Primary Site >> Colorectal Cancer
Gene >> TAOK2
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Ref: [A study on postoperative long-term continuous immuno-chemotherapy with PSK and 5-FUDS for advanced gastric and colo-rectal cancers]. PMID: 6411000 |
Ref: [Clinical results of a randomized controlled trial on the effect of adjuvant immunochemotherapy using Esquinon and Krestin in patients with curatively resected gastric cancer. Cooperative Study Group of Cancer Immunochemotherapy, Tokai Gastrointestinal On PMID: 3947108 |
Ref: [Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku]. PMID: 3136695 |
Ref: [Randomized controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum]. PMID: 2500070 |
Ref: Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer. PMID: 2198088 |
Ref: [Immunological competence and effect of PSK in patients with gastric cancer and colon cancer: preliminary report]. PMID: 1508143 Ref: Antitumor effect of PSK at a distant site: tumor-specific immunity and combination with other chemotherapeutic agents. PMID: 1517151 Ref: Immunomodulation by orally administered protein-bound polysaccharide PSK in patients with gastrointestinal cancer. PMID: 1622733 Ref: Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa). PMID: 1735313 |
Ref: Enhancement of the antitumor effect by the concurrent use of a monoclonal antibody and the protein-bound polysaccharide PSK in mice bearing a human cancer cell line. PMID: 7919129 |
Ref: [Antitumor effect of intratumoral administration of BRM: inhibition of tumor cell invasion in vitro]. PMID: 7574777 Ref: Antimetastatic effects of PSK (Krestin), a protein-bound polysaccharide obtained from basidiomycetes: an overview. PMID: 7606203 Ref: Polysaccharide preparation PSK augments the proliferation and cytotoxicity of tumor-infiltrating lymphocytes in vitro. PMID: 7762991 Ref: In vitro reactivity to a protein-bound polysaccharide PSK of peripheral blood lymphocytes from patients with gastrointestinal cancer. PMID: 8572620 |
Ref: [Regional adoptive immunotherapy using activated lymphocytes]. PMID: 8854802 Ref: Antitumor effect of the angiogenesis inhibitor TNP-470 and its combination effect with 5-FU and PSK in colon 26 tumors. PMID: 21594334 |
Ref: Oral administration of PSK can improve the impaired anti-tumor CD4+ T-cell response in gut-associated lymphoid tissue (GALT) of specific-pathogen-free mice. PMID: 9033641 Ref: Direct tumor growth suppressive effect of melanoidin extracted from immunomodulator-PSK. PMID: 10851484 |
Ref: [Surgery and multidisciplinary treatment for colorectal cancer]. PMID: 9474930 Ref: Direct action of a protein-bound polysaccharide, PSK, on transforming growth factor-beta. PMID: 9858065 |
Ref: Long-term survival after immunochemotherapy for juvenile colon cancer with peritoneal dissemination: a case report. PMID: 11032941 |
Ref: Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer. PMID: 11901535 Ref: Effectiveness of immunochemotherapy with PSK, a protein-bound polysaccharide, in colorectal cancer and changes of tumor marker. PMID: 11956642 |
Ref: A randomized controlled trial of postoperative adjuvant immunochemotherapy for colorectal cancer with oral medicines. PMID: 12792790 |
Ref: Long-term effect of 5-fluorouracil enhanced by intermittent administration of polysaccharide K after curative resection of colon cancer. A randomized controlled trial for 7-year follow-up. PMID: 13680286 Ref: Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: identification of responders incorporating the age factor. PMID: 14767513 Ref: Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. PMID: 14997197 Ref: Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer. PMID: 15305190 Ref: Gene expression in response to anti-tumour intervention by polysaccharide-K (PSK) in colorectal carcinoma cells. PMID: 15547752 |
Ref: Effects of PSK on T and dendritic cells differentiation in gastric or colorectal cancer patients. PMID: 15816609 Ref: Preoperative CEA and PPD values as prognostic factors for immunochemotherapy using PSK and 5-FU. PMID: 15865094 Ref: [A case of metastatic submandibular lymphnode treated successfully with palliative oral (5-FU + PSK) chemotherapy in the elderly]. PMID: 15984533 Ref: [Usefulness in predicting parameters for the selection of responders who received immunochemotherapy with PSK in patients with colorectal cancer]. PMID: 16315871 |
Ref: Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials. PMID: 16133112 Ref: Protective effect of a protein-bound polysaccharide, PSK, on CLP-induced sepsis in mice transplanted orthotopically with colon tumor. PMID: 16369184 Ref: Beneficial effects of protein-bound polysaccharide K plus tegafur/uracil in patients with stage II or III colorectal cancer: analysis of immunological parameters. PMID: 16525672 Ref: [A patient with hepatic, pulmonary, and nodal metastases of colon cancer responding to CPT-11/TS-1 therapy]. PMID: 16770105 |
Ref: Enhancement of antitumor effect of tegafur/uracil (UFT) plus leucovorin by combined treatment with protein-bound polysaccharide, PSK, in mouse models. PMID: 17764620 |
Ref: [Ten cases of advanced gastro-intestinal cancer that required preoperative dosage of PSK]. PMID: 20037293 Ref: [A case of ascending colon cancer successfully treated for synchronous liver metastases with mFOLFOX6 after a resection of the primary tumor]. PMID: 20037364 |
Ref: PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients. PMID: 20229169 Ref: [Immunoregulatory effects of PSK on the Th1/Th2 balance and regulatory T-cells in patients with colorectal cancer]. PMID: 21224532 |
Ref: [PSK decreased FOLFOX4-induced peripheral neuropathy and bone marrow suppression in patients with metastatic colorectal cancer]. PMID: 21566440 Ref: A review of the anti-tumor effect of the combined administration of a cyclooxygenase-2 selective inhibitor and a non-specific immunostimulant protein-bound polysaccharide on an advanced colon cancer model using colon cancer cell lines. PMID: 22866112 |
Ref: Direct inhibition of the transforming growth factor-beta pathway by protein-bound polysaccharide through inactivation of Smad2 signaling. PMID: 22034928 Ref: Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN((R))): review of development and future perspectives. PMID: 22139128 Ref: [Two cases of long-term survival of metastatic colorectal cancer following treatment with polysaccharide K and mFOLFOX6 therapy]. PMID: 23267885 |
Ref: The expression of integrins is decreased in colon cancer cells treated with polysaccharide K. PMID: 23427003 Ref: Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers. PMID: 24100378 Ref: Protein-bound polysaccharide K reduced the invasive ability of colon cancer cell lines. PMID: 24222121 Ref: [Subset analysis of preoperative lymphocyte ratio in stage II or III colorectal cancer patients treated with oral tegafur-uracil and protein-bound polysaccharide K]. PMID: 24335363 Ref: [Analysis of the eligibility of elderly colorectal cancer patients for adjuvant chemotherapy combined with polysaccharide K]. PMID: 24393859 Ref: [Clinical significance of neutrophil to lymphocyte ratio in colorectal cancer patients receiving adjuvant chemotherapy combined with polysaccharide-K]. PMID: 24394021 Ref: Prognostic markers for immunochemotherapy using tegafur -uracil (UFT) and protein-bound polysaccharide K (PSK). PMID: 24693683 |