schimanski, Carl C
PMID: 22983756
Journal: Cancer Lett. 2013 Jan 1;328(1):73-82.
Title: Celecoxib induces proliferation and Amphiregulin production in colon subepithelial myofibroblasts, activating erk1-2 signaling in synergy with EGFR.
Author: Benelli, Roberto|Vene, Roberta|Minghelli, Simona|Carlone, Sebastiano|Gatteschi, Beatrice|Ferrari, Nicoletta
PMID: 23010081
Journal: Food Chem. 2013 Jan 1;136(1):26-33.
Title: SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway.
Author: Son, Mi Kwon|Jung, Kyung Hee|Hong, Sang-Won|Lee, Hee-Seung|Zheng, Hong-Mei|Choi, Myung-Joo|Seo, Ju Hyeon|Suh, Jun-Kyu|Hong, Soon-Sun
PMID: 23017388
Journal: Oncogene. 2013 Sep 5;32(36):4304-12.
Title: Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Author: Zheng, Y|Gierut, J|Wang, Z|Miao, J|Asara, J M|Tyner, A L
PMID: 23027128
Journal: Clin Exp Metastasis. 2013 Mar;30(3):309-16.
Title: Protein pathway activation mapping of colorectal metastatic progression reveals metastasis-specific network alterations.
Author: Silvestri, Alessandra|Calvert, Valerie|Belluco, Claudio|Lipsky, Michael|De Maria, Ruggero|Deng, Jianghong|Colombatti, Alfonso|De Marchi, Francesco|Nitti, Donato|Mammano, Enzo|Liotta, Lance|Petricoin, Emanuel|Pierobon, Mariaelena
PMID: 23053743
Journal: Oncogene. 2013 Sep 12;32(37):4343-54.
Title: Mesenchymal stem cells promote growth and angiogenesis of tumors in mice.
Author: Huang, W-H|Chang, M-C|Tsai, K-S|Hung, M-C|Chen, H-L|Hung, S-C
PMID: 23085755
Journal: Int J Biochem Cell Biol. 2013 Feb;45(2):243-54.
Title: EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells.
Author: Ferraro, Angelo|Mourtzoukou, Despoina|Kosmidou, Vivian|Avlonitis, Spiros|Kontogeorgos, George|Zografos, George|Pintzas, Alexander
PMID: 23116973
Journal: Oncol Rep. 2013 Jan;29(1):349-54.
Title: Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells.
Author: Jia, Shu-Sheng|Xi, Guang-Peng|Zhang, Ming|Chen, Yan-Bo|Lei, Bo|Dong, Xin-Shu|Yang, Yan-Mei
PMID: 23117412
Journal: Oncol Rep. 2013 Feb;29(2):535-40.
Title: Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance.
Author: Li, Ang|Lu, Dehong|Zhang, Yupeng|Li, Jia|Fang, Yu|Li, Fei|Sun, Jiabang
PMID: 23165320
Journal: Phytother Res. 2013 Oct;27(10):1481-8.
Title: Raf and PI3K are the molecular targets for the anti-metastatic effect of luteolin.
Author: Kim, Ho Young|Jung, Sung Keun|Byun, Sanguine|Son, Joe Eun|Oh, Mi Hyun|Lee, Jihoon|Kang, Min Jeong|Heo, Yong-Seok|Lee, Ki Won|Lee, Hyong Joo
PMID: 23172826
Journal: Int J Oncol. 2013 Jan;42(1):219-28.
Title: MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells.
Author: Xiong, Binghong|Cheng, Yong|Ma, Li|Zhang, Caiquan
PMID: 23174819
Journal: Cancer Sci. 2013 Mar;104(3):328-36.
Title: Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes.
Author: Iwasaki, Hironori|Nakano, Kenji|Shinkai, Kentaro|Kunisawa, Yumi|Hirahashi, Minako|Oda, Yoshinao|Onishi, Hideya|Katano, Mitsuo
PMID: 23176625
Journal: Cancer Res. 2013 Jan 15;73(2):583-94.
Title: Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Author: Baker, Ann-Marie|Bird, Demelza|Welti, Jonathan C|Gourlaouen, Morgane|Lang, Georgina|Murray, Graeme I|Reynolds, Andrew R|Cox, Thomas R|Erler, Janine T
PMID: 23188504
Journal: Tumour Biol. 2013 Apr;34(2):683-93.
Title: Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.
Author: Ding, Zhen-Yu|Liu, Gui-Hong|Olsson, Birgit|Sun, Xiao-Feng
PMID: 23188704
Journal: J Biol Chem. 2013 Jan 25;288(4):2403-13.
Title: Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines.
Author: Vartanian, Steffan|Bentley, Carolyn|Brauer, Matthew J|Li, Li|Shirasawa, Senji|Sasazuki, Takehiko|Kim, Jung-Sik|Haverty, Pete|Stawiski, Eric|Modrusan, Zora|Waldman, Todd|Stokoe, David
PMID: 23188824
Journal: Biochim Biophys Acta. 2013 Feb;1829(2):239-47.
Title: Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1.
Author: Yin, Yu|Yan, Zhi-Ping|Lu, Na-Na|Xu, Qing|He, Jun|Qian, Xu|Yu, Jing|Guan, Xin|Jiang, Bing-Hua|Liu, Ling-Zhi
PMID: 23201159
Journal: Gastroenterology. 2013 Mar;144(3):624-635.e4.
Title: MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.
Author: Liang, Li|Li, Xianzheng|Zhang, Xiaojing|Lv, Zhenbing|He, Guoyang|Zhao, Wei|Ren, Xiaoli|Li, Yuling|Bian, Xiuwu|Liao, Wenting|Liu, Wei|Yang, Guangying|Ding, Yanqing
PMID: 23201162
Journal: Int J Oncol. 2013 Feb;42(2):556-64.
Title: Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition.
Author: Tanahashi, Toshiyuki|Osada, Shinji|Yamada, Atsuko|Kato, Junko|Yawata, Kazunori|Mori, Ryutaro|Imai, Hisashi|Sasaki, Yoshiyuki|Saito, Shiro|Tanaka, Yoshihiro|Nonaka, Kenichi|Yoshida, Kazuhiro
PMID: 23229794
Journal: Mol Cancer Res. 2013 Feb;11(2):109-21.
Title: Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author: Tabusa, Hana|Brooks, Teresa|Massey, Andrew J
PMID: 23233484
Journal: Clin Cancer Res. 2013 Feb 1;19(3):657-67.
Title: Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Author: Mao, Muling|Tian, Feng|Mariadason, John M|Tsao, Chun C|Lemos, Robert Jr|Dayyani, Farshid|Gopal, Y N Vashisht|Jiang, Zhi-Qin|Wistuba, Ignacio I|Tang, Xi M|Bornman, William G|Bollag, Gideon|Mills, Gordon B|Powis, Garth|Desai, Jayesh|Gallick, Gary E|Davies,
PMID: 23251002
Journal: J Pharmacol Sci. 2013;121(1):17-24. Epub 2012 Dec 26.
Title: Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.
Author: Niu, Mingshan|Sun, Yan|Liu, Xuejiao|Tang, Li|Qiu, Rongguo
PMID: 23269238
Journal: Int J Cancer. 2013 Jul;133(1):43-57.
Title: Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.
Author: Basu Roy, Upal K|Henkhaus, Rebecca S|Loupakis, Fotios|Cremolini, Chiara|Gerner, Eugene W|Ignatenko, Natalia A
PMID: 23280667
Journal: Int J Colorectal Dis. 2013 Jul;28(7):933-40.
Title: SLIT2 inhibits cell migration in colorectal cancer through the AKT-GSK3beta signaling pathway.
Author: Chen, Wei-Feng|Gao, Wei-Dong|Li, Quan-Lin|Zhou, Ping-Hong|Xu, Mei-Dong|Yao, Li-Qing
PMID: 23314850
Journal: Food Chem Toxicol. 2013 May;55:424-33.
Title: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
Author: Park, Eun-Jung|Chung, Hwa-Jin|Park, Hyen Joo|Kim, Gi Dae|Ahn, Yong-Hyun|Lee, Sang Kook
PMID: 23333577
Journal: Oncol Rep. 2013 Apr;29(4):1623-8.
Title: Scutellaria barbata D. Don induces G1/S arrest via modulation of p53 and Akt pathways in human colon carcinoma cells.
Author: Wei, Lihui|Lin, Jiumao|Wu, Guangwen|Xu, Wei|Li, Huang|Hong, Zhenfeng|Peng, Jun
PMID: 23354912
Journal: Cancer Res. 2013 May 1;73(9):2806-16.
Title: Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice.
Author: Xu, Changxin|Reichert, Ethan C|Nakano, Tomoyuki|Lohse, Mariah|Gardner, Alison A|Revelo, Monica P|Topham, Matthew K|Stafforini, Diana M
PMID: 23361301
Journal: Cancer Sci. 2013 May;104(5):604-10.
Title: Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways.
Author: Zhang, Long|Ji, Qing|Liu, Xuan|Chen, Xingzhu|Chen, Zhaohua|Qiu, Yanyan|Sun, Jian|Cai, Jianfeng|Zhu, Huirong|Li, Qi
PMID: 23363445
Journal: Cell Physiol Biochem. 2013;31(1):113-22.
Title: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Author: Yan, Xin|Shen, Hua|Jiang, Hongjian|Hu, Dan|Wang, Jun|Wu, Xinqi
PMID: 23363659
Journal: PLoS One. 2013;8(1):e55298.
Title: APRIL induces tumorigenesis and metastasis of colorectal cancer cells via activation of the PI3K/Akt pathway.
Author: Wang, Guihua|Wang, Feng|Ding, Weifeng|Wang, Jingchun|Jing, Rongrong|Li, Haiquan|Wang, Xudong|Wang, Yueguo|Ju, Shaoqing|Wang, Huimin
PMID: 23383143
Journal: Cell Death Dis. 2013 Feb 7;4:e481.
Title: PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.
Author: Luo, H|Yang, Y|Duan, J|Wu, P|Jiang, Q|Xu, C
PMID: 23392169
Journal: Oncol Lett. 2013 Feb;5(2):483-488.
Title: Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells.
Author: Gu, Yu|Liu, Shen-Lin|Ju, Wen-Zheng|Li, Chang-Yin|Cao, Peng
PMID: 23420047
Journal: Anticancer Drugs. 2013 Jun;24(5):473-83.
Title: Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells.
Author: Kawahara, Satomi|Otsuji, Yoko|Nakamura, Mitsuhiro|Murakami, Masashi|Murate, Takashi|Matsunaga, Toshiyuki|Kanoh, Hiroyuki|Seishima, Mariko|Banno, Yoshiko|Hara, Akira
PMID: 23426175
Journal: Oncol Lett. 2013 Mar;5(3):756-760.
Title: Regulation of AKT gene expression by cisplatin.
Author: Zhang, Jun|Zhang, Ling-Li|Shen, Lei|Xu, Xi-Ming|Yu, Hong-Gang
PMID: 23426872
Journal: Mol Cancer Ther. 2013 May;12(5):598-609.
Title: Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth.
Author: Ponnurangam, Sivapriya|Standing, David|Rangarajan, Parthasarathy|Subramaniam, Dharmalingam
PMID: 23427297
Journal: Genet Med. 2013 Jul;15(7):517-27.
Title: Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID: 23429431
Journal: PLoS One. 2013;8(2):e56664.
Title: Epithelial-mesenchymal transition (EMT) induced by TNF-alpha requires AKT/GSK-3beta-mediated stabilization of snail in colorectal cancer.
Author: Wang, Hao|Wang, Hong-Sheng|Zhou, Bin-Hua|Li, Cui-Lin|Zhang, Fan|Wang, Xian-Feng|Zhang, Ge|Bu, Xian-Zhang|Cai, Shao-Hui|Du, Jun
PMID: 23431386
Journal: Int J Cancer. 2013 Sep 1;133(5):1234-46.
Title: Inhibition of the renin-angiotensin system improves physiological outcomes in mice with mild or severe cancer cachexia.
Author: Murphy, Kate T|Chee, Annabel|Trieu, Jennifer|Naim, Timur|Lynch, Gordon S
PMID: 23436228
Journal: Autophagy. 2013 May;9(5):697-713.
Title: Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
Author: Raina, Komal|Agarwal, Chapla|Wadhwa, Ritambhara|Serkova, Natalie J|Agarwal, Rajesh
PMID: 23445752
Journal: J Agric Food Chem. 2013 Mar 20;61(11):2811-9.
Title: P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo.
Author: Chen, Li-Ching|Lee, Wen-Sen
PMID: 23448150
Journal: Cancer Lett. 2013 Jul 10;335(1):9-18.
Title: Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.
Author: Seshacharyulu, Parthasarathy|Pandey, Poomy|Datta, Kaustubh|Batra, Surinder K
PMID: 23454242
Journal: Mol Cell Biol. 2013 May;33(9):1859-68.
Title: The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.
Author: Romano, David|Maccario, Helene|Doherty, Carolanne|Quinn, Niall P|Kolch, Walter|Matallanas, David
PMID: 23459937
Journal: PLoS One. 2013;8(3):e58055.
Title: Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole andrographolide derivatives.
Author: Dey, Sumit Kumar|Bose, Dipayan|Hazra, Abhijit|Naskar, Subhendu|Nandy, Abhishek|Munda, Rudra Narayan|Das, Subhadip|Chatterjee, Nabanita|Mondal, Nirup Bikash|Banerjee, Sukdeb|Saha, Krishna Das
PMID: 23472133
Journal: Int J Cancer. 2013 Aug 15;133(4):984-96.
Title: Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer.
Author: Kim, Areumnuri|Lee, Jung-Eun|Lee, Seung-Sook|Kim, Cherin|Lee, Sun-Joo|Jang, Won-Suk|Park, Sunhoo
PMID: 23475782
Journal: Anticancer Res. 2013 Mar;33(3):785-90.
Title: Inhibition of AKT in human pancreatic, renal and colorectal cancer cells by four cardiac hormones.
Author: Skelton, William P 4th|Skelton, Michelle|Vesely, David L
PMID: 23482745
Journal: Cell Physiol Biochem. 2013;31(2-3):209-18.
Title: miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma.
Author: Zhong, Ming|Bian, Zhengqian|Wu, Zhiyong
PMID: 23486085
Journal: Clin Cancer Res. 2013 May 1;19(9):2342-54.
Title: PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer.
Author: Khan, Mohammad W|Keshavarzian, Ali|Gounaris, Elias|Melson, Joshua E|Cheon, Eric C|Blatner, Nichole R|Chen, Zongmin E|Tsai, Fu-Nien|Lee, Goo|Ryu, Hyunji|Barrett, Terrence A|Bentrem, David J|Beckhove, Philipp|Khazaie, Khashayarsha
PMID: 23487439
Journal: Nanomedicine (Lond). 2013 Aug;8(8):1307-22.
Title: Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53.
Author: Satapathy, Shakti Ranjan|Mohapatra, Purusottam|Preet, Ranjan|Das, Dipon|Sarkar, Biplab|Choudhuri, Tathagata|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 23514434
Journal: PLoS One. 2013;8(3):e58089.
Title: Utilization of quantitative in vivo pharmacology approaches to assess combination effects of everolimus and irinotecan in mouse xenograft models of colorectal cancer.
Author: Bradshaw-Pierce, Erica L|Pitts, Todd M|Kulikowski, Gillian|Selby, Heather|Merz, Andrea L|Gustafson, Daniel L|Serkova, Natalie J|Eckhardt, S Gail|Weekes, Colin D
PMID: 23520486
Journal: Biochem Biophys Res Commun. 2013 Apr 19;433(4):420-5.
Title: Involvement of PI3K-AKT-mTOR pathway in protein kinase CKII inhibition-mediated senescence in human colon cancer cells.
Author: Park, Ji Hye|Kim, Jin Joo|Bae, Young-Seuk
PMID: 23523798
Journal: Cell Death Dis. 2013 Mar 28;4:e563.
Title: Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin alpha6beta4-dependent Akt, GSK-3beta, and HSF-1 in mesenchymal stem cells.
Author: Son, T W|Yun, S P|Yong, M S|Seo, B N|Ryu, J M|Youn, H Y|Oh, Y M|Han, H J
PMID: 23538444
Journal: BMC Cancer. 2013 Apr 1;13:169.
Title: High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
Author: Guedes, Joana G|Veiga, Isabel|Rocha, Patricia|Pinto, Pedro|Pinto, Carla|Pinheiro, Manuela|Peixoto, Ana|Fragoso, Maria|Raimundo, Ana|Ferreira, Paula|Machado, Manuela|Sousa, Nuno|Lopes, Paula|Araujo, Antonio|Macedo, Joana|Alves, Fernando|Coutinho, Camila|He
PMID: 23548132
Journal: PLoS One. 2013;8(3):e59380.
Title: The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.
Author: Allen, Joshua E|Gallant, Jean-Nicolas|Dicker, David T|Amin, Shantu|Irby, Rosalyn B|Sharma, Arun K|El-Deiry, Wafik S
PMID: 23555026
Journal: Peptides. 2013 Jun;44:127-34.
Title: Designer peptide antagonist of the leptin receptor with peripheral antineoplastic activity.
Author: Beccari, Serena|Kovalszky, Ilona|Wade, John D|Otvos, Laszlo Jr|Surmacz, Eva
PMID: 23567149
Journal: Dev Biol. 2013 Jun 15;378(2):122-40.
Title: APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression.
Author: Wang, Chenhui|Zhao, Rui|Huang, Pin|Yang, Fu|Quan, Zhenghui|Xu, Na|Xi, Rongwen
PMID: 23570874
Journal: PLoS One. 2013;8(4):e60821.
Title: MACC1 down-regulation inhibits proliferation and tumourigenicity of nasopharyngeal carcinoma cells through Akt/beta-catenin signaling pathway.
Author: Meng, Fengjiao|Li, Hui|Shi, Huijuan|Yang, Qingxu|Zhang, Fenfen|Yang, Yang|Kang, Lili|Zhen, Tiantian|Dai, Sujuan|Dong, Yu|Han, Anjia
PMID: 23573286
Journal: Neoplasma. 2013;60(4):364-72.
Title: Low-concentration capsaicin promotes colorectal cancer metastasis by triggering ROS production and modulating Akt/mTOR and STAT-3 pathways.
Author: Yang, J|Li, T Z|Xu, G H|Luo, B B|Chen, Y X|Zhang, T
PMID: 23581408
Journal: Biochem Biophys Res Commun. 2013 May 17;434(4):760-6.
Title: PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells.
Author: Liu, Jingyi|Liao, Yueling|Ma, Kewei|Wang, Yonglu|Zhang, Guoxiang|Yang, Rongcun|Deng, Jiong
PMID: 23583404
Journal: Exp Cell Res. 2013 Jun 10;319(10):1463-70.
Title: Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
Author: Benoit, Yannick D|Witherspoon, Mavee S|Laursen, Kristian B|Guezguez, Amel|Beausejour, Marco|Beaulieu, Jean-Francois|Lipkin, Steven M|Gudas, Lorraine J
PMID: 23588203
Journal: Int J Oncol. 2013 Jun;42(6):2134-40.
Title: Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse.
Author: Manne, Nandini D P K|Lima, M|Enos, R T|Wehner, P|Carson, J A|Blough, Eric
PMID: 23589074
Journal: Evid Based Complement Alternat Med. 2013;2013:974313.
Title: Activation of AMP-Activated Protein Kinase alpha and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells.
Author: Cho, Sung-Yun|Lee, Hyo-Jeong|Lee, Hyo-Jung|Jung, Deok-Beom|Kim, Hyunseok|Sohn, Eun Jung|Kim, Bonglee|Jung, Ji Hoon|Kwon, Byoung-Mog|Kim, Sung-Hoon
PMID: 23589723
Journal: Am J Surg. 2013 May;205(5):608-12; discussion 612.
Title: Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry.
Author: Gawlick, Ute|Lu, Kim C|Douthit, Miriam A|Diggs, Brian S|Schuff, Kathryn G|Herzig, Daniel O|Tsikitis, Vassiliki L
PMID: 23592171
Journal: Cell Signal. 2013 Aug;25(8):1711-9.
Title: Cell survival and metastasis regulation by Akt signaling in colorectal cancer.
Author: Agarwal, Ekta|Brattain, Michael G|Chowdhury, Sanjib
PMID: 23603750
Journal: Onco Targets Ther. 2013 Apr 16;6:403-9.
Title: Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21).
Author: Amini, Afshin|Ehteda, Anahid|Masoumi Moghaddam, Samar|Akhter, Javed|Pillai, Krishna|Morris, David Lawson
PMID: 23620673
Journal: J Surg Res. 2013 Oct;184(2):755-60.
Title: Restoration of PTEN activity decreases metastases in an orthotopic model of colon cancer.
Author: Chowdhury, Sanjib|Ongchin, Melanie|Wan, Guanghua|Sharratt, Elizabeth|Brattain, Michael G|Rajput, Ashwani
PMID: 23623571
Journal: Pol J Pathol. 2013 Apr;64(1):15-20.
Title: PTEN expression profiles in colorectal adenocarcinoma and its precancerous lesions.
Author: Waniczek, Dariusz|Snietura, Miroslaw|Mlynarczyk-Liszka, Joanna|Piglowski, Wojciech|Kopec, Agnieszka|Lange, Dariusz|Rudzki, Marek|Arendt, Jerzy
PMID: 23625595
Journal: Int J Cancer. 2013 Nov;133(9):2089-101.
Title: Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Author: Martinelli, Erika|Troiani, Teresa|D'Aiuto, Elena|Morgillo, Floriana|Vitagliano, Donata|Capasso, Anna|Costantino, Sarah|Ciuffreda, Loreta Pia|Merolla, Francesco|Vecchione, Loredana|De Vriendt, Veerle|Tejpar, Sabine|Nappi, Anna|Sforza, Vincenzo|Martini, Giu
PMID: 23629727
Journal: Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7.
Title: In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.
Author: Shima, Fumi|Yoshikawa, Yoko|Ye, Min|Araki, Mitsugu|Matsumoto, Shigeyuki|Liao, Jingling|Hu, Lizhi|Sugimoto, Takeshi|Ijiri, Yuichi|Takeda, Azusa|Nishiyama, Yuko|Sato, Chie|Muraoka, Shin|Tamura, Atsuo|Osoda, Tsutomu|Tsuda, Ken-ichiro|Miyakawa, Tomoya|Fukunis
PMID: 23630290
Journal: Mol Cell Endocrinol. 2013 Jul 15;374(1-2):101-7.
Title: Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways.
Author: Scheinman, Eyal J|Rostoker, Ran|Leroith, Derek
PMID: 23643895
Journal: Radiother Oncol. 2013 May;107(2):184-8.
Title: Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer.
Author: Buijsen, Jeroen|Lammering, Guido|Jansen, Rob L H|Beets, Geerard L|Wals, Jaap|Sosef, Meindert|Den Boer, Marien O|Leijtens, Jeroen|Riedl, Robert G|Theys, Jan|Lambin, Philippe
PMID: 23647753
Journal: Zhonghua Yi Xue Za Zhi. 2013 Feb 26;93(8):623-6.
Title: [Effects and mechanisms of phosphatidylinositol 3 kinase B signal pathway on colon cancer cell SW480].
Author: Ma, Dong-hua|Long, Teng|Wang, Ya-xu|Shu, Ning-bo|Bi, De-li
PMID: 23663347
Journal: Int J Oncol. 2013 Jul;43(1):141-50.
Title: Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells.
Author: Chen, Hui-Jye|Jiang, Yi-Lin|Lin, Chung-Ming|Tsai, Shih-Chang|Peng, Shu-Fen|Fushiya, Shinji|Hour, Mann-Jen|Yang, Jai-Sing
PMID: 23677180
Journal: PLoS One. 2013 May 16;8(5):e63695.
Title: FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer.
Author: Pelaez-Garcia, Alberto|Barderas, Rodrigo|Torres, Sofia|Hernandez-Varas, Pablo|Teixido, Joaquin|Bonilla, Felix|de Herreros, Antonio Garcia|Casal, J Ignacio
PMID: 23696849
Journal: Asian Pac J Cancer Prev. 2013;14(4):2201-5.
Title: Potential targets for prevention of colorectal cancer: a focus on PI3K/Akt/mTOR and Wnt pathways.
Author: Pandurangan, Ashok Kumar
PMID: 23725112
Journal: Lipids Health Dis. 2013 Jun 1;12:83.
Title: Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.
Author: Li, Nan|Lu, Heng|Chen, Chunyan|Bu, Xiaodong|Huang, Peilin
PMID: 23725225
Journal: Free Radic Biol Med. 2013 Oct;63:280-90.
Title: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author: Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
PMID: 23732517
Journal: PLoS One. 2013 May 30;8(5):e63872.
Title: Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
Author: Wang, Jingshu|Liu, Liqun|Qiu, Huijuan|Zhang, Xiaohong|Guo, Wei|Chen, Wangbing|Tian, Yun|Fu, Lingyi|Shi, Dingbo|Cheng, Jianding|Huang, Wenlin|Deng, Wuguo
PMID: 23737956
Journal: Clin Cancer Res. 2013 Jul 15;19(14):3987-95.
Title: Phase II study of everolimus in patients with metastatic colorectal adenocarcinoma previously treated with bevacizumab-, fluoropyrimidine-, oxaliplatin-, and irinotecan-based regimens.
Author: Ng, Kimmie|Tabernero, Josep|Hwang, Jimmy|Bajetta, Emilio|Sharma, Sunil|Del Prete, Salvatore A|Arrowsmith, Edward R|Ryan, David P|Sedova, Michaela|Jin, Jin|Malek, Kamel|Fuchs, Charles S
PMID: 23743569
Journal: Anticancer Drugs. 2013 Sep;24(8):781-91.
Title: Inhibition of angiogenesis: a novel antitumor mechanism of the herbal compound arctigenin.
Author: Gu, Yuan|Scheuer, Claudia|Feng, Dilu|Menger, Michael D|Laschke, Matthias W
PMID: 23744558
Journal: Biochem Pharmacol. 2013 Aug 1;86(3):361-77.
Title: Destruxins: fungal-derived cyclohexadepsipeptides with multifaceted anticancer and antiangiogenic activities.
Author: Dornetshuber-Fleiss, R|Heffeter, P|Mohr, T|Hazemi, P|Kryeziu, K|Seger, C|Berger, W|Lemmens-Gruber, R
PMID: 23747344
Journal: Mol Syst Biol. 2013;9:673.
Title: Network quantification of EGFR signaling unveils potential for targeted combination therapy.
Author: Klinger, Bertram|Sieber, Anja|Fritsche-Guenther, Raphaela|Witzel, Franziska|Berry, Leanne|Schumacher, Dirk|Yan, Yibing|Durek, Pawel|Merchant, Mark|Schafer, Reinhold|Sers, Christine|Bluthgen, Nils
PMID: 23752269
Journal: Int J Oncol. 2013 Aug;43(2):629-37.
Title: Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Author: Chen, Hui-Jye|Lin, Chung-Ming|Lee, Chao-Ying|Shih, Nai-Chen|Amagaya, Sakae|Lin, Yung-Chang|Yang, Jai-Sing
PMID: 23754208
Journal: Int J Oncol. 2013 Aug;43(2):431-8.
Title: Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells.
Author: Shiragami, Risa|Murata, Soichiro|Kosugi, Chihiro|Tezuka, Tohru|Yamazaki, Masato|Hirano, Atsushi|Yoshimura, Yukino|Suzuki, Masato|Shuto, Kiyohiko|Koda, Keiji
PMID: 23754252
Journal: Exp Cell Res. 2013 Aug 1;319(13):1913-21.
Title: Selenate induces epithelial-mesenchymal transition in a colorectal carcinoma cell line by AKT activation.
Author: Tsukamoto, Takanori|Hama, Susumu|Kogure, Kentaro|Tsuchiya, Hiroyuki
PMID: 23769801
Journal: J Nutr Biochem. 2013 Oct;24(10):1766-75.
Title: Apigenin up-regulates transgelin and inhibits invasion and migration of colorectal cancer through decreased phosphorylation of AKT.
Author: Chunhua, Li|Donglan, Lin|Xiuqiong, Fu|Lihua, Zhang|Qin, Fan|Yawei, Liu|Liang, Zhao|Ge, Wen|Linlin, Jing|Ping, Zeng|Kun, Li|Xuegang, Sun
PMID: 23773626
Journal: Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(9):773-9.
Title: Honokiol augments the anti-cancer effects of oxaliplatin in colon cancer cells.
Author: Hua, Hanju|Chen, Wenbin|Shen, Ling|Sheng, Qinsong|Teng, Lisong
PMID: 23786838
Journal: Carcinogenesis. 2013 Dec;34(12):2861-9.
Title: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
Author: Wu, Jinhua|Xie, Na|Xie, Ke|Zeng, Jun|Cheng, Lin|Lei, Yunlong|Liu, Yuan|Song, Linhong|Dong, Dandan|Chen, Yi|Zeng, Rui|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23803691
Journal: Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title: Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
Author: Giampieri, Riccardo|Scartozzi, Mario|Del Prete, Michela|Maccaroni, Elena|Bittoni, Alessandro|Faloppi, Luca|Bianconi, Maristella|Cecchini, Luca|Cascinu, Stefano
PMID: 23806981
Journal: BMC Cancer. 2013 Jul 1;13:321.
Title: Overexpression of peptide deformylase in breast, colon, and lung cancers.
Author: Randhawa, Harsharan|Chikara, Shireen|Gehring, Drew|Yildirim, Tuba|Menon, Jyotsana|Reindl, Katie M
PMID: 23815882
Journal: PLoS One. 2013 Jun 27;8(6):e67258.
Title: Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.
Author: Fang, Douglas D|Zhang, Cathy C|Gu, Yin|Jani, Jitesh P|Cao, Joan|Tsaparikos, Konstantinos|Yuan, Jing|Thiel, Melissa|Jackson-Fisher, Amy|Zong, Qing|Lappin, Patrick B|Hayashi, Tomoko|Schwab, Richard B|Wong, Anthony|John-Baptiste, Annette|Bagrodia, Shubha|Los
PMID: 23826249
Journal: Radiother Oncol. 2013 Jul;108(1):32-9.
Title: Double targeting of Survivin and XIAP radiosensitizes 3D grown human colorectal tumor cells and decreases migration.
Author: Hehlgans, Stephanie|Petraki, Chrysi|Reichert, Sebastian|Cordes, Nils|Rodel, Claus|Rodel, Franz
PMID: 23830189
Journal: Oncol Rep. 2013 Oct;30(4):1701-6.
Title: Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathways.
Author: Shen, Aling|Lin, Jiumao|Chen, Youqin|Lin, Wei|Liu, Liya|Hong, Zhenfeng|Sferra, Thomas J|Peng, Jun
PMID: 23843018
Journal: Clin Cancer Res. 2013 Sep 1;19(17):4662-72.
Title: microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.
Author: Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing
PMID: 23846336
Journal: Oncogene. 2013 Dec 5;32(49):5541-50.
Title: Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma.
Author: Wu, Q|Wang, H|Zhao, X|Shi, Y|Jin, M|Wan, B|Xu, H|Cheng, Y|Ge, H|Zhang, Y
PMID: 23851494
Journal: Oncotarget. 2013 Aug;4(8):1185-98.
Title: Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Author: Saturno, Grazia|Valenti, Melanie|De Haven Brandon, Alexis|Thomas, George V|Eccles, Suzanne|Clarke, Paul A|Workman, Paul
PMID: 23852390
Journal: Nutr Cancer. 2013;65(5):718-28.
Title: Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.
Author: Cordero-Herrera, Isabel|Martin, Maria Angeles|Bravo, Laura|Goya, Luis|Ramos, Sonia
PMID: 23859040
Journal: Pharm Biol. 2013 Dec;51(12):1508-14.
Title: Cleome arabica leaf extract has anticancer properties in human cancer cells.
Author: Tigrine, Chafia|Bulzomi, Pamela|Leone, Stefano|Bouriche, Hamama|Kameli, Abdelkarim|Marino, Maria
PMID: 23862683
Journal: Biochem Biophys Res Commun. 2013 Aug 16;438(1):97-102.
Title: Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation.
Author: Zhu, Houbao|Xu, Wangyang|Zhang, Hongxin|Liu, Jianbing|Xu, Haimin|Lu, Shunyuan|Dang, Suying|Kuang, Ying|Jin, Xiaolong|Wang, Zhugang
PMID: 23872115
Journal: Biochim Biophys Acta. 2013 Nov;1830(11):5142-56.
Title: Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation.
Author: Piplani, Honit|Rana, Chandan|Vaish, Vivek|Vaiphei, Kim|Sanyal, S N
PMID: 23872169
Journal: Clin Cancer Res. 2013 Sep 15;19(18):4961-71.
Title: Protein kinase C-delta-mediated recycling of active KIT in colon cancer.
Author: Park, Misun|Kim, Won Kyu|Song, Meiying|Park, Minhee|Kim, Hyunki|Nam, Hye Jin|Baek, Sung Hee|Kim, Hoguen
PMID: 23881925
Journal: BMC Complement Altern Med. 2013 Jul 24;13:189.
Title: Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells.
Author: Cho, Sung-Yun|Lee, Hyo-Jeong|Cho, Sun-Mi|Kim, Bonglee|Jung, Yeon Kwon|Kim, Sung-Hoon
PMID: 23883349
Journal: Asian Pac J Cancer Prev. 2013;14(6):3631-4.
Title: MicroRNA-451 inhibits growth of human colorectal carcinoma cells via downregulation of Pi3k/Akt pathway.
Author: Li, Hong-Yan|Zhang, Yan|Cai, Jian-Hui|Bian, Hong-Lei
PMID: 23886157
Journal: Cancer Discov. 2013 Oct;3(10):1156-71.
Title: PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.
Author: Tan, Jing|Li, Zhimei|Lee, Puay Leng|Guan, Peiyong|Aau, Mei Yee|Lee, Shuet Theng|Feng, Min|Lim, Cheryl Zihui|Lee, Eric Yong Jing|Wee, Zhen Ning|Lim, Yaw Chyn|Karuturi, R K Murthy|Yu, Qiang
PMID: 23887393
Journal: PLoS One. 2013 Jul 24;8(7):e68543.
Title: Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21.
Author: Roy, Sanchita|Yu, Yingjie|Padhye, Subhash B|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 23894315
Journal: Int J Oncol. 2013 Oct;43(4):1111-6.
Title: Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation.
Author: Malilas, Waraporn|Koh, Sang Seok|Kim, Seokho|Srisuttee, Ratakorn|Cho, Il-Rae|Moon, Jeong|Yoo, Hwa-Seung|Oh, Sangtaek|Johnston, Randal N|Chung, Young-Hwa
PMID: 23917355
Journal: Toxicol Appl Pharmacol. 2013 Nov 1;272(3):746-56.
Title: 3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/beta-catenin signaling cascades and reversal of epithelial-mesenchymal transition.
Author: Tsai, Jie-Heng|Hsu, Li-Sung|Lin, Chih-Li|Hong, Hui-Mei|Pan, Min-Hsiung|Way, Tzong-Der|Chen, Wei-Jen
PMID: 23921149
Journal: Cancer Chemother Pharmacol. 2013 Sep;72(3):683-97.
Title: Molecular and cytogenetic changes in multi-drug resistant cancer cells and their influence on new compounds testing.
Author: Podolski-Renic, Ana|Jadranin, Milka|Stankovic, Tijana|Bankovic, Jasna|Stojkovic, Sonja|Chiourea, Maria|Aljancic, Ivana|Vajs, Vlatka|Tesevic, Vele|Ruzdijic, Sabera|Gagos, Sarantis|Tanic, Nikola|Pesic, Milica
PMID: 23934261
Journal: Virchows Arch. 2013 Oct;463(4):509-23.
Title: Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis.
Author: Neumann, Jens|Wehweck, Laura|Maatz, Susanne|Engel, Jutta|Kirchner, Thomas|Jung, Andreas
PMID: 23934607
Journal: PLoS One. 2013 Jul 23;8(7):e68817.
Title: Genotype directed therapy in murine mismatch repair deficient tumors.
Author: Kucherlapati, Melanie H|Esfahani, Shadi|Habibollahi, Peiman|Wang, Junning|Still, Eric R|Bronson, Roderick T|Mahmood, Umar|Kucherlapati, Raju S
PMID: 23935891
Journal: Cancer Gene Ther. 2013 Sep;20(9):487-92.
Title: Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets.
Author: Yan, J|Li, M|Threadgill, M D|Wang, Y|Fu, W
PMID: 23949281
Journal: J Nutr Biochem. 2013 Nov;24(11):1849-58.
Title: Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.
Author: Kumazaki, Minami|Noguchi, Shunsuke|Yasui, Yuki|Iwasaki, Junya|Shinohara, Haruka|Yamada, Nami|Akao, Yukihiro
PMID: 23954321
Journal: Cancer Chemother Pharmacol. 2013 Oct;72(4):767-75.
Title: Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells.
Author: Zhang, Guanzhong|Xie, Xiaodong|Liu, Tianyi|Yang, Jihua|Jiao, Shunchang
PMID: 23959460
Journal: Chem Pharm Bull (Tokyo). 2013;61(11):1149-55. Epub 2013 Aug 27.
Title: Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells.
Author: Zhou, Dai-Ying|Zhang, Kun|Conney, Allan H|Ding, Ning|Cui, Xiao-Xing|Wang, Hui|Verano, Michael|Zhao, Su-Qing|Fan, Yan-Xiong|Zheng, Xi|Du, Zhi-Yun
PMID: 23985704
Journal: PLoS One. 2013 Aug 22;8(8):e73175.
Title: Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma.
Author: Wang, Quan|Wei, Feng|Li, Chunsheng|Lv, Guoyue|Wang, Guangyi|Liu, Tongjun|Bellail, Anita C|Hao, Chunhai
PMID: 23991179
Journal: Carcinogenesis. 2013 Dec;34(12):2814-22.
Title: Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.
Author: Banerjee, Nivedita|Kim, Hyemee|Talcott, Stephen|Mertens-Talcott, Susanne
PMID: 23996930
Journal: PLoS One. 2013 Sep 4;8(9):e73151.
Title: Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.
Author: Drago, Eric|Bordonaro, Michael|Lee, Seon|Atamna, Wafa|Lazarova, Darina L
PMID: 24023824
Journal: Med Oncol. 2013 Dec;30(4):724.
Title: High level of p37delta-mRNA relative to p110delta-mRNA in neuroblastoma tumors correlates with poor patient survival.
Author: Fransson, Susanne|Ejeskar, Katarina
PMID: 24026661
Journal: Biochem Pharmacol. 2013 Nov 15;86(10):1419-29.
Title: Identification of novel small compounds that restore E-cadherin expression and inhibit tumor cell motility and invasiveness.
Author: Hirano, Tamaki|Satow, Reiko|Kato, Asami|Tamura, Mana|Murayama, Yumi|Saya, Hideyuki|Kojima, Hirotatsu|Nagano, Tetsuo|Okabe, Takayoshi|Fukami, Kiyoko
PMID: 24035834
Journal: Int J Oncol. 2013 Nov;43(5):1666-74.
Title: Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways.
Author: Lin, Jiumao|Chen, Youqin|Wei, Lihui|Hong, Zhenfeng|Sferra, Thomas J|Peng, Jun
PMID: 24042330
Journal: Int J Oncol. 2013 Nov;43(5):1511-6.
Title: Oxidative stress induces proliferation of colorectal cancer cells by inhibiting RUNX3 and activating the Akt signaling pathway.
Author: Kang, Kyoung Ah|Kim, Ki Cheon|Bae, Suk Chul|Hyun, Jin Won
PMID: 24042352
Journal: Oncogenesis. 2013 Sep 16;2:e71.
Title: Epigenetic and genetic features of 24 colon cancer cell lines.
Author: Ahmed, D|Eide, P W|Eilertsen, I A|Danielsen, S A|Eknaes, M|Hektoen, M|Lind, G E|Lothe, R A
PMID: 24042735
Journal: Chemotherapy. 2013;59(2):112-20.
Title: Acidic pH of tumor microenvironment enhances cytotoxicity of the disulfiram/Cu2+ complex to breast and colon cancer cells.
Author: Navratilova, Jarmila|Hankeova, Tereza|Benes, Petr|Smarda, Jan
PMID: 24051574
Journal: Radiat Oncol. 2013 Sep 23;8:219.
Title: Combined effects of C225 and 125-iodine seed radiation on colorectal cancer cells.
Author: Liu, Jingjia|Wang, Hao|Qu, Ang|Li, Jinna|Zhao, Yong|Wang, Junjie
PMID: 24053278
Journal: PLoS One. 2013 Sep 19;8(9):e74994.
Title: Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling.
Author: de Souza, Waldemir F|Fortunato-Miranda, Natalia|Robbs, Bruno K|de Araujo, Wallace M|de-Freitas-Junior, Julio C|Bastos, Lilian G|Viola, Joao P B|Morgado-Diaz, Jose A
PMID: 24069372
Journal: Oncol Rep. 2013 Dec;30(6):2647-52.
Title: Antitumor effect of 1, 8-cineole against colon cancer.
Author: Murata, Soichiro|Shiragami, Risa|Kosugi, Chihiro|Tezuka, Tohru|Yamazaki, Masato|Hirano, Atsushi|Yoshimura, Yukino|Suzuki, Masato|Shuto, Kiyohiko|Ohkohchi, Nobuhiro|Koda, Keiji
PMID: 24085263
Journal: Cancer Res. 2013 Nov 15;73(22):6654-66.
Title: Intestinal GUCY2C prevents TGF-beta secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.
Author: Gibbons, Ahmara V|Lin, Jieru E|Kim, Gilbert W|Marszalowicz, Glen P|Li, Peng|Stoecker, Brian A|Blomain, Erik S|Rattan, Satish|Snook, Adam E|Schulz, Stephanie|Waldman, Scott A
PMID: 24085786
Journal: Mol Cancer Ther. 2013 Dec;12(12):2857-63.
Title: Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations.
Author: Ganesan, Prasanth|Janku, Filip|Naing, Aung|Hong, David S|Tsimberidou, Apostolia M|Falchook, Gerald S|Wheler, Jennifer J|Piha-Paul, Sarina A|Fu, Siqing|Stepanek, Vanda M|Lee, J Jack|Luthra, Rajyalakshmi|Overman, Michael J|Kopetz, E Scott|Wolff, Robert A|Ku
PMID: 24092809
Journal: Toxicol In Vitro. 2013 Dec;27(8):2256-63.
Title: Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs.
Author: Dinicola, Simona|Morini, Veronica|Coluccia, Pierpaolo|Proietti, Sara|D'Anselmi, Fabrizio|Pasqualato, Alessia|Masiello, Maria Grazia|Palombo, Alessandro|De Toma, Giorgio|Bizzarri, Mariano|Cucina, Alessandra
PMID: 24095863
Journal: PLoS One. 2013 Oct 1;8(10):e75292.
Title: CIP2A influences survival in colon cancer and is critical for maintaining Myc expression.
Author: Wiegering, Armin|Pfann, Christina|Uthe, Friedrich Wilhelm|Otto, Christoph|Rycak, Lukas|Mader, Uwe|Gasser, Martin|Waaga-Gasser, Anna-Maria|Eilers, Martin|Germer, Christoph-Thomas
PMID: 24098375
Journal: Int J Oncol. 2013 Dec;43(6):1992-8.
Title: Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells.
Author: Li, Xiu Juan|Leem, Sun-Hee|Park, Man Hee|Kim, Soo Mi
PMID: 24100865
Journal: J Clin Endocrinol Metab. 2013 Dec;98(12):E1909-17.
Title: Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Author: Yang, Qi|Ji, Meiju|Guan, Haixia|Shi, Bingyin|Hou, Peng
PMID: 24106286
Journal: Cancer Res. 2013 Nov 15;73(22):6584-96.
Title: Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis.
Author: Bramswig, Kira H|Poettler, Marina|Unseld, Matthias|Wrba, Friedrich|Uhrin, Pavel|Zimmermann, Wolfgang|Zielinski, Christoph C|Prager, Gerald W
PMID: 24121495
Journal: Mol Cancer Ther. 2013 Dec;12(12):2640-50.
Title: Apigenin sensitizes colon cancer cells to antitumor activity of ABT-263.
Author: Shao, Huanjie|Jing, Kai|Mahmoud, Esraa|Huang, Haihong|Fang, Xianjun|Yu, Chunrong
PMID: 24126433
Journal: Mol Cancer Ther. 2013 Dec;12(12):2782-91.
Title: ATP citrate lyase mediates resistance of colorectal cancer cells to SN38.
Author: Zhou, Yunfei|Bollu, Lakshmi Reddy|Tozzi, Federico|Ye, Xiangcang|Bhattacharya, Rajat|Gao, Guang|Dupre, Elizabeth|Xia, Ling|Lu, Jia|Fan, Fan|Bellister, Seth|Ellis, Lee M|Weihua, Zhang
PMID: 24132143
Journal: J Agric Food Chem. 2013 Nov 13;61(45):10730-40.
Title: Coumarins and lignans from Zanthoxylum schinifolium and their anticancer activities.
Author: Li, Wei|Sun, Ya Nan|Yan, Xi Tao|Yang, Seo Young|Kim, Eun-Ji|Kang, Hee Kyoung|Kim, Young Ho
PMID: 24144361
Journal: J Biol Chem. 2013 Nov 29;288(48):34545-54.
Title: WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).
Author: Gangula, Narmadha Reddy|Maddika, Subbareddy
PMID: 24145035
Journal: Nutr Cancer. 2013;65(7):1045-58.
Title: Anticarcinogenic effects of the ethanolic extract of Salix aegyptiaca in colon cancer cells: involvement of Akt/PKB and MAPK pathways.
Author: Enayat, Shabnam|Ceyhan, Muserref Seyma|Basaran, Arif Ahmet|Gursel, Mayda|Banerjee, Sreeparna
PMID: 24168160
Journal: Clin Cancer Res. 2013 Dec 15;19(24):6787-801.
Title: A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells.
Author: Puig, Isabel|Chicote, Irene|Tenbaum, Stephan P|Arques, Oriol|Herance, Jose Raul|Gispert, Juan D|Jimenez, Jose|Landolfi, Stefania|Caci, Karina|Allende, Helena|Mendizabal, Leire|Moreno, Debora|Charco, Ramon|Espin, Eloy|Prat, Aleix|Elez, Maria Elena|Argiles,
PMID: 24170545
Journal: BMC Cancer. 2013 Nov 4;13:521.
Title: The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
Author: Wang, Quan|Wei, Feng|Lv, Guoyue|Li, Chunsheng|Liu, Tongjun|Hadjipanayis, Costas G|Zhang, Guikai|Hao, Chunhai|Bellail, Anita C
PMID: 24182354
Journal: PLoS One. 2013 Oct 30;8(10):e78086.
Title: Proliferation of colorectal cancer is promoted by two signaling transduction expression patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK.
Author: Yao, Yong-Liang|Shao, Jie|Zhang, Chunfu|Wu, Jian-Hong|Zhang, Qing-Hui|Wang, Jian-Jun|Zhu, Wei
PMID: 24205104
Journal: J Natl Cancer Inst. 2013 Dec 4;105(23):1789-98.
Title: Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.
Author: Ogino, Shuji|Liao, Xiaoyun|Imamura, Yu|Yamauchi, Mai|McCleary, Nadine J|Ng, Kimmie|Niedzwiecki, Donna|Saltz, Leonard B|Mayer, Robert J|Whittom, Renaud|Hantel, Alexander|Benson, Al B 3rd|Mowat, Rex B|Spiegelman, Donna|Goldberg, Richard M|Bertagnolli, Monic
PMID: 24231454
Journal: J Clin Oncol. 2013 Dec 20;31(36):4562-8.
Title: Evaluating many treatments and biomarkers in oncology: a new design.
Author: Kaplan, Richard|Maughan, Timothy|Crook, Angela|Fisher, David|Wilson, Richard|Brown, Louise|Parmar, Mahesh
PMID: 24248692
Journal: World J Gastroenterol. 2013 Nov 14;19(42):7374-88.
Title: 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
Author: Das, Dipon|Preet, Ranjan|Mohapatra, Purusottam|Satapathy, Shakti Ranjan|Kundu, Chanakya Nath
PMID: 24259968
Journal: PLoS One. 2013 Nov 18;8(11):e80806.
Title: CD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growth.
Author: Camacho-Concha, Nohemi|Olivos-Ortiz, Amiel|Nunez-Rivera, Alfredo|Pedroza-Saavedra, Adolfo|Gutierrez-Xicotencatl, Lourdes|Rosenstein, Yvonne|Pedraza-Alva, Gustavo
PMID: 24260485
Journal: Sci Rep. 2013 Nov 25;3:3308.
Title: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer.
Author: Crociani, Olivia|Zanieri, Francesca|Pillozzi, Serena|Lastraioli, Elena|Stefanini, Matteo|Fiore, Antonella|Fortunato, Angelo|D'Amico, Massimo|Masselli, Marika|De Lorenzo, Emanuele|Gasparoli, Luca|Chiu, Martina|Bussolati, Ovidio|Becchetti, Andrea|Arcangeli,
PMID: 24270902
Journal: PLoS One. 2013 Nov 25;8(11):e81139.
Title: Cyclic phosphatidic acid stimulates cAMP production and inhibits growth in human colon cancer cells.
Author: Tsukahara, Tamotsu|Matsuda, Yoshikazu|Haniu, Hisao
PMID: 24282571
Journal: PLoS One. 2013 Nov 29;8(11):e81203.
Title: Down-regulation of miR-126 is associated with colorectal cancer cells proliferation, migration and invasion by targeting IRS-1 via the AKT and ERK1/2 signaling pathways.
Author: Zhou, Yu|Feng, Xiao|Liu, Ya-ling|Ye, Shi-cai|Wang, Hao|Tan, Wen-kai|Tian, Ting|Qiu, Yu-mei|Luo, He-sheng
PMID: 24312276
Journal: PLoS One. 2013 Nov 27;8(11):e81592.
Title: Anti-cancer activity of an osthole derivative, NBM-T-BMX-OS01: targeting vascular endothelial growth factor receptor signaling and angiogenesis.
Author: Yang, Hung-Yu|Hsu, Ya-Fen|Chiu, Pei-Ting|Ho, Shiau-Jing|Wang, Chi-Han|Chi, Chih-Chin|Huang, Yu-Han|Lee, Cheng-Feng|Li, Ying-Shiuan|Ou, George|Hsu, Ming-Jen
PMID: 24312323
Journal: Cancer Biol Ther. 2013 Dec;14(12):1075-6.
Title: Not all antibodies are equal.
Author: Booth, Laurence
PMID: 24317328
Journal: Cell Physiol Biochem. 2013;32(6):1587-99.
Title: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-kappaB pathway.
Author: Xiao, Ming|Tang, Yi|Wang, Ya-Lan|Yang, Lian|Li, Xian|Kuang, Jing|Song, Guang-Lin
PMID: 24335275
Journal: PLoS One. 2013 Dec 10;8(12):e81763.
Title: The enhanced in vivo activity of the combination of a MEK and a PI3K inhibitor correlates with [18F]-FLT PET in human colorectal cancer xenograft tumour-bearing mice.
Author: Haagensen, Emma J|Thomas, Huw D|Wilson, Ian|Harnor, Suzannah J|Payne, Sara L|Rennison, Tommy|Smith, Kate M|Maxwell, Ross J|Newell, David R
PMID: 24339963
Journal: J Transl Med. 2013 Dec 17;11:313.
Title: TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer.
Author: Wei, Ping|Zhang, Nu|Xu, Ye|Li, Xinxiang|Shi, Debing|Wang, Yuwei|Li, Dawei|Cai, Sanjun
PMID: 24341487
Journal: PLoS One. 2013 Dec 20;8(12):e84815.
Title: The role of microRNA-200 in progression of human colorectal and breast cancer.
Author: Bojmar, Linda|Karlsson, Elin|Ellegard, Sander|Olsson, Hans|Bjornsson, Bergthor|Hallbook, Olof|Larsson, Marie|Stal, Olle|Sandstrom, Per
PMID: 24376848
Journal: Enzymes. 2013;34 Pt. B:1-23.
Title: Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras.GTP-effector interaction.
Author: Shima, Fumi|Yoshikawa, Yoko|Matsumoto, Shigeyuki|Kataoka, Tohru
PMID: 25034098
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E62-71.
Title: The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.
Author: Huang, John|Che, Mei-Ieng|Lin, Neng-Yu|Hung, Ji-Shiang|Huang, Yu-Ting|Lin, Wei-Chou|Huang, Hsiu-Chin|Lee, Po-Huang|Liang, Jin-Tung|Huang, Min-Chuan
PMID: 23390052
Journal: Oncogene. 2014 Mar 20;33(12):1538-47.
Title: Inactivation of TGF-beta signaling and loss of PTEN cooperate to induce colon cancer in vivo.
Author: Yu, M|Trobridge, P|Wang, Y|Kanngurn, S|Morris, S M|Knoblaugh, S|Grady, W M
PMID: 23604118
Journal: Oncogene. 2014 Apr 3;33(14):1828-39.
Title: ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer.
Author: Ye, Q|Cai, W|Zheng, Y|Evers, B M|She, Q-B
PMID: 23624914
Journal: Oncogene. 2014 Apr 17;33(16):2123-33.
Title: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author: Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J
PMID: 23644655
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E107-18.
Title: Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway.
Author: Wang, Hu|Zhao, Li|Zhu, Li-Tao|Wang, Yu|Pan, Di|Yao, Jing|You, Qi-Dong|Guo, Qing-Long
PMID: 23761018
Journal: Oncogene. 2014 Jun 5;33(23):2949-55.
Title: Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Author: Ogino, S|Lochhead, P|Giovannucci, E|Meyerhardt, J A|Fuchs, C S|Chan, A T
PMID: 23792451
Journal: Int J Colorectal Dis. 2014 Jan;29(1):31-41.
Title: Gefitinib enhances the effects of combined radiotherapy and 5-fluorouracil in a colorectal cancer cell line.
Author: Palumbo, Isabella|Piattoni, Simonetta|Valentini, Vincenzo|Marini, Valeria|Contavalli, Paola|Calzuola, Monica|Vecchio, Fabio Maria|Cecchini, Debora|Falzetti, Franca|Aristei, Cynthia
PMID: 23917393
Journal: Oncogene. 2014 Jul 10;33(28):3677-87.
Title: CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation.
Author: Nie, J|Liu, L|Xing, G|Zhang, M|Wei, R|Guo, M|Li, X|Xie, P|Li, L|He, F|Han, W|Zhang, L
PMID: 23995790
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E151-60.
Title: Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.
Author: Suman, Suman|Kurisetty, Vittal|Das, Trinath P|Vadodkar, Aditi|Ramos, Gabriel|Lakshmanaswamy, Rajkumar|Damodaran, Chendil
PMID: 24000138
Journal: Tumour Biol. 2014 Feb;35(2):871-9.
Title: Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesis.
Author: Uddin, Shahab|Hussain, Azhar R|Khan, Omar S|Al-Kuraya, Khawla S
PMID: 24014051
Journal: Horm Metab Res. 2014 Feb;46(2):85-93.
Title: Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells.
Author: Baricevic, I|Roberts, D L|Renehan, A G
PMID: 24068609
Journal: Mol Nutr Food Res. 2014 Mar;58(3):457-65.
Title: The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects.
Author: Romano, Barbara|Fasolino, Ines|Pagano, Ester|Capasso, Raffaele|Pace, Simona|De Rosa, Giuseppe|Milic, Natasa|Orlando, Pierangelo|Izzo, Angelo A|Borrelli, Francesca
PMID: 24123777
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E169-80.
Title: Reg4-induced mitogenesis involves Akt-GSK3beta-beta-Catenin-TCF-4 signaling in human colorectal cancer.
Author: Bishnupuri, Kumar S|Sainathan, Satheesh K|Bishnupuri, Kislay|Leahy, Devon R|Luo, Qizhi|Anant, Shrikant|Houchen, Courtney W|Dieckgraefe, Brian K
PMID: 24151146
Journal: Tumour Biol. 2014 Mar;35(3):2537-48.
Title: MACC1 is involved in the regulation of proliferation, colony formation, invasion ability, cell cycle distribution, apoptosis and tumorigenicity by altering Akt signaling pathway in human osteosarcoma.
Author: Zhang, Kai|Tian, Fang|Zhang, Yonggang|Zhu, Qing|Xue, Na|Zhu, Huimin|Wang, Heng|Guo, Xinjun
PMID: 24163085
Journal: Endocr Relat Cancer. 2013 Dec 20;21(1):73-84.
Title: GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction.
Author: Huang, Ssu-Ming|Chen, Tzu-Sheng|Chiu, Chien-Ming|Chang, Leang-Kai|Liao, Kuan-Fu|Tan, Hsiao-Ming|Yeh, Wei-Lan|Chang, Gary Ro-Lin|Wang, Min-Ying|Lu, Dah-Yuu
PMID: 24165321
Journal: Biochim Biophys Acta. 2014 Feb;1843(2):372-86.
Title: CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.
Author: Ellis, Blake C|Graham, Lloyd D|Molloy, Peter L
PMID: 24184209
Journal: Int J Oncol. 2014 Jan;44(1):203-10.
Title: MicroRNA-126 functions as a tumor suppressor in colorectal cancer cells by targeting CXCR4 via the AKT and ERK1/2 signaling pathways.
Author: Liu, Yaling|Zhou, Yu|Feng, Xiao|An, Ping|Quan, Xiaojing|Wang, Hao|Ye, Shicai|Yu, Caiyuan|He, Yanting|Luo, Hesheng
PMID: 24189753
Journal: Int J Mol Med. 2014 Jan;33(1):194-200.
Title: P7 peptides targeting bFGF sensitize colorectal cancer cells to CPT-11.
Author: Luo, Wu|Yu, Yonglin|Wang, Ruixue|He, Dan|Wang, Cong|Zeng, Xiangfeng|Chen, Xilei|Tan, Xiangpeng|Huang, Tao|Wu, Xiaoping
PMID: 24190390
Journal: Integr Cancer Ther. 2014 May;13(3):240-8.
Title: Scutellaria Barbata D Don Inhibits Colorectal Cancer Growth via Suppression of Multiple Signaling Pathways.
Author: Lin, Jiumao|Chen, Youqin|Cai, Qiaoyan|Wei, Lihui|Zhan, Youzhi|Shen, Aling|Sferra, Thomas J|Peng, Jun
PMID: 24231788
Journal: Pharmacol Res. 2014 Jan;79:34-74.
Title: The ErbB/HER family of protein-tyrosine kinases and cancer.
Author: Roskoski, Robert Jr
PMID: 24269963
Journal: Hum Mutat. 2014 Feb;35(2):208-14.
Title: Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.
Author: Crowley, Emily Hannah|Arena, Sabrina|Lamba, Simona|Di Nicolantonio, Federica|Bardelli, Alberto
PMID: 24282149
Journal: Oncol Rep. 2014 Feb;31(2):737-44.
Title: Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells.
Author: Chen, Liang|Kang, Qiao-Hui|Chen, Ying|Zhang, Ya-Hong|Li, Qian|Xie, Song-Qiang|Wang, Chao-Jie
PMID: 24297510
Journal: Biochem Biophys Res Commun. 2014 Jan 10;443(2):406-12.
Title: Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014.
Author: Huo, Hai-zhong|Zhou, Zhi-yuan|Wang, Bing|Qin, Jian|Liu, Wen-yong|Gu, Yan
PMID: 24309100
Journal: J Biol Chem. 2014 Jan 24;289(4):1917-29.
Title: Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.
Author: Stachel, Imke|Geismann, Claudia|Aden, Konrad|Deisinger, Florian|Rosenstiel, Philip|Schreiber, Stefan|Sebens, Susanne|Arlt, Alexander|Schafer, Heiner
PMID: 24311782
Journal: Eur J Cancer. 2014 Feb;50(3):663-74.
