Primary Site >> Colorectal Cancer

Gene >> ABCB1

Journal: Tumori. 1989 Dec 31;75(6):542-6.
Title: Detection of the 170 kDa P-glycoprotein in neoplastic and normal tissues.
Author: Ronchi, E|Sanfilippo, O|Di Fronzo, G|Bani, M R|Della Torre, G|Catania, S|Silvestrini, R
PMID: 2575816
Journal: J Natl Cancer Inst. 1990 Feb 7;82(3):193-8.
Title: Chemosensitivity patterns and expression of human multidrug resistance-associated MDR1 gene by human gastric and colorectal carcinoma cell lines.
Author: Park, J G|Kramer, B S|Lai, S L|Goldstein, L J|Gazdar, A F
PMID: 1967320
Journal: J Natl Cancer Inst. 1990 Nov 7;82(21):1679-83.
Title: Expression of the MDR1 gene in human gastric and colorectal carcinomas.
Author: Mizoguchi, T|Yamada, K|Furukawa, T|Hidaka, K|Hisatsugu, T|Shimazu, H|Tsuruo, T|Sumizawa, T|Akiyama, S
PMID: 1977924
Journal: Hiroshima J Med Sci. 1990 Sep;39(3):71-7.
Title: Expression of the multidrug resistance gene in human tumors.
Author: Kim, R
PMID: 1980915
Journal: Princess Takamatsu Symp. 1990;21:241-51.
Title: Multidrug resistance: a transport system of antitumor agents and xenobiotics.
Author: Tsuruo, T
PMID: 1983721
Journal: Br J Cancer. 1991 Jan;63(1):51-6.
Title: Pleiotropic-resistant phenotype is a multifactorial phenomenon in human colon carcinoma cell lines.
Author: Toffoli, G|Viel, A|Tumiotto, L|Biscontin, G|Rossi, C|Boiocchi, M
PMID: 1671208
Journal: Anticancer Res. 1991 May-Jun;11(3):1309-12.
Title: Establishment of multidrug resistant human colorectal carcinoma HCT-15 cell lines and their properties.
Author: Iwahashi, T|Okochi, E|Ono, K|Sugawara, I|Tsuruo, T|Mori, S
PMID: 1679619
Journal: J Natl Cancer Inst. 1991 Oct 2;83(19):1386-91.
Title: Reversal of drug resistance in a human colon cancer xenograft expressing MDR1 complementary DNA by in vivo administration of MRK-16 monoclonal antibody.
Author: Pearson, J W|Fogler, W E|Volker, K|Usui, N|Goldenberg, S K|Gruys, E|Riggs, C W|Komschlies, K|Wiltrout, R H|Tsuruo, T
PMID: 1681110
Journal: Cancer Res. 1991 Nov 15;51(22):6039-44.
Title: Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells.
Author: Chen, A Y|Yu, C|Potmesil, M|Wall, M E|Wani, M C|Liu, L F
PMID: 1682041
Journal: FEBS Lett. 1991 Oct 21;291(2):214-8.
Title: Co-amplification and over-expression of two mdr genes in a multidrug-resistant human colon carcinoma cell line.
Author: Chao, C C|Ma, C M|Lin-Chao, S
PMID: 1682162
Journal: Cancer Res. 1991 Oct 1;51(19):5275-83.
Title: Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines.
Author: Long, B H|Wang, L|Lorico, A|Wang, R C|Brattain, M G|Casazza, A M
PMID: 1717144
Journal: Anticancer Res. 1992 Jan-Feb;12(1):241-5.
Title: Factors contributing to adriamycin sensitivity in human xenograft tumors: the relationship between expression of the MDR1, GST-pi and topoisomerase II genes and tumor sensitivity to adriamycin.
Author: Kim, R|Hirabayashi, N|Nishiyama, M|Jinushi, K|Toge, T|Okada, K
PMID: 1314532
Journal: Mol Pharmacol. 1992 Jan;41(1):69-75.
Title: Overexpression of glutathione S-transferase and elevation of thiol pools in a multidrug-resistant human colon cancer cell line.
Author: Chao, C C|Huang, Y T|Ma, C M|Chou, W Y|Lin-Chao, S
PMID: 1346333
Journal: J Natl Cancer Inst. 1992 May 6;84(9):711-6.
Title: Various methods of analysis of mdr-1/P-glycoprotein in human colon cancer cell lines.
Author: Herzog, C E|Trepel, J B|Mickley, L A|Bates, S E|Fojo, A T
PMID: 1349044
Journal: Eur J Cancer. 1992;28A(6-7):1099-105.
Title: Mechanism of multidrug resistance in human tumour cell lines and complete reversion of cellular resistance.
Author: Boiocchi, M|Toffoli, G
PMID: 1352696
Journal: Tumori. 1992 Jun 30;78(3):159-66.
Title: P-glycoprotein but not topoisomerase II and glutathione-S-transferase-pi accounts for enhanced intracellular drug-resistance in LoVo MDR human cell lines.
Author: Boiocchi, M|Tumiotto, L|Giannini, F|Viel, A|Biscontin, G|Sartor, F|Toffoli, G
PMID: 1359686
Journal: J Natl Cancer Inst. 1992 Dec 16;84(24):1909-15.
Title: Liposome-mediated modulation of multidrug resistance in human HL-60 leukemia cells.
Author: Rahman, A|Husain, S R|Siddiqui, J|Verma, M|Agresti, M|Center, M|Safa, A R|Glazer, R I
PMID: 1361008
Journal: Cancer Chemother Pharmacol. 1992;29(4):283-9.
Title: Expression of the mdr1 gene in human colorectal carcinomas: relationship with multidrug resistance inferred from analysis of human colorectal carcinoma cell lines.
Author: Toffoli, G|Viel, A|Tumiotto, L|Maestro, R|Biscontin, G|Boiocchi, M
PMID: 1537074
Journal: Cancer Res. 1992 Jul 1;52(13):3655-60.
Title: Effect of a dihydropyridine analogue, 2-[benzyl(phenyl)amino]ethyl 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-2-oxo- 1,3,2-dioxaphosphorinan-2-yl)-1-(2-morpholinoethyl)-4-(3-nitrophenyl)-3 -pyridinecarboxylate on reversing in vivo resistance of tumor cells
Author: Niwa, K|Yamada, K|Furukawa, T|Shudo, N|Seto, K|Matsumoto, T|Takao, S|Akiyama, S|Shimazu, H
PMID: 1617639
Journal: Cancer. 1992 Feb 15;69(4):941-6.
Title: Expression of MDR1 and glutathione S transferase-pi genes and chemosensitivities in human gastrointestinal cancer.
Author: Satta, T|Isobe, K|Yamauchi, M|Nakashima, I|Takagi, H
PMID: 1735085
Journal: Int J Cancer. 1993 Feb 20;53(4):680-8.
Title: The development and characterization of Vinca alkaloid-resistant Caco-2 human colorectal cell lines expressing mdr-1.
Author: Hoskins, J|DeHerdt, S V|Moore, R E|Bumol, T F
PMID: 8094716
Journal: Br J Cancer. 1993 May;67(5):959-68.
Title: Constitutive expression of multidrug resistance in human colorectal tumours and cell lines.
Author: Kramer, R|Weber, T K|Morse, B|Arceci, R|Staniunas, R|Steele, G Jr|Summerhayes, I C
PMID: 8098614
Journal: Int J Cancer. 1993 Sep 9;55(2):297-302.
Title: Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines.
Author: Frommel, T O|Coon, J S|Tsuruo, T|Roninson, I B
PMID: 8103760
Journal: Gan To Kagaku Ryoho. 1993 Apr;20(6):831-3.
Title: [Analysis of MDR1 (multidrug resistance) gene expression by RT-PCR].
Author: Nakashima, A|Okabayashi, T|Nakatani, S|Kataoka, M|Johira, H|Takeda, A|Orita, K
PMID: 8387754
Journal: Eur J Cancer. 1993;29A(12):1776-8.
Title: Increased chemosensitivity to doxorubicin of intrinsically multidrug-resistant human colon carcinoma cells by prolonged exposure to verapamil.
Author: Toffoli, G|Tumiotto, L|Gigante, M|Dall'Arche, M G|Perin, T|Boiocchi, M
PMID: 8398309
Journal: Br J Cancer. 1993 Oct;68(4):691-4.
Title: MDR1 gene expression in primary colorectal carcinomas.
Author: Pirker, R|Wallner, J|Gsur, A|Gotzl, M|Zochbauer, S|Scheithauer, W|Depisch, D
PMID: 8398695
Journal: Stem Cells. 1993 Jul;11(4):276-82.
Title: Neuroblastoma: the result of multistep transformation?
Author: Tonini, G P
PMID: 8401251
Journal: Oncol Res. 1994;6(7):291-301.
Title: P-glycoprotein mediates profound resistance to bisantrene.
Author: Zhang, X P|Ritke, M K|Yalowich, J C|Slovak, M L|Ho, J P|Collins, K I|Annable, T|Arceci, R J|Durr, F E|Greenberger, L M
PMID: 7865904
Journal: J Biol Chem. 1994 Apr 8;269(14):10739-46.
Title: Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells.
Author: Morrow, C S|Nakagawa, M|Goldsmith, M E|Madden, M J|Cowan, K H
PMID: 7908296
Journal: J Clin Oncol. 1994 Apr;12(4):812-9.
Title: Clinical and pharmacologic study of multidrug resistance reversal with vinblastine and bepridil.
Author: Linn, S C|van Kalken, C K|van Tellingen, O|van der Valk, P|van Groeningen, C J|Kuiper, C M|Pinedo, H M|Giaccone, G
PMID: 7908691
Journal: Anticancer Res. 1994 May-Jun;14(3A):857-68.
Title: In vivo expression of P-glycoprotein in a human colon carcinoma xenograft is modulated by therapy with free and monoclonal antibody-conjugated vinca alkaloids.
Author: Hilselberger Kanitz, M|Mastro, J M|Moore, R E|Starling, J J
PMID: 7915508
Journal: Cancer. 1994 Dec 1;74(11):2908-17.
Title: Relationship of P-glycoprotein and carcinoembryonic antigen expression in human colon carcinoma to local invasion, DNA ploidy, and disease relapse.
Author: Sinicrope, F A|Hart, J|Brasitus, T A|Michelassi, F|Lee, J J|Safa, A R
PMID: 7954255
Journal: J Cancer Res Clin Oncol. 1994;120(8):471-8.
Title: Influence of cytokines on mdr1 expression in human colon carcinoma cell lines: increased cytotoxicity of MDR relevant drugs.
Author: Walther, W|Stein, U
PMID: 8207045
Journal: Adv Pharmacol. 1994;29B:245-56.
Title: Design of topoisomerase inhibitors to overcome MDR1-mediated drug resistance.
Author: Chen, A Y|Liu, L F
PMID: 8996611
Journal: Int J Oncol. 1994 Feb;4(2):423-7.
Title: Phorbol 12-myristate 13-acetate (pma) induces neuroendocrine-like differentiation and reverses Doxorubicin-resistance of human colon-carcinoma cells in-vitro.
Author: Correale, P|Caraglia, M|Pepe, S|Ricciardi, B|Barile, C|Montagnani, S|Pacelli, R|Bianco, A|Tagliaferri, P
PMID: 21566941
Journal: Mol Pharmacol. 1995 Oct;48(4):682-9.
Title: A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line.
Author: Bhat, U G|Winter, M A|Pearce, H L|Beck, W T
PMID: 7476894
Journal: Biochem Pharmacol. 1995 Oct 12;50(8):1245-55.
Title: Structure-activity relationship of verapamil analogs and reversal of multidrug resistance.
Author: Toffoli, G|Simone, F|Corona, G|Raschack, M|Cappelletto, B|Gigante, M|Boiocchi, M
PMID: 7488241
Journal: Lab Invest. 1995 Jun;72(6):760-4.
Title: Immunomagnetic purification of human breast carcinoma cells allows tumor-specific detection of multidrug resistance gene 1-mRNA by reverse transcriptase polymerase chain reaction in fine-needle aspirates.
Author: Maas, R A|Bruning, P F|Breedijk, A J|Top, B|Peterse, H L
PMID: 7540237
Journal: FEBS Lett. 1995 Jul 17;368(2):373-6.
Title: Cell-specific effects of RAS oncogene and protein kinase C agonist TPA on P-glycoprotein function.
Author: Stromskaya, T P|Grigorian, I A|Ossovskaya, V S|Rybalkina, E Y|Chumakov, P M|Kopnin, B P
PMID: 7628641
Journal: Cancer Res. 1995 Oct 1;55(19):4214-9.
Title: The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification.
Author: Slovak, M L|Ho, J P|Cole, S P|Deeley, R G|Greenberger, L|de Vries, E G|Broxterman, H J|Scheffer, G L|Scheper, R J
PMID: 7671223
Journal: J Natl Cancer Inst. 1995 Jan 18;87(2):123-8.
Title: Reversal of multidrug resistance in human colon cancer cells expressing the human MDR1 gene by liposomes in combination with monoclonal antibody or verapamil.
Author: Sela, S|Husain, S R|Pearson, J W|Longo, D L|Rahman, A
PMID: 7707383
Journal: J Natl Cancer Inst. 1995 Jan 18;87(2):94-104.
Title: Enhancement by recombinant human interferon alfa of the reversal of multidrug resistance by MRK-16 monoclonal antibody.
Author: Fogler, W E|Pearson, J W|Volker, K|Ariyoshi, K|Watabe, H|Riggs, C W|Wiltrout, R H|Longo, D L
PMID: 7707396
Journal: Jpn J Cancer Res. 1995 Feb;86(2):224-32.
Title: Acute induction of adriamycin-resistance in human colon carcinoma HT-29 cells exposed to a sublethal dose of adriamycin.
Author: Tomida, A|Naito, M|Tsuruo, T
PMID: 7730148
Journal: Int J Cancer. 1995 Jun 9;61(6):873-9.
Title: Circumvention of confluence-dependent resistance in a human multi-drug-resistant colon-cancer cell line.
Author: Garrido, C|Chauffert, B|Pinard, D|Tibaut, F|Genne, P|Assem, M|Dimanche-Boitrel, M T
PMID: 7790124
Journal: J Cancer Res Clin Oncol. 1996;122(5):275-82.
Title: Vincristine induction of mutant and wild-type human multidrug-resistance promoters is cell-type-specific and dose-dependent.
Author: Stein, U|Walther, W|Shoemaker, R H
PMID: 8609150
Journal: Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4001-5.
