Literatures

Primary Site >> Colorectal Cancer

Gene >> AIFM1

1.
Journal:	Br J Pharmacol. 2002 Nov;137(5):608-20.
Title:	Molecular mechanisms of sulfasalazine-induced T-cell apoptosis.
Author:	Liptay, Susanne\|Fulda, Simone\|Schanbacher, Marta\|Bourteele, Soizic\|Ferri, Karine F\|Kroemer, Guido\|Adler, Guido\|Debatin, Klaus M\|Schmid, Roland M
PMID:	12381674

2.
Journal:	FEBS Lett. 2002 Jul 31;524(1-3):163-71.
Title:	A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF).
Author:	Ohiro, Yoichi\|Garkavtsev, Igor\|Kobayashi, Shinichiro\|Sreekumar, Kodangattil R\|Nantz, Regan\|Higashikubo, Bryan T\|Duffy, Shannon L\|Higashikubo, Ryuji\|Usheva, Anny\|Gius, David\|Kley, Nikolai\|Horikoshi, Nobuo
PMID:	12135761

3.
Journal:	Cancer Res. 2003 Aug 15;63(16):5118-25.
Title:	Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
Author:	Tillman, David M\|Izeradjene, Kamel\|Szucs, Kinga Szekely\|Douglas, Leslie\|Houghton, Janet A
PMID:	12941843

4.
Journal:	Carcinogenesis. 2004 Feb;25(2):179-87.
Title:	Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	14604899

5.
Journal:	Carcinogenesis. 2004 Oct;25(10):1867-77. Epub 2004 Jun 17.
Title:	Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	15205359

6.
Journal:	EMBO J. 2005 Aug 3;24(15):2815-26. Epub 2005 Jul 7.
Title:	AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells.
Author:	Urbano, Alexander\|Lakshmanan, Umayal\|Choo, Poh Heok\|Kwan, Jair Chau\|Ng, Poh Yong\|Guo, Ke\|Dhakshinamoorthy, Saravanakumar\|Porter, Alan
PMID:	16001080

7.
Journal:	Apoptosis. 2005 Oct;10(5):1175-86.
Title:	Irreversible pan-ErbB tyrosine kinase inhibitor CI-1033 induces caspase-independent apoptosis in colorectal cancer DiFi cell line.
Author:	Skvortsov, S\|Skvortsova, I\|Sarg, B\|Loeffler-Ragg, J\|Lindner, H\|Lukas, P\|Tabernero, J\|Zwierzina, H
PMID:	16151650

8.
Journal:	Life Sci. 2005 Sep 2;77(16):2059-70.
Title:	Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.
Author:	Park, Young Chul\|Jeong, Jin Hee\|Park, Ki Jae\|Choi, Hong Jo\|Park, Yeong Min\|Jeong, Byung Kap\|Higuchi, Yoshihiro\|Yoo, Young Hyun
PMID:	15946692

9.
Journal:	Food Chem Toxicol. 2005 Oct;43(10):1483-95.
Title:	Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
Author:	Ho, Yuan-Soon\|Wu, Chih-Hsiung\|Chou, Hsiao-Min\|Wang, Ying-Jan\|Tseng, How\|Chen, Chien-Ho\|Chen, Li-Ching\|Lee, Chia-Hwa\|Lin, Shyr-Yi
PMID:	15919146

10.
Journal:	World J Gastroenterol. 2005 May 28;11(20):3040-5.
Title:	Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells.
Author:	Yang, Kuo-Ching\|Uen, Yih-Huei\|Suk, Fat-Moon\|Liang, Yu-Chih\|Wang, Ying-Jan\|Ho, Yuan-Soon\|Li, I-Hsuan\|Lin, Shyr-Yi
PMID:	15918186

11.
Journal:	J Histochem Cytochem. 2005 Feb;53(2):229-35.
Title:	Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa.
Author:	Holubec, Hana\|Payne, Claire M\|Bernstein, Harris\|Dvorakova, Katerina\|Bernstein, Carol\|Waltmire, Caroline N\|Warneke, James A\|Garewal, Harinder
PMID:	15684335

12.
Journal:	Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20.
Title:	Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	15661804

13.
Journal:	Cancer Res. 2006 Apr 15;66(8):4191-7.
Title:	Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Author:	Schmitt, Elise\|Maingret, Loic\|Puig, Pierre-Emmanuel\|Rerole, Anne-Laure\|Ghiringhelli, Francois\|Hammann, Arlette\|Solary, Eric\|Kroemer, Guido\|Garrido, Carmen
PMID:	16618741