Title: Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas.
Author: Picault, Francois-Xavier|Chaves-Almagro, Carline|Projetti, Fabrice|Prats, Herve|Masri, Bernard|Audigier, Yves
PMID: 24316062
Journal: Biochim Biophys Acta. 2014 Mar;1840(3):1135-44.
Title: Powerful tumor cell growth-inhibiting activity of a synthetic derivative of atractyligenin: involvement of PI3K/Akt pathway and thioredoxin system.
Author: Cotugno, Roberta|Gallotta, Dario|Piaz, Fabrizio Dal|Apicella, Ivana|De Falco, Sandro|Rosselli, Sergio|Bruno, Maurizio|Belisario, Maria Antonietta
PMID: 24321480
Journal: Cell Death Differ. 2014 Apr;21(4):568-81.
Title: Calcium deficiency-induced and TRP channel-regulated IGF1R-PI3K-Akt signaling regulates abnormal epithelial cell proliferation.
Author: Dai, W|Bai, Y|Hebda, L|Zhong, X|Liu, J|Kao, J|Duan, C
PMID: 24336047
Journal: Oncol Rep. 2014 Feb;31(2):625-33.
Title: (-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer.
Author: Maruyama, Takehito|Murata, Soichiro|Nakayama, Ken|Sano, Naoki|Ogawa, Koichi|Nowatari, Takeshi|Tamura, Takafumi|Nozaki, Reiji|Fukunaga, Kiyoshi|Ohkohchi, Nobuhiro
PMID: 24337301
Journal: Tumour Biol. 2014 Apr;35(4):3525-34.
Title: The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines.
Author: Sahlberg, Sara Haggblad|Gustafsson, Ann-Sofie|Pendekanti, Prathyusha N|Glimelius, Bengt|Stenerlow, Bo
PMID: 24338765
Journal: Biochem Biophys Res Commun. 2014 Jan 17;443(3):852-7.
Title: AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Author: Igarashi, Maki|Hippo, Yoshitaka|Ochiai, Masako|Fukuda, Hirokazu|Nakagama, Hitoshi
PMID: 24342614
Journal: Clin Colorectal Cancer. 2014 Mar;13(1):5-13.
Title: The role of Src in colon cancer and its therapeutic implications.
Author: Chen, Jiezhong|Elfiky, Aymen|Han, Mei|Chen, Chen|Saif, M Wasif
PMID: 24361441
Journal: Br J Cancer. 2014 Feb 18;110(4):946-57.
Title: Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
Author: Zhang, B|Zhang, B|Chen, X|Bae, S|Singh, K|Washington, M K|Datta, P K
PMID: 24384683
Journal: Oncotarget. 2014 Jan 15;5(1):49-66.
Title: mTOR pathway in colorectal cancer: an update.
Author: Francipane, Maria Giovanna|Lagasse, Eric
PMID: 24393708
Journal: Mol Med Rep. 2014 Mar;9(3):935-40.
Title: Isorhamnetin suppresses colon cancer cell growth through the PI3KAktmTOR pathway.
Author: Li, Chuan|Yang, Xi|Chen, Cheng|Cai, Shaoxin|Hu, Junbo
PMID: 24398569
Journal: Eur J Cancer. 2014 Apr;50(6):1207-21.
Title: Clinical and biological significance of miR-378a-3p and miR-378a-5p in colorectal cancer.
Author: Li, Hui|Dai, Sujuan|Zhen, Tiantian|Shi, Huijuan|Zhang, Fenfen|Yang, Yang|Kang, Lili|Liang, Yingjie|Han, Anjia
PMID: 24412052
Journal: Br J Cancer. 2014 Feb 18;110(4):935-45.
Title: Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells.
Author: To, S K Y|Zeng, W-J|Zeng, J-Z|Wong, A S T
PMID: 24423919
Journal: Cancer Biol Ther. 2014;15(2):147-8.
Title: When to screen and not to screen.
Author: Cruickshanks, Nichola
PMID: 24424112
Journal: Int J Oncol. 2014 Mar;44(3):905-11.
Title: MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells.
Author: Lee, Sun Hwa|Kang, Yong Jung|Sung, Bokyung|Kim, Dong Hwan|Lim, Hyun Sook|Kim, Hye Rim|Kim, Seong Jin|Yoon, Jeong-Hyun|Moon, Hyung Ryong|Chung, Hae Young|Kim, Nam Deuk
PMID: 24424889
Journal: Biochem Biophys Res Commun. 2014 Feb 7;444(2):199-204.
Title: MicroRNA-375 inhibits colorectal cancer growth by targeting PIK3CA.
Author: Wang, Yihui|Tang, Qingchao|Li, Mingqi|Jiang, Shixiong|Wang, Xishan
PMID: 24440701
Journal: Int J Clin Oncol. 2014 Apr;19(2):211-9.
Title: Is biomarker research advancing in the era of personalized medicine for head and neck cancer?
Author: Yokota, Tomoya
PMID: 24442754
Journal: Mol Cancer Ther. 2014 Apr;13(4):938-47.
Title: PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential.
Author: Cristobal, Ion|Manso, Rebeca|Rincon, Raul|Carames, Cristina|Senin, Clara|Borrero, Aurea|Martinez-Useros, Javier|Rodriguez, Maria|Zazo, Sandra|Aguilera, Oscar|Madoz-Gurpide, Juan|Rojo, Federico|Garcia-Foncillas, Jesus
PMID: 24448818
Journal: J Biol Chem. 2014 Mar 7;289(10):6513-25.
Title: p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.
Author: Okayama, Sachiyo|Kopelovich, Levy|Balmus, Gabriel|Weiss, Robert S|Herbert, Brittney-Shea|Dannenberg, Andrew J|Subbaramaiah, Kotha
PMID: 24451373
Journal: Mol Biol Rep. 2014;41(4):2101-8.
Title: Matrine inhibits proliferation and induces apoptosis of human colon cancer LoVo cells by inactivating Akt pathway.
Author: Zhang, Shujun|Cheng, Binglin|Li, Hali|Xu, Wei|Zhai, Bo|Pan, Shangha|Wang, Lei|Liu, Ming|Sun, Xueying
PMID: 24452711
Journal: PLoS One. 2014 Jan 15;9(1):e84597.
Title: MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance.
Author: Lee, Chang Gong|McCarthy, Susan|Gruidl, Mike|Timme, Cindy|Yeatman, Timothy J
PMID: 24454732
Journal: Nat Commun. 2014;5:3159.
Title: SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.
Author: Naudin, Cecile|Sirvent, Audrey|Leroy, Cedric|Larive, Romain|Simon, Valerie|Pannequin, Julie|Bourgaux, Jean-Francois|Pierre, Josiane|Robert, Bruno|Hollande, Frederic|Roche, Serge
PMID: 24457997
Journal: Digestion. 2014;89(1):18-23.
Title: Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author: Okada, Yasuyuki|Miyamoto, Hiroshi|Goji, Takahiro|Takayama, Tetsuji
PMID: 24458108
Journal: Biochem Pharmacol. 2014 Mar 15;88(2):150-7.
Title: Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway.
Author: Li, Yuhua|Sun, Yang|Fan, Lei|Zhang, Feng|Meng, Jin|Han, Jin|Guo, Xin|Zhang, Dian|Zhang, Rong|Yue, Zhenggang|Mei, Qibing
PMID: 24462916
Journal: Acta Pharmacol Sin. 2014 Mar;35(3):394-400.
Title: OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
Author: Arafa, El-shaimaa A|Abdelazeem, Ahmed H|Arab, Hany H|Omar, Hany A
PMID: 24464048
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Feb;306(3):G229-43.
Title: Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis.
Author: Josse, Claire|Bouznad, Nassim|Geurts, Pierre|Irrthum, Alexandre|Huynh-Thu, Van Anh|Servais, Laurence|Hego, Alexandre|Delvenne, Philippe|Bours, Vincent|Oury, Cecile
PMID: 24464560
Journal: Fitoterapia. 2014 Apr;94:36-47.
Title: Isoangustone A induces apoptosis in SW480 human colorectal adenocarcinoma cells by disrupting mitochondrial functions.
Author: Huang, Wei|Tang, Shunan|Qiao, Xue|Ma, Wanwan|Ji, Shuai|Wang, Kui|Ye, Min|Yu, Siwang
PMID: 24486984
Journal: Dis Model Mech. 2014 Mar;7(3):387-96.
Title: Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models.
Author: Alamo, Patricia|Gallardo, Alberto|Pavon, Miguel A|Casanova, Isolda|Trias, Manuel|Mangues, Maria A|Vazquez, Esther|Villaverde, Antonio|Mangues, Ramon|Cespedes, Maria V
PMID: 24487410
Journal: Biol Pharm Bull. 2014;37(2):315-21.
Title: Asterosaponins from the Starfish Astropecten monacanthus suppress growth and induce apoptosis in HL-60, PC-3, and SNU-C5 human cancer cell lines.
Author: Thao, Nguyen Phuong|Luyen, Bui Thi Thuy|Kim, Eun-Ji|Kang, Hee-Kyoung|Kim, Sohyun|Cuong, Nguyen Xuan|Nam, Nguyen Hoai|Kiem, Phan Van|Minh, Chau Van|Kim, Young Ho
PMID: 24492728
Journal: J Cancer Res Clin Oncol. 2014 Apr;140(4):561-71.
Title: Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism.
Author: Wang, Hsei-Wei|Yang, Shung-Haur|Huang, Guan-Da|Lin, Jen-Kou|Chen, Wei-Shone|Jiang, Jeng-Kai|Lan, Yuan-Tzu|Lin, Chun-Chi|Hwang, Wei-Lun|Tzeng, Cheng-Hwai|Li, Anna Fen-Yau|Yen, Chueh-Chuan|Teng, Hao-Wei
PMID: 24493623
Journal: Mol Cancer. 2014 Feb 4;13:21.
Title: Dovitinib synergizes with oxaliplatin in suppressing cell proliferation and inducing apoptosis in colorectal cancer cells regardless of RAS-RAF mutation status.
Author: Gaur, Shikha|Chen, Linling|Ann, Vincent|Lin, Wei-Chen|Wang, Yafan|Chang, Vincent H S|Hsu, Nan Yong|Shia, Her-Shuyong|Yen, Yun
PMID: 24495750
Journal: Mol Biol Rep. 2014 May;41(5):3359-67.
Title: PI3K/Akt pathway involving into apoptosis and invasion in human colon cancer cells LoVo.
Author: Jiang, Qun Guang|Li, Tai Yuan|Liu, Dong Ning|Zhang, Hai Tao
PMID: 24496855
Journal: Int J Mol Sci. 2014 Feb 17;15(2):2722-37.
Title: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
Author: Lee, Hyun Sook|Cho, Han Jin|Yu, Rina|Lee, Ki Won|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 24549175
Journal: Apoptosis. 2014 May;19(5):860-70.
Title: Tropomyosin-related kinase B promotes distant metastasis of colorectal cancer through protein kinase B-mediated anoikis suppression and correlates with poor prognosis.
Author: Fan, Meng|Sun, Jianyong|Wang, Wei|Fan, Jing|Wang, Lei|Zhang, Xiang|Yang, Angang|Wang, Weizhong|Zhang, Rui|Li, Jipeng
PMID: 24549576
Journal: Mol Cancer Ther. 2014 May;13(5):1298-308.
Title: Aurora kinase inhibition induces PUMA via NF-kappaB to kill colon cancer cells.
Author: Sun, Jing|Knickelbein, Kyle|He, Kan|Chen, Dongshi|Dudgeon, Crissy|Shu, Yongqian|Yu, Jian|Zhang, Lin
PMID: 24563542
Journal: Oncogenesis. 2014 Feb 24;2:e89.
Title: The essential role of TNIK gene amplification in gastric cancer growth.
Author: Yu, D-H|Zhang, X|Wang, H|Zhang, L|Chen, H|Hu, M|Dong, Z|Zhu, G|Qian, Z|Fan, J|Su, X|Xu, Y|Zheng, L|Dong, H|Yin, X|Ji, Q|Ji, J
PMID: 24566388
Journal: Asian Pac J Cancer Prev. 2014;15(2):551-60.
Title: Signal transducer and activator of transcription 3 - a promising target in colitis-associated cancer.
Author: Pandurangan, Ashok Kumar|Esa, Norhaizan Mohd
PMID: 24568457
Journal: Clin Transl Gastroenterol. 2014 Feb 27;5:e51.
Title: Sphingosine kinase 1 promotes malignant progression in colon cancer and independently predicts survival of patients with colon cancer by competing risk approach in South asian population.
Author: Tan, Sheryl S L|Khin, Lay W|Wong, Lingkai|Yan, Benedict|Ong, Chee W|Datta, Arpita|Salto-Tellez, Manuel|Lam, Yulin|Yap, Celestial T
PMID: 24572701
Journal: Oncol Rep. 2014 Apr;31(4):1811-7.
Title: Adenomatous polyposis coli determines sensitivity to the EGFR tyrosine kinase inhibitor gefitinib in colorectal cancer cells.
Author: Zhang, Yining|Xiao, Qinghuan|Zhang, Huijing|Sun, Xuren|Ge, Huijuan|Liu, Xiaoming|Guan, Lin|Sun, Mingjun
PMID: 24573033
Journal: BMC Cancer. 2014 Mar 1;14:145.
Title: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer.
Author: Agarwal, Ekta|Chaudhuri, Anathbandhu|Leiphrakpam, Premila D|Haferbier, Katie L|Brattain, Michael G|Chowdhury, Sanjib
PMID: 24581231
Journal: PLoS One. 2014 Mar 3;9(3):e90062.
Title: Human phosphatidylethanolamine-binding protein 4 promoted the radioresistance of human rectal cancer by activating Akt in an ROS-dependent way.
Author: Qiu, Jianming|Yang, Guangen|Lin, Ali|Shen, Zhong|Wang, Dong|Ding, Lei
PMID: 24594691
Journal: J Cancer Res Clin Oncol. 2014 May;140(5):737-48.
Title: EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.
Author: Razis, Evangelia|Pentheroudakis, George|Rigakos, George|Bobos, Mattheos|Kouvatseas, George|Tzaida, Olympia|Makatsoris, Thomas|Papakostas, Pavlos|Bai, Maria|Goussia, Anna|Samantas, Epaminontas|Papamichael, Demetrios|Romanidou, Ourania|Efstratiou, Ioannis|T
PMID: 24595598
Journal: Nihon Rinsho. 2014 Jan;72(1):29-34.
Title: [Perspective of personalized (precise) cancer therapy based on predictive biomarkers].
Author: Osera, Shozo|Yoshino, Takayuki
PMID: 24597345
Journal: J Exp Clin Cancer Res. 2014 Mar 5;33:24.
Title: CELLFOOD induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways.
Author: Nuvoli, Barbara|Santoro, Raffaela|Catalani, Simona|Battistelli, Serafina|Benedetti, Serena|Canestrari, Franco|Galati, Rossella
PMID: 24598211
Journal: BMC Cancer. 2014 Mar 6;14:160.
Title: Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells.
Author: Park, Ji-Won|Kim, Seung Cheol|Kim, Won Ki|Hong, Jun Pyu|Kim, Kyung-Hee|Yeo, Hyun Yang|Lee, Jae Yong|Kim, M Sun|Kim, Jong Heon|Yang, Se Young|Kim, Dae Yong|Oh, Jae Hwan|Cho, Jae Youl|Yoo, Byong Chul
PMID: 24602180
Journal: Mol Carcinog. 2014 Nov;53(11):926-37.
Title: PPARdelta deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells.
Author: Jeong, Eunshil|Koo, Jung Eun|Yeon, Sang Hyeon|Kwak, Mi-Kyoung|Hwang, Daniel H|Lee, Joo Young
PMID: 24610641
Journal: J Cancer Res Clin Oncol. 2014 May;140(5):769-81.
Title: Temsirolimus and chloroquine cooperatively exhibit a potent antitumor effect against colorectal cancer cells.
Author: Kaneko, Manabu|Nozawa, Hiroaki|Hiyoshi, Masaya|Tada, Noriko|Murono, Koji|Nirei, Takako|Emoto, Shigenobu|Kishikawa, Junko|Iida, Yuuki|Sunami, Eiji|Tsuno, Nelson H|Kitayama, Joji|Takahashi, Koki|Watanabe, Toshiaki
PMID: 24619662
Journal: Invest New Drugs. 2014 Jun;32(3):424-35.
Title: Radiosensitizing activity of a novel Benzoxazine through the promotion of apoptosis and inhibition of DNA repair.
Author: Radhamani, Suraj|Bradley, Christopher|Meehan-Andrews, Terri|Ihmaid, Saleh K|Al-Rawi, Jasim
PMID: 24627282
Journal: J Pineal Res. 2014 May;56(4):415-26.
Title: Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-kappabeta.
Author: Leon, Josefa|Casado, Jorge|Jimenez Ruiz, Sergio M|Zurita, Maria Sol|Gonzalez-Puga, Cristina|Rejon, Juan D|Gila, Ana|Munoz de Rueda, Paloma|Pavon, Esther J|Reiter, Russel J|Ruiz-Extremera, Angela|Salmeron, Javier
PMID: 24628039
Journal: Mol Cancer. 2014 Mar 14;13:58.
Title: Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer.
Author: Romain, Benoit|Hachet-Haas, Muriel|Rohr, Serge|Brigand, Cecile|Galzi, Jean-Luc|Gaub, Marie-Pierre|Pencreach, Erwan|Guenot, Dominique
PMID: 24629239
Journal: Clin Cancer Res. 2014 May 15;20(10):2793-804.
Title: A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.
Author: Tabernero, Josep|Elez, Maria Elena|Herranz, Maria|Rico, Isabel|Prudkin, Ludmila|Andreu, Jordi|Mateos, Jose|Carreras, Maria Josep|Han, May|Gifford, James|Credi, Marc|Yin, Wei|Agarwal, Shefali|Komarnitsky, Philip|Baselga, Jose
PMID: 24634378
Journal: Mol Cancer Ther. 2014 May;13(5):1345-55.
Title: ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models.
Author: Zhang, Li|Castanaro, Carla|Luan, Bo|Yang, Katie|Fan, Liangfen|Fairhurst, Jeanette L|Rafique, Ashique|Potocky, Terra B|Shan, Jing|Delfino, Frank J|Shi, Ergang|Huang, Tammy|Martin, Joel H|Chen, Gang|Macdonald, Douglas|Rudge, John S|Thurston, Gavin|Daly, Chr
PMID: 24634416
Journal: Mol Cancer Ther. 2014 May;13(5):1130-41.
Title: Protein kinase d as a potential chemotherapeutic target for colorectal cancer.
Author: Wei, Ning|Chu, Edward|Wipf, Peter|Schmitz, John C
PMID: 24634417
Journal: Biomed Rep. 2014 Mar;2(2):250-254.
Title: Aged black garlic extract inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway.
Author: Dong, Menghua|Yang, Guiqing|Liu, Hanchen|Liu, Xiaoxu|Lin, Sixiang|Sun, Dongning|Wang, Yishan
PMID: 24649105
Journal: Cancer Lett. 2014 Jun 28;348(1-2):77-87.
Title: CCL20 and CXCL8 synergize to promote progression and poor survival outcome in patients with colorectal cancer by collaborative induction of the epithelial-mesenchymal transition.
Author: Cheng, Xian-Shuo|Li, Yun-Feng|Tan, Jing|Sun, Bin|Xiao, You-Chuan|Fang, Xing-Bao|Zhang, Xiao-Feng|Li, Qiang|Dong, Jian-Hua|Li, Ming|Qian, Hai-hua|Yin, Zheng-Feng|Yang, Zhi-Bin
PMID: 24657657
Journal: Clin Cancer Res. 2014 May 15;20(10):2631-42.
Title: Regulation of colorectal carcinoma stemness, growth, and metastasis by an miR-200c-Sox2-negative feedback loop mechanism.
Author: Lu, Yan-Xia|Yuan, Li|Xue, Xiao-Lei|Zhou, Min|Liu, Yan|Zhang, Chao|Li, Jing-Ping|Zheng, Lin|Hong, Min|Li, Xue-Nong
PMID: 24658157
Journal: Int J Mol Med. 2014 Jun;33(6):1431-40.
Title: TNF-alpha promotes gallbladder cancer cell growth and invasion through autocrine mechanisms.
Author: Zhu, Guangwei|Du, Qiang|Wang, Xiaoqian|Tang, Nanhong|She, Feifei|Chen, Yanling
PMID: 24676340
Journal: Int J Mol Med. 2014 Jun;33(6):1613-20.
Title: Aloperine induces G2/M phase cell cycle arrest and apoptosis in HCT116 human colon cancer cells.
Author: Zhang, Li|Zheng, Yanxin|Deng, Hongzhu|Liang, Lei|Peng, Juan
PMID: 24682388
Journal: J Clin Endocrinol Metab. 2014 Jul;99(7):E1163-72.
Title: ZIC1 is a putative tumor suppressor in thyroid cancer by modulating major signaling pathways and transcription factor FOXO3a.
Author: Qiang, Wei|Zhao, Yuan|Yang, Qi|Liu, Wei|Guan, Haixia|Lv, Siqing|Ji, Meiju|Shi, Bingyin|Hou, Peng
PMID: 24684457
Journal: FEBS Lett. 2014 May 2;588(9):1773-9.
Title: miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway.
Author: Wei, Zhonghua|Cui, Long|Mei, Zubing|Liu, Min|Zhang, Daoxiang
PMID: 24685694
Journal: Anticancer Res. 2014 Apr;34(4):1793-800.
Title: COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-alpha.
Author: Bocca, Claudia|Bozzo, Francesca|Miglietta, Antonella
PMID: 24692712
Journal: Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title: The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author: Abdul-Jalil, Khairun I|Sheehan, Katherine M|Toomey, Sinead|Schmid, Jasmin|Prehn, Jochen|O'Grady, Anthony|Cummins, Robert|O'Neill, Brian|McNamara, Deborah A|Deasy, Joseph|Breathnach, Oscar|Grogan, Liam|Rogers, Ailin|Doherty, Glen|Winter, Des|Ryan, John|El-
PMID: 24700299
Journal: BMC Cancer. 2014 Apr 4;14:240.
Title: Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions.
Author: Pomerleau, Veronique|Landry, Melissa|Bernier, Jimmy|Vachon, Pierre H|Saucier, Caroline
PMID: 24708867
Journal: Neoplasia. 2014 Feb;16(2):147-57.
Title: BMX acts downstream of PI3K to promote colorectal cancer cell survival and pathway inhibition sensitizes to the BH3 mimetic ABT-737.
Author: Potter, Danielle S|Kelly, Paul|Denneny, Olive|Juvin, Veronique|Stephens, Len R|Dive, Caroline|Morrow, Christopher J
PMID: 24709422
Journal: FEBS Lett. 2014 May 21;588(10):1921-9.
Title: Phosphorylation and changes in the distribution of nucleolin promote tumor metastasis via the PI3K/Akt pathway in colorectal carcinoma.
Author: Wu, Dong-ming|Zhang, Peng|Liu, Ru-yan|Sang, Ya-xiong|Zhou, Cong|Xu, Guang-chao|Yang, Jin-liang|Tong, Ai-ping|Wang, Chun-ting
PMID: 24713430
Journal: Cell Physiol Biochem. 2014;33(4):933-44.
Title: A novel small-molecule YLT205 induces apoptosis in human colorectal cells via mitochondrial apoptosis pathway in vitro and inhibits tumor growth in vivo.
Author: Zhu, Yongxia|Xia, Yong|Ye, Tinghong|Shi, Xuanhong|Song, Xuejiao|Liu, Li|Zeng, Jun|Wang, Ningyu|Luo, Yong|Han, Yuanping|Yu, Luoting
PMID: 24713812
Journal: Curr Cancer Drug Targets. 2014;14(4):323-36.
Title: Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.
Author: Derry, Molly M|Somasagara, Ranganatha R|Raina, Komal|Kumar, Sushil|Gomez, Joe|Patel, Manisha|Agarwal, Rajesh|Agarwal, Chapla
PMID: 24724981
Journal: Chem Biol Interact. 2014 Jun 25;217:1-8.
Title: N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells.
Author: Liu, Ling-Yu|Huang, Wei-Jan|Ho, Feng-Ming|Lin, Ren-Jye|Lin, Shyr-Yi|Suk, Fat-Moon|Liang, Yu-Chih
PMID: 24727557
Journal: PLoS One. 2014 Apr 17;9(4):e95588.
Title: Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability.
Author: Seo, Bo Ram|Min, Kyoung-Jin|Cho, Il Je|Kim, Sang Chan|Kwon, Taeg Kyu
PMID: 24743574
Journal: Tumour Biol. 2014 Jul;35(7):7035-45.
Title: AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells.
Author: Shi, Xiaoming|Wu, Shengchun|Yang, Yongbin|Tang, Lei|Wang, Yuexin|Dong, Junjie|Lu, Bonan|Jiang, Guangwei|Zhao, Wei
PMID: 24752576
Journal: Int J Oncol. 2014 Jul;45(1):104-12.
Title: The PTEN/PI3K/Akt and Wnt/beta-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation.
Author: Liu, Ying-Zi|Wu, Ke|Huang, Jun|Liu, Yang|Wang, Xin|Meng, Zi-Jun|Yuan, Shuang-Xue|Wang, Dong-Xu|Luo, Jin-Yong|Zuo, Guo-Wei|Yin, Liang-Jun|Chen, Liang|Deng, Zhong-Liang|Yang, Jun-Qin|Sun, Wen-Juan|He, Bai-Cheng
PMID: 24756222
Journal: PLoS One. 2014 Apr 23;9(4):e94621.
Title: Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
Author: Sahlberg, Sara Haggblad|Spiegelberg, Diana|Glimelius, Bengt|Stenerlow, Bo|Nestor, Marika
PMID: 24760019
Journal: Biochim Biophys Acta. 2014 Aug;1840(8):2651-61.
Title: EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.
Author: Ellina, Maria-Ioanna|Bouris, Panagiotis|Aletras, Alexios J|Theocharis, Achilleas D|Kletsas, Dimitris|Karamanos, Nikos K
PMID: 24792576
Journal: PLoS One. 2014 May 8;9(5):e96418.
Title: ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid.
Author: Zhang, Haiyuan|Lei, Yunlong|Yuan, Ping|Li, Lingjun|Luo, Chao|Gao, Rui|Tian, Jun|Feng, Zuohua|Nice, Edouard C|Sun, Jun
PMID: 24810758
Journal: Oncotarget. 2014 Apr 30;5(8):2149-60.
Title: The EF-hand calcium-binding protein tescalcin is a potential oncotarget in colorectal cancer.
Author: Kang, Yun Hee|Han, Seung Ro|Kim, Jong-Tae|Lee, Seon-Jin|Yeom, Young Il|Min, Jeong-Ki|Lee, Chul-Ho|Kim, Jae Wha|Yoon, Suk Ran|Yoon, Do-Young|Hong, Kwan Soo|Hwang, Geum-Sook|Kim, Hee Cheol|Lee, Young-Ha|Lee, Hee Gu
PMID: 24811141
Journal: Clin Cancer Res. 2014 Jul 15;20(14):3775-86.
Title: Primary and acquired resistance of colorectal cancer cells to anti-EGFR antibodies converge on MEK/ERK pathway activation and can be overcome by combined MEK/EGFR inhibition.
Author: Troiani, Teresa|Napolitano, Stefania|Vitagliano, Donata|Morgillo, Floriana|Capasso, Anna|Sforza, Vincenzo|Nappi, Anna|Ciardiello, Davide|Ciardiello, Fortunato|Martinelli, Erika
PMID: 24812410
Journal: Asian Pac J Cancer Prev. 2014;15(7):3145-9.
Title: Pathway and network analysis in glioma with the partial least squares method.
Author: Gu, Wen-Tao|Gu, Shi-Xin|Shou, Jia-Jun
PMID: 24815461
Journal: Int J Oncol. 2014 Aug;45(2):611-8.
Title: Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway.
Author: Li, Xin-Xiang|Huang, Li-Yong|Peng, Jun-Jie|Liang, Lei|Shi, De-Bing|Zheng, Hong-Tu|Cai, San-Jun
PMID: 24818842
Journal: Carcinogenesis. 2014 Oct;35(10):2175-82.
Title: MicroRNA-21 promotes tumour malignancy via increased nuclear translocation of beta-catenin and predicts poor outcome in APC-mutated but not in APC-wild-type colorectal cancer.
Author: Lin, Po-Lin|Wu, De-Wei|Huang, Chi-Chou|He, Tsung-Ying|Chou, Ming-Chih|Sheu, Gwo-Tarng|Lee, Huei
PMID: 24832083
Journal: Tumour Biol. 2014 Aug;35(8):8161-7.
Title: LMO1 is a novel oncogene in colorectal cancer and its overexpression is a new predictive marker for anti-EGFR therapy.
Author: Liu, Junguang|Yan, Peiyun|Jing, Niancai|Yang, Jili
PMID: 24845030
Journal: Tumour Biol. 2014 Sep;35(9):8639-43.
Title: Nrdp1 inhibits growth of colorectal cancer cells by nuclear retention of p27.
Author: Lu, Hang|Li, Hua|Mao, Dong|Zhu, Zhitu|Sun, Hongzhi
PMID: 24867101
Journal: PLoS One. 2014 May 29;9(5):e97719.
Title: Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.
Author: Lou, Yun-feng|Zou, Zheng-zhi|Chen, Pin-jia|Huang, Guo-bin|Li, Bin|Zheng, De-qing|Yu, Xiu-rong|Luo, Xiao-yong
PMID: 24874286
Journal: Ann Surg Oncol. 2014 Dec;21 Suppl 4:S703-10.
Title: LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer.
Author: He, Tsung-Ying|Tsai, Lung-Hung|Huang, Chi-Chou|Chou, Ming-Chih|Lee, Huei
PMID: 24879590
Journal: Br J Cancer. 2014 Jul 8;111(1):101-11.
Title: BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt.
Author: Pal, I|Sarkar, S|Rajput, S|Dey, K K|Chakraborty, S|Dash, R|Das, S K|Sarkar, D|Barile, E|De, S K|Pellecchia, M|Fisher, P B|Mandal, M
PMID: 24892445
Journal: PLoS One. 2014 Jun 6;9(6):e98858.
Title: Dormancy of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia.
Author: Endo, Hiroko|Okuyama, Hiroaki|Ohue, Masayuki|Inoue, Masahiro
PMID: 24905002
Journal: Mol Oncol. 2014 Sep 12;8(6):1084-94.
Title: Acquired resistance to EGFR-targeted therapies in colorectal cancer.
Author: Van Emburgh, Beth O|Sartore-Bianchi, Andrea|Di Nicolantonio, Federica|Siena, Salvatore|Bardelli, Alberto
PMID: 24913799
Journal: Anticancer Res. 2014 Jun;34(6):2967-71.
Title: The steroidal Na+/K+ ATPase inhibitor 3-[(R)-3-pyrrolidinyl]oxime derivative (3-R-POD) induces potent pro-apoptotic responses in colonic tumor cells.
Author: Alkahtani, Saad Hussin
PMID: 24922661
Journal: Oncotarget. 2014 May 30;5(10):2999-3011.
Title: WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear beta-Catenin depend on active PI3K signaling.
Author: Ormanns, Steffen|Neumann, Jens|Horst, David|Kirchner, Thomas|Jung, Andreas
PMID: 24930890
Journal: Oncol Lett. 2014 Jun;7(6):1761-1766.
Title: 'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patients.
Author: Fang, Weijia|Radovich, Milan|Zheng, Yulong|Fu, Cai-Yun|Zhao, Peng|Mao, Chengyu|Zheng, Yi|Zheng, Shusen
PMID: 24932229
Journal: Oncol Lett. 2014 Jun;7(6):2047-2052.
Title: Inhibition of ovarian cancer cell proliferation by Pien Tze Huang via the AKT-mTOR pathway.
Author: He, Fan|Wu, Hui-Ni|Cai, Mu-Yan|Li, Chang-Peng|Zhang, Xin|Wan, Quan|Tang, Shuang-Bo|Cheng, Jian-Ding
PMID: 24932287
Journal: Int J Med Sci. 2014 Jun 8;11(8):841-9.
Title: Activation of the PI3K/Akt/mTOR/p70S6K pathway is involved in S100A4-induced viability and migration in colorectal cancer cells.
Author: Wang, Haiyan|Duan, Liang|Zou, Zhengyu|Li, Huan|Yuan, Shimei|Chen, Xian|Zhang, Yunyuan|Li, Xueru|Sun, Hui|Zha, He|Zhang, Yan|Zhou, Lan
PMID: 24936148
Journal: PLoS One. 2014 Jun 18;9(6):e99590.
Title: Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy.
Author: Algars, Annika|Avoranta, Tuulia|Osterlund, Pia|Lintunen, Minnamaija|Sundstrom, Jari|Jokilehto, Terhi|Ristimaki, Ari|Ristamaki, Raija|Carpen, Olli
PMID: 24940619
Journal: Biochim Biophys Acta. 2014 Sep;1843(9):2129-37.
Title: Radiation sensitization of tumor cells induced by shear stress: the roles of integrins and FAK.
Author: Luo, Chi-Wen|Wu, Chia-Ching|Ch'ang, Hui-Ju
PMID: 24946134
Journal: Oncotarget. 2014 Jun 15;5(11):3590-606.
Title: HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.
Author: Ramirez, Alberto|Boulaiz, Houria|Morata-Tarifa, Cynthia|Peran, Macarena|Jimenez, Gema|Picon-Ruiz, Manuel|Agil, Ahmad|Cruz-Lopez, Olga|Conejo-Garcia, Ana|Campos, Joaquin M|Sanchez, Ana|Garcia, Maria A|Marchal, Juan A
PMID: 24946763
Journal: Cancer. 2014 Nov 15;120(22):3446-56.
Title: The MAPK pathway across different malignancies: a new perspective.
Author: Burotto, Mauricio|Chiou, Victoria L|Lee, Jung-Min|Kohn, Elise C
PMID: 24948110
Journal: Food Funct. 2014 Aug;5(8):1909-14.
Title: Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation.
Author: Sun, Lijuan|Luo, Cheng|Liu, Jiankang
PMID: 24953710
Journal: Autophagy. 2014 Sep;10(9):1495-508.
Title: Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells.
Author: Xie, Chuan-Ming|Liu, Xiao-Yu|Sham, Kathy W Y|Lai, Josie M Y|Cheng, Christopher H K
PMID: 24955726
Journal: Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.
Title: Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.
Author: Slattery, Martha L|Lundgreen, Abbie|Mullany, Lila E|Penney, Rosalind B|Wolff, Roger K
PMID: 24959314
Journal: PLoS One. 2014 Jun 24;9(6):e99631.
Title: Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
Author: Chiang, En-Pei Isabel|Tsai, Shu-Yao|Kuo, Yueh-Hsiung|Pai, Man-Hui|Chiu, Hsi-Lin|Rodriguez, Raymond L|Tang, Feng-Yao
PMID: 24960186
Journal: PLoS One. 2014 Jun 26;9(6):e98515.
Title: FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Author: Mathur, Anjili|Ware, Christopher|Davis, Lenora|Gazdar, Adi|Pan, Bo-Sheng|Lutterbach, Bart
PMID: 24968263
Journal: Int J Oncol. 2014 Sep;45(3):995-1010.
Title: Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-kappaB in vitro and in vivo.
Author: Tang, Weiwei|Su, Guangjian|Li, Jieyu|Liao, Jinrong|Chen, Shuping|Huang, Chuanzhong|Liu, Fang|Chen, Qiang|Ye, Yunbin
PMID: 24968890
Journal: Int J Oncol. 2014 Sep;45(3):1036-42.
Title: Phloroglucinol induces apoptosis through the regulation of insulin-like growth factor 1 receptor signaling pathways in human colon cancer HT-29 cells.
Author: Kang, Mi-Hye|Kim, In-Hye|Nam, Taek-Jeong
PMID: 24970012
Journal: Oncotarget. 2014 Jul 15;5(13):5138-52.
Title: ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
Author: Lee, Hyunji|Lee, Hyunjung|Chin, Hyunjung|Kim, Kyoungmi|Lee, Daekee
PMID: 24970817
Journal: PLoS One. 2014 Jun 30;9(6):e101137.
Title: CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
Author: Liu, Jinlin|Ke, Fang|Xu, Zhenyao|Liu, Zhaoyuan|Zhang, Lingyun|Yan, Sha|Wang, Zhe|Wang, Hong|Wang, Honglin
PMID: 24979261
Journal: Mol Nutr Food Res. 2014 Sep;58(9):1820-9.
Title: Garcinol suppresses inflammation-associated colon carcinogenesis in mice.
Author: Tsai, Mei-Ling|Chiou, Yi-Shiou|Chiou, Li-Yu|Ho, Chi-Tang|Pan, Min-Hsiung
PMID: 24981158
Journal: Biomed Pharmacother. 2014 Jun;68(5):527-35.
Title: NF-kappaB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Author: Li, Meng|Wang, Xiu'e|Liu, Ming|Qi, Xin|Li, Jing
PMID: 24986326
Journal: Biochim Biophys Acta. 2014 Sep;1842(9):1823-9.
Title: Hyperphosphorylation of PP2A in colorectal cancer and the potential therapeutic value showed by its forskolin-induced dephosphorylation and activation.
Author: Cristobal, Ion|Rincon, Raul|Manso, Rebeca|Madoz-Gurpide, Juan|Carames, Cristina|del Puerto-Nevado, Laura|Rojo, Federico|Garcia-Foncillas, Jesus
PMID: 24997451
Journal: Oncol Lett. 2014 Aug;8(2):493-501.
Title: Progress of cancer research on astrocyte elevated gene-1/Metadherin (Review).
Author: Huang, Yong|Li, LE-Ping
PMID: 25009642
Journal: Amino Acids. 2014 Oct;46(10):2393-401.
Title: Kynurenic acid inhibits colon cancer proliferation in vitro: effects on signaling pathways.
Author: Walczak, Katarzyna|Turski, Waldemar A|Rajtar, Grazyna
PMID: 25012123
Journal: Int J Oncol. 2014 Oct;45(4):1583-93.
Title: Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity.
Author: Nakata, Susumu|Tanaka, Harunari|Ito, Yuichi|Hara, Masayasu|Fujita, Mitsugu|Kondo, Eisaku|Kanemitsu, Yukihide|Yatabe, Yasushi|Nakanishi, Hayao
PMID: 25017791
Journal: Med Oncol. 2014 Aug;31(8):92.
Title: The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer.
Author: Wen, Xiaoxia|Zhu, Jianjun|Dong, Lei|Chen, Yao
PMID: 25023051
Journal: Ann Surg Oncol. 2014 Dec;21(13):4164-73.
Title: SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features.
Author: Li, Tingting|Liao, Xiaoyun|Lochhead, Paul|Morikawa, Teppei|Yamauchi, Mai|Nishihara, Reiko|Inamura, Kentaro|Kim, Sun A|Mima, Kosuke|Sukawa, Yasutaka|Kuchiba, Aya|Imamura, Yu|Baba, Yoshifumi|Shima, Kaori|Meyerhardt, Jeffrey A|Chan, Andrew T|Fuchs, Charles S
PMID: 25023548
Journal: Int J Clin Exp Pathol. 2014 May 15;7(6):3312-7. eCollection 2014.
Title: Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas.
Author: Sangawa, Akiko|Shintani, Michiko|Yamao, Naoki|Kamoshida, Shingo
PMID: 25031754
Journal: J Surg Oncol. 2014 Dec;110(7):828-38.
Title: Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.
Author: Neal, Christopher P|Fry, Andrew M|Moreman, Catherine|McGregor, Angus|Garcea, Giuseppe|Berry, David P|Manson, Margaret M
PMID: 25043295
Journal: Biochem Cell Biol. 2014 Aug;92(4):305-15.
Title: Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells.
Author: Calvo, Natalia|Martin, Maria Julia|de Boland, Ana Russo|Gentili, Claudia
PMID: 25051885
Journal: J Cell Biochem. 2014 Dec;115(12):2133-45.
Title: Molecular mechanisms associated with PTHrP-induced proliferation of colon cancer cells.
Author: Martin, Maria Julia|Calvo, Natalia|de Boland, Ana Russo|Gentili, Claudia
PMID: 25053227
Journal: PLoS One. 2014 Jul 24;9(7):e103298.
Title: Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Author: Ye, Qiurong|Zheng, Ying|Fan, Songqing|Qin, Zailong|Li, Nan|Tang, Anliu|Ai, Feiyan|Zhang, Xuemei|Bian, Yanhui|Dang, Wei|Huang, Jing|Zhou, Ming|Zhou, Yanhong|Xiong, Wei|Yan, Qun|Ma, Jian|Li, Guiyuan
PMID: 25057912
Journal: J Nat Prod. 2014 Aug 22;77(8):1825-30.
Title: 6-Acetonyldihydrochelerythrine Is a Potent Inducer of Apoptosis in HCT116 and SW620 Colon Cancer Cells.
Author: Mansoor, Tayyab A|Borralho, Pedro M|Luo, Xuan|Mulhovo, Silva|Rodrigues, Cecilia M P|Ferreira, Maria-Jose U
PMID: 25066282
Journal: Cancer Lett. 2014 Oct 10;353(1):87-94.
Title: FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways.
Author: Cui, Yan-Mei|Jiang, Dan|Zhang, Shi-Hong|Wu, Ping|Ye, Ya-Ping|Chen, Cui-Min|Tang, Na|Liang, Li|Li, Ting-Ting|Qi, Lu|Wang, Shu-Yang|Jiao, Hong-Li|Lin, Jie|Ding, Yan-Qing|Liao, Wen-Ting
PMID: 25069037
Journal: BMC Complement Altern Med. 2014 Jul 30;14:275.
Title: Essential oil of Pinus koraiensis inhibits cell proliferation and migration via inhibition of p21-activated kinase 1 pathway in HCT116 colorectal cancer cells.
Author: Cho, Sun-Mi|Lee, Eun-Ok|Kim, Sung-Hoon|Lee, Hyo-Jeong
PMID: 25074784
Journal: Int J Nanomedicine. 2014 Jul 16;9:3403-11.
Title: Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways.
Author: Chen, Jiezhong|Shao, Renfu|Li, Li|Xu, Zhi Ping|Gu, Wenyi
PMID: 25075187
Journal: PLoS One. 2014 Aug 4;9(8):e103551.
Title: Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
Author: Lee, Jeeyun|Jain, Anjali|Kim, Phillip|Lee, Tani|Kuller, Anne|Princen, Fred|In-GuDo|Kim, Suk Hyeong|Park, Joon Oh|Park, Young Suk|Singh, Sharat|Kim, Hee Cheol
PMID: 25090459
Journal: Br J Pharmacol. 2014 Dec;171(24):5728-42.
Title: PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling.
Author: Huang, S W|Lien, J C|Kuo, S C|Huang, T F
PMID: 25091695
Journal: J Zhejiang Univ Sci B. 2014 Aug;15(8):701-12.
Title: Sunitinib mesylate inhibits proliferation of human colonic stromal fibroblasts in vitro and in vivo.
Author: Wang, Zhan-huai|Li, Qiong|Ruan, Shu-qin|Xiao, Qian|Liu, Yue|Hu, Ye-ting|Hu, Li-feng|Chen, Hai-yan|Zheng, Shu|Zhang, Su-zhan|Ding, Ke-feng
PMID: 25091988
Journal: Biomed Pharmacother. 2014 Jul;68(6):721-7.
Title: The PI3K/Akt pathway in colitis associated colon cancer and its chemoprevention with celecoxib, a Cox-2 selective inhibitor.
Author: Setia, Shruti|Nehru, Bimla|Sanyal, Sankar Nath
PMID: 25107843
Journal: Toxicol Appl Pharmacol. 2014 Dec 1;281(2):166-73.
Title: Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways.
Author: Tong, Qingyi|Qing, Yong|Wu, Yang|Hu, Xiaojuan|Jiang, Lei|Wu, Xiaohua
PMID: 25111127
Journal: PLoS One. 2014 Aug 14;9(8):e104891.
Title: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Author: Lien, Gi-Shih|Wu, Ming-Shun|Bien, Mauo-Ying|Chen, Chien-Hsin|Lin, Chien-Huang|Chen, Bing-Chang
PMID: 25122478
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G749-59.
Title: PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors.
Author: Liu, Chunsheng|Li, Jiachu|Xiang, Xiaoyu|Guo, Luyang|Tu, Kangsheng|Liu, Qinghua|Shah, Vijay H|Kang, Ningling
PMID: 25169976
Journal: Mol Cancer. 2014 Aug 29;13:201.
Title: Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.
Author: El-Baba, Chirine|Mahadevan, Vijayalakshmi|Fahlbusch, Fabian B|Mohan S, Suma|Rau, Tilman T|Gali-Muhtasib, Hala|Schneider-Stock, Regine
PMID: 25174975
Journal: Cancer Prev Res (Phila). 2014 Nov;7(11):1138-48.
Title: Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer.
Author: Vasudevan, Anita|Yu, Yingjie|Banerjee, Sanjeev|Woods, James|Farhana, Lulu|Rajendra, Sindhu G|Patel, Aamil|Dyson, Gregory|Levi, Edi|Maddipati, Krishna Rao|Majumdar, Adhip P N|Nangia-Makker, Pratima
PMID: 25193342
Journal: Ann Oncol. 2014 Nov;25(11):2196-204.
Title: MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of beta-catenin signaling.
Author: Zhang, J X|Mai, S J|Huang, X X|Wang, F W|Liao, Y J|Lin, M C|Kung, H F|Zeng, Y X|Xie, D
PMID: 25193986
Journal: J Transl Med. 2014 Sep 8;12:244.
Title: Tumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway.
Author: Xu, Lijun|Zhang, Yue|Wang, Hui|Zhang, Guanhua|Ding, Yanqing|Zhao, Liang
PMID: 25196260
Journal: Cancer Lett. 2014 Nov 28;354(2):355-64.
Title: Synergism of PI3K/Akt inhibition and Fas activation on colon cancer cell death.
Author: Zhu, Liang|Derijard, Benoit|Chakrabandhu, Krittalak|Wang, Bing-Shun|Chen, Hong-Zhuan|Hueber, Anne-Odile
PMID: 25199763
Journal: Mol Nutr Food Res. 2014 Dec;58(12):2274-85.
Title: Carnosic acid suppresses colon tumor formation in association with antiadipogenic activity.
Author: Kim, Yun-Ji|Kim, Jong-Sang|Seo, Young Rok|Park, Jung Han Yoon|Choi, Myung-Sook|Sung, Mi-Kyung
PMID: 25204550
Journal: Biochem Biophys Res Commun. 2014 Sep 26;452(3):858-64.
Title: Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway.
Author: Piao, Zhengri|Hong, Chang-Soo|Jung, Mi-Ran|Choi, Chan|Park, Young-Kyu
PMID: 25218472
Journal: Cancer Lett. 2014 Dec 1;355(1):141-7.
Title: Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
Author: Saxena, Ashish|Shoeb, Mohammad|Tammali, Ravinder|Ramana, Kota V|Srivastava, Satish K
PMID: 25218594
Journal: Asian Pac J Cancer Prev. 2014;15(17):7245-9.
Title: GRP78 secreted by colon cancer cells facilitates cell proliferation via PI3K/Akt signaling.
Author: Fu, Rong|Yang, Peng|Wu, Hai-Li|Li, Zong-Wei|Li, Zhuo-Yu
PMID: 25227822
Journal: Exp Mol Pathol. 2014 Dec;97(3):321-31.
Title: Heme oxygenase-1 has antitumoral effects in colorectal cancer: involvement of p53.
Author: Andres, Nancy Carolina|Fermento, Maria Eugenia|Gandini, Norberto Ariel|Romero, Alejandro Lopez|Ferro, Alejandro|Donna, Lucila Gonzalez|Curino, Alejandro Carlos|Facchinetti, Maria Marta
PMID: 25236576
Journal: Anticancer Res. 2014 Oct;34(10):5465-72.
Title: Lysophosphatidylserine stimulates chemotactic migration of colorectal cancer cells through GPR34 and PI3K/Akt pathway.
Author: Iida, Yuuki|H Tsuno, Nelson|Kishikawa, Junko|Kaneko, Kensuke|Murono, Koji|Kawai, Kazushige|Ikeda, Toshiyuki|Ishihara, Soichiro|Yamaguchi, Hironori|Sunami, Eiji|Kitayama, Joji|Yatomi, Yutaka|Watanabe, Toshiaki
PMID: 25275042
Journal: Oncotarget. 2014 Sep 15;5(17):7936-44.
Title: Mutant NRASQ61 shares signaling similarities across various cancer types--potential implications for future therapies.
Author: Vujic, Igor|Posch, Christian|Sanlorenzo, Martina|Yen, Adam J|Tsumura, Aaron|Kwong, Andrew|Feichtenschlager, Valentin|Lai, Kevin|Arneson, Douglas V|Rappersberger, Klemens|Ortiz-Urda, Susana M
PMID: 25277205
Journal: Nutrition. 2014 Nov-Dec;30(11-12):1242-56.
Title: Colon carcinogenesis: influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds.
Author: Kasdagly, Maria|Radhakrishnan, Sridhar|Reddivari, Lavanya|Veeramachaneni, D N Rao|Vanamala, Jairam
PMID: 25280404
Journal: Br J Cancer. 2014 Nov 11;111(10):1932-44.
Title: A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.
Author: Brana, I|Berger, R|Golan, T|Haluska, P|Edenfield, J|Fiorica, J|Stephenson, J|Martin, L P|Westin, S|Hanjani, P|Jones, M B|Almhanna, K|Wenham, R M|Sullivan, D M|Dalton, W S|Gunchenko, A|Cheng, J D|Siu, L L|Gray, J E
PMID: 25290091
Journal: Oncotarget. 2014 Oct 30;5(20):9980-91.
Title: HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.
Author: Nagaraju, Ganji Purnachandra|Alese, Olatunji B|Landry, Jerome|Diaz, Roberto|El-Rayes, Bassel F
PMID: 25296971
Journal: Cell Physiol Biochem. 2014;34(4):1402-12.
Title: Membrane androgen receptor down-regulates c-src-activity and beta-catenin transcription and triggers GSK-3beta-phosphorylation in colon tumor cells.
Author: Gu, Shuchen|Honisch, Sabina|Kounenidakis, Michalis|Alkahtani, Saad|Alarifi, Saud|Alevizopoulos, Konstantinos|Stournaras, Christos|Lang, Florian
PMID: 25301365
Journal: Nat Commun. 2014 Oct 13;5:5191.
Title: Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Author: Schulz, Eduard|Klampfl, Petra|Holzapfel, Stefanie|Janecke, Andreas R|Ulz, Peter|Renner, Wilfried|Kashofer, Karl|Nojima, Satoshi|Leitner, Anita|Zebisch, Armin|Wolfler, Albert|Hofer, Sybille|Gerger, Armin|Lax, Sigurd|Beham-Schmid, Christine|Steinke, Verena|
PMID: 25307848
Journal: Biomed Res Int. 2014;2014:568693.
Title: Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
Author: Lange, Falko|Franz, Benjamin|Maletzki, Claudia|Linnebacher, Michael|Huhns, Maja|Jaster, Robert
PMID: 25309914
Journal: Cancer Treat Rev. 2014 Dec;40(10):1182-91.
Title: Improving chemoradiation efficacy by PI3-K/AKT inhibition.
Author: Stegeman, Hanneke|Span, Paul N|Kaanders, Johannes H A M|Bussink, Johan
PMID: 25312653
Journal: Curr Mol Med. 2014;14(9):1126-38.
Title: Cholinergic receptors as target for cancer therapy in a systems medicine perspective.
Author: Russo, P|Del Bufalo, A|Milic, M|Salinaro, G|Fini, M|Cesario, A
PMID: 25324001
Journal: J Cancer Prev. 2014 Sep;19(3):161-9.
Title: Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells.
Author: Lee, Hyun Sook|Cho, Han Jin|Kwon, Gyoo Taik|Park, Jung Han Yoon
PMID: 25337585
Journal: Oncotarget. 2014 Dec 15;5(23):12304-16.
Title: Targeting cytosolic phospholipase A2 alpha in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.
Author: Zheng, Zhong|He, Xiangyi|Xie, Chanlu|Hua, Sheng|Li, Jianfang|Wang, Tingfeng|Yao, Mu|Vignarajan, Soma|Teng, Ying|Hejazi, Leila|Liu, Bingya|Dong, Qihan
PMID: 25365190
Journal: Biosci Rep. 2014 Dec 12;34(6):e00161.
Title: Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells.
Author: Yu, Xiaojun|Zheng, Bo'an|Chai, Rui
PMID: 25370813
Journal: Asian Pac J Cancer Prev. 2014;15(20):8651-6.
Title: Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer.
Author: Zhang, Ji-Hong|Wang, Li-Hua|Li, Xiang-Jun|Wang, Ai-Ping|Reng, Li-Qun|Xia, Feng-Guo|Yang, Zhi-Ping|Jiang, Jing|Wang, Xiao-Dan|Wen, Chun-Yang
PMID: 25374184
Journal: Neoplasia. 2014 Oct 23;16(10):845-60.
Title: Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.
Author: Grasso, Silvina|Tristante, Elena|Saceda, Miguel|Carbonell, Pablo|Mayor-Lopez, Leticia|Carballo-Santana, Mar|Carrasco-Garcia, Estefania|Rocamora-Reverte, Lourdes|Garcia-Morales, Pilar|Carballo, Fernando|Ferragut, Jose A|Martinez-Lacaci, Isabel
PMID: 25379021
Journal: Sci Signal. 2014 Nov 11;7(351):ra107.
Title: Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Author: Belmont, Peter J|Jiang, Ping|McKee, Trevor D|Xie, Tao|Isaacson, Jason|Baryla, Nicole E|Roper, Jatin|Sinnamon, Mark J|Lee, Nathan V|Kan, Julie L C|Guicherit, Oivin|Wouters, Bradly G|O'Brien, Catherine A|Shields, David|Olson, Peter|VanArsdale, Todd|Weinrich
PMID: 25389372
Journal: PLoS One. 2014 Nov 12;9(11):e111814.
Title: Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors.
Author: Cheng, Tzu-Chun|Lai, Ching-Shu|Chung, Min-Ching|Kalyanam, Nagabhushanam|Majeed, Muhammed|Ho, Chi-Tang|Ho, Yuan-Soon|Pan, Min-Hsiung
PMID: 25389774
Journal: PLoS One. 2014 Nov 17;9(11):e113037.
Title: Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Author: Pitts, Todd M|Newton, Timothy P|Bradshaw-Pierce, Erica L|Addison, Rebecca|Arcaroli, John J|Klauck, Peter J|Bagby, Stacey M|Hyatt, Stephanie L|Purkey, Alicia|Tentler, John J|Tan, Aik Choon|Messersmith, Wells A|Eckhardt, S Gail|Leong, Stephen
PMID: 25401499
Journal: BMC Cancer. 2014 Nov 20;14:851.
Title: High mobility group A1 protein expression reduces the sensitivity of colon and thyroid cancer cells to antineoplastic drugs.
Author: D'Angelo, Daniela|Mussnich, Paula|Rosa, Roberta|Bianco, Roberto|Tortora, Giampaolo|Fusco, Alfredo
PMID: 25409711
Journal: Int Surg. 2014 Nov-Dec;99(6):795-801.
Title: Conversion Therapy Using mFOLFOX6 With Panitumumab for Unresectable Liver Metastases From Multiple Colorectal Cancers With Familial Adenomatous Polyposis.
Author: Toiyama, Yuji|Inoue, Yasuhiro|Kitajima, Takahito|Okigami, Masato|Kawamura, Mikio|Kawamoto, Aya|Okugawa, Yoshinaga|Hiro, Jyunichiro|Tanaka, Koji|Mohri, Yasuhiko|Kusunoki, Masato
PMID: 25437589
Journal: Biomed Pharmacother. 2014 Oct;68(8):1023-9.
Title: Upregulation of MAPK/Erk and PI3K/Akt pathways in ulcerative colitis-associated colon cancer.
Author: Setia, Shruti|Nehru, Bimla|Sanyal, Sankar Nath
PMID: 25443414
Journal: Biomed Pharmacother. 2014 Oct;68(8):1089-97.
Title: Down-regulation of sphingosine kinase 2 (SphK2) increases the effects of all-trans-retinoic acid (ATRA) on colon cancer cells.
Author: Chu, Jia-Hui|Gao, Zu-Hua|Qu, Xian-Jun
PMID: 25455157
Journal: Oncotarget. 2014 Dec 15;5(23):11847-56.
Title: The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells.
Author: Kawakami, Hisato|Okamoto, Isamu|Yonesaka, Kimio|Okamoto, Kunio|Shibata, Kiyoko|Shinkai, Yume|Sakamoto, Haruka|Kitano, Michiko|Tamura, Takao|Nishio, Kazuto|Nakagawa, Kazuhiko
PMID: 25474137
Journal: Cancer Biol Ther. 2014;15(12):1646-57.
Title: Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author: Booth, Laurence|Cruickshanks, Nichola|Tavallai, Seyedmehrad|Roberts, Jane L|Peery, Matthew|Poklepovic, Andrew|Dent, Paul
PMID: 25482938
Journal: PLoS One. 2014 Dec 11;9(12):e115068.
Title: Comprehensive suppression of all apoptosis-induced proliferation pathways as a proposed approach to colorectal cancer prevention and therapy.
Author: Bordonaro, Michael|Drago, Eric|Atamna, Wafa|Lazarova, Darina L
PMID: 25500581
Journal: Cell Death Dis. 2014 Dec 11;5:e1570.
Title: XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis.
Author: Ehrenschwender, M|Bittner, S|Seibold, K|Wajant, H
PMID: 25501831
Journal: PLoS One. 2014 Dec 26;9(12):e115980.
Title: MicroRNA-302a functions as a putative tumor suppressor in colon cancer by targeting Akt.
Author: Sun, Shengjie|Zhang, Guoqing|Wu, Zhiyong|Shi, Weiwei|Yang, Bo|Li, Ying
PMID: 25542007
Journal: Cancer Cell Microenviron. 2014;1(5).
Title: New insights into 4E-BP1-regulated translation in cancer progression and metastasis.
Author: Wang, Jun|Ye, Qing|She, Qing-Bai
PMID: 26005705
Journal: Free Radic Biol Med. 2014 Oct;75 Suppl 1:S13.
Title: Akt mediated ROS-dependent selective targeting of mutant KRAS tumors.
Author: Iskandar, Kartini|Rezlan, Majidah|Pervaiz, Shazib
PMID: 26461287
Journal: Acta Pharm Sin B. 2014 Apr;4(2):128-34.
Title: RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells.
Author: Zhang, Hao|Zhang, Shenghua|He, Hongwei|Zhang, Caixia|Chen, Yi|Yu, Dongke|Chen, Jianhua|Shao, Rongguang
PMID: 26579374
Journal: Curr Clin Pharmacol. 2015;10(1):73-81.
Title: K-Ras, intestinal homeostasis and colon cancer.
Author: Goel, Sanjay|Huang, Jie|Klampfer, Lidija
PMID: 24219000
Journal: Biotechnol Appl Biochem. 2015 May-Jun;62(3):401-6.
Title: Periostin induces chemoresistance in colon cancer cells through activation of the PI3K/Akt/survivin pathway.
Author: Xiao, Zhi-ming|Wang, Xiao-yan|Wang, Ai-min
PMID: 24372557
Journal: Environ Toxicol. 2015 Jul;30(7):852-63.
Title: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling.