Title: P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
Author: Schuetz, E G|Schinkel, A H|Relling, M V|Schuetz, J D
PMID: 8633005
Journal: J Natl Cancer Inst. 1996 Jun 5;88(11):747-53.
Title: Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease.
Author: Rybak, S M|Pearson, J W|Fogler, W E|Volker, K|Spence, S E|Newton, D L|Mikulski, S M|Ardelt, W|Riggs, C W|Kung, H F|Longo, D L
PMID: 8637029
Journal: Biochem Pharmacol. 1996 Jul 12;52(1):127-31.
Title: Expression of the low-density lipoprotein receptor, HMG-CoA reductase, and multidrug resistance (Mdr1) genes in colorectal carcinomas.
Author: Vitols, S|Gunven, P|Gruber, A|Larsson, O
PMID: 8678896
Journal: J Cell Biochem Suppl. 1996;24:131-41.
Title: Biology of colorectal and gastric cancer cell lines.
Author: Park, J G|Gazdar, A F
PMID: 8806095
Journal: J Natl Cancer Inst. 1996 Oct 2;88(19):1383-92.
Title: Reversal of multidrug resistance by transduction of cytokine genes into human colon carcinoma cells.
Author: Stein, U|Walther, W|Shoemaker, R H
PMID: 8827016
Journal: J Cancer Res Clin Oncol. 1996;122(11):671-5.
Title: MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases.
Author: de Kant, E|Heide, I|Thiede, C|Herrmann, R|Rochlitz, C F
PMID: 8898977
Journal: Br J Cancer. 1996 Nov;74(9):1384-91.
Title: Modulation of mdr1 expression by cytokines in human colon carcinoma cells: an approach for reversal of multidrug resistance.
Author: Stein, U|Walther, W|Shoemaker, R H
PMID: 8912533
Journal: Chin Med Sci J. 1996 Mar;11(1):17-20.
Title: The amplification and expression of MDR1 gene in adriamycine resistant cell line of colon cancer cell HR8348.
Author: Zhou, Z|Luo, X|Lin, C|Chen, F
PMID: 9206112
Journal: Int J Oncol. 1996 Jun;8(6):1095-104.
Title: Anti-tumor ribonuclease, combined with or conjugated to monoclonal antibody MRK16, overcomes multidrug resistance to vincristine in vitro and in vivo.
Author: Newton, D|Pearson, J|Xue, Y|Smith, M|Fogler, W|Mikulski, S|Alvord, W|Kung, H|Long, D|Rybak, S
PMID: 21544469
Journal: J Biol Chem. 1997 Apr 25;272(17):11518-25.
Title: Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway.
Author: Furuya, K N|Thottassery, J V|Schuetz, E G|Sharif, M|Schuetz, J D
PMID: 9111066
Journal: Mol Pharmacol. 1997 May;51(5):741-54.
Title: Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
Author: Schmiedlin-Ren, P|Thummel, K E|Fisher, J M|Paine, M F|Lown, K S|Watkins, P B
PMID: 9145912
Journal: Anticancer Res. 1997 May-Jun;17(3C):2065-71.
Title: Suramin is synergistic with vinblastine in human colonic tumor cell lines: effect of cell density and timing of drug delivery.
Author: Frommel, T O
PMID: 9216665
Journal: Gene Ther. 1997 Jun;4(6):544-52.
Title: Employment of the mdr1 promoter for the chemotherapy-inducible expression of therapeutic genes in cancer gene therapy.
Author: Walther, W|Wendt, J|Stein, U
PMID: 9231070
Journal: J Cancer Res Clin Oncol. 1997;123(8):452-5.
Title: Treatment of advanced colorectal cancer with doxorubicin combined with two potential multidrug-resistance-reversing agents: high-dose oral tamoxifen and dexverapamil.
Author: Weinlander, G|Kornek, G|Raderer, M|Hejna, M|Tetzner, C|Scheithauer, W
PMID: 9292709
Journal: Eur J Cancer. 1997 Aug;33(9):1516-8.
Title: MDR1 RNA transcripts do not indicate long-term prognosis in colorectal carcinomas.
Author: Zochbauer, S|Wallner, J|Haider, K|Depisch, D|Huber, H|Pirker, R
PMID: 9337699
Journal: Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11037-42.
Title: p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents.
Author: Thottassery, J V|Zambetti, G P|Arimori, K|Schuetz, E G|Schuetz, J D
PMID: 9380755
Journal: Biochem Biophys Res Commun. 1997 Nov 26;240(3):606-11.
Title: Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells.
Author: Narasaki, F|Oka, M|Nakano, R|Ikeda, K|Fukuda, M|Nakamura, T|Soda, H|Nakagawa, M|Kuwano, M|Kohno, S
PMID: 9398612
Journal: Invest New Drugs. 1997;15(4):311-8.
Title: Potent induction of human colon cancer cell uptake of chemotherapeutic drugs by N-myristoylated protein kinase C-alpha (PKC-alpha) pseudosubstrate peptides through a P-glycoprotein-independent mechanism.
Author: Bergman, P J|Gravitt, K R|Ward, N E|Beltran, P|Gupta, K P|O'Brian, C A
PMID: 9547673
Journal: Oncol Res. 1998;10(1):29-41.
Title: Characterization of 2-chloro-N10-substituted phenoxazines for reversing multidrug resistance in cancer cells.
Author: Thimmaiah, K N|Jayashree, B S|Germain, G S|Houghton, P J|Horton, J K
PMID: 9613455
Journal: Mol Cell Biol. 1998 Jul;18(7):4377-84.
Title: Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.
Author: Jin, S|Scotto, K W
PMID: 9632821
Journal: J Pharmacol Exp Ther. 1998 Jul;286(1):419-28.
Title: Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression.
Author: Alahari, S K|DeLong, R|Fisher, M H|Dean, N M|Viliet, P|Juliano, R L
PMID: 9655887
Journal: Biochem Biophys Res Commun. 1998 Aug 10;249(1):6-10.
Title: Cellular resistance to adriamycin conferred by enhanced Rb expression is associated with increased MDR1 expression.
Author: Yoo, Y D|Kang, S|Kang, Y K
PMID: 9705821
Journal: Genes Chromosomes Cancer. 1998 Sep;23(1):44-54.
Title: Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.
Author: Knutsen, T|Mickley, L A|Ried, T|Green, E D|du Manoir, S|Schrock, E|Macville, M|Ning, Y|Robey, R|Polymeropoulos, M|Torres, R|Fojo, T
PMID: 9713996
Journal: Eur J Cancer. 1998 May;34(6):908-13.
Title: Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft.
Author: Kelner, M J|McMorris, T C|Estes, L|Samson, K M|Bagnell, R D|Taetle, R
PMID: 9797706
Journal: Int J Cancer. 1999 Jan 5;80(1):5-12.
Title: Hyperthermia for treatment of rectal cancer: evaluation for induction of multidrug resistance gene (mdr1) expression.
Author: Stein, U|Rau, B|Wust, P|Walther, W|Schlag, P M
PMID: 9935221
Journal: Biochem Biophys Res Commun. 1999 May 27;259(1):43-9.
Title: Multidrug-resistant phenotype influences the differentiation of a human colon carcinoma cell line.
Author: Rimet, O|Mirrione, A|Barra, Y
PMID: 10334913
Journal: Biol Cell. 1999 Mar;91(2):143-55.
Title: Follicle-like structures formed by intestinal cell lines derived from the HT29-D4 adenocarcinoma cell line: morphological and functional characterization.
Author: Mirrione, A|Mauchamp, J|Rimet, O|Roccabianca, M|Barra, Y|Alquier, C
PMID: 10399829
Journal: Int J Cancer. 1999 Jul 30;82(3):346-52.
Title: Tumor-specific expression of anti-mdr1 ribozyme selectively restores chemosensitivity in multidrug-resistant colon-adenocarcinoma cells.
Author: Gao, Z|Gao, Z|Fields, J Z|Boman, B M
PMID: 10399951
Journal: Clin Cancer Res. 2000 Feb;6(2):643-53.
Title: Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts.
Author: Poirson-Bichat, F|Goncalves, R A|Miccoli, L|Dutrillaux, B|Poupon, M F
PMID: 10690550
Journal: Clin Cancer Res. 2000 Jun;6(6):2401-7.
Title: Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas.
Author: Hinoshita, E|Uchiumi, T|Taguchi, K|Kinukawa, N|Tsuneyoshi, M|Maehara, Y|Sugimachi, K|Kuwano, M
PMID: 10873092
Journal: Pharmacology. 2000 Sep;61(3):212-27.
Title: Molecular genetics of cancer susceptibility.
Author: Brockmoller, J|Cascorbi, I|Henning, S|Meisel, C|Roots, I
PMID: 10971208
Journal: Cancer Res. 2000 Sep 1;60(17):4761-6.
Title: Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis.
Author: Yamada, T|Takaoka, A S|Naishiro, Y|Hayashi, R|Maruyama, K|Maesawa, C|Ochiai, A|Hirohashi, S
PMID: 10987283
Journal: Rev Physiol Biochem Pharmacol. 2001;142:1-96.
Title: Modulation of protein kinase C in antitumor treatment.
Author: Hofmann, J
PMID: 11190577
Journal: Pflugers Arch. 2001 Jan;441(4):529-37.
Title: Identification of an organic anion transport system in the human colon carcinoma cell line HT29 clone 19A.
Author: Abrahamse, S L|Rechkemmer, G
PMID: 11212217
Journal: Cancer Res. 2001 Feb 15;61(4):1693-8.
Title: Drug resistance induced by ouabain via the stimulation of MDR1 gene expression in human carcinomatous pulmonary cells.
Author: Brouillard, F|Tondelier, D|Edelman, A|Baudouin-Legros, M
PMID: 11245485
Journal: J Biol Chem. 2001 May 4;276(18):14581-7. Epub 2001 Jan 31.
Title: Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Author: Geick, A|Eichelbaum, M|Burk, O
PMID: 11297522
Journal: Cancer Lett. 2001 Jun 10;167(1):91-7.
Title: Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features.
Author: Shannon, B A|Iacopetta, B J
PMID: 11323103
Journal: J Nucl Med. 2001 Apr;42(4):646-54.
Title: In vitro and in vivo tracer characteristics of an established multidrug-resistant human colon cancer cell line.
Author: Lorke, D E|Kruger, M|Buchert, R|Bohuslavizki, K H|Clausen, M|Schumacher, U
PMID: 11337555
Journal: J Biol Chem. 2001 Jul 27;276(30):28562-9.
Title: Hyperthermia-induced nuclear translocation of transcription factor YB-1 leads to enhanced expression of multidrug resistance-related ABC transporters.
Author: Stein, U|Jurchott, K|Walther, W|Bergmann, S|Schlag, P M|Royer, H D
PMID: 11369762
Journal: Oncol Rep. 2001 Jul-Aug;8(4):815-9.
Title: Effects of MDR1/P-glycoprotein expression on prognosis in advanced colorectal cancer after surgery.
Author: Tokunaga, Y|Hosogi, H|Hoppou, T|Nakagami, M|Tokuka, A|Ohsumi, K
PMID: 11410790
Journal: Biochem Biophys Res Commun. 2001 Aug 17;286(2):406-13.
Title: Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression.
Author: Nagata, J|Kijima, H|Hatanaka, H|Asai, S|Miyachi, H|Takagi, A|Miwa, T|Mine, T|Yamazaki, H|Nakamura, M|Kondo, T|Scanlon, K J|Ueyama, Y
PMID: 11500053
Journal: Anticancer Drugs. 2001 Oct;12(9):769-79.
Title: Establishment and characterization of adriamycin-resistant human colorectal adenocarcinoma HCT-15 cell lines with multidrug resistance.
Author: Uchiyama-Kokubu, N|Watanabe, T
PMID: 11593059
Journal: Pflugers Arch. 2001;442(6 Suppl 1):R182-3.
Title: The role of P-glycoprotein (MDR1) polymorphisms and mutations in colorectal cancer.
Author: Potocnik, U|Glavac, M R|Golouh, R|Glavac, D
PMID: 11678332
Journal: Int J Cancer. 2002 Mar 10;98(2):291-6.
Title: Use of the human MDR1 promoter for heat-inducible expression of therapeutic genes.
Author: Walther, Wolfgang|Stein, Ulrike|Schlag, Peter M
PMID: 11857422
Journal: Biochem Biophys Res Commun. 2002 Mar 22;292(1):190-4.
Title: Digoxin up-regulates MDR1 in human colon carcinoma Caco-2 cells.
Author: Takara, Kohji|Tsujimoto, Masayuki|Ohnishi, Noriaki|Yokoyama, Teruyoshi
PMID: 11890691
Journal: Mol Pharmacol. 2002 Apr;61(4):879-84.
Title: Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine.
Author: Kang, Mi Ran|Chung, In Kwon
PMID: 11901227
Journal: Cell Mol Biol Lett. 2002;7(1):92-5.
Title: Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.
Author: Potocnik, Uros|Ravnik-Glavac, Metka|Glavac, Damjan
PMID: 11980438
Journal: Hepatology. 2002 Oct;36(4 Pt 1):874-84.
Title: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes.
Author: Huesker, Matthes|Folmer, Yvonne|Schneider, Michaela|Fulda, Christine|Blum, Hubert E|Hafkemeyer, Peter
PMID: 12297834
Journal: Int J Oncol. 2002 Nov;21(5):1021-6.
Title: Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene.
Author: Nagata, Junko|Kijima, Hiroshi|Hatanaka, Hiroyuki|Asai, Satomi|Miyachi, Hayato|Abe, Yoshiyuki|Yamazaki, Hitoshi|Nakamura, Masato|Watanabe, Norihito|Mine, Tetsuya|Kondo, Takahito|Scanlon, Kevin J|Ueyama, Yoshito
PMID: 12370750
Journal: Di Yi Jun Yi Da Xue Xue Bao. 2002 Jul;22(7):626-8.
Title: Effect of protein kinase C on multidrug resistance of multidrug-resistant colorectal cancer LoVo/Adr cells.
Author: Ma, Qiang|Zhang, Zhen-Shu|Zhang, Ya-Li|Wang, Qun-Ying|Lai, Zhuo-Sheng
PMID: 12376294
Journal: Mol Cancer Ther. 2002 Dec;1(14):1327-34.
Title: Overcoming multidrug drug resistance in P-glycoprotein/MDR1-overexpressing cell lines by ecteinascidin 743.
Author: Kanzaki, Atsuko|Takebayashi, Yuji|Ren, Xiao-Qin|Miyashita, Hitoshi|Mori, Shiro|Akiyama, Shin-ichi|Pommier, Yves
PMID: 12516966
Journal: Oncogene. 2003 Jan 9;22(1):90-7.
