Primary Site >> Liver Cancer

Gene >> AKR1B10

Journal: Environ Health Perspect. 2001 Aug;109(8):833-7.
Title: Variability in aflatoxin-albumin adduct levels and effects of hepatitis B and C virus infection and glutathione S-transferase M1 and T1 genotype.
Author: Ahsan, H|Wang, L Y|Chen, C J|Tsai, W Y|Santella, R M
PMID: 11564620
Journal: Anticancer Drugs. 2001 Feb;12(2):129-32.
Title: Overexpression of aldose reductase in liver cancers may contribute to drug resistance.
Author: Lee, K W|Ko, B C|Jiang, Z|Cao, D|Chung, S S
PMID: 11261885
Journal: J Cancer Res Clin Oncol. 2003 Feb;129(2):100-6.
Title: The alteration of PTEN tumor suppressor expression and its association with the histopathological features of human primary hepatocellular carcinoma.
Author: Wan, X-W|Jiang, M|Cao, H-F|He, Y-Q|Liu, S-Q|Qiu, X-H|Wu, M-C|Wang, H-Y
PMID: 12669234
Journal: Biotechnol Appl Biochem. 2006 May;44(Pt 2):65-72.
Title: Characterization of a single-chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor.
Author: Cao, Limin|Shen, Guanxin|Zhu, Yinchang|Wang, Weiyu|Zhao, Xiaorong|Ye, Qing|Zhu, Huifen|Lu, Zhixian|Si, Jin
PMID: 16396634
Journal: Eur J Pharmacol. 2008 Apr 28;584(2-3):213-21.
Title: Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers.
Author: Verma, Malkhey|Martin, Hans-Joerg|Haq, Wahajul|O'Connor, Timothy R|Maser, Edmund|Balendiran, Ganesaratnam K
PMID: 18325492
Journal: Chem Biol Interact. 2009 Mar 16;178(1-3):134-7.
Title: Cancer biomarker AKR1B10 and carbonyl metabolism.
Author: Balendiran, Ganesaratnam K|Martin, Hans-Joerg|El-Hawari, Yasser|Maser, Edmund
PMID: 19028477
Journal: Gene. 2009 May 15;437(1-2):39-44.
Title: Structure and promoter characterization of aldo-keto reductase family 1 B10 gene.
Author: Liu, Ziwen|Zhong, Linlin|Krishack, Paulette A|Robbins, Sarah|Cao, Julia X|Zhao, Yupei|Chung, Stephen|Cao, Deliang
PMID: 19236911
Journal: J Hepatol. 2010 Feb;52(2):220-7.
Title: Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours.
Author: Heringlake, Stefan|Hofdmann, Michael|Fiebeler, Anette|Manns, Michael P|Schmiegel, Wolff|Tannapfel, Andrea
PMID: 20036025
Journal: Clin Cancer Res. 2010 May 1;16(9):2518-28.
Title: Combined functional genome survey of therapeutic targets for hepatocellular carcinoma.
Author: Satow, Reiko|Shitashige, Miki|Kanai, Yae|Takeshita, Fumitaka|Ojima, Hidenori|Jigami, Takafumi|Honda, Kazufumi|Kosuge, Tomoo|Ochiya, Takahiro|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20388846
Journal: Zhonghua Gan Zang Bing Za Zhi. 2010 Sep;18(9):666-71.
Title: [Effects of AKR1B10 gene silence on the growth and gene expression of HCC cell line MHCC97H].
Author: Wei, Wei|Liang, Hong-jie|Cui, Jie-feng|Guo, Kun|Kang, Xiao-nan|Cao, Ji|Su, Jian-jia|Li, Yuan|Liu, Yin-kun
PMID: 20943077
Journal: Liver Int. 2011 Jul;31(6):810-6.
Title: AKR1B10 expression is associated with less aggressive hepatocellular carcinoma: a clinicopathological study of 168 cases.
Author: Schmitz, Klaus J|Sotiropoulos, Georgios C|Baba, Hideo A|Schmid, Kurt W|Muller, Doris|Paul, Andreas|Auer, Thomas|Gamerith, Gabriele|Loeffler-Ragg, Judith
PMID: 21645211
Journal: Arch Toxicol. 2012 Mar;86(3):497-507.
Title: Mechanistic study on liver tumor promoting effects of flutamide in rats.
