Primary Site >> Colorectal Cancer

Gene >> AIM2

Journal: Genes Chromosomes Cancer. 2007 Dec;46(12):1080-9.
Title: The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
Author: Woerner, Stefan M|Kloor, Matthias|Schwitalle, Yvette|Youmans, Hanni|Doeberitz, Magnus von Knebel|Gebert, Johannes|Dihlmann, Susanne
PMID: 17726700
Journal: Glycobiology. 2009 Jul;19(7):726-34.
Title: Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.
Author: Patsos, Georgios|Andre, Sabine|Roeckel, Nina|Gromes, Roland|Gebert, Johannes|Kopitz, Jurgen|Gabius, Hans-Joachim
PMID: 19293232
Journal: Int J Cancer. 2010 Apr 15;126(8):1838-49.
Title: Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells.
Author: Patsos, Georgios|Germann, Anja|Gebert, Johannes|Dihlmann, Susanne
PMID: 19795419
Journal: Mol Carcinog. 2010 Feb;49(2):175-82.
Title: Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation.
Author: Michel, Sara|Kloor, Matthias|Singh, Sandhya|Gdynia, Georg|Roth, Wilfried|von Knebel Doeberitz, Magnus|Schirmacher, Peter|Blaker, Hendrik
PMID: 19852062
Journal: Fam Cancer. 2010 Jun;9(2):173-9.
Title: Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome.
Author: Reuschenbach, Miriam|Kloor, Matthias|Morak, Monika|Wentzensen, Nicolas|Germann, Anja|Garbe, Yvette|Tariverdian, Mirjam|Findeisen, Peter|Neumaier, Michael|Holinski-Feder, Elke|von Knebel Doeberitz, Magnus
PMID: 19957108
Journal: Oncogene. 2012 Mar 8;31(10):1242-53.
Title: Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers.
Author: Lee, J|Li, L|Gretz, N|Gebert, J|Dihlmann, S
PMID: 21804607
Journal: Int J Cancer. 2014 Nov 15;135(10):2387-96.
Title: Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients.
Author: Dihlmann, Susanne|Tao, Sha|Echterdiek, Fabian|Herpel, Esther|Jansen, Lina|Chang-Claude, Jenny|Brenner, Hermann|Hoffmeister, Michael|Kloor, Matthias
PMID: 24729378
Journal: Cell. 2015 Jul 2;162(1):18-20.
Title: AIMing 2 Curtail Cancer.
Author: Rommereim, Leah M|Subramanian, Naeha
PMID: 26140588
Journal: Oncotarget. 2015 Oct 20;6(32):33456-69.
Title: Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components.
Author: Liu, Rongrong|Truax, Agnieszka D|Chen, Liang|Hu, Peizhen|Li, Zengshan|Chen, Jun|Song, Chaojun|Chen, Lihua|Ting, Jenny Pan-Yun
PMID: 26378020
Journal: Cancer Discov. 2015 Sep;5(9):899-900.
Title: AIM2 Blocks Colon Cancer in Three Ways.
Author:
PMID: 26198813
Journal: Nat Med. 2015 Aug;21(8):906-13.
Title: Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Author: Wilson, Justin E|Petrucelli, Alex S|Chen, Liang|Koblansky, A Alicia|Truax, Agnieszka D|Oyama, Yoshitaka|Rogers, Arlin B|Brickey, W June|Wang, Yuli|Schneider, Monika|Muhlbauer, Marcus|Chou, Wei-Chun|Barker, Brianne R|Jobin, Christian|Allbritton, Nancy L|Ra
PMID: 26107252
Journal: Cell. 2015 Jul 2;162(1):45-58.
Title: Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Author: Man, Si Ming|Zhu, Qifan|Zhu, Liqin|Liu, Zhiping|Karki, Rajendra|Malik, Ankit|Sharma, Deepika|Li, Liyuan|Malireddi, R K Subbarao|Gurung, Prajwal|Neale, Geoffrey|Olsen, Scott R|Carter, Robert A|McGoldrick, Daniel J|Wu, Gang|Finkelstein, David|Vogel, Peter|G
PMID: 26095253
Journal: PLoS One. 2015 Mar 27;10(3):e0121980.
Title: Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.
Author: Staffa, Laura|Echterdiek, Fabian|Nelius, Nina|Benner, Axel|Werft, Wiebke|Lahrmann, Bernd|Grabe, Niels|Schneider, Martin|Tariverdian, Mirjam|von Knebel Doeberitz, Magnus|Blaker, Hendrik|Kloor, Matthias
PMID: 25816162
Journal: Eur J Immunol. 2016 Feb;46(2):269-80.
Title: AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity.
Author: Man, Si Ming|Karki, Rajendra|Kanneganti, Thirumala-Devi
PMID: 26626159
Journal: Cell Mol Life Sci. 2016 Dec;73(23):4383-4395.
Title: Absent in melanoma 2 proteins in the development of cancer.
Author: Choubey, Divaker
PMID: 27328971
Journal: Cell Mol Immunol. 2017 Jan;14(1):127-142.
Title: The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway.
Author: Ratsimandresy, Rojo A|Indramohan, Mohanalaxmi|Dorfleutner, Andrea|Stehlik, Christian
PMID: 27524110
Journal: Cancer Immunol Res. 2017 Feb;5(2):94-99.
Title: Inflammasomes and Cancer.
Author: Karki, Rajendra|Man, Si Ming|Kanneganti, Thirumala-Devi
PMID: 28093447
Journal: Cell Mol Life Sci. 2017 Jul;74(13):2395-2411.
Title: Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.
Author: He, Liangmei|Chen, Yayun|Wu, Yuanbing|Xu, Ying|Zhang, Zixiang|Liu, Zhiping
PMID: 28224203
Journal: Onco Targets Ther. 2017 Feb 13;10:811-817.
Title: AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway.
Author: Chen, Jianjun|Wang, Zhenjun|Yu, Sanshui
PMID: 28243117
Journal: Cell Res. 2017 Jun;27(6):722-723.
Title: An evolving function of DNA-containing exosomes in chemotherapy-induced immune response.
Author: Kurywchak, Paul|Kalluri, Raghu
PMID: 28524163