Primary Site >> Colorectal Cancer

Gene >> ABL1

Journal: Int J Cancer. 1988 Feb 15;41(2):287-96.
Title: Biological characterization and oncogene expression in human colorectal carcinoma cell lines.
Author: Trainer, D L|Kline, T|McCabe, F L|Faucette, L F|Feild, J|Chaikin, M|Anzano, M|Rieman, D|Hoffstein, S|Li, D J
PMID: 3338874
Journal: Am J Med Sci. 1991 Apr;301(4):238-45.
Title: Enhanced expression of oncogene-encoded mRNA in a rat model of colon cancer.
Author: Alexander, R J|Buxbaum, J N|Raicht, R F
PMID: 2012108
Journal: Ann N Y Acad Sci. 1993 Aug 12;690:101-12.
Title: T-cell immunity to oncogenic proteins including mutated ras and chimeric bcr-abl.
Author: Cheever, M A|Chen, W|Disis, M L|Takahashi, M|Peace, D J
PMID: 8103658
Journal: Dig Dis Sci. 1996 Apr;41(4):660-9.
Title: Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease.
Author: Alexander, R J|Panja, A|Kaplan-Liss, E|Mayer, L|Raicht, R F
PMID: 8674385
Journal: J Biol Chem. 1999 Feb 19;274(8):4890-9.
Title: Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import.
Author: Yu, L G|Fernig, D G|White, M R|Spiller, D G|Appleton, P|Evans, R C|Grierson, I|Smith, J A|Davies, H|Gerasimenko, O V|Petersen, O H|Milton, J D|Rhodes, J M
PMID: 9988731
Journal: Gut. 1999 May;44(5):709-14.
Title: Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells.
Author: Jordinson, M|El-Hariry, I|Calnan, D|Calam, J|Pignatelli, M
PMID: 10205210
Journal: Int J Cancer. 1999 Nov 26;83(5):579-84.
Title: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
Author: Chen, W S|Kung, H J|Yang, W K|Lin, W c
PMID: 10521789
Journal: Biochem J. 2002 Jun 1;364(Pt 2):441-7.
Title: Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
Author: Catani, M Valeria|Costanzo, Antonio|Savini, Isabella|Levrero, Massimo|de Laurenzi, Vincenzo|Wang, Jean Y J|Melino, Gerry|Avigliano, Luciana
PMID: 12023887
Journal: Cancer Res. 2002 Sep 1;62(17):4879-83.
Title: The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy.
Author: Attoub, Samir|Rivat, Christine|Rodrigues, Sylvie|Van Bocxlaer, Saskia|Bedin, Monique|Bruyneel, Erik|Louvet, Christophe|Kornprobst, Michel|Andre, Thierry|Mareel, Marc|Mester, Jan|Gespach, Christian
PMID: 12208734
Journal: FEBS Lett. 2003 Apr 10;540(1-3):195-200.
Title: Induction of colonic epithelial cell apoptosis by p47-dependent oxidants.
Author: Gu, Ying|Souza, Rhonda F|Wu, Ru Feng|Xu, You Cheng|Terada, Lance S
PMID: 12681507
Journal: Cancer Biol Ther. 2004 Apr;3(4):385-92. Epub 2004 Apr 18.
Title: Inhibition of cell survival and invasive potential of colorectal carcinoma cells by the tyrosine kinase inhibitor STI571.
Author: Bellone, Graziella|Ferrero, Dario|Carbone, Anna|De Quadros, Marlene R|Gramigni, Claudia|Prati, Adriana|Davidson, William|Mioli, Pierroberto|Dughera, Luca|Emanuelli, Giorgio|Rodeck, Ulrich
PMID: 14726674
Journal: Biochim Biophys Acta. 2004 Mar 11;1697(1-2):17-27.
Title: Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis.
