Primary Site >> Colorectal Cancer
Gene >> ACVR2A
| 1. | |||||||||||
| Journal: | Gut. 2001 Sep;49(3):409-17. | ||||||||||
| Title: | Overexpression of activin A in stage IV colorectal cancer. | ||||||||||
| Author: | Wildi, S|Kleeff, J|Maruyama, H|Maurer, C A|Buchler, M W|Korc, M | ||||||||||
| PMID: | 11511564 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2001 Aug 15;61(16):6046-9. | ||||||||||
| Title: | Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. | ||||||||||
| Author: | Mori, Y|Yin, J|Rashid, A|Leggett, B A|Young, J|Simms, L|Kuehl, P M|Langenberg, P|Meltzer, S J|Stine, O C | ||||||||||
| PMID: | 11507051 | ||||||||||
| 3. | |||||||||||
| Journal: | Lab Invest. 2003 Dec;83(12):1867-71. | ||||||||||
| Title: | Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors. | ||||||||||
| Author: | Olaru, Andreea|Mori, Yuriko|Yin, Jing|Wang, Suna|Kimos, Martha C|Perry, Kellie|Xu, Yan|Sato, Fumiaki|Selaru, Florin M|Deacu, Elena|Sterian, Anca|Shibata, David|Abraham, John M|Meltzer, Stephen J | ||||||||||
| PMID: | 14691305 | ||||||||||
| 4. | |||||||||||
| Journal: | Gastroenterology. 2004 Mar;126(3):654-9. | ||||||||||
| Title: | Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers. | ||||||||||
| Author: | Jung, Barbara|Doctolero, Ryan T|Tajima, Akihiro|Nguyen, Alexie K|Keku, Temitope|Sandler, Robert S|Carethers, John M | ||||||||||
| PMID: | 14988818 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2004 Nov 1;64(21):7690-6. | ||||||||||
| Title: | Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes. | ||||||||||
| Author: | Deacu, Elena|Mori, Yuriko|Sato, Fumiaki|Yin, Jing|Olaru, Andreea|Sterian, Anca|Xu, Yan|Wang, Suna|Schulmann, Karsten|Berki, Agnes|Kan, Takatsugu|Abraham, John M|Meltzer, Stephen J | ||||||||||
| PMID: | 15520171 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Cancer. 2006 May 15;118(10):2509-13. | ||||||||||
| Title: | Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers. | ||||||||||
| Author: | Jung, Barbara|Smith, E Julieta|Doctolero, Ryan T|Gervaz, Pascal|Alonso, Julio C|Miyai, Katsumi|Keku, Temitope|Sandler, Robert S|Carethers, John M | ||||||||||
| PMID: | 16380996 | ||||||||||
| 7. | |||||||||||
| Journal: | Dis Colon Rectum. 2006 Mar;49(3):399-406. | ||||||||||
| Title: | Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer. | ||||||||||
| Author: | Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko | ||||||||||
| PMID: | 16421660 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28. | ||||||||||
| Title: | Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells. | ||||||||||
| Author: | Grijelmo, Clara|Rodrigue, Christelle|Svrcek, Magalie|Bruyneel, Erik|Hendrix, An|de Wever, Olivier|Gespach, Christian | ||||||||||
| PMID: | 17478078 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Endocrinol. 2007 Oct;21(10):2458-71. Epub 2007 Jul 3. | ||||||||||
| Title: | Intraovarian activins are required for female fertility. | ||||||||||
| Author: | Pangas, Stephanie A|Jorgez, Carolina J|Tran, Mai|Agno, Julio|Li, Xiaohui|Brown, Chester W|Kumar, T Rajendra|Matzuk, Martin M | ||||||||||
| PMID: | 17609433 | ||||||||||
| 10. | |||||||||||
| Journal: | Gastroenterology. 2007 Feb;132(2):633-44. Epub 2006 Nov 16. | ||||||||||
| Title: | Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin. | ||||||||||
| Author: | Jung, Barbara H|Beck, Stayce E|Cabral, Jennifer|Chau, Eddy|Cabrera, Betty L|Fiorino, Antonio|Smith, E Julieta|Bocanegra, Melanie|Carethers, John M | ||||||||||
| PMID: | 17258738 | ||||||||||
| 11. | |||||||||||
| Journal: | Glycobiology. 2009 Jul;19(7):726-34. | ||||||||||
| Title: | Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile. | ||||||||||
| Author: | Patsos, Georgios|Andre, Sabine|Roeckel, Nina|Gromes, Roland|Gebert, Johannes|Kopitz, Jurgen|Gabius, Hans-Joachim | ||||||||||
| PMID: | 19293232 | ||||||||||
| 12. | |||||||||||
