Primary Site >> Colorectal Cancer

Gene >> ACVR2A

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Ref: Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability.
PMID: 11507051
Ref: Overexpression of activin A in stage IV colorectal cancer.
PMID: 11511564
Ref: Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors.
PMID: 14691305
Ref: Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers.
PMID: 14988818
Ref: Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.
PMID: 15520171
Ref: Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers.
PMID: 16380996
Ref: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer.
PMID: 16421660
Ref: Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin.
PMID: 17258738
Ref: Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
PMID: 17478078
Ref: Intraovarian activins are required for female fertility.
PMID: 17609433
Ref: Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.
PMID: 19293232
Ref: Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.
PMID: 19503063
Ref: Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms.
PMID: 20011542
Ref: SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology.
PMID: 19820113
Ref: Coding microsatellite instability analysis in microsatellite unstable small intestinal adenocarcinomas identifies MARCKS as a common target of inactivation.
PMID: 19852062
Ref: Candidate driver genes in microsatellite-unstable colorectal cancer.
PMID: 21544814
Ref: Effects of activin and TGFbeta on p21 in colon cancer.
PMID: 22761777
Ref: Comprehensive molecular characterization of human colon and rectal cancer.
PMID: 22810696
Ref: Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.
PMID: 23700467
Ref: Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
PMID: 24755471
Ref: De Novo proteome analysis of genetically modified tumor cells by a metabolic labeling/azide-alkyne cycloaddition approach.
PMID: 25225355
Ref: Microsatellite instability: an update.
PMID: 25701956
Ref: Transforming Growth Factor beta Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.
PMID: 25736321
Ref: Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.
PMID: 25786087
Ref: Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.
PMID: 26247575
Ref: Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinoma.
PMID: 26336987
Ref: Activin and TGFbeta use diverging mitogenic signaling in advanced colon cancer.
PMID: 26497569
Ref: Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma.
PMID: 26806338
Ref: Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
PMID: 26917275
Ref: Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
PMID: 28524162
Ref: Downregulation of Activin A Receptor Type 2A Is Associated with Metastatic Potential and Poor Prognosis of Colon Cancer.
PMID: 30310521