Author: Manley, Paul William|Bold, Guido|Bruggen, Josef|Fendrich, Gabrielle|Furet, Pascal|Mestan, Jurgen|Schnell, Christian|Stolz, Barbara|Meyer, Thomas|Meyhack, Bernd|Stark, Wilhelm|Strauss, Andre|Wood, Jeanette
PMID: 15023347
Journal: Endocr Relat Cancer. 2004 Dec;11(4):861-9.
Title: Expression of tyrosine kinases in human malignancies as potential targets for kinase-specific inhibitors.
Author: Singer, Christian F|Hudelist, Gernot|Lamm, Wolfgang|Mueller, Ruth|Czerwenka, Klaus|Kubista, Ernst
PMID: 15613459
Journal: J Exp Clin Cancer Res. 2005 Dec;24(4):505-14.
Title: Genetic models of human cancer as a multistep process. Paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukaemia.
Author: Karakosta, A|Golias, Ch|Charalabopoulos, A|Peschos, D|Batistatou, A|Charalabopoulos, K
PMID: 16471312
Journal: EMBO Rep. 2005 Nov;6(11):1095-100. Epub 2005 Oct 7.
Title: Bcr is a negative regulator of the Wnt signalling pathway.
Author: Ress, Angelika|Moelling, Karin
PMID: 16211085
Journal: Blood Cells Mol Dis. 2005 Mar-Apr;34(2):181-5.
Title: Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Author: Holdhoff, Matthias|Kreuzer, Karl-Anton|Appelt, Christine|Scholz, Regina|Na, Il-Kang|Hildebrandt, Bert|Riess, Hanno|Jordan, Andreas|Schmidt, Christian A|Van Etten, Richard A|Dorken, Bernd|le Coutre, Philipp
PMID: 15727903
Journal: Oncol Rep. 2006 Feb;15(2):353-9.
Title: Active (p)CrkL is overexpressed in human malignancies: potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition.
Author: Singer, Christian F|Hudelist, Gernot|Lamm, Wolfgang|Mueller, Ruth|Handl, Claudia|Kubista, Ernst|Czerwenka, Klaus
PMID: 16391854
Journal: Mol Cancer Ther. 2006 Feb;5(2):400-10.
Title: c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells.
Author: Thottassery, Jaideep V|Westbrook, Louise|Someya, Hitoshi|Parker, William B
PMID: 16505115
Journal: Mutat Res. 2007 Feb 3;615(1-2):1-11. Epub 2007 Jan 2.
Title: aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL.
Author: Bartos, Jeremy D|Gaile, Daniel P|McQuaid, Devin E|Conroy, Jeffrey M|Darbary, Huferesh|Nowak, Norma J|Block, Annemarie|Petrelli, Nicholas J|Mittelman, Arnold|Stoler, Daniel L|Anderson, Garth R
PMID: 17196995
Journal: Pharmacol Res. 2007 Sep;56(3):248-53.
Title: Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro.
Author: Rossi, Lorena|Bonmassar, Enzo|Faraoni, Isabella
PMID: 17702597
Journal: Curr Med Chem. 2007;14(29):3122-38.
Title: Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Author: Stravopodis, Dimitrios J|Margaritis, Lukas H|Voutsinas, Gerassimos E
PMID: 18220746
Journal: Neurosignals. 2008;16(2-3):235-45.
Title: Tyrosine phosphorylation of netrin receptors in netrin-1 signaling.
Author: Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng
PMID: 18253061
Journal: Pharmacogenomics. 2008 Apr;9(4):463-7.
Title: DxS Ltd.
Author: Cross, Joanne
PMID: 18384259
Journal: J Biol Chem. 2008 Aug 1;283(31):21382-93.
Title: Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.
Author: Wagner, Mark W|Li, Long Shan|Morales, Julio C|Galindo, Cristi L|Garner, Harold R|Bornmann, William G|Boothman, David A
PMID: 18480061
Journal: DNA Repair (Amst). 2009 Mar 1;8(3):390-9.
