Primary Site >> Colorectal Cancer
Gene >> TGFBR1
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Ref: The mannose 6-phosphate/insulin-like growth factor-II receptor is a substrate of type V transforming growth factor-beta receptor. PMID: 10391950 Ref: TbetaR-I(6A) is a candidate tumor susceptibility allele. PMID: 10582683 |
Ref: [Mechanism of resistance to growth inhibition by transforming growth factor-beta 1 (TGF-beta 1) in primary lung cancer and new molecular targets in therapy]. PMID: 10945024 Ref: Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency. PMID: 11030155 |
Ref: Aberrant transforming growth factor-beta signaling in azoxymethane-induced mouse colon tumors. PMID: 11536370 |
Ref: TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies. PMID: 12947057 |
Ref: Transforming growth factor-beta signaling is differentially inhibited by Smad2D450E and Smad3D407E. PMID: 14720321 |
Ref: TGFBR1*6A may contribute to hereditary colorectal cancer. PMID: 15860866 Ref: Somatic acquisition and signaling of TGFBR1*6A in cancer. PMID: 16204663 |
Ref: Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. PMID: 17047044 |
Ref: [Colorectal carcinogenesis. 1. Hereditary predisposition and colorectal cancer]. PMID: 17369756 Ref: Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia? PMID: 17507611 Ref: Lack of an association between the TGFBR1*6A variant and colorectal cancer risk. PMID: 17575241 Ref: TGF-beta signaling alterations and susceptibility to colorectal cancer. PMID: 17613544 Ref: Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development. PMID: 17890272 |
Ref: Germline allele-specific expression of TGFBR1 confers an increased risk of colorectal cancer. PMID: 18703712 Ref: Colorectal cancers in patients with the (9A/6A) polymorphism of TGFBR1 exhibit lesser inter-(simple sequence repeat) PCR genomic instability and present clinically at greater age. PMID: 18778720 |
Ref: Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development. PMID: 19147584 Ref: TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk. PMID: 19401691 Ref: Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. PMID: 19509225 Ref: The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study. PMID: 19538729 Ref: The Int7G24A variant of transforming growth factor-beta receptor type I is a risk factor for colorectal cancer in the male Spanish population: a case-control study. PMID: 19930569 |
Ref: TGFBR1*6A/9A polymorphism and cancer risk: a meta-analysis of 13,662 cases and 14,147 controls. PMID: 19882361 Ref: Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression. PMID: 19998449 Ref: Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition. PMID: 20368424 Ref: Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs. PMID: 20500843 Ref: Tgf-beta signaling alterations and colon cancer. PMID: 20517689 Ref: Allele-specific expression of TGFBR1 in colon cancer patients. PMID: 20705955 |
Ref: No association between germline allele-specific expression of TGFBR1 and colorectal cancer risk in Caucasian and Ashkenazi populations. PMID: 21224855 Ref: A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22. PMID: 21811255 |
Ref: The association of polymorphisms on TGFBR1 and colorectal cancer risk: a meta-analysis. PMID: 21858550 Ref: TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer. PMID: 22292045 Ref: Debate about TGFBR1 and the susceptibility to colorectal cancer. PMID: 22347533 Ref: Association between TGFBR1 polymorphisms and cancer risk: a meta-analysis of 35 case-control studies. PMID: 22905183 Ref: Dependency of colorectal cancer on a TGF-beta-driven program in stromal cells for metastasis initiation. PMID: 23153532 |
Ref: Genetic variations in the TGFbeta signaling pathway, smoking and risk of colorectal cancer in a Chinese population. PMID: 23275154 Ref: Clinical applications of gene expression in colorectal cancer. PMID: 23730510 |
Ref: TGFBR1*6A polymorphism in sporadic and familial colorectal Carcinoma: a case-control study and systematic literature review. PMID: 24880985 Ref: Little evidence for association between the TGFBR1*6A variant and colorectal cancer: a family-based association study on non-syndromic family members from Australia and Spain. PMID: 24981199 Ref: TGFBR1 and cancer susceptibility. PMID: 25125747 |
Ref: Mutational Profiles Reveal an Aberrant TGF-beta-CEA Regulated Pathway in Colon Adenomas. PMID: 27100181 Ref: Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC). PMID: 27234654 Ref: High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis. PMID: 27409174 |
Ref: Genetic variants in the TGFbeta-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue. PMID: 28061442 Ref: TGFbeta engages MEK/ERK to differentially regulate benign and malignant pancreas cell function. PMID: 28368414 |
Ref: TGFBR1*6A is a potential modifier of migration and invasion in colorectal cancer cells. PMID: 29467907 Ref: The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs. PMID: 29636593 Ref: A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk. PMID: 29971498 Ref: The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs. PMID: 29986714 |