14.
Journal:	Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title:	Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author:	Nagy, Katalin\|Szekely-Szuts, Kinga\|Izeradjene, Kamel\|Douglas, Leslie\|Tillman, Mike\|Barti-Juhasz, Helga\|Dominici, Massimo\|Spano, Carlotta\|Luca Cervo, Gian\|Conte, Pierfranco\|Houghton, Janet A\|Mihalik, Rudolf\|Kopper, Laszlo\|Petak, Istvan
PMID:	16998592

15.
Journal:	Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):223-33.
Title:	Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
Author:	Lu, Pin-Hsuan\|Kung, Fan-Lu\|Kuo, Sheng-Chu\|Chueh, Shih-Chieh\|Guh, Jih-Hwa
PMID:	17102938

16.
Journal:	APMIS. 2006 Dec;114(12):867-73.
Title:	Immunohistochemical and mutational analysis of apoptosis-inducing factor (AIF) in colorectal carcinomas.
Author:	Jeong, Eun Goo\|Lee, Jong Woo\|Soung, Young Hwa\|Nam, Suk Woo\|Kim, Sang Ho\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	17207087

17.
Journal:	Food Chem Toxicol. 2007 Jun;45(6):935-44.
Title:	Induction of apoptosis and cell-cycle arrest in human colon cancer cells by meclizine.
Author:	Lin, Jiunn-Chang\|Ho, Yuan-Soon\|Lee, Jie-Jen\|Liu, Chien-Liang\|Yang, Tsen-Long\|Wu, Chih-Hsiung
PMID:	17222494

18.
Journal:	J Biol Chem. 2007 Oct 12;282(41):30331-40.
Title:	DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis.
Author:	Gong, Min\|Hay, Sam\|Marshall, Ker R\|Munro, Andrew W\|Scrutton, Nigel S
PMID:	17711848

19.
Journal:	J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title:	Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author:	Huerta, Sergio\|Heinzerling, John H\|Anguiano-Hernandez, Yu-Mei\|Huerta-Yepez, Sara\|Lin, Jeffrey\|Chen, David\|Bonavida, Benjamin\|Livingston, Edward H
PMID:	17603079

20.
Journal:	Int J Cancer. 2007 Oct 15;121(8):1670-9.
Title:	Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells.
Author:	Ko, Ching-Huai\|Shen, Shing-Chuan\|Yang, Liang-Yo\|Lin, Cheng-Wei\|Chen, Yen-Chou
PMID:	17597109

21.
Journal:	Mol Cell Biochem. 2007 Jun;300(1-2):227-37.
Title:	A highly polar xanthophyll of 9'-cis-neoxanthin induces apoptosis in HCT116 human colon cancer cells through mitochondrial dysfunction.
Author:	Terasaki, Masaru\|Asai, Akira\|Zhang, Hong\|Nagao, Akihiko
PMID:	17186379

22.
Journal:	Apoptosis. 2008 Jun;13(6):782-9.
Title:	The bisphosphonate zoledronic acid inhibits the growth of HCT-116 colon carcinoma cells and induces tumor cell apoptosis.
Author:	Sewing, Lilian\|Steinberg, Florian\|Schmidt, Harald\|Goke, Rudiger
PMID:	18437576

23.
Journal:	J Cell Mol Med. 2008 Jun;12(3):1005-22.
Title:	Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway.
Author:	Ghavami, Saeid\|Asoodeh, Ahmad\|Klonisch, Thomas\|Halayko, Andrew J\|Kadkhoda, Kamran\|Kroczak, Tadeusz J\|Gibson, Spencer B\|Booy, Evan P\|Naderi-Manesh, Hossein\|Los, Marek
PMID:	18494941

24.
Journal:	Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov;378(5):447-57.
Title:	Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells.
Author:	Chen, Tzu-Hsuan\|Pan, Shiow-Lin\|Guh, Jih-Hwa\|Chen, Chien-Chih\|Huang, Yao-Ting\|Pai, Hui-Chen\|Teng, Che-Ming
PMID:	18607570

