Primary Site >> Liver Cancer

Gene >> ABCC2

Journal: Eur J Gastroenterol Hepatol. 2000 Nov;12(11):1253-7.
Title: Multiple black hepatocellular adenomas in a male patient.
Author: Bernard, P H|Blanc, J F|Paulusma, C|Le Bail, B|Carles, J|Balabaud, C|Bioulac-Sage, P
PMID: 11111785
Journal: J Cell Physiol. 2000 Apr;183(1):108-16.
Title: Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake.
Author: Shen, D W|Goldenberg, S|Pastan, I|Gottesman, M M
PMID: 10699972
Journal: Int J Cancer. 2001 Nov;94(4):492-9.
Title: Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.
Author: Nies, A T|Konig, J|Pfannschmidt, M|Klar, E|Hofmann, W J|Keppler, D
PMID: 11745434
Journal: Mol Pharmacol. 2003 Mar;63(3):742-50.
Title: Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.
Author: Briz, Oscar|Macias, Rocio I R|Vallejo, Marta|Silva, Augusto|Serrano, Maria Angeles|Marin, Jose J G
PMID: 12606785
Journal: Liver Int. 2005 Apr;25(2):367-79.
Title: Hepatobiliary transporter expression in human hepatocellular carcinoma.
Author: Zollner, Gernot|Wagner, Martin|Fickert, Peter|Silbert, Dagmar|Fuchsbichler, Andrea|Zatloukal, Kurt|Denk, Helmut|Trauner, Michael
PMID: 15780063
Journal: Cancer Gene Ther. 2007 Nov;14(11):875-84.
Title: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs.
Author: Folmer, Y|Schneider, M|Blum, H E|Hafkemeyer, P
PMID: 17704753
Journal: Int J Oncol. 2007 Dec;31(6):1465-72.
Title: The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins.
Author: Wakamatsu, Takahiro|Nakahashi, Yoshitsugu|Hachimine, Daisaku|Seki, Toshihito|Okazaki, Kazuichi
PMID: 17982673
Journal: Digestion. 2009;80(1):36-9.
Title: Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer.
Author: Hoblinger, A|Grunhage, F|Sauerbruch, T|Lammert, F
PMID: 19451719
Journal: Oncol Rep. 2009 Jul;22(1):73-80.
Title: The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
Author: Chen, Xi|Zhang, Mu|Liu, Lian-Xin
PMID: 19513507
Journal: Mol Pharm. 2009 Nov-Dec;6(6):1678-88.
Title: Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Author: Adachi, Tatsuhiko|Nakagawa, Hiroshi|Hagiya, Yuichiro|Yasuoka, Tatsuya|Ishikawa, Toshihisa
PMID: 19588995
Journal: Chin J Cancer. 2010 Feb;29(2):167-71.
Title: Establishment of a cisplatin-induced multidrug resistance cell line SK-Hep1/DDP.
Author: Zhou, Yuan|Ling, Xian-Long
PMID: 20109345
Journal: Anticancer Res. 2011 Nov;31(11):3883-90.
Title: Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Author: Hoffmann, Katrin|Shibo, Lin|Xiao, Zhi|Longerich, Thomas|Buchler, Markus W|Schemmer, Peter
PMID: 22110214
Journal: Hepatology. 2012 Mar;55(3):821-32.
Title: Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.
Author: Borel, Florie|Han, Ruiqi|Visser, Allerdien|Petry, Harald|van Deventer, Sander J H|Jansen, Peter L M|Konstantinova, Pavlina
PMID: 21932399
Journal: Hepatology. 2012 Jun;55(6):1820-9.
Title: Amplified in breast cancer 1 enhances human cholangiocarcinoma growth and chemoresistance by simultaneous activation of Akt and Nrf2 pathways.
Author: Chen, Qiang|Li, Wenjiao|Wan, Yunyan|Xia, Xiaochun|Wu, Qiao|Chen, Yanling|Lai, Zhide|Yu, Chundong|Li, Wengang
PMID: 22213475
Journal: Anticancer Res. 2012 Dec;32(12):5337-42.
