Primary Site >> Colorectal Cancer
Gene >> AHR
| 1. | |||||||||||
| Journal: | Biochem Pharmacol. 1998 Sep 1;56(5):599-612. | ||||||||||
| Title: | Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells: CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene. | ||||||||||
| Author: | Li, W|Harper, P A|Tang, B K|Okey, A B | ||||||||||
| PMID: | 9783729 | ||||||||||
| 2. | |||||||||||
| Journal: | Toxicol Sci. 2003 Apr;72(2):253-9. Epub 2003 Mar 7. | ||||||||||
| Title: | Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines. | ||||||||||
| Author: | Tsuchiya, Yuki|Nakajima, Miki|Itoh, Satsuki|Iwanari, Masashi|Yokoi, Tsuyoshi | ||||||||||
| PMID: | 12655030 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biochem. 2003 May;133(5):583-92. | ||||||||||
| Title: | Critical enhancer region to which AhR/ARNT and Sp1 bind in the human CYP1B1 gene. | ||||||||||
| Author: | Tsuchiya, Yuki|Nakajima, Miki|Yokoi, Tsuyoshi | ||||||||||
| PMID: | 12801909 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Detect Prev. 2005;29(6):562-9. Epub 2005 Nov 10. | ||||||||||
| Title: | Using a combination of cytochrome P450 1B1 and beta-catenin for early diagnosis and prevention of colorectal cancer. | ||||||||||
| Author: | Chang, Han|Su, Jang-Ming|Huang, Chee C|Liu, Lan C|Tsai, Chung H|Chou, Ming-Chih|Lin, Pinpin | ||||||||||
| PMID: | 16289386 | ||||||||||
| 5. | |||||||||||
| Journal: | Drug Metab Dispos. 2006 Jul;34(7):1096-101. Epub 2006 Mar 31. | ||||||||||
| Title: | Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone. | ||||||||||
| Author: | Schreiber, Thomas D|Kohle, Christoph|Buckler, Felicitas|Schmohl, Stefan|Braeuning, Albert|Schmiechen, Alexander|Schwarz, Michael|Munzel, Peter A | ||||||||||
| PMID: | 16581943 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3098-107. | ||||||||||
| Title: | Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. | ||||||||||
| Author: | Cotterchio, Michelle|Boucher, Beatrice A|Manno, Michael|Gallinger, Steven|Okey, Allan B|Harper, Patricia A | ||||||||||
| PMID: | 18990750 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Oncol. 2009 Apr;34(4):1085-91. | ||||||||||
| Title: | CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. | ||||||||||
| Author: | Habano, Wataru|Gamo, Toshie|Sugai, Tamotsu|Otsuka, Koki|Wakabayashi, Go|Ozawa, Shogo | ||||||||||
| PMID: | 19287966 | ||||||||||
| 8. | |||||||||||
| Journal: | PLoS One. 2009;4(4):e5130. | ||||||||||
| Title: | Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. | ||||||||||
| Author: | Hashimoto, Yosuke|Loftis, David W|Adams, Josephine C | ||||||||||
| PMID: | 19340314 | ||||||||||
| 9. | |||||||||||
| Journal: | Biol Pharm Bull. 2010;33(10):1650-7. | ||||||||||
| Title: | Bi-functional induction of the quinone reductase and cytochrome P450 1A1 by youngiasides via Nrf2-ARE and AhR-XRE pathways. | ||||||||||
| Author: | Yun, Ji Ho|Lee, Saet Byoul|Lee, Hee Ju|Kim, Chul Young|Kim, Mi Ae|Sohn, Young Chang|Nho, Chu Won | ||||||||||
| PMID: | 20930371 | ||||||||||
| 10. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2010 Nov;335(2):273-83. | ||||||||||
| Title: | Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity. | ||||||||||
| Author: | Perdew, Gary H|Hollingshead, Brett D|Dinatale, Brett C|Morales, J Luis|Labrecque, Mark P|Takhar, Mandeep K|Tam, Kevin J|Beischlag, Timothy V | ||||||||||
| PMID: | 20716622 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Pharmacol. 2010 Aug;78(2):175-85. | ||||||||||
| Title: | Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2). | ||||||||||