25.
Journal:	Food Chem Toxicol. 2008 Dec;46(12):3753-8.
Title:	Induction of apoptosis in HT-29 colon cancer cells by crude saponin from Platycodi Radix.
Author:	Kim, Jae-Yong\|Park, Kyoung-Wuk\|Moon, Kwang-Deog\|Lee, Mi-Kyung\|Choi, Jina\|Yee, Sung-Tae\|Shim, Ki-Hwan\|Seo, Kwon-Il
PMID:	18955103

26.
Journal:	J Surg Res. 2009 Jan;151(1):163-70. Epub 2007 Dec 3.
Title:	Apoptosis-inducing factor and colon cancer.
Author:	Millan, Alejandro\|Huerta, Sergio
PMID:	18061616

27.
Journal:	Nitric Oxide. 2009 May;20(3):182-94.
Title:	In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF.
Author:	Huerta, Sergio\|Baay-Guzman, Guillermina\|Gonzalez-Bonilla, Cesar R\|Livingston, Edward H\|Huerta-Yepez, Sara\|Bonavida, Benjamin
PMID:	19105980

28.
Journal:	Toxicol Lett. 2009 Jul 24;188(2):142-7.
Title:	Mechanisms of thiosulfinates from Allium tuberosum L.-induced apoptosis in HT-29 human colon cancer cells.
Author:	Lee, Ju-Hye\|Yang, Hee-Sun\|Park, Kyoung-Wuk\|Kim, Jae-Yong\|Lee, Mi-Kyung\|Jeong, Il-Yun\|Shim, Ki-Hwan\|Kim, Young-Sook\|Yamada, Koji\|Seo, Kwon-Il
PMID:	19446247

29.
Journal:	Food Chem Toxicol. 2009 Sep;47(9):2157-62.
Title:	Anti-proliferative effects of Lethariella zahlbruckneri extracts in human HT-29 human colon cancer cells.
Author:	Ren, Mei Rong\|Hur, Jae-Seoun\|Kim, Jae Yong\|Park, Kyoung-Wuk\|Park, Seong-Chan\|Seong, Chi-Nam\|Jeong, Il-Yun\|Byun, Myung-Woo\|Lee, Mi-Kyung\|Seo, Kwon-Il
PMID:	19501127

30.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Jul;12(4):391-4.
Title:	[Expression of AIF and caspase-3 in colorectal carcinoma, adenoma, and normal mucosa and its correlation].
Author:	Guan, Jian-ting\|Wang, Ling\|Wang, Yong\|Li, Yuan\|Wang, Rong\|Zhang, Wen-yan\|Zhan, Lan\|Zhou, Zong-guang
PMID:	19598027

31.
Journal:	Cancer Lett. 2010 Jul 1;293(1):23-30.
Title:	Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
Author:	Choi, Sujin\|Choi, Yunjin\|Dat, Nguyen Tien\|Hwangbo, Cheol\|Lee, Jung Joon\|Lee, Jeong-Hyung
PMID:	20056314

32.
Journal:	Oncol Rep. 2010 Aug;24(2):449-55.
Title:	Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway.
Author:	Chen, Nian-Gu\|Chen, Kuan-Tin\|Lu, Chi-Cheng\|Lan, Yu-Hsuan\|Lai, Cheng-Hung\|Chung, Yang-Tsung\|Yang, Jai-Sing\|Lin, Yung-Chang
PMID:	20596632

33.
Journal:	Oncol Rep. 2011 Nov;26(5):1091-7.
Title:	Expression of p53 and DR5 in normal and malignant tissues of colorectal cancer: correlation with advanced stages.
Author:	Perraud, Aurelie\|Akil, Hussein\|Nouaille, Michelle\|Petit, Daniel\|Labrousse, Francois\|Jauberteau, Marie-Odile\|Mathonnet, Muriel
PMID:	21805040

34.
Journal:	Biosci Biotechnol Biochem. 2011;75(7):1306-11.
Title:	Isoegomaketone induces apoptosis through caspase-dependent and caspase-independent pathways in human DLD1 cells.
Author:	Cho, Byoung Ok\|Jin, Chang Hyun\|Park, Yong Dae\|Ryu, Hyung Won\|Byun, Myung Woo\|Seo, Kwon Il\|Jeong, Il Yun
PMID:	21737934

35.
Journal:	Oncol Rep. 2012 Jun;27(6):1787-93.
Title:	Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age.
Author:	Perraud, Aurelie\|Akil, Hussein\|Nouaille, Michelle\|Petit, Daniel\|Labrousse, Francois\|Jauberteau, Marie-Odile\|Mathonnet, Muriel
PMID:	22447208