Title: NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells.
Author: Bentires-Alj, Mohamed|Barbu, Veronique|Fillet, Marianne|Chariot, Alain|Relic, Biserka|Jacobs, Nathalie|Gielen, Jacques|Merville, Marie-Paule|Bours, Vincent
PMID: 12527911
Journal: Int J Radiat Oncol Biol Phys. 2003 Mar 15;55(4):1051-65.
Title: Radiation therapy depletes extrachromosomally amplified drug resistance genes and oncogenes from tumor cells via micronuclear capture of episomes and double minute chromosomes.
Author: Schoenlein, Patricia V|Barrett, John T|Kulharya, A|Dohn, Michael R|Sanchez, Ana|Hou, D-Y|McCoy, J
PMID: 12605985
Journal: Mol Pharmacol. 2003 Mar;63(3):742-50.
Title: Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.
Author: Briz, Oscar|Macias, Rocio I R|Vallejo, Marta|Silva, Augusto|Serrano, Maria Angeles|Marin, Jose J G
PMID: 12606785
Journal: J Pharm Pharmacol. 2003 Jan;55(1):59-66.
Title: Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
Author: Pfrunder, Arabelle|Gutmann, Heike|Beglinger, Christoph|Drewe, Jurgen
PMID: 12625868
Journal: Pharm Res. 2003 Feb;20(2):324-7.
Title: Gene expression profiles of ABC transporters and cytochrome P450 3A in Caco-2 and human colorectal cancer cell lines.
Author: Nakumura, Tsutomu|Sakaeda, Toshiyuki|Ohmoto, Nobuko|Moriya, Yuka|Komoto, Chiho|Shirakawa, Toshiro|Gotoh, Akinobu|Matsuo, Masafumi|Okmura, Katsuhiko
PMID: 12636175
Journal: Pharmacotherapy. 2003 Apr;23(4):436-42.
Title: Evaluation of P-glycoprotein-mediated renal drug interactions in an MDR1-MDCK model.
Author: Karyekar, Chetan S|Eddington, Natalie D|Garimella, Tushar S|Gubbins, Paul O|Dowling, Thomas C
PMID: 12680473
Journal: Biochem Biophys Res Commun. 2003 Jun 20;306(1):116-20.
Title: Digoxin up-regulates multidrug resistance transporter (MDR1) mRNA and simultaneously down-regulates steroid xenobiotic receptor mRNA.
Author: Takara, Kohji|Takagi, Kentaro|Tsujimoto, Masayuki|Ohnishi, Noriaki|Yokoyama, Teruyoshi
PMID: 12788075
Journal: Mol Pharmacol. 2003 Aug;64(2):382-94.
Title: Molecular modes of action of artesunate in tumor cell lines.
Author: Efferth, Thomas|Sauerbrey, Axel|Olbrich, Armin|Gebhart, Erich|Rauch, Pia|Weber, H Oliver|Hengstler, Jan G|Halatsch, Marc-Eric|Volm, Manfred|Tew, Kenneth D|Ross, Douglas D|Funk, Jens Oliver
PMID: 12869643
Journal: Anticancer Res. 2003 May-Jun;23(3B):2681-90.
Title: Effect of MDR1 phosphorothioate antisense oligodeoxynucleotides in multidrug-resistant human tumor cell lines and xenografts.
Author: Ramachandran, Cheppail|Wellham, Larry L
PMID: 12894558
Journal: Anticancer Res. 2003 May-Jun;23(3B):2735-40.
Title: MDR1 single nucleotide polymorphism C3435T in normal colorectal tissue and colorectal carcinomas detected by MALDI-TOF mass spectrometry.
Author: Humeny, A|Rodel, F|Rodel, C|Sauer, R|Fuzesi, L|Becker, C|Efferth, T
PMID: 12894567
Journal: World J Gastroenterol. 2004 Jul 1;10(13):1979-83.
Title: Reversal of 5-flouroucial resistance by adenovirus-mediated transfer of wild-type p53 gene in multidrug-resistant human colon carcinoma LoVo/5-FU cells.
Author: Yu, Zhi-Wei|Zhao, Peng|Liu, Ming|Dong, Xin-Shu|Tao, Ji|Yao, Xue-Qin|Yin, Xin-Hua|Li, Yu|Fu, Song-Bin
PMID: 15222051
Journal: Pharm Res. 2004 Jul;21(7):1284-93.
Title: P-glycoprotein (P-gp/MDR1)-mediated efflux of sex-steroid hormones and modulation of P-gp expression in vitro.
Author: Kim, Winnie Y|Benet, Leslie Z
PMID: 15290871
Journal: Biol Pharm Bull. 2004 Oct;27(10):1694-6.
Title: Effect of rabeprazole on MDR1-mediated transport of Rhodamine 123 in Caco-2 and Hvr100-6 cells.
Author: Itagaki, Fumio|Homma, Masato|Takara, Kohji|Ohnishi, Noriaki|Yokoyama, Teruyoshi|Sakaeda, Toshiyuki|Yagami, Tatsurou|Kobayashi, Hironao|Okamura, Noboru|Kohda, Yukinao
PMID: 15467223
Journal: Br J Pharmacol. 2004 Dec;143(7):856-64.
Title: Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.
Author: Honda, Yoko|Ushigome, Fumihiko|Koyabu, Noriko|Morimoto, Satoshi|Shoyama, Yukihiro|Uchiumi, Takeshi|Kuwano, Michihiko|Ohtani, Hisakazu|Sawada, Yasufumi
PMID: 15504753
Journal: Br J Cancer. 2005 Jan 31;92(2):259-64.
Title: Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.
Author: Glasgow, S C|Yu, J|Carvalho, L P|Shannon, W D|Fleshman, J W|McLeod, H L
PMID: 15655543
Journal: World J Gastroenterol. 2005 Feb 21;11(7):1060-4.
Title: Tamoxifen can reverse multidrug resistance of colorectal carcinoma in vivo.
Author: Shen, Li-Zong|Hua, Yi-Bing|Yu, Xue-Ming|Xu, Qing|Chen, Tao|Wang, Jian-Hua|Wu, Wen-Xi
PMID: 15742416
Journal: In Vivo. 2005 Mar-Apr;19(2):433-8.
Title: Effects of selected flavonoids and carotenoids on drug accumulation and apoptosis induction in multidrug-resistant colon cancer cells expressing MDR1/LRP.
Author: Ugocsai, Katalin|Varga, Andreas|Molnar, Peter|Antus, Sandor|Molnar, Joseph
PMID: 15796208
Journal: Eur J Clin Pharmacol. 2005 Jul;61(5-6):389-94. Epub 2005 May 24.
Title: Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients.
Author: Kurzawski, Mateusz|Drozdzik, Marek|Suchy, Janina|Kurzawski, Grzegorz|Bialecka, Monika|Gornik, Wanda|Lubinski, Jan
PMID: 15912392
Journal: Am J Pathol. 2005 Jun;166(6):1793-806.
Title: Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia.
Author: Maggio-Price, Lillian|Bielefeldt-Ohmann, Helle|Treuting, Piper|Iritani, Brian M|Zeng, Weiping|Nicks, Andrea|Tsang, Mark|Shows, Donna|Morrissey, Phil|Viney, Joanne L
PMID: 15920164
Journal: Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title: Molecular markers that predict response to colon cancer therapy.
Author: Ahmed, Farid E
PMID: 15934813
Journal: BMC Cancer. 2005 Jul 18;5:78.
Title: Cancer cell adaptation to chemotherapy.
Author: Di Nicolantonio, Federica|Mercer, Stuart J|Knight, Louise A|Gabriel, Francis G|Whitehouse, Pauline A|Sharma, Sanjay|Fernando, Augusta|Glaysher, Sharon|Di Palma, Silvana|Johnson, Penny|Somers, Shaw S|Toh, Simon|Higgins, Bernie|Lamont, Alan|Gulliford, Tim|H
PMID: 16026610
Journal: Eur J Cancer. 2005 Aug;41(12):1811-8.
Title: Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136.
Author: Guichard, S M|Macpherson, J S|Thurston, D E|Jodrell, D I
PMID: 16046116
Journal: Anticancer Res. 2005 Jul-Aug;25(4):2661-8.
Title: Gene expression profiling in chemoresistant variants of three cell lines of different origin.
Author: Johnsson, Anders|Vallon-Christensson, Johan|Strand, Carina|Litman, Thomas|Eriksen, Jens
PMID: 16080509
Journal: Cancer Lett. 2006 Mar 8;234(1):90-106.
Title: Role of pharmacogenetics in irinotecan therapy.
Author: de Jong, Floris A|de Jonge, Maja J A|Verweij, Jaap|Mathijssen, Ron H J
PMID: 16343744
Journal: Hum Mol Genet. 2006 Mar 1;15(5):797-805.
Title: ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.
Author: Ho, G-T|Soranzo, N|Nimmo, E R|Tenesa, A|Goldstein, D B|Satsangi, J
PMID: 16434479
Journal: Korean J Gastroenterol. 2006 Jan;47(1):22-9.
Title: [Is C3435T polymorphism of MDR1 related to inflammatory bowel disease or colorectal cancer in Korean?].
Author: Lee, Bo-In|Choi, Kyu-Yong|Lee, Kang-Moon|Chung, Woo-Chul|Kim, Byung-Wook|Choi, Hwang|Cho, Se-Hyun|Kang, Hyong-Ju|Lee, Jin-Sun|Kim, Myung-Seok|Chae, Hiun-Suk|Chun, In-Sik
PMID: 16434865
Journal: Invest New Drugs. 2006 Sep;24(5):393-401.
Title: Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes.
Author: Zamboni, William C|Ramanathan, Ramesh K|McLeod, Howard L|Mani, Sridhar|Potter, Douglas M|Strychor, Sandra|Maruca, Lauren J|King, Cristi R|Jung, Laura L|Parise, Robert A|Egorin, Merrill J|Davis, Todd A|Marsh, Sharon
PMID: 16505951
Journal: Biol Pharm Bull. 2006 Mar;29(3):535-8.
Title: Comparison of synthetic DNA templates with authentic cDNA templates in terms of quantification by real-time quantitative reverse transcription polymerase chain reaction.
Author: Moriya, Yuka|Nakamura, Tsutomu|Okamura, Noboru|Sakaeda, Toshiyuki|Horinouchi, Masanori|Tamura, Takao|Aoyama, Nobuo|Kasuga, Masato|Okumura, Katsuhiko
PMID: 16508161
Journal: Cancer Res. 2006 May 1;66(9):4808-15.
Title: Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.
Author: Ludwig, Joseph A|Szakacs, Gergely|Martin, Scott E|Chu, Benjamin F|Cardarelli, Carol|Sauna, Zuben E|Caplen, Natasha J|Fales, Henry M|Ambudkar, Suresh V|Weinstein, John N|Gottesman, Michael M
PMID: 16651436
Journal: Clin Pharmacol Ther. 2006 May;79(5):449-60. Epub 2006 Apr 11.
Title: Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Author: Becquemont, Laurent|Glaeser, Hartmut|Drescher, Siegfried|Hitzl, Monika|Simon, Nicolas|Murdter, Thomas E|Heinkele, Georg|Hofmann, Ute|Schaefer, Christian|Burk, Oliver|Verstuyft, Celine|Eichelbaum, Michel|Fromm, Martin F
PMID: 16678547
Journal: Drug Metab Pharmacokinet. 2006 Apr;21(2):126-32.
Title: MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer.
Author: Komoto, Chiho|Nakamura, Tsutomu|Sakaeda, Toshiyuki|Kroetz, Deanna L|Yamada, Toshio|Omatsu, Hideaki|Koyama, Tatsuya|Okamura, Noboru|Miki, Ikuya|Tamura, Takao|Aoyama, Nobuo|Kasuga, Masato|Okumura, Katsuhiko
PMID: 16702732
Journal: Pharmacogenomics. 2006 Jun;7(4):575-85.
Title: Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8.
Author: Garcia-Martin, Elena|Pizarro, Rosa M|Martinez, Carmen|Gutierrez-Martin, Yolanda|Perez, Gabriela|Jover, Ramiro|Agundez, Jose Ag
PMID: 16753005
Journal: Planta Med. 2006 Jun;72(8):685-90. Epub 2006 Jun 1.
Title: Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
Author: Gutmann, Heike|Poller, Birk|Buter, Karin Berger|Pfrunder, Arabelle|Schaffner, Willi|Drewe, Jurgen
PMID: 16755466
Journal: Cancer Sci. 2006 Aug;97(8):774-9. Epub 2006 Jun 23.
Title: Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans.
Author: Bae, Sun-Young|Choi, Sun-Keun|Kim, Kyung-Rae|Park, Chang-Shin|Lee, Sung-Keun|Roh, Hyung-Keun|Shin, Dong-Woon|Pie, Jae-Eun|Woo, Ze-Hong|Kang, Ju-Hee
PMID: 16800822
Journal: Zhonghua Wai Ke Za Zhi. 2006 Jun 1;44(11):770-3.
Title: [The lethal effect of combined MDR1 antisense RNA with oxaliplatin and 5-FU on drug-resistant rectal carcinoma cells].
Author: Chen, Gang|Li, Shi-yong|Yu, Bo|An, Ping|Cai, Hui-yun
PMID: 16836929
Journal: In Vivo. 2006 Sep-Oct;20(5):637-43.
Title: Tumour-specific cytotoxicity and MDR-reversal activity of dihydropyridines.
Author: Engi, Helga|Sakagami, Hiroshi|Kawase, Masami|Parecha, Alpesh|Manvar, Dinesh|Kothari, Himanshu|Adlakha, Priti|Shah, Anamik|Motohashi, Noboru|Ocsovszki, Imre|Molnar, Joseph
PMID: 17091771
Journal: In Vivo. 2006 Sep-Oct;20(5):645-9.
Title: Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.
Author: Barath, Zoltan|Radics, Rita|Spengler, Gabriella|Ocsovszki, Imre|Kawase, Masami|Motohashi, Noboru|Shirataki, Yoshiaki|Shah, Anamik|Molnar, Jozsef
PMID: 17091772
Journal: Eur J Clin Pharmacol. 2007 Jan;63(1):9-16. Epub 2006 Dec 5.
Title: Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers.
Author: Osswald, Elena|Johne, Andreas|Laschinski, Gabriele|Arjomand-Nahad, Farhad|Malzahn, Uwe|Kirchheiner, Julia|Gerloff, Thomas|Meisel, Christian|Mrozikiewicz, Przemyslaw M|Chernov, Jury|Roots, Ivar|Kopke, Karla
PMID: 17146660
Journal: Phytother Res. 2007 Mar;21(3):239-44.
