Primary Site >> Colorectal Cancer

Gene >> ABCC4

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Ref: Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status.
PMID: 11239498
Ref: Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy.
PMID: 18690847
Ref: Regulation of prostaglandin transporters in colorectal neoplasia.
PMID: 19138942
Ref: Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins.
PMID: 19240161
Ref: [Preliminary study on relationship between multi-drug resistance-associated protein 4 and radiosensitivity of rectal cancer].
PMID: 21866459
Ref: Genetic variation in inflammatory pathways is related to colorectal cancer survival.
PMID: 21976545
Ref: [Down regulation of multidrug resistance-associated protein 4 expression by RNA interference enhances radiosensitivity of colorectal carcinoma cell lines in vitro].
PMID: 22287356
Ref: Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.
PMID: 22397993
Ref: Prognostic significance and molecular mechanism of ATP-binding cassette subfamily C member 4 in resistance to neoadjuvant radiotherapy of locally advanced rectal carcinoma.
PMID: 24454870
Ref: Genetic variability in key genes in prostaglandin E2 pathway (COX-2, HPGD, ABCC4 and SLCO2A1) and their involvement in colorectal cancer development.
PMID: 24694755
Ref: Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen.
PMID: 25462817
Ref: Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
PMID: 25762723
Ref: miR-17-92a-1 cluster host gene (MIR17HG) evaluation and response to neoadjuvant chemoradiotherapy in rectal cancer.
PMID: 27226732
Ref: Prognostic and Therapeutic Potential Implications of Genetic Variability in Prostaglandin E2 Pathway Genes in Rectal Cancer.
PMID: 28011504
Ref: A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients.
PMID: 28765596
Ref: Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
PMID: 30213564