Primary Site >> Liver Cancer
Gene >> SERPINE1
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Ref: Plasminogen activators and plasminogen activator inhibitor in malignant and non-malignant ascitic fluid. PMID: 2852112 |
Ref: [Fibrinolytic activity in patients undergoing hepatic transplantation]. PMID: 2496627 Ref: Plasminogen activator inhibitor 1: biosynthesis and mRNA level are increased by insulin in cultured human hepatocytes. PMID: 2683191 |
Ref: Human HuH-7 hepatoma cells express urokinase and plasminogen activator inhibitor-1: identification, characterization and regulation by inflammatory mediators. PMID: 1371701 |
Ref: Diagnostic efficacy of plasma urokinase-type plasminogen activator and plasminogen activator inhibitor-2 in differentiation of hepatocellular carcinoma from cirrhosis. PMID: 8571313 |
Ref: Postoperative adjuvant arterial infusion chemotherapy for patients with hepatocellular carcinoma. PMID: 8975940 |
Ref: [Percutaneous ethanol and acetic acid injection for liver metastasis from colon cancer--two case reports]. PMID: 9571976 Ref: Human hepatoma cells rich in P-glycoprotein display enhanced in vitro invasive properties compared to P-glycoprotein-poor hepatoma cells. PMID: 9802060 Ref: [Inhibitor of plasminogen activator 1 (PAI-1) in hepatocellular carcinoma]. PMID: 11825444 Ref: [Changes of PAI-1 and biological behaviour of human hepatocellular carcinoma in metastatic model of nude mice]. PMID: 11825501 |
Ref: Clinical significance of urokinase-type plasminogen activator activity in hepatocellular carcinoma. PMID: 10824888 Ref: Expression of urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor, and plasminogen activator inhibitor-1 and -2 in hepatocellular carcinoma. PMID: 10849328 Ref: Invasion and metastasis of hepatocellular carcinoma in relation to urokinase-type plasminogen activator, its receptor and inhibitor. PMID: 11079728 |
Ref: Clinical relevance of the plasminogen activator inhibitor type 1--a multifaceted proteolytic factor. PMID: 11455216 Ref: Variability in aflatoxin-albumin adduct levels and effects of hepatitis B and C virus infection and glutathione S-transferase M1 and T1 genotype. PMID: 11564620 Ref: Metastatic human hepatocellular carcinoma models in nude mice and cell line with metastatic potential. PMID: 11819839 |
Ref: The prognostic molecular markers in hepatocellular carcinoma. PMID: 12046056 |
Ref: Quantitative expression of protein markers of plasminogen activation system in prognosis of colorectal cancer. PMID: 12619063 |
Ref: Altered expression of TGF-beta receptors in hepatocellular carcinoma--effects of a constitutively active TGF-beta type I receptor mutant. PMID: 15775675 Ref: Percutaneous ablation therapy for hepatocellular carcinoma: current practice and future perspectives. PMID: 15850062 |
Ref: [The effects of tumor antigen gene OVA66 on biological characteristics of tumor cells]. PMID: 16507255 |
Ref: Percutaneous ultrasound-guided ablation of BW7756-hepatoma using ethanol or acetic acid in a rat model. PMID: 18078519 |
Ref: Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. PMID: 18282651 Ref: PAI-1, t-PA and circulating hTERT DNA as related to virus infection in liver carcinogenesis. PMID: 18383849 Ref: Ghrelin attenuates plasminogen activator inhibitor-1 production induced by tumor necrosis factor-alpha in HepG2 cells via NF-kappaB pathway. PMID: 18700166 |
Ref: MTHFR C677TT, PAI1 4G-4G, V Leiden Q506, and prothrombin G20210A in hepatocellular carcinoma with and without portal vein thrombosis. PMID: 18618228 Ref: Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression. PMID: 19563779 Ref: Plumbagin inhibits invasion and migration of liver cancer HepG2 cells by decreasing productions of matrix metalloproteinase-2 and urokinase- plasminogen activator. PMID: 19624766 |
Ref: Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells. PMID: 19895793 Ref: Evaluation of the association of urokinase plasminogen activator system gene polymorphisms with susceptibility and pathological development of hepatocellular carcinoma. PMID: 20706793 Ref: Rodent-specific hypoxia response elements enhance PAI-1 expression through HIF-1 or HIF-2 in mouse hepatoma cells. PMID: 21042733 |
Ref: Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by beta-naphthoflavone involving TNFalpha-signaling due to oxidative cellular stress in rats. PMID: 21295105 Ref: Various effects of hepatoma-derived growth factor on cell growth, migration and invasion of breast cancer and prostate cancer cells. PMID: 21567096 Ref: PPARgamma activation induces acute PAI-1 gene expression in the liver but not in adipose tissues of diabetic model mice. PMID: 21757225 Ref: Transarterial chemoembolization for hepatocellular carcinoma: significance of extrahepatic collateral supply. PMID: 21921335 |
Ref: Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss. PMID: 21898503 Ref: Stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells. PMID: 22171322 Ref: Korean Red Ginseng Suppresses Metastasis of Human Hepatoma SK-Hep1 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen Activator. PMID: 22570673 Ref: Threshold dose of liver tumor promoting effect of beta-naphthoflavone in rats. PMID: 22687991 Ref: Molecular mechanism inhibiting human hepatocarcinoma cell invasion by 6-shogaol and 6-gingerol. PMID: 22714996 Ref: Influence of plasminogen activator inhibitor-1 (SERPINE1) 4G/5G polymorphism on circulating SERPINE-1 antigen expression in HCC associated with viral infection. PMID: 22798504 |
Ref: Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population. PMID: 24455271 |
Ref: Compound Astragalus and Salvia miltiorrhiza extract suppresses hepatocellular carcinoma progression by inhibiting fibrosis and PAI-1 mRNA transcription. PMID: 24247078 Ref: Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-beta1-Smad4-PAI-1 axis. PMID: 24337404 Ref: Pre-retrieval reperfusion decreases cancer recurrence after rat ischemic liver graft transplantation. PMID: 24713189 |
Ref: Axl activates autocrine transforming growth factor-beta signaling in hepatocellular carcinoma. PMID: 25251599 Ref: HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma. PMID: 25489981 Ref: Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-beta/Smad signaling in hepatocellular carcinoma by multi-target mechanism. PMID: 25934513 Ref: Circulating Levels of PAI-1 and SERPINE1 4G/4G Polymorphism Are Predictive of Poor Prognosis in HCC Patients Undergoing TACE. PMID: 26310373 |
Ref: Chlordecone potentiates hepatic fibrosis in chronic liver injury induced by carbon tetrachloride in mice. PMID: 26853152 Ref: Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. PMID: 27092498 Ref: PAI-1 4G-4G, MTHFR 677TT, V Leiden 506Q, and Prothrombin 20210A in Splanchnic Vein Thrombosis: Analysis of Individual Patient Data From Three Prospective Studies. PMID: 27194890 |
Ref: Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells. PMID: 29552126 Ref: Identification of chromatin-accessible domains in non-alcoholic steatohepatitis-derived hepatocellular carcinoma. PMID: 29603380 Ref: Functional Modulation of Gene Expression by Ultraconserved Long Non-coding RNA TUC338 during Growth of Human Hepatocellular Carcinoma. PMID: 29888750 Ref: Fibrinolytic System Changes in Liver Surgery: A Pilot Observational Study. PMID: 30255021 |