Title: Effects of herbal medicinal products and food supplements on induction of CYP1A2, CYP3A4 and MDR1 in the human colon carcinoma cell line LS180.
Author: Brandin, Helena|Viitanen, Eila|Myrberg, Olle|Arvidsson, Ann-Kristin
PMID: 17163579
Journal: Hum Psychopharmacol. 2007 Jan;22(1):49-53.
Title: Venlafaxine induces P-glycoprotein in human Caco-2 cells.
Author: Ehret, M J|Levin, G M|Narasimhan, M|Rathinavelu, A
PMID: 17191263
Journal: Mol Cancer Ther. 2007 Jan;6(1):236-43.
Title: Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression.
Author: Walther, Wolfgang|Arlt, Franziska|Fichtner, Iduna|Aumann, Jutta|Stein, Ulrike|Schlag, Peter M
PMID: 17237282
Journal: Inflamm Bowel Dis. 2007 Jun;13(6):710-20.
Title: Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.
Author: Blokzijl, Hans|Vander Borght, Sara|Bok, Lisette I H|Libbrecht, Louis|Geuken, Mariska|van den Heuvel, Fiona A J|Dijkstra, Gerard|Roskams, Tania A D|Moshage, Han|Jansen, Peter L M|Faber, Klaas Nico
PMID: 17262809
Journal: Eur J Clin Pharmacol. 2007 Jun;63(6):547-54. Epub 2007 Apr 3.
Title: Identification of NR1I2 genetic variation using resequencing.
Author: King, Cristi R|Xiao, Ming|Yu, Jinsheng|Minton, Matthew R|Addleman, Nicholas J|Van Booven, Derek J|Kwok, Pui-Yan|McLeod, Howard L|Marsh, Sharon
PMID: 17404718
Journal: Biol Pharm Bull. 2007 Jun;30(6):1144-6.
Title: Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor.
Author: Ohtsuki, Sumio|Kamoi, Mayu|Watanabe, Yuki|Suzuki, Hiroya|Hori, Satoko|Terasaki, Tetsuya
PMID: 17541169
Journal: Mol Cancer Res. 2007 Jun;5(6):641-53.
Title: Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines.
Author: Gomez-Martinez, Angeles|Garcia-Morales, Pilar|Carrato, Alfredo|Castro-Galache, Maria D|Soto, Jose L|Carrasco-Garcia, Estefania|Garcia-Bautista, Miriam|Guaraz, Patricia|Ferragut, Jose A|Saceda, Miguel
PMID: 17579122
Journal: Mol Cancer Ther. 2007 Jul;6(7):2092-102.
Title: Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Author: Katayama, Kazuhiro|Yoshioka, Sho|Tsukahara, Satomi|Mitsuhashi, Junko|Sugimoto, Yoshikazu
PMID: 17620438
Journal: Int J Oncol. 2007 Sep;31(3):633-41.
Title: The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
Author: Fedier, Andre|Dedes, Konstantin J|Imesch, Patrick|Von Bueren, Andre O|Fink, Daniel
PMID: 17671692
Journal: Assay Drug Dev Technol. 2007 Aug;5(4):541-50.
Title: Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors.
Author: Schwab, Richard|Micsik, Tamas|Szokoloczi, Orsolya|Schafer, Eszter|Tihanyi, Balazs|Tihanyi, Tibor|Kupcsulik, Peter|Diofalvi, Katalin|Mersich, Tamas|Besznyak, Istvan Jr|Zarand, Attila|Mihalik, Rudolf|Sarkadi, Balazs|Keri, Gyorgy|Pap, Akos|Jakab, Ferenc|Kopp
PMID: 17767422
Journal: Mol Cancer Ther. 2007 Nov;6(11):2985-94.
Title: Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.
Author: Emdad, Luni|Lebedeva, Irina V|Su, Zao-Zhong|Sarkar, Devanand|Dent, Paul|Curiel, David T|Fisher, Paul B
PMID: 18025283
Journal: Pharmacogenomics J. 2008 Aug;8(4):289-96. Epub 2007 Jun 12.
Title: ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
Author: Aird, R E|Thomson, M|Macpherson, J S|Thurston, D E|Jodrell, D I|Guichard, S M
PMID: 17563765
Journal: J Cancer Res Clin Oncol. 2008 Mar;134(3):317-22. Epub 2007 Aug 3.
Title: No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients.
Author: Petrova, Darinka Todorova|Nedeva, Petya|Maslyankov, Svilen|Toshev, Svetoslav|Yaramov, Nikolay|Atanasova, Srebrena|Toncheva, Draga|Oellerich, Michael|von Ahsen, Nicolas
PMID: 17674045
Journal: BMC Cancer. 2008 Feb 12;8:50.
Title: ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: a preliminary study.
Author: Huang, Ming-Yii|Fang, Wei-Yu|Lee, Su-Chen|Cheng, Tian-Lu|Wang, Jaw-Yuan|Lin, Shiu-Ru
PMID: 18267032
Journal: Exp Mol Med. 2008 Feb 29;40(1):109-17.
Title: Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability.
Author: Lee, Wan|Choi, Hyo Im|Kim, Mi Jin|Park, Seung Yoon
PMID: 18305404
Journal: Drug Metab Dispos. 2008 Jul;36(7):1283-90.
Title: Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro.
Author: Zhang, Wenxia|Lim, Lee-Yong
PMID: 18385293
Journal: J Clin Oncol. 2008 Jun 1;26(16):2690-8.
Title: Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
Author: Braun, Michael S|Richman, Susan D|Quirke, Philip|Daly, Catherine|Adlard, Julian W|Elliott, Faye|Barrett, Jennifer H|Selby, Peter|Meade, Angela M|Stephens, Richard J|Parmar, Mahesh K B|Seymour, Matthew T
PMID: 18509181
Journal: Int J Clin Pharmacol Ther. 2008 May;46(5):226-35.
Title: Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines.
Author: Diaz-Carballo, D|Freista Hler, M|Malak, S|Bardenheuer, W|Reusch, H P
PMID: 18538108
Journal: Life Sci. 2008 Aug 15;83(7-8):301-4.
Title: MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese.
Author: Sugimoto, Mitsushige|Furuta, Takahisa|Shirai, Naohito|Kodaira, Chise|Nishino, Masafumi|Yamade, Mihoko|Ikuma, Mutsuhiro|Sugimura, Haruhiko|Ishizaki, Takashi|Hishida, Akira
PMID: 18644389
Journal: BMC Gastroenterol. 2008 Aug 1;8:33.
Title: Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy.
Author: Lee, Tae-Bum|Park, Jung-Hee|Min, Young-Don|Kim, Kyung-Jong|Choi, Cheol-Hee
PMID: 18673531
Journal: J Nucl Med. 2008 Sep;49(9):1480-8.
Title: Combination therapy and noninvasive imaging with a dual therapeutic vector expressing MDR1 short hairpin RNA and a sodium iodide symporter.
Author: Park, Seung-Yoon|Kwak, Wonjung|Thapa, Narendra|Jung, Mi-Yeon|Nam, Ju-Ock|So, In-Seop|Kim, So-Youn|Yoo, Jeongsoo|Lee, Jaetae|Kim, In-San
PMID: 18703598
Journal: Oncol Rep. 2008 Dec;20(6):1433-9.
Title: Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells.
Author: Xia, Zhongsheng|Zhu, Zhaohua|Zhang, Liyong|Royal, Crista|Liu, Zhongmin|Chen, Qikui|Adam, Bao-Ling
PMID: 19020725
Journal: Anticancer Res. 2008 Nov-Dec;28(6B):3921-8.
Title: ABCB1 gene polymorphisms and expression of P-glycoprotein and long-term prognosis in colorectal cancer.
Author: De Iudicibus, Sara|De Pellegrin, Alessandro|Stocco, Gabriele|Bartoli, Fiora|Bussani, Rossana|Decorti, Giuliana
PMID: 19192650
Journal: BMC Med Genet. 2009 Feb 27;10:18.
Title: The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study.
Author: Andersen, Vibeke|Agerstjerne, Lene|Jensen, Dorte|Ostergaard, Mette|Saebo, Mona|Hamfjord, Julian|Kure, Elin|Vogel, Ulla
PMID: 19250544
Journal: Int J Oncol. 2009 May;34(5):1281-9.
Title: Identification of proteins associated to multi-drug resistance in LoVo human colon cancer cells.
Author: Visentin, Michele|Simula, Maria Paola|Sartor, Franca|Petrucco, Alessandra|De Re, Valli|Toffoli, Giuseppe
PMID: 19360340
Journal: Cancer Genet Cytogenet. 2009 Apr 15;190(2):81-7.
Title: Adrenaline induces chemoresistance in HT-29 colon adenocarcinoma cells.
Author: Yao, Herui|Duan, Zhaohui|Wang, Minghui|Awonuga, Awoniyi O|Rappolee, Daniel|Xie, Yufen
PMID: 19380024
Journal: Int J Colorectal Dis. 2009 Aug;24(8):895-905.
Title: ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer.
Author: Panczyk, Mariusz|Balcerczak, Ewa|Piaskowski, Sylwester|Jamroziak, Krzysztof|Pasz-Walczak, Grazyna|Mirowski, Marek
PMID: 19415305
Journal: Eur J Pharm Sci. 2009 Jun 28;37(3-4):463-8.
Title: Expression and activity of the efflux transporters ABCB1, ABCC2 and ABCG2 in the human colorectal carcinoma cell line LS513.
Author: Salphati, Laurent|Plise, Emile G|Li, Guangmin
PMID: 19491037
Journal: J Control Release. 2009 Dec 16;140(3):277-83.
Title: Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel.
Author: Liu, Changxing|Zhao, Gang|Liu, Jian|Ma, Nianchun|Chivukula, Padmanabh|Perelman, Loren|Okada, Keisaku|Chen, Zongyou|Gough, David|Yu, Lei
PMID: 19699770
Journal: Ai Zheng. 2009 Sep;28(9):932-8.
Title: [Correlation of chemosensitivity tested using histoculture drug response assay to expression of multidrug resistance genes and proteins in colorectal cancer tissues].
Author: Yuan, Shu-Qiang|Zhou, Zhi-Wei|Liang, Yong-Ju|Fu, Li-Wu|Chen, Gong|Qiu, Hai-Bo|Zhang, Li-Yi
PMID: 19728910
Journal: BMC Cancer. 2009 Nov 21;9:407.
Title: Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.
Author: Andersen, Vibeke|Ostergaard, Mette|Christensen, Jane|Overvad, Kim|Tjonneland, Anne|Vogel, Ulla
PMID: 19930591
Journal: Mol Med Rep. 2009 Jul-Aug;2(4):579-84.
Title: Stable reversal of multidrug resistance in colon cancer cells by RNA interference targeting the MDR1 gene.
Author: Xia, Zhongsheng|Zhang, Liyong|Chen, Qikui|Royal, Crista|Yu, Zhong|Liu, Zhongmin|Adam, Bao-Ling
PMID: 21475869
Journal: Med Oncol. 2010 Dec;27(4):1066-72.
Title: MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer.
Author: Paule, Bernard|Castagne, Vincent|Picard, Veronique|Saffroy, Raphael|Adam, Rene|Guettier, Catherine|Farinotti, Robert|Bonhomme-Faivre, Laurence
PMID: 19862647
Journal: J Exp Clin Cancer Res. 2010 Jan 4;29:1.
Title: Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice.
Author: Zhao, ZhenZhen|Liu, Wei|Su, Yuxi|Zhu, Jin|Zheng, GaiHuan|Luo, Qing|Jin, XianQing
PMID: 20044941
Journal: Biol Pharm Bull. 2010;33(2):255-9.
Title: Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells.
Author: Okura, Takashi|Ibe, Michiko|Umegaki, Keizo|Shinozuka, Kazumasa|Yamada, Shizuo
PMID: 20118549
Journal: Anticancer Drugs. 2010 Jun;21(5):523-31.
Title: Reduced drug accumulation is more important in acquired resistance against oxaliplatin than against cisplatin in isogenic colon cancer cells.
Author: Ekblad, Lars|Kjellstrom, Johan|Johnsson, Anders
PMID: 20168208
Journal: Carcinogenesis. 2010 Jun;31(6):1003-9.
Title: Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Author: Ku, Ja-Lok|Shin, Young-Kyoung|Kim, Duck-Woo|Kim, Kyung-Hee|Choi, Jin-Sung|Hong, Sung-Hye|Jeon, You-Kyung|Kim, Sung-Hee|Kim, Hong-Sun|Park, Jae-Hyun|Kim, Il-Jin|Park, Jae-Gahb
PMID: 20176655
Journal: Cancer Gene Ther. 2010 Jul;17(7):492-500.
Title: Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model.
Author: Ahn, S J|Jeon, Y H|Lee, Y J|Lee, Y L|Lee, S-W|Ahn, B-C|Ha, J-H|Lee, J
PMID: 20186172
Journal: J Cancer Res Clin Oncol. 2010 Nov;136(11):1697-707.
Title: Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells.
Author: Ding, Zhenyu|Yang, Li|Xie, Xiaodong|Xie, Fangwei|Pan, Feng|Li, Jianjun|He, Jianming|Liang, Houjie
PMID: 20217131
Journal: Biochem Pharmacol. 2010 Jul 1;80(1):72-9.
Title: Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.
Author: Patwardhan, Gauri|Gupta, Vineet|Huang, Juowen|Gu, Xin|Liu, Yong-Yu
PMID: 20298675
Journal: Mol Cancer Ther. 2010 May;9(5):1308-17.
Title: Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Author: Serova, Maria|Astorgues-Xerri, Lucile|Bieche, Ivan|Albert, Sebastien|Vidaud, Michel|Benhadji, Karim A|Emami, Shahin|Vidaud, Dominique|Hammel, Pascal|Theou-Anton, Nathalie|Gespach, Christian|Faivre, Sandrine|Raymond, Eric
PMID: 20406951
Journal: Int J Colorectal Dis. 2010 Oct;25(10):1167-76.
Title: ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer.
Author: Balcerczak, Ewa|Panczyk, Mariusz|Piaskowski, Sylwester|Pasz-Walczak, Grazyna|Salagacka, Aleksandra|Mirowski, Marek
PMID: 20533057
Journal: Mol Cancer. 2010 Jun 11;9:145.
Title: Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.
Author: Liu, Yong-Yu|Gupta, Vineet|Patwardhan, Gauri A|Bhinge, Kaustubh|Zhao, Yunfeng|Bao, Jianxiong|Mehendale, Harihara|Cabot, Myles C|Li, Yu-Teh|Jazwinski, S Michal
PMID: 20540746
Journal: Anticancer Res. 2010 Jun;30(6):2041-8.
