Primary Site >> Colorectal Cancer

Gene >> ABCC4

Journal: Biochem Pharmacol. 2001 Mar 1;61(5):555-63.
Title: Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status.
Author: Lin-Lee, Y C|Tatebe, S|Savaraj, N|Ishikawa, T|Tien Kuo, M
PMID: 11239498
Journal: Curr Cancer Drug Targets. 2008 Aug;8(5):414-20.
Title: Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy.
Author: Gradilone, A|Pulcinelli, F M|Lotti, L V|Trifiro, E|Martino, S|Gandini, O|Gianni, W|Frati, L|Agliano, A M|Gazzaniga, P
PMID: 18690847
Journal: Cancer Prev Res (Phila). 2008 Jul;1(2):93-9.
Title: Regulation of prostaglandin transporters in colorectal neoplasia.
Author: Holla, Vijaykumar R|Backlund, Michael G|Yang, Peying|Newman, Robert A|DuBois, Raymond N
PMID: 19138942
Journal: Mol Cancer Ther. 2009 Mar;8(3):655-64.
Title: Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins.
Author: Lemos, Clara|Kathmann, Ietje|Giovannetti, Elisa|Belien, Jeroen A M|Scheffer, George L|Calhau, Conceicao|Jansen, Gerrit|Peters, Godefridus J
PMID: 19240161
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Aug;14(8):627-30.
Title: [Preliminary study on relationship between multi-drug resistance-associated protein 4 and radiosensitivity of rectal cancer].
Author: Chai, Rui|Yu, Zhi-qi|Fu, Chuan-gang|Wang, Hao|Zhang, Wei|Liu, Lian-jie|Zhang, Chang
PMID: 21866459
Journal: Clin Cancer Res. 2011 Nov 15;17(22):7139-47.
Title: Genetic variation in inflammatory pathways is related to colorectal cancer survival.
Author: Coghill, Anna E|Newcomb, Polly A|Poole, Elizabeth M|Hutter, Carolyn M|Makar, Karen W|Duggan, Dave|Potter, John D|Ulrich, Cornelia M
PMID: 21976545
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Jan;15(1):67-71.
Title: [Down regulation of multidrug resistance-associated protein 4 expression by RNA interference enhances radiosensitivity of colorectal carcinoma cell lines in vitro].
Author: Yu, Zhi-qi|Zhang, Chang|Cai, Rui|Lao, Xin-yuan|Wang, Hao|Gao, Xian-hua|Han, Yi-fang|Zhang, Xiao-qing|Cao, Guang-wen|Fu, Chuan-gang
PMID: 22287356
Journal: Phytomedicine. 2012 May 15;19(7):625-30.
Title: Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.
Author: Lai, Kuang-Chi|Kuo, Chao-Lin|Ho, Heng-Chien|Yang, Jai-Sing|Ma, Chia-Yu|Lu, Hsu-Feng|Huang, Hui-Ying|Chueh, Fu-Shin|Yu, Chien-Chih|Chung, Jing-Gung
PMID: 22397993
Journal: PLoS One. 2014 Jan 15;9(1):e85446.
Title: Prognostic significance and molecular mechanism of ATP-binding cassette subfamily C member 4 in resistance to neoadjuvant radiotherapy of locally advanced rectal carcinoma.
Author: Yu, Zhiqi|Zhang, Chang|Chai, Rui|Du, Yan|Gao, Xianhua|Xing, Junjie|Yu, Enda|Zhang, Wei|Zhang, Xiaoqing|Cao, Guangwen|Fu, Chuangang
PMID: 24454870
Journal: PLoS One. 2014 Apr 2;9(4):e92000.
Title: Genetic variability in key genes in prostaglandin E2 pathway (COX-2, HPGD, ABCC4 and SLCO2A1) and their involvement in colorectal cancer development.
Author: Pereira, Carina|Queiros, Sara|Galaghar, Ana|Sousa, Hugo|Pimentel-Nunes, Pedro|Brandao, Catarina|Moreira-Dias, Luis|Medeiros, Rui|Dinis-Ribeiro, Mario
PMID: 24694755
Journal: Biochem Pharmacol. 2015 Feb 1;93(3):380-8.
Title: Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen.
Author: Cheung, Leanna|Yu, Denise M T|Neiron, Zillan|Failes, Tim W|Arndt, Greg M|Fletcher, Jamie I
PMID: 25462817
Journal: J Biol Chem. 2015 May 1;290(18):11246-57.
Title: Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
Author: Moon, Changsuk|Zhang, Weiqiang|Ren, Aixia|Arora, Kavisha|Sinha, Chandrima|Yarlagadda, Sunitha|Woodrooffe, Koryse|Schuetz, John D|Valasani, Koteswara Rao|de Jonge, Hugo R|Shanmukhappa, Shiva Kumar|Shata, Mohamed Tarek M|Buddington, Randal K|Parthasarathi,
PMID: 25762723
Journal: Onco Targets Ther. 2016 May 6;9:2735-42.
Title: miR-17-92a-1 cluster host gene (MIR17HG) evaluation and response to neoadjuvant chemoradiotherapy in rectal cancer.
Author: Molinari, Chiara|Salvi, Samanta|Foca, Flavia|Teodorani, Nazario|Saragoni, Luca|Puccetti, Maurizio|Passardi, Alessandro|Tamberi, Stefano|Avanzolini, Andrea|Lucci, Enrico|Calistri, Daniele
PMID: 27226732
Journal: Anticancer Res. 2017 Jan;37(1):281-291.
Title: Prognostic and Therapeutic Potential Implications of Genetic Variability in Prostaglandin E2 Pathway Genes in Rectal Cancer.
Author: Santos, Marisa D|Silva, Cristina|Rocha, Anabela|Nogueira, Carlos|Castro-Pocas, Fernando|Araujo, Antonio|Matos, Eduarda|Pereira, Carina|Medeiros, Rui|Lopes, Carlos
PMID: 28011504
Journal: Sci Rep. 2017 Aug 1;7(1):7059.
Title: A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients.
Author: Chen, Qi|Meng, Fanyi|Wang, Lei|Mao, Yong|Zhou, Huan|Hua, Dong|Zhang, Hongjian|Wang, Weipeng
PMID: 28765596
Journal: Pharmacol Res. 2018 Sep 11;136:133-139.
Title: Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
Author: Salvador-Martin, Sara|Garcia-Gonzalez, Xandra|Garcia, Maria I|Blanco, Carolina|Garcia-Alfonso, Pilar|Robles, Luis|Gravalos, Cristina|Pachon, Vanessa|Longo, Federico|Martinez, Virginia|Sanjurjo-Saez, Maria|Lopez-Fernandez, Luis A
PMID: 30213564