Author: Ma, Yi-Shih|Hsiao, Yu-Ping|Lin, Ju-Hwa|Hsu, Shu-Chun|Chueh, Fu-Shin|Weng, Shu-Wen|Lai, Kuang-Chi|Lin, Jaung-Geng|Chung, Jing-Gung
PMID: 24497447
Journal: Oncogene. 2015 Feb 26;34(9):1150-9.
Title: Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.
Author: Bickeboller, M|Tagscherer, K E|Kloor, M|Jansen, L|Chang-Claude, J|Brenner, H|Hoffmeister, M|Toth, C|Schirmacher, P|Roth, W|Blaker, H
PMID: 24662837
Journal: Leukemia. 2015 Jan;29(1):27-37.
Title: Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Author: Weisberg, Ellen|Nonami, Atsushi|Chen, Zhao|Liu, Feiyang|Zhang, Jianming|Sattler, Martin|Nelson, Erik|Cowens, Kristen|Christie, Amanda L|Mitsiades, Constantine|Wong, Kwok-Kin|Liu, Qingsong|Gray, Nathanael|Griffin, James D
PMID: 24791855
Journal: Mol Carcinog. 2015 Oct;54(10):1070-85.
Title: Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.
Author: Yaffe, Paul B|Power Coombs, Melanie R|Doucette, Carolyn D|Walsh, Mark|Hoskin, David W
PMID: 24819444
Journal: Oncogene. 2015 Apr 9;34(15):1949-60.
Title: Receptor-type protein tyrosine phosphatase kappa directly dephosphorylates CD133 and regulates downstream AKT activation.
Author: Shimozato, O|Waraya, M|Nakashima, K|Souda, H|Takiguchi, N|Yamamoto, H|Takenobu, H|Uehara, H|Ikeda, E|Matsushita, S|Kubo, N|Nakagawara, A|Ozaki, T|Kamijo, T
PMID: 24882578
Journal: Int J Biol Markers. 2015 Feb 24;30(1):e73-80.
Title: An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab.
Author: Sclafani, Francesco|Rimassa, Lorenza|Colombo, Piergiuseppe|Destro, Annarita|Stinco, Sergio|Lutman, Fabio R|Carnaghi, Carlo|Beretta, Giordano|Zanello, Alessandro|Roncalli, Massimo|Giordano, Laura|Santoro, Armando
PMID: 24980447
Journal: Arch Toxicol. 2015 Aug;89(8):1371-81.
Title: Bisphenol A modulates colorectal cancer protein profile and promotes the metastasis via induction of epithelial to mesenchymal transitions.
Author: Chen, Zhuo-Jia|Yang, Xiang-Ling|Liu, Hao|Wei, Wei|Zhang, Kun-Shui|Huang, Hong-Bin|Giesy, John P|Liu, Huan-Liang|Du, Jun|Wang, Hong-Sheng
PMID: 25119493
Journal: Cell Biochem Biophys. 2015 Jan;71(1):383-8.
Title: Knockdown of Akt2 expression by shRNA inhibits proliferation, enhances apoptosis, and increases chemosensitivity to paclitaxel in human colorectal cancer cells.
Author: Ding, Zhongyang|Xu, Fei|Li, Gan|Tang, Jiandong|Tang, Zhangfeng|Jiang, Panqiang|Wu, Haotian
PMID: 25134663
Journal: Anticancer Drugs. 2015 Jan;26(1):15-24.
Title: Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
Author: Wang, Ke|Fan, Hua|Chen, Qingsen|Ma, Guojian|Zhu, Ming|Zhang, Xiaomei|Zhang, Yuanying|Yu, Jun
PMID: 25229889
Journal: Int J Cancer. 2015 Apr 15;136(8):1967-75.
Title: Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Author: Song, Eun-Kee|Tai, W M|Messersmith, Wells A|Bagby, Stacey|Purkey, Alicia|Quackenbush, Kevin S|Pitts, Todd M|Wang, Guoliang|Blatchford, Patrick|Yahn, Rachel|Kaplan, Jeffrey|Tan, Aik Choon|Atreya, Chloe E|Eckhardt, Gail|Kelley, Robin K|Venook, Alan|Kwak, Eu
PMID: 25242168
Journal: Clin Transl Oncol. 2015 Apr;17(4):306-13.
Title: Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway.
Author: Tang, Y|Liu, P|Tian, Y|Xu, Y|Ren, F|Cui, X|Fan, J
PMID: 25257839
Journal: Tumour Biol. 2015 Feb;36(2):1091-7.
Title: Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9.
Author: E, Jifu|Xing, Junjie|Gong, Haifeng|He, Jian|Zhang, Wei
PMID: 25326806
Journal: Int J Cancer. 2015 May 15;136(10):2273-83.
Title: PINCH-2 presents functional copy number variation and suppresses migration of colon cancer cells by paracrine activity.
Author: Park, Chan Hee|Rha, Sun Young|Ahn, Joong Bae|Shin, Sang Joon|Kwon, Woo Sun|Kim, Tae Soo|An, Sungwhan|Kim, Nam Kyu|Yang, Woo-ick|Chung, Hyun Cheol
PMID: 25346044
Journal: Mol Cell Biochem. 2015 Jan;399(1-2):303-13.
Title: Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells.
Author: Umesalma, Syed|Nagendraprabhu, Ponnuraj|Sudhandiran, Ganapasam
PMID: 25355159
Journal: FASEB J. 2015 Feb;29(2):464-76.
Title: Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
Author: Alamo, Patricia|Gallardo, Alberto|Di Nicolantonio, Federica|Pavon, Miguel Angel|Casanova, Isolda|Trias, Manuel|Mangues, Maria Antonia|Lopez-Pousa, Antonio|Villaverde, Antonio|Vazquez, Esther|Bardelli, Alberto|Cespedes, Maria Virtudes|Mangues, Ramon
PMID: 25359494
Journal: Biochim Biophys Acta. 2015 Jan;1853(1):157-65.
Title: Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1alpha and beta-catenin via a p-21 activated kinase 1-dependent pathway.
Author: Huynh, Nhi|Beutler, John A|Shulkes, Arthur|Baldwin, Graham S|He, Hong
PMID: 25409929
Journal: Tumour Biol. 2015 Apr;36(4):2531-9.
Title: Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells.
Author: Zhang, Wei|Li, Qianyi|Song, Chao|Lao, Lifeng
PMID: 25427639
Journal: Tumour Biol. 2015 Mar;36(3):1477-86.
Title: MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway.
Author: Dong, Yongqiang|Liang, Guojun|Yuan, Bo|Yang, Chaoqun|Gao, Rui|Zhou, Xuhui
PMID: 25431257
Journal: Biochim Biophys Acta. 2015 Jan;1855(1):104-21.
Title: Portrait of the PI3K/AKT pathway in colorectal cancer.
Author: Danielsen, Stine Aske|Eide, Peter Wold|Nesbakken, Arild|Guren, Tormod|Leithe, Edward|Lothe, Ragnhild A
PMID: 25450577
Journal: Mol Cell Biochem. 2015 Feb;400(1-2):287-95.
Title: CXCL13-CXCR5 axis promotes the growth and invasion of colon cancer cells via PI3K/AKT pathway.
Author: Zhu, Zhenyu|Zhang, Xukui|Guo, Hongliang|Fu, Ling|Pan, Ganlin|Sun, Yinggang
PMID: 25476740
Journal: Am J Pathol. 2015 Feb;185(2):399-408.
Title: mTOR and PDGF pathway blockade inhibits liver metastasis of colorectal cancer by modulating the tumor microenvironment.
Author: Yuge, Ryo|Kitadai, Yasuhiko|Shinagawa, Kei|Onoyama, Mieko|Tanaka, Shinji|Yasui, Wataru|Chayama, Kazuaki
PMID: 25478811
Journal: Cancer Lett. 2015 Feb 28;357(2):582-90.
Title: Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.
Author: Chen, Yu-Hsuan|Wei, Ming-Feng|Wang, Chun-Wei|Lee, Hsiao-Wei|Pan, Shiow-Lin|Gao, Ming|Kuo, Sung-Hsin|Cheng, Ann-Lii|Teng, Che-Ming
PMID: 25497009
Journal: Mol Cancer Ther. 2015 Feb;14(2):480-90.
Title: Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models.
Author: Peng, Sheng-Bin|Zhang, Xiaoyi|Paul, Donald|Kays, Lisa M|Gough, Wendy|Stewart, Julie|Uhlik, Mark T|Chen, Qi|Hui, Yu-Hua|Zamek-Gliszczynski, Maciej J|Wijsman, John A|Credille, Kelly M|Yan, Liang Zeng
PMID: 25504752
Journal: Anticancer Drugs. 2015 Apr;26(4):371-8.
Title: Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
Author: Gamba, Sebastian|Camaj, Peter|Heinemann, Volker|Laubender, Rudiger P|Wang, Yan|Zhao, Yue|Stintzing, Sebastian|Giessen, Clemens|Boeck, Stefan|Haertl, Christoph|Bruns, Christiane J|Modest, Dominik P
PMID: 25514114
Journal: Ann Surg Oncol. 2015 Aug;22(8):2649-55.
Title: MiR-92a Promotes Cell Metastasis of Colorectal Cancer Through PTEN-Mediated PI3K/AKT Pathway.
Author: Ke, Tao-Wei|Wei, Po-Li|Yeh, Ken-Tu|Chen, William Tzu-Liang|Cheng, Ya-Wen
PMID: 25515201
Journal: Oncol Rep. 2015 Mar;33(3):1171-6.
Title: Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells.
Author: Moon, Ji-Hong|Jeong, Jae-Kyo|Park, Sang-Youel
PMID: 25524470
Journal: Mol Cancer Ther. 2015 Feb;14(2):620-30.
Title: IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
Author: Huang, Fei|Chang, Han|Greer, Ann|Hillerman, Stephen|Reeves, Karen A|Hurlburt, Warren|Cogswell, John|Patel, Dharmesh|Qi, Zhenhao|Fairchild, Craig|Ryseck, Rolf-Peter|Wong, Tai W|Finckenstein, Friedrich G|Jackson, Jeffrey|Carboni, Joan M
PMID: 25527633
Journal: Arch Med Res. 2015 Jan;46(1):17-23.
Title: Catechol-O-methyltransferase inhibits colorectal cancer cell proliferation and invasion.
Author: Wu, Wenming|Wu, Qiao|Hong, Xiafei|Xiong, Guangbing|Xiao, Yi|Zhou, Jiaolin|Wang, Wenze|Wu, Huanwen|Zhou, Li|Song, Wei|Dai, Hongmei|Qiu, Huizhong|Zhao, Yupei
PMID: 25532943
Journal: Mol Pharmacol. 2015;87(3):465-76.
Title: The c-MET/PI3K signaling is associated with cancer resistance to doxorubicin and photodynamic therapy by elevating BCRP/ABCG2 expression.
Author: Jung, Kyeong-Ah|Choi, Bo-Hyun|Kwak, Mi-Kyoung
PMID: 25534417
Journal: Curr Drug Targets. 2015;16(2):156-63.
Title: ATP citrate lyase (ACLY): a promising target for cancer prevention and treatment.
Author: Khwairakpam, Amrita Devi|Shyamananda, Mayengbam Singh|Sailo, Bethsebie Lalduhsaki|Rathnakaram, Sivakumar Raju|Padmavathi, Ganesan|Kotoky, Jibon|Kunnumakkara, Ajaikumar B
PMID: 25537655
Journal: Oncotarget. 2015 Mar 10;6(7):4745-56.
Title: The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells.
Author: Wei, Ning|Chu, Edward|Wu, Shao-yu|Wipf, Peter|Schmitz, John C
PMID: 25544765
Journal: Genes Dev. 2015 Jan 15;29(2):157-70.
Title: Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.
Author: Li, Nan|Zhang, Yajie|Han, Xin|Liang, Ke|Wang, Jiadong|Feng, Lin|Wang, Wenqi|Songyang, Zhou|Lin, Chunru|Yang, Liuqing|Yu, Yonghao|Chen, Junjie
PMID: 25547115
Journal: Cancer Lett. 2015 Apr 1;359(1):47-56.
Title: Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.
Author: Qazi, Asif Khurshid|Hussain, Aashiq|Khan, Saima|Aga, Mushtaq A|Behl, Akanksha|Ali, Shakir|Singh, Shashank Kumar|Taneja, Subhash Chandra|Shah, Bhahwal Ali|Saxena, Ajit Kumar|Mondhe, Dilip Manikrao|Hamid, Abid
PMID: 25554016
Journal: Cell Biochem Biophys. 2015 Jun;72(2):453-9.
Title: Sorcin Enhances Metastasis and Promotes Epithelial-to-Mesenchymal Transition of Colorectal Cancer.
Author: Tong, Weihua|Sun, Donghui|Wang, Quan|Suo, Jian
PMID: 25567655
Journal: Inflamm Bowel Dis. 2015 Feb;21(2):287-96.
Title: Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer.
Author: Khare, Vineeta|Dammann, Kyle|Asboth, Mario|Krnjic, Anita|Jambrich, Manuela|Gasche, Christoph
PMID: 25569743
Journal: Colloids Surf B Biointerfaces. 2015 Feb 1;126:322-7.
Title: Formulation of glutathione responsive anti-proliferative nanoparticles from thiolated Akt1 siRNA and disulfide-crosslinked PEI for efficient anti-cancer gene therapy.
Author: Muthiah, Muthunarayanan|Che, Hui-Lian|Kalash, Santhosh|Jo, Jihoon|Choi, Seok-Yong|Kim, Won Jong|Cho, Chong Su|Lee, Jae Young|Park, In-Kyu
PMID: 25576812
Journal: Tumour Biol. 2015 May;36(5):3903-10.
Title: Identification of cystatin SN as a novel biomarker for pancreatic cancer.
Author: Jiang, Jie|Liu, Hui-Ling|Liu, Zhi-Hao|Tan, Si-Wei|Wu, Bin
PMID: 25577248
Journal: Mol Cell Biol. 2015 Mar;35(6):988-1000.
Title: Role of microRNA 30a targeting insulin receptor substrate 2 in colorectal tumorigenesis.
Author: Zhang, Qian|Tang, Qingchao|Qin, Dandan|Yu, Lei|Huang, Rui|Lv, Guixiang|Zou, Zhaoxia|Jiang, Xiao-chen|Zou, Chendan|Liu, Wei|Luo, Jing|Zhao, Zhixun|Muhammad, Shan|Wang, Guiyu|Chen, Ying-gang|Wang, Xishan
PMID: 25582198
Journal: Cancer Lett. 2015 Apr 1;359(1):136-47.
Title: IFN-gamma-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Author: Yuan, Li|Zhou, Chang|Lu, Yanxia|Hong, Min|Zhang, Zuoyang|Zhang, Zheying|Chang, Yaya|Zhang, Chao|Li, Xuenong
PMID: 25592039
Journal: Oncotarget. 2015 Feb 20;6(5):2939-50.
Title: Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/beta-catenin pathway.
Author: Li, Dong|Liu, Wenfang|Wang, Xuan|Wu, Junlu|Quan, Wenqiang|Yao, Yiwen|Bals, Robert|Ji, Shurong|Wu, Kaiyin|Guo, Jia|Wan, Haiying
PMID: 25596747
Journal: Pathol Oncol Res. 2015 Jul;21(3):719-25.
Title: Identification of key genes associated with colorectal cancer based on the transcriptional network.
Author: Chen, Guoting|Li, Hengping|Niu, Xianping|Li, Guofeng|Han, Ning|Li, Xin|Li, Guang|Liu, Yangzhou|Sun, Guixin|Wang, Yong|Li, Zengchun|Li, Qinchuan
PMID: 25613817
Journal: Mol Med Rep. 2015 Jun;11(6):4204-10.
Title: Circadian gene hClock enhances proliferation and inhibits apoptosis of human colorectal carcinoma cells in vitro and in vivo.
Author: Wang, Yaping|Qian, Ruizhe|Sun, Ning|Lu, Chao|Chen, Zongyou|Hua, Luchun
PMID: 25625359
Journal: Mol Med Rep. 2015 Jun;11(6):4617-24.
Title: Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line.
Author: Yan, Chun-Mei|Chai, Er-Qing|Cai, Hong-Yi|Miao, Guo-Ying|Ma, Wen
PMID: 25634350
Journal: Phytomedicine. 2015 Jan 15;22(1):103-10.
Title: Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
Author: Guan, Ying-Yun|Liu, Hai-Jun|Luan, Xin|Xu, Jian-Rong|Lu, Qin|Liu, Ya-Rong|Gao, Yun-Ge|Zhao, Mei|Chen, Hong-Zhuan|Fang, Chao
PMID: 25636878
Journal: Invest New Drugs. 2015 Jun;33(3):720-8.
Title: Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer.
Author: Do, Khanh|Speranza, Giovanna|Bishop, Rachel|Khin, Sonny|Rubinstein, Larry|Kinders, Robert J|Datiles, Manuel|Eugeni, Michelle|Lam, Michael H|Doyle, L Austin|Doroshow, James H|Kummar, Shivaani
PMID: 25637165
Journal: Tumour Biol. 2015 Jun;36(6):4833-42.
Title: Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis.
Author: Qi, Hongyan|Lou, Meng|Chen, Yuexia|Liu, Xiyong|Chen, Naiming|Shan, Jianzhen|Ling, Zhiqiang|Shen, Jing|Zhu, Lijun|Yen, Yun|Zheng, Shu|Shao, Jimin
PMID: 25638032
Journal: Mol Cell Biochem. 2015 Apr;402(1-2):225-41.
Title: Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer.
Author: Rana, Chandan|Piplani, Honit|Vaish, Vivek|Nehru, Bimla|Sanyal, S N
PMID: 25644785
Journal: Oncol Rep. 2015 Apr;33(4):1579-84.
Title: Inhibitory effect of maple syrup on the cell growth and invasion of human colorectal cancer cells.
Author: Yamamoto, Tetsushi|Uemura, Kentaro|Moriyama, Kaho|Mitamura, Kuniko|Taga, Atsushi
PMID: 25647359
Journal: Int J Mol Sci. 2015 Feb 2;16(2):3202-12.
Title: Discovery of Akt kinase inhibitors through structure-based virtual screening and their evaluation as potential anticancer agents.
Author: Chuang, Chih-Hung|Cheng, Ta-Chun|Leu, Yu-Ling|Chuang, Kuo-Hsiang|Tzou, Shey-Cherng|Chen, Chien-Shu
PMID: 25648320
Journal: World J Gastroenterol. 2015 Feb 7;21(5):1488-97.
Title: MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways.
Author: Gong, Bo|Liu, Wan-Wei|Nie, Wen-Jing|Li, Dong-Feng|Xie, Zi-Jun|Liu, Chao|Liu, Yan-Hui|Mei, Ping|Li, Zi-Jun
PMID: 25663768
Journal: Cancer Lett. 2015 Apr 28;360(1):68-75.
Title: The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway.
Author: Zhou, Wei|He, Mei-Rong|Jiao, Hong-Li|He, Liu-Qing|Deng, Dan-Ling|Cai, Juan-Juan|Xiao, Zhi-Yuan|Ye, Ya-Ping|Ding, Yan-Qing|Liao, Wen-Ting|Liu, Si-De
PMID: 25667121
Journal: Oncotarget. 2015 Mar 10;6(7):5041-58.
Title: Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies.
Author: Tortolina, Lorenzo|Duffy, David J|Maffei, Massimo|Castagnino, Nicoletta|Carmody, Aimee M|Kolch, Walter|Kholodenko, Boris N|De Ambrosi, Cristina|Barla, Annalisa|Biganzoli, Elia M|Nencioni, Alessio|Patrone, Franco|Ballestrero, Alberto|Zoppoli, Gabriele|Verr
PMID: 25671297
Journal: J Med Chem. 2015 Mar 12;58(5):2452-64.
Title: Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.
Author: Ai, Yong|Kang, Fenghua|Huang, Zhangjian|Xue, Xiaowen|Lai, Yisheng|Peng, Sixun|Tian, Jide|Zhang, Yihua
PMID: 25675144
Journal: J Gastroenterol. 2015 Sep;50(9):962-74.
Title: Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model.
Author: Nakagaki, Suguru|Arimura, Yoshiaki|Nagaishi, Kanna|Isshiki, Hiroyuki|Nasuno, Masanao|Watanabe, Shuhei|Idogawa, Masashi|Yamashita, Kentaro|Naishiro, Yasuyoshi|Adachi, Yasushi|Suzuki, Hiromu|Fujimiya, Mineko|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 25680886
Journal: Oncol Rep. 2015 Apr;33(4):1828-36.
Title: Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway.
Author: Sun, Yan|Tian, Hua|Wang, Lin
PMID: 25683168
Journal: Hum Pathol. 2015 Apr;46(4):507-13.
Title: Novel molecular insights from routine genotyping of colorectal carcinomas.
Author: Stachler, Matthew D|Rinehart, Elizabeth|Lindeman, Neal|Odze, Robert|Srivastava, Amitabh
PMID: 25683705
Journal: Cancer Lett. 2015 May 28;361(1):22-32.
Title: CXCL8, overexpressed in colorectal cancer, enhances the resistance of colorectal cancer cells to anoikis.
Author: Xiao, You-Chuan|Yang, Zhi-Bin|Cheng, Xian-Shuo|Fang, Xing-Bao|Shen, Tao|Xia, Cui-Feng|Liu, Ping|Qian, Hai-Hua|Sun, Bin|Yin, Zheng-Feng|Li, Yun-Feng
PMID: 25687885
Journal: Tumour Biol. 2015 Jul;36(7):5641-8.
Title: AZD-4547 exerts potent cytostatic and cytotoxic activities against fibroblast growth factor receptor (FGFR)-expressing colorectal cancer cells.
Author: Yao, Ting-Jing|Zhu, Jin-Hai|Peng, De-Feng|Cui, Zhen|Zhang, Chao|Lu, Pei-hua
PMID: 25691251
Journal: Cancer Biol Ther. 2015;16(3):460-5.
Title: Tumor suppression by resistant maltodextrin, Fibersol-2.
Author: So, Eui Young|Ouchi, Mutsuko|Cuesta-Sancho, Sara|Olson, Susan Losee|Reif, Dirk|Shimomura, Kazuhiro|Ouchi, Toru
PMID: 25692338
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Cancer Res. 2015 Apr 1;75(7):1423-32.
Title: Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner.
Author: Prabhu, Varun V|Allen, Joshua E|Dicker, David T|El-Deiry, Wafik S
PMID: 25712124
Journal: Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title: AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author: Hechtman, Jaclyn F|Sadowska, Justyna|Huse, Jason T|Borsu, Laetitia|Yaeger, Rona|Shia, Jinru|Vakiani, Efsevia|Ladanyi, Marc|Arcila, Maria E
PMID: 25714871
Journal: Oncogene. 2015 Nov 19;34(47):5781-95.
Title: The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.
Author: Wang, J|Tang, X|Weng, W|Qiao, Y|Lin, J|Liu, W|Liu, R|Ma, L|Yu, W|Yu, Y|Pan, Q|Sun, F
PMID: 25728681
Journal: Biochem Biophys Res Commun. 2015 Apr 3;459(2):327-332.
Title: Secreted pyruvate kinase M2 facilitates cell migration via PI3K/Akt and Wnt/beta-catenin pathway in colon cancer cells.
Author: Yang, Peng|Li, Zongwei|Wang, Yingying|Zhang, Lichao|Wu, Haili|Li, Zhuoyu
PMID: 25732087
Journal: Mol Med Rep. 2015 Jul;12(1):470-4.
Title: Attenuation of enoyl coenzyme A hydratase 1 expression in colorectal cancer cells using small interfering RNA inhibits cell proliferation and migration.
Author: Zhao, Qing-Mei|Kuang, Fei|Wu, Han|Zhang, Yu-Hao
PMID: 25739098
Journal: Oncogene. 2015 Nov 19;34(47):5843-56.
Title: The DEAD box protein p68: a crucial regulator of AKT/FOXO3a signaling axis in oncogenesis.
Author: Sarkar, M|Khare, V|Guturi, K K N|Das, N|Ghosh, M K
PMID: 25745998
Journal: Oncogene. 2015 Dec 3;34(49):5971-82.
Title: An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.
Author: Zhu, G|Fan, Z|Ding, M|Zhang, H|Mu, L|Ding, Y|Zhang, Y|Jia, B|Chen, L|Chang, Z|Wu, W
PMID: 25746002
Journal: Oncotarget. 2015 Apr 10;6(10):7584-96.
Title: NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patients.
Author: Chu, Dake|Zhang, Zixi|Zhou, Yi|Li, Yunming|Zhu, Shaojun|Zhang, Jian|Zhao, Qingchuan|Ji, Gang|Wang, Weizhong|Zheng, Jianyong
PMID: 25749388
Journal: Mol Ther Nucleic Acids. 2015 Mar 10;4:e231.
Title: Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer.
Author: Hiraki, Masayuki|Nishimura, Junichi|Takahashi, Hidekazu|Wu, Xin|Takahashi, Yusuke|Miyo, Masaaki|Nishida, Naohiro|Uemura, Mamoru|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Soh, Jae-Won|Doki, Yuichiro|Mori, Masaki|Yamamoto, Hirofumi
PMID: 25756961
Journal: Int J Mol Med. 2015 May;35(5):1301-8.
Title: miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway.
Author: Zhang, Xiangliang|Shi, Huijuan|Tang, Hongsheng|Fang, Zhiyuan|Wang, Jiping|Cui, Shuzhong
PMID: 25760926
Journal: Sci Rep. 2015 Mar 12;5:9054.
Title: The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.
Author: Maione, Federica|Oliaro-Bosso, Simonetta|Meda, Claudia|Di Nicolantonio, Federica|Bussolino, Federico|Balliano, Gianni|Viola, Franca|Giraudo, Enrico
PMID: 25761781
Journal: Nutrients. 2015 Mar 10;7(3):1696-715.
Title: Strawberry phytochemicals inhibit azoxymethane/dextran sodium sulfate-induced colorectal carcinogenesis in Crj: CD-1 mice.
Author: Shi, Ni|Clinton, Steven K|Liu, Zhihua|Wang, Yongquan|Riedl, Kenneth M|Schwartz, Steven J|Zhang, Xiaoli|Pan, Zui|Chen, Tong
PMID: 25763529
Journal: Biomol Ther (Seoul). 2015 Mar;23(2):128-33.
Title: The Cytotoxicity of Kahweol in HT-29 Human Colorectal Cancer Cells Is Mediated by Apoptosis and Suppression of Heat Shock Protein 70 Expression.
Author: Choi, Dong Wook|Lim, Man Sup|Lee, Jae Won|Chun, Wanjoo|Lee, Sang Hyuk|Nam, Yang Hoon|Park, Jin Myung|Choi, Dae Hee|Kang, Chang Don|Lee, Sung Joon|Park, Sung Chul
PMID: 25767680
Journal: Biomol Ther (Seoul). 2015 Mar;23(2):134-40.
Title: ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells.
Author: Kim, Kui-Jin|Lee, Jihye|Park, Yeonhwa|Lee, Seong-Ho
PMID: 25767681
Journal: J Cell Biochem. 2015 Sep;116(9):1837-47.
Title: Oncogenic and Therapeutic Targeting of PTEN Loss in Bone Malignancies.
Author: Xi, Yongming|Chen, Yan
PMID: 25773992
Journal: PLoS One. 2015 Mar 16;10(3):e0119524.
Title: Repulsive axon guidance by Draxin is mediated by protein Kinase B (Akt), glycogen synthase kinase-3beta (GSK-3beta) and microtubule-associated protein 1B.
Author: Meli, Rajeshwari|Weisova, Petronela|Propst, Friedrich
PMID: 25775433
Journal: Mol Med Rep. 2015 Jul;12(1):1189-96.
Title: Nitrogen permease regulator-like 2 enhances sensitivity to oxaliplatin in colon cancer cells.
Author: Liu, Ming-Na|Liu, Ai-Yun|Du, Ya-Ju|Pei, Feng-Hua|Wang, Xin-Hong|Chen, Jing|Liu, Dan|Liu, Bing-Rong
PMID: 25777765
Journal: Eur J Pharmacol. 2015 Jun 15;757:21-7.
Title: Quinaldic acid inhibits proliferation of colon cancer ht-29 cells in vitro: effects on signaling pathways.
Author: Langner, Ewa|Walczak, Katarzyna|Jeleniewicz, Witold|Turski, Waldemar A|Rajtar, Grazyna
PMID: 25797283
Journal: Gastroenterology. 2015 Jul;149(1):177-189.e10.
Title: VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.
Author: Foersch, Sebastian|Sperka, Tobias|Lindner, Christina|Taut, Astrid|Rudolph, Karl L|Breier, Georg|Boxberger, Frank|Rau, Tilman T|Hartmann, Arndt|Sturzl, Michael|Wittkopf, Nadine|Haep, Lisa|Wirtz, Stefan|Neurath, Markus F|Waldner, Maximilian J
PMID: 25797700
Journal: Sci Rep. 2015 Mar 24;5:9429.
Title: HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.
Author: Feng, Yingying|Xu, Xiaojie|Zhang, Yunjing|Ding, Jianhua|Wang, Yonggang|Zhang, Xiaopeng|Wu, Zhe|Kang, Lei|Liang, Yingchun|Zhou, LiYing|Song, Santai|Zhao, Ke|Ye, Qinong
PMID: 25800793
Journal: Cancer Biol Ther. 2015;16(5):733-42.
Title: Differential regulation of autophagy and cell viability by ceramide species.
Author: Cruickshanks, Nichola|Roberts, Jane L|Bareford, M Danielle|Tavallai, Mehrad|Poklepovic, Andrew|Booth, Laurence|Spiegel, Sarah|Dent, Paul
PMID: 25803131
Journal: Int J Cancer. 2015 Oct 1;137(7):1560-73.
Title: Sialidase NEU3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating Wnt signaling.
Author: Takahashi, Kohta|Hosono, Masahiro|Sato, Ikuro|Hata, Keiko|Wada, Tadashi|Yamaguchi, Kazunori|Nitta, Kazuo|Shima, Hiroshi|Miyagi, Taeko
PMID: 25810027
Journal: Cell Physiol Biochem. 2015;35(5):1821-30.
Title: Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
Author: Yun, Miyong|Lee, Duckgue|Park, Moon-Nyeo|Kim, Eun-Ok|Sohn, Eun Jung|Kwon, Byung-Mog|Kim, Sung-Hoon
PMID: 25833196
Journal: Clin Cancer Res. 2015 Jul 1;21(13):2975-83.
Title: Primary and Acquired Resistance of Colorectal Cancer to Anti-EGFR Monoclonal Antibody Can Be Overcome by Combined Treatment of Regorafenib with Cetuximab.
Author: Napolitano, Stefania|Martini, Giulia|Rinaldi, Barbara|Martinelli, Erika|Donniacuo, Maria|Berrino, Liberato|Vitagliano, Donata|Morgillo, Floriana|Barra, Giusy|De Palma, Raffaele|Merolla, Francesco|Ciardiello, Fortunato|Troiani, Teresa
PMID: 25838391
Journal: J Pathol. 2015 Aug;236(4):467-78.
Title: SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis.
Author: Zhou, Zhi-hang|Rao, Jun|Yang, Jing|Wu, Feng|Tan, Juan|Xu, Sen-lin|Ding, Yanqing|Zhan, Na|Hu, Xu-gang|Cui, You-hong|Zhang, Xia|Dong, Weiguo|Liu, Xin-dong|Bian, Xiu-wu
PMID: 25866254
Journal: Cell Physiol Biochem. 2015;35(5):2069-77.
Title: Genistein inhibits human colorectal cancer growth and suppresses miR-95, Akt and SGK1.
Author: Qin, Jian|Chen, Jia Xin|Zhu, Zhou|Teng, Jia An
PMID: 25871428
Journal: J Biol Chem. 2015 Jun 12;290(24):15018-29.
Title: Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-kappaB Pathway.
Author: Zhang, Ling-Li|Mu, Gang-Gang|Ding, Qian-Shan|Li, Yan-Xia|Shi, Yun-bo|Dai, Jin-Fen|Yu, Hong-Gang
PMID: 25873394
Journal: Endocr Relat Cancer. 2015 Jun;22(3):455-64.
Title: Brain-derived neurotrophic factor regulates cell motility in human colon cancer.
Author: Huang, Ssu-Ming|Lin, Chingju|Lin, Hsiao-Yun|Chiu, Chien-Ming|Fang, Chia-Wei|Liao, Kuan-Fu|Chen, Dar-Ren|Yeh, Wei-Lan
PMID: 25876647
Journal: BMC Cancer. 2015 Mar 4;15:90.
Title: Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancer.
Author: Wang, Jianwei|Yu, Shaojun|Cui, Liming|Wang, Wenhui|Li, Jun|Wang, Ke|Lao, Xinyuan
PMID: 25884313
Journal: J Hematol Oncol. 2015 Mar 15;8:26.
Title: Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author: Wang, He|Yang, Shu|Zhou, Hong|Sun, Mingna|Du, Lingran|Wei, Minyan|Luo, Meixia|Huang, Jingzhu|Deng, Hongzhu|Feng, Yinghong|Huang, Jun|Zhou, Yi
PMID: 25886453
Journal: J Transl Med. 2015 Feb 12;13:57.
Title: Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib.
Author: Wong, Andrea Li Ann|Lim, Joline Si Jing|Sinha, Arvind|Gopinathan, Anil|Lim, Robert|Tan, Chee-Seng|Soh, Thomas|Venkatesh, Sudhakar|Titin, Christina|Sapari, Nur Sabrina|Lee, Soo-Chin|Yong, Wei-Peng|Tan, David Shao Ping|Pang, Brendan|Wang, Ting-Ting|Zee, Yin
PMID: 25889309
Journal: Nutr J. 2015 Apr 1;14:31.
Title: Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells.
Author: Tahir, Analhuda Abdullah|Sani, Nur Fathiah Abdul|Murad, Noor Azian|Makpol, Suzana|Ngah, Wan Zurinah Wan|Yusof, Yasmin Anum Mohd
PMID: 25889965
Journal: Int J Oncol. 2015;46(6):2670-8.
Title: The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells.
Author: Hyun, Hwang-Bo|Lee, Won Sup|Go, Se-Il|Nagappan, Arulkumar|Park, Cheol|Han, Min Ho|Hong, Su Hyun|Kim, Gonsup|Kim, Gi Young|Cheong, Jaehun|Ryu, Chung Ho|Shin, Sung Chul|Choi, Yung Hyun
PMID: 25892545
Journal: J Cell Physiol. 2015 Dec;230(12):2973-80.
Title: Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines.
Author: Refolo, Maria Grazia|D'Alessandro, Rosalba|Malerba, Natascia|Laezza, Chiara|Bifulco, Maurizio|Messa, Caterina|Caruso, Maria Gabriella|Notarnicola, Maria|Tutino, Valeria
PMID: 25893829
Journal: Oncotarget. 2015 Jun 20;6(17):15332-47.
Title: Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
Author: Sharon, Chetna|Baranwal, Somesh|Patel, Nirmita J|Rodriguez-Agudo, Daniel|Pandak, William M|Majumdar, Adhip P N|Krystal, Geoffrey|Patel, Bhaumik B
PMID: 25895029
Journal: Cancer Res. 2015 Jun 15;75(12):2434-44.
Title: IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Author: Bartolome, Ruben A|Garcia-Palmero, Irene|Torres, Sofia|Lopez-Lucendo, Maria|Balyasnikova, Irina V|Casal, J Ignacio
PMID: 25896327
Journal: PLoS One. 2015 Apr 23;10(4):e0119015.
Title: mLST8 Promotes mTOR-Mediated Tumor Progression.
Author: Kakumoto, Kyoko|Ikeda, Jun-Ichiro|Okada, Masato|Morii, Eiichi|Oneyama, Chitose
PMID: 25906254
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Apr;35(4):511-5.
Title: [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells].
Author: Liu, Jin-Kun|Hao, Ya-Juan|Huang, Jia-Wei|Li, Xin|Cai, Hong-Bing|Peng, Kang
PMID: 25907934
Journal: Tumori. 2015 Mar-Apr;101(2):238-45.
Title: BDE-99 (2,2',4,4',5-pentabromodiphenyl ether) triggers epithelial-mesenchymal transition in colorectal cancer cells via PI3K/Akt/Snail signaling pathway.
Author: Wang, Fei|Ruan, Xin-Jian|Zhang, Hong-Yan
PMID: 25908029
Journal: Int J Nanomedicine. 2015 Apr 8;10:2823-46.
Title: Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene.
Author: Huang, Rwei-Fen S|Wei, Yi-Jun|Inbaraj, Baskaran Stephen|Chen, Bing-Huei
PMID: 25914533
Journal: Carcinogenesis. 2015 Jul;36(7):710-8.
Title: ERBB4 is over-expressed in human colon cancer and enhances cellular transformation.
Author: Williams, Christopher S|Bernard, Jessica K|Demory Beckler, Michelle|Almohazey, Dana|Washington, Mary Kay|Smith, Jesse J|Frey, Mark R
PMID: 25916654
Journal: Br J Cancer. 2015 Apr 28;112(9):1480-90.
Title: MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms.
Author: Amankwatia, E B|Chakravarty, P|Carey, F A|Weidlich, S|Steele, R J C|Munro, A J|Wolf, C R|Smith, G
PMID: 25919696
Journal: J Surg Oncol. 2015 Jun;111(7):905-10.
Title: Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers.
Author: Lan, Yuan-Tzu|Jen-Kou, Lin|Lin, Chien-Hsing|Yang, Shung-Haur|Lin, Chun-Chi|Wang, Huann-Sheng|Chen, Wei-Shone|Lin, Tzu-Chen|Jiang, Jeng-Kai|Chang, Shih-Ching
PMID: 25920435
Journal: Asian Pac J Cancer Prev. 2015;16(8):3395-402.
Title: Microarray Analysis of Long Non-coding RNA Expression Profile Associated with 5-Fluorouracil-Based Chemoradiation Resistance in Colorectal Cancer Cells.
Author: Xiong, Wei|Jiang, Yong-Xin|Ai, Yi-Qin|Liu, Shan|Wu, Xing-Rao|Cui, Jian-Guo|Qin, Ji-Yong|Liu, Yan|Xia, Yao-Xiong|Ju, Yun-He|He, Wen-Jie|Wang, Yong|Li, Yun-Fen|Hou, Yu|Wang, Li|Li, Wen-Hui
PMID: 25921151
Journal: Mol Cancer. 2015 Apr 28;14:95.
Title: High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma.
Author: Li, Xinxiang|Liang, Lei|Huang, Liyong|Ma, Xiaoji|Li, Dawei|Cai, Sanjun
PMID: 25927939
Journal: Cell Signal. 2015 Aug;27(8):1557-68.
Title: Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
Author: Bommer, Ulrich-Axel|Iadevaia, Valentina|Chen, Jiezhong|Knoch, Bianca|Engel, Martin|Proud, Christopher G
PMID: 25936523
Journal: Oncotarget. 2015 Jun 20;6(17):15222-34.
Title: MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling.
Author: Huang, Na|Wu, Zhenzhen|Lin, Li|Zhou, Minyu|Wang, Lin|Ma, Huanrong|Xia, Jianling|Bin, Jianping|Liao, Yulin|Liao, Wangjun
PMID: 25945841
Journal: PLoS One. 2015 May 7;10(5):e0121648.
Title: ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/beta-Catenin, Notch and PI3K/Akt Signaling Pathways.
Author: Singh, Surendra|Arcaroli, John|Chen, Ying|Thompson, David C|Messersmith, Wells|Jimeno, Antonio|Vasiliou, Vasilis
PMID: 25950950
Journal: Oncotarget. 2015 Jun 10;6(16):13962-77.
Title: AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
Author: Mi, Wenting|Ye, Qing|Liu, Side|She, Qing-Bai
PMID: 25961827
Journal: Oncotarget. 2015 Jun 10;6(16):14385-98.
Title: PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer.
Author: Wang, Huanan|Zhang, Lingling|Yang, Xu|Jin, Yipeng|Pei, Shimin|Zhang, Di|Zhang, Hong|Zhou, Bin|Zhang, Yingjie|Lin, Degui
PMID: 25965911
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1402-10. eCollection 2015.
Title: Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target.
Author: Liu, Guiyuan|Song, Yang|Cui, Lianhua|Wen, Zhaoxia|Lu, Xiaoqing
PMID: 25973024
Journal: Biomol Ther (Seoul). 2015 May;23(3):225-32.
Title: Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling.
Author: Han, Yong-Seok|Lee, Jun Hee|Lee, Sang Hun
PMID: 25995820
Journal: Mol Med Rep. 2015 Sep;12(3):3446-3452.
Title: Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways.
Author: Han, Yong-Seok|Lee, Jun Hee|Lee, Sang Hun
PMID: 25998232
Journal: Biochem Biophys Res Commun. 2015 Jul 31;463(3):229-34.
Title: Chemoresistance of CD133(+) colon cancer may be related with increased survivin expression.
Author: Lee, Mi-Ra|Ji, Sun-Young|Mia-Jan, Khalilullah|Cho, Mee-Yon
PMID: 26002465
Journal: Cancer Sci. 2015 Aug;106(8):1000-7.
Title: Atonal homolog 1 protein stabilized by tumor necrosis factor alpha induces high malignant potential in colon cancer cell line.
Author: Fukushima, Keita|Tsuchiya, Kiichiro|Kano, Yoshihito|Horita, Nobukatsu|Hibiya, Shuji|Hayashi, Ryohei|Kitagaki, Keisuke|Negi, Mariko|Itoh, Eisaku|Akashi, Takumi|Eishi, Yoshinobu|Oshima, Shigeru|Nagaishi, Takashi|Okamoto, Ryuichi|Nakamura, Tetsuya|Watanabe,
PMID: 26017781
Journal: Cell Cycle. 2015;14(16):2667-76.
Title: Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation.
Author: Fazolini, Narayana P B|Cruz, Andre L S|Werneck, Miriam B F|Viola, Joao P B|Maya-Monteiro, Clarissa M|Bozza, Patricia T
PMID: 26017929
Journal: Drug Resist Updat. 2015 May;20:39-70.
Title: Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.
Author: De Mattia, Elena|Cecchin, Erika|Toffoli, Giuseppe
PMID: 26027741
Journal: Oncotarget. 2015 May 10;6(13):10994-1008.
Title: Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway.
Author: Conti, Annalisa|Majorini, Maria Teresa|Elliott, Richard|Ashworth, Alan|Lord, Christopher J|Cancelliere, Carlotta|Bardelli, Alberto|Seneci, Pierfausto|Walczak, Henning|Delia, Domenico|Lecis, Daniele
PMID: 26028667
Journal: BMC Cancer. 2015 Jun 5;15:456.
Title: Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour.
Author: Cardoso, Ana P|Pinto, Marta L|Pinto, Ana T|Pinto, Marta T|Monteiro, Catia|Oliveira, Marta I|Santos, Susana G|Relvas, Joao B|Seruca, Raquel|Mantovani, Alberto|Mareel, Marc|Barbosa, Mario A|Oliveira, Maria J
PMID: 26043921
Journal: Mol Med Rep. 2015 Sep;12(3):3487-3493.
Title: Functional characterization of the nitrogen permease regulator-like-2 candidate tumor suppressor gene in colorectal cancer cell lines.
Author: Liu, Ai-Yun|Liu, Ming-Na|Pei, Feng-Hua|Chen, Jing|Wang, Xin-Hong|Liu, Dan|Du, Ya-Ju|Liu, Bing-Rong
PMID: 26044952
Journal: Int J Clin Exp Pathol. 2015 Mar 1;8(3):2809-15. eCollection 2015.
Title: CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro.
Author: Zhong, Gang|Li, Huikai|Shan, Tao|Zhang, Nan
PMID: 26045788
Journal: Am J Cancer Res. 2015 Feb 15;5(3):1047-61. eCollection 2015.
Title: Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.
Author: Xie, Jing|Gao, Hui|Peng, Jianjun|Han, Yantao|Chen, Xuehong|Jiang, Qixiao|Wang, Chunbo
PMID: 26045985
Journal: BMC Gastroenterol. 2015 Jun 6;15:64.
Title: Gene expression profiling of laterally spreading tumors.
Author: Minemura, Shoko|Tanaka, Takeshi|Arai, Makoto|Okimoto, Kenichiro|Oyamada, Arata|Saito, Keiko|Maruoka, Daisuke|Matsumura, Tomoaki|Nakagawa, Tomoo|Katsuno, Tatsuro|Kishimoto, Takashi|Yokosuka, Osamu
PMID: 26048755
Journal: J Bioenerg Biomembr. 2015 Aug;47(4):319-29.
Title: Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer.
Author: Sun, Yiming|Liu, Zhe|Zou, Xue|Lan, Yadong|Sun, Xiaojin|Wang, Xiu|Zhao, Surong|Jiang, Chenchen|Liu, Hao
PMID: 26054380
Journal: Gastroenterology. 2015 Oct;149(4):981-92.e11.
Title: MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.
Author: Polytarchou, Christos|Hommes, Daniel W|Palumbo, Tiziana|Hatziapostolou, Maria|Koutsioumpa, Marina|Koukos, Georgios|van der Meulen-de Jong, Andrea E|Oikonomopoulos, Angelos|van Deen, Welmoed K|Vorvis, Christina|Serebrennikova, Oksana B|Birli, Eleni|Choi, J
PMID: 26055138
Journal: Med Oncol. 2015 Jul;32(7):198.
Title: Expression of 3-phosphoinositide-dependent protein kinase 1 in colorectal cancer as a potential therapeutic target.
Author: Xu, Zhenglei|Liao, Bihong|Zhang, Ru|Yao, Jun|Shi, Ruiyue|Wang, Lisheng
PMID: 26055151
Journal: Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2570-9.
Title: TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways.
Author: Agliarulo, Ilenia|Matassa, Danilo Swann|Amoroso, Maria Rosaria|Maddalena, Francesca|Sisinni, Lorenza|Sepe, Leandra|Ferrari, Maria Carla|Arzeni, Diana|Avolio, Rosario|Paolella, Giovanni|Landriscina, Matteo|Esposito, Franca
PMID: 26071104
Journal: BMC Cancer. 2015 Jun 16;15:471.
Title: The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma.
Author: Chen, Shuo|Gou, Wen-Feng|Zhao, Shuang|Niu, Zhe-Feng|Zhao, Yang|Takano, Yasuo|Zheng, Hua-Chuan
PMID: 26077911
Journal: Radiother Oncol. 2015 Sep;116(3):510-6.
Title: EGFR and beta1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion.
Author: Poschau, Mandy|Dickreuter, Ellen|Singh-Muller, Jenny|Zscheppang, Katja|Eke, Iris|Liersch, Torsten|Cordes, Nils
PMID: 26096850
Journal: PLoS One. 2015 Jun 22;10(6):e0131108.
Title: A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer.
Author: Arvai, Kevin J|Hsu, Ya-Hsuan|Lee, Lobin A|Jones, Dan
PMID: 26098881
Journal: Expert Opin Ther Targets. 2015;19(8):1017-26.
Title: MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.
Author: Mussnich, Paula|Rosa, Roberta|Bianco, Roberto|Fusco, Alfredo|D'Angelo, Daniela
PMID: 26107137
Journal: Nat Med. 2015 Aug;21(8):906-13.
Title: Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Author: Wilson, Justin E|Petrucelli, Alex S|Chen, Liang|Koblansky, A Alicia|Truax, Agnieszka D|Oyama, Yoshitaka|Rogers, Arlin B|Brickey, W June|Wang, Yuli|Schneider, Monika|Muhlbauer, Marcus|Chou, Wei-Chun|Barker, Brianne R|Jobin, Christian|Allbritton, Nancy L|Ra
PMID: 26107252
Journal: Cancer Invest. 2015;33(8):387-97.
Title: Focal Adhesion Proteins alpha- and beta-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression.
Author: Bravou, Vasiliki|Antonacopoulou, Anna|Papanikolaou, Sofia|Nikou, Sofia|Lilis, Ioannis|Giannopoulou, Efstathia|Kalofonos, Haralabos P
PMID: 26115385
Journal: Cancer Chemother Pharmacol. 2015 Sep;76(3):471-9.
Title: NECTIN-4 increased the 5-FU resistance in colon cancer cells by inducing the PI3K-AKT cascade.
Author: Das, Dipon|Satapathy, Shakti Ranjan|Siddharth, Sumit|Nayak, Anmada|Kundu, Chanakya Nath
PMID: 26122960
Journal: Elife. 2015 Jun 30;4:e07091.
Title: Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling.
Author: Aznar, Nicolas|Midde, Krishna K|Dunkel, Ying|Lopez-Sanchez, Inmaculada|Pavlova, Yelena|Marivin, Arthur|Barbazan, Jorge|Murray, Fiona|Nitsche, Ulrich|Janssen, Klaus-Peter|Willert, Karl|Goel, Ajay|Abal, Miguel|Garcia-Marcos, Mikel|Ghosh, Pradipta
PMID: 26126266
Journal: Cancer Immunol Res. 2015 Nov;3(11):1227-35.
Title: IL10R2 Overexpression Promotes IL22/STAT3 Signaling in Colorectal Carcinogenesis.
Author: Khare, Vineeta|Paul, Gregor|Movadat, Oliver|Frick, Adrian|Jambrich, Manuela|Krnjic, Anita|Marian, Brigitte|Wrba, Friedrich|Gasche, Christoph
PMID: 26130064
Journal: Oncol Rep. 2015 Sep;34(3):1178-84.
Title: Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
Author: Jin, Soojung|Yun, Hee Jung|Jeong, Hyun Young|Oh, You Na|Park, Hyun-Jin|Yun, Seung-Geun|Kim, Byung Woo|Kwon, Hyun Ju
PMID: 26133679
Journal: Int J Cancer. 2015 Dec 15;137(12):2803-14.
Title: Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.
Author: Zhang, Xuemei|Ai, Feiyan|Li, Xiayu|She, Xiaoling|Li, Nan|Tang, Anliu|Qin, Zailong|Ye, Qiurong|Tian, Li|Li, Guiyuan|Shen, Shourong|Ma, Jian
PMID: 26135667
Journal: Mol Cancer. 2015 Jul 10;14:131.
Title: Co-targeting of Cyclooxygenase-2 and FoxM1 is a viable strategy in inducing anticancer effects in colorectal cancer cells.
Author: Ahmed, Maqbool|Hussain, Azhar R|Siraj, Abdul K|Uddin, Shahab|Al-Sanea, Nasser|Al-Dayel, Fouad|Al-Assiri, Mohammed|Beg, Shaham|Al-Kuraya, Khawla S
PMID: 26159723
Journal: Biochem Biophys Res Commun. 2015 Aug 21;464(2):519-25.
Title: LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic silenced gene in colorectal cancer.
Author: Kou, Changhua|Zhou, Tian|Han, Xilin|Zhuang, Huijie|Qian, Haixin
PMID: 26159916
Journal: Oncotarget. 2015 Sep 15;6(27):24148-62.
Title: Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.
Author: Chen, Guo-Qing|Tang, Cheng-Fang|Shi, Xiao-Ke|Lin, Cheng-Yuan|Fatima, Sarwat|Pan, Xiao-Hua|Yang, Da-Jian|Zhang, Ge|Lu, Ai-Ping|Lin, Shu-Hai|Bian, Zhao-Xiang
PMID: 26160839
Journal: Oncotarget. 2015 Jul 10;6(19):16902-11.
Title: ErbB-3 activation by NRG-1beta sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).
Author: Prasetyanti, Pramudita R|Capone, Emily|Barcaroli, Daniela|D'Agostino, Daniela|Volpe, Silvia|Benfante, Antonina|van Hooff, Sander|Iacobelli, Valentina|Rossi, Cosmo|Iacobelli, Stefano|Medema, Jan Paul|De Laurenzi, Vincenzo|Sala, Gianluca
PMID: 26160848
Journal: Anal Bioanal Chem. 2015 Nov;407(27):8321-31.
Title: In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.
Author: Yosef, Hesham K|Mavarani, Laven|Maghnouj, Abdelouahid|Hahn, Stephan|El-Mashtoly, Samir F|Gerwert, Klaus
PMID: 26168967
Journal: Mol Cell Biochem. 2015 Oct;408(1-2):205-13.
Title: Derlin-1 is overexpressed in human colon cancer and promotes cancer cell proliferation.
Author: Tan, Xueming|He, Xiaolu|Jiang, Zhonghua|Wang, Xiaohong|Ma, Limei|Liu, Li|Wang, Xiang|Fan, Zhining|Su, Dongming
PMID: 26173415
Journal: Int J Clin Exp Pathol. 2015 May 1;8(5):4481-91. eCollection 2015.
Title: Up-regulation of microRNA-302a inhibited the proliferation and invasion of colorectal cancer cells by regulation of the MAPK and PI3K/Akt signaling pathways.
Author: Wei, Zhi-Jiang|Tao, Ming-Ling|Zhang, Wei|Han, Guo-Da|Zhu, Zhong-Cheng|Miao, Zhi-Gang|Li, Jian-Ye|Qiao, Zhan-Bing
PMID: 26191138
Journal: Cell Mol Biol Lett. 2015 Mar;20(1):38-47.
Title: Cyclic phosphatidic acid induces G0/G1 arrest, inhibits AKT phosphorylation, and downregulates cyclin D1 expression in colorectal cancer cells.
Author: Tsukahara, Tamotsu|Haniu, Hisao|Matsuda, Yoshikazu
PMID: 26204392
Journal: Biochem Pharmacol. 2015 Sep 1;97(1):27-37.
Title: Vatalanib sensitizes ABCB1 and ABCG2-overexpressing multidrug resistant colon cancer cells to chemotherapy under hypoxia.
Author: To, Kenneth K W|Poon, Daniel C|Wei, Yuming|Wang, Fang|Lin, Ge|Fu, Li-wu
PMID: 26206183
Journal: Biomed Pharmacother. 2015 Jul;73:12-8.
Title: Knockdown of type I insulin-like growth factor receptor inhibits human colorectal cancer cell growth and downstream PI3K/Akt, WNT/beta-catenin signal pathways.
Author: Zhang, Qian-yun|Wang, Lu|Song, Zhi-yu|Qu, Xian-jun
PMID: 26211576
Journal: Anticancer Drugs. 2015 Sep;26(8):813-23.
Title: Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells.
Author: Fan, Kai|Li, Xiaolei|Cao, Yonggang|Qi, Hanping|Li, Lei|Zhang, Qianhui|Sun, Hongli
PMID: 26214321
Journal: Toxicol Appl Pharmacol. 2015 Oct 15;288(2):232-9.
Title: Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-kappaB signalings in colorectal cancer cells.
Author: Wang, Lei|Hitron, John Andrew|Wise, James T F|Son, Young-Ok|Roy, Ram Vinod|Kim, Donghern|Dai, Jin|Pratheeshkumar, Poyil|Zhang, Zhuo|Xu, Mei|Luo, Jia|Shi, Xianglin
PMID: 26220687
Journal: Anticancer Drugs. 2015 Oct;26(9):964-73.
Title: The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment.
Author: Tian, Shaobo|Chang, Weilong|Du, Hansong|Bai, Jie|Sun, Zhenhai|Zhang, Qing|Wang, Hui|Zhu, Guangsheng|Tao, Kaixiong|Long, Yueping
PMID: 26225471
Journal: Cancer Cell Int. 2015 Aug 1;15:77.
Title: Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells.
Author: Tao, Yi-Jing|Li, Yong-Ju|Zheng, Wen|Zhao, Juan-Juan|Guo, Meng-Meng|Zhou, Ya|Qin, Na-Lin|Zheng, Jing|Xu, Lin
PMID: 26236156
Journal: J Transl Med. 2015 Aug 4;13:252.
Title: MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer.
Author: Zheng, Lin|Zhang, Yuqin|Liu, Yan|Zhou, Min|Lu, Yanxia|Yuan, Li|Zhang, Chao|Hong, Min|Wang, Shuang|Li, Xuenong
PMID: 26238857
Journal: Mol Med Rep. 2015 Oct;12(4):5816-20.
Title: Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis.
Author: Du, Jie|Chen, Chunyou|Sun, Yiqun|Zheng, Lin|Wang, Wanchen
PMID: 26239027
Journal: Growth Horm IGF Res. 2015 Oct;25(5):253-61.
Title: Crosstalk between the TNF and IGF pathways enhances NF-kappaB activation and signaling in cancer cells.
Author: Li, Shun|Pinard, Maxime|Wang, Yunling|Yang, Long|Lin, Rongtuan|Hiscott, John|Su, Bing|Brodt, Pnina
PMID: 26239406
Journal: Cell Death Dis. 2015 Aug 6;6:e1845.
Title: MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer.
Author: Zhang, Yang|Talmon, G|Wang, J
PMID: 26247730
Journal: PLoS One. 2015 Aug 10;10(8):e0134948.
Title: Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.
Author: Chung, Seyung|Dwabe, Sami|Elshimali, Yayha|Sukhija, Hemlata|Aroh, Clement|Vadgama, Jaydutt V
PMID: 26258407
Journal: Oncogenesis. 2015 Aug 10;4:e162.
Title: SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
Author: Tiwari, R|Pandey, S K|Goel, S|Bhatia, V|Shukla, S|Jing, X|Dhanasekaran, S M|Ateeq, B
PMID: 26258891
Journal: Redox Biol. 2015 Dec;6:218-25.
Title: Influence of myeloperoxidase on colon tumor occurrence in inflamed versus non-inflamed colons of Apc(Min/+) mice.
Author: Al-Salihi, Mazin|Reichert, Ethan|Fitzpatrick, F A
PMID: 26262998
Journal: Am J Cancer Res. 2015 May 15;5(6):2022-34. eCollection 2015.
Title: Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition.
Author: Li, Qingguo|Wu, Jitao|Wei, Ping|Xu, Ye|Zhuo, Changhua|Wang, Yuwei|Li, Dawei|Cai, Sanjun
PMID: 26269761
Journal: J Cancer. 2015 Jul 15;6(9):825-31.
Title: Hypothesis: Obesity Is Associated with a Lower Mutation Threshold in Colon Cancer.
Author: Bordonaro, Michael|Lazarova, Darina
PMID: 26284133
Journal: Mol Med Rep. 2015 Oct;12(4):5939-44.
Title: Colchicine induces apoptosis in HT29 human colon cancer cells via the AKT and c-Jun N-terminal kinase signaling pathways.
Author: Huang, Zhen|Xu, Ye|Peng, Wei
PMID: 26299305
Journal: Food Chem Toxicol. 2015 Oct;84:125-32.
Title: Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
Author: Cerezo-Guisado, Maria Isabel|Zur, Rafal|Lorenzo, Maria Jesus|Risco, Ana|Martin-Serrano, Miguel A|Alvarez-Barrientos, Alberto|Cuenda, Ana|Centeno, Francisco
PMID: 26303273
Journal: Cancer Prev Res (Phila). 2015 Nov;8(11):1093-101.
Title: PAK1 promotes intestinal tumor initiation.
Author: Dammann, Kyle|Khare, Vineeta|Harpain, Felix|Lang, Michaela|Kurtovic, Azra|Mesteri, Ildiko|Evstatiev, Rayko|Gasche, Christoph
PMID: 26304465
Journal: Eur J Pharmacol. 2015 Oct 15;765:217-27.
Title: Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
Author: Pal, Ipsita|Parida, Sheetal|Prashanth Kumar, B N|Banik, Payel|Kumar Dey, Kaushik|Chakraborty, Sandipan|Bhutia, Sujit K|Mandal, Mahitosh
PMID: 26306675
Journal: Exp Cell Res. 2015 Oct 15;338(1):10-21.
Title: Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells.
Author: Coskun, Deniz|Obakan, Pinar|Arisan, Elif Damla|Coker-Gurkan, Ajda|Palavan-Unsal, Narcin
PMID: 26318418
Journal: Biomaterials. 2015 Dec;71:84-99.
Title: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Author: Roy, Kislay|Kanwar, Rupinder K|Kanwar, Jagat R
PMID: 26318819
Journal: Bioorg Med Chem Lett. 2015 Oct 1;25(19):4287-92.