Title: Inhibition of Wnt signaling pathway decreases chemotherapy-resistant side-population colon cancer cells.
Author: Chikazawa, Nobuhito|Tanaka, Haruo|Tasaka, Takehiko|Nakamura, Masafumi|Tanaka, Masao|Onishi, Hideya|Katano, Mitsuo
PMID: 20651349
Journal: Cancer Res. 2010 Sep 1;70(17):6767-78.
Title: CDX2 regulates multidrug resistance 1 gene expression in malignant intestinal epithelium.
Author: Takakura, Yuji|Hinoi, Takao|Oue, Naohide|Sasada, Tatsunari|Kawaguchi, Yasuo|Okajima, Masazumi|Akyol, Aytekin|Fearon, Eric R|Yasui, Wataru|Ohdan, Hideki
PMID: 20699370
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010 Jul;30(7):743-7.
Title: [Effects of changwelqing on nuclear translocation of Y-box binding protein-1 and expression of P-glycoprotein in human colon cancer cell line with drug-resistance induced by vincristine].
Author: Xu, Jian-hua|Deng, Wan-li|Fan, Zhong-ze
PMID: 20929136
Journal: Mol Imaging. 2010 Dec;9(6):343-50.
Title: Evaluation of the reversal of multidrug resistance by MDR1 ribonucleic acid interference in a human colon cancer model using a Renilla luciferase reporter gene and coelenterazine.
Author: Jeon, Yong Hyun|Bae, Seon-ae|Lee, Yong Jin|Lee, You La|Lee, Sang-Woo|Yoon, Ghil-Suk|Ahn, Byeong-Cheol|Ha, Jeoung-Hee|Lee, Jaetae
PMID: 21084030
Journal: Pharmacogenomics. 2010 Dec;11(12):1715-23.
Title: ABCB1 gene polymorphisms are associated with adverse reactions in fluoropyrimidine-treated colorectal cancer patients.
Author: Gonzalez-Haba, Eva|Garcia, Maria I|Cortejoso, Lucia|Lopez-Lillo, Carolina|Barrueco, Nelida|Garcia-Alfonso, Pilar|Alvarez, Sonsoles|Jimenez, Jose L|Martin, Maria L|Munoz-Fernandez, Maria A|Sanjurjo, Maria|Lopez-Fernandez, Luis A
PMID: 21142915
Journal: Mol Biol Rep. 2011 Jun;38(5):2939-43.
Title: Association of the colorectal cancer and MDR1 gene polymorphism in an Iranian population.
Author: Khedri, Azam|Nejat-Shokouhi, Amireh|Salek, Roham|Esmaeili, Habibollah|Mokhtarifar, Ali|Entezari Heravi, Reza|Tatari, Farnoosh|Behravan, Javad|Miladpour, Behnoosh|Omidvar Tehrani, Shahireh
PMID: 20127181
Journal: Pharmacogenomics J. 2011 Feb;11(1):61-71.
Title: Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer.
Author: Glimelius, B|Garmo, H|Berglund, A|Fredriksson, L A|Berglund, M|Kohnke, H|Bystrom, P|Sorbye, H|Wadelius, M
PMID: 20177420
Journal: Pharmacogenomics J. 2011 Jun;11(3):214-26.
Title: Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
Author: Cecchin, E|Agostini, M|Pucciarelli, S|De Paoli, A|Canzonieri, V|Sigon, R|De Mattia, E|Friso, M L|Biason, P|Visentin, M|Nitti, D|Toffoli, G
PMID: 20368715
Journal: Carcinogenesis. 2011 May;32(5):667-75.
Title: COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer.
Author: Sui, Hua|Zhou, Shoufeng|Wang, Yan|Liu, Xuan|Zhou, Lihong|Yin, Peihao|Fan, Zhongze|Li, Qi
PMID: 21296766
Journal: Endocr Relat Cancer. 2011 Mar 9;18(2):265-76.
Title: Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk.
Author: Sainz, J|Rudolph, A|Hein, R|Hoffmeister, M|Buch, S|von Schonfels, W|Hampe, J|Schafmayer, C|Volzke, H|Frank, B|Brenner, H|Forsti, A|Hemminki, K|Chang-Claude, J
PMID: 21317201
Journal: Gastroenterology. 2011 Jul;141(1):269-78.
Title: Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.
Author: Emmink, Benjamin L|Van Houdt, Winan J|Vries, Robert G|Hoogwater, Frederik J H|Govaert, Klaas M|Verheem, Andre|Nijkamp, Maarten W|Steller, Ernst J A|Jimenez, Connie R|Clevers, Hans|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 21459094
Journal: Endocr Relat Cancer. 2011 Jun 8;18(3):371-84.
Title: Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes.
Author: Rudolph, Anja|Sainz, Juan|Hein, Rebecca|Hoffmeister, Michael|Frank, Bernd|Forsti, Asta|Brenner, Hermann|Hemminki, Kari|Chang-Claude, Jenny
PMID: 21490239
Journal: Mol Cancer Ther. 2011 Jul;10(7):1252-63.
Title: Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo.
Author: Yamazaki, Ryuta|Nishiyama, Yukiko|Furuta, Tomio|Hatano, Hiroshi|Igarashi, Yoshiaki|Asakawa, Naoyuki|Kodaira, Hiroshi|Takahashi, Hiroyuki|Aiyama, Ritsuo|Matsuzaki, Takeshi|Yagi, Nao|Sugimoto, Yoshikazu
PMID: 21566063
Journal: Mol Cancer Ther. 2011 Aug;10(8):1490-9.
Title: Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.
Author: Sooryakumar, Dhriti|Dexheimer, Thomas S|Teicher, Beverly A|Pommier, Yves
PMID: 21636699
Journal: Mol Cancer. 2011 Jul 6;10:80.
Title: Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells.
Author: Basseville, Agnes|Preisser, Laurence|de Carne Trecesson, Sophie|Boisdron-Celle, Michele|Gamelin, Erick|Coqueret, Olivier|Morel, Alain
PMID: 21733184
Journal: Biomed Pharmacother. 2011 Aug;65(5):345-53.
Title: The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines.
Author: Podolski-Renic, Ana|Andelkovic, Tijana|Bankovic, Jasna|Tanic, Nikola|Ruzdijic, Sabera|Pesic, Milica
PMID: 21775090
Journal: Am J Physiol Cell Physiol. 2011 Nov;301(5):C984-94.
Title: The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein.
Author: Goncalves, Pedro|Gregorio, Ines|Martel, Fatima
PMID: 21775706
Journal: Clin Cancer Res. 2011 Sep 15;17(18):6029-39.
Title: Prognostic impact of DeltaTAp73 isoform levels and their target genes in colon cancer patients.
Author: Soldevilla, Beatriz|Diaz, Raquel|Silva, Javier|Campos-Martin, Yolanda|Munoz, Concepcion|Garcia, Vanesa|Garcia, Jose M|Pena, Cristina|Herrera, Mercedes|Rodriguez, Marta|Gomez, Irene|Mohamed, Nagat|Marques, Margarita M|Bonilla, Felix|Dominguez, Gemma
PMID: 21807636
Journal: J Am Coll Nutr. 2011 Aug;30(4):265-73.
Title: Long-chain polyunsaturated fatty acids promote paclitaxel cytotoxicity via inhibition of the MDR1 gene in the human colon cancer Caco-2 cell line.
Author: Kuan, Cheng-Yi|Walker, Terry H|Luo, Pengju G|Chen, Chin-Fu
PMID: 21917707
Journal: Eur J Pharmacol. 2011 Nov 16;670(1):74-84.
Title: MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment.
Author: Azzariti, Amalia|Quatrale, Anna E|Porcelli, Letizia|Colabufo, Nicola A|Cantore, Mariangela|Cassano, Giuseppe|Gasparre, Giuseppe|Iannelli, Giuseppina|Tommasi, Stefania|Panaro, Maria A|Paradiso, Angelo
PMID: 21925160
Journal: PLoS Comput Biol. 2011 Sep;7(9):e1002143.
Title: A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery.
Author: Ballesta, Annabelle|Dulong, Sandrine|Abbara, Chadi|Cohen, Boris|Okyar, Alper|Clairambault, Jean|Levi, Francis
PMID: 21931543
Journal: Stem Cells. 2011 Nov;29(11):1661-71.
Title: MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells.
Author: Bitarte, Nerea|Bandres, Eva|Boni, Valentina|Zarate, Ruth|Rodriguez, Javier|Gonzalez-Huarriz, Marisol|Lopez, Ines|Javier Sola, Jesus|Alonso, Marta M|Fortes, Puri|Garcia-Foncillas, Jesus
PMID: 21948564
Journal: Anticancer Res. 2011 Oct;31(10):3285-8.
Title: Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.
Author: Spengler, Gabriella|Handzlik, Jadwiga|Ocsovszki, Imre|Viveiros, Miguel|Kiec-Kononowicz, Katarzyna|Molnar, Joseph|Amaral, Leonard
PMID: 21965738
Journal: Asian Pac J Cancer Prev. 2011;12(11):3141-5.
Title: MDR1 gene polymorphisms: possible association with its expression and clinicopathology characteristics in colorectal cancer patients.
Author: Samanian, Sara|Mahjoubi, Frouzandeh|Mahjoubi, Bahar|Mirzaee, Rezvan|Azizi, Rasool
PMID: 22394004
Journal: Mol Cancer Ther. 2012 Mar;11(3):700-9.
Title: TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity in multiple dosing regimens.
Author: Hikichi, Yuichi|Honda, Kohei|Hikami, Kouki|Miyashita, Hitoshi|Kaieda, Isao|Murai, Saomi|Uchiyama, Noriko|Hasegawa, Maki|Kawamoto, Tomohiro|Sato, Takashi|Ichikawa, Takashi|Cao, Sheldon|Nie, Zhe|Zhang, Lilly|Yang, Johnny|Kuida, Keisuke|Kupperman, Erik
PMID: 22188812
Journal: J Cancer Res Clin Oncol. 2012 Jun;138(6):979-89.
Title: MDR1 gene C3435T polymorphism and cancer risk: a meta-analysis of 34 case-control studies.
Author: Wang, Jun|Wang, Baocheng|Bi, Jingwang|Li, Kainan|Di, Jianshi
PMID: 22358302
Journal: PLoS One. 2012;7(3):e32784.
Title: A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer.
Author: Campa, Daniele|Sainz, Juan|Pardini, Barbara|Vodickova, Ludmila|Naccarati, Alessio|Rudolph, Anja|Novotny, Jan|Forsti, Asta|Buch, Stephan|von Schonfels, Witigo|Schafmayer, Clemens|Volzke, Henry|Hoffmeister, Michael|Frank, Bernd|Barale, Roberto|Hemminki, Kar
PMID: 22396794
Journal: Phytomedicine. 2012 May 15;19(7):625-30.
Title: Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.
Author: Lai, Kuang-Chi|Kuo, Chao-Lin|Ho, Heng-Chien|Yang, Jai-Sing|Ma, Chia-Yu|Lu, Hsu-Feng|Huang, Hui-Ying|Chueh, Fu-Shin|Yu, Chien-Chih|Chung, Jing-Gung
PMID: 22397993
Journal: J Exp Clin Cancer Res. 2012 Mar 16;31:23.
Title: GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells.
Author: Song, Min|Zang, Weidong|Zhang, Baohua|Cao, Jing|Yang, Guanrui
PMID: 22424291
Journal: Br J Cancer. 2012 Apr 10;106(8):1395-405.
Title: Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells.
Author: Stein, U|Fleuter, C|Siegel, F|Smith, J|Kopacek, A|Scudiero, D A|Hite, K M|Schlag, P M|Shoemaker, R H|Walther, W
PMID: 22460269
Journal: Int J Clin Exp Med. 2012;5(2):186-94. Epub 2012 Apr 6.
Title: ERCC1 C118T associates with response to FOLFOX4 chemotherapy in colorectal cancer patients in Han Chinese.
Author: Chai, Haina|Pan, Jie|Zhang, Xuelin|Zhang, Xiaoyan|Shen, Xiaoying|Li, Hang|Zhang, Kehao|Yang, Changqing|Sheng, Haihui|Gao, Hengjun
PMID: 22567180
Journal: Hepatogastroenterology. 2012 Jun;59(116):1075-8.
Title: Can immunohistochemistry of multidrug-resistant proteins replace the histoculture drug response assay in colorectal adenocarcinomas?
Author: Lee, Ju-Han|Um, Jun-Won|Lee, Ji-Hye|Kim, Seo-Hee|Lee, Eung-Seok|Kim, Young-Sik
PMID: 22580657
Journal: BMC Mol Biol. 2012 Jul 30;13:25.
Title: Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell lines.
Author: Balaguer, Trinidad Mata|Gomez-Martinez, Angeles|Garcia-Morales, Pilar|Lacueva, Javier|Calpena, Rafael|Reverte, Lourdes Rocamora|Riquelme, Natividad Lopez|Martinez-Lacaci, Isabel|Ferragut, Jose A|Saceda, Miguel
PMID: 22846052
Journal: PLoS One. 2012;7(8):e41763.
Title: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer.
Author: Zhu, Ming Ming|Tong, Jin Lu|Xu, Qi|Nie, Fang|Xu, Xi Tao|Xiao, Shu Dong|Ran, Zhi Hua
PMID: 22870247
Journal: J Prev Med Public Health. 2012 Jul;45(4):251-8.
Title: Quantitative analysis of cancer-associated gene methylation connected to risk factors in Korean colorectal cancer patients.
Author: Kang, Ho-Jin|Kim, Eun-Jeong|Kim, Byoung-Gwon|You, Chang-Hun|Lee, Sang-Yong|Kim, Dong-Il|Hong, Young-Seoub
PMID: 22880157
Journal: Pharmacogenomics. 2012 Jul;13(10):1173-91.
Title: Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients.
Author: Cortejoso, Lucia|Lopez-Fernandez, Luis A
PMID: 22909207
Journal: PLoS One. 2012;7(10):e48189.
Title: Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues.
Author: Gromnicova, Radka|Romero, Ignacio|Male, David
PMID: 23133566
Journal: Toxicol Mech Methods. 2013 May;23(4):235-9.
Title: Associations between the functional polymorphisms in the ABCB1 transporter gene and colorectal cancer risk: a case-control study in Turkish population.
Author: Ozhan, Gul|Kara, Mehtap|Sari, Fatih M|Yanar, Hakan T|Ercan, Gulcin|Alpertunga, Buket
PMID: 23193993
Journal: Aliment Pharmacol Ther. 2013 Feb;37(4):383-91.