| Author: | Tan, Kah Poh|Wang, Bernice|Yang, Mingdong|Boutros, Paul C|Macaulay, Jane|Xu, Haibo|Chuang, Andrew I|Kosuge, Kazuhiro|Yamamoto, Mika|Takahashi, Shinichiro|Wu, Alex M L|Ross, Douglas D|Harper, Patricia A|Ito, Shinya | ||||||||||
| PMID: | 20460431 | ||||||||||
| 12. | |||||||||||
| Journal: | Drug Metab Rev. 2010 Feb;42(1):6-13. | ||||||||||
| Title: | UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor-inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors. | ||||||||||
| Author: | Bock, Karl W|Bock-Hennig, Barbara S | ||||||||||
| PMID: | 19831498 | ||||||||||
| 13. | |||||||||||
| Journal: | Carcinogenesis. 2011 Feb;32(2):203-9. | ||||||||||
| Title: | Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. | ||||||||||
| Author: | Wang, Hansong|Yamamoto, Jennifer F|Caberto, Christian|Saltzman, Barbara|Decker, Robert|Vogt, Thomas M|Yokochi, Lance|Chanock, Stephen|Wilkens, Lynne R|Le Marchand, Loic | ||||||||||
| PMID: | 21081473 | ||||||||||
| 14. | |||||||||||
| Journal: | Toxicol In Vitro. 2011 Apr;25(3):671-83. | ||||||||||
| Title: | Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. | ||||||||||
| Author: | Niestroy, Jeanette|Barbara, Alfonso|Herbst, Kathrin|Rode, Sandra|van Liempt, Manuela|Roos, Peter H | ||||||||||
| PMID: | 21256954 | ||||||||||
| 15. | |||||||||||
| Journal: | Dig Dis Sci. 2011 Sep;56(9):2532-44. | ||||||||||
| Title: | A role of the aryl hydrocarbon receptor in attenuation of colitis. | ||||||||||
| Author: | Furumatsu, Keisuke|Nishiumi, Shin|Kawano, Yuki|Ooi, Makoto|Yoshie, Tomoo|Shiomi, Yuuki|Kutsumi, Hiromu|Ashida, Hitoshi|Fujii-Kuriyama, Yoshiaki|Azuma, Takeshi|Yoshida, Masaru | ||||||||||
| PMID: | 21374063 | ||||||||||
| 16. | |||||||||||
| Journal: | Toxicol Lett. 2011 Jun 24;203(3):258-64. | ||||||||||
| Title: | Epigallocatechin-3-gallate does not affect the activity of enzymes involved in metabolic activation and cellular excretion of benzo[a]pyrene in human colon carcinoma cells. | ||||||||||
| Author: | Bothe, Hanno|Gassmann, Kathrin|Gotz, Christine|Fritsche, Ellen|Abel, Josef|Haarmann-Stemmann, Thomas | ||||||||||
| PMID: | 21458546 | ||||||||||
| 17. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G1006-15. | ||||||||||
| Title: | Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation. | ||||||||||
| Author: | Xie, Guofeng|Peng, Zhongsheng|Raufman, Jean-Pierre | ||||||||||
| PMID: | 22361730 | ||||||||||
| 18. | |||||||||||
| Journal: | Carcinogenesis. 2012 Jul;33(7):1332-9. | ||||||||||
| Title: | Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer. | ||||||||||
| Author: | Gilsing, Anne M J|Berndt, Sonja I|Ruder, Elizabeth H|Graubard, Barry I|Ferrucci, Leah M|Burdett, Laura|Weissfeld, Joel L|Cross, Amanda J|Sinha, Rashmi | ||||||||||
| PMID: | 22552404 | ||||||||||
| 19. | |||||||||||
| Journal: | Arch Toxicol. 2013 Apr;87(4):633-43. | ||||||||||
| Title: | The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol. | ||||||||||
| Author: | Kluxen, Felix M|Diel, Patrick|Hofer, Nicola|Becker, Eugenia|Degen, Gisela H | ||||||||||
| PMID: | 23135549 | ||||||||||
| 20. | |||||||||||
| Journal: | J Cell Biochem. 2013 Oct;114(10):2392-404. | ||||||||||
| Title: | Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer. | ||||||||||
| Author: | Callero, Mariana A|Luzzani, Gabriela A|De Dios, Diana O|Bradshaw, Tracey D|Perez, Andrea I Loaiza | ||||||||||
| PMID: | 23696052 | ||||||||||
| 21. | |||||||||||
| Journal: | Food Funct. 2014 Jun;5(6):1073-81. | ||||||||||
| Title: | Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently. | ||||||||||
