Primary Site >> Pancreatic Cancer
Gene >> AGR2
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Ref: Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival. PMID: 18829536 |
Ref: Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma. PMID: 19609859 |
Ref: Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia. PMID: 20550709 |
Ref: Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree. PMID: 21281432 Ref: AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D. PMID: 21948970 |
Ref: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. PMID: 22945649 Ref: S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells. PMID: 23007696 Ref: Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9. PMID: 24007603 |
Ref: Anterior gradient 2 and mucin 4 expression mirrors tumor cell differentiation in pancreatic adenocarcinomas, but aberrant anterior gradient 2 expression predicts worse patient outcome in poorly differentiated tumors. PMID: 24177142 Ref: Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation. PMID: 25025965 Ref: Expression of anterior gradient 2 is decreased with the progression of human biliary tract cancer. PMID: 25186196 |
Ref: Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition. PMID: 25418581 Ref: New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice. PMID: 25646014 |
Ref: MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis. PMID: 27322206 Ref: Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration. PMID: 27764193 |
Ref: ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation. PMID: 27941872 |
Ref: Clinicopathological and prognostic significance of MUC13 and AGR2 expression in intraductal papillary mucinous neoplasms of the pancreas. PMID: 29650332 Ref: Knockdown of AGR2 induces cell apoptosis and reduces chemotherapy resistance of pancreatic cancer cells with the involvement of ERK/AKT axis. PMID: 30055941 |