Title: Probing a 3,4'-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway.
Author: Diez-Cecilia, Elena|Carson, Robert|Kelly, Brendan|van Schaeybroeck, Sandra|Murray, James T|Rozas, Isabel
PMID: 26318998
Journal: Gastroenterol Hepatol Bed Bench. 2015 Summer;8(3):215-24.
Title: Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer.
Author: Zamanian-Azodi, Mona|Rezaei-Tavirani, Mostafa|Rahmati-Rad, Sara|Hasanzadeh, Hadi|Rezaei Tavirani, Majid|Seyyedi, Samaneh Sadat
PMID: 26328044
Journal: Oncol Rep. 2015 Nov;34(5):2557-66.
Title: Downregulation of VMP1 confers aggressive properties to colorectal cancer.
Author: Guo, Xian-Zhi|Ye, Xiao-Lei|Xiao, Wei-Zhong|Wei, Xue-Ni|You, Qing-Hua|Che, Xiao-Hang|Cai, Yan-Jun|Chen, Fang|Yuan, Hao|Liu, Xiao-Jian|Yu, Ming-Hua
PMID: 26328607
Journal: Int J Gynecol Cancer. 2015 Oct;25(8):1353-63.
Title: Metastasis-Associated in Colon Cancer-1 Associates With Poor Prognosis and Promotes Cell Invasion and Angiogenesis in Human Cervical Cancer.
Author: Zhou, Xiang|Xu, Chang-Juan|Wang, Jun-Xian|Dai, Ting|Ye, Ya-Ping|Cui, Yan-Mei|Liao, Wen-Ting|Wu, Xin-Lin|Ou, Jian-Ping
PMID: 26332389
Journal: J Exp Clin Cancer Res. 2015 Sep 4;34:94.
Title: Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo.
Author: Xun, Cai|Chen, Min-Bin|Qi, Li|Tie-Ning, Zhang|Peng, Xue|Ning, Li|Zhi-Xiao, Chen|Li-Wei, Wang
PMID: 26337959
Journal: Cell Death Differ. 2015 Oct;22(10):1700-13.
Title: Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer.
Author: Francescangeli, F|Contavalli, P|De Angelis, M L|Baiocchi, M|Gambara, G|Pagliuca, A|Fiorenzano, A|Prezioso, C|Boe, A|Todaro, M|Stassi, G|Castro, N P|Watanabe, K|Salomon, D S|De Maria, R|Minchiotti, G|Zeuner, A
PMID: 26343543
Journal: Mol Med Rep. 2015 Nov;12(5):7169-75.
Title: Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3beta-mediated signal transduction in colon cancer cells.
Author: Yu, Shuyi|Hou, Qian|Sun, Huiping|Liu, Jianping|Li, Jianzhe
PMID: 26352871
Journal: Oncotarget. 2015 Sep 29;6(29):27037-48.
Title: C-kit signaling promotes proliferation and invasion of colorectal mucinous adenocarcinoma in a murine model.
Author: Tan, Jun|Yang, Shu|Shen, Ping|Sun, Haimei|Xiao, Jie|Wang, Yaxi|Wu, Bo|Ji, Fengqing|Yan, Jihong|Xue, Hong|Zhou, Deshan
PMID: 26356816
Journal: Biomed Res Int. 2015;2015:598386.
Title: Lysophosphatidic Acid Inhibits Apoptosis Induced by Cisplatin in Cervical Cancer Cells.
Author: Sui, Yanxia|Yang, Ya|Wang, Ji|Li, Yi|Ma, Hongbing|Cai, Hui|Liu, Xiaoping|Zhang, Yong|Wang, Shufeng|Li, Zongfang|Zhang, Xiaozhi|Wang, Jiansheng|Liu, Rui|Yan, Yanli|Xue, Chaofan|Shi, Xiaowei|Tan, Li|Ren, Juan
PMID: 26366416
Journal: Cancer Med. 2015 Dec;4(12):1798-808.
Title: Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer.
Author: Kaur, Amanpreet|Elzagheid, Adam|Birkman, Eva-Maria|Avoranta, Tuulia|Kytola, Ville|Korkeila, Eija|Syrjanen, Kari|Westermarck, Jukka|Sundstrom, Jari
PMID: 26377365
Journal: Int J Oncol. 2015 Nov;47(5):1767-74.
Title: Toosendanin inhibits growth and induces apoptosis in colorectal cancer cells through suppression of AKT/GSK-3beta/beta-catenin pathway.
Author: Wang, Ge|Feng, Cheng-Cheng|Chu, Shao-Jun|Zhang, Rui|Lu, Yun-Min|Zhu, Jin-Shui|Zhang, Jing
PMID: 26398368
Journal: Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1317-26.
Title: PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.
Author: Chen, Jiezhong|Shao, Renfu|Li, Feng|Monteiro, Michael|Liu, Jun-Ping|Xu, Zhi Ping|Gu, Wenyi
PMID: 26399781
Journal: Int J Mol Sci. 2015 Sep 23;16(9):22976-88.
Title: Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.
Author: Temraz, Sally|Mukherji, Deborah|Shamseddine, Ali
PMID: 26404261
Journal: Metallomics. 2015 Oct;7(10):1390-8.
Title: Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.
Author: Marshall, Kathryn M|Laval, Marie|Estacio, Ortis|Hudson, Damien F|Kalitsis, Paul|Shulkes, Arthur|Baldwin, Graham S|Patel, Oneel
PMID: 26404630
Journal: PLoS One. 2015 Sep 25;10(9):e0139497.
Title: Retraction: MicroRNA-302a Functions as a Putative Tumor Suppressor in Colon Cancer by Targeting Akt.
Author:
PMID: 26407228
Journal: Asian Pac J Cancer Prev. 2015;16(15):6549-56.
Title: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
Author: Wee, Lee Heng|Morad, Noor Azian|Aan, Goon Jo|Makpol, Suzana|Wan Ngah, Wan Zurinah|Mohd Yusof, Yasmin Anum
PMID: 26434873
Journal: Sci Rep. 2015 Oct 8;5:14739.
Title: Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.
Author: Lu, Junyan|Zeng, Hanlin|Liang, Zhongjie|Chen, Limin|Zhang, Liyi|Zhang, Hao|Liu, Hong|Jiang, Hualiang|Shen, Bairong|Huang, Ming|Geng, Meiyu|Spiegel, Sarah|Luo, Cheng
PMID: 26446703
Journal: Oncotarget. 2015 Nov 17;6(36):38667-80.
Title: Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3beta pathway in human colon cancer.
Author: Gao, Fei|Huang, Wei|Zhang, YuQin|Tang, ShaoHui|Zheng, Lin|Ma, Feng|Wang, YiMing|Tang, Hui|Li, Xin
PMID: 26452029
Journal: Curr Cancer Drug Targets. 2015;15(8):703-15.
Title: Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice.
Author: Maurel, Joan|Postigo, Antonio
PMID: 26452385
Journal: Cancer Cell Int. 2015 Oct 9;15:96.
Title: Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy.
Author: Ramasamy, Thamil Selvee|Ayob, Ain Zubaidah|Myint, Hsu Hsu Lynn|Thiagarajah, Sharmanee|Amini, Farahnaz
PMID: 26457069
Journal: Neoplasma. 2015;62(6):855-63.
Title: MicroRNA-219-5p functions as a tumor suppressor partially by targeting platelet-derived growth factor receptor alpha in colorectal cancer.
Author: Xiong, G B|Zhang, G N|Xiao, Y|Niu, B Z|Qiu, H Z|Wu, B|Lin, G L|You, L|Shu, H
PMID: 26458304
Journal: Int J Oncol. 2015 Dec;47(6):2247-54.
Title: Oleanolic acid modulates multiple intracellular targets to inhibit colorectal cancer growth.
Author: Li, Li|Wei, Lihui|Shen, Aling|Chu, Jianfeng|Lin, Jiumao|Peng, Jun
PMID: 26459864
Journal: Oncotarget. 2015 Nov 3;6(34):35991-6002.
Title: Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acry lamide in human colorectal cancer cells in vitro and in vivo.
Author: Chen, Chun-Han|Lee, Chia-Hwa|Liou, Jing-Ping|Teng, Che-Ming|Pan, Shiow-Lin
PMID: 26462017
Journal: Int J Clin Exp Pathol. 2015 Aug 1;8(8):9097-104. eCollection 2015.
Title: The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway.
Author: Zhang, Ling|Zhu, Shengtao|Shi, Xuesen|Sha, Weihong
PMID: 26464652
Journal: PLoS One. 2015 Oct 15;10(10):e0140479.
Title: Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092.
Author: Yu, Yi|Savage, Ronald E|Eathiraj, Sudharshan|Meade, Justin|Wick, Michael J|Hall, Terence|Abbadessa, Giovanni|Schwartz, Brian
PMID: 26469692
Journal: Sci Rep. 2015 Oct 16;5:15239.
Title: Pterostilbine, an active component of blueberries, sensitizes colon cancer cells to 5-fluorouracil cytotoxicity.
Author: Tolba, Mai F|Abdel-Rahman, Sherif Z
PMID: 26472352
Journal: Neoplasia. 2015 Sep;17(9):704-715.
Title: Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.
Author: Bilsland, Alan E|Pugliese, Angelo|Liu, Yu|Revie, John|Burns, Sharon|McCormick, Carol|Cairney, Claire J|Bower, Justin|Drysdale, Martin|Narita, Masashi|Sadaie, Mahito|Keith, W Nicol
PMID: 26476078
Journal: World J Gastrointest Oncol. 2015 Oct 15;7(10):184-203.
Title: Role of retinoids in the prevention and treatment of colorectal cancer.
Author: Applegate, Catherine C|Lane, Michelle A
PMID: 26483874
Journal: Oncotarget. 2015 Dec 22;6(41):43342-62.
Title: Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis.
Author: Vetillard, Alexandra|Jonchere, Barbara|Moreau, Marie|Toutain, Bertrand|Henry, Cecile|Fontanel, Simon|Bernard, Anne-Charlotte|Campone, Mario|Guette, Catherine|Coqueret, Olivier
PMID: 26485768
Journal: Int J Oncol. 2015 Dec;47(6):2226-32.
Title: Sulforaphane inhibits hypoxia-induced HIF-1alpha and VEGF expression and migration of human colon cancer cells.
Author: Kim, Dong Hwan|Sung, Bokyung|Kang, Yong Jung|Hwang, Seong Yeon|Kim, Min Jeong|Yoon, Jeong-Hyun|Im, Eunok|Kim, Nam Deuk
PMID: 26498863
Journal: Oncol Rep. 2015 Dec;34(6):3203-11.
Title: Antiproliferation effect of evodiamine in human colon cancer cells is associated with IGF-1/HIF-1alpha downregulation.
Author: Huang, Jun|Chen, Zhen-Hua|Ren, Chun-Mei|Wang, Dong-Xu|Yuan, Shuang-Xue|Wu, Qiu-Xiang|Chen, Qian-Zhao|Zeng, Yu-Hua|Shao, Ying|Li, Yang|Wu, Ke|Yu, Yu|Sun, Wen-Juan|He, Bai-Cheng
PMID: 26503233
Journal: Am J Chin Med. 2015;43(7):1471-86.
Title: Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway.
Author: Meng, Yan|Lin, Zhao-Min|Ge, Nan|Zhang, Deng-Lu|Huang, Jie|Kong, Feng
PMID: 26503559
Journal: Anticancer Res. 2015 Nov;35(11):5983-91.
Title: Synergistic Effect of SN-38 in Combination with Cetuximab on Angiogenesis and Cancer Cell Invasion.
Author: Pham, Minh Hien|Delestre, Laure|Dewitte, Amelie|Wattez, Nicole|Lepretre, Frederic|Lansiaux, Amelie
PMID: 26504021
Journal: Oncotarget. 2015 Dec 1;6(38):40815-21.
Title: A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations.
Author: Chen, Dawei|Huang, Xuesong|Cai, Jie|Guo, Sheng|Qian, Wubin|Wery, Jean-Pierre|Li, Qi-Xiang
PMID: 26512781
Journal: PLoS One. 2015 Nov 6;10(11):e0141753.
Title: The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the beta-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
Author: Regmi, Sushil C|Park, Su Young|Kim, Seung Joo|Banskota, Suhrid|Shah, Sajita|Kim, Dong-Hee|Kim, Jung-Ae
PMID: 26544726
Journal: PLoS One. 2015 Nov 18;10(11):e0143384.
Title: Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells.
Author: Abdel Hadi, Loubna|Di Vito, Clara|Marfia, Giovanni|Ferraretto, Anita|Tringali, Cristina|Viani, Paola|Riboni, Laura
PMID: 26580959
Journal: PLoS One. 2015 Nov 25;10(11):e0142928.
Title: Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status.
Author: LeJeune, Timothy M|Tsui, Hei Yin|Parsons, Laura B|Miller, Gerald E|Whitted, Crystal|Lynch, Kayla E|Ramsauer, Robert E|Patel, Jasmine U|Wyatt, Jarrett E|Street, Doris S|Adams, Carolyn B|McPherson, Brian|Tsui, Hei Man|Evans, Julie A|Livesay, Christopher|Tor
PMID: 26606169
Journal: Mar Drugs. 2015 Nov 19;13(11):6962-76.
Title: Salternamide A Suppresses Hypoxia-Induced Accumulation of HIF-1alpha and Induces Apoptosis in Human Colorectal Cancer Cells.
Author: Bach, Duc-Hiep|Kim, Seong-Hwan|Hong, Ji-Young|Park, Hyen Joo|Oh, Dong-Chan|Lee, Sang Kook
PMID: 26610526
Journal: Elife. 2015 Nov 27;4.
Title: Greatwall promotes cell transformation by hyperactivating AKT in human malignancies.
Author: Vera, Jorge|Lartigue, Lydia|Vigneron, Suzanne|Gadea, Gilles|Gire, Veronique|Del Rio, Maguy|Soubeyran, Isabelle|Chibon, Frederic|Lorca, Thierry|Castro, Anna
PMID: 26613407
Journal: Cell Adh Migr. 2015;9(6):495-501.
Title: Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail.
Author: Feng, Jutao|Cen, Junhua|Li, Jun|Zhao, Rujin|Zhu, Canhua|Wang, Zongxin|Xie, Jiafen|Tang, Wei
PMID: 26632346
Journal: Cell Rep. 2015 Dec 22;13(11):2440-2455.
Title: The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.
Author: Li, Ning|Yousefi, Maryam|Nakauka-Ddamba, Angela|Li, Fan|Vandivier, Lee|Parada, Kimberly|Woo, Dong-Hun|Wang, Shan|Naqvi, Ammar S|Rao, Shilpa|Tobias, John|Cedeno, Ryan J|Minuesa, Gerard|Y, Katz|Barlowe, Trevor S|Valvezan, Alexander|Shankar, Sheila|Deering,
PMID: 26673327
Journal: BMC Cancer. 2015 Dec 16;15:969.
Title: Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo.
Author: Yang, Shu|Li, Wenshuai|Sun, Haimei|Wu, Bo|Ji, Fengqing|Sun, Tingyi|Chang, Huanhuan|Shen, Ping|Wang, Yaxi|Zhou, Deshan
PMID: 26674205
Journal: PLoS One. 2015 Dec 17;10(12):e0144708.
Title: Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author: Briffa, Romina|Um, Inhwa|Faratian, Dana|Zhou, Ying|Turnbull, Arran K|Langdon, Simon P|Harrison, David J
PMID: 26678268
Journal: Am J Cancer Res. 2015 Sep 15;5(10):3085-97. eCollection 2015.
Title: Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.
Author: Yang, Dong|Wang, Lin-Lin|Dong, Tao-Tao|Shen, Yi-Hang|Guo, Xiao-Sun|Liu, Chuan-Yong|Liu, Jie|Zhang, Pei|Li, Juan|Sun, Yu-Ping
PMID: 26693061
Journal: Biosci Rep. 2015 Dec 24;36(1):e00293.
Title: Interrupted E2F1-miR-34c-SCF negative feedback loop by hyper-methylation promotes colorectal cancer cell proliferation.
Author: Yang, Shu|Wu, Bo|Sun, Haimei|Ji, Fengqing|Sun, Tingyi|Zhao, Yan|Zhou, Deshan
PMID: 26704889
Journal: Int J Mol Sci. 2015 Dec 29;17(1). pii: ijms17010041.
Title: Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
Author: Ren, Bao-Jun|Zhou, Zhi-Wei|Zhu, Da-Jian|Ju, Yong-Le|Wu, Jin-Hao|Ouyang, Man-Zhao|Chen, Xiao-Wu|Zhou, Shu-Feng
PMID: 26729093
Journal: Gastroenterol Res Pract. 2015;2015:457193.
Title: Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways.
Author: Wang, Jie|Chen, Chao|Wang, Shiying|Zhang, Yong|Yin, Peihao|Gao, Zhongxiang|Xu, Jie|Feng, Dianxu|Zuo, Qinsong|Zhao, Ronghua|Chen, Teng
PMID: 26770191
Journal: Oncol Lett. 2015 Dec;10(6):3682-3688.
Title: Functional mechanism of the enhancement of 5-fluorouracil sensitivity by TUSC4 in colon cancer cells.
Author: Liu, Ming-Na|Liu, Ai-Yun|Pei, Feng-Hua|Ma, Xiao|Fan, Yu-Jing|DU, Ya-Ju|Liu, Bing-Rong
PMID: 26788191
Journal: Am J Cancer Res. 2015 Oct 15;5(11):3286-300. eCollection 2015.
Title: Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer.
Author: Park, Young-Lan|Myung, Eun|Park, Sun-Young|Kim, Nuri|Oak, Chan-Young|Myung, Dae-Seong|Cho, Sung-Bum|Lee, Wan-Sik|Kweon, Sun-Seog|Kim, Hyun-Soo|Joo, Young-Eun
PMID: 26807311
Journal: Int J Biochem Cell Biol. 2015 Dec;69:153-61.
Title: The loss of MiR-139-5p promotes colitis-associated tumorigenesis by mediating PI3K/AKT/Wnt signaling.
Author: Maoa, Rurong|Zou, Fangyuan|Yang, Liyan|Lin, Shengchao|Li, Yueqi|Ma, Mingxing|Yin, Peihao|Liang, Xin|Liu, Jianwen
PMID: 27022656
Journal: J Pathol Clin Res. 2014 Nov 5;1(1):3-17.
Title: The molecular background of mucinous carcinoma beyond MUC2.
Author: Hugen, Niek|Simons, Michiel|Halilovic, Altuna|van der Post, Rachel S|Bogers, Anna J|Marijnissen-van Zanten, Monica Aj|de Wilt, Johannes Hw|Nagtegaal, Iris D
PMID: 27499889
Journal: Clin Cancer Drugs. 2015 Feb;2(2):100-111.
Title: Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies.
Author: Johnson, Benny|Mahadevan, Daruka
PMID: 27595061
Journal: Environ Toxicol. 2016 Jan;31(1):77-84.
Title: Hinokitiol induces autophagy in murine breast and colorectal cancer cells.
Author: Wang, Wei-Kuang|Lin, Song-Tao|Chang, Wen-Wei|Liu, Li-Wen|Li, Tom Yu-Tung|Kuo, Chun-Yu|Hsieh, Jeng-Long|Lee, Che-Hsin
PMID: 25044443
Journal: Mol Carcinog. 2016 Mar;55(3):233-44.
Title: PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition.
Author: Al-Qasem, Abeer|Al-Howail, Huda A|Al-Swailem, Mashael|Al-Mazrou, Amer|Al-Otaibi, Basem|Al-Jammaz, Ibrahim|Al-Khalaf, Huda H|Aboussekhra, Abdelilah
PMID: 25641341
Journal: Mol Carcinog. 2016 May;55(5):411-9.
Title: LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET.
Author: Mezquita, Belen|Pineda, Estela|Mezquita, Jovita|Mezquita, Pau|Pau, Montserrat|Codony-Servat, Jordi|Martinez-Balibrea, Eva|Mora, Conchi|Maurel, Joan|Mezquita, Cristobal
PMID: 25647613
Journal: Environ Toxicol. 2016 Aug;31(8):957-69.
Title: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author: Lin, Chin-Chung|Lee, Ming-Huei|Lin, Ju-Hwa|Lin, Meng-Liang|Chueh, Fu-Shin|Yu, Chien-Chih|Lin, Jing-Pin|Chou, Yu-Cheng|Hsu, Shu-Chun|Chung, Jing-Gung
PMID: 25689151
Journal: Eur J Nutr. 2016 Mar;55(2):491-503.
Title: The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer.
Author: Hsuan, Shu-Wen|Chyau, Charng-Cherng|Hung, Hsiao-Yu|Chen, Jing-Hsien|Chou, Fen-Pi
PMID: 25720497
Journal: Mol Carcinog. 2016 May;55(5):514-24.
Title: Microcystin-LR promotes migration and invasion of colorectal cancer through matrix metalloproteinase-13 up-regulation.
Author: Miao, Chen|Ren, Yan|Chen, Meng|Wang, Zhen|Wang, Ting
PMID: 25789966
Journal: Pharm Biol. 2016;54(1):74-9.
Title: Genistein induces activation of the mitochondrial apoptosis pathway by inhibiting phosphorylation of Akt in colorectal cancer cells.
Author: Qin, Jian|Teng, JiaAn|Zhu, Zhou|Chen, JiaXin|Huang, Wen-Jun
PMID: 25880142
Journal: Mol Carcinog. 2016 May;55(5):793-807.
Title: UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients.
Author: Cacciola, Nunzio Antonio|Calabrese, Chiara|Malapelle, Umberto|Pellino, Gianluca|De Stefano, Alfonso|Sepe, Romina|Sgariglia, Roberta|Quintavalle, Cristina|Federico, Antonella|Bianco, Antonio|Uchimura Bastos, Andre|Milone, Marco|Bellevicine, Claudio|Milone,
PMID: 25917796
Journal: Gut. 2016 Jul;65(7):1151-64.
Title: BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.
Author: Urban, Bettina C|Collard, Tracey J|Eagle, Catherine J|Southern, Samantha L|Greenhough, Alexander|Hamdollah-Zadeh, Maryam|Ghosh, Anil|Poulsom, Richard|Paraskeva, Christos|Silver, Andrew|Williams, Ann C
PMID: 26033966
Journal: J Cancer Res Clin Oncol. 2016 Jan;142(1):59-72.
Title: Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.
Author: Chang, Ligong|Wu, Peng|Senthilkumar, Ravichandran|Tian, Xiaoqiang|Liu, Hui|Shen, Xia|Tao, Zijian|Huang, Peilin
PMID: 26109148
Journal: J Cell Physiol. 2016 Feb;231(2):459-72.
Title: Selective beta2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis.
Author: Chin, Chih-Chien|Li, Jhy-Ming|Lee, Kam-Fai|Huang, Yun-Ching|Wang, Kuan-Chieh|Lai, Hsiao-Ching|Cheng, Chih-Chung|Kuo, Yi-Hung|Shi, Chung-Sheng
PMID: 26189563
Journal: J Cell Biochem. 2016 Feb;117(2):458-69.
Title: PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells.
Author: de Araujo, Wallace Martins|Robbs, Bruno Kaufmann|Bastos, Lilian G|de Souza, Waldemir F|Vidal, Flavia C B|Viola, Joao P B|Morgado-Diaz, Jose A
PMID: 26224641
Journal: Clin Cancer Res. 2016 Feb 1;22(3):644-56.
Title: Tankyrase Inhibition Blocks Wnt/beta-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
Author: Arques, Oriol|Chicote, Irene|Puig, Isabel|Tenbaum, Stephan P|Argiles, Guillem|Dienstmann, Rodrigo|Fernandez, Natalia|Caratu, Ginevra|Matito, Judit|Silberschmidt, Daniel|Rodon, Jordi|Landolfi, Stefania|Prat, Aleix|Espin, Eloy|Charco, Ramon|Nuciforo, Paolo|
PMID: 26224873
Journal: J Gastroenterol Hepatol. 2016 Jan;31(1):256-64.
Title: Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Author: Wubetu, Gizachew Y|Shimada, Mitsuo|Morine, Yuji|Ikemoto, Tetsuya|Ishikawa, Daichi|Iwahashi, Shuichi|Yamada, Shinichiro|Saito, Yu|Arakawa, Yusuke|Imura, Satoru
PMID: 26241688
Journal: Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38.
Title: RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
Author: Fang, Bingliang
PMID: 26350096
Journal: Tumour Biol. 2016 Feb;37(2):2353-63.
Title: Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Author: Xiao, Ming|Tang, Yi|Chen, Wen-Wen|Wang, Ya-Lan|Yang, Lian|Li, Xian|Song, Guang-Lin|Kuang, Jing
PMID: 26373733
Journal: Tumour Biol. 2016 Feb;37(2):2519-26.
Title: Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.
Author: Tveteraas, Ingun Heiene|Aasrum, Monica|Brusevold, Ingvild Johnsen|Odegard, John|Christoffersen, Thoralf|Sandnes, Dagny
PMID: 26386720
Journal: Oncogene. 2016 Jun 9;35(23):3049-61.
Title: INPP4B is an oncogenic regulator in human colon cancer.
Author: Guo, S T|Chi, M N|Yang, R H|Guo, X Y|Zan, L K|Wang, C Y|Xi, Y F|Jin, L|Croft, A|Tseng, H-Y|Yan, X G|Farrelly, M|Wang, F H|Lai, F|Wang, J F|Li, Y P|Ackland, S|Scott, R|Agoulnik, I U|Hondermarck, H|Thorne, R F|Liu, T|Zhang, X D|Jiang, C C
PMID: 26411369
Journal: J Cell Physiol. 2016 May;231(5):1097-105.
Title: Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells.
Author: Mirone, Giovanna|Perna, Stefania|Shukla, Arvind|Marfe, Gabriella
PMID: 26419617
Journal: Int J Cancer. 2016 Mar 15;138(6):1516-27.
Title: Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status.
Author: Kato, Junko|Futamura, Manabu|Kanematsu, Masako|Gaowa, Siqin|Mori, Ryutaro|Tanahashi, Toshiyuki|Matsuhashi, Nobuhisa|Yoshida, Kazuhiro
PMID: 26437179
Journal: Oncogene. 2016 Jun 9;35(23):2991-3003.
Title: SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.
Author: Barbachano, A|Fernandez-Barral, A|Pereira, F|Segura, M F|Ordonez-Moran, P|Carrillo-de Santa Pau, E|Gonzalez-Sancho, J M|Hanniford, D|Martinez, N|Costales-Carrera, A|Real, F X|Palmer, H G|Rojas, J M|Hernando, E|Munoz, A
PMID: 26455323
Journal: Ann Surg Oncol. 2016 Mar;23(3):849-55.
Title: Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Author: Chang, Shih-Ching|Lin, Pei-Ching|Lin, Jen-Kou|Lin, Chien-Hsing|Yang, Shung-Haur|Liang, Wen-Yi|Chen, Wei-Shone|Jiang, Jeng-Kai
PMID: 26471487
Journal: Mol Nutr Food Res. 2016 Feb;60(2):242-55.
Title: Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice.
Author: Giner, Elisa|Recio, M Carmen|Rios, Jose Luis|Cerda-Nicolas, Jose Miguel|Giner, Rosa Maria
PMID: 26502315
Journal: Oncotarget. 2016 Jan 12;7(2):1311-22.
Title: NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.
Author: Zheng, Jianyong|Li, Yunming|Zhu, Shaojun|Li, Jipeng|Zhao, Qingchuan|Ji, Gang|Wang, Weizhong|Chu, Dake
PMID: 26515606
Journal: Oncol Rep. 2016 Jan;35(1):205-10.
Title: Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway.
Author: Xiang, Tao|Fei, Rushan|Wang, Zhe|Shen, Zhonglei|Qian, Jing|Chen, Wenbin
PMID: 26530054
Journal: Exp Neurol. 2016 Jan;275 Pt 1:11-6.
Title: Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion.
Author: Jiang, Shu-Ping|Zhang, Zhen-Dong|Kang, Lu-Mei|Wang, Qing-Hua|Zhang, Lei|Chen, Hong-Ping
PMID: 26546510
Journal: Int J Biochem Cell Biol. 2016 Jan;70:29-38.
Title: Arginine deprivation induces endoplasmic reticulum stress in human solid cancer cells.
Author: Bobak, Yaroslav|Kurlishchuk, Yuliya|Vynnytska-Myronovska, Bozhena|Grydzuk, Olesia|Shuvayeva, Galyna|Redowicz, Maria J|Kunz-Schughart, Leoni A|Stasyk, Oleh
PMID: 26546743
Journal: Oncotarget. 2016 Jan 5;7(1):798-813.
Title: Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive niche.
Author: Xu, Xiaowen|Chang, Wenjun|Yuan, Jie|Han, Xue|Tan, Xiaojie|Ding, Yibo|Luo, Yanxin|Cai, Hui|Liu, Yan|Gao, Xianhua|Liu, Qizhi|Yu, Yongwei|Du, Yan|Wang, Hao|Ma, Liye|Wang, Jianping|Chen, Kun|Ding, Yanqing|Fu, Chuangang|Cao, Guangwen
PMID: 26556874
Journal: Tumour Biol. 2016 May;37(5):6155-68.
Title: Inhibition of phospholipaseD2 increases hypoxia-induced human colon cancer cell apoptosis through inactivating of the PI3K/AKT signaling pathway.
Author: Liu, Maoxi|Fu, Zhongxue|Wu, Xingye|Du, Kunli|Zhang, Shouru|Zeng, Li
PMID: 26614430
Journal: Food Chem Toxicol. 2016 Jan;87:1-11.
Title: A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells.
Author: Wani, Zahoor Ahmad|Guru, Santosh Kumar|Rao, A V Subba|Sharma, Sonia|Mahajan, Girish|Behl, Akanksha|Kumar, Ashok|Sharma, P R|Kamal, Ahmed|Bhushan, Shashi|Mondhe, Dilip M
PMID: 26615871
Journal: Tumour Biol. 2016 May;37(5):6389-402.
Title: Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma.
Author: Pal, Ipsita|Dey, Kaushik Kumar|Chaurasia, Madhuri|Parida, Sheetal|Das, Subhayan|Rajesh, Y|Sharma, Kulbhushan|Chowdhury, Tamohan|Mandal, Mahitosh
PMID: 26631035
Journal: Cancer Res. 2016 Feb 1;76(3):607-18.
Title: SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness.
Author: Crottes, David|Rapetti-Mauss, Raphael|Alcaraz-Perez, Francisca|Tichet, Melanie|Gariano, Giuseppina|Martial, Sonia|Guizouarn, Helene|Pellissier, Bernard|Loubat, Agnes|Popa, Alexandra|Paquet, Agnes|Presta, Marco|Tartare-Deckert, Sophie|Cayuela, Maria Luisa|
PMID: 26645564
Journal: Oncotarget. 2016 Jan 26;7(4):3921-33.
Title: Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk.
Author: Ye, Ying|Xiao, Ling|Wang, Su-Juan|Yue, Wei|Yin, Qiao-Shan|Sun, Meng-Yao|Xia, Wei|Shao, Zhi-Yi|Zhang, Hong
PMID: 26646797
Journal: Oncol Rep. 2016 Mar;35(3):1807-15.
Title: Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade.
Author: Zhang, Binhao|Leng, Chao|Wu, Chao|Zhang, Zhanguo|Dou, Lei|Luo, Xin|Zhang, Bixiang|Chen, Xiaoping
PMID: 26647806
Journal: Int Immunopharmacol. 2016 Jan;30:57-61.
Title: Enhancement of CD3AK cell proliferation and killing ability by alpha-Thujone.
Author: Zhou, Yu|Liu, Jun-Quan|Zhou, Zhong-Hai|Lv, Xiao-Ting|Chen, Yong-Qiang|Sun, Lei-Qing|Chen, Fu-Xing
PMID: 26655741
Journal: Cancer Res. 2016 Jan 1;76(1):83-95.
Title: Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis.
Author: Xing, Cheng|Lu, Xing-Xing|Guo, Peng-Da|Shen, Tong|Zhang, Shen|He, Xiao-Shun|Gan, Wen-Juan|Li, Xiu-Ming|Wang, Jing-Ru|Zhao, Yuan-Yuan|Wu, Hua|Li, Jian-Ming
PMID: 26669864
Journal: Food Funct. 2016 Feb;7(2):843-54.
Title: A serine protease extracted from Trichosanthes kirilowii induces apoptosis via the PI3K/AKT-mediated mitochondrial pathway in human colorectal adenocarcinoma cells.
Author: Song, Li|Chang, Jiao|Li, Zhuoyu
PMID: 26673746
Journal: Oncol Rep. 2016 Mar;35(3):1501-10.
Title: Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway.
Author: Li, Jiepin|Teng, Yuhao|Liu, Shenlin|Wang, Zifan|Chen, Yan|Zhang, Yingying|Xi, Songyang|Xu, Song|Wang, Ruiping|Zou, Xi
PMID: 26677144
Journal: J Enzyme Inhib Med Chem. 2016 Dec;31(6):1286-99.
Title: Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells.
Author: Malki, Ahmed|Ashour, Hayam M A|Elbayaa, Rasha Y|Issa, Doaa A E|Aziz, Hassan A|Chen, Xiaozhuo
PMID: 26677729
Journal: Oncotarget. 2016 Jan 26;7(4):4542-58.
Title: The B56gamma3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.
Author: Lai, Tai-Yu|Yen, Chia-Jui|Tsai, Hung-Wen|Yang, Yu-San|Hong, Wei-Fu|Chiang, Chi-Wu
PMID: 26684356
Journal: J Pathol. 2016 Mar;238(4):562-70.
Title: HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Author: Richman, Susan D|Southward, Katie|Chambers, Philip|Cross, Debra|Barrett, Jennifer|Hemmings, Gemma|Taylor, Morag|Wood, Henry|Hutchins, Gordon|Foster, Joseph M|Oumie, Assa|Spink, Karen G|Brown, Sarah R|Jones, Marc|Kerr, David|Handley, Kelly|Gray, Richard|Se
PMID: 26690310
Journal: Cancer Res Treat. 2016 Jul;48(3):1141-53.
Title: Dexamethasone Inhibits TGF-beta1-Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61.
Author: Han, Sanghoon|Bui, Ngoc Thuy|Ho, Manh Tin|Kim, Young Mee|Cho, Moonjae|Shin, Dong Bok
PMID: 26693911
Journal: Dig Dis Sci. 2016 Apr;61(4):1091-7.
Title: AKT and JNK Signaling Pathways Increase the Metastatic Potential of Colorectal Cancer Cells by Altering Transgelin Expression.
Author: Zhou, Huimin|Zhang, Yiming|Chen, Qikui|Lin, Ying
PMID: 26694173
Journal: Oncol Rep. 2016 Feb;35(2):1091-100.
Title: Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
Author: Yousef, Bashir A|Guerram, Mounia|Hassan, Hozeifa M|Hamdi, Aida M|Zhang, Lu-Yong|Jiang, Zhen-Zhou
PMID: 26718323
Journal: Oncol Rep. 2016 Feb;35(2):1075-82.
Title: MiR-331-3p inhibits proliferation and promotes apoptosis by targeting HER2 through the PI3K/Akt and ERK1/2 pathways in colorectal cancer.
Author: Zhao, Dongli|Sui, Yanxia|Zheng, Xiaoqiang
PMID: 26718987
Journal: Oncol Rep. 2016 Feb;35(2):999-1005.
Title: CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling.
Author: Xiang, Tao|Yu, Feng|Fei, Rushan|Qian, Jing|Chen, Wenbin
PMID: 26719016
Journal: Tumour Biol. 2016 Jun;37(6):8413-23.
Title: Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer.
Author: Jiao, Lin|Li, Dan-Dan|Yang, Chen-Lu|Peng, Rui-Qing|Guo, Yi-Qun|Zhang, Xiao-Shi|Zhu, Xiao-Feng
PMID: 26733168
Journal: Biosci Rep. 2016 Jan 6;36(1):e00299.
Title: The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression.
Author: Ho, Nelson|Morrison, Jodi|Silva, Andreza|Coomber, Brenda L
PMID: 26740252
Journal: Oncotarget. 2016 Feb 23;7(8):8823-38.
Title: Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Author: Wang, Xiao-Qing|Tang, Zu-Xiong|Yu, Dong|Cui, Shu-Jian|Jiang, Ying-Hua|Zhang, Qian|Wang, Jie|Yang, Peng-Yuan|Liu, Feng
PMID: 26741506
Journal: J Transl Med. 2016 Jan 8;14:6.
Title: Nanoproteomic analysis of ischemia-dependent changes in signaling protein phosphorylation in colorectal normal and cancer tissue.
Author: Unger, Florian T|Lange, Nicole|Kruger, Jana|Compton, Carolyn|Moore, Helen|Agrawal, Lokesh|Juhl, Hartmut|David, Kerstin A
PMID: 26742633
Journal: Tumour Biol. 2016 Jul;37(7):8811-24.
Title: Upregulation of CD44v6 contributes to acquired chemoresistance via the modulation of autophagy in colon cancer SW480 cells.
Author: Lv, Lin|Liu, Hai-Guang|Dong, Si-Yang|Yang, Fan|Wang, Qing-Xuan|Guo, Gui-Long|Pan, Yi-Fei|Zhang, Xiao-Hua
PMID: 26747179
Journal: Oncol Rep. 2016 Mar;35(3):1403-8.
Title: Expression and mechanism of microRNA-181A on incidence and survival in late liver metastases of colorectal cancer.
Author: Li, Zengjun|Wang, Haipeng|Xu, Zhongfa|Sun, Yanlai|Han, Jianjun
PMID: 26750720
Journal: Mol Carcinog. 2016 Dec;55(12):2135-2155.
Title: A novel PI3K axis selective molecule exhibits potent tumor inhibition in colorectal carcinogenesis.
Author: Hussain, Aashiq|Qazi, Asif Khurshid|Mupparapu, Nagaraju|Kumar, Ashok|Mintoo, Mubashir Javeed|Mahajan, Girish|Sharma, Parduman Raj|Singh, Shashank Kumar|Bharate, Sandip B|Zargar, Mohmmad Afzal|Ahmed, Qazi Naveed|Mondhe, Dilip Manikrao|Vishwakarma, Ram A|Ha
PMID: 26764221
Journal: Mol Carcinog. 2016 Dec;55(12):2196-2209.
Title: The PI3K/Akt pathway is involved in procyanidin-mediated suppression of human colorectal cancer cell growth.
Author: Choy, Ying Yng|Fraga, Magdalena|Mackenzie, Gerardo G|Waterhouse, Andrew L|Cremonini, Eleonora|Oteiza, Patricia I
PMID: 26774105
Journal: Neoplasma. 2016;63(2):193-200.
Title: Chidamide and 5-flurouracil show a synergistic antitumor effect on human colon cancer xenografts in nude mice.
Author: Liu, L|Qiu, S|Liu, Y|Liu, Z|Zheng, Y|Su, X|Chen, B|Chen, H
PMID: 26774139
Journal: Future Oncol. 2016 Feb;12(4):515-24.
Title: Effective targeting of colorectal cancer cells using TORC1/2 kinase inhibitors in vitro and in vivo.
Author: Zhang, Jie|Jiang, Wen|Liu, Wei|Wu, Juan-Juan|Song, Lei|Cheng, Ji-Xian|Yao, Ming|Yang, Li-Ping|Yao, Deng-Fu
PMID: 26776341
Journal: Tumour Biol. 2016 Jul;37(7):9465-72.
Title: B7-H3 increases thymidylate synthase expression via the PI3k-Akt pathway.
Author: Jiang, Bo|Liu, Fen|Liu, ZhiHui|Zhang, Ting|Hua, Dong
PMID: 26787540
Journal: Dig Dis Sci. 2016 Jun;61(6):1553-60.
Title: Orai1, a Direct Target of microRNA-519, Promotes Progression of Colorectal Cancer via Akt/GSK3beta Signaling Pathway.
Author: Deng, Wei|Wang, Jin|Zhang, Jun|Cai, Jun|Bai, Zhigang|Zhang, Zhongtao
PMID: 26792278
Journal: Biochem Biophys Res Commun. 2016 Feb 5;470(2):397-404.
Title: Rab11-FIP2 promotes colorectal cancer migration and invasion by regulating PI3K/AKT/MMP7 signaling pathway.
Author: Xu, Chang-Long|Wang, Jian-Zhang|Xia, Xuan-Ping|Pan, Chen-Wei|Shao, Xiao-Xiao|Xia, Sheng-Long|Yang, Shou-Xing|Zheng, Bo
PMID: 26792722
Journal: J Clin Pathol. 2016 Sep;69(9):767-71.
Title: Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author: Malapelle, Umberto|Pisapia, Pasquale|Sgariglia, Roberta|Vigliar, Elena|Biglietto, Maria|Carlomagno, Chiara|Giuffre, Giuseppe|Bellevicine, Claudio|Troncone, Giancarlo
PMID: 26797410
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Jan;19(1):22-6.
Title: [Application of molecular diagnostic techniques in precision medicine of personalized treatment for colorectal cancer].
Author: Fu, Ji|Lin, Guole
PMID: 26797832
Journal: J Transl Med. 2016 Jan 22;14:21.
Title: Obesity and colorectal cancer: molecular features of adipose tissue.
Author: Martinez-Useros, Javier|Garcia-Foncillas, Jesus
PMID: 26801617
Journal: Oncotarget. 2016 Feb 23;7(8):9188-221.
Title: BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author: Goulielmaki, Maria|Koustas, Evangelos|Moysidou, Eirini|Vlassi, Margarita|Sasazuki, Takehiko|Shirasawa, Senji|Zografos, George|Oikonomou, Eftychia|Pintzas, Alexander
PMID: 26802026
Journal: Cancer Lett. 2016 Mar 28;372(2):226-38.
Title: SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIgamma/AKT-mediated pathway.
Author: Jing, Zhao|Sui, Xinbing|Yao, Junlin|Xie, Jiansheng|Jiang, Liming|Zhou, Yubin|Pan, Hongming|Han, Weidong
PMID: 26803057
Journal: Tumour Biol. 2016 Aug;37(8):10257-67.
Title: Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells.
Author: Zhijun, Huang|Shusheng, Wang|Han, Min|Jianping, Li|Li-Sen, Qin|Dechun, Li
PMID: 26831668
Journal: Molecules. 2016 Jan 30;21(2):169.
Title: Chemopreventive and Therapeutic Effects of Edible Berries: A Focus on Colon Cancer Prevention and Treatment.
Author: Afrin, Sadia|Giampieri, Francesca|Gasparrini, Massimiliano|Forbes-Hernandez, Tamara Y|Varela-Lopez, Alfonso|Quiles, Jose L|Mezzetti, Bruno|Battino, Maurizio
PMID: 26840292
Journal: Int J Oncol. 2016 Apr;48(4):1391-8.
Title: Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-kappaB signal pathway.
Author: Chen, Shaoqin|Chen, Wei|Zhang, Xiang|Lin, Suyong|Chen, Zhihua
PMID: 26847533
Journal: Int J Mol Med. 2016 Mar;37(3):734-42.
Title: Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.
Author: Yang, Lian|Xiao, Ming|Li, Xian|Tang, Yi|Wang, Ya-Lan
PMID: 26847718
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Oncol Lett. 2016 Jan;11(1):685-688.
Title: Baicalein inhibits the migration and invasion of colorectal cancer cells via suppression of the AKT signaling pathway.
Author: Rui, Xiaojiang|Yan, X I|Zhang, Kai
PMID: 26870267
Journal: Eur J Pharmacol. 2016 Apr 5;776:124-31.
Title: Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways.
Author: Lien, Gi-Shih|Lin, Chien-Huang|Yang, You-Lan|Wu, Ming-Shun|Chen, Bing-Chang
PMID: 26879868
Journal: Oncotarget. 2016 Mar 22;7(12):13854-64.
Title: Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.
Author: Suman, Suman|Das, Trinath P|Sirimulla, Suman|Alatassi, Houda|Ankem, Murali K|Damodaran, Chendil
PMID: 26883103
Journal: Oncol Lett. 2016 Feb;11(2):1549-1554.
Title: Downregulation of Foxc2 enhances apoptosis induced by 5-fluorouracil through activation of MAPK and AKT pathways in colorectal cancer.
Author: Yang, Chao|Cui, Xiaoxian|Dai, Xiaoqin|Liao, Wenting
PMID: 26893778
Journal: Chem Biol Interact. 2016 Apr 5;249:23-35.
Title: In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition.
Author: Balachandran, C|Emi, N|Arun, Y|Yamamoto, N|Duraipandiyan, V|Inaguma, Yoko|Okamoto, Akinao|Ignacimuthu, S|Al-Dhabi, N A|Perumal, P T
PMID: 26915975
Journal: Oncotarget. 2016 Mar 29;7(13):16349-61.
Title: AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
Author: Gao, Mei|Kong, Qingbin|Hua, Hui|Yin, Yancun|Wang, Jiao|Luo, Ting|Jiang, Yangfu
PMID: 26918349
Journal: Asian Pac J Cancer Prev. 2016;17(2):743-8.
Title: Impact of Cellular Genetic Make-up on Colorectal Cancer Cell Lines Response to Ellagic Acid: Implications of Small Interfering RNA.
Author: Yousef, Amany I|El-Masry, Omar S|Abdel Mohsen, Mohamed A
PMID: 26925673
Journal: Neoplasma. 2016;63(3):351-61.
Title: Physcion 8-O-beta-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN.
Author: Ding, Z|Xu, F|Tang, J|Li, G|Jiang, P|Tang, Z|Wu, H
PMID: 26925795
Journal: Phytother Res. 2016 Jun;30(6):963-70.
Title: Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-alpha-Dependent Inhibition of Akt/mTOR Pathway.
Author: Sarnelli, Giovanni|Gigli, Stefano|Capoccia, Elena|Iuvone, Teresa|Cirillo, Carla|Seguella, Luisa|Nobile, Nicola|D'Alessandro, Alessandra|Pesce, Marcella|Steardo, Luca|Cuomo, Rosario|Esposito, Giuseppe
PMID: 26929026
Journal: Oncotarget. 2016 Apr 12;7(15):20368-80.
Title: Antitumor effects of calgranulin B internalized in human colon cancer cells.
Author: Kim, Kun|Kim, Kyung-Hee|Roh, Kangsan|Yoo, Byong Chul|Ku, Ja-Lok|Shin, Young-Kyoung|Cho, Jae Youl|Kim, Minjae|Kwon, Myung-Hee|Goh, Sung Ho|Chang, Hee Jin|Oh, Jae Hwan
PMID: 26933915
Journal: Mol Med Rep. 2016 Apr;13(4):3243-8.
Title: Silybin suppresses cell proliferation and induces apoptosis of multiple myeloma cells via the PI3K/Akt/mTOR signaling pathway.
Author: Feng, Nan|Luo, Jianmin|Guo, Ximin
PMID: 26936429
Journal: Arch Biochem Biophys. 2016 Apr 15;596:84-98.
Title: CHNQ, a novel 2-Chloro-1,4-naphthoquinone derivative of quercetin, induces oxidative stress and autophagy both in vitro and in vivo.
Author: Enayat, Shabnam|Seyma Ceyhan, M|Taskoparan, Betul|Stefek, Milan|Banerjee, Sreeparna
PMID: 26946942
Journal: Cancer Lett. 2016 Jun 1;375(2):209-220.
Title: Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development.
Author: Ren, Weiguo|Shen, Shourong|Sun, Zhenqiang|Shu, Peng|Shen, Xiaohua|Bu, Chibin|Ai, Feiyan|Zhang, Xuemei|Tang, Anliu|Tian, Li|Li, Guiyuan|Li, Xiayu|Ma, Jian
PMID: 26965998
Journal: Proteomics. 2016 May;16(10):1557-69.
Title: Mechanistic study of the anti-cancer effect of Gynostemma pentaphyllum saponins in the Apc(Min/+) mouse model.
Author: Tai, William Chi-Shing|Wong, Wing-Yan|Lee, Magnolia Muk-Lan|Chan, Brandon Dow|Lu, Cheng|Hsiao, Wen-Luan Wendy
PMID: 26970558
Journal: Oncogene. 2016 Oct 6;35(40):5237-5247.
Title: Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice.
Author: Liu, W|Li, H|Hong, S-H|Piszczek, G P|Chen, W|Rodgers, G P
PMID: 26973250
Journal: J Gastroenterol. 2016 Oct;51(10):971-84.
Title: Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications.
Author: Belharazem, Djeda|Magdeburg, Julia|Berton, Ann-Kristin|Beissbarth, Li|Sauer, Christian|Sticht, Carsten|Marx, Alexander|Hofheinz, Ralf|Post, Stefan|Kienle, Peter|Strobel, Philipp
PMID: 26984550
Journal: Cancer Res. 2016 May 15;76(10):3014-24.
Title: Intracrine VEGF Signaling Mediates the Activity of Prosurvival Pathways in Human Colorectal Cancer Cells.
Author: Bhattacharya, Rajat|Ye, Xiang-Cang|Wang, Rui|Ling, Xia|McManus, Madonna|Fan, Fan|Boulbes, Delphine|Ellis, Lee M
PMID: 26988990
Journal: Oncotarget. 2016 Apr 12;7(15):20919-33.
Title: Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival.
Author: Dowling, Catriona M|Phelan, James|Callender, Julia A|Cathcart, Mary Clare|Mehigan, Brian|McCormick, Paul|Dalton, Tara|Coffey, John C|Newton, Alexandra C|O'Sullivan, Jacintha|Kiely, Patrick A
PMID: 26989024
Journal: Gene. 2016 Jun 10;584(1):90-6.
Title: Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells.
Author: Sun, Shangfeng|Cheng, Shuguang|Zhu, Yunxiao|Zhang, Peng|Liu, Ning|Xu, Tong|Sun, Chao|Lv, Yanfeng
PMID: 26992638
Journal: Oncol Rep. 2016 Jun;35(6):3363-70.
Title: Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways.
Author: Liu, Jiming|Li, Qiang|Liu, Zhilong|Lin, Liuming|Zhang, Xiangqiang|Cao, Mingrong|Jiang, Jianwei
PMID: 27004568
Journal: Oncotarget. 2016 Apr 19;7(16):22687-99.
Title: DDX3 enhances oncogenic KRASinduced tumor invasion in colorectal cancer via the betacatenin/ZEB1 axis.
Author: Wu, De-Wei|Lin, Po-Lin|Cheng, Ya-Wen|Huang, Chi-Chou|Wang, Lee|Lee, Huei
PMID: 27007150
Journal: Tumour Biol. 2016 Sep;37(9):11743-11752.
Title: Autophagy inhibition sensitizes WYE-354-induced anti-colon cancer activity in vitro and in vivo.
Author: Wang, Lijun|Zhu, Yun-Rong|Wang, Shaowei|Zhao, Song
PMID: 27020593
Journal: Clin Cancer Res. 2016 Jun 1;22(11):2659-67.
Title: Phase I Study of an AKT Inhibitor (MK-2206) Combined with Lapatinib in Adult Solid Tumors Followed by Dose Expansion in Advanced HER2+ Breast Cancer.
Author: Wisinski, Kari B|Tevaarwerk, Amye J|Burkard, Mark E|Rampurwala, Murtuza|Eickhoff, Jens|Bell, Maria C|Kolesar, Jill M|Flynn, Christopher|Liu, Glenn
PMID: 27026198
Journal: Mol Nutr Food Res. 2016 Sep;60(9):1912-23.
Title: Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.
Author: Kim, Hyemee|Banerjee, Nivedita|Ivanov, Ivan|Pfent, Catherine M|Prudhomme, Kalan R|Bisson, William H|Dashwood, Roderick H|Talcott, Stephen T|Mertens-Talcott, Susanne U
PMID: 27028006
Journal: Mol Biol (Mosk). 2016 Jan-Feb;50(1):174-8.
Title: [Alpha-1 Antitrypsin Affects U0126-Induced Cytotoxicity in Colon Cancer Cell Line (HCT116)].
Author: Ljujic, M|Mijatovic, S|Bulatovic, M Z|Mojic, M|Maksimovic-Ivanic, D|Radojkovic, D|Topic, A
PMID: 27028823
Journal: Free Radic Biol Med. 2016 Jun;95:121-32.
Title: Cytoplasmic localization of Nrf2 promotes colorectal cancer with more aggressive tumors via upregulation of PSMD4.
Author: Lin, Po-Lin|Chang, Jinghua Tsai|Wu, De-Wei|Huang, Chi-Chou|Lee, Huei
PMID: 27033953
Journal: Genes Chromosomes Cancer. 2016 Jul;55(7):577-90.
Title: Lentivirus-mediated somatic recombination and development of a novel mouse model for sporadic colorectal cancer.
Author: Vaish, Vivek|Kim, Joohwee|Shim, Minsub
PMID: 27037682
Journal: Biomed Pharmacother. 2016 Apr;79:112-9.
Title: Pristimerin inhibits proliferation, migration and invasion, and induces apoptosis in HCT-116 colorectal cancer cells.
Author: Yousef, Bashir A|Hassan, Hozeifa M|Guerram, Mounia|Hamdi, Aida M|Wang, Bin|Zhang, Lu-Yong|Jiang, Zhen-Zhou
PMID: 27044819
Journal: Int J Biochem Cell Biol. 2016 Jun;75:53-62.
Title: High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer.
Author: Luo, Yang|Ye, Guang-Yao|Qin, Shao-Lan|Mu, Yi-Fei|Zhang, Lei|Qi, Yang|Qiu, Yi-Er|Yu, Min-Hao|Zhong, Ming
PMID: 27046094
Journal: Oncotarget. 2016 May 3;7(18):26780-92.
Title: Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer.
Author: Bao, Yonghua|Li, Kai|Guo, Yongchen|Wang, Qian|Li, Zexin|Yang, Yiqiong|Chen, Zhiguo|Wang, Jianguo|Zhao, Weixing|Zhang, Huijuan|Chen, Jiwang|Dong, Huali|Shen, Kui|Diamond, Alan M|Yang, Wancai
PMID: 27050145
Journal: J Cancer Prev. 2016 Mar;21(1):26-31.
Title: Dehydroglyasperin D Inhibits the Proliferation of HT-29 Human Colorectal Cancer Cells Through Direct Interaction With Phosphatidylinositol 3-kinase.
Author: Jung, Sung Keun|Jeong, Chul-Ho
PMID: 27051646
Journal: Front Med. 2016 Jun;10(2):178-82.
Title: Bioinformatic exploration of MTA1-regulated gene networks in colon cancer.
Author: Li, Chunxiao|Wang, Haijuan|Lin, Feng|Li, Hui|Wen, Tao|Qian, Haili|Zhan, Qimin
PMID: 27052252
Journal: Oxid Med Cell Longev. 2016;2016:5874127.
Title: CCL21 Facilitates Chemoresistance and Cancer Stem Cell-Like Properties of Colorectal Cancer Cells through AKT/GSK-3beta/Snail Signals.
Author: Lu, Lin-Lin|Chen, Xiao-Hui|Zhang, Ge|Liu, Zong-Cai|Wu, Nong|Wang, Hao|Qi, Yi-Fei|Wang, Hong-Sheng|Cai, Shao Hui|Du, Jun
PMID: 27057280
Journal: Oncotarget. 2016 May 31;7(22):32306-17.
Title: Visfatin is involved in promotion of colorectal carcinoma malignancy through an inducing EMT mechanism.
Author: Yang, Jing|Zhang, Kun|Song, Haixing|Wu, Mingbo|Li, Jingyi|Yong, Ziyi|Jiang, Sheng|Kuang, Xi|Zhang, Tao
PMID: 27058759
Journal: Ann Surg Oncol. 2016 Sep;23(9):2849-57.
Title: Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.
Author: Malkomes, Patrizia|Lunger, Ilaria|Luetticke, Alexander|Oppermann, Elsie|Haetscher, Nadine|Serve, Hubert|Holzer, Katharina|Bechstein, Wolf Otto|Rieger, Michael A
PMID: 27059026
Journal: J Nat Prod. 2016 Apr 22;79(4):1097-104.
Title: Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
Author: Kim, Won Kyung|Pyee, Yuna|Chung, Hwa-Jin|Park, Hyen Joo|Hong, Ji-Young|Son, Kun Ho|Lee, Sang Kook
PMID: 27064730
Journal: Anticancer Res. 2016 Apr;36(4):1631-9.
Title: NFkappaB-Associated Pathways in Progression of Chemoresistance to 5-Fluorouracil in an In Vitro Model of Colonic Carcinoma.
Author: Korber, Maria Isabel|Staribacher, Anna|Ratzenbock, Ina|Steger, Gunther|Mader, Robert M
PMID: 27069140
Journal: J Pathol. 2016 May;239(1):60-71.
Title: TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/beta-catenin and MAPK signalling.
Author: Gu, Ye|Wang, Qian|Guo, Kang|Qin, Weizhao|Liao, Wenting|Wang, Shuang|Ding, Yanqing|Lin, Jie
PMID: 27071482
Journal: Mol Med Rep. 2016 Jun;13(6):4681-8.
Title: Apoptotic effects of extract from Cnidium monnieri (L.) Cusson by adenosine monosphosphate-activated protein kinase-independent pathway in HCT116 colon cancer cells.
Author: Lim, Eun Gyeong|Kim, Guen Tae|Lee, Se Hee|Kim, Sang-Yong|Kim, Young Min
PMID: 27082059
Journal: Metabolism. 2016 May;65(5):685-98.
Title: Aerobic and resistance training dependent skeletal muscle plasticity in the colon-26 murine model of cancer cachexia.
Author: Khamoui, Andy V|Park, Bong-Sup|Kim, Do-Houn|Yeh, Ming-Chia|Oh, Seung-Lyul|Elam, Marcus L|Jo, Edward|Arjmandi, Bahram H|Salazar, Gloria|Grant, Samuel C|Contreras, Robert J|Lee, Won Jun|Kim, Jeong-Su
PMID: 27085776
Journal: Cell Mol Immunol. 2016 Sep;13(5):688-99.
Title: Expression of the novel adipokine C1qTNF-related protein 4 (CTRP4) suppresses colitis and colitis-associated colorectal cancer in mice.
Author: Luo, Yang|Wu, Xiaotong|Ma, Zhuang|Tan, Weifeng|Wang, Lanlan|Na, Daxiang|Zhang, Guoying|Yin, Ang|Huang, He|Xia, Dan|Zhang, Yingmei|Shi, Xueying|Wang, Lu
PMID: 27086950
Journal: Sci Rep. 2016 Apr 19;6:24675.
Title: Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-kappaB signalling pathway.
Author: Ruiz de Porras, Vicenc|Bystrup, Sara|Martinez-Cardus, Anna|Pluvinet, Raquel|Sumoy, Lauro|Howells, Lynne|James, Mark I|Iwuji, Chinenye|Manzano, Jose Luis|Layos, Laura|Buges, Cristina|Abad, Albert|Martinez-Balibrea, Eva
PMID: 27091625
Journal: Sci Rep. 2016 Apr 20;6:24720.
Title: miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
Author: El-Daly, Sherien M|Abba, Mohammed L|Patil, Nitin|Allgayer, Heike
PMID: 27095166
Journal: Biol Open. 2016 May 15;5(5):563-70.
Title: MicroRNA-204 modulates colorectal cancer cell sensitivity in response to 5-fluorouracil-based treatment by targeting high mobility group protein A2.
Author: Wu, Haijun|Liang, Yu|Shen, Lin|Shen, Liangfang
PMID: 27095441
Journal: Oncotarget. 2016 May 31;7(22):32902-15.
Title: Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer.
Author: Jung, Chan Kwon|Jung, Seung-Hyun|Yim, Seon-Hee|Jung, Ji-Han|Choi, Hyun Joo|Kang, Won-Kyung|Park, Sung-Won|Oh, Seong-Taek|Kim, Jun-Gi|Lee, Sug Hyung|Chung, Yeun-Jun
PMID: 27096956
Journal: Oncol Res. 2016;23(5):249-56.