36.
Journal:	PLoS One. 2012;7(5):e36418.
Title:	Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor.
Author:	Wang, Lihong\|Liu, Liping\|Shi, Yan\|Cao, Hanwei\|Chaturvedi, Rupesh\|Calcutt, M Wade\|Hu, Tianhui\|Ren, Xiubao\|Wilson, Keith T\|Polk, D Brent\|Yan, Fang
PMID:	22574158

37.
Journal:	Free Radic Biol Med. 2012 Aug 1;53(3):488-97.
Title:	Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells.
Author:	Cole-Ezea, Patience\|Swan, Dan\|Shanley, Daryl\|Hesketh, John
PMID:	22634395

38.
Journal:	Oncol Rep. 2012 Sep;28(3):949-54.
Title:	Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
Author:	Yu, Chun-Shu\|Huang, An-Cheng\|Lai, Kuang-Chi\|Huang, Yi-Ping\|Lin, Meng-Wei\|Yang, Jai-Sing\|Chung, Jing-Gung
PMID:	22736270

39.
Journal:	Cancer Res. 2012 Dec 15;72(24):6512-23.
Title:	Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer.
Author:	Ren, Shun X\|Cheng, Alfred S L\|To, Ka F\|Tong, Joanna H M\|Li, May S\|Shen, Jing\|Wong, Clover C M\|Zhang, Lin\|Chan, Ruby L Y\|Wang, Xiao J\|Ng, Simon S M\|Chiu, Lawrence C M\|Marquez, Victor E\|Gallo, Richard L\|Chan, Francis K L\|Yu, Jun\|Sung, Joseph J Y\|Wu, William
PMID:	23100468

40.
Journal:	Biochem Biophys Res Commun. 2013 May 10;434(3):634-40.
Title:	Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells.
Author:	Seo, Kang-Sik\|Kim, Hoon\|Hong, Tae-Hwa\|Kim, Jong-Seok\|Song, Kyoung-Sub\|Yun, Eun-Jin\|Park, Ji-Hoon\|Jung, Young-Hoon\|Park, Jong-Il\|Kweon, Gi Ryang\|Yoon, Wan-Hee\|Lim, Kyu\|Hwang, Byung-Doo
PMID:	23583412

41.
Journal:	PLoS One. 2013 May 20;8(5):e63641.
Title:	FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.
Author:	Ren, Shun X\|Shen, Jin\|Cheng, Alfred S L\|Lu, Lan\|Chan, Ruby L Y\|Li, Zhi J\|Wang, Xiao J\|Wong, Clover C M\|Zhang, Lin\|Ng, Simon S M\|Chan, Franky L\|Chan, Francis K L\|Yu, Jun\|Sung, Joseph J Y\|Wu, William K K\|Cho, Chi H
PMID:	23700428

42.
Journal:	Clin Cancer Res. 2013 Jul 15;19(14):3820-31.
Title:	Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy.
Author:	Grassilli, Emanuela\|Narloch, Robert\|Federzoni, Elena\|Ianzano, Leonarda\|Pisano, Fabio\|Giovannoni, Roberto\|Romano, Gabriele\|Masiero, Laura\|Leone, Biagio Eugenio\|Bonin, Serena\|Donada, Marisa\|Stanta, Giorgio\|Helin, Kristian\|Lavitrano, Marialuisa
PMID:	23729362

43.
Journal:	Surgery. 2013 Aug;154(2):143-51.
Title:	Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts.
Author:	Huerta, Sergio\|Gao, Xiaohuan\|Dineen, Sean\|Kapur, Payal\|Saha, Debrabata\|Meyer, Jeffrey
PMID:	23889944

44.
Journal:	PLoS One. 2014 Nov 17;9(11):e113250.
Title:	Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells.
Author:	Ovadje, Pamela\|Ma, Dennis\|Tremblay, Phillip\|Roma, Alessia\|Steckle, Matthew\|Guerrero, Jose-Antonio\|Arnason, John Thor\|Pandey, Siyaram
PMID:	25401766

45.
Journal:	PLoS One. 2014 Jul 1;9(7):e100947.
Title:	GSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosis.
Author:	Grassilli, Emanuela\|Ianzano, Leonarda\|Bonomo, Sara\|Missaglia, Carola\|Cerrito, Maria Grazia\|Giovannoni, Roberto\|Masiero, Laura\|Lavitrano, Marialuisa
PMID:	24984063

