Primary Site >> Stomach Cancer

Gene >> RAC1

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Ref: Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e-cadherin in gastric cancers.
PMID: 11275980
Ref: Pathogenicity island-dependent activation of Rho GTPases Rac1 and Cdc42 in Helicobacter pylori infection.
PMID: 11401689
Ref: [Rac subfamily expression and activity in gastrointestinal cancer cell lines].
PMID: 14575565
Ref: Expression of seven main Rho family members in gastric carcinoma.
PMID: 14975755
Ref: Inhibition of endothelial cell proliferation by targeting Rac1 GTPase with small interference RNA in tumor cells.
PMID: 15303276
Ref: [Expressions and activities of Rho GTPases in hypoxia and its relationship with tumor angiogenesis].
PMID: 15555278
Ref: NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages.
PMID: 15561713
Ref: Nucleotide variants within the IQGAP1 gene in diffuse-type gastric cancers.
PMID: 15611933
Ref: Cell adhesion status-dependent histone acetylation is regulated through intracellular contractility-related signaling activities.
PMID: 15961394
Ref: Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.
PMID: 16275761
Ref: Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation.
PMID: 16395716
Ref: [The effect of calcyclin binding protein on gastric cancer cell proliferation].
PMID: 17313807
Ref: Helicobacter pylori CagA induces AGS cell elongation through a cell retraction defect that is independent of Cdc42, Rac1, and Arp2/3.
PMID: 17194805
Ref: Phosphorylation of ephrin-B1 regulates dissemination of gastric scirrhous carcinoma.
PMID: 17591954
Ref: Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.
PMID: 18246045
Ref: Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells.
PMID: 18247343
Ref: Reactive oxygen species regulate urokinase plasminogen activator expression and cell invasion via mitogen-activated protein kinase pathways after treatment with hepatocyte growth factor in stomach cancer cells.
PMID: 19497102
Ref: [The effect of Rac1 siRNA on the biological behaviors of gastrointestinal cancer cells].
PMID: 19764550
Ref: Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway.
PMID: 20307526
Ref: Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals.
PMID: 20600540
Ref: RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1.
PMID: 21537845
Ref: RhoA/ROCK signaling mediates plasticity of scirrhous gastric carcinoma motility.
PMID: 21667311
Ref: [Biological significance of relationship between nuclear localization of Rac1 and progression of gastric carcinoma].
PMID: 22340048
Ref: An anti-Wnt5a antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis.
PMID: 22101459
Ref: Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
PMID: 22337890
Ref: Backbone assignment and secondary structure of Rnd1, an unusual Rho family small GTPase.
PMID: 22618864
Ref: The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion.
PMID: 23242308
Ref: Expression of Rac1, HIF-1alpha, and VEGF in gastric carcinoma: correlation with angiogenesis and prognosis.
PMID: 23485997
Ref: Effects of Tiam 1 on invasive capacity of gastric cancer cells in vitro and underlying mechanisms.
PMID: 23534724
Ref: PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells.
PMID: 23613900
Ref: Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells.
PMID: 23799130
Ref: Reduced expression of Rho GDP dissociation inhibitor 2 mRNA is associated with lymph node metastasis in gastric carcinoma.
PMID: 24137348
Ref: Expression and significance of Rac1, Pak1 and Rock1 in gastric carcinoma.
PMID: 23298303
Ref: VEGF-C mediates RhoGDI2-induced gastric cancer cell metastasis and cisplatin resistance.
PMID: 24585459
Ref: Asporin activates coordinated invasion of scirrhous gastric cancer and cancer-associated fibroblasts.
PMID: 24441039
Ref: Rac1 is correlated with aggressiveness and a potential therapeutic target for gastric cancer.
PMID: 25585795
Ref: RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells.
PMID: 25901126
Ref: Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells.
PMID: 26171059
Ref: p120-catenin participates in the progress of gastric cancer through regulating the Rac1 and Pak1 signaling pathway.
PMID: 26324182
Ref: TIPE2 functions as a metastasis suppressor via negatively regulating beta-catenin through activating GSK3beta in gastric cancer.
PMID: 26530498
Ref: Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer.
PMID: 26871290
Ref: Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
PMID: 26987289
Ref: Rho GTPases: RAC1 polymorphisms affected platinum-based chemotherapy toxicity in lung cancer patients.
PMID: 27299748
Ref: Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies.
PMID: 27589842
Ref: Emerging roles of RAC1 in treating lung cancer patients.
PMID: 27790713
Ref: Rho GTPases: Anti- or pro-neoplastic targets?
PMID: 27991930
Ref: Traditional Chinese medicine Jianpi Bushen therapy suppresses the onset of pre-metastatic niche in a murine model of spontaneous lung metastasis.
PMID: 28012398
Ref: miR 1296-5p Inhibits the Migration and Invasion of Gastric Cancer Cells by Repressing ERBB2 Expression.
PMID: 28099468
Ref: Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway.
PMID: 28223821
Ref: Upregulated Vav2 in gastric cancer tissues promotes tumor invasion and metastasis.
PMID: 28459214
Ref: The clinical value of Vav3 in peripheral blood for predicting lymphatic metastasis of gastric cancer.
PMID: 28513273
Ref: MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells.
PMID: 28601080
Ref: Type II cGMPdependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells.
PMID: 28849123
Ref: miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis.
PMID: 29587866
Ref: Diallyl disulfide inhibits TGFbeta1induced upregulation of Rac1 and betacatenin in epithelialmesenchymal transition and tumor growth of gastric cancer.
PMID: 29620286
Ref: PIEZO1 functions as a potential oncogene by promoting cell proliferation and migration in gastric carcinogenesis.
PMID: 29683214
Ref: Inhibition of gastric cancer by local anesthetic bupivacaine through multiple mechanisms independent of sodium channel blockade.
PMID: 29684861
Ref: Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations.
PMID: 29859005
Ref: miR-124-3p acts as a potential marker and suppresses tumor growth in gastric cancer.
PMID: 30013778
Ref: Neogenin-1 Promotes Cell Proliferation, Motility, and Adhesion by Up-Regulation of Zinc Finger E-Box Binding Homeobox 1 Via Activating the Rac1/PI3K/AKT Pathway in Gastric Cancer Cells.
PMID: 30064133