Title: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression.
Author: Ren, Hongtao|Wang, Zhongwei|Zhang, Shuqun|Ma, Hongbing|Wang, Yali|Jia, Lijun|Li, Yiming
PMID: 27098148
Journal: Oncotarget. 2016 Jun 14;7(24):36168-36184.
Title: SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Author: Gueguinou, Maxime|Harnois, Thomas|Crottes, David|Uguen, Arnaud|Deliot, Nadine|Gambade, Audrey|Chantome, Aurelie|Haelters, Jean Pierre|Jaffres, Paul Alain|Jourdan, Marie Lise|Weber, Gunther|Soriani, Olivier|Bougnoux, Philippe|Mignen, Olivier|Bourmeyster, N
PMID: 27102434
Journal: Oncotarget. 2016 Jun 7;7(23):34300-15.
Title: Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer progression in inflammation-related microenvironment via inhibiting NF-kappaB activation through PI3K/Akt pathway.
Author: Sun, Yang|Zhao, Yue|Wang, Xiaoping|Zhao, Li|Li, Wenjun|Ding, Youxiang|Kong, Lingyi|Guo, Qinglong|Lu, Na
PMID: 27102438
Journal: Cell Rep. 2016 May 3;15(5):978-987.
Title: KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes.
Author: McKenzie, Andrew J|Hoshino, Daisuke|Hong, Nan Hyung|Cha, Diana J|Franklin, Jeffrey L|Coffey, Robert J|Patton, James G|Weaver, Alissa M
PMID: 27117408
Journal: Anticancer Res. 2016 May;36(5):2397-406.
Title: ZKSCAN3 Facilitates Liver Metastasis of Colorectal Cancer Associated with CEA-expressing Tumor.
Author: Kim, Chan Wook|Roh, Seon Ae|Tak, Ka Hee|Koh, Bo Min|Ha, Ye Jin|Cho, Dong-Hyung|Kim, Seon-Yong|Kim, Yong Sung|Kim, Jin Cheon
PMID: 27127149
Journal: Nutrients. 2016 May 2;8(5). pii: nu8050261.
Title: Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway.
Author: Tian, Yun|Wang, Keming|Fan, Yingrui|Wang, Yan|Sun, Liqun|Wang, Li|Wang, Jirong|Wang, Zhaoxia|Li, Juan|Ye, Ying|Ji, Guozhong
PMID: 27144580
Journal: Oncotarget. 2016 May 31;7(22):31755-71.
Title: The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer.
Author: Jiang, Bo|Zhang, Ting|Liu, Fen|Sun, Zhangzhang|Shi, Hanping|Hua, Dong|Yang, Chen
PMID: 27145365
Journal: Sci Rep. 2016 May 9;6:25631.
Title: Loss of the 14-3-3sigma is essential for LASP1-mediated colorectal cancer progression via activating PI3K/AKT signaling pathway.
Author: Shao, Ziyun|Cai, Yanjun|Xu, Lijun|Yao, Xueqing|Shi, Jiaolong|Zhang, Feifei|Luo, Yuhao|Zheng, Kehong|Liu, Jian|Deng, Fengliu|Li, Rui|Zhang, Lanzhi|Wang, Hui|Li, Mingyi|Ding, Yanqing|Zhao, Liang
PMID: 27156963
Journal: Am J Transl Res. 2016 Feb 15;8(2):742-8. eCollection 2016.
Title: BRD7: a novel tumor suppressor gene in different cancers.
Author: Yu, Xin|Li, Zheng|Shen, Jianxiong
PMID: 27158366
Journal: Am J Transl Res. 2016 Feb 15;8(2):1064-72. eCollection 2016.
Title: IL-13 induces the expression of 11betaHSD2 in IL-13Ralpha2 dependent manner and promotes the malignancy of colorectal cancer.
Author: Jiang, Li|Cheng, Qi|Zhang, Binhao|Zhang, Mingzhi
PMID: 27158392
Journal: Environ Toxicol Pharmacol. 2016 Jun;44:128-33.
Title: Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells.
Author: Kim, Joon Ki|Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Han, Xia|Fernando, Pattage Madushan Dilhara Jayatissa|Oh, Min Chang|Park, Jeong Eon|Shilnikova, Kristina|Boo, Sun Jin|Na, Soo-Young|Jeong, Yong Joo|Jeong, Seung Uk|Hyun, Jin Won
PMID: 27163731
Journal: J Cell Biochem. 2016 Dec;117(12):2854-2863.
Title: The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells.
Author: Park, Yang-Seo|Liu, Ziyu|Vasamsetti, Bala Murali Krishna|Cho, Nam Jeong
PMID: 27167250
Journal: Acta Pharmacol Sin. 2016 Jul;37(7):963-72.
Title: Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach.
Author: Qi, Quan|Li, Rui|Li, Hui-Ying|Cao, Yu-Bing|Bai, Ming|Fan, Xiao-Jing|Wang, Shu-Yan|Zhang, Bo|Li, Shao
PMID: 27180984
Journal: Am J Transl Res. 2016 Mar 15;8(3):1609-14. eCollection 2016.
Title: Houttuynia cordata Thunb reverses oxaliplatin-induced neuropathic pain in rat by regulating Th17/Treg balance.
Author: Wan, Cheng-Fu|Zheng, Li-Li|Liu, Yan|Yu, Xue
PMID: 27186286
Journal: Oncotarget. 2016 Jul 5;7(27):41306-41319.
Title: microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway.
Author: Chen, Yiyu|Jiang, Jingwen|Zhao, Mengyang|Luo, Xiaojun|Liang, Zixi|Zhen, Yan|Fu, Qiaofen|Deng, Xiaojie|Lin, Xian|Li, Libo|Luo, Rongcheng|Liu, Zhen|Fang, Weiyi
PMID: 27191497
Journal: J Cell Biochem. 2016 Dec;117(12):2875-2885.
Title: Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2 Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells.
Author: Semaan, Josiane|Pinon, Aline|Rioux, Benjamin|Hassan, Lama|Limami, Youness|Pouget, Christelle|Fagnere, Catherine|Sol, Vincent|Diab-Assaf, Mona|Simon, Alain|Liagre, Bertrand
PMID: 27192488
Journal: Mol Cancer Ther. 2016 Jun;15(6):1248-60.
Title: Inhibition of PI3K/BMX Cell Survival Pathway Sensitizes to BH3 Mimetics in SCLC.
Author: Potter, Danielle S|Galvin, Melanie|Brown, Stewart|Lallo, Alice|Hodgkinson, Cassandra L|Blackhall, Fiona|Morrow, Christopher J|Dive, Caroline
PMID: 27197306
Journal: Oncotarget. 2016 Jun 21;7(25):38143-38153.
Title: Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers.
Author: Hong, Shiao-Ya|Shih, Yi-Ping|Sun, Peng|Hsieh, Wang-Ju|Lin, Wen-Chang|Lo, Su Hao
PMID: 27203214
Journal: Carcinogenesis. 2016 Jul;37(7):731-739.
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Author: Tao, Yun|Messer, Jeannette S|Goss, Kathleen H|Hart, John|Bissonnette, Marc|Chang, Eugene B
PMID: 27207671
Journal: Int J Oncol. 2016 Jul;49(1):276-84.
Title: Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma.
Author: Harada, Koji|Ferdous, Tarannum|Harada, Toyoko|Ueyama, Yoshiya
PMID: 27210058
Journal: Oncol Rep. 2016 Jul;36(1):205-14.
Title: Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
Author: Lee, Moon Hee|Hong, Su-Hyun|Park, Cheol|Kim, Gi-Young|Leem, Sun-Hee|Choi, Sung Hyun|Keum, Young-Sam|Hyun, Jin Won|Kwon, Taeg Kyu|Hong, Sang Hoon|Choi, Yung Hyun
PMID: 27221553
Journal: Antioxid Redox Signal. 2016 Sep 10;25(8):467-84.
Title: Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects.
Author: Paillas, Salome|Ladjohounlou, Riad|Lozza, Catherine|Pichard, Alexandre|Boudousq, Vincent|Jarlier, Marta|Sevestre, Samuel|Le Blay, Marion|Deshayes, Emmanuel|Sosabowski, Jane|Chardes, Thierry|Navarro-Teulon, Isabelle|Mairs, Robert J|Pouget, Jean-Pierre
PMID: 27224059
Journal: J Exp Clin Cancer Res. 2016 May 25;35:84.
Title: Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication.
Author: Kaufhold, Samantha|Garban, Hermes|Bonavida, Benjamin
PMID: 27225481
Journal: Can J Physiol Pharmacol. 2016 Sep;94(9):929-35.
Title: Stanniocalcin 2 induces oxaliplatin resistance in colorectal cancer cells by upregulating P-glycoprotein.
Author: Yuan, Qiong|Zhan, Lin|Zhang, Li-Li|Wang, Qiang|Liu, Juan|Jiang, Zhen-Yu|Hu, Xia-Min|Yuan, Xin-Chu
PMID: 27245421
Journal: Oncotarget. 2016 Jul 12;7(28):43907-43923.
Title: Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice.
Author: Pajari, Anne-Maria|Paivarinta, Essi|Paavolainen, Lassi|Vaara, Elina|Koivumaki, Tuuli|Garg, Ritu|Heiman-Lindh, Anu|Mutanen, Marja|Marjomaki, Varpu|Ridley, Anne J
PMID: 27270323
Journal: Med Oncol. 2016 Jul;33(7):71.
Title: Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Author: Li, Zhe-Zhen|Bai, Long|Wang, Feng|Zhang, Zi-Chen|Wang, Fang|Zeng, Zhao-Lei|Zeng, Jun-Bo|Zhang, Dong-Sheng|Wang, Feng-Hua|Wang, Zhi-Qiang|Li, Yu-Hong|Shao, Jian-Yong|Xu, Rui-Hua
PMID: 27270901
Journal: Int J Oncol. 2016 Aug;49(2):646-56.
Title: Regulation of the RhoA/ROCK/AKT/beta-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.
Author: Song, Guang-Lin|Jin, Cong-Cong|Zhao, Wei|Tang, Yi|Wang, Ya-Lan|Li, Ming|Xiao, Ming|Li, Xian|Li, Qing-Shu|Lin, Xiao|Chen, Wen-Wen|Kuang, Jing
PMID: 27277835
Journal: Int J Oncol. 2016 Aug;49(2):639-45.
Title: Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Author: Esposito, Giuseppe|Gigli, Stefano|Seguella, Luisa|Nobile, Nicola|D'Alessandro, Alessandra|Pesce, Marcella|Capoccia, Elena|Steardo, Luca|Cirillo, Carla|Cuomo, Rosario|Sarnelli, Giovanni
PMID: 27279570
Journal: Dev Reprod. 2016 Mar;20(1):1-10.
Title: Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells.
Author: Oh, Iljoong|Cho, Hyunchul|Lee, Yonghoon|Cheon, Minseok|Park, Deokbae|Lee, Youngki
PMID: 27294206
Journal: BMC Cancer. 2016 Jun 13;16:366.
Title: PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
Author: Kuramochi, Hidekazu|Nakamura, Ayako|Nakajima, Go|Kaneko, Yuka|Araida, Tatsuo|Yamamoto, Masakazu|Hayashi, Kazuhiko
PMID: 27296289
Journal: Onco Targets Ther. 2016 May 24;9:2885-95.
Title: Antitumor effect of manumycin on colorectal cancer cells by increasing the reactive oxygen species production and blocking PI3K-AKT pathway.
Author: Zhang, Jingyu|Jiang, Hua|Xie, Li|Hu, Jing|Li, Li|Yang, Mi|Cheng, Lei|Liu, Baorui|Qian, Xiaoping
PMID: 27307747
Journal: J Cancer. 2016 May 7;7(8):928-34.
Title: Correlation of GOLPH3 Gene with Wnt Signaling Pathway in Human Colon Cancer Cells.
Author: Qiu, Cheng-Zhi|Wang, Ming-Zhen|Yu, Wai-Shi|Guo, Yan-Ta|Wang, Chun-Xiao|Yang, Xiao-Feng
PMID: 27313783
Journal: Cancer Biomark. 2016 Jun 7;17(1):1-10.
Title: Autophagy regulation and its role in gastric cancer and colorectal cancer.
Author: Zhou, Huangyan|Yuan, Min|Yu, Qiongfang|Zhou, Xiaoyan|Min, Weiping|Gao, Dian
PMID: 27314289
Journal: Physiol Genomics. 2016 Aug 1;48(8):545-53.
Title: Interactions between the colonic transcriptome, metabolome, and microbiome in mouse models of obesity-induced intestinal cancer.
Author: Pfalzer, Anna C|Kamanu, Frederick K|Parnell, Laurence D|Tai, Albert K|Liu, Zhenhua|Mason, Joel B|Crott, Jimmy W
PMID: 27317588
Journal: Nat Commun. 2016 Jun 20;7:11971.
Title: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
Author: Hao, Yujun|Samuels, Yardena|Li, Qingling|Krokowski, Dawid|Guan, Bo-Jhih|Wang, Chao|Jin, Zhicheng|Dong, Bohan|Cao, Bo|Feng, Xiujing|Xiang, Min|Xu, Claire|Fink, Stephen|Meropol, Neal J|Xu, Yan|Conlon, Ronald A|Markowitz, Sanford|Kinzler, Kenneth W|Velculesc
PMID: 27321283
Journal: Oncotarget. 2016 Jul 19;7(29):46219-46229.
Title: Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer.
Author: Jang, Hyun Joo|Hong, Eun Mi|Kim, Mikang|Kim, Jae Hyun|Jang, Juah|Park, Se Woo|Byun, Hyun Wu|Koh, Dong Hee|Choi, Min Ho|Kae, Sea Hyub|Lee, Jin
PMID: 27323826
Journal: Tumour Biol. 2016 Sep;37(9):12411-12422.
Title: EphA4-mediated signaling regulates the aggressive phenotype of irradiation survivor colorectal cancer cells.
Author: de Marcondes, Priscila Guimaraes|Bastos, Lilian Goncalves|de-Freitas-Junior, Julio Cesar Madureira|Rocha, Murilo Ramos|Morgado-Diaz, Jose Andres
PMID: 27323967
Journal: Oncotarget. 2016 Jul 19;7(29):46384-46400.
Title: Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis.
Author: Bozec, Dominique|Iuga, Alina C|Roda, Giulia|Dahan, Stephanie|Yeretssian, Garabet
PMID: 27344176
Journal: Oncol Lett. 2016 Jul;12(1):250-256.
Title: Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation.
Author: Jang, Hyun Joo|Hong, Eun Mi|Park, Se Woo|Byun, Hyun Woo|Koh, Dong Hee|Choi, Min Ho|Kae, Sea Hyub|Lee, Jin
PMID: 27347133
Journal: Mol Ther Oncolytics. 2016 Jun 15;3:16013.
Title: Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells.
Author: Warner, Susanne G|Haddad, Dana|Au, Joyce|Carson, Joshua S|O'Leary, Michael P|Lewis, Christina|Monette, Sebastien|Fong, Yuman
PMID: 27347556
Journal: World J Gastroenterol. 2016 Jun 28;22(24):5532-9.
Title: MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.
Author: Sheng, Wei-Zhong|Chen, Yu-Sheng|Tu, Chuan-Tao|He, Juan|Zhang, Bo|Gao, Wei-Dong
PMID: 27350731
Journal: Oncotarget. 2016 Jul 26;7(30):47699-47710.
Title: BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells.
Author: He, Kan|Chen, Dongshi|Ruan, Hang|Li, Xiangyun|Tong, Jingshan|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 27351224
Journal: Anticancer Res. 2016 Jul;36(7):3383-94.
Title: Enhanced TLR4 Expression on Colon Cancer Cells After Chemotherapy Promotes Cell Survival and Epithelial-Mesenchymal Transition Through Phosphorylation of GSK3beta.
Author: Chung, Yoon Hee|Kim, Daejin
PMID: 27354597
Journal: Chin J Integr Med. 2016 Jun 29. pii: 10.1007/s11655-016-2597-8.
Title: Tounong Powder () extracts induce G1 cell cycle arrest and apoptosis in LoVo cells.
Author: Fang, Liang-Hua|Liu, Shen-Lin|Wang, Rui-Ping|Hu, Shou-You|Ju, Wen-Zheng|Li, Chang-Yin
PMID: 27358203
Journal: Cancer Res. 2016 Sep 1;76(17):5019-29.
Title: Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody.
Author: Pupo, Emanuela|Ducano, Nadia|Lupo, Barbara|Vigna, Elisa|Avanzato, Daniele|Perera, Timothy|Trusolino, Livio|Lanzetti, Letizia|Comoglio, Paolo M
PMID: 27364553
Journal: Oncotarget. 2016 Aug 2;7(31):49597-49610.
Title: Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
Author: Wang, Chun Yan|Guo, Su Tang|Wang, Jia Yu|Yan, Xu Guang|Farrelly, Margaret|Zhang, Yuan Yuan|Liu, Fen|Yari, Hamed|La, Ting|Lei, Fu Xi|Jin, Lei|Zhang, Xu Dong|Jiang, Chen Chen
PMID: 27391062
Journal: Gene. 2016 Oct 10;591(1):123-128.
Title: Calycosin induces apoptosis in colorectal cancer cells, through modulating the ERbeta/MiR-95 and IGF-1R, PI3K/Akt signaling pathways.
Author: Zhao, Xinge|Li, Xin|Ren, Qianyao|Tian, Jing|Chen, Jian
PMID: 27393650
Journal: Acta Biomater. 2016 Sep 15;42:220-231.
Title: Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Ramasamy, Thiruganesh|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Yong, Chul Soon|Kim, Jong Oh|Kim, Hwan Mook
PMID: 27395829
Journal: Oncotarget. 2016 Aug 2;7(31):50490-50506.
Title: Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.
Author: Weidner, Philip|Sohn, Michaela|Gutting, Tobias|Friedrich, Teresa|Gaiser, Timo|Magdeburg, Julia|Kienle, Peter|Ruh, Hermelindis|Hopf, Carsten|Behrens, Hans-Michael|Rocken, Christoph|Hanoch, Tamar|Seger, Rony|Ebert, Matthias P A|Burgermeister, Elke
PMID: 27409167
Journal: Oncol Rep. 2016 Sep;36(3):1419-26.
Title: Thyroid hormone receptor beta1 suppresses proliferation and migration by inhibiting PI3K/Akt signaling in human colorectal cancer cells.
Author: Zhu, Lei|Tian, Guangang|Yang, Qin|De, Gejing|Zhang, Zhigang|Wang, Yahui|Nie, Huizhen|Zhang, Yanli|Yang, Xiaomei|Li, Jun
PMID: 27431682
Journal: Oncol Rep. 2016 Sep;36(3):1457-66.
Title: Crocodile blood extract induces the apoptosis of lung cancer cells through PTEN activity.
Author: Ou, Yuqian|Ho, Wing Shing
PMID: 27431918
Journal: Int J Clin Oncol. 2016 Dec;21(6):1091-1101.
Title: CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Author: Zhang, Xiaofei|Shimodaira, Hideki|Soeda, Hiroshi|Komine, Keigo|Takahashi, Hidekazu|Ouchi, Kota|Inoue, Masahiro|Takahashi, Masanobu|Takahashi, Shin|Ishioka, Chikashi
PMID: 27435270
Journal: Ann Oncol. 2016 Oct;27(10):1836-48.
Title: Prognostic role of tumor PIK3CA mutation in colorectal cancer: a systematic review and meta-analysis.
Author: Mei, Z B|Duan, C Y|Li, C B|Cui, L|Ogino, S
PMID: 27436848
Journal: Oncol Lett. 2016 Aug;12(2):783-787.
Title: Role of periostin in esophageal, gastric and colon cancer.
Author: Moniuszko, Tadeusz|Wincewicz, Andrzej|Koda, Mariusz|Domyslawska, Izabela|Sulkowski, Stanislaw
PMID: 27446351
Journal: J Surg Res. 2016 Jul;204(1):251-60.
Title: Sporadic early-onset colon cancer expresses unique molecular features.
Author: Jandova, Jana|Xu, Wenjie|Nfonsam, Valentine
PMID: 27451894
Journal: Oncol Rep. 2016 Sep;36(3):1526-34.
Title: A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Author: Dai, Bingling|Wang, Wenjie|Ma, Yujiao|Liu, Rui|Zhang, Yanmin
PMID: 27460008
Journal: Tumour Biol. 2016 Oct;37(10):13355-13368.
Title: Neutral endopeptidase (NEP) is differentially involved in biological activities and cell signaling of colon cancer cell lines derived from various stages of tumor development.
Author: Mizerska-Kowalska, Magdalena|Bojarska-Junak, Agnieszka|Jakubowicz-Gil, Joanna|Kandefer-Szerszen, Martyna
PMID: 27460083
Journal: BMC Cancer. 2016 Jul 26;16:531.
Title: Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells.
Author: Risberg, Karianne|Redalen, Kathrine Roe|Sonstevold, Linda|Bjornetro, Tonje|Solvernes, Janne|Ree, Anne Hansen
PMID: 27461218
Journal: Cancer Med. 2016 Sep;5(9):2417-26.
Title: Lentivirus-mediated shRNA interference of ghrelin receptor blocks proliferation in the colorectal cancer cells.
Author: Liu, An|Huang, Chenggang|Xu, Jia|Cai, Xuehong
PMID: 27464938
Journal: Exp Mol Med. 2016 Jul 29;48(7):e249.
Title: Sur8 mediates tumorigenesis and metastasis in colorectal cancer.
Author: Lee, Young-Mi|Kaduwal, Saluja|Lee, Kug Hwa|Park, Jong-Chan|Jeong, Woo-Jeong|Choi, Kang-Yell
PMID: 27469030
Journal: Biochem Biophys Res Commun. 2016 Sep 9;478(1):18-24.
Title: Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells.
Author: Park, Seong-Yeol|Bae, Young-Seuk
PMID: 27470586
Journal: Nutr Cancer. 2016 Oct;68(7):1234-46.
Title: Anticancer Activity of Buttermilk Against SW480 Colon Cancer Cells is Associated with Caspase-Independent Cell Death and Attenuation of Wnt, Akt, and ERK Signaling.
Author: Kuchta-Noctor, Anna M|Murray, Brian A|Stanton, Catherine|Devery, Rosaleen|Kelly, Phil M
PMID: 27472445
Journal: Protein Cell. 2016 Aug;7(8):571-85.
Title: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author: Shan, Jianzhen|Xuan, Yanyan|Zhang, Qi|Zhu, Chunpeng|Liu, Zhen|Zhang, Suzhan
PMID: 27472952
Journal: Oncotarget. 2016 Aug 30;7(35):57066-57076.
Title: Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells.
Author: Oh, Bo Young|Kim, So-Young|Lee, Yeo Song|Hong, Hye Kyung|Kim, Tae Won|Kim, Seok Hyung|Lee, Woo Yong|Cho, Yong Beom
PMID: 27494849
Journal: Tumour Biol. 2016 Oct;37(10):14089-14101.
Title: Experimental verification of a predicted novel microRNA located in human PIK3CA gene with a potential oncogenic function in colorectal cancer.
Author: Saleh, Ali Jason|Soltani, Bahram M|Dokanehiifard, Sadat|Medlej, Abdallah|Tavalaei, Mahmoud|Mowla, Seyed Javad
PMID: 27511117
Journal: Oncotarget. 2016 Sep 27;7(39):63124-63137.
Title: DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling.
Author: Huang, Shiu-Wen|Lien, Jin-Cherng|Kuo, Sheng-Chu|Huang, Tur-Fu
PMID: 27517319
Journal: Oncotarget. 2016 Sep 13;7(37):59766-59780.
Title: Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells.
Author: Goncalves-Ribeiro, Samuel|Diaz-Maroto, Natalia Guillen|Berdiel-Acer, Mireia|Soriano, Antonio|Guardiola, Jordi|Martinez-Villacampa, Mercedes|Salazar, Ramon|Capella, Gabriel|Villanueva, Alberto|Martinez-Balibrea, Eva|Mollevi, David G
PMID: 27517495
Journal: Mol Cell Biochem. 2016 Oct;421(1-2):1-18.
Title: Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenografts.
Author: Tankiewicz-Kwedlo, A|Hermanowicz, J|Surazynski, A|Rozkiewicz, D|Pryczynicz, A|Domaniewski, T|Pawlak, K|Kemona, A|Pawlak, D
PMID: 27543111
Journal: Carcinogenesis. 2016 Nov 1;37(11):1079-1088.
Title: Downregulation of AIF by HIF-1 contributes to hypoxia-induced epithelial-mesenchymal transition of colon cancer.
Author: Xiong, Zhong|Guo, Meng|Yu, Yun|Zhang, Fei-Fei|Ge, Meng-Kai|Chen, Guo-Qiang|Shen, Shao-Ming
PMID: 27543779
Journal: Radiat Res. 2016 Sep;186(3):292-301.
Title: MiR-29a Regulates Radiosensitivity in Human Intestinal Cells by Targeting PTEN Gene.
Author: Wang, Juan|Xu, Jinping|Fu, Jiamei|Yuan, Dexiao|Guo, Fei|Zhou, Cuiping|Shao, Chunlin
PMID: 27548517
Journal: World J Surg Oncol. 2016 Aug 23;14(1):221.
Title: Effect of a chemical inhibitor of human phosphatidylethanolamine-binding protein 4 on radiosensitivity of rectal cancer cells.
Author: Qiu, Jianming|Tao, Yong|Yang, Guangen|Xu, Kan|Lin, A Li|Li, Liuyu
PMID: 27553494
Journal: Oncotarget. 2016 Oct 11;7(41):66660-66678.
Title: Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.
Author: Hu, Liang|Wang, Ruo-Yu|Cai, Jian|Feng, Dan|Yang, Guang-Zhen|Xu, Qing-Guo|Zhai, Yan-Xia|Zhang, Yu|Zhou, Wei-Ping|Cai, Qing-Ping
PMID: 27556502
Journal: Oncotarget. 2016 Sep 20;7(38):61509-61519.
Title: Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells.
Author: Jing, Zhao|Fei, Weiqiang|Zhou, Jichun|Zhang, Lumin|Chen, Liuxi|Zhang, Xiaomin|Liang, Xiao|Xie, Jiansheng|Fang, Yong|Sui, Xinbing|Han, Weidong|Pan, Hongming
PMID: 27557491
Journal: Biochim Biophys Acta. 2016 Nov;1863(11):2749-2757.
Title: Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels: Mechanism of 5-fluorouracil resistance in colorectal tumor cells.
Author: Hoshiba, Takashi|Tanaka, Masaru
PMID: 27558478
Journal: BMC Cancer. 2016 Aug 25;16(1):683.
Title: High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Author: Padhan, Narendra|Nordling, Torbjorn E M|Sundstrom, Magnus|Akerud, Peter|Birgisson, Helgi|Nygren, Peter|Nelander, Sven|Claesson-Welsh, Lena
PMID: 27562229
Journal: Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20.
Title: mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Author: Jin, Zhe-Zhu|Wang, Wei|Fang, Di-Long|Jin, Yong-Jun
PMID: 27565731
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: J Hematol Oncol. 2016 Aug 31;9(1):76.
Title: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway.
Author: Liu, Jing|Pan, Changqie|Guo, Lihong|Wu, Mengwan|Guo, Jing|Peng, Sheng|Wu, Qianying|Zuo, Qiang
PMID: 27581375
Journal: Oncotarget. 2016 Oct 18;7(42):68546-68558.
Title: Specific inhibition of p110alpha subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers.
Author: Fernandes, Maria Sofia|Melo, Soraia|Velho, Sergia|Carneiro, Patricia|Carneiro, Fatima|Seruca, Raquel
PMID: 27602501
Journal: Oncogenesis. 2016 Sep 12;5(9):e258.
Title: The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition.
Author: Komiya, Y|Onodera, Y|Kuroiwa, M|Nomimura, S|Kubo, Y|Nam, J-M|Kajiwara, K|Nada, S|Oneyama, C|Sabe, H|Okada, M
PMID: 27617642
Journal: Sci Rep. 2016 Sep 14;6:33204.
Title: Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents.
Author: Zhang, Xiao-Fei|Sun, Rong-Qin|Jia, Yi-Fan|Chen, Qing|Tu, Rong-Fu|Li, Ke-Ke|Zhang, Xiao-Dong|Du, Run-Lei|Cao, Ri-Hui
PMID: 27625151
Journal: Oncotarget. 2016 Oct 18;7(42):68749-68767.
Title: Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
Author: Moench, Romana|Grimmig, Tanja|Kannen, Vinicius|Tripathi, Sudipta|Faber, Marc|Moll, Eva-Maria|Chandraker, Anil|Lissner, Reinhard|Germer, Christoph-Thomas|Waaga-Gasser, Ana Maria|Gasser, Martin
PMID: 27626684
Journal: PLoS One. 2016 Sep 14;11(9):e0162077.
Title: Telomere Length, TERT, and miRNA Expression.
Author: Slattery, Martha L|Herrick, Jennifer S|Pellatt, Andrew J|Wolff, Roger K|Mullany, Lila E
PMID: 27627813
Journal: Apoptosis. 2016 Nov;21(11):1291-1301.
Title: Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
Author: Chen, Lei|Meng, Yue|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Zhang, Fenglei|Cheng, Hairong|Zhou, Yifa
PMID: 27629794
Journal: Mol Ther. 2016 Dec;24(12):2064-2077.
Title: Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer.
Author: Yue, Ben|Cai, Donglan|Liu, Chenchen|Fang, Changyi|Yan, Dongwang
PMID: 27633443
Journal: Oncol Rep. 2016 Nov;36(5):2723-2730.
Title: Glucose-regulated protein 78 contributes to the proliferation and tumorigenesis of human colorectal carcinoma via AKT and ERK pathways.
Author: Zhou, Xuan|Xing, Xiaoming|Zhang, Shuping|Liu, Lili|Wang, Chengqin|Li, Lin|Ji, Qiuxia|Liu, Huamin
PMID: 27634156
Journal: Oncotarget. 2016 Oct 18;7(42):68781-68791.
Title: CB2 cannabinoid receptor activation promotes colon cancer progression via AKT/GSK3beta signaling pathway.
Author: Martinez-Martinez, Esther|Martin-Ruiz, Asuncion|Martin, Paloma|Calvo, Virginia|Provencio, Mariano|Garcia, Jose M
PMID: 27634891
Journal: J Exp Clin Cancer Res. 2016 Sep 20;35(1):148.
Title: TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway.
Author: Song, Guohe|Xu, Shifeng|Zhang, Hong|Wang, Yupeng|Xiao, Chao|Jiang, Tao|Wu, Leilei|Zhang, Tao|Sun, Xing|Zhong, Lin|Zhou, Chongzhi|Wang, Zhaowen|Peng, Zhihai|Chen, Jian|Wang, Xiaoliang
PMID: 27644693
Journal: Oncotarget. 2016 Nov 8;7(45):73739-73753.
Title: The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer.
Author: Ottman, Richard|Levy, Jenna|Grizzle, William E|Chakrabarti, Ratna
PMID: 27650539
Journal: Autophagy. 2016 Dec;12(12):2498-2499.
Title: Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer.
Author: Wang, Kui|Gao, Wei|Dou, Qianhui|Chen, Haining|Li, Qifu|Nice, Edouard C|Huang, Canhua
PMID: 27657889
Journal: Oncotarget. 2016 Oct 25;7(43):70601-70612.
Title: Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer.
Author: Roseweir, Antonia K|Powell, Arfon G M T|Bennett, Lindsay|Van Wyk, Hester C|Park, James|McMillan, Donald C|Horgan, Paul G|Edwards, Joanne
PMID: 27661110
Journal: Oncotarget. 2016 Nov 1;7(44):71400-71416.
Title: STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways.
Author: Chen, Bing|Zeng, Xiao|He, Yu|Wang, Xixi|Liang, Ziwei|Liu, Jingjing|Zhang, Peng|Zhu, Hongxia|Xu, Ningzhi|Liang, Shufang
PMID: 27662663
Journal: Toxicol Appl Pharmacol. 2016 Nov 15;311:106-112.
Title: Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells.
Author: Dai, Jin|Van Wie, Peter G|Fai, Leonard Yenwong|Kim, Donghern|Wang, Lei|Poyil, Pratheeshkumar|Luo, Jia|Zhang, Zhuo
PMID: 27664007
Journal: PLoS One. 2016 Sep 26;11(9):e0159927.
Title: The Association of CXC Receptor 4 Mediated Signaling Pathway with Oxaliplatin-Resistant Human Colorectal Cancer Cells.
Author: Huang, Wen-Shih|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Kuo, Yi-Hung|Tung, Shui-Yi|Shen, Chien-Heng|Hsieh, Yung-Yu|Teng, Chih-Chuan|Lee, Kam-Fai|Chen, Te-Chuan|Lee, Ko-Chao|Kuo, Hsing-Chun
PMID: 27668882
Journal: J Exp Clin Cancer Res. 2016 Sep 27;35(1):152.
Title: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways.
Author: Yang, Run-Wei|Zeng, Ying-Yue|Wei, Wen-Ting|Cui, Yan-Mei|Sun, Hui-Ying|Cai, Yue-Long|Nian, Xin-Xin|Hu, Yun-Teng|Quan, Yu-Ping|Jiang, Sheng-Lu|Wang, Meng|Zhao, Ya-Li|Qiu, Jun-Feng|Li, Ming-Xuan|Zhang, Jia-Huan|He, Mei-Rong|Liang, Li|Ding, Yan-Qing|Liao, Wen
PMID: 27669982
Journal: Apoptosis. 2016 Dec;21(12):1398-1407.
Title: Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
Author: Liu, Yan|Bi, Tingting|Wang, Zheng|Wu, Guoliang|Qian, Liqiang|Gao, Quangen|Shen, Genhai
PMID: 27671687
Journal: Gastroenterol Res Pract. 2016;2016:2102674.
Title: Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans.
Author: Ashktorab, Hassan|Shakoori, Afnan|Zarnogi, Shatha|Sun, Xueguang|Varma, Sudhir|Lee, Edward|Shokrani, Babak|Laiyemo, Adeyinka O|Washington, Kareem|Brim, Hassan
PMID: 27688749
Journal: Oncotarget. 2016 Nov 15;7(46):75659-75671.
Title: Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
Author: Zhang, Jianbin|Wang, Jigang|Xu, Jian|Lu, Yuanqiang|Jiang, Jiukun|Wang, Liming|Shen, Han-Ming|Xia, Dajing
PMID: 27689333
Journal: Biomed Pharmacother. 2016 Dec;84:601-607.
Title: Odontogenic ameloblast-associated protein (ODAM) inhibits human colorectal cancer growth by promoting PTEN elevation and inactivating PI3K/AKT signaling.
Author: Yu, Minhao|Mu, Yifei|Qi, Yang|Qin, Shaolan|Qiu, Yier|Cui, Ran|Zhong, Ming
PMID: 27694004
Journal: Oncol Lett. 2016 Oct;12(4):2463-2474.
Title: Effect of API-1 and FR180204 on cell proliferation and apoptosis in human DLD-1 and LoVo colorectal cancer cells.
Author: Saglam, Atiye Seda Yar|Alp, Ebru|Elmazoglu, Zubeyir|Menevse, Emine Sevda
PMID: 27698814
Journal: Oncotarget. 2016 Nov 15;7(46):75685-75697.
Title: Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy.
Author: Li, Gen|Wu, Anqing|Qi, Dandan|Cui, Fengmei|Zeng, Yanan|Xie, Fang|Wu, Hongya|Gu, Yongping|Chen, Qiu|Zhang, Xueguang
PMID: 27708223
Journal: Eur J Cancer. 2016 Nov;68:38-50.
Title: 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells.
Author: Zhao, Yueliang|Fan, Daming|Ru, Beibei|Cheng, Ka-Wing|Hu, Shuting|Zhang, Jiangwen|Li, Edmund T S|Wang, Mingfu
PMID: 27710830
Journal: Oncotarget. 2016 Nov 8;7(45):73525-73540.
Title: Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.
Author: Hoekstra, Elmer|Das, Asha M|Willemsen, Marcella|Swets, Marloes|Kuppen, Peter J K|van der Woude, Christien J|Bruno, Marco J|Shah, Jigisha P|Ten Hagen, Timo L M|Chisholm, John D|Kerr, William G|Peppelenbosch, Maikel P|Fuhler, Gwenny M
PMID: 27716613
Journal: BMC Cancer. 2016 Oct 12;16(1):791.
Title: Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
Author: Ding, Chenbo|Li, Longmei|Yang, Taoyu|Fan, Xiaobo|Wu, Guoqiu
PMID: 27729020
Journal: Mol Med Rep. 2016 Nov;14(5):4559-4566.
Title: Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.
Author: Yang, Lin|Liu, Yanqing|Wang, Mei|Qian, Yayun|Dong, Xiaoyun|Gu, Hao|Wang, Haibo|Guo, Shiyu|Hisamitsu, Tadashi
PMID: 27748879
Journal: Oncol Rep. 2016 Dec;36(6):3559-3567.
Title: Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.
Author: Fan, Xiang-Jun|Wang, Yao|Wang, Lei|Zhu, Mingyan
PMID: 27748934
Journal: Oncotarget. 2016 Nov 1;7(44):72229-72241.
Title: Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer.
Author: Park, Young-Lan|Park, Sun-Young|Lee, Seung-Hyun|Kim, Rul-Bin|Kim, Joong-Keun|Rew, Sung-Yoon|Myung, Dae-Seong|Cho, Sung-Bum|Lee, Wan-Sik|Kim, Hyun-Soo|Joo, Young-Eun
PMID: 27750216
Journal: Neoplasia. 2016 Nov;18(11):654-665.
Title: Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Author: Toda, Kosuke|Kawada, Kenji|Iwamoto, Masayoshi|Inamoto, Susumu|Sasazuki, Takehiko|Shirasawa, Senji|Hasegawa, Suguru|Sakai, Yoshiharu
PMID: 27764698
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016 Nov;32(11):1503-1506.
Title: [Overexpression of aplysia Ras homolog I (ARHI) increases apoptosis in colon cancer SW480 cells].
Author: Chen, Xin|Jiang, Zheng
PMID: 27774944
Journal: Oncol Rep. 2016 Dec;36(6):3619-3626.
Title: Angiomotin promotes the malignant potential of colon cancer cells by activating the YAP-ERK/PI3K-AKT signaling pathway.
Author: Zhang, Yan|Yuan, Jun|Zhang, Xinli|Yan, Futang|Huang, Minggang|Wang, Tao|Zheng, Xiao|Zhang, Ming
PMID: 27779692
Journal: Oncotarget. 2016 Nov 22;7(47):77087-77095.
Title: Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application.
Author: Deng, Fengliu|Ouyang, Mingwen|Wang, Xiaofei|Yao, Xueqing|Chen, Yeming|Tao, Tao|Sun, Xuegang|Xu, Lijun|Tang, Jing|Zhao, Liang
PMID: 27780923
Journal: Oncotarget. 2016 Nov 22;7(47):77815-77824.
Title: Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells.
Author: Li, Jian-Ping|Huang, Zhi-Jun|Lu, Xing-Sheng|Zhou, Yi-Chan|Shao, Yun|He, Xiao-Pu|Chen, Su-Rong|Wang, Dong-Dong|Qin, Li-Sen|Sun, Wei-Hao
PMID: 27780925
Journal: Sci Rep. 2016 Nov 4;6:36544.
Title: Probing the PI3K/Akt/mTor pathway using (31)P-NMR spectroscopy: routes to glycogen synthase kinase 3.
Author: Phyu, Su M|Tseng, Chih-Chung|Fleming, Ian N|Smith, Tim A D
PMID: 27811956
Journal: Am J Cancer Res. 2016 Oct 1;6(10):2299-2309. eCollection 2016.
Title: LncRNA CRNDE promotes hepatic carcinoma cell proliferation, migration and invasion by suppressing miR-384.
Author: Chen, Zili|Yu, Chao|Zhan, Lei|Pan, Yaozhen|Chen, Ling|Sun, Chengyi
PMID: 27822419
Journal: EPMA J. 2016 Nov 10;7:22.
Title: The role of testosterone in colorectal carcinoma: pathomechanisms and open questions.
Author: Roshan, Mohsin H K|Tambo, Amos|Pace, Nikolai P
PMID: 27833666
Journal: Oncotarget. 2016 Dec 6;7(49):81156-81171.
Title: Gankyrin sustains PI3K/GSK-3beta/beta-catenin signal activation and promotes colorectal cancer aggressiveness and progression.
Author: He, Feng|Chen, Huacui|Yang, Ping|Wu, Qianlong|Zhang, Tong|Wang, Chengxing|Wei, Jianchang|Chen, Zhuanpeng|Hu, He|Li, Wanglin|Cao, Jie
PMID: 27835604
Journal: Oncotarget. 2016 Dec 20;7(51):85124-85141.
Title: Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer.
Author: Tury, Sandrine|Becette, Veronique|Assayag, Franck|Vacher, Sophie|Benoist, Camille|Kamal, Maud|Marangoni, Elisabetta|Bieche, Ivan|Lerebours, Florence|Callens, Celine
PMID: 27835884
Journal: Oncotarget. 2016 Dec 27;7(52):86134-86147.
Title: Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling.
Author: Zhang, Chuan|Wang, Yong|Feng, YiFei|Zhang, Yue|Ji, Bing|Wang, Sen|Sun, Ye|Zhu, Chunyan|Zhang, Dongsheng|Sun, Yueming
PMID: 27863385
Journal: Eur Rev Med Pharmacol Sci. 2016 Nov;20(21):4474-4481.
Title: Nox1 promotes colon cancer cell metastasis via activation of the ADAM17 pathway.
Author: Wang, H-P|Wang, X|Gong, L-F|Chen, W-J|Hao, Z|Feng, S-W|Wu, Y-B|Ye, T|Cai, Y-K
PMID: 27874952
Journal: Oncotarget. 2016 Dec 27;7(52):87147-87160.
Title: Negative feedback between TAp63 and Mir-133b mediates colorectal cancer suppression.
Author: Dai, Jing|Wu, Hao|Zhang, Yi|Gao, Kai|Hu, Gui|Guo, Yihang|Lin, Changwei|Li, Xiaorong
PMID: 27894087
Journal: Oncol Lett. 2016 Nov;12(5):3771-3778.
Title: Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells.
Author: Yang, Lin|Liu, Yanqing|Wang, Mei|Qian, Yayun|Dai, Xiaojun|Zhu, Yaodong|Chen, Jue|Guo, Shiyu|Hisamitsu, Tadashi
PMID: 27895729
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(11):1361-1365.
Title: [New Classification for Advanced Colorectal Cancer Using CancerPlex(R)Genomic Tests].
Author: Kameyama, Hitoshi|Shimada, Yoshifumi|Ichikawa, Hiroshi|Nagahashi, Masayuki|Sakata, Jun|Kobayashi, Takashi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa|Okuda, Shujiro|Ling, Yiwei|Izutsu, Hiroshi|Kodama, Keisuke|Nakada, Mitsutaka|Wakai, Toshifumi
PMID: 27899776
Journal: Nature. 2016 Dec 12. pii: nature20597.
Title: NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
Author: Karki, Rajendra|Man, Si Ming|Malireddi, R K Subbarao|Kesavardhana, Sannula|Zhu, Qifan|Burton, Amanda R|Sharma, Bhesh Raj|Qi, Xiaopeng|Pelletier, Stephane|Vogel, Peter|Rosenstiel, Philip|Kanneganti, Thirumala-Devi
PMID: 27951586
Journal: Curr Oncol. 2016 Dec;23(6):e571-e575.
Title: Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author: Sheffield, B S|Tessier-Cloutier, B|Li-Chang, H|Shen, Y|Pleasance, E|Kasaian, K|Li, Y|Jones, S J M|Lim, H J|Renouf, D J|Huntsman, D G|Yip, S|Laskin, J|Marra, M|Schaeffer, D F
PMID: 28050146
Journal: Biomed Res Int. 2016;2016:8145495.
Title: (125)I Seeds Radiation Induces Paraptosis-Like Cell Death via PI3K/AKT Signaling Pathway in HCT116 Cells.
Author: Hu, Lelin|Wang, Hao|Zhao, Yong|Wang, Junjie
PMID: 28078301
Journal: Oncol Lett. 2016 Dec;12(6):4850-4856.
Title: Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity.
Author: Kim, Chul Jang|Tambe, Yukihiro|Mukaisho, Ken-Ichi|Sugihara, Hiroyuki|Kawauchi, Akihiro|Inoue, Hirokazu
PMID: 28105192
Journal: Cell Mol Gastroenterol Hepatol. 2015 Nov 14;2(1):11-21.
Title: New and Unexpected Biological Functions for the Src-Homology 2 Domain-Containing Phosphatase SHP-2 in the Gastrointestinal Tract.
Author: Coulombe, Genevieve|Rivard, Nathalie
PMID: 28174704
Journal: Gastrointest Cancer (Jersey City). 2016;1(1). Epub 2016 Aug 3.
Title: Gene Expression Analysis of Sporadic Early-Onset Rectal Adenocarcinoma.
Author: Nfonsam, V|Xu, W|Koblinski, J|Jandova, J
PMID: 28239680
Journal: Oncol Res. 2016 Oct 27;24(6):437-445.
Title: Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway.
Author: Zhao, Ping|Guan, Hai-Tao|Dai, Zhi-Jun|Ma, Yu-Guang|Liu, Xiao-Xu|Wang, Xi-Jing
PMID: 28281964
Journal: Integr Med Res. 2016 Dec;5(4):284-292.
Title: Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells.
Author: Yim, Nam-Hui|Gu, Min Jung|Hwang, Youn-Hwan|Cho, Won-Kyung|Ma, Jin Yeul
PMID: 28462130
Journal: Zhong Yao Cai. 2016 Jul;39(7):1618-22.
Title: [Experiment on Jianpi Qingre Huoxue Decoction Drug Serum Regulates SW480 Cell Proliferation,Apoptosis,Cycle and the Expression of beta-Catenin by Altering PI3K/Akt Signal Pathway].
Author: Zhang, Tao|Chen, Yu|Wang, Xiao-ping|Ping, Qian|Lin, Chun-li|Zhuo, Shao-yuan
PMID: 30204364
Journal: Ann Surg Oncol. 2017 Feb;24(2):594-602.
Title: Overexpression of Transmembrane Protein BST2 is Associated with Poor Survival of Patients with Esophageal, Gastric, or Colorectal Cancer.
Author: Mukai, Shoichiro|Oue, Naohide|Oshima, Takashi|Mukai, Risa|Tatsumoto, Yoshiko|Sakamoto, Naoya|Sentani, Kazuhiro|Tanabe, Kazuaki|Egi, Hiroyuki|Hinoi, Takao|Ohdan, Hideki|Yasui, Wataru
PMID: 26832883
Journal: Oncotarget. 2017 Jul 25;8(30):48650-48659.
Title: PTRF suppresses the progression of colorectal cancers.
Author: Wang, Fengyun|Zheng, Yongqiu|Orange, Matthew|Yang, Chunlin|Yang, Bin|Liu, Jiong|Tan, Tao|Ma, Xiangxue|Chen, Tin|Yin, Xiaolan|Tang, Xudong|Zhu, Hua
PMID: 27203393
Journal: Clin Cancer Res. 2017 Jan 1;23(1):104-115.
Title: BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.
Author: Barras, David|Missiaglia, Edoardo|Wirapati, Pratyaksha|Sieber, Oliver M|Jorissen, Robert N|Love, Chris|Molloy, Peter L|Jones, Ian T|McLaughlin, Stephen|Gibbs, Peter|Guinney, Justin|Simon, Iris M|Roth, Arnaud D|Bosman, Fred T|Tejpar, Sabine|Delorenzi, Maur
PMID: 27354468
Journal: J Ethnopharmacol. 2017 Apr 18;202:20-27.
Title: Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells.
Author: Cao, Zhi-Xing|Yang, Yu-Ting|Yu, Si|Li, Yu-Zhi|Wang, Wen-Wen|Huang, Jing|Xie, Xiao-Fang|Xiong, Liang|Lei, Song|Peng, Cheng
PMID: 27416805
Journal: Clin Cancer Res. 2017 Jan 15;23(2):399-406.
Title: PI3K/Akt/mTOR Signaling and Plasma Membrane Proteins Are Implicated in Responsiveness to Adjuvant Dendritic Cell Vaccination for Metastatic Colorectal Cancer.
Author: Qian, David C|Xiao, Xiangjun|Byun, Jinyoung|Suriawinata, Arief A|Her, Stephanie C|Amos, Christopher I|Barth, Richard J Jr
PMID: 27435399
Journal: Oncotarget. 2017 Jan 31;8(5):7502-7520.
Title: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers.
Author: Zhao, Shuang|Chen, Shu-Rui|Yang, Xue-Feng|Shen, Dao-Fu|Takano, Yasuo|Su, Rong-Jian|Zheng, Hua-Chuan
PMID: 27447746
Journal: Oncotarget. 2017 Jul 25;8(30):48782-48793.
Title: Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis.
Author: Zhao, Yiqing|Scott, Anthony|Zhang, Peng|Hao, Yujun|Feng, Xiujing|Somasundaram, Saigopal|Khalil, Ahmad M|Willis, Joseph|Wang, Zhenghe
PMID: 27447856
Journal: Cell Mol Immunol. 2017 Jan;14(1):127-142.
Title: The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway.
Author: Ratsimandresy, Rojo A|Indramohan, Mohanalaxmi|Dorfleutner, Andrea|Stehlik, Christian
PMID: 27524110
Journal: Anticancer Drugs. 2017 Jan;28(1):66-74.
Title: Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author: Guo, Xiaoqing|Meng, Yue|Sheng, Xiaotong|Guan, Yuan|Zhang, Fenglei|Han, Zhen|Kang, Yuying|Tai, Guihua|Zhou, Yifa|Cheng, Hairong
PMID: 27603596
Journal: J Cell Biochem. 2017 Mar;118(3):442-445.
Title: The Role of EphA4 Signaling in Radiation-Induced EMT-Like Phenotype in Colorectal Cancer Cells.
Author: de Marcondes, Priscila Guimaraes|Morgado-Diaz, Jose Andres
PMID: 27632701
Journal: J Cell Sci. 2017 Jan 1;130(1):203-218.
Title: Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
Author: Riedl, Angelika|Schlederer, Michaela|Pudelko, Karoline|Stadler, Mira|Walter, Stefanie|Unterleuthner, Daniela|Unger, Christine|Kramer, Nina|Hengstschlager, Markus|Kenner, Lukas|Pfeiffer, Dagmar|Krupitza, Georg|Dolznig, Helmut
PMID: 27663511
Journal: Mod Pathol. 2017 Jan;30(1):113-122.
Title: Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis.
Author: Pai, Reetesh K|Cheng, Yu-Wei|Jakubowski, Maureen A|Shadrach, Bonnie L|Plesec, Thomas P|Pai, Rish K
PMID: 27713420
Journal: J Clin Pathol. 2017 May;70(5):410-416.
Title: mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression.
Author: Sticz, Tamas|Molnar, Anna|Mark, Agnes|Hajdu, Melinda|Nagy, Noemi|Vegso, Gyula|Micsik, Tamas|Kopper, Laszlo|Sebestyen, Anna
PMID: 27729429
Journal: Phytother Res. 2017 Jan;31(1):90-99.
Title: Daikenchuto (TU-100) Suppresses Tumor Development in the Azoxymethane and APC(min/+) Mouse Models of Experimental Colon Cancer.
Author: Hasebe, Takumu|Matsukawa, Jun|Ringus, Daina|Miyoshi, Jun|Hart, John|Kaneko, Atsushi|Yamamoto, Masahiro|Kono, Toru|Fujiya, Mikihiro|Kohgo, Yutaka|Wang, Chong-Zi|Yuan, Chun-Su|Bissonnette, Marc|Musch, Mark W|Chang, Eugene B
PMID: 27730672
Journal: Cancer Res. 2017 Jan 1;77(1):142-152.
Title: Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
Author: Kang, Dong Woo|Lee, Shin Wha|Hwang, Won Chan|Lee, Bo Hui|Choi, Yong-Seok|Suh, Young-Ah|Choi, Kang-Yell|Min, Do Sik
PMID: 27793841
Journal: Mol Cancer Ther. 2017 Feb;16(2):344-356.
Title: Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities.
Author: Talbert, Erin E|Yang, Jennifer|Mace, Thomas A|Farren, Matthew R|Farris, Alton B|Young, Gregory S|Elnaggar, Omar|Che, Zheng|Timmers, Cynthia D|Rajasekera, Priyani|Maskarinec, Jennifer M|Bloomston, Mark|Bekaii-Saab, Tanios|Guttridge, Denis C|Lesinski, Grego
PMID: 27811010
Journal: J Nutr Biochem. 2017 Jan;39:126-133.
Title: Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity.
Author: Niku, Mikael|Pajari, Anne-Maria|Sarantaus, Laura|Paivarinta, Essi|Storvik, Markus|Heiman-Lindh, Anu|Suokas, Santeri|Nystrom, Minna|Mutanen, Marja
PMID: 27833053
Journal: Oncol Rep. 2017 Jan;37(1):281-288.
Title: Resveratrol analogue, HS-1793, induces apoptotic cell death and cell cycle arrest through downregulation of AKT in human colon cancer cells.
Author: Kim, Dong Hwan|Kim, Min Jeong|Sung, Bokyung|Suh, Hongsuk|Jung, Jee H|Chung, Hae Young|Kim, Nam Deuk
PMID: 27840966
Journal: Oncol Rep. 2017 Jan;37(1):631-639.
Title: MicroRNA-302a enhances 5-fluorouracil-induced cell death in human colon cancer cells.
Author: Liu, Na|Li, Jie|Zhao, Zhenghao|Han, Jia|Jiang, Ting|Chen, Yanke|Hou, Ni|Huang, Chen
PMID: 27840990
Journal: Toxicol Lett. 2017 Jan 4;265:53-60.
Title: Microcystin-LR promotes epithelial-mesenchymal transition in colorectal cancer cells through PI3-K/AKT and SMAD2.
Author: Ren, Yan|Yang, Mengli|Chen, Meng|Zhu, Qiangqiang|Zhou, Lihua|Qin, Wei|Wang, Ting
PMID: 27856280
Journal: Cancer Sci. 2017 Jan;108(1):143-150.
Title: Clinicopathological significance of SPC18 in colorectal cancer: SPC18 participates in tumor progression.
Author: Hattori, Takuya|Sentani, Kazuhiro|Naohide, Oue|Sakamoto, Naoya|Yasui, Wataru
PMID: 27859949
Journal: J Pineal Res. 2017 Mar;62(2).
Title: Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-kappaB/iNOS signaling pathways.
Author: Gao, Yue|Xiao, Xiangsheng|Zhang, Changlin|Yu, Wendan|Guo, Wei|Zhang, Zhifeng|Li, Zhenglin|Feng, Xu|Hao, Jiaojiao|Zhang, Kefang|Xiao, Bingyi|Chen, Miao|Huang, Wenlin|Xiong, Shunbin|Wu, Xiaojun|Deng, Wuguo
PMID: 27865009
Journal: Int J Oncol. 2017 Jan;50(1):5-14.
Title: Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Author: Haggblad Sahlberg, Sara|Mortensen, Anja C|Haglof, Jakob|Engskog, Mikael K R|Arvidsson, Torbjorn|Pettersson, Curt|Glimelius, Bengt|Stenerlow, Bo|Nestor, Marika
PMID: 27878243
Journal: Nutr Cancer. 2017 Jan;69(1):44-55.
Title: Koelreuteria Formosana Extract Induces Growth Inhibition and Cell Death in Human Colon Carcinoma Cells via G2/M Arrest and LC3-II Activation-Dependent Autophagy.
Author: Horng, Chi-Ting|Wu, Yueh-Jung|Chen, Pei-Ni|Chu, Shu-Chen|Tsai, Chun-Miao|Hsieh, Yih-Shou
PMID: 27880045
Journal: Biochem Biophys Res Commun. 2017 Jan 22;482(4):870-876.
Title: SPOCK1 is up-regulated and promotes tumor growth via the PI3K/AKT signaling pathway in colorectal cancer.
Author: Zhang, Jiaxuan|Zhi, Xiaofei|Shi, Shiyu|Tao, Ran|Chen, Peisheng|Sun, Shiyu|Bian, Longjun|Xu, Zhangyan|Ma, Lilin
PMID: 27889608
Journal: Biomed Pharmacother. 2017 Jan;85:355-361.
Title: Silencing of long non-coding RNA SBDSP1 suppresses tumor growth and invasion in colorectal cancer.
Author: Shi, Debing|Liang, Lei|Zheng, Hongtu|Cai, Guoxiang|Li, Xinxiang|Xu, Ye|Cai, Sanjun
PMID: 27890432
Journal: Oncotarget. 2017 Jan 3;8(1):1092-1109.
Title: Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/beta-catenin signaling pathways in hepatocellular and colorectal carcinoma cells.
Author: Wang, Cong|Ruan, Ping|Zhao, Ying|Li, Xiaomin|Wang, Jun|Wu, Xiaoxiao|Liu, Tong|Wang, Shasha|Hou, Jiuzhou|Li, Wei|Li, Qian|Li, Jinghua|Dai, Fujun|Fang, Dong|Wang, Chaojie|Xie, Songqiang
PMID: 27901475
Journal: Curr Pharm Biotechnol. 2017;18(2):127-137.
Title: Erythropoietin Enhances the Cytotoxic Effect of Hydrogen Peroxide on Colon Cancer Cells.
Author: Tankiewicz-Kwedlo, Anna|Hermanowicz, Justyna M|Surazynski, Arkadiusz|Kwedlo, Wojciech|Rozkiewicz, Dariusz|Pawlak, Krystyna|Domaniewski, Tomasz|Pawlak, Dariusz
PMID: 27903235
Journal: Curr Drug Targets. 2017;18(6):734-750.
Title: Is Metformin a Therapeutic Paradigm for Colorectal Cancer: Insight into the Molecular Pathway?
Author: Thent, Zar Chi|Zaidun, Nurul Hannim|Azmi, Muhammad Fairuz|Senin, Mu Izuddin|Haslan, Haszianaliza|Salehuddin, Ruzain
PMID: 27919208
Journal: Oncotarget. 2017 Jan 10;8(2):3289-3303.
Title: Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.
Author: Zhang, Lingling|Wang, Huanan|Li, Wei|Zhong, Juchang|Yu, Rongcheng|Huang, Xinfeng|Wang, Honghui|Tan, Zhikai|Wang, Jiangang|Zhang, Yingjie
PMID: 27924057
Journal: Cell Death Differ. 2017 Mar;24(3):458-468.
Title: Ketogenesis contributes to intestinal cell differentiation.
Author: Wang, Qingding|Zhou, Yuning|Rychahou, Piotr|Fan, Teresa W-M|Lane, Andrew N|Weiss, Heidi L|Evers, B Mark
PMID: 27935584
Journal: Oncogene. 2017 May 18;36(20):2857-2867.
Title: Evolution and heterogeneity of non-hereditary colorectal cancer revealed by single-cell exome sequencing.
Author: Wu, H|Zhang, X-Y|Hu, Z|Hou, Q|Zhang, H|Li, Y|Li, S|Yue, J|Jiang, Z|Weissman, S M|Pan, X|Ju, B-G|Wu, S
PMID: 27941887
Journal: Int J Oncol. 2017 Jan;50(1):329-336.
Title: CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells.
Author: Lee, Soo Young|Kim, Kyung Ae|Kim, Chang Hyun|Kim, Young Jin|Lee, Jae-Hyuk|Kim, Hyeong Rok
PMID: 27959393
Journal: J Agric Food Chem. 2017 Jan 11;65(1):51-59.