46.
Journal:	J Drug Target. 2014 Jul;22(6):543-52.
Title:	Transport and killing mechanism of a novel camptothecin-deoxycholic acid derivate on hepatocellular carcinoma cells.
Author:	Li, Qingyong\|Liu, Tianyu\|Li, Yunchao\|Luo, Shuyue\|Zhu, Qiaochu\|Zhang, Li\|Zhao, Tengfei
PMID:	24725118

47.
Journal:	BMC Cancer. 2014 Mar 1;14:145.
Title:	Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer.
Author:	Agarwal, Ekta\|Chaudhuri, Anathbandhu\|Leiphrakpam, Premila D\|Haferbier, Katie L\|Brattain, Michael G\|Chowdhury, Sanjib
PMID:	24581231

48.
Journal:	Tumour Biol. 2014 Jun;35(6):5307-14.
Title:	Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway.
Author:	Lu, Min\|Sun, Luhaoran\|Zhou, Jin\|Yang, Jing
PMID:	24519064

49.
Journal:	Int J Food Sci Nutr. 2014 May;65(3):368-74.
Title:	Curcumin-enhanced chemosensitivity of FDA-approved platinum (II)-based anti-cancer drugs involves downregulation of nuclear endonuclease G and NF-kappaB as well as induction of apoptosis and G2/M arrest.
Author:	Wang, Ying-Ti\|Liu, Hsiao-Sheng\|Su, Chun-Li
PMID:	24438326

50.
Journal:	Environ Toxicol. 2014 Sep;29(9):969-80.
Title:	Crude extract of Rheum palmatum L induced cell death in LS1034 human colon cancer cells acts through the caspase-dependent and -independent pathways.
Author:	Ma, Yi-Shih\|Hsu, Shu-Chun\|Weng, Shu-Wen\|Yu, Chien-Chih\|Yang, Jai-Sing\|Lai, Kuang-Chi\|Lin, Jing-Pin\|Lin, Jaung-Geng\|Chung, Jing-Gung
PMID:	23315830

51.
Journal:	Strahlenther Onkol. 2014 Sep;190(9):815-22.
Title:	DNA fragmentation and caspase-independent programmed cell death by modulated electrohyperthermia.
Author:	Meggyeshazi, N\|Andocs, G\|Balogh, L\|Balla, P\|Kiszner, G\|Teleki, I\|Jeney, A\|Krenacs, T
PMID:	24562547

52.
Journal:	J Agric Food Chem. 2015 Feb 4;63(4):1142-1150.
Title:	The Tomato Glycoalkaloid alpha-Tomatine Induces Caspase-Independent Cell Death in Mouse Colon Cancer CT-26 Cells and Transplanted Tumors in Mice.
Author:	Kim, Sung Phil\|Nam, Seok Hyun\|Friedman, Mendel
PMID:	25614934

53.
Journal:	PeerJ. 2015 Apr 7;3:e859.
Title:	Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer.
Author:	Runtuwene, Joshua\|Amitani, Haruka\|Amitani, Marie\|Asakawa, Akihiro\|Cheng, Kai-Chun\|Inui, Akio
PMID:	25870767

54.
Journal:	Cancer Cell Int. 2015 Apr 24;15:46.
Title:	Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer.
Author:	Abaza, Mohamed Salah I\|Orabi, Khaled Y\|Al-Quattan, Ebtehal\|Al-Attiyah, Raja'a J
PMID:	26074733

55.
Journal:	Phytomedicine. 2015 Nov 15;22(12):1079-87.
Title:	Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer.
Author:	Wang, Lin\|Hu, Tao\|Shen, Jing\|Zhang, Lin\|Chan, Ruby Lok-Yi\|Lu, Lan\|Li, Mingxing\|Cho, Chi Hin\|Wu, William Ka Kei
PMID:	26547530

56.
Journal:	J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title:	A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author:	Jagadish, Nirmala\|Parashar, Deepak\|Gupta, Namita\|Agarwal, Sumit\|Purohit, Sapna\|Kumar, Vikash\|Sharma, Aditi\|Fatima, Rukhsar\|Topno, Amos Prashant\|Shaha, Chandrima\|Suri, Anil
PMID:	26590805

