Primary Site >> Colorectal Cancer
Gene >> SP3
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Ref: Transcriptional regulation of the non-specific cross-reacting antigen gene, a member of the carcinoembryonic antigen gene family up-regulated in colorectal carcinomas. PMID: 9654079 |
Ref: Sp3 is a transcriptional repressor of transforming growth factor-beta receptors. PMID: 11027677 Ref: The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters. PMID: 11212251 Ref: 5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3. PMID: 11443124 |
Ref: Altered expression of the receptor and ligand in the TGF beta signaling pathway in diffusely infiltrating colon carcinoma. PMID: 12552954 |
Ref: Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site. PMID: 12626711 |
Ref: Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells. PMID: 14767471 Ref: Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. PMID: 15107822 |
Ref: Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins. PMID: 15883203 Ref: A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region. PMID: 16261846 |
Ref: Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. PMID: 16533812 |
Ref: Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. PMID: 17297470 Ref: Analysis of specific transcriptional regulators as early predictors of independent prognostic relevance in resected colorectal cancer. PMID: 17317820 Ref: Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. PMID: 17409437 Ref: Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation. PMID: 17764926 |
Ref: Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis. PMID: 17945194 Ref: Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. PMID: 18628250 |
Ref: Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds. PMID: 19197985 Ref: Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells. PMID: 19582879 Ref: Mutated ras induced PLD1 gene expression through increased Sp1 transcription factor. PMID: 19994725 |
Ref: Pdcd4, a colon cancer prognostic that is regulated by a microRNA. PMID: 19836969 Ref: Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction. PMID: 20068171 Ref: Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter. PMID: 20199127 Ref: Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure-activity relationship modeling. PMID: 20526854 |
Ref: GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway. PMID: 21156786 Ref: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. PMID: 21864401 Ref: Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells. PMID: 21919647 |
Ref: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. PMID: 23110215 Ref: Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues. PMID: 23133566 Ref: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. PMID: 23194063 |
Ref: The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis. PMID: 23471840 Ref: Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a. PMID: 23530649 Ref: [Successful treatment of a patient using mFOLFOX6 after laparoscopic surgery for rectal cancer with peritoneal dissemination]. PMID: 23863744 Ref: The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells. PMID: 24030632 Ref: REACTIVE OXYGEN SPECIES AND COLORECTAL CANCER. PMID: 25584043 |
Ref: Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors. PMID: 23670891 Ref: Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a. PMID: 24173369 Ref: Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators. PMID: 24948597 Ref: Immunohistochemical results of HER2/neu protein expression assessed by rabbit monoclonal antibodies SP3 and 4B5 in colorectal carcinomas. PMID: 25120833 Ref: HDAC8 and STAT3 repress BMF gene activity in colon cancer cells. PMID: 25321483 |
Ref: Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors. PMID: 26673922 |
Ref: Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells. PMID: 26807725 Ref: Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells. PMID: 26967243 |
Ref: Induction of cell differentiation activates transcription of the Sarco/Endoplasmic Reticulum calcium-ATPase 3 gene (ATP2A3) in gastric and colon cancer cells. PMID: 27433831 |
Ref: E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells. PMID: 29901191 Ref: Bortezomib Targets Sp Transcription Factors in Cancer Cells. PMID: 30115673 |