Title: HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
Author: Ferrandiz, Nuria|Martin-Perez, Jorge|Blanco, Rosa|Donertas, Derya|Weber, Axel|Eilers, Martin|Dotto, Paolo|Delgado, M Dolores|Leon, Javier
PMID: 19150257
Journal: J Psychosom Res. 2009 Mar;66(3):259-66.
Title: The level of oxidative stress and the expression of genes involved in DNA-damage signaling pathways in depressive patients with colorectal carcinoma.
Author: Wei, Yong-chang|Zhou, Fu-ling|He, Da-lin|Bai, Ji-rong|Hui, Ling-yun|Wang, Xin-yang|Nan, Ke-jun
PMID: 19232240
Journal: Biochemistry. 2009 Jun 9;48(22):4780-8.
Title: Bimolecular fluorescence complementation demonstrates that the c-Fes protein-tyrosine kinase forms constitutive oligomers in living cells.
Author: Shaffer, Jonathan M|Hellwig, Sabine|Smithgall, Thomas E
PMID: 19382747
Journal: Exp Cell Res. 2009 Nov 1;315(18):3163-75.
Title: MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.
Author: Sun, Guoming|Jin, Shunqian|Baskaran, R
PMID: 19766113
Journal: Cell. 2009 Nov 13;139(4):679-92.
Title: Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.
Author: Genander, Maria|Halford, Michael M|Xu, Nan-Jie|Eriksson, Malin|Yu, Zuoren|Qiu, Zhaozhu|Martling, Anna|Greicius, Gedas|Thakar, Sonal|Catchpole, Timothy|Chumley, Michael J|Zdunek, Sofia|Wang, Chenguang|Holm, Torbjorn|Goff, Stephen P|Pettersson, Sven|Pestell
PMID: 19914164
Journal: PLoS One. 2010 Nov 30;5(11):e14143.
Title: Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers.
Author: Kruewel, Thomas|Schenone, Silvia|Radi, Marco|Maga, Giovanni|Rohrbeck, Astrid|Botta, Maurizio|Borlak, Juergen
PMID: 21152443
Journal: BMC Cancer. 2010 Mar 16;10:101.
Title: A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
Author: Fumagalli, Debora|Gavin, Patrick G|Taniyama, Yusuke|Kim, Seung-Il|Choi, Hyun-Joo|Paik, Soonmyung|Pogue-Geile, Katherine L
PMID: 20233444
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1054-67.
Title: Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membrane.
Author: Funakoshi, Shinsuke|Kong, Jianping|Crissey, Mary Ann|Dang, Long|Dang, Duyen|Lynch, John P
PMID: 20671195
Journal: Curr Drug Targets. 2011 Apr;12(4):563-78.
Title: Dasatinib: an anti-tumour agent via Src inhibition.
Author: Gnoni, Antonio|Marech, Ilaria|Silvestris, Nicola|Vacca, Angelo|Lorusso, Vito
PMID: 21226671
Journal: Clin Cancer Res. 2011 Sep 1;17(17):5546-52.
Title: Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
Author: Montero, Juan Carlos|Seoane, Samuel|Ocana, Alberto|Pandiella, Atanasio
PMID: 21670084
Journal: Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17135-40.
Title: Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling.
Author: Scholer-Dahirel, Alix|Schlabach, Michael R|Loo, Alice|Bagdasarian, Linda|Meyer, Ronald|Guo, Ribo|Woolfenden, Steve|Yu, Kristine K|Markovits, Judit|Killary, Karen|Sonkin, Dmitry|Yao, Yung-Mae|Warmuth, Markus|Sellers, William R|Schlegel, Robert|Stegmeier, F
PMID: 21949247
Journal: J Biomed Sci. 2012 Mar 30;19:35.
Title: STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death.
Author: Huang, Duen-Yi|Chao, Yee|Tai, Ming-Hui|Yu, Yang-Hao|Lin, Wan-Wan
PMID: 22462553
Journal: Expert Rev Mol Diagn. 2012 Jul;12(6):593-602.