Title: Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.
Author: Lin, Hsien-Chun|Lin, Mei-Hsiang|Liao, Jiahn-Haur|Wu, Tzu-Hua|Lee, Tzong-Huei|Mi, Fwu-Long|Wu, Chi-Hao|Chen, Ku-Chung|Cheng, Chia-Hsiung|Lin, Cheng-Wei
PMID: 27997180
Journal: Am J Pathol. 2017 Feb;187(2):377-389.
Title: cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium.
Author: Wang, Rui|Islam, Bianca N|Bridges, Allison|Sharman, Sarah K|Hu, Muhan|Hou, Yali|Somanath, Payaningal R|Venable, Laine|Singh, Nagendra|Kim, Sangmi|Sridhar, Subbaramiah|Hofmann, Franz|Browning, Darren D
PMID: 27998725
Journal: Oncotarget. 2017 Feb 7;8(6):9251-9266.
Title: LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.
Author: Vakana, Eliza|Pratt, Susan|Blosser, Wayne|Dowless, Michele|Simpson, Nicholas|Yuan, Xiu-Juan|Jaken, Susan|Manro, Jason|Stephens, Jennifer|Zhang, Youyan|Huber, Lysiane|Peng, Sheng-Bin|Stancato, Louis F
PMID: 27999210
Journal: Oncotarget. 2017 Jan 17;8(3):5003-5015.
Title: Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells.
Author: Song, Qiaoling|Sun, Xiaoxiao|Guo, Hui|Yu, Qiang
PMID: 28002807
Journal: Clin Transl Oncol. 2017 Jun;19(6):718-726.
Title: High early growth response 1 (EGR1) expression correlates with resistance to anti-EGFR treatment in vitro and with poorer outcome in metastatic colorectal cancer patients treated with cetuximab.
Author: Kumar, S S|Tomita, Y|Wrin, J|Bruhn, M|Swalling, A|Mohammed, M|Price, T J|Hardingham, J E
PMID: 28005260
Journal: Oncotarget. 2017 Jan 24;8(4):6102-6113.
Title: Idelalisib induces PUMA-dependent apoptosis in colon cancer cells.
Author: Yang, Shida|Zhu, Zhiyong|Zhang, Xiaobing|Zhang, Ning|Yao, Zhicheng
PMID: 28008149
Journal: Pathol Oncol Res. 2017 Jul;23(3):651-656.
Title: LncRNA NEAT1 Impacts Cell Proliferation and Apoptosis of Colorectal Cancer via Regulation of Akt Signaling.
Author: Peng, Wei|Wang, Zhuo|Fan, Hong
PMID: 28013491
Journal: J Biol Chem. 2017 Feb 3;292(5):1910-1924.
Title: Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy.
Author: Noguchi, Kohji|Hongama, Keita|Hariki, Shiori|Nonomiya, Yuma|Katayama, Kazuhiro|Sugimoto, Yoshikazu
PMID: 28028179
Journal: Oncotarget. 2017 Feb 7;8(6):9280-9292.
Title: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.
Author: Li, Xiangyun|Li, Mei|Ruan, Hang|Qiu, Wei|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 28030835
Journal: Oncotarget. 2017 Jan 24;8(4):6419-6432.
Title: Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells.
Author: Xiong, Li|Liu, Zhipeng|Ouyang, Guoqing|Lin, Liangwu|Huang, He|Kang, Hongxiang|Chen, Wei|Miao, Xiongying|Wen, Yu
PMID: 28031534
Journal: Oncotarget. 2017 Jan 17;8(3):4277-4288.
Title: Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Author: Bosch-Vilaro, Albert|Jacobs, Bart|Pomella, Valentina|Abbasi Asbagh, Layka|Kirkland, Richard|Michel, Joe|Singh, Sharat|Liu, Xinjun|Kim, Phillip|Weitsman, Gregory|Barber, Paul R|Vojnovic, Borivoj|Ng, Tony|Tejpar, Sabine
PMID: 28032592
Journal: Biomed Pharmacother. 2017 Mar;87:102-109.
Title: Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway.
Author: Dai, Bingling|Ma, Yujiao|Yang, Tianfeng|Wang, Wenjie|Zhang, Yanmin
PMID: 28049091
Journal: Oncotarget. 2017 Feb 7;8(6):10007-10024.
Title: The RNA-binding protein ESRP1 promotes human colorectal cancer progression.
Author: Fagoonee, Sharmila|Picco, Gabriele|Orso, Francesca|Arrigoni, Arrigo|Longo, Dario L|Forni, Marco|Scarfo, Irene|Cassenti, Adele|Piva, Roberto|Cassoni, Paola|Silengo, Lorenzo|Tolosano, Emanuela|Aime, Silvio|Taverna, Daniela|Pandolfi, Pier Paolo|Brancaccio, M
PMID: 28052020
Journal: BMC Cancer. 2017 Jan 7;17(1):33.
Title: miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway.
Author: Kuroda, Kengo|Fukuda, Tomokazu|Krstic-Demonacos, Marija|Demonacos, Constantinos|Okumura, Kazuhiko|Isogai, Hiroshi|Hayashi, Miwa|Saito, Kazuki|Isogai, Emiko
PMID: 28061765
Journal: Oncogene. 2017 Jun 1;36(22):3104-3118.
Title: Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis.
Author: Agarwal, E|Robb, C M|Smith, L M|Brattain, M G|Wang, J|Black, J D|Chowdhury, S
PMID: 28068324
Journal: Oncotarget. 2017 Feb 21;8(8):13312-13319.
Title: Poly(C)-binding protein 1 mediates drug resistance in colorectal cancer.
Author: Guo, Jiani|Zhu, Changli|Yang, Kangqun|Li, Jin|Du, Nan|Zong, Mingzhu|Zhou, Jianwei|He, Jingdong
PMID: 28076324
Journal: PLoS One. 2017 Jan 12;12(1):e0169585.
Title: AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms.
Author: Zhang, Shihu|Deng, Zhengming|Yao, Chen|Huang, Ping|Zhang, Yi|Cao, Shibing|Li, Xiangcheng
PMID: 28081222
Journal: Biosci Rep. 2017 Feb 10;37(1). pii: BSR20160432.
Title: Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.
Author: Rodgers, Samuel J|Ferguson, Daniel T|Mitchell, Christina A|Ooms, Lisa M
PMID: 28082369
Journal: Int J Oncol. 2017 Feb;50(2):736-744.
Title: Insulin induction instigates cell proliferation and metastasis in human colorectal cancer cells.
Author: Lu, Chi-Cheng|Chu, Pei-Yi|Hsia, Shih-Min|Wu, Chi-Hao|Tung, Yu-Tang|Yen, Gow-Chin
PMID: 28101572
Journal: PLoS One. 2017 Jan 20;12(1):e0170551.
Title: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.
Author: Soo, Hsien-Chuen|Chung, Felicia Fei-Lei|Lim, Kuan-Hon|Yap, Veronica Alicia|Bradshaw, Tracey D|Hii, Ling-Wei|Tan, Si-Hoey|See, Sze-Jia|Tan, Yuen-Fen|Leong, Chee-Onn|Mai, Chun-Wai
PMID: 28107519
Journal: Oncogene. 2017 Jun 15;36(24):3477-3489.
Title: The miR-487b-3p/GRM3/TGFbeta signaling axis is an important regulator of colon cancer tumorigenesis.
Author: Yi, H|Geng, L|Black, A|Talmon, G|Berim, L|Wang, J
PMID: 28114282
Journal: J Exp Clin Cancer Res. 2017 Jan 23;36(1):16.
Title: MIF/CD74 axis is a target for novel therapies in colon carcinomatosis.
Author: Bozzi, Fabio|Mogavero, Angela|Varinelli, Luca|Belfiore, Antonino|Manenti, Giacomo|Caccia, Claudio|Volpi, Chiara C|Beznoussenko, Galina V|Milione, Massimo|Leoni, Valerio|Gloghini, Annunziata|Mironov, Alexandre A|Leo, Ermanno|Pilotti, Silvana|Pierotti, Marc
PMID: 28114961
Journal: Biochem Biophys Res Commun. 2017 Mar 18;484(4):719-725.
Title: Gab3 is required for human colorectal cancer cell proliferation.
Author: Xiang, Shihao|Wang, Na|Hui, Pingping|Ma, Jiali
PMID: 28115166
Journal: Oncol Lett. 2017 Jan;13(1):342-346.
Title: Tumor necrosis factor receptor 2 promotes growth of colorectal cancer via the PI3K/AKT signaling pathway.
Author: Zhao, Tao|Li, Huihui|Liu, Zifeng
PMID: 28123565
Journal: Mol Clin Oncol. 2017 Jan;6(1):75-78.
Title: Increased serum leptin level in overweight patients with colon carcinoma: A cross-sectional and prospective study.
Author: Wang, Di|Gao, Lichen|Gong, Kuiyu|Chai, Qin|Wang, Guihua
PMID: 28123733
Journal: Saudi J Gastroenterol. 2017 Jan-Feb;23(1):34-38.
Title: Enhanced efficacy of 5-fluorouracil in combination with a dual histone deacetylase and phosphatidylinositide 3-kinase inhibitor (CUDC-907) in colorectal cancer cells.
Author: Hamam, Rimi|Ali, Dalia|Vishnubalaji, Radhakrishnan|Alsaaran, Zaid F|Chalisserry, Elna Paul|Alfayez, Musaad|Aldahmash, Abdullah|Alajez, Nehad M
PMID: 28139498
Journal: Cell Death Discov. 2017 Jan 30;3:16106.
Title: TFF3-dependent resistance of human colorectal adenocarcinoma cells HT-29/B6 to apoptosis is mediated by miR-491-5p regulation of lncRNA PRINS.
Author: Hanisch, Carlos|Sharbati, Jutta|Kutz-Lohroff, Barbara|Huber, Otmar|Einspanier, Ralf|Sharbati, Soroush
PMID: 28149533
Journal: Mol Cancer. 2017 Feb 2;16(1):33.
Title: Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.
Author: Ahmad, Rehan|Alam, Maroof|Hasegawa, Masanori|Uchida, Yasumitsu|Al-Obaid, Omar|Kharbanda, Surender|Kufe, Donald
PMID: 28153010
Journal: Cancer Prev Res (Phila). 2017 Mar;10(3):208-218.
Title: Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells.
Author: Zumwalt, Timothy J|Wodarz, Dominik|Komarova, Natalia L|Toden, Shusuke|Turner, Jacob|Cardenas, Jacob|Burn, John|Chan, Andrew T|Boland, C Richard|Goel, Ajay
PMID: 28154202
Journal: Oncotarget. 2017 Jul 25;8(30):48534-48544.
Title: Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine.
Author: Parasido, Erika Maria|Silvestri, Alessandra|Canzonieri, Vincenzo|Belluco, Claudio|Diodoro, Maria Grazia|Milione, Massimo|Melotti, Flavia|De Maria, Ruggero|Liotta, Lance|Petricoin, Emanuel F|Pierobon, Mariaelena
PMID: 28159918
Journal: Dig Dis Sci. 2017 May;62(5):1235-1245.
Title: Variable Levels of Long Noncoding RNA Expression in DNA Mismatch Repair-Proficient Early-Stage Colon Cancer.
Author: Li, Qian|Li, Nanshan|Lao, Yueqiong|Lin, Wu|Jiang, Guojun|Wei, Nan|Wang, Canghai|Liu, Kuiliang|Wu, Jing
PMID: 28160106
Journal: J Agric Food Chem. 2017 Mar 1;65(8):1566-1573.
Title: Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
Author: Chen, Xuexiang|Wu, Xian|Ouyang, Wen|Gu, Min|Gao, Zili|Song, Mingyue|Chen, Yunjiao|Lin, Yanyin|Cao, Yong|Xiao, Hang
PMID: 28169543
Journal: Cell Death Discov. 2017 Jan 23;3:16103.
Title: PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells.
Author: Xiong, Xiaopeng|Wen, Yang-An|Mitov, Mihail I|C Oaks, Mary|Miyamoto, Shigeki|Gao, Tianyan
PMID: 28179998
Journal: Free Radic Biol Med. 2017 May;106:24-37.
Title: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.
Author: Wang, Gangyang|Zhang, Tao|Sun, Wei|Wang, Hongsheng|Yin, Fei|Wang, Zhuoying|Zuo, Dongqing|Sun, Mengxiong|Zhou, Zifei|Lin, Binhui|Xu, Jing|Hua, Yingqi|Li, Haoqing|Cai, Zhengdong
PMID: 28188923
Journal: Int J Oncol. 2017 Mar;50(3):787-797.
Title: Different effect of resveratrol to induction of apoptosis depending on the type of human cancer cells.
Author: Takashina, Michinori|Inoue, Sayaka|Tomihara, Kei|Tomita, Kengo|Hattori, Kohshi|Zhao, Qing-Li|Suzuki, Tokiko|Noguchi, Makoto|Ohashi, Wakana|Hattori, Yuichi
PMID: 28197625
Journal: Int J Oncol. 2017 Mar;50(3):1011-1021.
Title: TGF-beta1/PTEN/PI3K signaling plays a critical role in the anti-proliferation effect of tetrandrine in human colon cancer cells.
Author: Chen, Qian-Zhao|Li, Yang|Shao, Ying|Zeng, Yu-Hua|Ren, Wen-Yan|Liu, Rong-Xing|Zhou, Lin-Yun|Hu, Xue-Lian|Huang, Ming|He, Fang|Sun, Wen-Juan|Wu, Ke|He, Bai-Cheng
PMID: 28197642
Journal: J Pathol Transl Med. 2017 Mar;51(2):103-121.
Title: Molecular Testing for Gastrointestinal Cancer.
Author: Lee, Hye Seung|Kim, Woo Ho|Kwak, Yoonjin|Koh, Jiwon|Bae, Jeong Mo|Kim, Kyoung-Mee|Chang, Mee Soo|Han, Hye Seung|Kim, Joon Mee|Kim, Hwal Woong|Chang, Hee Kyung|Choi, Young Hee|Park, Ji Y|Gu, Mi Jin|Lhee, Min Jin|Kim, Jung Yeon|Kim, Hee Sung|Cho, Mee-Yon
PMID: 28219002
Journal: Immunol Lett. 2017 Apr;184:7-14.
Title: Inflammatory cytokines IL-17 and TNF-alpha up-regulate PD-L1 expression in human prostate and colon cancer cells.
Author: Wang, Xun|Yang, Lingyun|Huang, Feng|Zhang, Qiuyang|Liu, Sen|Ma, Lin|You, Zongbing
PMID: 28223102
Journal: Oncotarget. 2017 Apr 4;8(14):23603-23612.
Title: The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.
Author: Zheng, Hua-Chuan|Liu, Jia-Jie|Li, Jing|Wu, Ji-Cheng|Yang, Lei|Zhao, Gui-Feng|Zhao, Xin|Jiang, Hua-Mao|Huang, Ke-Qiang|Li, Zhi-Jie
PMID: 28223542
Journal: Onco Targets Ther. 2017 Feb 13;10:811-817.
Title: AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway.
Author: Chen, Jianjun|Wang, Zhenjun|Yu, Sanshui
PMID: 28243117
Journal: Front Pharmacol. 2017 Feb 13;8:47.
Title: Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer.
Author: Baharudin, Rashidah|Ab Mutalib, Nurul-Syakima|Othman, Sri N|Sagap, Ismail|Rose, Isa M|Mohd Mokhtar, Norfilza|Jamal, Rahman
PMID: 28243201
Journal: Mol Nutr Food Res. 2017 Sep;61(9).
Title: Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colon tumorigenesis.
Author: Chou, Ya-Chun|Suh, Joon Hyuk|Wang, Yu|Pahwa, Manoj|Badmaev, Vladimir|Ho, Chi-Tang|Pan, Min-Hsiung
PMID: 28245338
Journal: Curr Pharm Des. 2017;23(27):3952-3961.
Title: Angiogenesis and Oxidative Stress in Metastatic Tumor Progression: Pathogenesis and Novel Therapeutic Approach of Colon Cancer.
Author: Auyeung, Kathy K|Ko, Joshua K
PMID: 28245762
Journal: Oncol Rep. 2017 Apr;37(4):2095-2100.
Title: CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-kappaB signaling pathway.
Author: Shen, Tao|Yang, Zhibin|Cheng, Xianshuo|Xiao, Youchuan|Yu, Kun|Cai, Xinyi|Xia, Cuifeng|Li, Yunfeng
PMID: 28259918
Journal: Mol Med Rep. 2017 Apr;15(4):2163-2173.
Title: Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
Author: Lee, Kyung Ha|Lee, Myung Sun|Cha, Eun Young|Sul, Ji Young|Lee, Jin Sun|Kim, Jin Su|Park, Jun Beom|Kim, Ji Yeon
PMID: 28260110
Journal: PLoS One. 2017 Mar 8;12(3):e0172491.
Title: Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.
Author: Weber, Lea|Al-Refae, Klaudia|Ebbert, Juliane|Jagers, Peter|Altmuller, Janine|Becker, Christian|Hahn, Stephan|Gisselmann, Gunter|Hatt, Hanns
PMID: 28273117
Journal: World J Gastroenterol. 2017 Feb 21;23(7):1171-1179.
Title: Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.
Author: Hsu, Hsi-Hsien|Chen, Ming-Cheng|Day, Cecilia Hsuan|Lin, Yueh-Min|Li, Shin-Yi|Tu, Chuan-Chou|Padma, Viswanadha Vijaya|Shih, Hui-Nung|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 28275297
Journal: J Diabetes Res. 2017;2017:3827037.
Title: Prognostic Relevance and Function of MSX2 in Colorectal Cancer.
Author: Liu, Jiancheng|An, Huaying|Yuan, Wei|Feng, Qiang|Chen, Lianzhen|Ma, Jie
PMID: 28286778
Journal: Cell Death Dis. 2017 Mar 16;8(3):e2686.
Title: PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.
Author: Tan, Xin|Chen, Shuai|Wu, Jiangxue|Lin, Jiaxin|Pan, Changchuan|Ying, Xiaofang|Pan, Zhizhong|Qiu, Lin|Liu, Ranyi|Geng, Rong|Huang, Wenlin
PMID: 28300833
Journal: Immunopharmacol Immunotoxicol. 2017 Jun;39(3):124-130.
Title: Enhancement of NK cells proliferation and function by Shikonin.
Author: Li, Yan|Lu, Hailin|Gu, Yongchun|Ning, Zhiqiang|Cao, Tinghua|Chen, Chao|Hu, Chengru|Tao, Min
PMID: 28303727
Journal: Eur J Pharmacol. 2017 Jun 15;805:67-74.
Title: Inositol hexaphosphate suppresses colorectal cancer cell proliferation via the Akt/GSK-3beta/beta-catenin signaling cascade in a 1,2-dimethylhydrazine-induced rat model.
Author: Yu, Wenyang|Liu, Cuiping|Li, Xin|Yang, Fuguo|Cheng, Lixue|Liu, Chang|Song, Yang
PMID: 28315345
Journal: J Cell Biochem. 2017 Oct;118(10):3391-3400.
Title: Tumor Suppressor PTPRJ Is a Target of miR-155 in Colorectal Cancer.
Author: Zhang, Xiao-Fei|Tu, Rongfu|Li, Keke|Ye, Pengxiang|Cui, Xiaofeng
PMID: 28316102
Journal: Biomed Pharmacother. 2017 May;89:1370-1377.
Title: Sulfatase-2 promotes the growth and metastasis of colorectal cancer by activating Akt and Erk1/2 pathways.
Author: Tao, Youmao|Han, Tao|Zhang, Tao|Sun, Caixia
PMID: 28320104
Journal: J Cell Biochem. 2017 Oct;118(10):3435-3443.
Title: STAT1 Inhibits MiR-181a Expression to Suppress Colorectal Cancer Cell Proliferation Through PTEN/Akt.
Author: Zhang, Xingwen|Li, Xiang|Tan, Fengbo|Yu, Nanhui|Pei, Haiping
PMID: 28322462
Journal: Cancer Lett. 2017 Jun 28;396:94-102.
Title: Co-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer.
Author: Koustas, Evangelos|Karamouzis, Michalis V|Mihailidou, Chrysovalantou|Schizas, Dimitrios|Papavassiliou, Athanasios G
PMID: 28323034
Journal: Sci Rep. 2017 Mar 23;7(1):372.
Title: Apigenin-induced lysosomal degradation of beta-catenin in Wnt/beta-catenin signaling.
Author: Lin, Chung-Ming|Chen, Hsin-Han|Lin, Chun-An|Wu, Hui-Chung|Sheu, Jim Jinn-Chyuan|Chen, Hui-Jye
PMID: 28337019
Journal: Int J Oncol. 2017 May;50(5):1671-1682.
Title: p53-inducible long non-coding RNA PICART1 mediates cancer cell proliferation and migration.
Author: Cao, Yu|Lin, Minglin|Bu, Yiwen|Ling, Hongyan|He, Yingchun|Huang, Chenfei|Shen, Yi|Song, Bob|Cao, Deliang
PMID: 28339031
Journal: Int J Oncol. 2017 May;50(5):1785-1791.
Title: p53/microRNA-374b/AKT1 regulates colorectal cancer cell apoptosis in response to DNA damage.
Author: Gong, Hangjun|Cao, Yu|Han, Gang|Zhang, Yun|You, Qing|Wang, Yidong|Pan, Yamin
PMID: 28339062
Journal: Endocr Relat Cancer. 2017 Jun;24(6):253-265.
Title: Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Author: Tabrizian, Tahmineh|Wang, Donghai|Guan, Fangxia|Hu, Zunju|Beck, Amanda P|Delahaye, Fabien|Huffman, Derek M
PMID: 28351943
Journal: Onco Targets Ther. 2017 Mar 14;10:1603-1611.
Title: TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling.
Author: Dai, Youyi|Duan, Huaxin|Duan, Chaojun|Zhu, Hong|Zhou, Rongrong|Pei, Haiping|Shen, Liangfang
PMID: 28352192
Journal: PLoS One. 2017 Mar 29;12(3):e0174591.
Title: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
Author: Nagappan, Arulkumar|Lee, Won Sup|Yun, Jeong Won|Lu, Jing Nan|Chang, Seong-Hwan|Jeong, Jae-Hoon|Kim, Gon Sup|Jung, Jin-Myung|Hong, Soon Chan
PMID: 28355296
Journal: Mol Cancer. 2017 Mar 29;16(1):70.
Title: Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3beta/beta-catenin pathways.
Author: Zhao, Jingkun|Ou, Baochi|Han, Dingpei|Wang, Puxiongzhi|Zong, Yaping|Zhu, Congcong|Liu, Di|Zheng, Minhua|Sun, Jing|Feng, Hao|Lu, Aiguo
PMID: 28356111
Journal: Biomed Pharmacother. 2017 Jun;90:179-186.
Title: Assessment of Olea europaea L. fruit extracts: Phytochemical characterization and anticancer pathway investigation.
Author: Maalej, Amina|Bouallagui, Zouhaier|Hadrich, Fatma|Isoda, Hiroko|Sayadi, Sami
PMID: 28360012
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2017 Mar 20;37(3):367-372.
Title: [Inhibitory effect of apatinib on HCT-116 cells and its mechanism].
Author: Yin, Liang|Wang, Jin|Huang, Feng-Chang|Zhang, Yun-Fei|Xu, Ning|Wen, Zheng-Qi|Li, Wen-Liang|Dong, Jian
PMID: 28377354
Journal: Oncotarget. 2017 Jun 13;8(24):39101-39116.
Title: A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells.
Author: Ling, Yu|Kuang, Yeye|Chen, Lin-Lin|Lao, Wei-Feng|Zhu, Yao-Ru|Wang, Le-Qi|Wang, Da
PMID: 28388571
Journal: J Agric Food Chem. 2017 May 3;65(17):3474-3480.
Title: Chemoprevention of Colorectal Cancer by Artocarpin, a Dietary Phytochemical from Artocarpus heterophyllus.
Author: Sun, Guochuan|Zheng, Zongping|Lee, Mee-Hyun|Xu, Yijuan|Kang, Soouk|Dong, Zigang|Wang, Mingfu|Gu, Zhennan|Li, Haitao|Chen, Wei
PMID: 28391699
Journal: Int J Biochem Cell Biol. 2017 Jun;87:54-68.
Title: Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy.
Author: Lin, Shengchao|Yang, Liyan|Shi, Haiyang|Du, Wenpei|Qi, Yingxue|Qiu, Cen|Liang, Xin|Shi, Weibin|Liu, Jianwen
PMID: 28392376
Journal: Hum Pathol. 2017 Jun;64:61-68.
Title: High expression of P2X7R is an independent postoperative indicator of poor prognosis in colorectal cancer.
Author: Qian, Fei|Xiao, Jianjia|Hu, Baoying|Sun, Naizhi|Yin, Wei|Zhu, Jianwei
PMID: 28412208
Journal: Oncotarget. 2017 Apr 18;8(16):26142-26153.
Title: Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells.
Author: Banerjee, Aditi|Banerjee, Vivekjyoti|Czinn, Steven|Blanchard, Thomas
PMID: 28412728
Journal: Oncotarget. 2017 Apr 18;8(16):26323-26333.
Title: Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.
Author: Wang, Linlin|Yang, Dong|Tian, Jing|Gao, Aiqin|Shen, Yihang|Ren, Xia|Li, Xia|Jiang, Guosheng|Dong, Taotao
PMID: 28412748
Journal: Toxicol Appl Pharmacol. 2017 Jul 1;326:25-33.
Title: Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy.
Author: Ji, Shuai|Tang, Shunan|Li, Kai|Li, Ziwei|Liang, Wenfei|Qiao, Xue|Wang, Qi|Yu, Siwang|Ye, Min
PMID: 28416456
Journal: Oncotarget. 2017 May 30;8(22):36266-36278.
Title: MicroRNA-22 suppresses the growth, migration and invasion of colorectal cancer cells through a Sp1 negative feedback loop.
Author: Xia, Shu-Sen|Zhang, Guang-Jun|Liu, Zuo-Liang|Tian, Hong-Peng|He, Yi|Meng, Chang-Yuan|Li, Li-Fa|Wang, Zi-Wei|Zhou, Tong
PMID: 28422727
Journal: Oncotarget. 2017 Apr 25;8(17):27929-27942.
Title: Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathway.
Author: Sun, Longci|Jiang, Chunhui|Xu, Chunjie|Xue, Hanbing|Zhou, Hong|Gu, Lei|Liu, Ye|Xu, Qing
PMID: 28427191
Journal: Biosci Rep. 2017 May 11;37(3). pii: BSR20160447.
Title: Knockdown of PRDX2 sensitizes colon cancer cells to 5-FU by suppressing the PI3K/AKT signaling pathway.
Author: Xu, Jun|Zhang, Shouru|Wang, Rong|Wu, Xingye|Zeng, Li|Fu, Zhongxue
PMID: 28432271
Journal: Carbohydr Polym. 2017 Jul 1;167:90-96.
Title: Effects of Scutellaria barbata polysaccharide on the proliferation, apoptosis and EMT of human colon cancer HT29 Cells.
Author: Sun, Pengda|Sun, Dong|Wang, Xudong
PMID: 28433181
Journal: J Cell Biol. 2017 Jun 5;216(6):1567-1577.
Title: Oncogenic beta-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids.
Author: Riemer, Pamela|Rydenfelt, Mattias|Marks, Matthias|van Eunen, Karen|Thedieck, Kathrin|Herrmann, Bernhard G|Bluthgen, Nils|Sers, Christine|Morkel, Markus
PMID: 28442534
Journal: Mol Oncol. 2017 Aug;11(8):1023-1034.
Title: Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion.
Author: Wang, Rui|Bhattacharya, Rajat|Ye, Xiangcang|Fan, Fan|Boulbes, Delphine R|Xia, Ling|Ellis, Lee M
PMID: 28453235
Journal: BMC Complement Altern Med. 2017 Apr 28;17(1):236.
Title: Apoptosis-induced effects of extract from Artemisia annua Linne by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
Author: Kim, Eun Ji|Kim, Guen Tae|Kim, Bo Min|Lim, Eun Gyeong|Kim, Sang-Yong|Kim, Young Min
PMID: 28454566
Journal: Oncotarget. 2017 Jun 20;8(25):41319-41333.
Title: TrkC promotes colorectal cancer growth and metastasis.
Author: Kim, Min Soo|Suh, Kwang Wook|Hong, Suntaek|Jin, Wook
PMID: 28455963
Journal: Int J Mol Sci. 2017 May 5;18(5). pii: ijms18050987.
Title: AF1q Mediates Tumor Progression in Colorectal Cancer by Regulating AKT Signaling.
Author: Hu, Jingwei|Li, Guodong|Liu, Liang|Wang, Yatao|Li, Xiaolan|Gong, Jianping
PMID: 28475127
Journal: Cell Death Differ. 2017 Jun;24(6):1045-1062.
Title: mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.
Author: Lampada, Aikaterini|O'Prey, James|Szabadkai, Gyorgy|Ryan, Kevin M|Hochhauser, Daniel|Salomoni, Paolo
PMID: 28475179
Journal: Int J Surg Case Rep. 2017;36:4-7.
Title: Ileocaecal and transverse colonic tuberculosis mimicking colonic malignancy - A case report.
Author: Lakhe, Prashant|Khalife, Asma|Pandya, Jayashri
PMID: 28486175
Journal: Mol Oncol. 2017 Aug;11(8):1065-1077.
Title: Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine.
Author: Baba, Yuji|Tamura, Toshiya|Satoh, Yoshihiko|Gotou, Masamitsu|Sawada, Hiroshi|Ebara, Shunsuke|Shibuya, Kazunori|Soeda, Jumpei|Nakamura, Kazuhide
PMID: 28486761
Journal: Cell Death Dis. 2017 May 11;8(5):e2789.
Title: Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer.
Author: Chen, Guo-Qing|Gong, Rui-Hong|Yang, Da-Jian|Zhang, Ge|Lu, Ai-Ping|Yan, Siu-Cheong|Lin, Shu-Hai|Bian, Zhao-Xiang
PMID: 28492544
Journal: Oncotarget. 2017 Jul 18;8(29):47619-47631.
Title: Peiminine inhibits colorectal cancer cell proliferation by inducing apoptosis and autophagy and modulating key metabolic pathways.
Author: Zheng, Zhi|Xu, Liting|Zhang, Shuofeng|Li, Wuping|Tou, Fangfang|He, Qinsi|Rao, Jun|Shen, Qiang
PMID: 28496003
Journal: Oncol Rep. 2017 Jun;37(6):3415-3422.
Title: miR-944 inhibits cell migration and invasion by targeting MACC1 in colorectal cancer.
Author: Wen, Liqiang|Li, Yingru|Jiang, Zhipeng|Zhang, Yuchao|Yang, Bin|Han, Fanghai
PMID: 28498456
Journal: Oncotarget. 2017 Jul 11;8(28):45898-45917.
Title: Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy.
Author: Kasper, Stefan|Reis, Henning|Ziegler, Sophie|Nothdurft, Silke|Mueller, Andre|Goetz, Moritz|Wiesweg, Marcel|Phasue, Jeannette|Ting, Saskia|Wieczorek, Sarah|Even, Anna|Worm, Karl|Pogorzelski, Michael|Breitenbuecher, Sandra|Meiler, Johannes|Paul, Andreas|Tra
PMID: 28507280
Journal: Cancer Res. 2017 Jul 15;77(14):3814-3822.
Title: A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer.
Author: Kloosterman, Wigard P|Coebergh van den Braak, Robert R J|Pieterse, Mark|van Roosmalen, Markus J|Sieuwerts, Anieta M|Stangl, Christina|Brunekreef, Ronne|Lalmahomed, Zarina S|Ooft, Salo|van Galen, Anne|Smid, Marcel|Lefebvre, Armel|Zwartkruis, Fried|Martens,
PMID: 28512242
Journal: Hum Gene Ther. 2017 Aug;28(8):690-700.
Title: An Oncolytic Adenovirus Expressing SNORD44 and GAS5 Exhibits Antitumor Effect in Colorectal Cancer Cells.
Author: Yuan, Sujing|Wu, Yu|Wang, Yigang|Chen, Jianhua|Chu, Liang
PMID: 28530127
Journal: Oncogenesis. 2017 May 22;6(5):e341.
Title: AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress.
Author: Rasool, R U|Nayak, D|Chakraborty, S|Faheem, M M|Rah, B|Mahajan, P|Gopinath, V|Katoch, A|Iqra, Z|Yousuf, S K|Mukherjee, D|Kumar, L D|Nargotra, A|Goswami, A
PMID: 28530706
Journal: Biomed Pharmacother. 2017 Aug;92:78-85.
Title: Isofraxidin inhibited proliferation and induced apoptosis via blockage of Akt pathway in human colorectal cancer cells.
Author: Shen, Peng|Wang, Hong-Gang|Li, Miao-Miao|Ma, Qian-Yun|Zhou, Chuan-Wen|Pan, Feng|Xie, Rui
PMID: 28531803
Journal: Oncol Rep. 2017 Jul;38(1):456-464.
Title: Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells.
Author: Zeng, Yu-Hua|Zhou, Lin-Yun|Chen, Qian-Zhao|Li, Yang|Shao, Ying|Ren, Wen-Yan|Liao, Yun-Peng|Wang, Han|Zhu, Jia-Hui|Huang, Ming|He, Fang|Wang, Jin|Wu, Ke|He, Bai-Cheng
PMID: 28534975
Journal: Oncol Rep. 2017 Jul;38(1):43-52.
Title: TRIM59 facilitates the proliferation of colorectal cancer and promotes metastasis via the PI3K/AKT pathway.
Author: Sun, Ye|Ji, Bing|Feng, Yifei|Zhang, Yue|Ji, Dongjian|Zhu, Chunyan|Wang, Sen|Zhang, Chuan|Zhang, Dongsheng|Sun, Yueming
PMID: 28534983
Journal: Biochem Biophys Res Commun. 2017 Jul 15;489(1):14-20.
Title: AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes.
Author: Wang, Hongbin|Quan, Haitian|Lou, Liguang
PMID: 28536078
Journal: Oncotarget. 2017 Jul 11;8(28):46081-46089.
Title: Killing effects of Huaier Granule combined with DC-CIK on nude mice transplanted with colon carcinoma cell line.
Author: Sun, Wen-Wen|Dou, Jin-Xia|Zhang, Lin|Qiao, Li-Kui|Shen, Na|Zhao, Qiang|Gao, Wen-Yuan
PMID: 28537906
Journal: Mol Cancer. 2017 May 26;16(1):96.
Title: MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway.
Author: Liang, Zhen|Wang, Xiao|Xu, Xin|Xie, Bo|Ji, Alin|Meng, Shuai|Li, Shiqi|Zhu, Yi|Wu, Jian|Hu, Zhenghui|Lin, Yiwei|Zheng, Xiangyi|Xie, Liping|Liu, Ben
PMID: 28549468
Journal: Am J Transl Res. 2017 May 15;9(5):2207-2218. eCollection 2017.
Title: FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma.
Author: Liu, Jia Yun|Wu, Xiao Yu|Wu, Guan Nan|Liu, Fu-Kun|Yao, Xue-Quan
PMID: 28559972
Journal: Am J Cancer Res. 2017 May 1;7(5):1227-1237. eCollection 2017.
Title: The identification and validation of Trichosstatin A as a potential inhibitor of colon tumorigenesis and colon cancer stem-like cells.
Author: Huang, Tse-Hung|Wu, Szu-Yuan|Huang, Yan-Jiun|Wei, Po-Li|Wu, Alexander Th|Chao, Tsu-Yi
PMID: 28560069
Journal: Oncol Rep. 2017 Jul;38(1):253-262.
Title: Silencing of type Igamma phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion.
Author: Cao, Siyu|Chen, Chunhua|Xue, Junli|Huang, Yan|Yang, Xiaofeng|Ling, Kun
PMID: 28560454
Journal: Oncol Rep. 2017 Jul;38(1):263-270.
Title: EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells.
Author: Cuyas, Elisabet|Queralt, Bernardo|Martin-Castillo, Begona|Bosch-Barrera, Joaquim|Menendez, Javier A
PMID: 28560458
Journal: Mol Cell Biochem. 2017 Dec;436(1-2):29-38.
Title: A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells.
Author: Song, Na|Che, Xiaofang|Xu, Lu|Qu, Jinglei|Zheng, Huachuan|Hou, Kezuo|Qu, Xiujuan|Liu, Yunpeng
PMID: 28573382
Journal: Apoptosis. 2017 Aug;22(8):988-1000.
Title: Role of a novel benzoxazine derivative in the chemosensitization of colon cancer.
Author: Suraj, Rejitha|Radhamani, Suraj|Meehan-Andrews, Terri|Bradley, Christopher
PMID: 28577196
Journal: PeerJ. 2017 May 30;5:e3394.
Title: SIX4 promotes metastasis via activation of the PI3K-AKT pathway in colorectal cancer.
Author: Li, Guodong|Hu, Fuqing|Luo, Xuelai|Hu, Junbo|Feng, Yongdong
PMID: 28584719
Journal: Biomed Pharmacother. 2017 Aug;92:696-706.
Title: Libidibia ferrea presents antiproliferative, apoptotic and antioxidant effects in a colorectal cancer cell line.
Author: Guerra, Andreza Conceicao Veras de Aguiar|Soares, Luiz Alberto Lira|Ferreira, Magda Rhayanny Assuncao|Araujo, Aurigena Antunes de|Rocha, Hugo Alexandre de Oliveira|Medeiros, Juliana Silva de|Cavalcante, Romulo Dos Santos|Junior, Raimundo Fernandes de Arau
PMID: 28586741
Journal: Int J Mol Sci. 2017 May 25;18(6). pii: ijms18061132.
Title: Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells.
Author: Hsu, Hsi-Hsien|Lin, Yueh-Min|Shen, Chia-Yao|Shibu, Marthandam Asokan|Li, Shin-Yi|Chang, Sheng-Huang|Lin, Chien-Chung|Chen, Ray-Jade|Viswanadha, Vijaya Padma|Shih, Hui-Nung|Huang, Chih-Yang
PMID: 28587064
Journal: BMC Gastroenterol. 2017 Jun 7;17(1):73.
Title: Anti-fibrogenic effect of PPAR-gamma agonists in human intestinal myofibroblasts.
Author: Koo, Jun Bon|Nam, Myeong-Ok|Jung, Younshin|Yoo, Jongman|Kim, Duk Hwan|Kim, Gwangil|Shin, Sung Jae|Lee, Kee Myung|Hahm, Ki Baik|Kim, Jong Woo|Hong, Sung Pyo|Lee, Kwang Jae|Yoo, Jun Hwan
PMID: 28592228
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Semin Cancer Biol. 2017 Oct;46:132-137.
Title: Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor.
Author: Popolo, Ada|Pinto, Aldo|Daglia, Maria|Nabavi, Seyed Fazel|Farooqi, Ammad Ahmad|Rastrelli, Luca
PMID: 28596013
Journal: J Cell Mol Med. 2017 Oct;21(10):2610-2622.
Title: Dual inhibition of BDNF/TrkB and autophagy: a promising therapeutic approach for colorectal cancer.
Author: Mazouffre, Clement|Geyl, Sophie|Perraud, Aurelie|Blondy, Sabrina|Jauberteau, Marie-Odile|Mathonnet, Muriel|Verdier, Mireille
PMID: 28597984
Journal: Cell Cycle. 2017 Jul 3;16(13):1243-1251.
Title: NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.
Author: Karki, Rajendra|Malireddi, R K Subbarao|Zhu, Qifan|Kanneganti, Thirumala-Devi
PMID: 28598238
Journal: Cell Prolif. 2017 Aug;50(4).
Title: SAV1 represses the development of human colorectal cancer by regulating the Akt-mTOR pathway in a YAP-dependent manner.
Author: Jiang, Jianwu|Chang, Wei|Fu, Yang|Gao, Yongshun|Zhao, Chunlin|Zhang, Xiefu|Zhang, Shuijun
PMID: 28618450
Journal: Oncotarget. 2017 Jul 18;8(29):47943-47956.
Title: High expression of GPR116 indicates poor survival outcome and promotes tumor progression in colorectal carcinoma.
Author: Yang, Li|Lin, Xiao-Lu|Liang, Wei|Fu, Seng-Wang|Lin, Wen-Feng|Tian, Xiao-Qing|Gao, Yun-Jie|Chen, Hao-Yan|Dai, Jun|Ge, Zhi-Zheng
PMID: 28624786
Journal: J Ethnopharmacol. 2017 Jul 31;207:19-29.
Title: 8-methoxypsoralen reduces AKT phosphorylation, induces intrinsic and extrinsic apoptotic pathways, and suppresses cell growth of SK-N-AS neuroblastoma and SW620 metastatic colon cancer cells.
Author: Bartnik, Magdalena|Slawinska-Brych, Adrianna|Zurek, Aleksandra|Kandefer-Szerszen, Martyna|Zdzisinska, Barbara
PMID: 28627461
Journal: PLoS One. 2017 Jun 22;12(6):e0179510.
Title: Bilateral blockade of MEK- and PI3K-mediated pathways downstream of mutant KRAS as a treatment approach for peritoneal mucinous malignancies.
Author: Kuracha, Murali R|Thomas, Peter|Loggie, Brian W|Govindarajan, Venkatesh
PMID: 28640835
Journal: Tumour Biol. 2017 Jun;39(6):1010428317707881.
Title: MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.
Author: Zhao, Qiujie|Xu, Lin|Sun, Xiaoyan|Zhang, Kai|Shen, Huimin|Tian, Yanan|Sun, Fengkai|Li, Yanqing
PMID: 28653875
Journal: Int J Oncol. 2017 Aug;51(2):615-624.
Title: 18 beta-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration.
Author: Wang, Saisai|Shen, Yong|Qiu, Runfeng|Chen, Zhiliang|Chen, Zhehang|Chen, Wenbin
PMID: 28656212
Journal: Integr Med Res. 2017 Jun;6(2):179-189.
Title: Induction of apoptosis by Dae-Hwang-Mok-Dan-Tang in HCT-116 colon cancer cells through activation of caspases and inactivation of the phosphatidylinositol 3-kinase/Akt signaling.
Author: Park, Cheol|Hong, Su Hyun|Choi, Yung Hyun
PMID: 28664141
Journal: Br J Cancer. 2017 Aug 8;117(4):563-571.
Title: LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression.
Author: Liao, Qing|Li, Rui|Zhou, Rui|Pan, Zhihua|Xu, Lijun|Ding, Yanqing|Zhao, Liang
PMID: 28664914
Journal: Ann Clin Lab Sci. 2017 May;47(3):264-270.
Title: HtrA1 Down-regulation Induces Cisplatin Resistance in Colon Cancer by Increasing XIAP and Activating PI3K/Akt Pathway.
Author: Xiong, Zhenfang|Fu, Zhonghua|Shi, Jun|Jiang, Xiaozhen|Wan, Hongping
PMID: 28667026
Journal: Biomed Pharmacother. 2017 Sep;93:510-521.
Title: Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis.
Author: Arun, Ashutosh|Patel, Om P S|Saini, Deepika|Yadav, Prem P|Konwar, Rituraj
PMID: 28675857
Journal: Biochem Biophys Res Commun. 2017 Sep 2;490(4):1244-1249.
Title: Feedback autophagy activation as a key resistance factor of Ku-0060648 in colorectal cancer cells.
Author: Mao, Mintao|Liu, Yumei|Gao, Xinhai
PMID: 28676397
Journal: Biochem Biophys Res Commun. 2017 Aug 26;490(3):1132-1138.
Title: Inhibition of B7-H3 reverses oxaliplatin resistance in human colorectal cancer cells.
Author: Zhang, Pengfei|Chen, Zhen|Ning, Kuan|Jin, Jian|Han, Xiaofeng
PMID: 28676400
Journal: Int J Oncol. 2017 Sep;51(3):801-811.
Title: Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/beta-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer.
Author: Xiang, Shili|Xiang, Tingxiu|Xiao, Qian|Li, Yunhai|Shao, Bianfei|Luo, Tao
PMID: 28677721
Journal: Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title: Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author: Chang, Chu-Cheng|Lin, Pei-Ching|Lin, Chun-Chi|Lan, Yuan-Tzu|Lin, Hung-Hsin|Lin, Chien-Hsing|Yang, Shung-Haur|Liang, Wen-Yi|Chen, Wei-Shone|Jiang, Jeng-Kai|Lin, Jen-Kou|Chang, Shih-Ching
PMID: 28678173
Journal: J Ethnopharmacol. 2017 Aug 17;208:72-83.
Title: Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells.
Author: Hseu, You-Cheng|Chao, Yu-Hsien|Lin, Kai-Yuan|Way, Tzong-Der|Lin, Hui-Yi|Thiyagarajan, Varadharajan|Yang, Hsin-Ling
PMID: 28688953
Journal: Oncogene. 2017 Nov 2;36(44):6132-6142.
Title: Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours.
Author: Provenzano, L|Ryan, Y|Hilton, D A|Lyons-Rimmer, J|Dave, F|Maze, E A|Adams, C L|Rigby-Jones, R|Ammoun, S|Hanemann, C O
PMID: 28692055
Journal: Oncol Lett. 2017 Jul;14(1):1097-1104.
Title: MicroRNA-215 acts as a tumor suppressor in breast cancer by targeting AKT serine/threonine kinase 1.
Author: Yao, Jian|Zhang, Ping|Li, Jin|Xu, Wei
PMID: 28693279
Journal: World J Gastroenterol. 2017 Jun 28;23(24):4341-4353.
Title: Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells.
Author: Tischlerova, Viera|Kello, Martin|Budovska, Mariana|Mojzis, Jan
PMID: 28706417
Journal: Int J Mol Sci. 2017 Jul 14;18(7). pii: ijms18071522.
Title: Pharmacogenomics of Targeted Agents for Personalization of Colorectal Cancer Treatment.
Author: Bignucolo, Alessia|De Mattia, Elena|Cecchin, Erika|Roncato, Rossana|Toffoli, Giuseppe
PMID: 28708103
Journal: Biochem Biophys Res Commun. 2017 Sep 9;491(1):209-216.
Title: Inhibition of phosphatidylinositide 3-kinase ameliorates antiproliferation by benzyl isothiocyanate in human colon cancer cells.
Author: Liu, Xiaoyang|Takano, Chiaki|Shimizu, Tomomi|Yokobe, Shintaro|Abe-Kanoh, Naomi|Zhu, Beiwei|Nakamura, Toshiyuki|Munemasa, Shintaro|Murata, Yoshiyuki|Nakamura, Yoshimasa
PMID: 28712871
Journal: Sci Rep. 2017 Jul 17;7(1):5626.
Title: The aspirin metabolite salicylate inhibits lysine acetyltransferases and MUC1 induced epithelial to mesenchymal transition.
Author: Fernandez, Harvey R|Linden, Sara K
PMID: 28717171
Journal: Cancer Invest. 2017 Aug 9;35(7):473-483.
Title: Role of GSK-3beta in Regulation of Canonical Wnt/beta-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer.
Author: Jain, Shelly|Ghanghas, Preety|Rana, Chandan|Sanyal, S N
PMID: 28718684
Journal: Mar Drugs. 2017 Jul 20;15(7). pii: md15070221.
Title: Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-kappaB Signaling.
Author: Tarhouni-Jabberi, Safa|Zakraoui, Ons|Ioannou, Efstathia|Riahi-Chebbi, Ichrak|Haoues, Meriam|Roussis, Vassilios|Kharrat, Riadh|Essafi-Benkhadir, Khadija
PMID: 28726723
Journal: Mol Cancer Ther. 2017 Oct;16(10):2223-2233.
Title: The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy.
Author: Sanderson, Michael P|Hofmann, Marco H|Garin-Chesa, Pilar|Schweifer, Norbert|Wernitznig, Andreas|Fischer, Stefan|Jeschko, Astrid|Meyer, Reiner|Moll, Jurgen|Pecina, Thomas|Arnhof, Heribert|Weyer-Czernilofsky, Ulrike|Zahn, Stephan K|Adolf, Gunther R|Kraut, N
PMID: 28729397
Journal: Sci Rep. 2017 Jul 20;7(1):5952.
Title: PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity.
Author: Arun, Raj Pranap|Sivanesan, Divya|Vidyasekar, Prasanna|Verma, Rama Shanker
PMID: 28729699
Journal: Int J Mol Med. 2017 Sep;40(3):587-606.
Title: Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 28731148
Journal: Oncol Rep. 2017 Sep;38(3):1605-1612.
Title: ANP32A modulates cell growth by regulating p38 and Akt activity in colorectal cancer.
Author: Yan, Wei|Bai, Zhun|Wang, Juan|Li, Xumei|Chi, Bixia|Chen, Xu
PMID: 28731192
Journal: Oncol Rep. 2017 Sep;38(3):1637-1644.
Title: Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
Author: Li, Siying|Yang, Guang|Zhu, Xiaosong|Cheng, Lin|Sun, Yueyue|Zhao, Zhongxi
PMID: 28737825
Journal: Biomed Pharmacother. 2017 Sep;93:1230-1237.
Title: LncRNA AB073614 regulates proliferation and metastasis of colorectal cancer cells via the PI3K/AKT signaling pathway.
Author: Wang, Yanan|Kuang, Haoyu|Xue, Jinfang|Liao, Liya|Yin, Fang|Zhou, Xiaojun
PMID: 28738539
Journal: Anticancer Res. 2017 Aug;37(8):4345-4352.
Title: miR-141 Inhibits Proliferation and Migration of Colorectal Cancer SW480 Cells.
Author: Long, Zhi H|Bai, Zhi G|Song, Jian N|Zheng, Zhi|Li, Jun|Zhang, Jun|Cai, Jun|Yao, Hong W|Wang, Jin|Yang, Ying C|Yin, Jie|Zhang, Zhong T
PMID: 28739727
Journal: Anticancer Res. 2017 Aug;37(8):4361-4369.
Title: The Axis of CXCR4/SDF-1 Plays a Role in Colon Cancer Cell Adhesion Through Regulation of the AKT and IGF1R Signalling Pathways.
Author: Zheng, Fei|Zhang, Zhongtao|Flamini, Valentina|Jiang, Wen G|Cui, Yuxin
PMID: 28739729
Journal: J Agric Food Chem. 2017 Aug 23;65(33):7200-7209.
Title: Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice.
Author: Wu, Xian|Pfalzer, Anna C|Koh, Gar Yee|Tang, Sanyuan|Crott, Jimmy W|Thomas, Michael J|Meydani, Mohsen|Mason, Joel B
PMID: 28745498
Journal: Life Sci. 2017 Sep 15;185:63-72.
Title: M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway.
Author: Peng, Ying|Qiu, Ling|Xu, Dong|Zhang, Li|Yu, Huixin|Ding, Yuedi|Deng, Lili|Lin, Jianguo
PMID: 28751160
Journal: Mol Carcinog. 2017 Dec;56(12):2669-2680.
Title: Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway.
Author: Liu, Bing|Liu, Yanfeng|Zhao, Lifen|Pan, Yue|Shan, Yujia|Li, Yang|Jia, Li
PMID: 28767179
Journal: PLoS One. 2017 Aug 2;12(8):e0180541.
Title: Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
Author: Prabhu, Varun V|Lulla, Amriti R|Madhukar, Neel S|Ralff, Marie D|Zhao, Dan|Kline, Christina Leah B|Van den Heuvel, A Pieter J|Lev, Avital|Garnett, Mathew J|McDermott, Ultan|Benes, Cyril H|Batchelor, Tracy T|Chi, Andrew S|Elemento, Olivier|Allen, Joshua E|E
PMID: 28767654
Journal: Cell Death Dis. 2017 Aug 3;8(8):e2968.
Title: miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.
Author: Liang, Leilei|Gao, Chengshun|Li, Yang|Sun, Mingming|Xu, Jingchao|Li, Huairui|Jia, Li|Zhao, Yongfu
PMID: 28771224
Journal: Cancer Sci. 2017 Oct;108(10):1985-1995.
Title: microRNA-219-5p inhibits epithelial-mesenchymal transition and metastasis of colorectal cancer by targeting lymphoid enhancer-binding factor 1.
Author: Huang, Lan-Xuan|Hu, Chun-Yan|Jing, Li|Wang, Min-Cong|Xu, Meng|Wang, Jing|Wang, Yu|Nan, Ke-Jun|Wang, Shu-Hong
PMID: 28771881
Journal: Mol Cancer Ther. 2017 Nov;16(11):2340-2350.
Title: A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Author: Galban, Stefanie|Apfelbaum, April A|Espinoza, Carlos|Heist, Kevin|Haley, Henry|Bedi, Karan|Ljungman, Mats|Galban, Craig J|Luker, Gary D|Dort, Marcian Van|Ross, Brian D
PMID: 28775144
Journal: Oncol Lett. 2017 Aug;14(2):2125-2130.
Title: Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11.
Author: Chen, Yan|Sun, Jin|Ma, Junyan
PMID: 28781653
Journal: Chem Biol Interact. 2017 Sep 25;275:162-170.
Title: Antitumor activity of beta-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways.
Author: Daaboul, Hamid E|Daher, Costantine F|Bodman-Smith, Kikki|Taleb, Robin I|Shebaby, Wassim N|Boulos, Joelle|Dagher, Carole|Mroueh, Mohamad A|El-Sibai, Mirvat
PMID: 28782499
Journal: Curr Cancer Drug Targets. 2017 Aug 8. pii: CCDT-EPUB-85166.
Title: Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.
Author: Saxena, Ashish|Tammali, Ravinder|Ramana, Kota V|Srivastava, Satish K
PMID: 28786349
Journal: Crit Rev Food Sci Nutr. 2017 Aug 11:1-13.
Title: Anthocyanins/anthocyanidins and colorectal cancer: What is behind the scenes?
Author: de Sousa Moraes, Luis Fernando|Sun, Xiaofei|Peluzio, Maria do Carmo Gouveia|Zhu, Mei-Jun
PMID: 28799785
Journal: Cancer Sci. 2017 Nov;108(11):2248-2264.
Title: Solasodine inhibits human colorectal cancer cells through suppression of the AKT/glycogen synthase kinase-3beta/beta-catenin pathway.
Author: Zhuang, Yu-Wen|Wu, Cun-En|Zhou, Jin-Yong|Chen, Xu|Wu, Jian|Jiang, Shan|Peng, Hai-Yan|Zou, Xi|Liu, Jia-Yun|Wu, Da-Peng|Gong, Tao|Qi, Ming-Hao|Xue, Tian|Liu, Shen-Lin|Cai, Hui
PMID: 28803443
Journal: Exp Ther Med. 2017 Aug;14(2):1357-1366.
Title: Dual inhibition of MET and SRC kinase activity as a combined targeting strategy for colon cancer.
Author: Song, Na|Qu, Xiujuan|Liu, Shizhou|Zhang, Simeng|Liu, Jing|Qu, Jinglei|Zheng, Huachuan|Liu, Yunpeng|Che, Xiaofang
PMID: 28810597
Journal: World J Gastroenterol. 2017 Jul 28;23(28):5167-5178.
Title: Fibroblast-derived CXCL12/SDF-1alpha promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer.
Author: Ma, Jia-Chi|Sun, Xiao-Wen|Su, He|Chen, Quan|Guo, Tian-Kang|Li, Yuan|Chen, Xiao-Chang|Guo, Jin|Gong, Zhen-Qiang|Zhao, Xiao-Dan|Qi, Jian-Bo
PMID: 28811711
Journal: J Cancer. 2017 Jul 21;8(12):2336-2345.
Title: Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance.
Author: Pi, Leiming|Zhu, Gangcai|She, Li|Wei, Ming|Liu, Guancheng|Chen, Changhan|Hu, Di|Peng, Fusen|Tan, Haolei|Liu, Yong|Huang, Donghai|Tian, Yongquan|Zhang, Xin
PMID: 28819438
Journal: J Physiol Pharmacol. 2017 Jun;68(3):375-383.
Title: The C-terminal region of the focal adhesion kinase F1 domain binds Akt1 and inhibits pressure-induced cell adhesion.
Author: Basson, M D|Zeng, B|Wang, S
PMID: 28820394
Journal: Biomed Pharmacother. 2017 Oct;94:1094-1100.
Title: Leuconostoc mesenteroides-derived anticancer pharmaceuticals hinder inflammation and cell survival in colon cancer cells by modulating NF-kappaB/AKT/PTEN/MAPK pathways.
Author: Zununi Vahed, Sepideh|Barzegari, Abolfazl|Rahbar Saadat, Yalda|Goreyshi, Ali|Omidi, Yadollah
PMID: 28821160
Journal: Cell Death Dis. 2017 Aug 24;8(8):e3019.
Title: AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells.
Author: Seiwert, Nina|Neitzel, Carina|Stroh, Svenja|Frisan, Teresa|Audebert, Marc|Toulany, Mahmoud|Kaina, Bernd|Fahrer, Jorg
PMID: 28837154
Journal: Proteomics. 2017 Dec;17(23-24).
Title: Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.
Author: Liem, Michael|Ang, Ching-Seng|Mathivanan, Suresh
PMID: 28842968
Journal: Oncol Rep. 2017 Oct;38(4):2293-2300.
Title: Scutellaria barbata D. Don inhibits 5-fluorouracil resistance in colorectal cancer by regulating PI3K/AKT pathway.
Author: Lin, Jiumao|Feng, Jianyu|Yang, Hong|Yan, Zhaokun|Li, Qiongyu|Wei, Lihui|Lai, Zijun|Jin, Yiyi|Peng, Jun
PMID: 28849113
Journal: Mol Med Rep. 2017 Oct;16(4):5592-5598.
Title: XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelialmesenchymal transition.
Author: Shen, Jiancheng|Jin, Chang'e|Liu, Yonglin|Rao, Heping|Liu, Jinrong|Li, Jie
PMID: 28849225
Journal: Anal Chem. 2017 Oct 3;89(19):10592-10600.
Title: Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors.
Author: Popp, Robert|Li, Huiyan|LeBlanc, Andre|Mohammed, Yassene|Aguilar-Mahecha, Adriana|Chambers, Andrew G|Lan, Cathy|Poetz, Oliver|Basik, Mark|Batist, Gerald|Borchers, Christoph H
PMID: 28853539
Journal: Biosystems. 2017 Dec;162:12-23.
Title: Mathematical models in cancer therapy.
Author: Jordao, Giuseppe|Tavares, Joao Nuno
PMID: 28866047
Journal: Drug Discov Ther. 2017;11(4):212-217.
Title: Sushi repeat-containing protein X-linked 2 promotes angiogenesis through the urokinase-type plasminogen activator receptor dependent integrin alphavbeta3/focal adhesion kinase pathways.
Author: Liu, Kuiliang|Fan, Jianghao|Wu, Jing
PMID: 28867754
Journal: Mar Drugs. 2017 Sep 4;15(9). pii: md15090283.
Title: Potential Application of Eicosapentaenoic Acid Monoacylglyceride in the Management of Colorectal Cancer.
Author: Morin, Caroline|Rodriguez, Enrique|Blier, Pierre U|Fortin, Samuel
PMID: 28869531
Journal: Anticancer Res. 2017 Sep;37(9):4943-4951.
Title: GRP78 Regulates Apoptosis, Cell Survival and Proliferation in 5-Fluorouracil-resistant SNUC5 Colon Cancer Cells.
Author: Lee, Jun Hee|Yoon, Yeo Min|Lee, Sang Hun
PMID: 28870916
Journal: Oncotarget. 2016 Jun 8;8(31):50476-50488.
Title: Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis.
Author: Chen, Sugong|Fisher, Robert C|Signs, Steven|Molina, L Alex|Shenoy, Anitha K|Lopez, Maria-Cecilia|Baker, Henry V|Koomen, John M|Chen, Yi|Gittleman, Haley|Barnholtz-Sloan, Jill|Berg, Annamarie|Appelman, Henry D|Huang, Emina H
PMID: 28881576
Journal: Oncotarget. 2017 Apr 18;8(32):52783-52791.