Title: Systematic review: diet-gene interactions and the risk of colorectal cancer.
Author: Andersen, V|Holst, R|Vogel, U
PMID: 23216531
Journal: Colorectal Dis. 2013 Jan;15(1):12-8.
Title: ABCB1/MDR1 gene polymorphism and colorectal cancer risk: a meta-analysis of case-control studies.
Author: He, T|Mo, A|Zhang, K|Liu, L
PMID: 23279665
Journal: Clin Colorectal Cancer. 2013 Jun;12(2):122-7.
Title: Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer.
Author: Arienti, Chiara|Tesei, Anna|Verdecchia, Giorgio Maria|Framarini, Massimo|Virzi, Salvatore|Grassi, Antonio|Scarpi, Emanuela|Turci, Livia|Silvestrini, Rosella|Amadori, Dino|Zoli, Wainer
PMID: 23332421
Journal: Mol Nutr Food Res. 2013 Sep;57(9):1638-48.
Title: The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis.
Author: Noratto, Giuliana D|Jutooru, Indira|Safe, Stephen|Angel-Morales, Gabriela|Mertens-Talcott, Susanne U
PMID: 23471840
Journal: Tumour Biol. 2013 Jun;34(3):1949-57.
Title: Association between the C3435T polymorphism of ABCB1/MDR1 gene (rs1045642) and colorectal cancer susceptibility : a meta-analysis based on 11,339 subjects.
Author: Zhao, Li|Li, Kai|Li, Wusheng|Yang, Zhen
PMID: 23504525
Journal: Cancer Chemother Pharmacol. 2013 Jun;71(6):1463-72.
Title: Differential toxicity biomarkers for irinotecan- and oxaliplatin-containing chemotherapy in colorectal cancer.
Author: Cortejoso, Lucia|Garcia, Maria I|Garcia-Alfonso, Pilar|Gonzalez-Haba, Eva|Escolar, Fernando|Sanjurjo, Maria|Lopez-Fernandez, Luis A
PMID: 23543295
Journal: Curr Drug Targets. 2013 Jun;14(7):777-97.
Title: Therapeutic targeting of CPT-11 induced diarrhea: a case for prophylaxis.
Author: Swami, Umang|Goel, Sanjay|Mani, Sridhar
PMID: 23597015
Journal: Asian Pac J Trop Med. 2013 May 13;6(5):407-9.
Title: Effect of ionizing radiation on transcription of colorectal cancer MDR1 gene of HCT-8 cells.
Author: Li, Xiao-Feng|Ma, Lin|Lu, Jing|Kong, Li-Xia|Long, Xiao-Hua|Liao, Su-Huan|Chi, Bao-Rong
PMID: 23608383
Journal: Pharmacogenomics. 2013 Jun;14(8):897-911.
Title: Association of ABCB1 genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis.
Author: Wu, Huizhe|Kang, Hui|Liu, Yong|Xiao, Qinghuan|Zhang, Yining|Sun, Mingjun|Liu, Duo|Wang, Zhe|Zhao, Haishan|Yao, Weifan|Jia, Tianhong|Wang, Enhua|Zheng, Zhihong|Wei, Minjie
PMID: 23746184
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jun;16(6):524-8.
Title: [Correlation of MDR1 and ABCG2 genetic polymorphisms with the efficacy and adverse events of irinotecan chemotherapy in patients with colorectal cancer].
Author: Sun, Zhi-wei|Wang, Xi-cheng|Gao, Jing|Li, Jie|Li, Yan-yan|Dang, Yun-zhi|Shen, Lin
PMID: 23801203
Journal: Asian Pac J Cancer Prev. 2013;14(5):3085-91.
Title: Associations of ABCB1 and XPC genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis in a Chinese population.
Author: Yue, Ai-Min|Xie, Zhen-Bin|Zhao, Hong-Feng|Guo, Shu-Ping|Shen, Yu-Hou|Wang, Hai-Pu
PMID: 23803084
Journal: Biochem Biophys Res Commun. 2013 Aug 30;438(3):513-8.
Title: JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells.
Author: Nishimoto, Arata|Kugimiya, Naruji|Hosoyama, Toru|Enoki, Tadahiko|Li, Tao-Sheng|Hamano, Kimikazu
PMID: 23911788
Journal: Cancer Chemother Pharmacol. 2013 Sep;72(3):683-97.
Title: Molecular and cytogenetic changes in multi-drug resistant cancer cells and their influence on new compounds testing.
Author: Podolski-Renic, Ana|Jadranin, Milka|Stankovic, Tijana|Bankovic, Jasna|Stojkovic, Sonja|Chiourea, Maria|Aljancic, Ivana|Vajs, Vlatka|Tesevic, Vele|Ruzdijic, Sabera|Gagos, Sarantis|Tanic, Nikola|Pesic, Milica
PMID: 23934261
Journal: Eur J Cancer. 2013 Nov;49(16):3507-16.
Title: A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).
Author: Middleton, Gary|Brown, Sarah|Lowe, Catherine|Maughan, Timothy|Gwyther, Stephen|Oliver, Alfred|Richman, Susan|Blake, Denise|Napp, Vicky|Marshall, Helen|Wadsley, Jonathan|Maisey, Nick|Chau, Ian|Hill, Mark|Gollins, Simon|Myint, Sun|Slater, Sarah|Wagstaff, Jo
PMID: 23953030
Journal: PLoS One. 2013 Aug 19;8(8):e72119.
Title: Low ABCB1 gene expression is an early event in colorectal carcinogenesis.
Author: Andersen, Vibeke|Vogel, Ulla|Godiksen, Sine|Frenzel, Franz B|Saebo, Mona|Hamfjord, Julian|Kure, Elin|Vogel, Lotte K
PMID: 23977225
Journal: Phytomedicine. 2013 Dec 15;21(1):47-61.
Title: Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells.
Author: Eid, Safaa Yehia|El-Readi, Mahmoud Zaki|Eldin, Essam Eldin Mohamed Nour|Fatani, Sameer Hassan|Wink, Michael
PMID: 23999162
Journal: Biomed Pharmacother. 2013 Oct;67(8):791-9.
Title: Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer.
Author: Liu, Yi-Shiuan|Hsu, Hung-Chih|Tseng, Kai-Chi|Chen, Hua-Chien|Chen, Shu-Jen
PMID: 24138824
Journal: ScientificWorldJournal. 2013 Nov 7;2013:716289.
Title: Characterization of human colorectal cancer MDR1/P-gp Fab antibody.
Author: Zhang, Xuemei|Xiao, Gary Guishan|Gao, Ying
PMID: 24348182
Journal: Pak J Med Sci. 2013 Sep;29(5):1269-74.
Title: Meta-Analysis of ABCB1 3435C>T Polymorphism and Colorectal Cancer.
Author: Zhang, Dan|Wang, Cun|Zhou, Zongguang
PMID: 24353734
Journal: Chin J Integr Med. 2014 Aug;20(8):610-7.
Title: Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug resistance through COX-2 pathway in colorectal cancer.
Author: Sui, Hua|Zhu, Hui-rong|Wu, Jie|Nikitin, Alexander Yu|Cai, Jian-feng|Fan, Zhong-ze|Li, Qi
PMID: 23543356
Journal: Oncogene. 2014 Jul 10;33(28):3717-29.
Title: miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cells.
Author: Takwi, A A|Wang, Y-M|Wu, J|Michaelis, M|Cinatl, J|Chen, T
PMID: 23934188
Journal: Mol Med Rep. 2014 Jan;9(1):261-6.
Title: Pien Tze Huang suppresses the stem-like side population in colorectal cancer cells.
Author: Wei, Lihui|Chen, Pangyu|Chen, Youqin|Shen, Aling|Chen, Hongwei|Lin, Wei|Hong, Zhenfeng|Sferra, Thomas J|Peng, Jun
PMID: 24173665
Journal: Int J Cancer. 2014 Jun 1;134(11):2656-62.
Title: Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer.
Author: Melson, Joshua|Li, Yan|Cassinotti, Elisa|Melnikov, Anatoliy|Boni, Luigi|Ai, Junmei|Greenspan, Michael|Mobarhan, Sohrab|Levenson, Victor|Deng, Youping
PMID: 24288256
Journal: J Med Chem. 2014 Feb 27;57(4):1289-98.
Title: Optimization of the lactam side chain of 7-azaindenoisoquinoline topoisomerase I inhibitors and mechanism of action studies in cancer cells.
Author: Kiselev, Evgeny|Sooryakumar, Dhriti|Agama, Keli|Cushman, Mark|Pommier, Yves
PMID: 24502276
Journal: Cell Biosci. 2014 Apr 1;4(1):17.
Title: Tissue-specific regulation of pregnane X receptor in cancer development and therapy.
Author: Robbins, Delira|Chen, Taosheng
PMID: 24690092
Journal: Adv Pharm Bull. 2014;4(3):219-24.
Title: Reduced ABCB1 Expression and Activity in the Presence of Acrylic Copolymers.
Author: Mohammadzadeh, Ramin|Baradaran, Behzad|Valizadeh, Hadi|Yousefi, Bahman|Zakeri-Milani, Parvin
PMID: 24754004
Journal: Anticancer Drugs. 2014 Sep;25(8):908-16.
Title: TCF4 silencing sensitizes the colon cancer cell line to oxaliplatin as a common chemotherapeutic drug.
Author: Gheidari, Fatemeh|Bakhshandeh, Behnaz|Teimoori-Toolabi, Ladan|Mehrtash, Amirhosein|Ghadir, Mahdis|Zeinali, Sirous
PMID: 24869759
Journal: PLoS One. 2014 Jun 5;9(6):e98882.
Title: HIF-1alpha inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-glycoprotein.
Author: Chen, Jianfang|Ding, Zhenyu|Peng, Yonghai|Pan, Feng|Li, Jianjun|Zou, Lan|Zhang, Yanling|Liang, Houjie
PMID: 24901645
Journal: PLoS One. 2014 Jun 5;9(6):e98560.
Title: Sinomenine sensitizes multidrug-resistant colon cancer cells (Caco-2) to doxorubicin by downregulation of MDR-1 expression.
Author: Liu, Zhen|Duan, Zhi-Jun|Chang, Jiu-Yang|Zhang, Zhi-Feng|Chu, Rui|Li, Yu-Ling|Dai, Ke-Hang|Mo, Guang-Quan|Chang, Qing-Yong
PMID: 24901713
Journal: Int J Oncol. 2014 Sep;45(3):1175-83.
Title: Characterization of side population cells isolated from the colon cancer cell line SW480.
Author: Xiong, Binghong|Ma, Li|Hu, Xiang|Zhang, Caiquan|Cheng, Yong
PMID: 24926880
Journal: Invest New Drugs. 2014 Oct;32(5):893-903.
Title: Resistance mechanisms of cancer cells to the novel vacuolar H(+)-ATPase inhibitor archazolid B.
Author: Hamm, Rebecca|Sugimoto, Yoshikazu|Steinmetz, Heinrich|Efferth, Thomas
PMID: 25065443
Journal: Farm Hosp. 2014 Jul 1;38(4):283-90.
Title: [Validation of genetic polymorphisms associated to the toxicity of chemotherapy in colorectal cancer patients].
Author: Cortejoso, L|Garcia, M I|Garcia-Alfonso, P|Gravalos, C|Robles, L|Gonzalez-Haba, E|Sanjurjo, M|Lopez-Fernandez, L A
PMID: 25137161
Journal: J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:213-8.
Title: Development and validation of an ultra-high performance LC-MS/MS assay for intracellular SN-38 in human solid tumour cell lines: comparison with a validated HPLC-fluorescence method.
Author: Ghazaly, Essam|Perry, Jackie|Kitromilidou, Christiana|Powles, Thomas|Joel, Simon
PMID: 25195021
Journal: Mol Cancer Ther. 2014 Dec;13(12):3137-51.
Title: miR200c attenuates P-gp-mediated MDR and metastasis by targeting JNK2/c-Jun signaling pathway in colorectal cancer.
Author: Sui, Hua|Cai, Guo-Xiang|Pan, Shu-Fang|Deng, Wan-Li|Wang, Yu-Wei|Chen, Zhe-Sheng|Cai, San-Jun|Zhu, Hui-Rong|Li, Qi
PMID: 25205654
Journal: J Biomed Sci. 2014 Sep 4;21:89.
Title: Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms.
Author: Martinelli, Marcella|Scapoli, Luca|Cura, Francesca|Rodia, Maria Teresa|Ugolini, Giampaolo|Montroni, Isacco|Solmi, Rossella
PMID: 25355168
Journal: Oncol Res Treat. 2014;37(11):666-8, 670-2.
Title: ABCG2-meditated multidrug resistance and tumor-initiating capacity of side population cells from colon cancer.
Author: Xie, Zheng-Yuan|Lv, Ke|Xiong, Ying|Guo, Wu-Hua
PMID: 25427584
Journal: Colloids Surf B Biointerfaces. 2014 Nov 1;123:600-9.
Title: Surface engineered nanostructured lipid carriers for targeting MDR tumor: Part I. Synthesis, characterization and in vitro investigation.
Author: Negi, Lalit Mohan|Talegaonkar, Sushama|Jaggi, Manu|Verma, Anita Kamra|Verma, Ritu|Dobhal, Sheetal|Kumar, Vijay
PMID: 25454761
Journal: J Biol Chem. 2015 Jan 2;290(1):448-56.
Title: Inhibition of transient receptor potential channel 5 reverses 5-Fluorouracil resistance in human colorectal cancer cells.
Author: Wang, Teng|Chen, Zhen|Zhu, Yifei|Pan, Qiongxi|Liu, Yanjun|Qi, Xiaowei|Jin, Linfang|Jin, Jian|Ma, Xin|Hua, Dong
PMID: 25404731
Journal: Eur J Med Chem. 2015 Jan 7;89:851-62.
Title: Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents.
Author: Bandyopadhyay, Debasish|Sanchez, Jorge L|Guerrero, Adrian M|Chang, Fang-Mei|Granados, Jose C|Short, John D|Banik, Bimal K
PMID: 25462285
Journal: Genes Nutr. 2015 Jan;10(1):448.
Title: Interactions between meat intake and genetic variation in relation to colorectal cancer.
Author: Andersen, Vibeke|Vogel, Ulla
PMID: 25491747
Journal: Bioorg Med Chem. 2015 Feb 1;23(3):602-11.
Title: IND-2, a pyrimido[1'',2'':1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells.