Title: Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.
Author: Ong, Frank S|Das, Kingshuk|Wang, Jay|Vakil, Hana|Kuo, Jane Z|Blackwell, Wendell-Lamar B|Lim, Stephen W|Goodarzi, Mark O|Bernstein, Kenneth E|Rotter, Jerome I|Grody, Wayne W
PMID: 22845480
Journal: PLoS Genet. 2013 Apr;9(4):e1003464.
Title: Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
Author: Giacomini, Craig P|Sun, Steven|Varma, Sushama|Shain, A Hunter|Giacomini, Marilyn M|Balagtas, Jay|Sweeney, Robert T|Lai, Everett|Del Vecchio, Catherine A|Forster, Andrew D|Clarke, Nicole|Montgomery, Kelli D|Zhu, Shirley|Wong, Albert J|van de Rijn, Matt|Wes
PMID: 23637631
Journal: Mol Biol Rep. 2013 Jun;40(6):4109-14.
Title: The prevalence and prognostic significance of KRAS mutation in bladder cancer, chronic myeloid leukemia and colorectal cancer.
Author: Ouerhani, Slah|Bougatef, Karim|Soltani, Ismail|Elgaaied, Amel Ben Ammar|Abbes, Salem|Menif, Samia
PMID: 23640097
Journal: PLoS One. 2013 May 16;8(5):e63580.
Title: Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines.
Author: Ng, Yu Pong|Chen, Yuewen|Hu, Yueqing|Ip, Fanny C F|Ip, Nancy Y
PMID: 23696836
Journal: Mol Cell Endocrinol. 2013 Sep 5;377(1-2):1-6.
Title: Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase.
Author: Mologni, Luca|Redaelli, Sara|Morandi, Andrea|Plaza-Menacho, Ivan|Gambacorti-Passerini, Carlo
PMID: 23811235
Journal: Caspian J Intern Med. 2013 Summer;4(3):739-42.
Title: Chronic myeloid leukemia following colon cancer treatment: A case report and literature review.
Author: Vakili-Sadeghi, Mohsen|Omranpour, Mohammadhasan
PMID: 24009972
Journal: J Cancer Res Clin Oncol. 2013 Dec;139(12):2133-40.
Title: Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer.
Author: Nygren, Peter|Fryknas, Marten|Agerup, Bengt|Larsson, Rolf
PMID: 24135855
Journal: Mol Cancer. 2014 Jun 9;13:145.
Title: Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.
Author: Steinestel, Konrad|Bruderlein, Silke|Lennerz, Jochen K|Steinestel, Julie|Kraft, Klaus|Propper, Christian|Meineke, Viktor|Moller, Peter
PMID: 24913355
Journal: Bull Acad Natl Med. 2014 Jan;198(1):101-17.
Title: [Genome sequencing and personalized medicine: perspectives and limitations].
Author: Le Gall, Jean-Yves|Debre, Patrice
PMID: 26259290
Journal: Cancer Discov. 2015 Feb;5(2):198-211.
Title: Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO.
Author: Sonoshita, Masahiro|Itatani, Yoshiro|Kakizaki, Fumihiko|Sakimura, Kenji|Terashima, Toshio|Katsuyama, Yu|Sakai, Yoshiharu|Taketo, M Mark
PMID: 25432929
Journal: Semin Oncol. 2015 Dec;42(6):896-908.
Title: Overcoming Resistance to Targeted Therapies in Cancer.
Author: Redmond, Keara L|Papafili, Anastasia|Lawler, Mark|Van Schaeybroeck, Sandra
PMID: 26615134
Journal: J Gastrointest Cancer. 2015 Dec;46(4):380-9.
Title: Optimizing and predicting the in vivo activity of AT9283 as a monotherapy and in combination with paclitaxel.
Author: Moawad, Emad Y
PMID: 26346504
Journal: Mol Cell Biochem. 2016 Mar;414(1-2):13-22.
