Primary Site >> Colorectal Cancer
Gene >> TNIK
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Ref: The kinase TNIK is an essential activator of Wnt target genes. PMID: 19816403 |
Ref: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth. PMID: 20530691 Ref: Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation. PMID: 20566648 |
Ref: Enormous influence of TNIK knockdown on intracellular signals and cell survival. PMID: 21710359 |
Ref: Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. PMID: 22285593 |
Ref: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. PMID: 23232060 Ref: Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. PMID: 23585443 |
Ref: The essential role of TNIK gene amplification in gastric cancer growth. PMID: 24566388 |
Ref: Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer. PMID: 26499327 Ref: Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer. PMID: 26542362 |
Ref: Targeting the Wnt signaling pathway in colorectal cancer. PMID: 26439805 Ref: TNIK inhibition abrogates colorectal cancer stemness. PMID: 27562646 Ref: Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor. PMID: 27650168 |
Ref: Emergence of TNIK inhibitors in cancer therapeutics. PMID: 28208209 Ref: The emergence of TNIK as a therapeutic target for colorectal cancer. PMID: 28281900 |