| Author: | Lippmann, Doris|Lehmann, Carsten|Florian, Simone|Barknowitz, Gitte|Haack, Michael|Mewis, Inga|Wiesner, Melanie|Schreiner, Monika|Glatt, Hansruedi|Brigelius-Flohe, Regina|Kipp, Anna P | ||||||||||
| PMID: | 24714741 | ||||||||||
| 22. | |||||||||||
| Journal: | PLoS One. 2014 Oct 21;9(10):e110134. | ||||||||||
| Title: | Integrated exon level expression analysis of driver genes explain their role in colorectal cancer. | ||||||||||
| Author: | Aziz, Mohammad Azhar|Periyasamy, Sathish|Al Yousef, Zeyad|AlAbdulkarim, Ibrahim|Al Otaibi, Majed|Alfahed, Abdulaziz|Alasiri, Glowi | ||||||||||
| PMID: | 25335079 | ||||||||||
| 23. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2015 Jan 1;282(1):30-41. | ||||||||||
| Title: | Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer. | ||||||||||
| Author: | Spink, Barbara C|Bloom, Michael S|Wu, Susan|Sell, Stewart|Schneider, Erasmus|Ding, Xinxin|Spink, David C | ||||||||||
| PMID: | 25447411 | ||||||||||
| 24. | |||||||||||
| Journal: | Drug Metab Dispos. 2015 Oct;43(10):1536-43. | ||||||||||
| Title: | Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes. | ||||||||||
| Author: | Cheng, Yating|Jin, Un-Ho|Allred, Clint D|Jayaraman, Arul|Chapkin, Robert S|Safe, Stephen | ||||||||||
| PMID: | 25873348 | ||||||||||
| 25. | |||||||||||
| Journal: | Dis Model Mech. 2015 Sep;8(9):1093-103. | ||||||||||
| Title: | HIF1alpha deficiency reduces inflammation in a mouse model of proximal colon cancer. | ||||||||||
| Author: | Mladenova, Dessislava N|Dahlstrom, Jane E|Tran, Phuong N|Benthani, Fahad|Bean, Elaine G|Ng, Irvin|Pangon, Laurent|Currey, Nicola|Kohonen-Corish, Maija R J | ||||||||||
| PMID: | 26183215 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancers (Basel). 2015 Jul 31;7(3):1436-46. | ||||||||||
| Title: | Role of the Aryl Hydrocarbon Receptor in Colon Neoplasia. | ||||||||||
| Author: | Xie, Guofeng|Raufman, Jean-Pierre | ||||||||||
| PMID: | 26264025 | ||||||||||
| 27. | |||||||||||
| Journal: | Ann Surg. 2016 Sep;264(3):429-36. | ||||||||||
| Title: | The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse. | ||||||||||
| Author: | Diaz-Diaz, Carol J|Ronnekleiv-Kelly, Sean M|Nukaya, Manabu|Geiger, Peter G|Balbo, Silvia|Dator, Romel|Megna, Bryant W|Carney, Patrick R|Bradfield, Christopher A|Kennedy, Gregory D | ||||||||||
| PMID: | 27433903 | ||||||||||
| 28. | |||||||||||
| Journal: | Srp Arh Celok Lek. 2016 May-Jun;144(5-6):334-8. | ||||||||||
| Title: | Anorectal melanoma and seborrheic dermatitis - A case report. | ||||||||||
| Author: | Vekic, Berislav|Zivic, Rastko|Kalezic, Marko|Otasevic, Suzana|Arsic-Arsenijevic, Valentina | ||||||||||
| PMID: | 29648758 | ||||||||||
| 29. | |||||||||||
| Journal: | J Surg Res. 2016 Jul;204(1):47-54. | ||||||||||
| Title: | Indole-3-carbinol induces tumor cell death: function follows form. | ||||||||||
| Author: | Megna, Bryant W|Carney, Patrick R|Nukaya, Manabu|Geiger, Pete|Kennedy, Gregory D | ||||||||||
| PMID: | 27451867 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2016 Aug;65(8):919-29. | ||||||||||
| Title: | Regulation of CD40 signaling in colon cancer cells and its implications in clinical tissues. | ||||||||||
| Author: | Zhou, Yan|Zhou, Shu-Xian|Gao, Long|Li, Xiao-An | ||||||||||
| PMID: | 27262846 | ||||||||||
| 31. | |||||||||||
| Journal: | Exp Cell Res. 2016 May 1;343(2):126-134. | ||||||||||
| Title: | Tissue distribution of aryl hydrocarbon receptor in the intestine: Implication of putative roles in tumor suppression. | ||||||||||
| Author: | Ikuta, Togo|Kurosumi, Masafumi|Yatsuoka, Toshimasa|Nishimura, Yoji | ||||||||||
