Primary Site >> Liver Cancer

Gene >> ABCC2

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Ref: Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake.
PMID: 10699972
Ref: Multiple black hepatocellular adenomas in a male patient.
PMID: 11111785
 Ref: Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.
PMID: 11745434
 Ref: Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.
PMID: 12606785
 Ref: Hepatobiliary transporter expression in human hepatocellular carcinoma.
PMID: 15780063
 Ref: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs.
PMID: 17704753
Ref: The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins.
PMID: 17982673
 Ref: Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer.
PMID: 19451719
Ref: The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
PMID: 19513507
Ref: Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
PMID: 19588995
 Ref: Establishment of a cisplatin-induced multidrug resistance cell line SK-Hep1/DDP.
PMID: 20109345
 Ref: Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
PMID: 22110214
 Ref: Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.
PMID: 21932399
Ref: Amplified in breast cancer 1 enhances human cholangiocarcinoma growth and chemoresistance by simultaneous activation of Akt and Nrf2 pathways.
PMID: 22213475
Ref: Curcumin resistance induced by hypoxia in HepG2 cells is mediated by multidrug-resistance-associated proteins.
PMID: 23225435
 Ref: Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress.
PMID: 23665939
Ref: Steroidal saponin of Trillium tschonoskii. Reverses multidrug resistance of hepatocellular carcinoma.
PMID: 23786867
 Ref: [Three cases of hepatocellular carcinoma with nodules showing different signal intensities in the hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI].
PMID: 24806238
Ref: Differential expression of drug uptake and efflux transporters in Japanese patients with hepatocellular carcinoma.
PMID: 25231932
Ref: Classification of primary hepatic tumours in the cat.
PMID: 25439443
 Ref: CSN5 silencing reverses sorafenib resistance of human hepatocellular carcinoma HepG2 cells.
PMID: 26035694
Ref: Protein kinase C-dependent regulation of human hepatic drug transporter expression.
PMID: 26462574
Ref: The Chinese Herb Jianpijiedu Contributes to the Regulation of OATP1B2 and ABCC2 in a Rat Model of Orthotopic Transplantation Liver Cancer Pretreated with Food Restriction and Diarrhea.
PMID: 26665149
 Ref: MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma.
PMID: 26769852
Ref: Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.
PMID: 26985715
Ref: Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity.
PMID: 27533851
Ref: Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.
PMID: 28036031
 Ref: The human RNA surveillance factor Up-frameshift 1 inhibits hepatic cancer progression by targeting MRP2/ABCC2.
PMID: 28554132
Ref: Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma.
PMID: 28751722
Ref: Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development.
PMID: 29152604
 Ref: Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
PMID: 29721568
Ref: Reversal effect of quercetin on multidrug resistance via FZD7/beta-catenin pathway in hepatocellular carcinoma cells.
PMID: 29747752
Ref: Evidence that decreased expression of sinusoidal bile acid transporters accounts for the inhibition by rapamycin of bile flow recovery following liver ischemia.
PMID: 30179613