Title: Curcumin resistance induced by hypoxia in HepG2 cells is mediated by multidrug-resistance-associated proteins.
Author: Sakulterdkiat, Titipatima|Srisomsap, Chantragan|Udomsangpetch, Rachanee|Svasti, Jisnuson|Lirdprapamongkol, Kriengsak
PMID: 23225435
Journal: Phytomedicine. 2013 Aug 15;20(11):985-91.
Title: Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma.
Author: Wang, Hui|Zhai, Zhenbo|Li, Nanlin|Jin, Haifeng|Chen, Jianghao|Yuan, Shifang|Wang, Ling|Zhang, Juliang|Li, Yongping|Yun, Jun|Fan, Jing|Yi, Jun|Ling, Rui
PMID: 23786867
Journal: J Toxicol Sci. 2013;38(3):403-13.
Title: Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress.
Author: Morita, Reiko|Yafune, Atsunori|Shiraki, Ayako|Itahashi, Megu|Ishii, Yuji|Akane, Hirotoshi|Nakane, Fumiyuki|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi
PMID: 23665939
Journal: Nihon Shokakibyo Gakkai Zasshi. 2014 May;111(5):940-7.
Title: [Three cases of hepatocellular carcinoma with nodules showing different signal intensities in the hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI].
Author: Kita, Ryuichi|Sakamoto, Azusa|Iguchi, Eriko|Takeda, Haruhiko|Oohara, Yoshiaki|Nishijima, Norihiro|Saito, Sumio|Nasu, Akihiro|Nishikawa, Hiroki|Kimura, Toru|Osaki, Yukio|Wakasa, Tomoko|Nakanuma, Yasuni|Matsui, Osamu
PMID: 24806238
Journal: Drug Metab Dispos. 2014 Dec;42(12):2033-40.
Title: Differential expression of drug uptake and efflux transporters in Japanese patients with hepatocellular carcinoma.
Author: Namisaki, Tadashi|Schaeffeler, Elke|Fukui, Hiroshi|Yoshiji, Hitoshi|Nakajima, Yoshiyuki|Fritz, Peter|Schwab, Matthias|Nies, Anne T
PMID: 25231932
Journal: Vet J. 2014 Nov;202(2):255-66.
Title: Classification of primary hepatic tumours in the cat.
Author: van Sprundel, Renee G H M|van den Ingh, Ted S G A M|Guscetti, Franco|Kershaw, Olivia|van Wolferen, Monique E|Rothuizen, Jan|Spee, Bart
PMID: 25439443
Journal: Mol Med Rep. 2015 Sep;12(3):3902-3908.
Title: CSN5 silencing reverses sorafenib resistance of human hepatocellular carcinoma HepG2 cells.
Author: Wang, Haibo|Qian, Zhengyao|Zhao, Hui|Zhang, Xibo|Che, Shuqiang|Zhang, Hongtao|Shang, Haitao|Bao, Jianheng|Hao, Chengfei|Liu, Junjian|Li, Zhonglian
PMID: 26035694
Journal: Biochem Pharmacol. 2015 Dec 15;98(4):703-17.
Title: Protein kinase C-dependent regulation of human hepatic drug transporter expression.
Author: Mayati, Abdullah|Le Vee, Marc|Moreau, Amelie|Jouan, Elodie|Bucher, Simon|Stieger, Bruno|Denizot, Claire|Parmentier, Yannick|Fardel, Olivier
PMID: 26462574
Journal: Biomed Res Int. 2015;2015:752850.
Title: The Chinese Herb Jianpijiedu Contributes to the Regulation of OATP1B2 and ABCC2 in a Rat Model of Orthotopic Transplantation Liver Cancer Pretreated with Food Restriction and Diarrhea.
Author: Sun, Baoguo|Chen, Yan|Xiang, Ting|Zhang, Lei|Chen, Zexiong|Zhang, Shijun|Zhou, Houming|Chen, Shuqing
PMID: 26665149
Journal: Oncol Rep. 2016 May;35(5):2576-82.