Author: Karthikeyan, Chandrabose|Lee, Crystal|Moore, Joshua|Mittal, Roopali|Suswam, Esther A|Abbott, Kodye L|Pondugula, Satyanarayana R|Manne, Upender|Narayanan, Narayanan K|Trivedi, Piyush|Tiwari, Amit K
PMID: 25537531
Journal: Pharm Res. 2015 Jul;32(7):2205-16.
Title: Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1).
Author: Kort, Anita|Durmus, Selvi|Sparidans, Rolf W|Wagenaar, Els|Beijnen, Jos H|Schinkel, Alfred H
PMID: 25563977
Journal: J Cancer Res Clin Oncol. 2015 Sep;141(9):1613-31.
Title: Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.
Author: Golubovskaya, Vita|O'Brien, Shalana|Ho, Baotran|Heffler, Melissa|Conroy, Jeffrey|Hu, Quang|Wang, Dan|Liu, Song|Cance, William G
PMID: 25656374
Journal: Cancer Chemother Pharmacol. 2015 Apr;75(4):763-72.
Title: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.
Author: Joerger, M|Huitema, A D R|Boot, H|Cats, A|Doodeman, V D|Smits, P H M|Vainchtein, L|Rosing, H|Meijerman, I|Zueger, M|Meulendijks, D|Cerny, T D|Beijnen, J H|Schellens, J H M
PMID: 25677447
Journal: Oncotarget. 2015 Mar 20;6(8):6422-30.
Title: Variants in CDA and ABCB1 are predictors of capecitabine-related adverse reactions in colorectal cancer.
Author: Garcia-Gonzalez, Xandra|Cortejoso, Lucia|Garcia, Maria I|Garcia-Alfonso, Pilar|Robles, Luis|Gravalos, Cristina|Gonzalez-Haba, Eva|Marta, Pellicer|Sanjurjo, Maria|Lopez-Fernandez, Luis A
PMID: 25691056
Journal: Org Biomol Chem. 2015 Apr 14;13(14):4296-309.
Title: 3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity.
Author: Mudududdla, Ramesh|Guru, Santosh K|Wani, Abubakar|Sharma, Sadhana|Joshi, Prashant|Vishwakarma, Ram A|Kumar, Ajay|Bhushan, Shashi|Bharate, Sandip B
PMID: 25758415
Journal: PLoS One. 2015 Mar 20;10(3):e0119255.
Title: High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.
Author: Andersen, Vibeke|Vogel, Lotte K|Kopp, Tine Iskov|Saebo, Mona|Nonboe, Annika W|Hamfjord, Julian|Kure, Elin H|Vogel, Ulla
PMID: 25793771
Journal: ChemMedChem. 2015 May;10(5):827-35.
Title: Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells.
Author: Jun, Kyu-Yeon|Park, So-Eun|Liang, Jing Lu|Jahng, Yurngdong|Kwon, Youngjoo
PMID: 25809558
Journal: Cell Physiol Biochem. 2015;35(5):1821-30.
Title: Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
Author: Yun, Miyong|Lee, Duckgue|Park, Moon-Nyeo|Kim, Eun-Ok|Sohn, Eun Jung|Kwon, Byung-Mog|Kim, Sung-Hoon
PMID: 25833196
Journal: Bioorg Med Chem. 2015 May 1;23(9):2148-2158.
Title: Design, synthesis and in vitro cell-based evaluation of the anti-cancer activities of hispolon analogs.
Author: Balaji, Neduri V|Ramani, Modukuri V|Viana, Arabela G|Sanglard, Leticia P|White, Jason|Mulabagal, Vanisree|Lee, Crystal|Gana, Theophilus J|Egiebor, Nosa O|Subbaraju, Gottumukkala V|Tiwari, Amit K
PMID: 25842364
Journal: Diagn Pathol. 2015 Apr 16;10:26.
Title: Decreased functional activity of multidrug resistance protein in primary colorectal cancer.
Author: Micsik, Tamas|Lorincz, Andras|Mersich, Tamas|Baranyai, Zsolt|Besznyak, Istvan Jr|Dede, Kristof|Zarand, Attila|Jakab, Ferenc|Szollosi, Laszlo Krecsak|Keri, Gyorgy|Schwab, Richard|Petak, Istvan
PMID: 25885226
Journal: Biochem Biophys Res Commun. 2015 Jul 31;463(3):229-34.
Title: Chemoresistance of CD133(+) colon cancer may be related with increased survivin expression.
Author: Lee, Mi-Ra|Ji, Sun-Young|Mia-Jan, Khalilullah|Cho, Mee-Yon
PMID: 26002465
Journal: Cell Mol Biol (Noisy-le-grand). 2015 May 28;61(2):98-103.
Title: siRNA-mediated silencing of MDR1 reverses the resistance to oxaliplatin in SW480/OxR colon cancer cells.
Author: Montazami, N|Kheir Andish, M|Majidi, J|Yousefi, M|Yousefi, B|Mohamadnejad, L|Shanebandi, D|Estiar, M A|Khaze, V|Mansoori, B|Baghbani, E|Baradaran, B
PMID: 26025411
Journal: Int J Clin Exp Pathol. 2015 Mar 1;8(3):3083-9. eCollection 2015.
Title: Two SNPs of ATP-binding cassette B1 gene on the risk and prognosis of colorectal cancer.
Author: Wang, Fei|Huang, Zonghai|Zheng, Kehong|Zhao, Haiping|Hu, Wenxiu
PMID: 26045821
Journal: Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2361-70.
Title: Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway.
Author: Katayama, Kazuhiro|Kapoor, Khyati|Ohnuma, Shinobu|Patel, Atish|Swaim, William|Ambudkar, Indu S|Ambudkar, Suresh V
PMID: 26057472
Journal: Scand J Gastroenterol. 2015;50(12):1469-81.
Title: Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study.
Author: Kopp, Tine Iskov|Andersen, Vibeke|Tjonneland, Anne|Vogel, Ulla
PMID: 26109419
Journal: Tumour Biol. 2015 Dec;36(12):9499-510.
Title: Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity.
Author: Wang, Ziyuan|Zhang, Long|Ni, Zhenhua|Sun, Jian|Gao, Hong|Cheng, Zhuoan|Xu, Jianhua|Yin, Peihao
PMID: 26124005
Journal: Biochem Pharmacol. 2015 Sep 1;97(1):27-37.
Title: Vatalanib sensitizes ABCB1 and ABCG2-overexpressing multidrug resistant colon cancer cells to chemotherapy under hypoxia.
Author: To, Kenneth K W|Poon, Daniel C|Wei, Yuming|Wang, Fang|Lin, Ge|Fu, Li-wu
PMID: 26206183
Journal: Int J Oncol. 2015 Dec;47(6):2276-85.
Title: Chemosensitization by diverging modulation by short-term and long-term TNF-alpha action on ABCB1 expression and NF-kappaB signaling in colon cancer.
Author: Walther, Wolfgang|Kobelt, Dennis|Bauer, Lisa|Aumann, Jutta|Stein, Ulrike
PMID: 26463665
Journal: Oncotarget. 2015 Dec 1;6(38):40866-79.
Title: Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
Author: Wu, Shaoyu|Guo, Zhijian|Hopkins, Chad D|Wei, Ning|Chu, Edward|Wipf, Peter|Schmitz, John C
PMID: 26506423
Journal: J Cancer. 2015 Sep 3;6(11):1079-86.
Title: ABC-Transporter Expression Does Not Correlate with Response to Irinotecan in Patients with Metastatic Colorectal Cancer.
Author: Trumpi, K|Emmink, B L|Prins, A M|van Oijen, M G H|van Diest, P J|Punt, C J A|Koopman, M|Kranenburg, O|Rinkes, I H M Borel
PMID: 26516354
Journal: Hepatogastroenterology. 2015 Jun;62(140):880-6.
Title: Rapamycin-Mediated mTOR Inhibition Reverses Drug Resistance to Adriamycin in Colon Cancer Cells.
Author: Ma, Qiang|Chang, Zonghong|Wang, Wei|Wang, Biaomeng
PMID: 26902021
Journal: Pomeranian J Life Sci. 2015;61(2):137-42.
Title: [Clinical role of selected MDR1 gene polymorphisms in patients with colorectal cancer].
Author: Stanko, Grzegorz
PMID: 27141595
Journal: Gut. 2016 Sep;65(9):1494-504.
Title: Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/beta-catenin signalling pathway via suppression of activator protein 2alpha.
Author: Ma, Yanlei|Yang, Yongzhi|Wang, Feng|Moyer, Mary-Pat|Wei, Qing|Zhang, Peng|Yang, Zhe|Liu, Weijie|Zhang, Huizhen|Chen, Niwei|Wang, Hua|Wang, Huamin|Qin, Huanlong
PMID: 25994219
Journal: Tumour Biol. 2016 Jan;37(1):425-35.
Title: E-cadherin increasing multidrug resistance protein 1 via hypoxia-inducible factor-1alpha contributes to multicellular resistance in colorectal cancer.
Author: Liang, Xi|Xu, Xueqing|Wang, Fengchao|Li, Ni|He, Jianming
PMID: 26219897
Journal: Cancer Chemother Pharmacol. 2016 Mar;77(3):613-21.
Title: Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription.
Author: Ye, Pingjiang|Xing, Haibo|Lou, Fang|Wang, Kaifeng|Pan, Qin|Zhou, Xiaoyun|Gong, Liu|Li, Da
PMID: 26846508
Journal: Mol Med Rep. 2016 Mar;13(3):2583-9.
Title: The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells.
Author: Yang, Guanglei|Xu, Shuqing|Peng, Lintao|Li, Hui|Zhao, Yan|Hu, Yanfang
PMID: 26846577
Journal: Nucleic Acid Ther. 2016 Apr;26(2):111-7.
Title: Lack of Interactions Between an Antisense Oligonucleotide with 2'-O-(2-Methoxyethyl) Modifications and Major Drug Transporters.
Author: Yu, Rosie Z|Warren, Mark S|Watanabe, Tanya|Nichols, Brandon|Jahic, Mirza|Huang, Jane|Burkey, Jennifer|Geary, Richard S|Henry, Scott P|Wang, Yanfeng
PMID: 26959999
Journal: Data Brief. 2016 Mar 2;7:437-44.
Title: Data showing the circumvention of oxaliplatin resistance by vatalanib in colon cancer.
Author: To, Kenneth K W|Poon, Daniel C|Wei, Yuming|Wang, Fang|Lin, Ge|Fu, Li-Wu
PMID: 27014726
Journal: Hum Genet. 2016 Jul;135(7):675-84.
Title: A review of gigaxonin mutations in giant axonal neuropathy (GAN) and cancer.
Author: Kang, James J|Liu, Isabelle Y|Wang, Marilene B|Srivatsan, Eri S
PMID: 27023907
Journal: Cancer Med. 2016 Jul;5(7):1546-55.
Title: Regulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma.
Author: Koh, Iemasa|Hinoi, Takao|Sentani, Kazuhiro|Hirata, Eiji|Nosaka, Suguru|Niitsu, Hiroaki|Miguchi, Masashi|Adachi, Tomohiro|Yasui, Wataru|Ohdan, Hideki|Kudo, Yoshiki
PMID: 27060927
Journal: Prz Gastroenterol. 2016;11(1):35-40.
Title: The importance of G2677T/A and C3435T polymorphisms of the MDR1 gene in the aetiology of colorectal cancer.
Author: Stanko, Grzegorz|Kaminski, Marek|Bogacz, Anna|Seremak-Mrozikiewicz, Agnieszka|Kosinski, Boguslaw|Bartkowiak-Wieczorek, Joanna|Kotrych, Daniel|Czerny, Boguslaw
PMID: 27110309
Journal: Cancer Gene Ther. 2016 May;23(5):149-55.
Title: NF-kappaB decoy polyplexes decrease P-glycoprotein-mediated multidrug resistance in colorectal cancer cells.
Author: Abd Ellah, N H|Taylor, L|Ayres, N|Elmahdy, M M|Fetih, G N|Jones, H N|Ibrahim, E A|Pauletti, G M
PMID: 27125866
Journal: Anticancer Res. 2016 May;36(5):2175-9.
Title: Prediction of Early Recurrence After Curative Resection of Colorectal Liver Metastasis and Subsequent S-1 Chemotherapy.
Author: Yamauchi, Kohei|Kokuryo, Toshio|Yokoyama, Yukihiro|Uehara, Keisuke|Yamaguchi, Junpei|Nagino, Masato
PMID: 27127120
Journal: Tumour Biol. 2016 Sep;37(9):12153-12160.
Title: SH3GL1 inhibition reverses multidrug resistance in colorectal cancer cells by downregulation of MDR1/P-glycoprotein via EGFR/ERK/AP-1 pathway.
Author: Guan, Haitao|Zhao, Ping|Dai, Zhijun|Liu, Xiaoxu|Wang, Xijing
PMID: 27220321
Journal: Biochimie. 2016 Aug;127:196-204.
Title: l-carnosine dipeptide overcomes acquired resistance to 5-fluorouracil in HT29 human colon cancer cells via downregulation of HIF1-alpha and induction of apoptosis.
Author: Iovine, Barbara|Guardia, Francesca|Irace, Carlo|Bevilacqua, Maria Assunta
PMID: 27234614
Journal: Anticancer Res. 2016 Jul;36(7):3383-94.
Title: Enhanced TLR4 Expression on Colon Cancer Cells After Chemotherapy Promotes Cell Survival and Epithelial-Mesenchymal Transition Through Phosphorylation of GSK3beta.
Author: Chung, Yoon Hee|Kim, Daejin
PMID: 27354597
Journal: Oncotarget. 2016 Aug 2;7(31):49848-49858.
Title: Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization.
Author: Wang, Hao|Huang, Cheng|Zhao, Liang|Zhang, Huan|Yang, Jing Mo|Luo, Peng|Zhan, Bing-Xiang|Pan, Qing|Li, Jun|Wang, Bao-Long
PMID: 27409663
Journal: World J Gastroenterol. 2016 Jul 21;22(27):6235-45.
Title: Glucose deprivation induces chemoresistance in colorectal cancer cells by increasing ATF4 expression.
Author: Hu, Ya-Ling|Yin, Yuan|Liu, He-Yong|Feng, Yu-Yang|Bian, Ze-Hua|Zhou, Le-Yuan|Zhang, Ji-Wei|Fei, Bo-Jian|Wang, Yu-Gang|Huang, Zhao-Hui
PMID: 27468213
Journal: Biochim Biophys Acta. 2016 Nov;1863(11):2749-2757.
Title: Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels: Mechanism of 5-fluorouracil resistance in colorectal tumor cells.
Author: Hoshiba, Takashi|Tanaka, Masaru
PMID: 27558478
Journal: J Zhejiang Univ Sci B. 2016 Sep;17(9):672-82.