Title: Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells.
Author: Huang, Yong-Hao|Sun, Yan|Huang, Feng-Ying|Li, Yue-Nan|Wang, Cai-Chun|Mei, Wen-Li|Dai, Hao-Fu|Tan, Guang-Hong|Huang, Canhua
PMID: 28881770
Journal: Oncol Rep. 2017 Nov;38(5):2901-2910.
Title: Inositol hexaphosphate hydrolysate competitively binds to AKT to inhibit the proliferation of colon carcinoma.
Author: Chen, Chen|Yang, Fuguo|Liu, Cuiping|Cui, Lianhua|Fu, Min|Song, Yang
PMID: 28901472
Journal: Sci Rep. 2017 Sep 14;7(1):11633.
Title: Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells.
Author: Athamneh, Khawlah|Hasasna, Hussain El|Samri, Halima Al|Attoub, Samir|Arafat, Kholoud|Benhalilou, Nehla|Rashedi, Asma Al|Dhaheri, Yusra Al|AbuQamar, Synan|Eid, Ali|Iratni, Rabah
PMID: 28912474
Journal: Oncogenesis. 2017 Sep 18;6(9):e378.
Title: Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy.
Author: Woolf, N|Pearson, B E|Bondzie, P A|Meyer, R D|Lavaei, M|Belkina, A C|Chitalia, V|Rahimi, N
PMID: 28920928
Journal: J Inorg Biochem. 2017 Dec;177:27-38.
Title: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells.
Author: Dandash, Fatima|Leger, David Yannick|Fidanzi-Dugas, Chloe|Nasri, Soumaya|Bregier, Frederique|Granet, Robert|Karam, Walid|Diab-Assaf, Mona|Sol, Vincent|Liagre, Bertrand
PMID: 28923355
Journal: Oncol Lett. 2017 Sep;14(3):3741-3747.
Title: Catalpol promotes cellular apoptosis in human HCT116 colorectal cancer cells via microRNA-200 and the downregulation of PI3K-Akt signaling pathway.
Author: Liu, Lan|Gao, Hongwei|Wang, Hongbo|Zhang, Yuan|Xu, Weihua|Lin, Sen|Wang, Hongjuan|Wu, Qiong|Guo, Jianqiang
PMID: 28927141
Journal: J Cancer. 2017 Aug 22;8(14):2713-2719.
Title: The Impact of Cetuximab Plus AKT- or mTOR- Inhibitor in a Patient-Derived Colon Cancer Cell Model with Wild-Type RAS and PIK3CA Mutation.
Author: Kim, Ju Sun|Kim, Jung Eun|Kim, Kyung|Lee, Jeeyun|Park, Joon Oh|Lim, Ho Yeong|Park, Young Suk|Kang, Won Ki|Kim, Seung Tae
PMID: 28928860
Journal: Dig Dis Sci. 2017 Nov;62(11):3040-3049.
Title: MicroRNA-30a Inhibits Colorectal Cancer Metastasis Through Down-Regulation of Type I Insulin-Like Growth Factor Receptor.
Author: Liu, Y C|Park, Y R|Kim, S L|Lee, S T|Kim, S W
PMID: 28932920
Journal: Cell Oncol (Dordr). 2017 Dec;40(6):593-607.
Title: TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
Author: Das, Sarita|Nayak, Anmada|Siddharth, Sumit|Nayak, Deepika|Narayan, Satya|Kundu, Chanakya Nath
PMID: 28936683
Journal: Ann Surg Oncol. 2017 Dec;24(13):4051-4058.
Title: Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.
Author: Clarke, Callisia N|Lee, Michael S|Wei, Wei|Manyam, Ganiraju|Jiang, Zhi-Qin|Lu, Yiling|Morris, Jeffrey|Broom, Bradley|Menter, David|Vilar-Sanchez, Eduardo|Raghav, Kanwal|Eng, Cathy|Chang, George J|Simon, Iris|Bernards, Rene|Overman, Michael|Mills, Gordon B
PMID: 28936799
Journal: Tumour Biol. 2017 Sep;39(9):1010428317724517.
Title: EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Author: Alvarez, Karin|Orellana, Paulina|Villarroel, Cynthia|Contreras, Luis|Kawachi, Hiroshi|Kobayashi, Maki|Wielandt, Ana Maria|De la Fuente, Marjorie|Trivino, Juan Carlos|Kronberg, Udo|Carvallo, Pilar|Lopez-Kostner, Francisco
PMID: 28936923
Journal: Oncotarget. 2017 Apr 20;8(35):58587-58600.
Title: Targeting progastrin enhances radiosensitization of colorectal cancer cells.
Author: Kowalski-Chauvel, Aline|Gouaze-Andersson, Valerie|Vignolle-Vidoni, Alix|Delmas, Caroline|Toulas, Christine|Cohen-Jonathan-Moyal, Elizabeth|Seva, Catherine
PMID: 28938581
Journal: Clin Cancer Res. 2017 Dec 1;23(23):7340-7350.
Title: Phospholipase D1 Inhibition Linked to Upregulation of ICAT Blocks Colorectal Cancer Growth Hyperactivated by Wnt/beta-Catenin and PI3K/Akt Signaling.
Author: Kang, Dong Woo|Lee, Bo Hui|Suh, Young-Ah|Choi, Yong-Seok|Jang, Se Jin|Kim, Yong Man|Choi, Kang-Yell|Min, Do Sik
PMID: 28939743
Journal: Mol Med Rep. 2017 Nov;16(5):7864-7872.
Title: MicroRNA212 inhibits colorectal cancer cell viability and invasion by directly targeting PIK3R3.
Author: Zhang, Jian|Zhang, Yongkang|Li, Xiaoyun|Wang, Hongbo|Li, Quan|Liao, Xiaofeng
PMID: 28944887
Journal: Cancer Lett. 2017 Dec 1;410:82-91.
Title: Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1alpha pathway.
Author: Yoshikawa, Yoko|Takano, Osamu|Kato, Ichiro|Takahashi, Yoshihisa|Shima, Fumi|Kataoka, Tohru
PMID: 28951129
Journal: Cell Physiol Biochem. 2017;43(3):945-958.
Title: MicroRNA-21 (Mir-21) Promotes Cell Growth and Invasion by Repressing Tumor Suppressor PTEN in Colorectal Cancer.
Author: Wu, Yiying|Song, Yi|Xiong, Yao|Wang, Xiaodong|Xu, Ke|Han, Bin|Bai, Yang|Li, Li|Zhang, Yuanyuan|Zhou, Liming
PMID: 28957811
Journal: Molecules. 2017 Oct 3;22(10). pii: molecules22101657.
Title: Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.
Author: Kapral, Malgorzata|Wawszczyk, Joanna|Jesse, Katarzyna|Paul-Samojedny, Monika|Kusmierz, Dariusz|Weglarz, Ludmila
PMID: 28972559
Journal: Oncotarget. 2017 Jun 21;8(40):67254-67268.
Title: Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death.
Author: de Andrade Mello, Paola|Bian, Shu|Savio, Luiz Eduardo Baggio|Zhang, Haohai|Zhang, Jingping|Junger, Wolfgang|Wink, Marcia Rosangela|Lenz, Guido|Buffon, Andreia|Wu, Yan|Robson, Simon Christopher
PMID: 28978031
Journal: Oncotarget. 2017 Jun 27;8(40):67592-67604.
Title: Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation.
Author: Napolitano, Stefania|Martini, Giulia|Martinelli, Erika|Belli, Valentina|Parascandolo, Alessia|Laukkanen, Mikko O|Sforza, Vincenzo|Morgillo, Floriana|Ciardiello, Davide|Ciardiello, Fortunato|Troiani, Teresa
PMID: 28978055
Journal: Oncotarget. 2017 Aug 7;8(40):68305-68316.
Title: Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer.
Author: Belli, Valentina|Sforza, Vincenzo|Cardone, Claudia|Martinelli, Erika|Barra, Giusi|Matrone, Nunzia|Napolitano, Stefania|Morgillo, Floriana|Tuccillo, Concetta|Federico, Alessandro|Dallio, Marcello|Loguercio, Carmelina|Gravina, Antonietta Gerarda|De Palma, R
PMID: 28978118
Journal: Oncotarget. 2017 Aug 2;8(40):68696-68706.
Title: The long non-coding RNA NONHSAT062994 inhibits colorectal cancer by inactivating Akt signaling.
Author: He, Xiao-Shun|Guo, Ling-Chuan|Du, Ming-Zhan|Huang, Shan|Huang, Ren-Peng|Zhan, Sheng-Hua|Gu, Dong-Mei|Liu, Wei-Shuo|Wang, Xi-Ming|Wu, Hua|Gan, Wen-Juan
PMID: 28978149
Journal: Onco Targets Ther. 2017 Sep 11;10:4413-4422.
Title: Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer.
Author: Yang, Fei|Gao, Jun-Yi|Chen, Hua|Du, Zhen-Hua|Zhang, Xue-Qun|Gao, Wei
PMID: 28979133
Journal: Cell Death Dis. 2017 Oct 5;8(10):e3087.
Title: Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells.
Author: Wang, Sen|Wang, Kexin|Zhang, Chundong|Zhang, Wanfeng|Xu, Qian|Wang, Yitao|Zhang, Yulin|Li, Yi|Zhang, Ying|Zhu, Huifang|Song, Fangzhou|Lei, Yunlong|Bu, Youquan
PMID: 28981110
Journal: Cancer Lett. 2017 Dec 28;411:90-99.
Title: SUMOylation of IQGAP1 promotes the development of colorectal cancer.
Author: Liang, Ziwei|Yang, Yanfang|He, Yu|Yang, Pengbo|Wang, Xixi|He, Gu|Zhang, Peng|Zhu, Hongxia|Xu, Ningzhi|Zhao, Xia|Liang, Shufang
PMID: 28987385
Journal: Mol Med Rep. 2017 Dec;16(6):8747-8754.
Title: MACC1 facilitates chemoresistance and cancer stem celllike properties of colon cancer cells through the PI3K/AKT signaling pathway.
Author: Wang, Jiankai|Wang, Wenjuan|Cai, Hongyi|Du, Binbin|Zhang, Lijuan|Ma, Wen|Hu, Yongguo|Feng, Shifang|Miao, Guoying
PMID: 28990068
Journal: Nutr Cancer. 2017 Oct;69(7):1043-1052.
Title: Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Author: Terasaki, Masaru|Maeda, Hayato|Miyashita, Kazuo|Mutoh, Michihiro
PMID: 28990814
Journal: Molecules. 2017 Oct 8;22(10). pii: molecules22101670.
Title: Phaseolus acutifolius Lectin Fractions Exhibit Apoptotic Effects on Colon Cancer: Preclinical Studies Using Dimethilhydrazine or Azoxi-Methane as Cancer Induction Agents.
Author: Moreno-Celis, Ulisses|Lopez-Martinez, Josue|Blanco-Labra, Alejandro|Cervantes-Jimenez, Ricardo|Estrada-Martinez, Laura Elena|Garcia-Pascalin, Alejandro Eduardo|Guerrero-Carrillo, Maria De Jesus|Rodriguez-Mendez, Adriana Jheny|Mejia, Carmen|Ferriz-Martinez
PMID: 28991196
Journal: PLoS One. 2017 Oct 12;12(10):e0186296.
Title: Genetic variants and traits related to insulin-like growth factor-I and insulin resistance and their interaction with lifestyles on postmenopausal colorectal cancer risk.
Author: Jung, Su Yon|Rohan, Thomas|Strickler, Howard|Bea, Jennifer|Zhang, Zuo-Feng|Ho, Gloria|Crandall, Carolyn
PMID: 29023587
Journal: Dig Dis Sci. 2017 Dec;62(12):3447-3459.
Title: miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.
Author: Jia, Li|Luo, Shihua|Ren, Xiang|Li, Yang|Hu, Jialei|Liu, Bing|Zhao, Lifen|Shan, Yujia|Zhou, Huimin
PMID: 29030743
Journal: Biomed Pharmacother. 2017 Dec;96:634-641.
Title: MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer.
Author: Xu, Song|Ge, Jingping|Zhang, Zhengyu|Zhou, Wenquan
PMID: 29035829
Journal: Cancer Biomark. 2017 Dec 12;21(1):123-133.
Title: Knockdown of lncRNA CCAT2 inhibits endometrial cancer cells growth and metastasis via sponging miR-216b.
Author: Xie, Pengmu|Cao, Hongying|Li, Ying|Wang, Jianhua|Cui, Zhumei
PMID: 29036788
Journal: Mol Med Rep. 2017 Dec;16(6):9692-9700.
Title: MicroRNA760 inhibits cell proliferation and invasion of colorectal cancer by targeting the SP1mediated PTEN/AKT signalling pathway.
Author: Li, Xiaoyan|Ding, Yuansheng|Liu, Naiqing|Sun, Qinli|Zhang, Jie
PMID: 29039575
Journal: Oncol Rep. 2017 Nov;38(5):3187-3196.
Title: MicroRNA337 inhibits colorectal cancer progression by directly targeting KRAS and suppressing the AKT and ERK pathways.
Author: Liu, Xuerong|Wang, Yan|Zhao, Jinglong
PMID: 29048669
Journal: Oncotarget. 2017 Aug 24;8(42):72872-72885.
Title: Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells.
Author: Zeng, Xianliang|Chen, Sizeng|Yang, Yang|Ke, Zhao
PMID: 29069832
Journal: Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1730-1735.
Title: [Effect of resveratrol in regulating proliferation and apoptosis of rectal cancer cells via up-regulating PTEN].
Author: Lao, Ling-Juan|Song, Xin-Jiang|Xu, Jia
PMID: 29082697
Journal: Iran J Basic Med Sci. 2017 Sep;20(9):990-995.
Title: Apatinib has anti-tumor effects and induces autophagy in colon cancer cells.
Author: Lu, Wu|Ke, He|Qianshan, Ding|Zhen, Wang|Guoan, Xiang|Honggang, Yu
PMID: 29085592
Journal: Cell Biol Int. 2017 Oct 31.
Title: SODD promotes glucose uptake of colorectal cancer cells via AKT pathway.
Author: Zhang, Rui|Li, Jibin|Yan, Xiaofei|Jin, Keer|Li, Wenya|Xu, Jian|Zhao, Jian|Bai, Jinghui|Su, Xiaohui
PMID: 29087604
Journal: Pathol Oncol Res. 2017 Nov 4. pii: 10.1007/s12253-017-0347-7.
Title: Invitro Evaluation of Torin2 and 2, 6-Dihydroxyacetophenone in Colorectal Cancer Therapy.
Author: Awasthi, Ankita|Kumar, Pharvendra|Srikanth, Chittur V|Sahi, Shakti|Puria, Rekha
PMID: 29103204
Journal: J Gastrointest Cancer. 2017 Nov 7. pii: 10.1007/s12029-017-0024-9.
Title: A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer.
Author: Zhang, Tao|Ma, Yuanping|Fang, Jiansong|Liu, Chang|Chen, Liangrong
PMID: 29110225
Journal: BMC Complement Altern Med. 2017 Nov 6;17(1):486.
Title: Coix lacryma-jobi var. ma-yuen Stapf sprout extract has anti-metastatic activity in colon cancer cells in vitro.
Author: Son, Eun Suk|Kim, Young Ock|Park, Chun Geon|Park, Kyung Hun|Jeong, Sung Hwan|Park, Jeong-Woong|Kim, Se-Hee
PMID: 29110726
Journal: J Agric Food Chem. 2017 Dec 6;65(48):10464-10472.
Title: Lactoferrin Exerts Antitumor Effects by Inhibiting Angiogenesis in a HT29 Human Colon Tumor Model.
Author: Li, Hui-Ying|Li, Ming|Luo, Chao-Chao|Wang, Jia-Qi|Zheng, Nan
PMID: 29112400
Journal: Int J Mol Sci. 2017 Nov 8;18(11). pii: ijms18112363.
Title: Effect of AICAR and 5-Fluorouracil on X-ray Repair, Cross-Complementing Group 1 Expression, and Consequent Cytotoxicity Regulation in Human HCT-116 Colorectal Cancer Cells.
Author: Lee, Ko-Chao|Lin, Chien-Tsong|Chang, Shun-Fu|Chen, Cheng-Nan|Liu, Jing-Lan|Huang, Wen-Shih
PMID: 29117108
Journal: Cancer Cell Int. 2017 Oct 28;17:91.
Title: miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1.
Author: Wei, Wen-Ting|Nian, Xin-Xin|Wang, Shu-Yang|Jiao, Hong-Li|Wang, Yong-Xia|Xiao, Zhi-Yuan|Yang, Run-Wei|Ding, Yan-Qing|Ye, Ya-Ping|Liao, Wen-Ting
PMID: 29118671
Journal: Oncol Rep. 2017 Dec;38(6):3545-3553.
Title: Upregulation of miR-542-3p inhibits the growth and invasion of human colon cancer cells through PI3K/AKT/survivin signaling.
Author: Yang, Chuang|Wang, Ming-Huan|Zhou, Jun-De|Chi, Qiang
PMID: 29130099
Journal: Oncotarget. 2017 Sep 15;8(47):83052-83062.
Title: NVP-BKM120 inhibits colon cancer growth via FoxO3a-dependent PUMA induction.
Author: Yang, Shida|Li, Xin|Guan, Wenchang|Qian, Mingqin|Yao, Zhicheng|Yin, Xiaoxue|Zhao, Hongmei
PMID: 29137323
Journal: Bioorg Med Chem Lett. 2017 Dec 15;27(24):5446-5449.
Title: Novel all-hydrocarbon stapled p110alpha[E545K] peptides as blockers of the oncogenic p110alpha[E545K]-IRS1 interaction.
Author: Hu, Xiao|He, Yanhua|Wu, Liping|Hao, Yujun|Wang, Zhenghe|Zheng, Weiping
PMID: 29138025
Journal: Onco Targets Ther. 2017 Nov 3;10:5281-5288.
Title: PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells.
Author: Guo, Lingchuan|Huang, Shan|Wang, Xinwei
PMID: 29138581
Journal: Oncotarget. 2017 Aug 9;8(49):84685-84696.
Title: Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Author: Cameron, Angus J M|Veeriah, Selvaraju|Marshall, Jacqueline J T|Murray, Elizabeth R|Larijani, Banafshe|Parker, Peter J
PMID: 29156676
Journal: Braz J Med Biol Res. 2017 Nov 13;51(1):e6472.
Title: Exosomes promote cetuximab resistance via the PTEN/Akt pathway in colon cancer cells.
Author: Zhang, S|Zhang, Y|Qu, J|Che, X|Fan, Y|Hou, K|Guo, T|Deng, G|Song, N|Li, C|Wan, X|Qu, X|Liu, Y
PMID: 29160412
Journal: Oncol Lett. 2017 Dec;14(6):6379-6386.
Title: MicroRNA-497 inhibits tumor growth through targeting insulin receptor substrate 1 in colorectal cancer.
Author: Xu, Yanjie|Chen, Jianping|Gao, Cao|Zhu, Danxia|Xu, Xiaoli|Wu, Changping|Jiang, Jingting
PMID: 29163678
Journal: Cell Physiol Biochem. 2017;44(4):1370-1380.
Title: ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling.
Author: Chen, Ling|Tang, Jun|Feng, Yixiao|Li, Shuman|Xiang, Qin|He, Xiaoqian|Ren, Guosheng|Peng, Weiyan|Xiang, Tingxiu
PMID: 29186710
Journal: PLoS One. 2017 Nov 30;12(11):e0188878.
Title: Characterizing the heterogeneity of tumor tissues from spatially resolved molecular measures.
Author: Graf, John F|Zavodszky, Maria I
PMID: 29190747
Journal: Biomed Pharmacother. 2017 Dec;96:974-981.
Title: miRNA-495 suppresses proliferation and migration of colorectal cancer cells by targeting FAM83D.
Author: Yan, Likun|Yao, Jianfeng|Qiu, Jian
PMID: 29221726
Journal: Oncotarget. 2017 Aug 24;8(58):98051-98067.
Title: Inhibition of pressure-activated cancer cell adhesion by FAK-derived peptides.
Author: Zeng, Bixi|Devadoss, Dinesh|Wang, Shouye|Vomhof-DeKrey, Emilie E|Kuhn, Leslie A|Basson, Marc D
PMID: 29228673
Journal: J Pharmacol Sci. 2017 Dec;135(4):148-155.
Title: Butyrate suppresses motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner.
Author: Li, Qingran|Ding, Chujie|Meng, Tuo|Lu, Wenjie|Liu, Wenyue|Hao, Haiping|Cao, Lijuan
PMID: 29233468
Journal: Oncotarget. 2017 Sep 5;8(60):101224-101243.
Title: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Author: Golob-Schwarzl, Nicole|Schweiger, Caroline|Koller, Carina|Krassnig, Stefanie|Gogg-Kamerer, Margit|Gantenbein, Nadine|Toeglhofer, Anna M|Wodlej, Christina|Bergler, Helmut|Pertschy, Brigitte|Uranitsch, Stefan|Holter, Magdalena|El-Heliebi, Amin|Fuchs, Julia|
PMID: 29254159
Journal: Int J Mol Sci. 2017 Dec 18;18(12). pii: ijms18122748.
Title: Canadine from Corydalis turtschaninovii Stimulates Myoblast Differentiation and Protects against Myotube Atrophy.
Author: Lee, Heyjin|Lee, Sang-Jin|Bae, Gyu-Un|Baek, Nam-In|Ryu, Jae-Ha
PMID: 29258243
Journal: J Exp Clin Cancer Res. 2017 Dec 22;36(1):190.
Title: Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice.
Author: Zhang, Pan|Lai, Ze-Lin|Chen, Hui-Fen|Zhang, Min|Wang, An|Jia, Tao|Sun, Wen-Qin|Zhu, Xi-Min|Chen, Xiao-Feng|Zhao, Zheng|Zhang, Jun
PMID: 29273065
Journal: Exp Ther Med. 2017 Dec;14(6):5527-5534.
Title: Scutellaria barbata D. Don inhibits migration and invasion of colorectal cancer cells via suppression of PI3K/AKT and TGF-beta/Smad signaling pathways.
Author: Jin, Yiyi|Chen, Wujin|Yang, Hong|Yan, Zhaokun|Lai, Zijun|Feng, Jianyu|Peng, Jun|Lin, Jiumao
PMID: 29285087
Journal: Oncotarget. 2017 Nov 14;8(64):107932-107946.
Title: NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway.
Author: Sun, Kailv|Wang, Sheng|He, Jun|Xie, Yufeng|He, Yang|Wang, Zhenxin|Qin, Lei
PMID: 29296214
Journal: Front Immunol. 2017 Dec 13;8:1774.
Title: Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice.
Author: Zhang, Xuemei|Wei, Lingyu|Wang, Jing|Qin, Zailong|Wang, Jia|Lu, Yuanjun|Zheng, Xiang|Peng, Qiu|Ye, Qiurong|Ai, Feiyan|Liu, Peishan|Wang, Siwen|Li, Guiyuan|Shen, Shourong|Ma, Jian
PMID: 29326691
Journal: Oncol Lett. 2017 Dec;14(6):7923-7930.
Title: Chloroform extract of Hedyotis diffusa Willd inhibits viability of human colorectal cancer cells via suppression of AKT and ERK signaling pathways.
Author: Yan, Zhaokun|Feng, Jianyu|Peng, Jun|Lai, Zijun|Zhang, Ling|Jin, Yiyi|Yang, Hong|Chen, Wujin|Lin, Jiumao
PMID: 29344237
Journal: Oncol Lett. 2017 Dec;14(6):8197-8205.
Title: Hedyotis diffusa willd extract suppresses colorectal cancer growth through multiple cellular pathways.
Author: Feng, Jianyu|Jin, Yiyi|Peng, Jun|Wei, Lihui|Cai, Qiaoyan|Yan, Zhaokun|Lai, Zijun|Lin, Jiumao
PMID: 29344262
Journal: Oncotarget. 2017 Nov 8;8(68):112550-112564.
Title: ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.
Author: Ogawa, Tadashi|Hirohashi, Yoshihiko|Murai, Aiko|Nishidate, Toshihiko|Okita, Kenji|Wang, Liming|Ikehara, Yuzuru|Satoyoshi, Tetsuta|Usui, Akihiro|Kubo, Terufumi|Nakastugawa, Munehide|Kanaseki, Takayuki|Tsukahara, Tomohide|Kutomi, Goro|Furuhata, Tomohisa|Hir
PMID: 29348846
Journal: Gastroenterol Hepatol Bed Bench. 2017 Fall;10(4):295-302.
Title: Network analysis of common genes related to esophageal, gastric, and colon cancers.
Author: Vaseghi Maghvan, Padina|Rezaei-Tavirani, Mostafa|Zali, Hakimeh|Nikzamir, Abdolrahim|Abdi, Saeed|Khodadoostan, Mahsa|Asadzadeh-Aghdaei, Hamid
PMID: 29379595
Journal: Gastroenterol Hepatol Bed Bench. 2017 Winter;10(Suppl1):S93-S101.
Title: Common and differential genetically pathways between ulcerative colitis and colon adenocarcinoma.
Author: Akbari, Somayeh|Hosseini, Mostafa|Rezaei-Tavirani, Majid|Rezaei-Tavirani, Mostafa|Salehi, Seyed Hamid|Alemrajabi, Mahdi|Vaseghi-Maghvan, Padina|Jahani-Sherafat, Somayeh
PMID: 29511478
Journal: Gut. 2018 Feb;67(2):307-319.
Title: Identification of a fluorescent small-molecule enhancer for therapeutic autophagy in colorectal cancer by targeting mitochondrial protein translocase TIM44.
Author: Huang, Yinghui|Zhou, Jie|Luo, Shenglin|Wang, Yang|He, Jintao|Luo, Peng|Chen, Zelin|Liu, Tao|Tan, Xu|Ou, Juanjuan|Miao, Hongming|Liang, Houjie|Shi, Chunmeng
PMID: 27849558
Journal: J Cell Biochem. 2018 Mar;119(3):2460-2469.
Title: Therapeutic Potential of Targeting PI3K/AKT Pathway in Treatment of Colorectal Cancer: Rational and Progress.
Author: Bahrami, Afsane|Khazaei, Majid|Hasanzadeh, Malihe|ShahidSales, Soodabeh|Joudi Mashhad, Mona|Farazestanian, Marjaneh|Sadeghnia, Hamid Reza|Rezayi, Majid|Maftouh, Mina|Hassanian, Seyed Mahdi|Avan, Amir
PMID: 28230287
Journal: J Cell Physiol. 2018 Mar;233(3):2058-2066.
Title: Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer.
Author: Bahrami, Afsane|Hassanian, Seyed Mahdi|ShahidSales, Soodabeh|Farjami, Zahra|Hasanzadeh, Malihe|Anvari, Kazem|Aledavood, Amir|Maftouh, Mina|Ferns, Gordon A|Khazaei, Majid|Avan, Amir
PMID: 28262927
Journal: J Cell Physiol. 2018 Jan;233(1):497-505.
Title: Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC.
Author: Won, Shen-Jeu|Yen, Cheng-Hsin|Lin, Ting-Yu|Jiang-Shieh, Ya-Fen|Lin, Chun-Nan|Chen, Jyun-Ti|Su, Chun-Li
PMID: 28294332
Journal: J Ethnopharmacol. 2018 Jan 10;210:1-9.
Title: Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3beta/cyclin D1 pathway.
Author: Wang, Juan|Li, Xu-Mei|Bai, Zhun|Chi, Bi-Xia|Wei, Yan|Chen, Xu
PMID: 28684297
Journal: Nat Prod Res. 2018 Jun;32(12):1489-1492.
Title: Anticancer effect of Polyphyllin Iota in colorectal cancer cells through ROS-dependent autophagy and G2/M arrest mechanisms.
Author: Yu, Si|Wang, Lijiao|Cao, Zhixing|Gong, Daoyin|Liang, Qianyi|Chen, Hanting|Fu, Huizhu|Wang, Wenwen|Tang, Xue|Xie, Zihao|He, Yang|Peng, Cheng|Li, Yuzhi
PMID: 28714320
Journal: J Cell Mol Med. 2018 Jan;22(1):131-140.
Title: CD155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells.
Author: Zheng, Qianqian|Wang, Biao|Gao, Jian|Xin, Na|Wang, Wei|Song, Xiaowen|Shao, Yue|Zhao, Chenghai
PMID: 28816021
Journal: Mol Cell Biochem. 2018 Feb;439(1-2):199-211.
Title: Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
Author: Park, Ga Bin|Kim, Daejin
PMID: 28819788
Journal: Biomol Ther (Seoul). 2018 May 1;26(3):313-321.
Title: Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway.
Author: Lee, Jun Hee|Yun, Chul Won|Lee, Sang Hun
PMID: 28822989
Journal: Oncol Res. 2018 Mar 5;26(2):261-268.
Title: Long Noncoding RNA PlncRNA-1 Promotes Colorectal Cancer Cell Progression by Regulating the PI3K/Akt Signaling Pathway.
Author: Song, Wei|Mei, Jia-Zhuan|Zhang, Mingzhi
PMID: 28835319
Journal: J Cell Biochem. 2018 Feb;119(2):2356-2367.
Title: Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-beta/PI3K-AKT-mTOR signaling pathway.
Author: Wu, Xue-Liang|Wang, Li-Kun|Yang, Dong-Dong|Qu, Ming|Yang, Yong-Jiang|Guo, Fei|Han, Lei|Xue, Jun
PMID: 28884839
Journal: Clin Cancer Res. 2018 Jan 15;24(2):433-444.
Title: Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.
Author: Bartolome, Ruben A|Aizpurua, Carmen|Jaen, Marta|Torres, Sofia|Calvino, Eva|Imbaud, Juan I|Casal, J Ignacio
PMID: 28916526
Journal: Oncogene. 2018 Jan 25;37(4):427-438.
Title: AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.
Author: Piscitello, D|Varshney, D|Lilla, S|Vizioli, M G|Reid, C|Gorbunova, V|Seluanov, A|Gillespie, D A|Adams, P D
PMID: 28967905
Journal: Biochem Biophys Res Commun. 2018 Jan 1;495(1):539-545.
Title: Long non-coding RNA-422 acts as a tumor suppressor in colorectal cancer.
Author: Shao, Qianwen|Xu, Jing|Deng, Rong|Wei, Wei|Zhou, Bing|Yue, Chao|Zhu, Miaoling|Huang, Xingen|Zhu, Haitao
PMID: 29050940
Journal: Mol Carcinog. 2018 Feb;57(2):243-261.
Title: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Stevens, John R|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29068474
Journal: Biochem Pharmacol. 2018 Mar;149:186-204.
Title: Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation.
Author: Olah, Gabor|Modis, Katalin|Toro, Gabor|Hellmich, Mark R|Szczesny, Bartosz|Szabo, Csaba
PMID: 29074106
Journal: JAMA Oncol. 2018 Apr 1;4(4):564-568.
Title: Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.
Author: Seligmann, Jenny F|Hatch, Ace J|Richman, Susan D|Elliott, Faye|Jacobs, Bart|Brown, Sarah|Hurwitz, Herbert|Barrett, Jennifer H|Quirke, Philip|Nixon, Andrew B|Seymour, Matthew T
PMID: 29075780
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):387-397.
Title: CCR6 promotes tumor angiogenesis via the AKT/NF-kappaB/VEGF pathway in colorectal cancer.
Author: Zhu, Cong-Cong|Chen, Chun|Xu, Zhuo-Qing|Zhao, Jing-Kun|Ou, Bao-Chi|Sun, Jing|Zheng, Min-Hua|Zong, Ya-Ping|Lu, Ai-Guo
PMID: 29097259
Journal: Int J Mol Med. 2018 Jan;41(1):373-380.
Title: Herbal prescription, Danggui-Sayuk-Ga-Osuyu-Senggang-Tang, inhibits TNF-alpha-induced epithelial-mesenchymal transition in HCT116 colorectal cancer cells.
Author: Lee, Kangwook|Cho, Sung-Gook|Choi, Youn Kyung|Choi, Yu-Jeong|Lee, Gyu-Ri|Jeon, Chan-Yong|Ko, Seong-Gyu
PMID: 29115450
Journal: Mol Med Rep. 2018 Jan;17(1):358-365.
Title: Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway.
Author: Li, Qiongyu|Lai, Zijun|Yan, Zhaokun|Peng, Jun|Jin, Yiyi|Wei, Lihui|Lin, Jiumao
PMID: 29115462
Journal: Br J Pharmacol. 2018 Mar;175(5):743-762.
Title: Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer.
Author: Tankiewicz-Kwedlo, Anna|Hermanowicz, Justyna Magdalena|Domaniewski, Tomasz|Pawlak, Krystyna|Rusak, Malgorzata|Pryczynicz, Anna|Surazynski, Arkadiusz|Kaminski, Tomasz|Kazberuk, Adam|Pawlak, Dariusz
PMID: 29160911
Journal: Pharmacol Rev. 2018 Jan;70(1):1-11.
Title: RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.
Author: Yan, Chao|Theodorescu, Dan
PMID: 29196555
Journal: Mol Med Rep. 2018 Feb;17(2):2593-2599.
Title: Fibroblast activation protein-alpha in tumor cells promotes colorectal cancer angiogenesis via the Akt and ERK signaling pathways.
Author: Cao, Feng|Wang, Songsong|Wang, Huanqin|Tang, Wei
PMID: 29207091
Journal: Mol Cancer Res. 2018 Mar;16(3):543-553.
Title: TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting beta-CATENIN and AKT Signaling in Colorectal Cancer.
Author: Solberg, Nina T|Waaler, Jo|Lund, Kaja|Mygland, Line|Olsen, Petter A|Krauss, Stefan
PMID: 29222171
Journal: Int J Cancer. 2018 May 1;142(9):1853-1864.
Title: COPS5 and LASP1 synergistically interact to downregulate 14-3-3sigma expression and promote colorectal cancer progression via activating PI3K/AKT pathway.
Author: Zhou, Rui|Shao, Ziyun|Liu, Jian|Zhan, Wanqi|Gao, Qingzu|Pan, Zhihua|Wu, Ling|Xu, Lijun|Ding, Yanqing|Zhao, Liang
PMID: 29226323
Journal: Mol Med Rep. 2018 Feb;17(2):2952-2956.
Title: Insulin-like growth factor 1 inhibits autophagy of human colorectal carcinoma drug-resistant cells via the protein kinase B/mammalian target of rapamycin signaling pathway.
Author: Wang, Shuomin|Gu, Kangsheng
PMID: 29257307
Journal: Mol Med Rep. 2018 Mar;17(3):3797-3806.
Title: Hypoxia-induced Rab11-family interacting protein 4 expression promotes migration and invasion of colon cancer and correlates with poor prognosis.
Author: Wang, Jian-Zhang|Yang, Shou-Xing|Ye, Fangpeng|Xia, Xuan-Ping|Shao, Xiao-Xiao|Xia, Sheng-Long|Zheng, Bo|Xu, Chang-Long
PMID: 29257314
Journal: Dig Dis Sci. 2018 Feb;63(2):395-402.
Title: Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Author: Zhang, Shouhua|Xiao, Juhua|Chai, Yong|Hong, Zhengdong|Liu, Zhiqiang|Yuan, Rongfa|Luo, Zhipeng|Zhou, Xin|Lucero-Prisno, Don Eliseo III|Huang, Kai
PMID: 29260353
Journal: Acta Biochim Biophys Sin (Shanghai). 2018 Feb 1;50(2):156-163.
Title: Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Author: Wu, Qichao|Chen, Xiangyuan|Wang, Jiaqiang|Sun, Pengfei|Weng, Meilin|Chen, Wankun|Sun, Zhirong|Zhu, Minmin|Miao, Changhong
PMID: 29267844
Journal: Int J Cancer. 2018 May 15;142(10):2068-2079.
Title: DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-kappaB pathway in colorectal cancer.
Author: Liu, Weiying|Wang, Shixing|Sun, Qi|Yang, Zhen|Liu, Min|Tang, Hua
PMID: 29277893
Journal: Mol Cancer Ther. 2018 Jan;17(1):3-16.
Title: Rational Approaches for Combination Therapy Strategies Targeting the MAP Kinase Pathway in Solid Tumors.
Author: Tolcher, Anthony W|Peng, Wei|Calvo, Emiliano
PMID: 29295962
Journal: Med Sci Monit. 2018 Jan 7;24:149-160.
Title: Downregulation of Annexin A11 (ANXA11) Inhibits Cell Proliferation, Invasion, and Migration via the AKT/GSK-3beta Pathway in Gastric Cancer.
Author: Hua, Kelei|Li, Yong|Zhao, Qun|Fan, Liqiao|Tan, Bibo|Gu, Jianbin
PMID: 29306955
Journal: Cancer Cell Int. 2018 Jan 4;18:4.
Title: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line.
Author: Li, Jin|Wang, Yuan|Zhang, Cheng-Gong|Xiao, Hai-Juan|Hou, Jun-Ming|He, Jing-Dong
PMID: 29308053
Journal: Cancer Cell. 2018 Jan 8;33(1):125-136.e3.
Title: Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Author: Yaeger, Rona|Chatila, Walid K|Lipsyc, Marla D|Hechtman, Jaclyn F|Cercek, Andrea|Sanchez-Vega, Francisco|Jayakumaran, Gowtham|Middha, Sumit|Zehir, Ahmet|Donoghue, Mark T A|You, Daoqi|Viale, Agnes|Kemeny, Nancy|Segal, Neil H|Stadler, Zsofia K|Varghese, Anna
PMID: 29316426
Journal: Oncol Res. 2018 Jan 10.
Title: MicroRNA-511 inhibits cellular proliferation and invasion in colorectal cancer by directly targeting hepatoma-derived growth factor.
Author: He, Saifei|Wang, Guangdong|Ni, Jing|Zhuang, Juhua|Zhuang, Suiliang|Wang, Guoyu|Ye, Ying|Xia, Wei
PMID: 29321086
Journal: Oncol Rep. 2018 Mar;39(3):1387-1395.
Title: Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells.
Author: Zeng, Xianliang|Chen, Sizeng|Lin, Yanfeng|Ke, Zhao
PMID: 29328480
Journal: Oncol Rep. 2018 Mar;39(3):1516-1522.
Title: Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Author: Kim, In-Hye|Nam, Taek-Jeong
PMID: 29328495
Journal: Biomed Pharmacother. 2018 Mar;99:176-183.
Title: Schizandrin A enhances chemosensitivity of colon carcinoma cells to 5-fluorouracil through up-regulation of miR-195.
Author: Kong, Dongfang|Zhang, Deyong|Chu, Xianqun|Wang, Jing
PMID: 29331856
Journal: Invest New Drugs. 2018 Oct;36(5):743-754.
Title: Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway.
Author: Zhao, Piming|Aguilar, Ana E|Lee, Joanna Y|Paul, Lucy A|Suh, Jung H|Puri, Latika|Zhang, Meng|Beckstead, Jennifer|Witkowski, Andrzej|Ryan, Robert O|Saba, Julie D
PMID: 29335887
Journal: Biochem Biophys Res Commun. 2018 Jan 13. pii: S0006-291X(18)30067-6.
Title: TEMPORARY REMOVAL: Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway.
Author: Chang, Jian|Tang, Nan|Fang, Qi|Zhu, Kongfan|Liu, Lei|Xiong, Xingcheng|Zhu, Zhongchao|Zhang, Bixiang|Zhang, Mingzhi|Tao, Jing
PMID: 29339153
Journal: Med Sci Monit. 2018 Jan 17;24:332-341.
Title: Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor.
Author: Yang, Juanli|Zhu, Tienian|Zhao, Ruijing|Gao, Dongmei|Cui, Yujie|Wang, Kun|Guo, Yanli
PMID: 29339715
Journal: Onco Targets Ther. 2017 Dec 22;11:67-74.
Title: miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition.
Author: Ren, Haipeng|Qi, Yuanling|Yin, Xiaoyan|Gao, Jianfeng
PMID: 29339925
Journal: Br J Surg. 2018 Jan;105(2):e192-e203.
Title: Effect of Akt activation and experimental pharmacological inhibition on responses to neoadjuvant chemoradiotherapy in rectal cancer.
Author: Koyama, F C|Lopes Ramos, C M|Ledesma, F|Alves, V A F|Fernandes, J M|Vailati, B B|Sao Juliao, G P|Habr-Gama, A|Gama-Rodrigues, J|Perez, R O|Camargo, A A
PMID: 29341150
Journal: J Cancer. 2018 Jan 1;9(2):358-366.
Title: Clinical Significance of Glycoprotein Non-metastatic B and Its Association with EGFR/HER2 in Gastrointestinal Cancer.
Author: Tajima, Jesse Yu|Futamura, Manabu|Gaowa, Siqin|Mori, Ryutaro|Tanahashi, Toshiyuki|Tanaka, Yoshihiro|Matsuhashi, Nobuhisa|Takahashi, Takao|Yamaguchi, Kazuya|Miyazaki, Tatsuhiko|Yoshida, Kazuhiro
PMID: 29344282
Journal: Mol Med Rep. 2018 Mar;17(3):4203-4212.
Title: Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway.
Author: You, Shuping|Li, Weihong|Guan, Yun
PMID: 29344654
Journal: Cell Death Dis. 2018 Jan 18;9(2):25.
Title: Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling.
Author: Zhang, Xiaochao|Hu, Fayong|Li, Geng|Li, Guodong|Yang, Xi|Liu, Liang|Zhang, Rongsheng|Zhang, Bixiang|Feng, Yongdong
PMID: 29348540
Journal: Pharmacol Ther. 2018 Jun;186:138-151.
Title: CCRK is a novel signalling hub exploitable in cancer immunotherapy.
Author: Mok, Myth T|Zhou, Jingying|Tang, Wenshu|Zeng, Xuezhen|Oliver, Antony W|Ward, Simon E|Cheng, Alfred S
PMID: 29360538
Journal: Eur Rev Med Pharmacol Sci. 2018 Jan;22(1):95-100.
Title: Formyl peptide receptor 2 mediated chemotherapeutics drug resistance in colon cancer cells.
Author: Su, L-D|Peng, J-M|Ge, Y-B
PMID: 29364475
Journal: Life Sci. 2018 Mar 1;196:143-155.
Title: Does the use of melatonin overcome drug resistance in cancer chemotherapy?
Author: Asghari, Mohammad Hossein|Ghobadi, Emad|Moloudizargari, Milad|Fallah, Marjan|Abdollahi, Mohammad
PMID: 29374563
Journal: J Cell Mol Med. 2018 Apr;22(4):2430-2441.
Title: Interplay between Trx-1 and S100P promotes colorectal cancer cell epithelial-mesenchymal transition by up-regulating S100A4 through AKT activation.
Author: Zuo, Zhigui|Zhang, Peili|Lin, Feiyan|Shang, Wenjing|Bi, Ruichun|Lu, Fengying|Wu, Jianbo|Jiang, Lei
PMID: 29383839
Journal: Br J Cancer. 2018 Feb 6;118(3):353-365.
Title: Bone marrow-derived mesenchymal stromal cells promote colorectal cancer cell death under low-dose irradiation.
Author: Feng, Hao|Zhao, Jing-Kun|Schiergens, Tobias S|Wang, Pu-Xiongzhi|Ou, Bao-Chi|Al-Sayegh, Rami|Li, Ming-Lun|Lu, Ai-Guo|Yin, Shuai|Thasler, Wolfgang E
PMID: 29384527
Journal: Int J Mol Med. 2018 May;41(5):2660-2668.
Title: BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway.
Author: Gu, Yue|Li, Aifang|Sun, Hui|Li, Xueru|Zha, He|Zhao, Jiali|Xie, Jiaqing|Zeng, Zongyue|Zhou, Lan
PMID: 29393377
Journal: Oncol Res. 2018 Sep 14;26(8):1295-1305.
Title: MicroRNA-204 Inhibits the Growth and Motility of Colorectal Cancer Cells by Downregulation of CXCL8.
Author: Shuai, Feng|Wang, Bo|Dong, Shuxiao
PMID: 29402343
Journal: Hum Pathol. 2018 Apr;74:178-182.
Title: KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
Author: Tessitore, Alessandra|Bruera, Gemma|Mastroiaco, Valentina|Cannita, Katia|Cortellini, Alessio|Cocciolone, Valentina|Dal Mas, Antonella|Calvisi, Giuseppe|Zazzeroni, Francesca|Ficorella, Corrado|Ricevuto, Enrico|Alesse, Edoardo
PMID: 29409955
Journal: Sci Rep. 2018 Feb 6;8(1):2462.
Title: Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours.
Author: Das, Mrinal K|Furu, Kari|Evensen, Herman F|Haugen, Oyvind P|Haugen, Trine B
PMID: 29410498
Journal: Am J Cancer Res. 2018 Jan 1;8(1):70-80. eCollection 2018.
Title: Inhibition of Rac family protein impairs colitis and colitis-associated cancer in mice.
Author: Guo, Yandong|Xiong, Jing|Wang, Jing|Wen, Jing|Zhi, Fachao
PMID: 29416921
Journal: Oncol Lett. 2018 Jan;15(1):1236-1240.
Title: Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies.
Author: Waniczek, Dariusz|Snietura, Miroslaw|Lorenc, Zbigniew|Nowakowska-Zajdel, Ewa|Muc-Wierzgon, Malgorzata
PMID: 29422975
Journal: J Med Chem. 2018 Mar 8;61(5):1821-1832.
Title: Novel Ligustrazine-Based Analogs of Piperlongumine Potently Suppress Proliferation and Metastasis of Colorectal Cancer Cells in Vitro and in Vivo.
Author: Zou, Yu|Zhao, Di|Yan, Chang|Ji, Yanpeng|Liu, Jin|Xu, Jinyi|Lai, Yisheng|Tian, Jide|Zhang, Yihua|Huang, Zhangjian
PMID: 29424539
Journal: J Proteomics. 2018 Apr 15;177:1-10.
Title: Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model.
Author: Bucio-Noble, Daniel|Kautto, Liisa|Krisp, Christoph|Ball, Malcolm S|Molloy, Mark P
PMID: 29432917
Journal: Oncol Lett. 2018 Mar;15(3):3197-3201.
Title: mir-106a regulates cell proliferation and apoptosis of colon cancer cells through targeting the PTEN/PI3K/AKT signaling pathway.
Author: Qin, Yan|Huo, Zhibin|Song, Xiang|Chen, Xiao|Tian, Xiaopeng|Wang, Xinjie
PMID: 29435057
Journal: Oncotarget. 2017 Dec 22;9(4):4998-5015.
Title: Osteopontin-integrin engagement induces HIF-1alpha-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
Author: Fan, Chi-Shuan|Chen, Wei-Shone|Chen, Li-Li|Chen, Chia-Chi|Hsu, Yu-Ting|Chua, Kee Voon|Wang, Horng-Dar|Huang, Tze-Sing
PMID: 29435158
Journal: Mol Med Rep. 2018 Apr;17(4):5666-5675.
Title: Differential expression profiles of long noncoding RNA and mRNA in colorectal cancer tissues from patients with lung metastasis.
Author: Shu, Ruo|Xu, Yu|Tian, Yan|Zeng, Yujian|Sun, Liang|Gong, Fangyou|Lei, Yi|Wang, Kunhua|Luo, Huayou
PMID: 29436635
Journal: Cancer Med. 2018 Mar;7(3):809-819.
Title: High expression of DJ-1 promotes growth and invasion via the PTEN-AKT pathway and predicts a poor prognosis in colorectal cancer.
Author: Lin, Yong|Chen, Qian|Liu, Quan-Xing|Zhou, Dong|Lu, Xiao|Deng, Xu-Feng|Yang, Hua|Zheng, Hong|Qiu, Yuan
PMID: 29441725
Journal: Oncol Res. 2018 Sep 14;26(8):1275-1283.
Title: MicroRNA-598 Inhibits Cell Proliferation and Invasion of Glioblastoma by Directly Targeting Metastasis Associated in Colon Cancer-1 (MACC1).
Author: Wang, Ning|Zhang, Yang|Liang, Huaxin
PMID: 29444745
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1539-1551.
Title: The G protein-coupled P2Y(6) receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.
Author: Placet, Morgane|Arguin, Guillaume|Molle, Caroline M|Babeu, Jean-Philippe|Jones, Christine|Carrier, Julie C|Robaye, Bernand|Geha, Sameh|Boudreau, Francois|Gendron, Fernand-Pierre
PMID: 29454075
Journal: Gastroenterology. 2018 Jun;154(8):2209-2221.e14.
Title: P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Author: Dou, Changwei|Liu, Zhikui|Tu, Kangsheng|Zhang, Hongbin|Chen, Chen|Yaqoob, Usman|Wang, Yuanguo|Wen, Jialing|van Deursen, Jan|Sicard, Delphine|Tschumperlin, Daniel|Zou, Hongzhi|Huang, Wei-Chien|Urrutia, Raul|Shah, Vijay H|Kang, Ningling
PMID: 29454793
Journal: Exp Ther Med. 2018 Mar;15(3):2569-2574.
Title: The role of miR-766-5p in cell migration and invasion in colorectal cancer.
Author: Jia, Bin|Xia, Lei|Cao, Fang
PMID: 29456660
Journal: Oncol Lett. 2018 Mar;15(3):3904-3910.
Title: Effects of PHA-665752 and vemurafenib combination treatment on in vitro and murine xenograft growth of human colorectal cancer cells with BRAF(V600E) mutations.
Author: Zhi, Jie|Li, Zhongxin|Lv, Jian|Feng, Bo|Yang, Donghai|Xue, Liang|Zhao, Zhaolong|Zhang, Yanni|Wu, Jianhua|Jv, Yingchao|Jia, Yitao
PMID: 29456739
Journal: Circulation. 2018 Feb 19. pii: CIRCULATIONAHA.117.030816.
Title: The Failing Heart Stimulates Tumor Growth by Circulating Factors.
Author: Meijers, Wouter C|Maglione, Manuel|Bakker, Stephan J L|Oberhuber, Rupert|Kieneker, Lyanne M|de Jong, Steven|Haubner, Bernhard J|Nagengast, Wouter B|Lyon, Alexander R|van der Vegt, Bert|van Veldhuisen, Dirk J|Westenbrink, B Daan|van der Meer, Peter|Sillje,
PMID: 29459363
Journal: Mol Cancer Ther. 2018 May;17(5):943-951.
Title: Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells.
Author: Zhang, Lu|Kim, Sang Bum|Luitel, Krishna|Shay, Jerry W
PMID: 29467273
Journal: Oncol Res. 2018 Feb 22.
Title: Liquiritigenin inhibits colorectal cancer proliferation, invasion and epithelial to mesenchymal transition by decreasing expression of runt-related transcription factor 2.
Author: Meng, Fan-Chun|Lin, Jun-Kai
PMID: 29471888
Journal: Int J Med Sci. 2018 Jan 1;15(3):217-222.
Title: Association of Genetic Variants of Small Non-Coding RNAs with Survival in Colorectal Cancer.
Author: Pao, Jiunn-Bey|Lu, Te-Ling|Ting, Wen-Chien|Chen, Lu-Min|Bao, Bo-Ying
PMID: 29483812
Journal: Int J Oncol. 2018 Apr;52(4):1305-1316.
Title: Upregulation of AKAP12 with HDAC3 depletion suppresses the progression and migration of colorectal cancer.
Author: He, Ping|Li, Ke|Li, Shi-Bao|Hu, Ting-Ting|Guan, Ming|Sun, Fen-Yong|Liu, Wei-Wei
PMID: 29484387
Journal: Int J Oncol. 2018 Apr;52(4):1129-1138.
Title: Identification of candidate genes and long non-coding RNAs associated with the effect of ATP5J in colorectal cancer.
Author: Bai, Bingjun|Xie, Binbin|Pan, Zongyou|Shan, Lina|Zhao, Jianpei|Zhu, Hongbo
PMID: 29484395
Journal: Cell Prolif. 2018 Aug;51(4):e12451.
Title: Coroglaucigenin induces senescence and autophagy in colorectal cancer cells.
Author: Huang, Yong-Hao|Lei, Jing|Yi, Guo-Hui|Huang, Feng-Ying|Li, Yue-Nan|Wang, Cai-Chun|Sun, Yan|Dai, Hao-Fu|Tan, Guang-Hong
PMID: 29484762
Journal: Anticancer Res. 2018 Mar;38(3):1445-1454.
Title: AZD8055 Exerts Antitumor Effects on Colon Cancer Cells by Inhibiting mTOR and Cell-cycle Progression.
Author: Chen, Yun|Lee, Cheng-Hung|Tseng, Bor-Yuan|Tsai, Ya-Hui|Tsai, Huang-Wen|Yao, Chao-Ling|Tseng, Sheng-Hong
PMID: 29491070
Journal: Bull Cancer. 2018 Apr;105(4):336-349.
Title: Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway.
Author: Dai, Guangyao|Yao, Xiaoguang|Zhang, Yubin|Gu, Jianbin|Geng, Yunfeng|Xue, Fei|Zhang, Jingcheng
PMID: 29496262
Journal: Gene. 2018 May 20;656:30-39.
Title: Comprehensive analysis of miRNAs expression profiles revealed potential key miRNA/mRNAs regulating colorectal cancer stem cell self-renewal.
Author: Xu, Peng|Wang, Junhua|Sun, Bo|Xiao, Zhongdang
PMID: 29496555
Journal: Cancer Sci. 2018 May;109(5):1455-1467.
Title: Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Author: Akao, Yukihiro|Kumazaki, Minami|Shinohara, Haruka|Sugito, Nobuhiko|Kuranaga, Yuki|Tsujino, Takuya|Yoshikawa, Yuki|Kitade, Yukio
PMID: 29498789
Journal: J Exp Clin Cancer Res. 2018 Mar 2;37(1):41.
Title: Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway.
Author: Hu, Xiang|Li, Ya-Qi|Li, Qing-Guo|Ma, Yan-Lei|Peng, Jun-Jie|Cai, San-Jun
PMID: 29499765
Journal: Cancer Discov. 2018 May;8(5):632-647.
Title: Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.
Author: Port, Jennifer|Muthalagu, Nathiya|Raja, Meera|Ceteci, Fatih|Monteverde, Tiziana|Kruspig, Bjorn|Hedley, Ann|Kalna, Gabriela|Lilla, Sergio|Neilson, Lisa|Brucoli, Martina|Gyuraszova, Katarina|Tait-Mulder, Jacqueline|Mezna, Mokdad|Svambaryte, Silvija|Bryson,
PMID: 29500295
Journal: Am J Transl Res. 2018 Feb 15;10(2):483-490. eCollection 2018.
Title: SRPX2 regulates colon cancer cell metabolism by miR-192/215 via PI3K-Akt.
Author: Zhao, Jian|Xu, Jian|Zhang, Rui
PMID: 29511442
Journal: Am J Cancer Res. 2018 Feb 1;8(2):256-265. eCollection 2018.
Title: High expression of WWP1 predicts poor prognosis and associates with tumor progression in human colorectal cancer.
Author: Chen, Jian-Jun|Zhang, Wei
PMID: 29511596
Journal: Am J Cancer Res. 2018 Feb 1;8(2):266-279. eCollection 2018.
Title: AQP8 inhibits colorectal cancer growth and metastasis by down-regulating PI3K/AKT signaling and PCDH7 expression.
Author: Wu, De Qing|Yang, Zi Feng|Wang, Ke Jian|Feng, Xing Yu|Lv, Ze Jian|Li, Yong|Jian, Zhi Xiang
PMID: 29511597
Journal: Oncol Rep. 2018 May;39(5):2297-2305.
Title: Delineating the underlying molecular mechanisms and key genes involved in metastasis of colorectal cancer via bioinformatics analysis.
Author: Qi, Chao|Chen, Yuanlei|Zhou, Yixuan|Huang, Xucheng|Li, Guoli|Zeng, Jin|Ruan, Zhi|Xie, Xinyou|Zhang, Jun
PMID: 29517105
Journal: Med Sci Monit. 2018 Mar 9;24:1424-1433.
Title: Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Author: Liu, Shasha|Liu, Bingrong
PMID: 29519997
Journal: Mol Cancer. 2018 Mar 10;17(1):72.
Title: Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer.
Author: Tsai, Kuo-Wang|Lo, Yi-Hao|Liu, Hsuan|Yeh, Chung-Yu|Chen, You-Zuo|Hsu, Chao-Wen|Chen, Wei-Shone|Wang, Jui-Ho
PMID: 29523145
Journal: Clin Colorectal Cancer. 2018 Jun;17(2):e331-e352.
Title: Phosphorylation of p70 Ribosomal Protein S6 Kinase beta-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.
Author: Wiesweg, Marcel|Reis, Henning|Koster, Tobias|Goetz, Moritz|Worm, Karl|Herold, Thomas|Paul, Andreas|Dechene, Alexander|Schumacher, Brigitte|Markus, Peter|Virchow, Isabel|Kostbade, Karina|Wolf, Nathalie|Zaun, Gregor|Metzenmacher, Martin|Schmid, Kurt W|Schul
PMID: 29526493
Journal: World J Gastroenterol. 2018 Mar 7;24(9):1004-1012.
Title: Long noncoding RNA RP4 functions as a competing endogenous RNA through miR-7-5p sponge activity in colorectal cancer.
Author: Liu, Mu-Lin|Zhang, Qiao|Yuan, Xiao|Jin, Long|Wang, Li-Li|Fang, Tao-Tao|Wang, Wen-Bin
PMID: 29531464
Journal: Oncol Lett. 2018 Apr;15(4):4463-4470.
Title: Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.
Author: Han, Chengzheng|Xing, Guozheng|Zhang, Mengying|Zhong, Min|Han, Zhen|He, Chiyi|Liu, Xiaoping
PMID: 29541215
Journal: Oncol Lett. 2018 Apr;15(4):5465-5472.
Title: Expression of factors and key components associated with the PI3K signaling pathway in colon cancer.
Author: Chen, Hua|Gao, Junyi|Du, Zhenhua|Zhang, Xuequn|Yang, Fei|Gao, Wei
PMID: 29552187
Journal: Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):168-173.
Title: [Killing effect of Huaier combined with DC-CIK on nude mice bearing colon cancer HT29 stem cells in vivo].
Author: Sun, Wen-Wen|Dou, Jin-Xia|Zhang, Lin|Qiao, Li-Kui|Shen, Na|Gao, Wen-Yuan
PMID: 29552828
Journal: Anticancer Drugs. 2018 Jul;29(6):530-538.
Title: Celastrol inhibits colorectal cancer cell proliferation and migration through suppression of MMP3 and MMP7 by the PI3K/AKT signaling pathway.
Author: Bufu, Tang|Di, Xu|Yilin, Zhao|Gege, Liang|Xi, Chen|Ling, Wang
PMID: 29553945
Journal: RNA Biol. 2018;15(6):773-786.
Title: Codon misreading tRNAs promote tumor growth in mice.
Author: Santos, Mafalda|Pereira, Patricia M|Varanda, A Sofia|Carvalho, Joana|Azevedo, Mafalda|Mateus, Denisa D|Mendes, Nuno|Oliveira, Patricia|Trindade, Fabio|Pinto, Marta Teixeira|Bordeira-Carrico, Renata|Carneiro, Fatima|Vitorino, Rui|Oliveira, Carla|Santos, Ma
PMID: 29558247
Journal: J Cancer Res Clin Oncol. 2018 Jun;144(6):1049-1063.
Title: Cartilage oligomeric matrix protein is a prognostic factor and biomarker of colon cancer and promotes cell proliferation by activating the Akt pathway.
