Primary Site >> Colorectal Cancer
Gene >> RALA
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Ref: The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. PMID: 15075335 |
Ref: Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1). PMID: 17483352 |
Ref: Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway. PMID: 20003375 |
Ref: Activation and involvement of Ral GTPases in colorectal cancer. PMID: 21199803 |
Ref: Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. PMID: 22247021 Ref: Differential involvement of RalA and RalB in colorectal cancer. PMID: 22790202 |
Ref: Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer. PMID: 22450745 Ref: In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. PMID: 23630290 Ref: Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras.GTP-effector interaction. PMID: 25034098 |
Ref: Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway. PMID: 24462916 |
Ref: RLIP76 blockade by siRNA inhibits proliferation, enhances apoptosis, and suppresses invasion in HT29 colon cancer cells. PMID: 25213293 Ref: Protein phosphatase 2A is essential to maintain active Wnt signaling and its Abeta tumor suppressor subunit is not expressed in colon cancer cells. PMID: 25252130 Ref: Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. PMID: 25788273 Ref: Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer. PMID: 26033452 |
Ref: EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer. PMID: 26283684 |
Ref: RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer. PMID: 29196555 Ref: Multi-panel assay of serum autoantibodies in colorectal cancer. PMID: 29691673 |