Title: Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1alpha.
Author: Shan, Jian-Zhen|Xuan, Yan-Yan|Zhang, Qi|Huang, Jian-Jin
PMID: 27604859
Journal: Cancer Sci. 2016 Dec;107(12):1776-1784.
Title: Wnt-beta-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer.
Author: Kobayashi, Minoru|Funayama, Ryo|Ohnuma, Shinobu|Unno, Michiaki|Nakayama, Keiko
PMID: 27709738
Journal: Int J Oncol. 2016 Dec;49(6):2558-2568.
Title: Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells.
Author: El Khoury, Flaria|Corcos, Laurent|Durand, Stephanie|Simon, Brigitte|Le Jossic-Corcos, Catherine
PMID: 27748801
Journal: Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2016 Nov 1;37(2-3):73-80.
Title: Association of Single-Nucleotide Polymorhism C3435T in the ABCB1 Gene with Opioid Sensitivity in Treatment of Postoperative Pain.
Author: Dzambazovska-Trajkovska, Vanja|Nojkov, Jordan|Kartalov, Andrijan|Kuzmanovska, Biljana|Spiroska, Tatjana|Seljmani, Redzep|Trajkovski, Gjorgji|Matevska-Geshkovska, Nadica|Dimovski, Aleksandar
PMID: 27883323
Journal: Oncotarget. 2016 Dec 27;7(52):87136-87146.
Title: RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer.
Author: Ruihua, Huang|Mengyi, Zhang|Chong, Zhao|Meng, Qiu|Xin, Ma|Qiulin, Tang|Feng, Bi|Ming, Liu
PMID: 27888624
Journal: Stem Cell Res Ther. 2016 Dec 1;7(1):181.
Title: Bile acid: a potential inducer of colon cancer stem cells.
Author: Farhana, Lulu|Nangia-Makker, Pratima|Arbit, Evan|Shango, Kathren|Sarkar, Sarah|Mahmud, Hamidah|Hadden, Timothy|Yu, Yingjie|Majumdar, Adhip P N
PMID: 27908290
Journal: Anticancer Drugs. 2017 Apr;28(4):410-420.
Title: 2-Deoxy-D-glucose suppresses the migration and reverses the drug resistance of colon cancer cells through ADAM expression regulation.
Author: Park, Ga B|Chung, Yoon H|Kim, Daejin
PMID: 28059830
Journal: Bioorg Med Chem Lett. 2017 Feb 15;27(4):797-802.
Title: Selenoesters and selenoanhydrides as novel multidrug resistance reversing agents: A confirmation study in a colon cancer MDR cell line.
Author: Gajdacs, Mario|Spengler, Gabriella|Sanmartin, Carmen|Marc, Malgorzata Anna|Handzlik, Jadwiga|Dominguez-Alvarez, Enrique
PMID: 28126516
Journal: Cell Prolif. 2017 Jun;50(3).
Title: miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression.
Author: Zhou, Hui|Lin, Changwei|Zhang, Yi|Zhang, Xiuzhong|Zhang, Chong|Zhang, Pengbo|Xie, Xingwang|Ren, Zeqiang
PMID: 28217977
Journal: Cell Cycle. 2017 Apr 3;16(7):685-692.
Title: Oncogenic retinoic acid receptor gamma knockdown reverses multi-drug resistance of human colorectal cancer via Wnt/beta-catenin pathway.
Author: Huang, Gui-Li|Song, Wei|Zhou, Pan|Fu, Qi-Rui|Lin, Chen-Lu|Chen, Qing-Xi|Shen, Dong-Yan
PMID: 28272990
Journal: Radiat Oncol. 2017 Mar 27;12(1):62.
Title: A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.
Author: Kim, Sun Young|Baek, Ji Yeon|Oh, Jae Hwan|Park, Sung Chan|Sohn, Dae Kyung|Kim, Min Ju|Chang, Hee Jin|Kong, Sun-Young|Kim, Dae Yong
PMID: 28347333
Journal: Oncol Lett. 2017 Feb;13(2):722-730.
Title: MicroRNA-93-5p increases multidrug resistance in human colorectal carcinoma cells by downregulating cyclin dependent kinase inhibitor 1A gene expression.
Author: Wang, Shi-Jun|Cao, Yun-Fei|Yang, Zu-Qing|Jiang, Zhi-Yuan|Cai, Bin|Guo, Jiao|Zhang, Sen|Zhang, Xiao-Long|Gao, Feng
PMID: 28356951
Journal: Eur Rev Med Pharmacol Sci. 2017 Mar;21(6):1226-1233.
Title: Targeting colon cancer stem cells with novel blood cholesterol drug pitavastatin.
Author: Zhang, Z-Y|Zheng, S-H|Yang, W-G|Yang, C|Yuan, W-T
PMID: 28387909
Journal: Sci Rep. 2017 Jun 9;7(1):3182.
Title: Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity.
Author: Sonowal, Himangshu|Pal, Pabitra B|Wen, Jian-Jun|Awasthi, Sanjay|Ramana, Kota V|Srivastava, Satish K
PMID: 28600556
Journal: Cancer Chemother Pharmacol. 2017 Aug;80(2):243-250.
Title: Knockdown of long non-coding RNA KCNQ1OT1 depressed chemoresistance to paclitaxel in lung adenocarcinoma.
Author: Ren, Kaiming|Xu, Ran|Huang, Jingshan|Zhao, Jungang|Shi, Wenjun
PMID: 28600629
Journal: Oncotarget. 2017 Jul 18;8(29):48012-48026.
Title: Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer.
Author: Yuan, Ze-Ting|Shi, Xiao-Jing|Yuan, Yu-Xia|Qiu, Yan-Yan|Zou, Yu|Liu, Cheng|Yu, Hui|He, Xue|Xu, Ke|Yin, Pei-Hao
PMID: 28624793
Journal: Cancer Chemother Pharmacol. 2017 Aug;80(2):395-403.
Title: Visfatin mediates doxorubicin resistance in human colorectal cancer cells via up regulation of multidrug resistance 1 (MDR1).
Author: Yan, Xiaofei|Zhao, Jian|Zhang, Rui
PMID: 28667355
Journal: PLoS One. 2017 Jul 7;12(7):e0180834.
Title: MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis.
Author: Hennenberg, Eva Maria|Eyking, Annette|Reis, Henning|Cario, Elke
PMID: 28686677
Journal: Int J Mol Sci. 2017 Jun 29;18(7). pii: ijms18071396.
Title: The Impact of Melatonin on Colon Cancer Cells' Resistance to Doxorubicin in an in Vitro Study.
Author: Fic, Magdalena|Gomulkiewicz, Agnieszka|Grzegrzolka, Jedrzej|Podhorska-Okolow, Marzenna|Zabel, Maciej|Dziegiel, Piotr|Jablonska, Karolina
PMID: 28788434
Journal: Br J Cancer. 2017 Sep 26;117(7):965-973.
Title: Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
Author: Levi, Francis|Karaboue, Abdoulaye|Saffroy, Raphael|Desterke, Christophe|Boige, Valerie|Smith, Denis|Hebbar, Mohamed|Innominato, Pasquale|Taieb, Julien|Carvalho, Carlos|Guimbaud, Rosine|Focan, Christian|Bouchahda, Mohamed|Adam, Rene|Ducreux, Michel|Milano,
PMID: 28817838
Journal: Oncotarget. 2017 May 2;8(32):52901-52912.
Title: Twist1 confers multidrug resistance in colon cancer through upregulation of ATP-binding cassette transporters.
Author: Liu, Yan-Rong|Liang, Lan|Zhao, Jian Min|Zhang, Yang|Zhang, Min|Zhong, Wei-Long|Zhang, Qiang|Wei, Jun-Jie|Li, Meng|Yuan, Jie|Chen, Shuang|Zong, Shu-Min|Liu, Hui-Juan|Meng, Jing|Qin, Yuan|Sun, Bo|Yang, Lan|Zhou, Hong-Gang|Sun, Tao|Yang, Cheng
PMID: 28881781
Journal: Oncotarget. 2017 Dec 14;8(70):115803-115816.
Title: Dishevelled1-3 contribute to multidrug resistance in colorectal cancer via activating Wnt/beta-catenin signaling.
Author: Zhang, Kun|Li, Minhui|Huang, Houyi|Li, Linpeng|Yang, Jie|Feng, Li|Gou, Junjie|Jiang, Mengju|Peng, Liaotian|Chen, Linyi|Li, Ting|Yang, Ping|Yang, Yuhan|Wang, Yuanyuan|Peng, Quekun|Dai, Xiaozhen|Zhang, Tao
PMID: 29383202
Journal: Medicine (Baltimore). 2017 Dec;96(51):e9428.
Title: Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis.
Author: Jin, Shan-Shan|Song, Wei-Juan
PMID: 29390571
Journal: J Cell Physiol. 2018 Jun;233(6):5034-5043.
Title: Multidrug resistant lncRNA profile in chemotherapeutic sensitive and resistant ovarian cancer cells.
Author: Xu, Juan|Wu, Jiacong|Fu, Chenyang|Teng, Fang|Liu, Siyu|Dai, Chencheng|Shen, Rong|Jia, Xuemei
PMID: 29219179
Journal: Curr Med Chem. 2018 Jan 4. pii: CMC-EPUB-87731.
Title: ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma.
Author: Ceballos, Maria Paula|Rigalli, Juan Pablo|Cere, Lucila Ines|Semeniuk, Mariana|Catania, Viviana Alicia|Ruiz, Maria Laura
PMID: 29303075
Journal: Biosci Rep. 2018 Feb 21;38(1). pii: BSR20171428.
Title: Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer.
Author: Hu, Hanqing|Wang, Meng|Guan, Xu|Yuan, Ziming|Liu, Zheng|Zou, Chaoxia|Wang, Guiyu|Gao, Xu|Wang, Xishan
PMID: 29371412
Journal: Oncotarget. 2017 Dec 4;9(3):3278-3291.
Title: Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells.
Author: Bhardwaj, Monika|Cho, Hee Jun|Paul, Souren|Jakhar, Rekha|Khan, Imran|Lee, Seon-Jin|Kim, Bo-Yeon|Krishnan, Manigandan|Khaket, Tejinder Pal|Lee, Hee Gu|Kang, Sun Chul
PMID: 29423046
Journal: Hum Cell. 2018 Jul;31(3):189-198.
Title: The reversal effect of Ginsenoside Rh2 on drug resistance in human colorectal carcinoma cells and its mechanism.
Author: Liu, Gui-Wei|Liu, Yan-Hua|Jiang, Guo-Sheng|Ren, Wei-Dan
PMID: 29582366
Journal: Cancer Chemother Pharmacol. 2018 Jun;81(6):1111-1119.
Title: IL-8 regulates the doxorubicin resistance of colorectal cancer cells via modulation of multidrug resistance 1 (MDR1).
Author: Du, Jing|He, Yuanqiao|Li, Peng|Wu, Weiquan|Chen, Youwei|Ruan, Hongjun
PMID: 29693201
Journal: Biomed Pharmacother. 2018 Aug;104:458-464.
Title: Nrf2/P-glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer.
Author: Sadeghi, Mohammad Reza|Jeddi, Farhad|Soozangar, Narges|Somi, Mohammad Hossein|Shirmohamadi, Masoud|Khaze, Vahid|Samadi, Nasser
PMID: 29793178
Journal: Mol Oncol. 2018 Sep;12(9):1639-1655.
Title: Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Author: Bruun, Jarle|Sveen, Anita|Barros, Rita|Eide, Peter W|Eilertsen, Ina|Kolberg, Matthias|Pellinen, Teijo|David, Leonor|Svindland, Aud|Kallioniemi, Olli|Guren, Marianne G|Nesbakken, Arild|Almeida, Raquel|Lothe, Ragnhild A
PMID: 29900672
Journal: Oncol Lett. 2018 Jun;15(6):9673-9680.
Title: Sesquiterpene lactone 6-O-angeloylplenolin reverses vincristine resistance by inhibiting YB-1 nuclear translocation in colon carcinoma cells.
Author: Li, Changlong|Wu, Hezhen|Yang, Yanfang|Liu, Jianwen|Chen, Zhenwen
PMID: 29928343
Journal: Biomed Pharmacother. 2018 Oct;106:624-636.
Title: Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives.
Author: Sroda-Pomianek, Kamila|Michalak, Krystyna|Swiatek, Piotr|Pola, Andrzej|Palko-Labuz, Anna|Wesolowska, Olga
PMID: 29990852
Journal: Biosci Rep. 2018 Sep 20;38(5). pii: BSR20180790.
Title: LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer.
Author: Wang, Lin|Zhang, Xufeng|Sheng, Li|Qiu, Chun|Luo, Rongcheng
PMID: 30126852
Journal: Daru. 2018 Sep 12. pii: 10.1007/s40199-018-0210-8.
Title: Effect of Cinnamic acid and FOLFOX in diminishing side population and downregulating cancer stem cell markers in colon cancer cell line HT-29.
Author: Soltanian, Sara|Riahirad, Helia|Pabarja, Athareh|Jafari, Elham|Khandani, Behjat Kalantari
PMID: 30209760
Journal: Pharmacol Res. 2018 Sep 11;136:133-139.
Title: Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
Author: Salvador-Martin, Sara|Garcia-Gonzalez, Xandra|Garcia, Maria I|Blanco, Carolina|Garcia-Alfonso, Pilar|Robles, Luis|Gravalos, Cristina|Pachon, Vanessa|Longo, Federico|Martinez, Virginia|Sanjurjo-Saez, Maria|Lopez-Fernandez, Luis A
PMID: 30213564
Journal: Onco Targets Ther. 2018 Aug 31;11:5315-5324.
Title: Eukaryotic translation initiation factor 3 subunit G (EIF3G) resensitized HCT116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1.
Author: Yang, Chenggang|Liu, Xin|Li, Chaobin|Li, Shuangjing|Du, Wenfeng|Yang, Daogui
PMID: 30214237
Journal: J Pathol. 2018 Oct 10.
Title: Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1.
Author: Ashley, Neil|Ouaret, Djamila|Bodmer, Walter F
PMID: 30306567
Journal: Biomed Pharmacother. 2018 Sep 28;108:1070-1080.
Title: Through oxaliplatin resistance induction in colorectal cancer cells, increasing ABCB1 level accompanies decreasing level of miR-302c-5p, miR-3664-5p and miR-129-5p.
Author: Ghanbarian, Marzieh|Afgar, Ali|Yadegarazari, Reza|Najafi, Rezvan|Teimoori-Toolabi, Ladan
PMID: 30372807