Author: Tawfeeq, Mohammad Monir|Hayashi, Hitomi|Shimamoto, Keisuke|Suzuki, Kazuhiko|Shibutani, Makoto|Inokuma, Hisashi|Mitsumori, Kunitoshi
PMID: 22076107
Journal: PLoS One. 2012;7(10):e46584.
Title: Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis.
Author: Starmann, Julia|Falth, Maria|Spindelbock, Walter|Lanz, Katja-Lauren|Lackner, Carolin|Zatloukal, Kurt|Trauner, Michael|Sultmann, Holger
PMID: 23071592
Journal: Liver Int. 2012 Oct;32(9):1382-90.
Title: Up-regulated aldo-keto reductase family 1 member B10 in chronic hepatitis C: association with serum alpha-fetoprotein and hepatocellular carcinoma.
Author: Sato, Shunsuke|Genda, Takuya|Hirano, Katsuharu|Tsuzura, Hironori|Narita, Yutaka|Kanemitsu, Yoshio|Kikuchi, Tetsu|Iijima, Katsuyori|Wada, Ryo|Ichida, Takafumi
PMID: 22681639
Journal: Sci Rep. 2012;2:280.
Title: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals.
Author: Moriguchi, Hisashi|Zhang, Yue|Mihara, Makoto|Sato, Chifumi
PMID: 22355790
Journal: Biochem J. 2012 Mar 1;442(2):273-82.
Title: Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells.
Author: Liu, Ziwen|Yan, Ruilan|Al-Salman, Ahmed|Shen, Yi|Bu, Yiwen|Ma, Jun|Luo, Di-Xian|Huang, Chenfei|Jiang, Yuyang|Wilber, Andrew|Mo, Yin-Yuan|Huang, Mei Chris|Zhao, Yupei|Cao, Deliang
PMID: 22329800
Journal: J Hepatol. 2013 Sep;59(3):510-7.
Title: SUOX is a promising diagnostic and prognostic biomarker for hepatocellular carcinoma.
Author: Jin, Guang-Zhi|Yu, Wen-Long|Dong, Hui|Zhou, Wei-Ping|Gu, Yi-Jin|Yu, Hao|Yu, Hua|Lu, Xin Yuan|Xian, Zhi-Hong|Liu, Yin-Kun|Cong, Wen-Ming|Wu, Meng-Chao
PMID: 23665285
Journal: PLoS One. 2013 Dec 31;8(12):e83465.
Title: Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China.
Author: Qi, Lu-Nan|Li, Le-Qun|Chen, Yuan-Yuan|Chen, Zhao-Hong|Bai, Tao|Xiang, Bang-De|Qin, Xiao|Xiao, Kai-Yin|Peng, Min-Hao|Liu, Zhi-Ming|Liu, Tang-Wei|Qin, Xue|Li, Shan|Han, Ze-Guang|Mo, Zeng-Nan|Santella, Regina M|Winkler, Cheryl A|O'Brien, Stephen J|Peng, Tao
PMID: 24391771
Journal: Toxicol Mech Methods. 2014 Dec;24(8):593-602.
Title: Molecular mechanisms of nano-selenium in mitigating hepatocellular carcinoma induced by N-nitrosodiethylamine (NDEA) in rats.
Author: Ahmed, Hanaa H|Khalil, Wagdy K B|Hamza, Amal H
PMID: 25156538
Journal: J Proteome Res. 2014 Aug 1;13(8):3645-54.
Title: Large-scale proteome quantification of hepatocellular carcinoma tissues by a three-dimensional liquid chromatography strategy integrated with sample preparation.
Author: Xu, Bo|Wang, Fangjun|Song, Chunxia|Sun, Zhen|Cheng, Kai|Tan, Yexiong|Wang, Hongyang|Zou, Hanfa
PMID: 24972180
Journal: Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):889-903.
Title: Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.
Author: Cousido-Siah, Alexandra|Ruiz, Francesc X|Mitschler, Andre|Porte, Sergio|de Lera, Angel R|Martin, Maria J|Manzanaro, Sonia|de la Fuente, Jesus A|Terwesten, Felix|Betz, Michael|Klebe, Gerhard|Farres, Jaume|Pares, Xavier|Podjarny, Alberto
PMID: 24598757
Journal: Int J Mol Sci. 2014 Apr 17;15(4):6556-68.
Title: Expression of aldo-keto reductase family 1 member b10 in the early stages of human hepatocarcinogenesis.