Title: GADD45alpha modulates curcumin sensitivity through c-Abl- and JNK-dependent signaling pathways in a mismatch repair-dependent manner.
Author: Naick, Hemanth|Jin, Shunqian|Baskaran, R
PMID: 26833194
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author: Pfarr, Nicole|Penzel, Roland|Klauschen, Frederick|Heim, Daniel|Brandt, Regine|Kazdal, Daniel|Jesinghaus, Moritz|Herpel, Esther|Schirmacher, Peter|Warth, Arne|Weichert, Wilko|Endris, Volker|Stenzinger, Albrecht
PMID: 27218826
Journal: ChemMedChem. 2016 Aug 5;11(15):1587-95.
Title: Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity.
Author: El-Damasy, Ashraf Kareem|Cho, Nam-Chul|Nam, Ghilsoo|Pae, Ae Nim|Keum, Gyochang
PMID: 27405013
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: Biomed Pharmacother. 2017 Jan;85:389-398.
Title: In-silico and in-vitro anti-cancer potential of a curcumin analogue (1E, 6E)-1, 7-di (1H-indol-3-yl) hepta-1, 6-diene-3, 5-dione.
Author: Sufi, Shamim Akhtar|Adigopula, Lakshmi Narayana|Syed, Safiulla Basha|Mukherjee, Victor|Coumar, Mohane S|Rao, H Surya Prakash|Rajagopalan, Rukkumani
PMID: 27889234
Journal: Bioorg Med Chem. 2017 Oct 15;25(20):5423-5432.
Title: Biological evaluation of 2-pyrazolinyl-1-carbothioamide derivatives against HCT116 human colorectal cancer cell lines and elucidation on QSAR and molecular binding modes.
Author: Kim, Beom Soo|Shin, Soon Young|Ahn, Seunghyun|Koh, Dongsoo|Lee, Young Han|Lim, Yoongho
PMID: 28811071
Journal: PLoS One. 2017 Nov 1;12(11):e0187173.
Title: Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Author: Scott, Aaron J|Song, Eun-Kee|Bagby, Stacey|Purkey, Alicia|McCarter, Martin|Gajdos, Csaba|Quackenbush, Kevin S|Cross, Benjamin|Pitts, Todd M|Tan, Aik Choon|Eckhardt, S Gail|Fenton, Hubert|Arcaroli, John|Messersmith, Wells A
PMID: 29091939
Journal: Oncogene. 2018 Feb 1;37(5):663-672.
Title: 'MCC' protein interacts with E-cadherin and beta-catenin strengthening cell-cell adhesion of HCT116 colon cancer cells.
Author: Benthani, F A|Herrmann, D|Tran, P N|Pangon, L|Lucas, M C|Allam, A H|Currey, N|Al-Sohaily, S|Giry-Laterriere, M|Warusavitarne, J|Timpson, P|Kohonen-Corish, M R J
PMID: 29035389
Journal: Food Chem. 2018 Mar 1;242:378-388.
Title: Comparison of the effect of chemical composition of anthocyanin-rich plant extracts on colon cancer cell proliferation and their potential mechanism of action using in vitro, in silico, and biochemical assays.
Author: Mazewski, Candice|Liang, Katie|Gonzalez de Mejia, Elvira
PMID: 29037704
Journal: Onco Targets Ther. 2018 Jan 31;11:609-618.
Title: Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis.
Author: Peng, Qiliang|Lin, Kaisu|Chang, Tao|Zou, Li|Xing, Pengfei|Shen, Yuntian|Zhu, Yaqun
PMID: 29430186
Journal: Eur J Med Chem. 2018 May 25;152:31-52.
Title: Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition.
Author: Malki, Waleed H|Gouda, Ahmed M|Ali, Hamdy E A|Al-Rousan, Rabaa|Samaha, Doaa|Abdalla, Ashraf N|Bustamante, Juan|Abd Elmageed, Zakaria Y|Ali, Hamed I
PMID: 29684708