Primary Site >> Liver Cancer
Gene >> AKR1B10
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Ref: Overexpression of aldose reductase in liver cancers may contribute to drug resistance. PMID: 11261885 Ref: Variability in aflatoxin-albumin adduct levels and effects of hepatitis B and C virus infection and glutathione S-transferase M1 and T1 genotype. PMID: 11564620 |
Ref: The alteration of PTEN tumor suppressor expression and its association with the histopathological features of human primary hepatocellular carcinoma. PMID: 12669234 |
Ref: Characterization of a single-chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor. PMID: 16396634 |
Ref: Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. PMID: 18325492 |
Ref: Cancer biomarker AKR1B10 and carbonyl metabolism. PMID: 19028477 Ref: Structure and promoter characterization of aldo-keto reductase family 1 B10 gene. PMID: 19236911 |
Ref: Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours. PMID: 20036025 Ref: Combined functional genome survey of therapeutic targets for hepatocellular carcinoma. PMID: 20388846 Ref: [Effects of AKR1B10 gene silence on the growth and gene expression of HCC cell line MHCC97H]. PMID: 20943077 |
Ref: AKR1B10 expression is associated with less aggressive hepatocellular carcinoma: a clinicopathological study of 168 cases. PMID: 21645211 |
Ref: Mechanistic study on liver tumor promoting effects of flutamide in rats. PMID: 22076107 Ref: Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells. PMID: 22329800 Ref: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. PMID: 22355790 Ref: Up-regulated aldo-keto reductase family 1 member B10 in chronic hepatitis C: association with serum alpha-fetoprotein and hepatocellular carcinoma. PMID: 22681639 Ref: Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis. PMID: 23071592 |
Ref: SUOX is a promising diagnostic and prognostic biomarker for hepatocellular carcinoma. PMID: 23665285 Ref: Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China. PMID: 24391771 |
Ref: Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design. PMID: 24598757 Ref: Expression of aldo-keto reductase family 1 member b10 in the early stages of human hepatocarcinogenesis. PMID: 24747592 Ref: Large-scale proteome quantification of hepatocellular carcinoma tissues by a three-dimensional liquid chromatography strategy integrated with sample preparation. PMID: 24972180 Ref: Molecular mechanisms of nano-selenium in mitigating hepatocellular carcinoma induced by N-nitrosodiethylamine (NDEA) in rats. PMID: 25156538 |
Ref: Down-regulation of aldo-keto reductase AKR1B10 gene expression by a phorbol ester via the ERK/c-Jun signaling pathway. PMID: 25463304 Ref: Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection. PMID: 25487531 Ref: UNC50 prompts G1/S transition and proliferation in HCC by regulation of epidermal growth factor receptor trafficking. PMID: 25738771 Ref: Regulation of aldo-keto-reductase family 1 B10 by 14-3-3epsilon and their prognostic impact of hepatocellular carcinoma. PMID: 26516929 |
Ref: Impact of aldo-keto reductase family 1 member B10 on the risk of hepatitis C virus-related hepatocellular carcinoma. PMID: 26758591 Ref: Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate. PMID: 26948042 Ref: Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication. PMID: 27672277 Ref: Prognostic significance of AKR1B10 gene expression in hepatocellular carcinoma and surrounding non-tumorous liver tissue. PMID: 28105190 |
Ref: Aldo-keto reductase family 1 member B10 is associated with hepatitis B virus-related hepatocellular carcinoma risk. PMID: 27084455 Ref: Overexpression and enhanced specific activity of aldoketo reductases (AKR1B1 & AKR1B10) in human breast cancers. PMID: 27855345 Ref: High expression of AKR1B10 predicts low risk of early tumor recurrence in patients with hepatitis B virus-related hepatocellular carcinoma. PMID: 28181486 Ref: Color resolution improvement of the dark-field microscopy imaging of single light scattering plasmonic nanoprobes for microRNA visual detection. PMID: 28322387 |
Ref: Aldo-Keto Reductases as Early Biomarkers of Hepatocellular Carcinoma: A Comparison Between Animal Models and Human HCC. PMID: 29383608 Ref: IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma. PMID: 29483095 Ref: Biostatistics mining associated method identifies AKR1B10 enhancing hepatocellular carcinoma cell growth and degenerated by miR-383-5p. PMID: 30038373 Ref: Integrated analysis of the impact of age on genetic and clinical aspects of hepatocellular carcinoma. PMID: 30125264 Ref: Immunohistochemistry Detects Increased Expression of Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) in Early-Stage Hepatocellular Carcinoma. PMID: 30328412 Ref: Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease. PMID: 30379862 |