Author: Tsuzura, Hironori|Genda, Takuya|Sato, Shunsuke|Murata, Ayato|Kanemitsu, Yoshio|Narita, Yutaka|Ishikawa, Sachiko|Kikuchi, Tetsu|Mori, Masashi|Hirano, Katsuharu|Iijima, Katsuyori|Wada, Ryo|Ichida, Takafumi
PMID: 24747592
Journal: Chem Biol Interact. 2015 Jun 5;234:274-81.
Title: Down-regulation of aldo-keto reductase AKR1B10 gene expression by a phorbol ester via the ERK/c-Jun signaling pathway.
Author: Nishinaka, Toru|Miura, Takeshi|Sakou, Mihoko|Hidaka, Chiemi|Sasaoka, Chisato|Okamura, Asuka|Okamoto, Atsushi|Terada, Tomoyuki
PMID: 25463304
Journal: J Viral Hepat. 2015 Jul;22(7):617-24.
Title: Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection.
Author: Semmo, N|Weber, T|Idle, J R|Beyoglu, D
PMID: 25487531
Journal: PLoS One. 2015 Mar 4;10(3):e0119338.
Title: UNC50 prompts G1/S transition and proliferation in HCC by regulation of epidermal growth factor receptor trafficking.
Author: Fang, Zhou|Zhou, Linuo|Jiang, Songmin|Cao, Lihuan|Yu, Long
PMID: 25738771
Journal: Oncotarget. 2015 Nov 17;6(36):38967-82.
Title: Regulation of aldo-keto-reductase family 1 B10 by 14-3-3epsilon and their prognostic impact of hepatocellular carcinoma.
Author: Liu, Tzu-An|Jan, Yee-Jee|Ko, Bor-Sheng|Wu, Yi-Ju|Lu, Yi-Jhu|Liang, Shu-Man|Liu, Chia-Chia|Chen, Shyh-Chang|Wang, John|Shyue, Song-Kun|Liou, Jun-Yang
PMID: 26516929
Journal: J Gastroenterol Hepatol. 2016 Jul;31(7):1315-22.
Title: Impact of aldo-keto reductase family 1 member B10 on the risk of hepatitis C virus-related hepatocellular carcinoma.
Author: Sato, Shunsuke|Genda, Takuya|Ichida, Takafumi|Murata, Ayato|Tsuzura, Hironori|Narita, Yutaka|Kanemitsu, Yoshio|Ishikawa, Sachiko|Kikuchi, Tetsu|Mori, Masashi|Hirano, Katsuharu|Iijima, Katsuyori|Wada, Ryo|Nagahara, Akihito|Watanabe, Sumio
PMID: 26758591
Journal: Sci Rep. 2016 Mar 7;6:22746.
Title: Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate.
Author: Jin, Junfei|Liao, Weijia|Yao, Wenmin|Zhu, Rongping|Li, Yulan|He, Songqing
PMID: 26948042
Journal: World J Gastroenterol. 2016 Sep 7;22(33):7569-78.
Title: Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication.
Author: Murata, Ayato|Genda, Takuya|Ichida, Takafumi|Amano, Nozomi|Sato, Sho|Tsuzura, Hironori|Sato, Shunsuke|Narita, Yutaka|Kanemitsu, Yoshio|Shimada, Yuji|Hirano, Katsuharu|Iijima, Katsuyori|Wada, Ryo|Nagahara, Akihito|Watanabe, Sumio
PMID: 27672277
Journal: Oncol Lett. 2016 Dec;12(6):4821-4828.
Title: Prognostic significance of AKR1B10 gene expression in hepatocellular carcinoma and surrounding non-tumorous liver tissue.
Author: Sonohara, Fuminori|Inokawa, Yoshikuni|Hishida, Mitsuhiro|Kanda, Mitsuro|Nishikawa, Yoko|Yamada, Suguru|Fujii, Tsutomu|Sugimoto, Hiroyuki|Kodera, Yasuhiro|Nomoto, Shuji
PMID: 28105190
Journal: Hepatol Res. 2017 Mar;47(3):E85-E93.
Title: Aldo-keto reductase family 1 member B10 is associated with hepatitis B virus-related hepatocellular carcinoma risk.