| PMID: | 26973338 | ||||||||||
| 32. | |||||||||||
| Journal: | Cell Biol Int. 2016 May;40(5):560-8. | ||||||||||
| Title: | The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins. | ||||||||||
| Author: | Yin, Jiuheng|Sheng, Baifa|Han, Bin|Pu, Aimin|Yang, Kunqiu|Li, Ping|Wang, Qimeng|Xiao, Weidong|Yang, Hua | ||||||||||
| PMID: | 26861731 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Lett. 2016 Jan 1;370(1):91-9. | ||||||||||
| Title: | Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells. | ||||||||||
| Author: | Ronnekleiv-Kelly, Sean M|Nukaya, Manabu|Diaz-Diaz, Carol J|Megna, Bryant W|Carney, Patrick R|Geiger, Peter G|Kennedy, Gregory D | ||||||||||
| PMID: | 26515162 | ||||||||||
| 34. | |||||||||||
| Journal: | Dig Dis Sci. 2016 Feb;61(2):444-52. | ||||||||||
| Title: | Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells. | ||||||||||
| Author: | Yin, Jiuheng|Sheng, Baifa|Pu, Aimin|Han, Bin|Yang, Kunqiu|Wang, Qimeng|Sun, Lihua|Yang, Hua | ||||||||||
| PMID: | 26514676 | ||||||||||
| 35. | |||||||||||
| Journal: | Arch Toxicol. 2017 Feb;91(2):967-982. | ||||||||||
| Title: | The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation. | ||||||||||
| Author: | Faust, Dagmar|Nikolova, Teodora|Watjen, Wim|Kaina, Bernd|Dietrich, Cornelia | ||||||||||
| PMID: | 26856715 | ||||||||||
| 36. | |||||||||||
| Journal: | Toxicol Sci. 2017 Feb;155(2):458-473. | ||||||||||
| Title: | Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. | ||||||||||
| Author: | Cheng, Yating|Jin, Un-Ho|Davidson, Laurie A|Chapkin, Robert S|Jayaraman, Arul|Tamamis, Phanourios|Orr, Asuka|Allred, Clint|Denison, Michael S|Soshilov, Anatoly|Weaver, Evelyn|Safe, Stephen | ||||||||||
| PMID: | 27837168 | ||||||||||
| 37. | |||||||||||
| Journal: | Sci Rep. 2017 Aug 31;7(1):10163. | ||||||||||
| Title: | Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells. | ||||||||||
| Author: | Jin, Un-Ho|Cheng, Yating|Park, Hyejin|Davidson, Laurie A|Callaway, Evelyn S|Chapkin, Robert S|Jayaraman, Arul|Asante, Andrew|Allred, Clinton|Weaver, Evelyn A|Safe, Stephen | ||||||||||
| PMID: | 28860561 | ||||||||||
| 38. | |||||||||||
| Journal: | BMC Cancer. 2017 Dec 13;17(1):848. | ||||||||||
| Title: | Family history of prostate and colorectal cancer and risk of colorectal cancer in the Women's health initiative. | ||||||||||
| Author: | Beebe-Dimmer, Jennifer L|Yee, Cecilia|Paskett, Electra|Schwartz, Ann G|Lane, Dorothy|Palmer, Nynikka R A|Bock, Cathryn H|Nassir, Rami|Simon, Michael S | ||||||||||
| PMID: | 29237415 | ||||||||||
| 39. | |||||||||||
| Journal: | Oncol Rep. 2018 Apr;39(4):1930-1938. | ||||||||||
| Title: | Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals. | ||||||||||
| Author: | Park, Joo-Hung|Lee, Jeong-Min|Lee, Eun-Jin|Kim, Da-Jeong|Hwang, Won-Bhin | ||||||||||
| PMID: | 29436668 | ||||||||||
| 40. | |||||||||||
| Journal: | EBioMedicine. 2018 Apr;30:14-28. | ||||||||||
| Title: | Obesity and Cancer: Existing and New Hypotheses for a Causal Connection. | ||||||||||
| Author: | Stone, Trevor W|McPherson, Megan|Gail Darlington, L | ||||||||||
| PMID: | 29526577 | ||||||||||
| 41. | |||||||||||
| Journal: | Toxicol Sci. 2018 Jul 1;164(1):205-217. | ||||||||||
| Title: | Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids. | ||||||||||
| Author: | Jin, Un-Ho|Park, Hyejin|Li, Xi|Davidson, Laurie A|Allred, Clinton|Patil, Bhimanagouda|Jayaprakasha, Guddadarangavva|Orr, Asuka A|Mao, Leevin|Chapkin, Robert S|Jayaraman, Arul|Tamamis, Phanourios|Safe, Stephen | ||||||||||
| PMID: | 29584932 | ||||||||||