57.
Journal:	PLoS One. 2016 Feb 9;11(2):e0148775.
Title:	Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author:	Phang, Chung-Weng\|Karsani, Saiful Anuar\|Sethi, Gautam\|Abd Malek, Sri Nurestri
PMID:	26859847

58.
Journal:	Acta Histochem. 2016 Sep;118(7):693-703.
Title:	Apoptotic pathways and stemness in the colorectal epithelium and lamina propria mucosae during the human embryogenesis and carcinogenesis.
Author:	Tica Sedlar, I\|Petricevic, J\|Saraga-Babic, M\|Pintaric, I\|Vukojevic, K
PMID:	27612611

59.
Journal:	Carcinogenesis. 2016 Nov 1;37(11):1079-1088.
Title:	Downregulation of AIF by HIF-1 contributes to hypoxia-induced epithelial-mesenchymal transition of colon cancer.
Author:	Xiong, Zhong\|Guo, Meng\|Yu, Yun\|Zhang, Fei-Fei\|Ge, Meng-Kai\|Chen, Guo-Qiang\|Shen, Shao-Ming
PMID:	27543779

60.
Journal:	Life Sci. 2016 Apr 15;151:224-234.
Title:	Miltirone induced mitochondrial dysfunction and ROS-dependent apoptosis in colon cancer cells.
Author:	Wang, Lin\|Hu, Tao\|Shen, Jing\|Zhang, Lin\|Li, Long-Fei\|Chan, Ruby Lok-Yi\|Li, Ming-Xing\|Wu, William Ka-Kei\|Cho, Chi-Hin
PMID:	26969764

61.
Journal:	Environ Toxicol. 2016 Aug;31(8):957-69.
Title:	Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author:	Lin, Chin-Chung\|Lee, Ming-Huei\|Lin, Ju-Hwa\|Lin, Meng-Liang\|Chueh, Fu-Shin\|Yu, Chien-Chih\|Lin, Jing-Pin\|Chou, Yu-Cheng\|Hsu, Shu-Chun\|Chung, Jing-Gung
PMID:	25689151

62.
Journal:	Oncotarget. 2017 Apr 4;8(14):23603-23612.
Title:	The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.
Author:	Zheng, Hua-Chuan\|Liu, Jia-Jie\|Li, Jing\|Wu, Ji-Cheng\|Yang, Lei\|Zhao, Gui-Feng\|Zhao, Xin\|Jiang, Hua-Mao\|Huang, Ke-Qiang\|Li, Zhi-Jie
PMID:	28223542

63.
Journal:	Oncotarget. 2017 Aug 24;8(47):83207-83224.
Title:	Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells.
Author:	Terzuoli, Erika\|Nannelli, Ginevra\|Frosini, Maria\|Giachetti, Antonio\|Ziche, Marina\|Donnini, Sandra
PMID:	29137335

64.
Journal:	Oncol Rep. 2018 Jan;39(1):61-70.
Title:	Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-alpha-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells.
Author:	Wang, Yu\|Xia, Chunhui\|Lun, Zhiqiang\|Lv, Yanxin\|Chen, Wei\|Li, Tao
PMID:	29115534

65.
Journal:	Acta Pharmacol Sin. 2018 Jun 19. pii: 10.1038/s41401-018-0025-7.
Title:	Annonaceous acetogenin mimic AA005 suppresses human colon cancer cell growth in vivo through downregulation of Mcl-1.
Author:	Han, Bing\|Cao, Yu-Xia\|Li, Zhan-Ming\|Wu, Zhao-Xia\|Mao, Yu-Qin\|Chen, Hui-Ling\|Yao, Zhu-Jun\|Wang, Li-Shun
PMID:	29921883

66.
Journal:	Environ Toxicol. 2018 Sep;33(9):972-977.
Title:	Antitumor activity of RT2 peptide derived from crocodile leukocyte peptide on human colon cancer xenografts in nude mice.
Author:	Maraming, Pornsuda\|Klaynongsruang, Sompong\|Boonsiri, Patcharee\|Maijaroen, Surachai\|Daduang, Sakda\|Chung, Jing-Gung\|Daduang, Jureerut
PMID:	30019842

67.
Journal:	Phytomedicine. 2018 Sep 15;48:152-160.
Title:	Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
Author:	Han, Bing\|Jiang, Pu\|Li, Zhaoxing\|Yu, Yang\|Huang, Tao\|Ye, Xiaoli\|Li, Xuegang
PMID:	30195873