Title: Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.
Author: Kataoka, Junro|Shiraha, Hidenori|Horiguchi, Shigeru|Sawahara, Hiroaki|Uchida, Daisuke|Nagahara, Teruya|Iwamuro, Masaya|Morimoto, Hiroki|Takeuchi, Yasuto|Kuwaki, Kenji|Onishi, Hideki|Nakamura, Shinichiro|Takaki, Akinobu|Nouso, Kazuhiro|Yagi, Takahito|Yamam
PMID: 26985715
Journal: Pharmaceutics. 2016 Dec 28;9(1). pii: pharmaceutics9010003.
Title: Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.
Author: Jouan, Elodie|Le Vee, Marc|Denizot, Claire|Parmentier, Yannick|Fardel, Olivier
PMID: 28036031
Journal: Pharmacogenomics. 2016 Sep;17(14):1483-90.
Title: Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity.
Author: Bins, Sander|Lenting, Anne|El Bouazzaoui, Samira|van Doorn, Leni|Oomen-de Hoop, Esther|Eskens, Ferry Alm|van Schaik, Ron Hn|Mathijssen, Ron Hj
PMID: 27533851
Journal: Oncotarget. 2016 Feb 9;7(6):7207-15.
Title: MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma.
Author: Tomonari, Tetsu|Takeishi, Shunsaku|Taniguchi, Tatsuya|Tanaka, Takahiro|Tanaka, Hironori|Fujimoto, Shota|Kimura, Tetsuo|Okamoto, Koichi|Miyamoto, Hiroshi|Muguruma, Naoki|Takayama, Tetsuji
PMID: 26769852
Journal: Biomed Pharmacother. 2017 Aug;92:365-372.
Title: The human RNA surveillance factor Up-frameshift 1 inhibits hepatic cancer progression by targeting MRP2/ABCC2.
Author: Zhang, Hai|You, Yina|Zhu, Zhongliang
PMID: 28554132
Journal: Sci Rep. 2017 Jul 27;7(1):6747.
Title: Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma.
Author: Casagrande, Viviana|Mauriello, Alessandro|Bischetti, Simone|Mavilio, Maria|Federici, Massimo|Menghini, Rossella
PMID: 28751722
Journal: Hepatol Commun. 2017 Apr;1(2):153-167.
Title: Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development.
Author: Jia, Chengyou|Medina, Vivian|Liu, Chenchang|He, Lina|Qian, Daohai|Taojian, Tu|Okamoto, Curtis T|Stiles, Bangyan L
PMID: 29152604
Journal: Food Funct. 2018 May 23;9(5):2684-2694.
Title: Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Author: Gao, Xiaoguang|Wang, Changyuan|Ning, Chenqing|Liu, Kexin|Wang, Xinyuan|Liu, Zhihao|Sun, Huijun|Ma, Xiaodong|Sun, Pengyuan|Meng, Qiang
PMID: 29721568
Journal: Phytomedicine. 2018 Apr 1;43:37-45.
Title: Reversal effect of quercetin on multidrug resistance via FZD7/beta-catenin pathway in hepatocellular carcinoma cells.
Author: Chen, Zhaolin|Huang, Cheng|Ma, Taotao|Jiang, Ling|Tang, Liqin|Shi, Tianlu|Zhang, Shantang|Zhang, Lei|Zhu, Pengli|Li, Jun|Shen, Aizong
PMID: 29747752
Journal: Eur J Pharmacol. 2018 Nov 5;838:91-106.
Title: Evidence that decreased expression of sinusoidal bile acid transporters accounts for the inhibition by rapamycin of bile flow recovery following liver ischemia.
Author: Afroz, Farhana|Jonkman, Els|Hua, Jin|Kist, Alwyn|Zhou, Yabin|Sokoya, Elke M|Padbury, Robert|Nieuwenhuijs, Vincent|Barritt, Greg
PMID: 30179613