Primary Site >> Pancreatic Cancer

Gene >> ABL1

Journal: Mol Cancer. 2003 Sep 17;2:32.
Title: Effects of STI571 (gleevec) on pancreatic cancer cell growth.
Author: Li, Junsheng|Kleeff, Jorg|Guo, Junchao|Fischer, Lars|Giese, Nathalia|Buchler, Markus W|Friess, Helmut
PMID: 14521721
Journal: Am J Pathol. 2006 Mar;168(3):962-72.
Title: Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.
Author: Trevino, Jose G|Summy, Justin M|Lesslie, Donald P|Parikh, Nila U|Hong, David S|Lee, Francis Y|Donato, Nicholas J|Abbruzzese, James L|Baker, Cheryl H|Gallick, Gary E
PMID: 16507911
Journal: J Med Chem. 2006 Nov 2;49(22):6465-88.
Title: N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
Author: Hennequin, Laurent F|Allen, Jack|Breed, Jason|Curwen, Jon|Fennell, Michael|Green, Tim P|Lambert-van der Brempt, Christine|Morgentin, Remy|Norman, Richard A|Olivier, Annie|Otterbein, Ludovic|Ple, Patrick A|Warin, Nicolas|Costello, Gerard
PMID: 17064066
Journal: Br J Cancer. 2008 Oct 7;99(7):1074-82.
Title: Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.
Author: Chang, Q|Jorgensen, C|Pawson, T|Hedley, D W
PMID: 18797457
Journal: Cell Adh Migr. 2009 Apr-Jun;3(2):167-70. Epub 2009 Apr 5.
Title: ArgBP2 and the SoHo family of adapter proteins in oncogenic diseases.
Author: Roignot, Julie|Soubeyran, Philippe
PMID: 19262174
Journal: Mol Cancer Ther. 2009 Jun;8(6):1484-93.
Title: Efficacy and pharmacodynamic effects of bosutinib (SKI-606), a Src/Abl inhibitor, in freshly generated human pancreas cancer xenografts.
Author: Messersmith, Wells A|Rajeshkumar, N V|Tan, Aik Choon|Wang, Xiao Fei|Diesl, Veronica|Choe, Sung E|Follettie, Max|Coughlin, Christina|Boschelli, Frank|Garcia-Garcia, Elena|Lopez-Rios, Fernando|Jimeno, Antonio|Hidalgo, Manuel
PMID: 19509264
Journal: Cancer Lett. 2010 Feb 1;288(1):116-23.
Title: CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration.
Author: Roignot, J|Taieb, D|Suliman, M|Dusetti, N J|Iovanna, J L|Soubeyran, P
PMID: 19631450
Journal: J Biol Chem. 2010 Jul 23;285(30):23075-85.
Title: Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
Author: Lazer, Galit|Pe'er, Liron|Farago, Marganit|Machida, Kazuya|Mayer, Bruce J|Katzav, Shulamit
PMID: 20457609
Journal: Cancer Lett. 2011 Jul 28;306(2):180-9.
Title: RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation.
Author: Walsh, Naomi|Larkin, AnneMarie|Swan, Niall|Conlon, Kevin|Dowling, Paul|McDermott, Ray|Clynes, Martin
PMID: 21470770
Journal: J Pharmacol Exp Ther. 2012 Dec;343(3):617-27.
Title: Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptor/platelet-derived growth factor receptor, and Src kinase families.
Author: Glaser, Keith B|Li, Junling|Marcotte, Patrick A|Magoc, Terrance J|Guo, Jun|Reuter, David R|Tapang, Paul|Wei, Ru-Qi|Pease, Lori J|Bui, Mai H|Chen, Zehan|Frey, Robin R|Johnson, Eric F|Osterling, Donald J|Olson, Amanda M|Bouska, Jennifer J|Luo, Yanping|Curti
PMID: 22935731
Journal: Gastroenterology. 2014 Jan;146(1):245-56.
Title: DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer.
Author: Bailey, Jennifer M|Alsina, Janivette|Rasheed, Zeshaan A|McAllister, Florencia M|Fu, Ya-Yuan|Plentz, Ruben|Zhang, Hao|Pasricha, Pankaj J|Bardeesy, Nabeel|Matsui, William|Maitra, Anirban|Leach, Steven D
PMID: 24096005
Journal: PLoS One. 2014 Jan 27;9(1):e87130.
Title: Oligomerization and phosphorylation dependent regulation of ArgBP2 adaptive capabilities and associated functions.
Author: Roignot, Julie|Bonacci, Thomas|Ghigo, Eric|Iovanna, Juan L|Soubeyran, Philippe
PMID: 24475245
Journal: J Clin Bioinforma. 2014 Feb 18;4(1):3.
Title: Development of detection method for novel fusion gene using GeneChip exon array.
Author: Wada, Yusaku|Matsuura, Masaaki|Sugawara, Minoru|Ushijima, Masaru|Miyata, Satoshi|Nagasaki, Koichi|Noda, Tetsuo|Miki, Yoshio
PMID: 24533689
Journal: Cell Cycle. 2014;13(14):2172-91.
Title: Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints.
Author: Beeharry, Neil|Banina, Eugenia|Hittle, James|Skobeleva, Natalia|Khazak, Vladimir|Deacon, Sean|Andrake, Mark|Egleston, Brian L|Peterson, Jeffrey R|Astsaturov, Igor|Yen, Timothy J
PMID: 24955955
Journal: Am J Pathol. 2014 Oct;184(10):2791-802.
Title: Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth.
Author: Bi, Yan|Li, Jiachu|Ji, Baoan|Kang, Ningling|Yang, Liu|Simonetto, Douglas A|Kwon, Jung H|Kamath, Marielle|Cao, Sheng|Shah, Vijay
PMID: 25111230