Author: Mori, Masashi|Genda, Takuya|Ichida, Takafumi|Murata, Ayato|Kamei, Masato|Tsuzura, Hironori|Sato, Shunsuke|Narita, Yutaka|Kanemitsu, Yoshio|Ishikawa, Sachiko|Kikuchi, Tetsu|Shimada, Yuji|Hirano, Katsuharu|Iijima, Katsuyori|Sugimoto, Ken|Wada, Ryo|Nagahara,
PMID: 27084455
Journal: Nanoscale. 2017 Mar 30;9(13):4593-4600.
Title: Color resolution improvement of the dark-field microscopy imaging of single light scattering plasmonic nanoprobes for microRNA visual detection.
Author: Zhou, Jun|Gao, Peng Fei|Zhang, Hong Zhi|Lei, Gang|Zheng, Lin Ling|Liu, Hui|Huang, Cheng Zhi
PMID: 28322387
Journal: Sci Rep. 2017 Feb 9;7:42199.
Title: High expression of AKR1B10 predicts low risk of early tumor recurrence in patients with hepatitis B virus-related hepatocellular carcinoma.
Author: Wang, Yan-Yan|Qi, Lu-Nan|Zhong, Jian-Hong|Qin, Hong-Gui|Ye, Jia-Zhou|Lu, Shi-Dong|Ma, Liang|Xiang, Bang-De|Li, Le-Qun|You, Xue-Mei
PMID: 28181486
Journal: Breast. 2017 Feb;31:137-143.
Title: Overexpression and enhanced specific activity of aldoketo reductases (AKR1B1 & AKR1B10) in human breast cancers.
Author: Reddy, K Ashok|Kumar, P Uday|Srinivasulu, M|Triveni, B|Sharada, K|Ismail, Ayesha|Reddy, G Bhanuprakash
PMID: 27855345
Journal: Dig Dis Sci. 2018 Apr;63(4):934-944.
Title: Aldo-Keto Reductases as Early Biomarkers of Hepatocellular Carcinoma: A Comparison Between Animal Models and Human HCC.
Author: Torres-Mena, Julia Esperanza|Salazar-Villegas, Karla Noemi|Sanchez-Rodriguez, Ricardo|Lopez-Gabino, Belem|Del Pozo-Yauner, Luis|Arellanes-Robledo, Jaime|Villa-Trevino, Saul|Gutierrez-Nava, Maria Angelica|Perez-Carreon, Julio Isael
PMID: 29383608
Journal: Cancer Res. 2018 May 1;78(9):2332-2342.
Title: IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma.
Author: Cheng, Bowie Y|Lau, Eunice Y|Leung, Hoi-Wing|Leung, Carmen Oi-Ning|Ho, Nicole P|Gurung, Shilpa|Cheng, Lily K|Lin, Chi Ho|Lo, Regina Cheuk-Lam|Ma, Stephanie|Ng, Irene Oi-Lin|Lee, Terence K
PMID: 29483095
Journal: Sci Rep. 2018 Jul 23;8(1):11094.
Title: Biostatistics mining associated method identifies AKR1B10 enhancing hepatocellular carcinoma cell growth and degenerated by miR-383-5p.
Author: Wang, Junqing|Zhou, Yunyun|Fei, Xiaochun|Chen, Xuehua|Chen, Yongjun
PMID: 30038373
Journal: Aging (Albany NY). 2018 Aug 20;10(8):2079-2097.
Title: Integrated analysis of the impact of age on genetic and clinical aspects of hepatocellular carcinoma.
Author: Atyah, Manar|Yin, Yi-Rui|Zhou, Chen-Hao|Zhou, Qiang|Chen, Wan-Yong|Dong, Qiong-Zhu|Ren, Ning
PMID: 30125264
Journal: Med Sci Monit. 2018 Oct 17;24:7414-7423.
Title: Immunohistochemistry Detects Increased Expression of Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) in Early-Stage Hepatocellular Carcinoma.
Author: Han, Chao|Gao, Lanzhu|Zhao, Lianrong|Sheng, Qiuju|Zhang, Chong|An, Ziying|Xia, Tingting|Ding, Yang|Wang, Jingyan|Bai, Han|Dou, Xiaoguang
PMID: 30328412
Journal: PLoS One. 2018 Oct 31;13(10):e0205747.
Title: Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease.
Author: Pettinelli, Paulina|Arendt, Bianca M|Teterina, Anastasia|McGilvray, Ian|Comelli, Elena M|Fung, Scott K|Fischer, Sandra E|Allard, Johane P
PMID: 30379862