Primary Site >> Pancreatic Cancer

Gene >> AGR2

Journal: Cancer Res. 2008 Oct 1;68(19):7811-8.
Title: Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival.
Author: Ramachandran, Vijaya|Arumugam, Thiruvengadam|Wang, Huamin|Logsdon, Craig D
PMID: 18829536
Journal: Histol Histopathol. 2009 Sep;24(9):1121-8.
Title: Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma.
Author: Riener, Marc-Oliver|Pilarsky, Christian|Gerhardt, Josefine|Grutzmann, Robert|Fritzsche, Florian R|Bahra, Marcus|Weichert, Wilko|Kristiansen, Glen
PMID: 19609859
Journal: Mol Cancer. 2010 Jun 15;9:149.
Title: Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia.
Author: Chen, Ru|Pan, Sheng|Duan, Xiaobo|Nelson, Brad H|Sahota, Rob A|de Rham, Sarah|Kozarek, Richard A|McIntosh, Martin|Brentnall, Teresa A
PMID: 20550709
Journal: Liver Int. 2011 Mar;31(3):322-8.
Title: Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree.
Author: Lepreux, Sebastien|Bioulac-Sage, Paulette|Chevet, Eric
PMID: 21281432
Journal: Cancer Res. 2011 Nov 15;71(22):7091-102.
Title: AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D.
Author: Dumartin, Laurent|Whiteman, Hannah J|Weeks, Mark E|Hariharan, Deepak|Dmitrovic, Branko|Iacobuzio-Donahue, Christine A|Brentnall, Teresa A|Bronner, Mary P|Feakins, Roger M|Timms, John F|Brennan, Caroline|Lemoine, Nicholas R|Crnogorac-Jurcevic, Tatjana
PMID: 21948970
Journal: Oncogene. 2013 Aug 15;32(33):3867-76.
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Author: Norris, A M|Gore, A|Balboni, A|Young, A|Longnecker, D S|Korc, M
PMID: 22945649
Journal: Clin Exp Metastasis. 2013 Mar;30(3):251-64.
Title: S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells.
Author: Barry, Sayka|Chelala, Claude|Lines, Kate|Sunamura, Makoto|Wang, Amu|Marelli-Berg, Federica M|Brennan, Caroline|Lemoine, Nicholas R|Crnogorac-Jurcevic, Tatjana
PMID: 23007696
Journal: BMC Cancer. 2013 Sep 3;13:404.
Title: Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9.
Author: Makawita, Shalini|Dimitromanolakis, Apostolos|Soosaipillai, Antoninus|Soleas, Ireena|Chan, Alison|Gallinger, Steven|Haun, Randy S|Blasutig, Ivan M|Diamandis, Eleftherios P
PMID: 24007603
Journal: Br J Cancer. 2014 Sep 9;111(6):1139-49.
Title: Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.
Author: Souchek, J J|Baine, M J|Lin, C|Rachagani, S|Gupta, S|Kaur, S|Lester, K|Zheng, D|Chen, S|Smith, L|Lazenby, A|Johansson, S L|Jain, M|Batra, S K
PMID: 25025965
Journal: Tohoku J Exp Med. 2014 Sep;234(1):83-8.
Title: Expression of anterior gradient 2 is decreased with the progression of human biliary tract cancer.
Author: Kim, Su Jin|Kim, Dong Hoon|Kang, Dongchul|Kim, Jong Hyeok
PMID: 25186196
Journal: Pancreas. 2014 Jan;43(1):75-81.
Title: Anterior gradient 2 and mucin 4 expression mirrors tumor cell differentiation in pancreatic adenocarcinomas, but aberrant anterior gradient 2 expression predicts worse patient outcome in poorly differentiated tumors.
Author: Brychtova, Veronika|Hermanova, Marketa|Karasek, Petr|Lenz, Jiri|Selingerova, Iveta|Vojtesek, Borivoj|Kala, Zdenek|Hrstka, Roman
PMID: 24177142
Journal: Lab Invest. 2015 Feb;95(2):193-206.
Title: Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
Author: Mizuuchi, Yusuke|Aishima, Shinichi|Ohuchida, Kenoki|Shindo, Koji|Fujino, Minoru|Hattori, Masami|Miyazaki, Tetsuyuki|Mizumoto, Kazuhiro|Tanaka, Masao|Oda, Yoshinao
PMID: 25418581
Journal: Mol Cancer Ther. 2015 Apr;14(4):941-51.
Title: New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice.
Author: Arumugam, Thiruvengadam|Deng, Defeng|Bover, Laura|Wang, Huamin|Logsdon, Craig D|Ramachandran, Vijaya
PMID: 25646014
Journal: Oncotarget. 2016 Jul 19;7(29):45547-45561.
Title: MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis.
Author: Tu, Mei-Juan|Pan, Yu-Zhuo|Qiu, Jing-Xin|Kim, Edward J|Yu, Ai-Ming
PMID: 27322206
Journal: PLoS One. 2016 Oct 20;11(10):e0164968.
Title: Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration.
Author: Wodziak, Dariusz|Dong, Aiwen|Basin, Michael F|Lowe, Anson W
PMID: 27764193
Journal: Oncogene. 2017 Jun 1;36(22):3094-3103.
Title: ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.
Author: Dumartin, L|Alrawashdeh, W|Trabulo, S M|Radon, T P|Steiger, K|Feakins, R M|di Magliano, M P|Heeschen, C|Esposito, I|Lemoine, N R|Crnogorac-Jurcevic, T
PMID: 27941872
Journal: Pancreatology. 2018 Jun;18(4):407-412.
Title: Clinicopathological and prognostic significance of MUC13 and AGR2 expression in intraductal papillary mucinous neoplasms of the pancreas.
Author: Mito, Kumiko|Saito, Michihiro|Morita, Kohei|Maetani, Iruru|Sata, Naohiro|Mieno, Makiko|Fukushima, Noriyoshi
PMID: 29650332
Journal: Pancreatology. 2018 Sep;18(6):678-688.
Title: Knockdown of AGR2 induces cell apoptosis and reduces chemotherapy resistance of pancreatic cancer cells with the involvement of ERK/AKT axis.
Author: Liu, Qing-Guo|Li, Yan-Ju|Yao, Lan
PMID: 30055941