| Journal: | Mod Pathol. 2009 Sep;22(9):1186-95. | ||||||||||
| Title: | Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations. | ||||||||||
| Author: | Tougeron, David|Fauquembergue, Emilie|Rouquette, Alexandre|Le Pessot, Florence|Sesboue, Richard|Laurent, Michele|Berthet, Pascaline|Mauillon, Jacques|Di Fiore, Frederic|Sabourin, Jean-Christophe|Michel, Pierre|Tosi, Mario|Frebourg, Thierry|Latouche, Jean- | ||||||||||
| PMID: | 19503063 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2009 Dec 14;4(12):e8308. | ||||||||||
| Title: | Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms. | ||||||||||
| Author: | Jung, Barbara|Gomez, Jessica|Chau, Eddy|Cabral, Jennifer|Lee, Jeffrey K|Anselm, Aimee|Slowik, Przemyslaw|Ream-Robinson, Deena|Messer, Karen|Sporn, Judith|Shin, Sung K|Boland, C Richard|Goel, Ajay|Carethers, John M | ||||||||||
| PMID: | 20011542 | ||||||||||
| 14. | |||||||||||
| Journal: | Nucleic Acids Res. 2010 Jan;38(Database issue):D682-9. | ||||||||||
| Title: | SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology. | ||||||||||
| Author: | Woerner, Stefan M|Yuan, Yan P|Benner, Axel|Korff, Sebastian|von Knebel Doeberitz, Magnus|Bork, Peer | ||||||||||
| PMID: | 19820113 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Carcinog. 2010 Feb;49(2):175-82. | ||||||||||
| Title: | Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation. | ||||||||||
| Author: | Michel, Sara|Kloor, Matthias|Singh, Sandhya|Gdynia, Georg|Roth, Wilfried|von Knebel Doeberitz, Magnus|Schirmacher, Peter|Blaker, Hendrik | ||||||||||
| PMID: | 19852062 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Cancer. 2012 Apr 1;130(7):1558-66. | ||||||||||
| Title: | Candidate driver genes in microsatellite-unstable colorectal cancer. | ||||||||||
| Author: | Alhopuro, Pia|Sammalkorpi, Heli|Niittymaki, Iina|Bistrom, Mia|Raitila, Anniina|Saharinen, Juha|Nousiainen, Kari|Lehtonen, Heli J|Heliovaara, Elina|Puhakka, Jani|Tuupanen, Sari|Sousa, Sonia|Seruca, Raquel|Ferreira, Ana M|Hofstra, Robert M W|Mecklin, Jukka- | ||||||||||
| PMID: | 21544814 | ||||||||||
| 17. | |||||||||||
| Journal: | Nature. 2012 Jul 18;487(7407):330-7. | ||||||||||
| Title: | Comprehensive molecular characterization of human colon and rectal cancer. | ||||||||||
| Author: | |||||||||||
| PMID: | 22810696 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2012;7(6):e39381. | ||||||||||
| Title: | Effects of activin and TGFbeta on p21 in colon cancer. | ||||||||||
| Author: | Bauer, Jessica|Sporn, Judith C|Cabral, Jennifer|Gomez, Jessica|Jung, Barbara | ||||||||||
| PMID: | 22761777 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2013 May 21;8(5):e64271. | ||||||||||
| Title: | Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing. | ||||||||||
| Author: | Han, Sae-Won|Kim, Hwang-Phill|Shin, Jong-Yeon|Jeong, Eun-Goo|Lee, Won-Chul|Lee, Kyung-Hun|Won, Jae-Kyung|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Park, Jae-Gahb|Kang, Gyeong Hoon|Seo, Jeong-Sun|Kim, Jong-Il|Kim | ||||||||||
| PMID: | 23700467 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Res. 2014 Jun 15;74(12):3238-47. | ||||||||||
| Title: | Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer. | ||||||||||
| Author: | Mouradov, Dmitri|Sloggett, Clare|Jorissen, Robert N|Love, Christopher G|Li, Shan|Burgess, Antony W|Arango, Diego|Strausberg, Robert L|Buchanan, Daniel|Wormald, Samuel|O'Connor, Liam|Wilding, Jennifer L|Bicknell, David|Tomlinson, Ian P M|Bodmer, Walter F|M | ||||||||||
| PMID: | 24755471 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Cell Proteomics. 2014 Dec;13(12):3446-56. | ||||||||||
| Title: | De Novo proteome analysis of genetically modified tumor cells by a metabolic labeling/azide-alkyne cycloaddition approach. | ||||||||||
| Author: | Ballikaya, Seda|Lee, Jennifer|Warnken, Uwe|Schnolzer, Martina|Gebert, Johannes|Kopitz, Jurgen | ||||||||||
| PMID: | 25225355 | ||||||||||
| 22. | |||||||||||