Author: Liu, Ting-Ting|Liu, Xi-Sheng|Zhang, Meng|Liu, Xue-Ni|Zhu, Fu-Xiang|Zhu, Fang-Ming|Ouyang, Si-Wen|Li, Shan-Bao|Song, Chen-Long|Sun, Hui-Min|Lu, Su|Zhang, Yu|Lin, Jun|Tang, Hua-Mei|Peng, Zhi-Hai
PMID: 29560517
Journal: Oncotarget. 2017 Dec 8;9(17):13167-13180.
Title: Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells.
Author: Chen, Hsin-Pao|Lee, Yung-Kuo|Huang, Shih Yin|Shi, Pei-Chun|Hsu, Ping-Chi|Chang, Chuan-Fa
PMID: 29568348
Journal: Cell Biochem Funct. 2018 Apr;36(3):116-128.
Title: Deciphering the molecular mechanism and apoptosis underlying the in-vitro and in-vivo chemotherapeutic efficacy of vanadium luteolin complex in colon cancer.
Author: Roy, Souvik|Chakraborty, Tania
PMID: 29574863
Journal: J Cell Physiol. 2018 Sep;233(9):7134-7142.
Title: Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo.
Author: Jeng, Long-Bin|Kumar Velmurugan, Bharath|Chen, Ming-Cheng|Hsu, Hsi-Hsien|Ho, Tsung-Jung|Day, Cecilia-Hsuan|Lin, Yueh-Min|Padma, V Vijaya|Tu, Chuan-Chou|Huang, Chih-Yang
PMID: 29574877
Journal: Exp Ther Med. 2018 Apr;15(4):3751-3758.
Title: Reverting doxorubicin resistance in colon cancer by targeting a key signaling protein, steroid receptor coactivator.
Author: Xiong, Sang|Xiao, Gong-Wei
PMID: 29581735
Journal: Oncotarget. 2018 Feb 16;9(18):14306-14310.
Title: TP53 mutations and number of alterations correlate with maximum standardized uptake value (SUVmax) determined by positron emission tomography/computed tomography (PET/CT) [(18)F] fluorodeoxyglucose ((18)F-FDG PET).
Author: Chang, Geraldine H|Kurzrock, Razelle|Tran, Lisa|Schwaederle, Maria|Hoh, Carl K
PMID: 29581845
Journal: Evid Based Complement Alternat Med. 2018 Feb 12;2018:6517034.
Title: A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.
Author: Liu, Xinkui|Wu, Jiarui|Zhang, Dan|Wang, Kaihuan|Duan, Xiaojiao|Zhang, Xiaomeng
PMID: 29619072
Journal: Mol Med Rep. 2018 Jun;17(6):7721-7729.
Title: Formononetin inhibits colon carcinoma cell growth and invasion by microRNA149mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.
Author: Wang, Ai-Lei|Li, Yong|Zhao, Qun|Fan, Li-Qiao
PMID: 29620230
Journal: Int J Oncol. 2018 Jun;52(6):2031-2040.
Title: p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells.
Author: Chowchaikong, Nittiya|Nilwarangkoon, Sirinun|Laphookhieo, Surat|Tanunyutthawongse, Chantra|Watanapokasin, Ramida
PMID: 29620273
Journal: Int J Biol Macromol. 2018 Jul 15;114:1127-1133.
Title: Anti-colon-cancer effects of polysaccharides: A mini-review of the mechanisms.
Author: Ji, Xiaolong|Peng, Qiang|Wang, Min
PMID: 29627471
Journal: Am J Cancer Res. 2018 Mar 1;8(3):435-449. eCollection 2018.
Title: microRNA-532 suppresses the PI3K/Akt signaling pathway to inhibit colorectal cancer progression by directly targeting IGF-1R.
Author: Song, Ying|Zhao, Yue|Ding, Xiangfu|Wang, Xiaodong
PMID: 29636999
Journal: Food Funct. 2018 Apr 25;9(4):2145-2157.
Title: The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle.
Author: Afrin, Sadia|Giampieri, Francesca|Gasparrini, Massimiliano|Forbes-Hernandez, Tamara Y|Cianciosi, Danila|Reboredo-Rodriguez, Patricia|Amici, Adolfo|Quiles, Jose L|Battino, Maurizio
PMID: 29645049
Journal: Phytomedicine. 2018 Mar 15;42:164-171.
Title: Pristimerin, a naturally occurring triterpenoid, attenuates tumorigenesis in experimental colitis-associated colon cancer.
Author: Park, Ju-Hyung|Kim, Jin-Kyung
PMID: 29655682
Journal: Oncogene. 2018 Jul;37(28):3852-3863.
Title: AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.
Author: Coant, Nicolas|Garcia-Barros, Monica|Zhang, Qifeng|Obeid, Lina M|Hannun, Yusuf A
PMID: 29662189
Journal: Cancer Res. 2018 Jun 15;78(12):3163-3175.
Title: Deptor Is a Novel Target of Wnt/beta-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.
Author: Wang, Qingding|Zhou, Yuning|Rychahou, Piotr|Harris, Jennifer W|Zaytseva, Yekaterina Y|Liu, Jinpeng|Wang, Chi|Weiss, Heidi L|Liu, Chunming|Lee, Eun Y|Evers, B Mark
PMID: 29666061
Journal: Mol Carcinog. 2018 Aug;57(8):1055-1066.
Title: Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells.
Author: Wu, Wei|Karelia, Deepkamal|Pramanik, Kartick|Amin, Shantu G|Sharma, Arun K|Jiang, Cheng|Lu, Junxuan
PMID: 29668110
Journal: Mol Cancer Res. 2018 Jul;16(7):1077-1091.
Title: Crosstalk Between Apoptosis and Autophagy Is Regulated by the Arginylated BiP/Beclin-1/p62 Complex.
Author: Song, Xinxin|Lee, Dae-Hee|Dilly, Ashok-Kumar|Lee, Young-Sun|Choudry, Haroon Asif|Kwon, Yong Tae|Bartlett, David L|Lee, Yong J
PMID: 29669822
Journal: J Cancer. 2018 Mar 14;9(7):1207-1217.
Title: Synergistic antitumor effects of cMet inhibitor in combination with anti-VEGF in colorectal cancer patient-derived xenograft models.
Author: Chen, Xiangheng|Guan, Zhonghai|Lu, Jun|Wang, Haohao|Zuo, Zhongkun|Ye, Fei|Huang, Jiangsheng|Teng, Lisong
PMID: 29675102
Journal: Biomed Pharmacother. 2018 Jul;103:729-737.
Title: Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells.
Author: Mou, Jing-Jing|Peng, Jin|Shi, Ying-Ying|Li, Na|Wang, You|Ke, Yuan|Zhou, Yun-Feng|Zhou, Fu-Xiang
PMID: 29684851
Journal: Int Immunopharmacol. 2018 Jun;59:375-383.
Title: Toll-like receptor 2 stimulation promotes colorectal cancer cell growth via PI3K/Akt and NF-kappaB signaling pathways.
Author: Liu, You Dong|Ji, Cheng Bo|Li, Shan Bao|Yan, Feng|Gu, Qi Sheng|Balic, Jesse J|Yu, Liang|Li, Ji Kun
PMID: 29689497
Journal: Int J Mol Med. 2018 Jul;42(1):625-632.
Title: Downregulation of Lgr6 inhibits proliferation and invasion and increases apoptosis in human colorectal cancer.
Author: Wang, Fei|Dai, Chun-Qian|Zhang, Li-Rong|Bing, Cao|Qin, Jun|Liu, Yi-Fei
PMID: 29693156
Journal: Int J Cancer. 2018 Apr 26.
Title: Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.
Author: Koh, Gar Yee|Kane, Anne|Lee, Kyongbum|Xu, Qiaobing|Wu, Xian|Roper, Jatin|Mason, Joel B|Crott, Jimmy W
PMID: 29696632
Journal: Theranostics. 2018 Mar 7;8(8):2094-2106.
Title: Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy.
Author: Feng, Junnan|Zhao, Chuanke|Wang, Lixin|Qu, Like|Zhu, Hua|Yang, Zhi|An, Guo|Tian, Huifang|Shou, Chengchao
PMID: 29721065
Journal: Nutrients. 2018 May 1;10(5). pii: nu10050560.
Title: Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells.
Author: Attoub, Samir|Arafat, Kholoud|Khalaf, Tamam|Sulaiman, Shahrazad|Iratni, Rabah
PMID: 29724012
Journal: Oncol Lett. 2018 May;15(5):7243-7248.
Title: miR-486-5p regulates the migration and invasion of colorectal cancer cells through targeting PIK3R1.
Author: Zhang, Yuhao|Fu, Jun|Zhang, Zhijin|Qin, Huanlong
PMID: 29725442
Journal: Oncotarget. 2018 Apr 13;9(28):19911-19928.
Title: Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells.
Author: Kim, Eun-Ji|Kang, Gyeoung-Jin|Kang, Jung-Il|Boo, Hye-Jin|Hyun, Jin Won|Koh, Young Sang|Chang, Weon-Young|Kim, Young Ree|Kwon, Jung-Mi|Maeng, Young Hee|Yoo, Eun-Sook|Lee, Chang Hoon|Kang, Hee-Kyoung
PMID: 29731993
Journal: J Cell Biochem. 2018 Aug;119(8):6943-6952.
Title: Metformin increases the cytotoxicity of oxaliplatin in human DLD-1 colorectal cancer cells through down-regulating HMGB1 expression.
Author: Huang, Wen-Shih|Lin, Chien-Tsong|Chen, Cheng-Nan|Chang, Shun-Fu|Chang, Hsin-I|Lee, Ko-Chao
PMID: 29737584
Journal: Sci Rep. 2018 May 8;8(1):7238.
Title: Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology.
Author: Zhu, Hongxu|Hao, Jian|Niu, Yangyang|Liu, Dan|Chen, Dan|Wu, Xiongzhi
PMID: 29740162
Journal: J BUON. 2018 Mar-Apr;23(2):340-345.
Title: Boswellic acid exerts potent anticancer effects in HCT-116 human colon cancer cells mediated via induction of apoptosis, cell cycle arrest, cell migration inhibition and inhibition of PI3K/AKT signalling pathway.
Author: Wang, Dan|Ge, Shuke|Bai, Jichang|Song, Yongwei
PMID: 29745074
Journal: Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title: Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
Author: D'Haene, Nicky|Fontanges, Quitterie|De Neve, Nancy|Blanchard, Oriane|Melendez, Barbara|Delos, Monique|Dehou, Marie-Francoise|Maris, Calliope|Nagy, Nathalie|Rousseau, Emmanuel|Vandenhove, Josse|Gilles, Andre|De Prez, Carine|Verset, Laurine|Van Craynest, Ma
PMID: 29755687
Journal: Int J Cancer. 2018 Oct 15;143(8):1963-1977.
Title: Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells.
Author: Abdul-Wahid, Aws|Cydzik, Marzena|Fischer, Nicholas W|Prodeus, Aaron|Shively, John E|Martel, Anne|Alminawi, Samira|Ghorab, Zeina|Berinstein, Neil L|Gariepy, Jean
PMID: 29756328
Journal: J Cell Biochem. 2018 Sep;119(9):7256-7263.
Title: Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A.
Author: Zhang, Rui|Xu, Jian|Zhao, Jian|Bai, Jing H
PMID: 29761838
Journal: Int J Oncol. 2018 Aug;53(2):620-632.
Title: TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer.
Author: Zhang, Yue|Feng, Yifei|Ji, Dongjian|Wang, Qingyuan|Qian, Wenwei|Wang, Shijia|Zhang, Zhiyuan|Ji, Bing|Zhang, Chuan|Sun, Yueming|Fu, Zan
PMID: 29767249
Journal: Cell Physiol Biochem. 2018;47(1):356-367.
Title: Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3sigma.
Author: Wang, Pu|Lu, Yu Cheng|Wang, Jie|Wang, Lan|Yu, Hanry|Li, Yuan Fei|Kong, Alice|Chan, Juliana|Lee, Shaochin
PMID: 29768267
Journal: PLoS One. 2018 May 17;13(5):e0197563.
Title: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol.
Author: Wang, Jingqiu|Fang, Xianying|Ge, Lin|Cao, Fuliang|Zhao, Linguo|Wang, Zhenzhong|Xiao, Wei
PMID: 29771951
Journal: Apoptosis. 2018 Jun;23(5-6):356-374.
Title: Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer.
Author: Li, Sanhong|Tian, Jilai|Zhang, Hongming|Zhou, Shoubing|Wang, Xiyong|Zhang, Lei|Yang, Jiapeng|Zhang, Zhigang|Ji, Zhenling
PMID: 29777330
Journal: Oncol Rep. 2018 Jul;40(1):554-564.
Title: MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2.
Author: Li, Jibin|Xu, Jian|Yan, Xiaofei|Jin, Keer|Li, Wenya|Zhang, Rui
PMID: 29781037
Journal: Int J Mol Sci. 2018 May 22;19(5). pii: ijms19051541.
Title: SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma.
Author: Shen, Ping|Yang, Shu|Sun, Haimei|Li, Guilan|Wu, Bo|Ji, Fengqing|Sun, Tingyi|Zhou, Deshan
PMID: 29786668
Journal: Braz J Med Biol Res. 2018;51(6):e7046.
Title: lncRNA CCAT1 promotes cell proliferation, migration, and invasion by down-regulation of miR-143 in FTC-133 thyroid carcinoma cell line.
Author: Yang, Tianzheng|Zhai, Hongyan|Yan, Ruihong|Zhou, Zhenhu|Gao, Lei|Wang, Luqing
PMID: 29791590
Journal: Clin Epigenetics. 2018 May 23;10:69.
Title: Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer.
Author: Yan, Wenji|Wu, Kongming|Herman, James G|Xu, Xiuduan|Yang, Yunsheng|Dai, Guanghai|Guo, Mingzhou
PMID: 29796120
Journal: Oncol Lett. 2018 Jun;15(6):8223-8230.
Title: Asiatic acid inhibits proliferation, migration and induces apoptosis by regulating Pdcd4 via the PI3K/Akt/mTOR/p70S6K signaling pathway in human colon carcinoma cells.
Author: Hao, Yajuan|Huang, Jiawei|Ma, Yun|Chen, Wancheng|Fan, Qin|Sun, Xuegang|Shao, Meng|Cai, Hongbing
PMID: 29805556
Journal: Technol Cancer Res Treat. 2018 Jan 1;17:1533034618775509.
Title: MiR-199a-5p Inhibits the Growth and Metastasis of Colorectal Cancer Cells by Targeting ROCK1.
Author: Zhu, Qian Dong|Zhou, Qing Qing|Dong, Lemei|Huang, Zhiming|Wu, Fang|Deng, Xia
PMID: 29807462
Journal: Cell Death Dis. 2018 May 29;9(6):640.
Title: miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP.
Author: Choe, Min Ho|Yoon, Yina|Kim, Joon|Hwang, Sang-Gu|Han, Young-Hoon|Kim, Jae-Sung
PMID: 29844307
Journal: Oncol Rep. 2018 Aug;40(2):813-822.
Title: shRNAinduced knockdown of the SPERT gene inhibits proliferation and promotes apoptosis of human colorectal cancer RKO cells.
Author: Zheng, Long-Zhi|Chen, Si-Zeng
PMID: 29845259
Journal: Oncol Rep. 2018 Aug;40(2):1083-1092.
Title: Dual mTOR/PI3K inhibitor NVPBEZ235 arrests colorectal cancer cell growth and displays differential inhibition of 4EBP1.
Author: Alqurashi, Naif|Hashimi, Saeed M|Alowaidi, Faisal|Ivanovski, Saso|Wei, Ming Q
PMID: 29845289
Journal: Med Sci Monit. 2018 Jun 3;24:3710-3719.
Title: Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells.
Author: Meng, Ling-Qi|Wang, Yue|Luo, Ying-Hua|Piao, Xian-Ji|Liu, Chang|Wang, Yue|Zhang, Yi|Wang, Jia-Ru|Wang, Hao|Xu, Wan-Ting|Liu, Yang|Wu, Yi-Qin|Sun, Hu-Nan|Han, Ying-Hao|Jin, Mei-Hua|Shen, Gui-Nan|Fang, Nan-Zhu|Jin, Cheng-Hao
PMID: 29860266
Journal: Cell Death Dis. 2018 Jun 4;9(6):673.
Title: Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
Author: Pan, Shengli|Deng, Yingying|Fu, Jun|Zhang, Yuhao|Zhang, Zhijin|Ru, Xiaokun|Qin, Xianju
PMID: 29867200
Journal: Oncotarget. 2018 May 15;9(37):24787-24800.
Title: Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.
Author: Zaytseva, Yekaterina Y|Rychahou, Piotr G|Le, Anh-Thu|Scott, Timothy L|Flight, Robert M|Kim, Ji Tae|Harris, Jennifer|Liu, Jinpeng|Wang, Chi|Morris, Andrew J|Sivakumaran, Theru A|Fan, Teresa|Moseley, Hunter|Gao, Tianyan|Lee, Eun Y|Weiss, Heidi L|Heuer, Timo
PMID: 29872506
Journal: NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title: Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author: Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling
PMID: 29872721
Journal: Pathol Oncol Res. 2018 Jun 7. pii: 10.1007/s12253-018-0434-4.
Title: The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells.
Author: Sticz, Tamas|Molnar, Anna|Danko, Titanilla|Hujber, Zoltan|Petovari, Gabor|Nagy, Noemi|Vegso, Gyula|Kopper, Laszlo|Sebestyen, Anna
PMID: 29882195
Journal: Cell Cycle. 2018;17(10):1212-1219.
Title: IGF1/IGF1R and microRNA let-7e down-regulate each other and modulate proliferation and migration of colorectal cancer cells.
Author: Li, Zhenjun|Pan, Weihuo|Shen, Yi|Chen, Zhiliang|Zhang, Lihua|Zhang, Yuping|Luo, Quan|Ying, Xiaojiang
PMID: 29886785
Journal: Int J Mol Sci. 2018 Jun 14;19(6). pii: ijms19061763.
Title: Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin.
Author: Lin, Yueh-Ming|Chen, Chih-I|Hsiang, Yi-Ping|Hsu, Yung-Chia|Cheng, Kung-Chuan|Chien, Pei-Hsuan|Pan, Hsiao-Lin|Lu, Chien-Chang|Chen, Yun-Ju
PMID: 29899208
Journal: Oncotarget. 2018 May 29;9(41):26342-26352.
Title: PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2.
Author: Cheng, Ya-Min|Lin, Po-Lin|Wu, De-Wei|Wang, Lee|Huang, Chi-Chou|Lee, Huei
PMID: 29899863
Journal: Oncol Rep. 2018 Aug;40(2):1119-1128.
Title: uc.338 targets p21 and cyclin D1 via PI3K/AKT pathway activation to promote cell proliferation in colorectal cancer.
Author: Zhang, Yue|Wang, Shijia|Qian, Wenwei|Ji, Dongjian|Wang, Qingyuan|Zhang, Zhiyuan|Wang, Sen|Ji, Bing|Fu, Zan|Sun, Yueming
PMID: 29901203
Journal: Biomol Ther (Seoul). 2018 Jun 14. pii: biomolther.2018.054.
Title: Gomisin G Suppresses the Growth of Colon Cancer Cells by Attenuation of AKT Phosphorylation and Arrest of Cell Cycle Progression.
Author: Maharjan, Sony|Park, Byoung Kwon|Lee, Su In|Lim, Yoongho|Lee, Keunwook|Lee, Younghee|Kwon, Hyung-Joo
PMID: 29902863
Journal: Sci Rep. 2018 Jun 15;8(1):9204.
Title: Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Author: Fritsche-Guenther, Raphaela|Zasada, Christin|Mastrobuoni, Guido|Royla, Nadine|Rainer, Roman|Rossner, Florian|Pietzke, Matthias|Klipp, Edda|Sers, Christine|Kempa, Stefan
PMID: 29907857
Journal: Biochem Biophys Res Commun. 2018 Sep 5;503(2):843-848.
Title: Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and beta1 integrin/FAK-mediated signalling.
Author: Klobucar, Marko|Grbcic, Petra|Pavelic, Sandra Kraljevic|Jonjic, Nives|Visentin, Sarah|Sedic, Mirela
PMID: 29920241
Journal: J Transl Med. 2018 Jun 19;16(1):169.
Title: CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E-cadherin.
Author: Xu, Jingjing|Zhou, Jun|Dai, Hanjue|Liu, Fei|Li, Wenjing|Wang, Wenjuan|Guo, Feng
PMID: 29921293
Journal: Bioorg Med Chem. 2018 Aug 7;26(14):3899-3908.
Title: Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.
Author: He, Liu-Jun|Yang, Dong-Lin|Li, Shi-Qiang|Zhang, Ya-Jun|Tang, Yan|Lei, Jie|Frett, Brendan|Lin, Hui-Kuan|Li, Hong-Yu|Chen, Zhong-Zhu|Xu, Zhi-Gang
PMID: 29921474
Journal: Biol Chem. 2018 Jul 10.
Title: Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer.
Author: Zhang, Ling-Li|Zhang, Lian-Feng|Shi, Yun-Bo
PMID: 29924724
Journal: Oncol Lett. 2018 Jul;16(1):326-334.
Title: Cetuximab improves AZD6244 antitumor activity in colorectal cancer HT29 cells in vitro and in nude mice by attenuating HER3/Akt pathway activation.
Author: Zhang, Qin|Xiao, He|Jin, Feng|Li, Mengxia|Luo, Jia|Wang, Ge
PMID: 29928418
Journal: Bioinformatics. 2018 Jun 19. pii: 5040310.
Title: Modelling Signalling Networks from Perturbation Data.
Author: Dorel, Mathurin|Klinger, Bertram|Gross, Torsten|Sieber, Anja|Prahallad, Anirudh|Bosdriesz, Evert|Wessels, Lodewyk|Bluthgen, Nils
PMID: 29931053
Journal: Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(11):2358-2364.
Title: [Study of isobutyrylshikonin inhibiting proliferation of colon carcinoma cells through PI3K/Akt/m-TOR pathway].
Author: Zhong, Yu|Zheng, Xue-Bao|Cai, Kang-Rong|Huang, Qiong-Lin|Ye, Hua|Huang, Zhe|Wang, Yong-Cun|Zhu, Yu-Zhen
PMID: 29945391
Journal: Chin J Integr Med. 2018 Jun 8. pii: 10.1007/s11655-018-3002-6.
Title: Patrinia scabiosaefolia Inhibits Growth of 5-FU-Resistant Colorectal Carcinoma Cells via Induction of Apoptosis and Suppression of AKT Pathway.
Author: Huang, Si-Zhou|Liu, Wang-Yu|Huang, Yue|Shen, A-Ling|Liu, Li-Ya|Peng, Jun
PMID: 29948597
Journal: Int J Oncol. 2018 Sep;53(3):1313-1322.
Title: Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells in vitro.
Author: Yamaguchi, Masayoshi|Osuka, Satoru|Murata, Tomiyasu
PMID: 29956741
Journal: Biomed Pharmacother. 2018 Oct;106:109-116.
Title: Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling.
Author: Tian, Junhong|Yuan, Leilei
PMID: 29957460
Journal: Acta Biochim Biophys Sin (Shanghai). 2018 Aug 1;50(8):748-756.
Title: Cisplatin resistance in lung cancer is mediated by MACC1 expression through PI3K/AKT signaling pathway activation.
Author: Zhang, Qiang|Zhang, Bin|Sun, Leina|Yan, Qingna|Zhang, Yu|Zhang, Zhenfa|Su, Yanjun|Wang, Changli
PMID: 29961813
Journal: Biochem Biophys Res Commun. 2018 Sep 18;503(4):2333-2339.
Title: Knockdown of ADAM17 inhibits cell proliferation and increases oxaliplatin sensitivity in HCT-8 colorectal cancer through EGFR-PI3K-AKT activation.
Author: Zhang, Qi|Wang, Changyou|Han, Xuechao|Yang, Guanghua|Ge, Zhipeng|Zhang, Guozhi
PMID: 29964008
Journal: J Hematol Oncol. 2018 Jul 3;11(1):89.
Title: Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression.
Author: Li, Yang|Zeng, Changqian|Hu, Jialei|Pan, Yue|Shan, Yujia|Liu, Bing|Jia, Li
PMID: 29970122
Journal: J Cancer Res Ther. 2018 Jun;14(Supplement):S388-S393.
Title: Longan flower proanthocyanidins induce apoptosis in HT-29 colorectal carcinoma spheroids.
Author: Chung, Yuan-Chiang|Chiang, Hua-Che|Chang, Hsiang|Lin, Chih-Cheng|Lo, Li-Tsai|Wang, Ai-Yih|Chou, Kuo-Feng|Hsu, Chih-Ping
PMID: 29970694
Journal: Cell Death Dis. 2018 Jul 3;9(7):739.
Title: PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer.
Author: Wang, Qiang|Shi, Yan-Long|Zhou, Kai|Wang, Li-Li|Yan, Ze-Xuan|Liu, Yu-Lin|Xu, Li-Li|Zhao, Shi-Wei|Chu, Hui-Li|Shi, Ting-Ting|Ma, Qing-Hua|Bi, Jingwang
PMID: 29970892
Journal: Life Sci. 2018 Aug 15;207:532-549.
Title: Raddeanin A inhibits growth and induces apoptosis in human colorectal cancer through downregulating the Wnt/beta-catenin and NF-kappaB signaling pathway.
Author: Wang, Yu|Bao, Xiaowen|Zhao, Ang|Zhang, Jie|Zhang, Mingya|Zhang, Qi|Ma, Bo
PMID: 29972765
Journal: Oncogene. 2018 Jul 4. pii: 10.1038/s41388-018-0363-4.
Title: Alternative NF-kappaB signaling promotes colorectal tumorigenesis through transcriptionally upregulating Bcl-3.
Author: Tao, Yu|Liu, Zhanjie|Hou, Yingyong|Wang, Shouli|Liu, Sanhong|Jiang, Yuhang|Tan, Dan|Ge, Qiulin|Li, Cuifeng|Hu, Yiming|Liu, Zhi|Chen, Xi|Wang, Qi|Wang, Mingliang|Zhang, Xiaoren
PMID: 29973688
Journal: World J Surg Oncol. 2018 Jul 5;16(1):128.
Title: Differences in gene mutations according to gender among patients with colorectal cancer.
Author: Tsai, Yi-Jian|Huang, Sheng-Chieh|Lin, Hung-Hsin|Lin, Chun-Chi|Lan, Yuan-Tzu|Wang, Huann-Sheng|Yang, Shung-Haur|Jiang, Jeng-Kai|Chen, Wei-Shone|Lin, Tzu-Chen|Lin, Jen-Kou|Chang, Shih-Ching
PMID: 29976257
Journal: Int J Cancer. 2018 Jul 6.
Title: Activation of WNT/beta-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations.
Author: Park, Ye-Lim|Kim, Hwang-Phill|Cho, Young-Won|Min, Dong-Wook|Cheon, Seul-Ki|Lim, Yoo Joo|Song, Sang-Hyun|Jin Kim, Sung|Han, Sae-Won|Park, Kyu Joo|Kim, Tae-You
PMID: 29978469
Journal: J Physiol Pharmacol. 2018 Apr;69(2).
Title: Identification of potential small-molecule protein-protein inhibitors of cancer metastasis by 3D epitope-based computational screening.
Author: Raschka, S|More, S K|Devadoss, D|Zeng, B|Kuhn, L A|Basson, M D
PMID: 29980145
Journal: Cancer Res. 2018 Sep 1;78(17):4839-4852.
Title: Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.
Author: Stevens, Payton D|Wen, Yang-An|Xiong, Xiaopeng|Zaytseva, Yekaterina Y|Li, Austin T|Wang, Chi|Stevens, Ashley T|Farmer, Trevor N|Gan, Tong|Weiss, Heidi L|Inagaki, Masaki|Marchetto, Sylvie|Borg, Jean-Paul|Gao, Tianyan
PMID: 29980571
Journal: Cancer Lett. 2018 Oct 1;433:165-175.
Title: Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells.
Author: Liang, Kang-Hao|Tso, Hsien-Cheng|Hung, Shao-Hsi|Kuan, I-I|Lai, Jun-Kai|Ke, Feng-Yi|Chuang, Yi-Ting|Liu, I-Ju|Wang, Yi-Ping|Chen, Ruey-Hwa|Wu, Han-Chung
PMID: 29981429
Journal: Carcinogenesis. 2018 Jul 3;39(7):911-920.
Title: Nitric oxide-donating aspirin (NO-Aspirin) suppresses lung tumorigenesis in vitro and in vivo and these effects are associated with modulation of the EGFR signaling pathway.
Author: Song, Jung Min|Upadhyaya, Pramod|Kassie, Fekadu
PMID: 29982425
Journal: Int J Cancer. 2018 Jul 10.
Title: Clinical significance and biological function of WD repeat domain 54 as an oncogene in colorectal cancer.
Author: Yuan, Yuncang|Qi, Guoxiang|Shen, Hao|Guo, Aizhen|Cao, Fuao|Zhu, Yan|Xiao, Chunjie|Chang, Wenjun|Zheng, Shangyong
PMID: 29987896
Journal: Oncotarget. 2018 Jun 22;9(48):28951-28964.
Title: MicroRNA molecular profiling identifies potential signaling pathways conferring resistance to chemoradiation in locally-advanced rectal adenocarcinoma.
Author: Pettit, Cory|Webb, Amy|Walston, Steve|Chatterjee, Moumita|Chen, Wei|Frankel, Wendy|Croce, Carlo|Williams, Terence M
PMID: 29988972
Journal: Zhonghua Bing Li Xue Za Zhi. 2018 Jul 8;47(7):492-498.
Title: [Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations].
Author: Yu, L|Liu, Z Y|Jiao, J|Shi, X L|Cui, W L|Zhang, W|Li, Q X
PMID: 29996312
Journal: PLoS One. 2018 Jul 12;13(7):e0200163.
Title: Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth.
Author: Baumer, Nicole|Rehkamper, Jan|Appel, Neele|Terheyden, Lisa|Hartmann, Wolfgang|Wardelmann, Eva|Buchholz, Frank|Muller-Tidow, Carsten|Berdel, Wolfgang E|Baumer, Sebastian
PMID: 30001368
Journal: J BUON. 2018 May-Jun;23(3):574-578.
Title: Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway.
Author: Zhang, Yibing|Zhao, Yong|Guo, Jianyou|Cui, Haifeng|Liu, Sha
PMID: 30003721
Journal: J BUON. 2018 May-Jun;23(3):587-591.
Title: Antitumor effects of emodin in CACO-2 human colon carcinoma cells are mediated via apoptosis, cell cycle arrest and downregulation of PI3K/AKT signalling pathway.
Author: Ma, Qianzhang|Ding, Yuanquan|Wu, Zhenqi|Li, Yan
PMID: 30003723
Journal: Mol Cell Endocrinol. 2018 Jul 21. pii: S0303-7207(18)30221-1.
Title: Potential therapeutic targets for growth arrest of colorectal cancer cells exposed to PTHrP.
Author: Martin, Maria Julia|Gigola, Graciela|Zwenger, Ariel|Carriquiriborde, Martin|Gentil, Florencia|Gentili, Claudia
PMID: 30009852
Journal: Biochimie. 2018 Oct;153:171-180.
Title: 27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines.
Author: Warns, Jessica|Marwarha, Gurdeep|Freking, Natalie|Ghribi, Othman
PMID: 30009860
Journal: Oncol Lett. 2018 Aug;16(2):2638-2644.
Title: miRNA-29a inhibits colon cancer growth by regulation of the PTEN/Akt/GSK3beta and Wnt/beta-catenin signaling pathways.
Author: Han, Xiaofeng|Zheng, Jianwei|Wang, Yunlei|Gao, Zhigang
PMID: 30013659
Journal: Int J Oncol. 2018 Sep;53(3):1363-1373.
Title: Active fraction of clove induces apoptosis via PI3K/Akt/mTOR-mediated autophagy in human colorectal cancer HCT-116 cells.
Author: Liu, Minghua|Zhao, Ge|Zhang, Dan|An, Weixiao|Lai, Honglin|Li, Xiaofang|Cao, Shousong|Lin, Xiukun
PMID: 30015913
Journal: Biomed Pharmacother. 2018 Sep;105:1172-1182.
Title: Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway.
Author: Wang, Yan|Sun, Xiaohui|Ji, Kaihua|Du, Liqing|Xu, Chang|He, Ningning|Wang, Jinhan|Liu, Yang|Liu, Qiang
PMID: 30021354
Journal: Dev Reprod. 2018 Jun;22(2):133-142.
Title: Combination of BEZ235 and Metformin Has Synergistic Effect on Cell Viability in Colorectal Cancer Cells.
Author: Kim, Taewan|Kim, Taehyung|Choi, Soonyoung|Ko, Hyeran|Park, Deokbae|Lee, Youngki
PMID: 30023463
Journal: J Biomed Sci. 2018 Jul 19;25(1):57.
Title: Incomplete cellular reprogramming of colorectal cancer cells elicits an epithelial/mesenchymal hybrid phenotype.
Author: Hiew, Michele Sook Yuin|Cheng, Han Ping|Huang, Chiu-Jung|Chong, Kowit Yu|Cheong, Soon Keng|Choo, Kong Bung|Kamarul, Tunku
PMID: 30025541
Journal: Environ Toxicol Pharmacol. 2018 Sep;62:164-176.
Title: KT2 and RT2 modified antimicrobial peptides derived from Crocodylus siamensis Leucrocin I show activity against human colon cancer HCT-116 cells.
Author: Maijaroen, Surachai|Jangpromma, Nisachon|Daduang, Jureerut|Klaynongsruang, Sompong
PMID: 30031283
Journal: ACS Med Chem Lett. 2018 Jun 25;9(7):719-724.
Title: Discovery of an Orally Bioavailable Dual PI3K/mTOR Inhibitor Based on Sulfonyl-Substituted Morpholinopyrimidines.
Author: Shen, Sida|He, Xiangyu|Yang, Zheng|Zhang, Liang|Liu, Yingtao|Zhang, Zhiyuan|Wang, Weiwei|Liu, Wei|Li, Yufeng|Huang, Dong|Sun, Kai|Ni, Xiaojing|Yang, Xu|Chu, Xinxin|Cui, Yumin|Lv, Qiang|Lan, Jiong|Zhou, Fusheng
PMID: 30034607
Journal: Life Sci. 2018 Sep 1;208:167-174.
Title: Bisphenol A suppresses proliferation and induces apoptosis in colonic epithelial cells through mitochondrial and MAPK/AKT pathways.
Author: Qu, Wei|Zhao, Zhenguo|Chen, Sijin|Zhang, Lijin|Wu, Danlian|Chen, Zhigao
PMID: 30036487
Journal: Biochim Biophys Acta Gen Subj. 2018 Jul 20;1862(10):2281-2292.
Title: Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1alpha mediated signal pathway.
Author: Wang, Lin|Yu, Ziru|Ren, Shuyue|Song, Junke|Wang, Jinhua|Du, Guanhua
PMID: 30036603
Journal: Cell Death Dis. 2018 Jul 23;9(8):798.
Title: Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer.
Author: Pal, Deeksha|Tyagi, Ashish|Chandrasekaran, Balaji|Alattasi, Houda|Ankem, Murali K|Sharma, Arun K|Damodaran, Chendil
PMID: 30038258
Journal: Cell Physiol Biochem. 2018;48(3):1259-1273.
Title: Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation.
Author: Blanchard, Thomas G|Lapidus, Rena|Banerjee, Vivekjyoti|Bafford, Andrea C|Czinn, Steven J|Ahmed, Hafiz|Banerjee, Aditi
PMID: 30045022
Journal: Life Sci. 2018 Sep 15;209:43-51.
Title: Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation.
Author: Liang, Hung-Hua|Huang, Chien-Yu|Chou, Ching-Wen|Makondi, Precious Takondwa|Huang, Ming-Te|Wei, Po-Li|Chang, Yu-Jia
PMID: 30056019
Journal: Free Radic Biol Med. 2018 Oct;126:41-54.
Title: Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability.
Author: Afrin, Sadia|Giampieri, Francesca|Forbes-Hernandez, Tamara Y|Gasparrini, Massimiliano|Amici, Adolfo|Cianciosi, Danila|Quiles, Jose L|Battino, Maurizio
PMID: 30056083
Journal: J Dig Dis. 2018 Jul 29.
Title: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer.
Author: Tang, Chao-Tao|Gao, Yun-Jie|Ge, Zhi-Zheng
PMID: 30058122
Journal: Anticancer Res. 2018 Aug;38(8):4667-4676.
Title: Investigation into Enhancing Capecitabine Efficacy in Colorectal Cancer by Inhibiting Focal Adhesion Kinase Signaling.
Author: Sim, Jae Jun|Park, Min Hee|Baek, Jeong-Heum|Lee, Haejun|Jeong, Keun-Yeong|Kim, Hwan Mook
PMID: 30061234
Journal: Oncol Rep. 2018 Oct;40(4):1885-1896.
Title: GPR56 promotes proliferation of colorectal cancer cells and enhances metastasis via epithelialmesenchymal transition through PI3K/AKT signaling activation.
Author: Ji, Bing|Feng, Yifei|Sun, Ye|Ji, Dongjian|Qian, Wenwei|Zhang, Zhiyuan|Wang, Qingyuan|Zhang, Yue|Zhang, Chuan|Sun, Yueming
PMID: 30066935
Journal: Int J Biol Macromol. 2018 Nov;119:669-676.
Title: Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Author: Guo, Songjia|Liang, Xinxin|Guo, Min|Zhang, Xiaoli|Li, Zhuoyu
PMID: 30071226
Journal: Microrna. 2018 Aug 2. pii: MIRNA-EPUB-92141.
Title: Computational Analysis of miRNA and their Gene Targets Significantly Involved in Colorectal Cancer Progression.
Author: Kandhavelu, Jeyalakshmi|Subramanian, Kumar|Khan, Amber|Omar, Aadilah|Ruff, Paul|Penny, Clement
PMID: 30073936
Journal: J Cell Physiol. 2018 Aug 4.
Title: Restoration of miR-152 expression suppresses cell proliferation, survival, and migration through inhibition of AKT-ERK pathway in colorectal cancer.
Author: Ghazanchaei, Ardavan|Mansoori, Behzad|Mohammadi, Ali|Biglari, Alireza|Baradaran, Behzad
PMID: 30076720
Journal: Phytomedicine. 2018 Jul 15;46:131-141.
Title: Turmeric extract, with absorbable curcumin, has potent anti-metastatic effect in vitro and in vivo.
Author: Li, Mingyue|Yue, Grace Gar-Lee|Tsui, Stephen Kwok-Wing|Fung, Kwok-Pui|Lau, Clara Bik-San
PMID: 30097113
Journal: BMC Cancer. 2018 Aug 13;18(1):812.
Title: Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment.
Author: Tosi, Diego|Perez-Gracia, Esther|Atis, Salima|Vie, Nadia|Combes, Eve|Gabanou, Melissa|Larbouret, Christel|Jarlier, Marta|Mollevi, Caroline|Torro, Adeline|Del Rio, Maguy|Martineau, Pierre|Gongora, Celine
PMID: 30103709
Journal: BMC Cancer. 2018 Aug 15;18(1):822.
Title: Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes.
Author: Saber, Mona M|Al-Mahallawi, Abdulaziz M|Nassar, Noha N|Stork, Bjorn|Shouman, Samia A
PMID: 30111296
Journal: Cancer Lett. 2018 Nov 1;436:28-37.
Title: PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.
Author: Liu, Yifan|Yang, Eun Ju|Zhang, Baoyuan|Miao, Zhengqiang|Wu, Changjie|Lyu, Junfang|Tan, Kaeling|Poon, Terence Chuen Wai|Shim, Joong Sup
PMID: 30118842
Journal: Cancer Lett. 2018 Nov 1;436:119-128.
Title: Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway.
Author: Tan, Xiao|Zhang, Zhongqiang|Yao, Hongliang|Shen, Liangfang
PMID: 30118845
Journal: Biomed Pharmacother. 2018 Oct;106:1370-1377.
Title: MiR-92a promotes tumorigenesis of colorectal cancer, a transcriptomic and functional based study.
Author: Chen, Erfei|Li, Qiqi|Wang, Hua|Yang, Fangfang|Min, Lulu|Yang, Jin
PMID: 30119209
Journal: Sci Rep. 2018 Aug 20;8(1):12424.
Title: The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway.
Author: Ta, Ngoc Ly|Chakrabandhu, Krittalak|Huault, Sebastien|Hueber, Anne-Odile
PMID: 30127519
Journal: Mol Cancer Res. 2018 Aug 21. pii: 1541-7786.MCR-18-0341.
Title: Endothelial Cells Promote Colorectal Cancer Cell Survival by Activating the HER3-AKT Pathway in a Paracrine Fashion.
Author: Wang, Rui|Bhattacharya, Rajat|Ye, Xiangcang|Fan, Fan|Boulbes, Delphine R|Ellis, Lee M
PMID: 30131447
Journal: Biosci Rep. 2018 Sep 19;38(5). pii: BSR20180664.
Title: MiRNA-206 suppresses PGE2-induced colorectal cancer cell proliferation, migration, and invasion by targetting TM4SF1.
Author: Park, Young Ran|Seo, Seung Young|Kim, Se Lim|Zhu, Shi Mao|Chun, Sungkun|Oh, Jung-Mi|Lee, Min Ro|Kim, Seong Hun|Kim, In Hee|Lee, Seung Ok|Lee, Soo Teik|Kim, Sang Wook
PMID: 30135139
Journal: Biomed Pharmacother. 2018 Nov;107:860-866.
Title: Overexpression of hsa_circ_0007534 predicts unfavorable prognosis for osteosarcoma and regulates cell growth and apoptosis by affecting AKT/GSK-3beta signaling pathway.
Author: Li, Baoquan|Li, Xiaoguang
PMID: 30142548
Journal: Biochem Biophys Res Commun. 2018 Sep 18;503(4):3198-3204.
Title: The influence of aberrant expression of GLI1/p-S6K on colorectal cancer.
Author: Wang, Xuchao|Yao, Yizhou|Zhu, Xinguo
PMID: 30143258
Journal: Onco Targets Ther. 2018 Aug 14;11:4845-4855.
Title: Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics.
Author: Ge, Hua|Yan, Yan|Wu, Di|Huang, Yongsheng|Tian, Fei
PMID: 30147336
Journal: Acta Pharmacol Sin. 2018 Aug 31. pii: 10.1038/s41401-018-0157-9.
Title: Acetyl-11-keto-beta-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Author: Liu, Yong-Qing|Wang, Shi-Kang|Xu, Qing-Qing|Yuan, Hui-Qing|Guo, Yan-Xia|Wang, Qian|Kong, Feng|Lin, Zhao-Min|Sun, De-Qing|Wang, Rong-Mei|Lou, Hong-Xiang
PMID: 30171201
Journal: Cell Death Dis. 2018 Sep 5;9(9):911.
Title: Ipatasertib, a novel Akt inhibitor, induces transcription factor FoxO3a and NF-kappaB directly regulates PUMA-dependent apoptosis.
Author: Sun, Li|Huang, Yuan|Liu, Yeying|Zhao, Yujie|He, Xiaoxiao|Zhang, Lingling|Wang, Feng|Zhang, Yingjie
PMID: 30185800
Journal: Exp Ther Med. 2018 Sep;16(3):1758-1765.
Title: Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA-21-mediated activation of phosphatase and tensin homolog.
Author: Gao, Guangyi|Bian, Yinzhu|Qian, Hanqing|Yang, Mi|Hu, Jing|Li, Li|Yu, Lixia|Liu, Baorui|Qian, Xiaoping
PMID: 30186399
Journal: J Agric Food Chem. 2018 Sep 19;66(37):9635-9644.
Title: Cell Motility Facilitated by Mono(2-ethylhexyl) Phthalate via Activation of the AKT-beta-Catenin-IL-8 Axis in Colorectal Cancer.
Author: Luo, Chi-Wen|Hsiao, I-Ling|Wang, Jaw-Yuan|Wu, Chun-Chieh|Hung, Wen-Chun|Lin, Yu-Han|Chen, Tzu-Yi|Hsu, Yin-Chou|Cheng, Tian-Lu|Pan, Mei-Ren
PMID: 30188700
Journal: Phytomedicine. 2018 Sep 15;48:152-160.
Title: Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
Author: Han, Bing|Jiang, Pu|Li, Zhaoxing|Yu, Yang|Huang, Tao|Ye, Xiaoli|Li, Xuegang
PMID: 30195873
Journal: Biosci Biotechnol Biochem. 2018 Sep 10:1-10.
Title: Methyl-beta-cyclodextrin potentiates the BITC-induced anti-cancer effect through modulation of the Akt phosphorylation in human colorectal cancer cells.
Author: Yang, Qifu|Miyagawa, Miku|Liu, Xiaoyang|Zhu, Beiwei|Munemasa, Shintaro|Nakamura, Toshiyuki|Murata, Yoshiyuki|Nakamura, Yoshimasa
PMID: 30200817
Journal: Cancer Cell Int. 2018 Sep 6;18:131.
Title: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author: Fassan, Matteo|Vianello, Luca|Sacchi, Diana|Fanelli, Giuseppe N|Munari, Giada|Scarpa, Marco|Cappellesso, Rocco|Loupakis, Fotios|Lanza, Cristiano|Salmaso, Roberta|Mescoli, Claudia|Valeri, Nicola|Agostini, Marco|D'Angelo, Edoardo|Lonardi, Sara|Pucciarelli,
PMID: 30202242
Journal: J Cell Physiol. 2018 Sep 10.
Title: Neratinib augments the lethality of [regorafenib + sildenafil].
Author: Booth, Laurence|Roberts, Jane L|Rais, Rumeesa|Cutler, Richard E Jr|Diala, Irmina|Lalani, Alshad S|Hancock, John F|Poklepovic, Andrew|Dent, Paul
PMID: 30203445
Journal: J Cancer. 2018 Jul 30;9(17):3032-3037.
Title: NCOA4-RET fusion in colorectal cancer: Therapeutic challenge using patient-derived tumor cell lines.
Author: Kim, Sun Young|Oh, Seiyoon Oh|Kim, Kyung|Lee, Jeeyun|Kang, SoYoung|Kim, Kyoung-Mee|Lee, WooYong|Kim, Seung Tae|Nam, Dohyun Nam
PMID: 30210625
Journal: Transl Oncol. 2018 Dec;11(6):1379-1389.
Title: Sorcin a Potential Molecular Target for Cancer Therapy.
Author: Shabnam, Bano|Padmavathi, Ganesan|Banik, Kishore|Girisa, Sosmitha|Monisha, Javadi|Sethi, Gautam|Fan, Lu|Wang, Lingzhi|Mao, Xinliang|Kunnumakkara, Ajaikumar B
PMID: 30216763
Journal: Chem Biol Interact. 2018 Sep 12;296:26-33.
Title: 4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling.
Author: Sun, Dongdong|Zhang, Feng|Qian, Jie|Shen, Weixing|Fan, Huisen|Tan, Jiani|Li, Liu|Xu, Changliang|Yang, Ye|Cheng, Haibo
PMID: 30217479
Journal: J Cell Biochem. 2018 Sep 14.
Title: Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells.
Author: Tan, Fengbo|Huang, Yan|Pei, Qian|Liu, Heli|Pei, Haiping|Zhu, Hong
PMID: 30218452
Journal: Int J Mol Med. 2018 Nov;42(5):2503-2514.
Title: MicroRNA-7 inhibits colorectal cancer cell proliferation, migration and invasion via TYRO3 and phosphoinositide 3-kinase/protein B kinase/mammalian target of rapamycin pathway suppression.
Author: Qin, Ancheng|Qian, Weifeng
PMID: 30226533
Journal: Int J Oncol. 2018 Nov;53(5):1939-1952.
Title: KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer.
Author: Wang, Zao-Zao|Yang, Jie|Jiang, Bei-Hai|Di, Jia-Bo|Gao, Pin|Peng, Lin|Su, Xiang-Qian
PMID: 30226594
Journal: World J Gastroenterol. 2018 Sep 14;24(34):3884-3897.
Title: Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.
Author: Zeng, Yuan-Feng|Xiao, Yi-Sheng|Liu, Yong|Luo, Xiao-Jiang|Wen, Li-Dan|Liu, Qian|Chen, Min
PMID: 30228782
Journal: Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5499-5507.
Title: Down-regulation of miR-29a facilitates apoptosis of colorectal carcinoma cell SW480 and suppresses its Paclitaxel resistance.
Author: Yuan, L-L|Li, L|Liu, J-N|Mei, J|Lei, C-J
PMID: 30229821
Journal: J Exp Clin Cancer Res. 2018 Sep 19;37(1):231.
Title: HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways.
Author: Li, Qing|Wang, Cong|Wang, Yufeng|Sun, Liankang|Liu, Zhikui|Wang, Liang|Song, Tao|Yao, Yingmin|Liu, Qingguang|Tu, Kangsheng
PMID: 30231922
Journal: EBioMedicine. 2018 Sep 19. pii: S2352-3964(18)30379-7.
Title: Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data.
Author: Xiong, Yongfu|Deng, Ying|Wang, Kang|Zhou, He|Zheng, Xiangru|Si, Liangyi|Fu, Zhongxue
PMID: 30243491
Journal: Inflammopharmacology. 2018 Sep 22. pii: 10.1007/s10787-018-0534-5.
Title: Ponicidin inhibits pro-inflammatory cytokine TNF-alpha-induced epithelial-mesenchymal transition and metastasis of colorectal cancer cells via suppressing the AKT/GSK-3beta/Snail pathway.
Author: Zhang, Zhengguang|Xu, Jingjing|Liu, Bing|Chen, Feiyan|Li, Jiao|Liu, Yuchen|Zhu, Jiapeng|Shen, Cunsi
PMID: 30244296
Journal: Cell Death Dis. 2018 Sep 24;9(10):982.
Title: SP1-induced lncRNA-ZFAS1 contributes to colorectal cancer progression via the miR-150-5p/VEGFA axis.
Author: Chen, Xiaoxiang|Zeng, Kaixuan|Xu, Mu|Hu, Xiuxiu|Liu, Xiangxiang|Xu, Tao|He, Bangshun|Pan, Yuqin|Sun, Huiling|Wang, Shukui
PMID: 30250022
Journal: Cell Death Dis. 2018 Sep 24;9(10):998.
Title: Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer.
Author: Chen, Di|Xu, Li|Li, Xiaowei|Chu, Yi|Jiang, Mingzuo|Xu, Bing|Zhao, Min|Wang, Weijie|Wang, Hua|Kang, Huijie|Wang, Kai|Wu, Kaichun|Liang, Jie|Ren, Gui
PMID: 30250066
Journal: Oncol Lett. 2018 Oct;16(4):5131-5139.
Title: MiR-1260b inhibitor enhances the chemosensitivity of colorectal cancer cells to fluorouracil by targeting PDCD4/IGF1.
Author: Zhao, Jun|Cao, Jingjie|Zhou, Lurong|Du, Yunyi|Zhang, Xiaoling|Yang, Bo|Gao, Yangjun|Wang, Yu|Ma, Ning|Yang, Wei
PMID: 30250581
Journal: Oncotarget. 2018 Aug 31;9(68):32943-32957.
Title: Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells.
Author: Chung, Seyung S|Dutta, Pranabananda|Austin, David|Wang, Piwen|Awad, Adam|Vadgama, Jaydutt V
PMID: 30250641
Journal: J Cell Physiol. 2018 Sep 7.
Title: Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3beta/NFAT pathway.
Author: Tan, Zhen|Kang, Ting|Zhang, Xiuli|Tong, Yingying|Chen, Siyu
PMID: 30256405
Journal: Biomed Pharmacother. 2018 Nov;107:1712-1719.
Title: F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.
Author: Yao, Hui|Su, Song|Xia, Dong|Wang, Mingming|Li, Zonglin|Chen, Wangsheng|Ren, Lei|Xu, Liang
PMID: 30257389
Journal: Cancers (Basel). 2018 Sep 26;10(10). pii: cancers10100355.
Title: A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy.
Author: Gelfo, Valerio|Mazzeschi, Martina|Grilli, Giada|Lindzen, Moshit|Santi, Spartaco|D'Uva, Gabriele|Gyorffy, Balazs|Ardizzoni, Andrea|Yarden, Yosef|Lauriola, Mattia
PMID: 30261609
Journal: Cell Death Dis. 2018 Sep 27;9(10):1009.
Title: Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway.
Author: Li, Changcan|Liu, Xisheng|Liu, Yuan|Liu, Xueni|Wang, Rangrang|Liao, Jianhua|Wu, Shaohan|Fan, Junwei|Peng, Zhihai|Li, Bin|Wang, Zhaowen
PMID: 30262880
Journal: Oncol Rep. 2018 Sep 26.
Title: Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation.
Author: Chen, Yilin|Huang, Ying|Lu, Xingrong|Wang, Gaoxiong|Chi, Pan
PMID: 30272332
Journal: Cell Commun Signal. 2018 Oct 4;16(1):65.
Title: Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels.
Author: Zhang, Xin|Zhao, Yuechao|Wang, Changjun|Ju, Hongge|Liu, Wenjie|Zhang, Xiaohui|Miao, Shiying|Wang, Linfang|Sun, Qiang|Song, Wei
PMID: 30286765
Journal: Bull Cancer. 2018 Oct 8. pii: S0007-4551(18)30275-3.
Title: PTBP1 promotes tumorigenesis by regulating apoptosis and cell cycle in colon cancer.
Author: Li, Xiaona|Han, Fei|Liu, Wenbin|Shi, Xiaoyan
PMID: 30309622
Journal: Mol Ther Nucleic Acids. 2018 Sep 13;13:244-255.
Title: Antisense Oligonucleotides against miR-21 Inhibit the Growth and Metastasis of Colorectal Carcinoma via the DUSP8 Pathway.
Author: Ding, Tao|Cui, Panpan|Zhou, Ya|Chen, Chao|Zhao, Juanjuan|Wang, Hairong|Guo, Mengmeng|He, Zhixu|Xu, Lin
PMID: 30317164
Journal: Cancer Sci. 2018 Oct 15.
Title: NFIB Promotes Colorectal Cancer Cell Proliferation, EMT and 5-Fluorouracil Resistance.
Author: Liu, ZhengYi|Chen, JinHuang|Yuan, WenZheng|Ruan, HaiLong|Shu, Yan|Ji, JinTong|Wu, Liang|Tang, Qiang|Zhou, ZiLi|Zhang, XuDan|Cheng, YiFeng|He, ShuYa|Shu, XiaoGang
PMID: 30320939
Journal: J Cell Biochem. 2018 Oct 15.
Title: Silencing of FOXO6 inhibits the proliferation, invasion, and glycolysis in colorectal cancer cells.
Author: Li, Quanying|Tang, Hongna|Hu, Fangfang|Qin, Changjiang
PMID: 30321450
Journal: Int J Mol Sci. 2018 Oct 12;19(10). pii: ijms19103127.
Title: Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism.
Author: Kim, Young-Seon|Lee, Yoon-Mi|Oh, Taek-In|Shin, Dong Hoon|Kim, Geon-Hee|Kan, Sang-Yeon|Kang, Hyeji|Kim, Ji Hyung|Kim, Byeong Mo|Yim, Woo Jong|Lim, Ji-Hong
PMID: 30321984
Journal: Neoplasma. 2018 Sep 4. pii: 171225N841.
Title: Long non-coding RNA CRNDE may be associated with poor prognosis by promoting proliferation and inhibiting apoptosis of cervical cancer cells through targeting PI3K/AKT.
Author: Yang, H Y|Huang, C P|Cao, M M|Wang, Y F|Liu, Y
PMID: 30334449
Journal: Eur Rev Med Pharmacol Sci. 2018 Oct;22(19):6315-6323.
Title: LINC00657 promotes the development of colon cancer by activating PI3K/AKT pathway.
Author: Lei, Y|Wang, Y-H|Wang, X-F|Bai, J
PMID: 30338799
Journal: Cancer Biol Ther. 2018 Oct 25:1-9.
Title: RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-kappaB pathway.
Author: Lu, Peifen|Chen, Junjun|Yan, Lihong|Yang, Lijun|Zhang, Litao|Dai, Jie|Hao, Zixuan|Bai, Tao|Xi, Yanfeng|Li, Yahui|Kang, Zhiming|Xv, Jun|Sun, Gongqin|Yang, Tao
PMID: 30359168
Journal: J Cell Physiol. 2018 Oct 26.
Title: Knockdown of long noncoding RNA urothelial carcinoma associated 1 inhibits colorectal cancer cell proliferation and promotes apoptosis via modulating autophagy.
Author: Song, Fengling|Li, Lexing|Liang, Danyang|Zhuo, Yisha|Wang, Xueyi|Dai, Hanchuan
PMID: 30362538
Journal: World J Gastrointest Oncol. 2018 Oct 15;10(10):290-292.
Title: Inhibiting focal adhesion kinase: A potential target for enhancing therapeutic efficacy in colorectal cancer therapy.
Author: Jeong, Keun-Yeong
PMID: 30364839
Journal: Oncol Rep. 2018 Oct 18.
Title: MicroRNA-296 inhibits colorectal cancer cell growth and enhances apoptosis by targeting ARRB1-mediated AKT activation.
Author: Zhang, Zhe|Zhong, Xiaohua|Xiao, Yipin|Chen, Chao
PMID: 30365090
Journal: Int J Oncol. 2018 Oct 25.
Title: Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelialmesenchymal transition mediated by the FAK/AKT/MMPs axis.
Author: Liu, Shi-Quan|Xu, Chun-Yan|Wu, Wen-Hong|Fu, Zhen-Hua|He, Si-Wei|Qin, Meng-Bin|Huang, Jie-An
PMID: 30365116
Journal: BMC Cancer. 2018 Oct 26;18(1):1043.
Title: Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ beta -catenin signaling pathway.
Author: Razak, Suhail|Afsar, Tayyaba|Ullah, Asad|Almajwal, Ali|Alkholief, Musaed|Alshamsan, Aws|Jahan, Sarwat
PMID: 30367624
Journal: Biomed Pharmacother. 2018 Oct 1;108:1162-1169.
Title: Functions and mechanisms of microRNA-31 in human cancers.
Author: Yu, Tao|Ma, Pei|Wu, Deqin|Shu, Yongqian|Gao, Wen
PMID: 30372817
Journal: BMC Cancer. 2018 Nov 1;18(1):1056.
Title: The small organic molecule C19 binds and strengthens the KRAS4b-PDEdelta complex and inhibits growth of colorectal cancer cells in vitro and in vivo.
Author: Cruz-Nova, Pedro|Schnoor, Michael|Correa-Basurto, Jose|Bello, Martiniano|Briseno-Diaz, Paola|Rojo-Dominguez, Arturo|Ortiz-Mendoza, Carlos M|Guerrero-Aguirre, Jorge|Garcia-Vazquez, Francisco J|Hernandez-Rivas, Rosaura|Thompson-Bonilla, Maria Del Rocio|Varg
PMID: 30382908
Journal: Int J Mol Med. 2018 Nov 1.
Title: Resveratrol suppresses colon cancer growth by targeting the AKT/STAT3 signaling pathway.
Author: Li, Dan|Wang, Gangcheng|Jin, Guoguo|Yao, Ke|Zhao, Zhenjiang|Bie, Liangyu|Guo, Yongjun|Li, Ning|Deng, Wenying|Chen, Xiaobin|Chen, Beibei|Liu, Yuanyuan|Luo, Suxia|Guo, Zhiping
PMID: 30387805
Journal: Int Immunopharmacol. 2018 Oct 30;65:429-437.
Title: Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1alpha nuclear translocation.
Author: Zhang, Lin|Chen, Chang|Duanmu, Jiaxin|Wu, Yan|Tao, Jinhua|Yang, Aihua|Yin, Xiaoqin|Xiong, Biao|Gu, Jingya|Li, Chunling|Liu, Zhaoguo
PMID: 30388517