Primary Site >> Colorectal Cancer
Gene >> ULK1
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Ref: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. PMID: 22406476 |
Ref: AMP-activated protein kinase (AMPK)/Ulk1-dependent autophagic pathway contributes to C6 ceramide-induced cytotoxic effects in cultured colorectal cancer HT-29 cells. PMID: 23508272 |
Ref: Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells. PMID: 24842158 Ref: Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells. PMID: 24955726 Ref: Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells. PMID: 25475140 |
Ref: High expression levels of unc-51-like kinase 1 as a predictor of poor prognosis in colorectal cancer. PMID: 26622714 |
Ref: BRAF V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells. PMID: 26750638 Ref: Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status. PMID: 27444698 |
Ref: The BAX gene as a candidate for negative autophagy-related genes regulator on mRNA levels in colorectal cancer. PMID: 28035578 Ref: Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer. PMID: 28492544 Ref: MACC1 induces autophagy to regulate proliferation, apoptosis, migration and invasion of squamous cell carcinoma. PMID: 28791376 Ref: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells. PMID: 29066806 Ref: Curcumin synergizes with 5-fluorouracil by impairing AMPK/ULK1-dependent autophagy, AKT activity and enhancing apoptosis in colon cancer cells with tumor growth inhibition in xenograft mice. PMID: 29273065 |
Ref: Intratumoral Heterogeneity of Somatic Mutations for NRIP1, DOK1, ULK1, ULK2, DLGAP3, PARD3 and PRKCI in Colon Cancers. PMID: 28844109 Ref: Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy. PMID: 29921885 Ref: Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells. PMID: 29928348 Ref: Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. PMID: 30087121 Ref: Sicilian Litchi Fruit Extracts Induce Autophagy versus Apoptosis Switch in Human Colon Cancer Cells. PMID: 30322062 |