| Journal: | Arch Toxicol. 2015 Jun;89(6):899-921. | ||||||||||
| Title: | Microsatellite instability: an update. | ||||||||||
| Author: | Yamamoto, Hiroyuki|Imai, Kohzoh | ||||||||||
| PMID: | 25701956 | ||||||||||
| 23. | |||||||||||
| Journal: | Gastroenterology. 2015 Jun;148(7):1427-37.e8. | ||||||||||
| Title: | Transforming Growth Factor beta Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2. | ||||||||||
| Author: | de Miranda, Noel F C C|van Dinther, Maarten|van den Akker, Brendy E W M|van Wezel, Tom|ten Dijke, Peter|Morreau, Hans | ||||||||||
| PMID: | 25736321 | ||||||||||
| 24. | |||||||||||
| Journal: | Am J Surg Pathol. 2015 Aug;39(8):1140-7. | ||||||||||
| Title: | Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer. | ||||||||||
| Author: | Jesinghaus, Moritz|Wolf, Thomas|Pfarr, Nicole|Muckenhuber, Alexander|Ahadova, Aysel|Warth, Arne|Goeppert, Benjamin|Sers, Christine|Kloor, Matthias|Endris, Volker|Stenzinger, Albrecht|Weichert, Wilko | ||||||||||
| PMID: | 25786087 | ||||||||||
| 25. | |||||||||||
| Journal: | Br J Cancer. 2015 Aug 11;113(4):686-92. | ||||||||||
| Title: | Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation. | ||||||||||
| Author: | Pinheiro, Manuela|Pinto, Carla|Peixoto, Ana|Veiga, Isabel|Lopes, Paula|Henrique, Rui|Baldaia, Helena|Carneiro, Fatima|Seruca, Raquel|Tomlinson, Ian|Kovac, Michal|Heinimann, Karl|Teixeira, Manuel R | ||||||||||
| PMID: | 26247575 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 29;6(29):27725-35. | ||||||||||
| Title: | Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinoma. | ||||||||||
| Author: | Kim, Tae-Min|An, Chang Hyeok|Rhee, Je-Keun|Jung, Seung-Hyun|Lee, Sung Hak|Baek, In-Pyo|Kim, Min Sung|Lee, Sug Hyung|Chung, Yeun-Jun | ||||||||||
| PMID: | 26336987 | ||||||||||
| 27. | |||||||||||
| Journal: | Mol Cancer. 2015 Oct 24;14:182. | ||||||||||
| Title: | Activin and TGFbeta use diverging mitogenic signaling in advanced colon cancer. | ||||||||||
| Author: | Bauer, Jessica|Ozden, Ozkan|Akagi, Naomi|Carroll, Timothy|Principe, Daniel R|Staudacher, Jonas J|Spehlmann, Martina E|Eckmann, Lars|Grippo, Paul J|Jung, Barbara | ||||||||||
| PMID: | 26497569 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Cell. 2016 Feb 8;29(2):229-40. | ||||||||||
| Title: | Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma. | ||||||||||
| Author: | Yachida, Shinichi|Wood, Laura D|Suzuki, Masami|Takai, Erina|Totoki, Yasushi|Kato, Mamoru|Luchini, Claudio|Arai, Yasuhito|Nakamura, Hiromi|Hama, Natsuko|Elzawahry, Asmaa|Hosoda, Fumie|Shirota, Tomoki|Morimoto, Nobuhiko|Hori, Kunio|Funazaki, Jun|Tanaka, Hik | ||||||||||
| PMID: | 26806338 | ||||||||||
| 29. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2016 Jun;55(6):505-21. | ||||||||||
| Title: | Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology. | ||||||||||
| Author: | Jesinghaus, Moritz|Pfarr, Nicole|Endris, Volker|Kloor, Matthias|Volckmar, Anna-Lena|Brandt, Regine|Herpel, Esther|Muckenhuber, Alexander|Lasitschka, Felix|Schirmacher, Peter|Penzel, Roland|Weichert, Wilko|Stenzinger, Albrecht | ||||||||||
| PMID: | 26917275 | ||||||||||
| 30. | |||||||||||
| Journal: | Br J Cancer. 2017 Jun 27;117(1):136-143. | ||||||||||
| Title: | Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia. | ||||||||||
| Author: | Chakrabarty, Sanjiban|Varghese, Vinay Koshy|Sahu, Pranoy|Jayaram, Pradyumna|Shivakumar, Bhadravathi M|Pai, Cannanore Ganesh|Satyamoorthy, Kapaettu | ||||||||||
| PMID: | 28524162 | ||||||||||
| 31. | |||||||||||
| Journal: | J Cancer. 2018 Sep 8;9(19):3626-3633. | ||||||||||
| Title: | Downregulation of Activin A Receptor Type 2A Is Associated with Metastatic Potential and Poor Prognosis of Colon Cancer. | ||||||||||
| Author: | Zhuo, Changhua|Hu, Dan|Li, Jing|Yu, Hui|Lin, Xiandong|Chen, Ying|Zhuang, Yong|Li, Qingguo|Zheng, Xiongwei|Yang, Chunkang | ||||||||||
| PMID: | 30310521 | ||||||||||