Primary Site >> Stomach Cancer

Gene >> ZHX2

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Ref: Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer.
PMID: 3862088
Ref: A murine monoclonal antibody that recognizes an extracellular domain of the human c-erbB-2 protooncogene product.
PMID: 2565325
Ref: Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells.
PMID: 9341140
Ref: Oxidative stress activates the human histidine decarboxylase promoter in AGS gastric cancer cells.
PMID: 9722530
Ref: Gastrin-stimulated gastric epithelial cell invasion: the role and mechanism of increased matrix metalloproteinase 9 expression.
PMID: 11971760
Ref: Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements.
PMID: 12509426
Ref: Expression of NGF family and their receptors in gastric carcinoma: a cDNA microarray study.
PMID: 12854135
Ref: Transcriptional regulation of the human trefoil factor, TFF1, by gastrin.
PMID: 12891554
Ref: BRAF and KRAS mutations in stomach cancer.
PMID: 14534542
Ref: BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency.
PMID: 14668801
Ref: Inhibition of gastric cancer angiogenesis by vector-based RNA interference for Raf-1.
PMID: 15662129
Ref: Mutational analysis of the ARAF gene in human cancers.
PMID: 15676015
Ref: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad.
PMID: 15751984
Ref: Results of a phase I trial of sorafenib (BAY 43-9006) in combination with oxaliplatin in patients with refractory solid tumors, including colorectal cancer.
PMID: 16197622
Ref: FGF signaling network in the gastrointestinal tract (review).
PMID: 16773196
Ref: Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients.
PMID: 16786117
Ref: [Effect of B-RAF-specific RNA interference on gastric cancer BGC823 cell line].
PMID: 17548320
Ref: Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling.
PMID: 18081943
Ref: RNAi-mediated inhibition of Raf-1 leads to decreased angiogenesis and tumor growth in gastric cancer.
PMID: 19029826
Ref: AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer.
PMID: 19723882
Ref: Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma.
PMID: 20526349
Ref: Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis.
PMID: 21346147
Ref: New targeted therapies for gastric cancer.
PMID: 21406037
Ref: Discovery of a novel B-Raf fusion protein related to c-Met drug resistance.
PMID: 21936566
Ref: Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells.
PMID: 21676900
Ref: A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation.
PMID: 22745804
Ref: RKIP and 14-3-3epsilon exert an opposite effect on human gastric cancer cells SGC7901 by regulating the ERK/MAPK pathway differently.
PMID: 22899242
Ref: Ribonucleotide reductase large subunit M1 predicts poor survival due to modulation of proliferative and invasive ability of gastric cancer.
PMID: 23922955
Ref: Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer.
PMID: 24465527
Ref: Clinicopathological features and prognostic roles of KRAS, BRAF, PIK3CA and NRAS mutations in advanced gastric cancer.
PMID: 24774510
Ref: Anti-tumor activity of oridonin on SNU-5 subcutaneous xenograft model via regulation of c-Met pathway.
PMID: 24916572
Ref: RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224.
PMID: 25017365
Ref: Association between raf kinase inhibitor protein loss and prognosis in cancers of the digestive system: a meta-analysis.
PMID: 25171481
Ref: Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells.
PMID: 25473895
Ref: RASAL1 attenuates gastric carcinogenesis in nude mice by blocking RAS/ERK signaling.
PMID: 25735335
Ref: Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer.
PMID: 26091251
Ref: BRD7: a novel tumor suppressor gene in different cancers.
PMID: 27158366
Ref: Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation.
PMID: 27437872
Ref: Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
PMID: 27699948
Ref: Gastrin Enhances Autophagy and Promotes Gastric Carcinoma Proliferation via Inducing AMPKalpha.
PMID: 28059052
Ref: Hepatocyte growth factor/MET in cancer progression and biomarker discovery.
PMID: 28064454
Ref: Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway.
PMID: 28114937
Ref: Bidirectional alteration of Cav-1 expression is associated with mitogenic conversion of its function in gastric tumor progression.
PMID: 29141593
Ref: Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival.
PMID: 29872697
Ref: Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway.
PMID: 29393362
Ref: Resveratrol inhibits Interleukin-6 induced invasion of human gastric cancer cells.
PMID: 29710474
Ref: Acquired JHDM1D-BRAF fusion confers resistance to FGFR inhibition in FGFR2- amplified gastric cancer.
PMID: 30045926