Primary Site >> Colorectal Cancer
Gene >> TIMP3
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Ref: Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3. PMID: 8824499 |
Ref: TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma. PMID: 9184186 Ref: TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells. PMID: 9344510 |
Ref: Identification of novel genes that are differentially expressed in human colorectal carcinoma. PMID: 9748578 |
Ref: Increased expression of tissue inhibitor of metalloproteinases type 1 (TIMP-1) in a more tumourigenic colon cancer cell line. PMID: 11113862 Ref: [Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]. PMID: 11832095 |
Ref: The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase. PMID: 14676107 |
Ref: Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia. PMID: 15122305 Ref: The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer. PMID: 15161007 Ref: Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia. PMID: 15386372 Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 Ref: Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. PMID: 15623598 |
Ref: Progressive methylation during the serrated neoplasia pathway of the colorectum. PMID: 15389252 Ref: Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal tumours displaying either microsatellite stability (MSS) or instability (MSI). PMID: 15890246 Ref: Aberrant CpG island methylation in early-onset sporadic gastric carcinoma. PMID: 16075282 Ref: Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. PMID: 16207479 |
Ref: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay. PMID: 16369045 Ref: DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. PMID: 16421593 Ref: CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer. PMID: 16708352 Ref: APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer. PMID: 16981189 |
Ref: The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. PMID: 17087942 Ref: TIMP-3 and Phosphatidylinositol 3-kinase genes were found to be related to the progression of colon cancer in a comparison of pneumoperitoneum and laparotomy in a murine model. PMID: 17342361 Ref: Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer. PMID: 17455256 Ref: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. PMID: 17615082 Ref: Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa. PMID: 17640302 Ref: Clinicopathologic significance of BAG1 and TIMP3 expression in colon carcinoma. PMID: 17657847 |
Ref: CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria. PMID: 18437011 Ref: Epigenetic signatures of familial cancer are characteristic of tumor type and family category. PMID: 18559504 Ref: Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature. PMID: 18776587 |
Ref: Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. PMID: 20572039 Ref: DNA methylation in patients with colorectal cancer--correlation with some clinical and morphological features and with local tumour invasion. PMID: 20836393 |
Ref: Matrix metalloproteinase-9 is a prognostic marker to predict survival of patients who underwent surgery due to rectal carcinoma. PMID: 21212604 Ref: Methylation profiling of rectal cancer identifies novel markers of early-stage disease. PMID: 21360524 Ref: Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis. PMID: 21406167 Ref: DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PMID: 22132162 |
Ref: Targeting of colorectal cancer growth, metastasis, and anti-apoptosis in BALB/c nude mice via APRIL siRNA. PMID: 22170570 Ref: Effect of the expression of matrix metalloproteases and their tissue inhibitors on survival of patients with resectable colorectal cancer. PMID: 22488635 Ref: Quantitative analysis of cancer-associated gene methylation connected to risk factors in Korean colorectal cancer patients. PMID: 22880157 Ref: Tissue inhibitor of metalloproteinases-3 transfer suppresses malignant behaviors of colorectal cancer cells. PMID: 23037807 |
Ref: Gene methylation in rectal cancer: predictive marker of response to chemoradiotherapy? PMID: 23702823 Ref: MicroRNA-191 correlates with poor prognosis of colorectal carcinoma and plays multiple roles by targeting tissue inhibitor of metalloprotease 3. PMID: 24050546 Ref: Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRgamma activation. PMID: 24190430 |
Ref: MicroRNA-191 correlates with poor prognosis of colorectal carcinoma and plays multiple roles by targeting tissue inhibitor of metalloprotease 3. PMID: 24195505 |
Ref: Matrix metalloproteinases MMP1, MMP2, MMP9 and their tissue inhibitors TIMP1, TIMP2, TIMP3 in head and neck cancer: an immunohistochemical study. PMID: 27386931 |
Ref: Long Noncoding RNA BC032913 as a Novel Therapeutic Target for Colorectal Cancer that Suppresses Metastasis by Upregulating TIMP3. PMID: 28918047 |
Ref: Fluorescent Nanodiamonds are Efficient, Easy-to-Use Cyto-Compatible Vehicles for Monitored Delivery of Non-Coding Regulatory RNAs. PMID: 29883564 Ref: The stress response gene ATF3 is a direct target of the Wnt/beta-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells. PMID: 29966001 Ref: CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases. PMID: 30185549 |