Primary Site >> Stomach Cancer
Gene >> PTGS2
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Ref: Expression of cyclooxygenase-2 in human gastric carcinoma. PMID: 9102213 |
Ref: Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. PMID: 9696706 Ref: Effects of NSAIDs on proliferation of gastric cancer cells in vitro: possible implication of cyclooxygenase-2 in cancer development. PMID: 9872498 |
Ref: Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma. PMID: 10022645 Ref: Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. PMID: 10404093 Ref: 9th Seah Cheng Siang Memorial Lecture: gastric cancer--where are we now? PMID: 10672411 |
Ref: Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer. PMID: 10656441 Ref: Increased expression of cyclooxygenase-2 protein in human gastric carcinoma. PMID: 10690533 Ref: Selective inhibition of cyclooxygenase-2 enhances mitomycin-C-induced apoptosis. PMID: 10803922 Ref: Aberrant methylation of the Cyclooxygenase 2 CpG island in colorectal tumors. PMID: 10945606 Ref: Induction of apoptosis by JTE-522, a specific cyclooxygenase-2 inhibitor, in human gastric cancer cell lines. PMID: 11205258 |
Ref: Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer. PMID: 11161397 Ref: Clinicopathologic association of cyclooxygenase 1 and cyclooxygenase 2 expression in gastric adenocarcinoma. PMID: 11176123 Ref: Expression of cyclooxygenase-2 in human gastric adenomas and adenocarcinomas. PMID: 11223821 Ref: Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. PMID: 11310828 Ref: Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma. PMID: 11346869 Ref: Involvement of cyclooxygenase-2 in hyperplastic gastritis induced by Helicobacter pylori infection in C57BL/6 mice. PMID: 11380326 Ref: Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. PMID: 11389100 Ref: Inverse association between cyclooxygenase-2 overexpression and microsatellite instability in gastric cancer. PMID: 11403917 Ref: Expression of cyclooxygenase-2 in dysplasia of the stomach and in intestinal-type gastric adenocarcinoma. PMID: 11448905 Ref: Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression. PMID: 11601879 Ref: Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. PMID: 11686835 Ref: Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells. PMID: 11854904 |
Ref: Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. PMID: 11774276 Ref: Cyclooxygenase-2 expression during carcinogenesis in the human stomach. PMID: 11793368 Ref: Chemoprevention of gastrointestinal malignancies with nonsteroidal antiinflammatory drugs. PMID: 11920463 Ref: Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia. PMID: 11943946 Ref: Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer. PMID: 12037025 Ref: Increased expression of survivin in gastric cancer patients and in first degree relatives. PMID: 12085263 Ref: [Association between Helicobacter pylori cagA strain infection and expression of cyclooxygenase 2 in gastric carcinoma]. PMID: 12126507 Ref: Expression of Ku70 and Ku80 mediated by NF-kappa B and cyclooxygenase-2 is related to proliferation of human gastric cancer cells. PMID: 12324457 Ref: Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells. PMID: 12370807 Ref: [Antisense inhibition of cyclooxygenase-2 reduces malignant phenotype of gastric cancer cells]. PMID: 12421501 Ref: [Significance of COX-2, p53, proliferating cell nuclear antigen and nm23 expressions in gastric cancer and its behavior]. PMID: 12452062 Ref: [Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells]. PMID: 12452063 Ref: [Delayed rectifier K(+) channel regulated by cyclooxygenase-2 in human gastric cancer cell]. PMID: 12485493 Ref: Cyclooxygenase-2 expression is associated with well-differentiated and intestinal-type pathways in gastric carcinogenesis. PMID: 12592098 Ref: Expression of Cyclooxygenase-2 Protein in Gastric Carcinogenesis. PMID: 26680871 |
Ref: Association of cyclooxygenase-2 expression with Hp-cagA infection in gastric cancer. PMID: 12532440 Ref: Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma. PMID: 12532441 Ref: 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. PMID: 12584173 Ref: Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer. PMID: 12606945 Ref: Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells. PMID: 12674216 Ref: Correlation between expression of cyclooxygenase-2 and angiogenesis in human gastric adenocarcinoma. PMID: 12679908 Ref: Promoter hypermethylation of cyclooxygenase-2 in gastric carcinoma. PMID: 12684668 Ref: Expression of COX-2 in stomach cancers and its relation to their biological features. PMID: 12686777 Ref: Increased abundance of cyclooxygenase-2 correlates with vascular endothelial growth factor-A abundance and tumor angiogenesis in gastric cancer. PMID: 12767510 Ref: Effects of combined octreotide and aspirin on the growth of gastric cancer. PMID: 12781040 Ref: Cyclooxygenase-2 overexpression correlates with vascular endothelial growth factor expression and tumor angiogenesis in gastric cancer. PMID: 12811205 Ref: Effect of cyclooxygenase-2 inhibition on human Helicobacter pylori gastritis: mechanisms underlying gastrointestinal safety and implications for cancer chemoprevention. PMID: 12823157 Ref: Possible chemoresistance-related genes for gastric cancer detected by cDNA microarray. PMID: 12824904 Ref: Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma. PMID: 12854133 Ref: [The effects of selective cyclooxygenase-2 inhibitors on the growth of gastric adenocarcinoma]. PMID: 12910695 Ref: Combination chemotherapy with JTE-522, a novel selective cyclooxygenase-2 inhibitor, and cisplatin against gastric cancer cell lines in vitro and in vivo. PMID: 12929571 Ref: Diffuse and intestinal type gastric carcinomas differ in their expression of apoptosis related proteins. PMID: 12944556 Ref: Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines. PMID: 14520691 Ref: Cyclooxygenase-2 inhibition and gastric cancer. PMID: 14529406 Ref: Molecular mechanism of adaptive cytoprotection induced by ethanol in human gastric cells. PMID: 14530521 Ref: Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma. PMID: 14532971 Ref: Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas. PMID: 14550281 Ref: The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines. PMID: 14566822 Ref: Cyclooxygenase-2 and gastric carcinogenesis. PMID: 14616542 Ref: Influence of COX-2 inhibition by rofecoxib on serum and tumor progastrin and gastrin levels and expression of PPARgamma and apoptosis-related proteins in gastric cancer patients. PMID: 14627349 |
Ref: Chemoprevention of gastric cancer by celecoxib in rats. PMID: 14724149 Ref: Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. PMID: 14960510 Ref: A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells. PMID: 14962510 Ref: Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer. PMID: 15007244 Ref: Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. PMID: 15014433 Ref: Cyclooxygenase-2 expression correlates with angiogenesis and apoptosis in gastric cancer tissue. PMID: 15116331 Ref: [Role of cyclooxygenase-2 (COX-2) and peroxisome proliferator-activated receptor (PPAR) in gastric cancer]. PMID: 15156115 Ref: Sex differences in mucosal response to Helicobacter pylori infection in the stomach and variations in interleukin-8, COX-2 and trefoil factor family 1 gene expression. PMID: 15298601 Ref: Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2. PMID: 15319299 Ref: Enhanced inhibitive effects of combination of rofecoxib and octreotide on the growth of human gastric cancer. PMID: 15382074 Ref: Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation. PMID: 15456896 Ref: Concomitant overexpression of cyclooxygenase-2 in HER-2-positive on Smad4-reduced human gastric carcinomas is associated with a poor patient outcome. PMID: 15501972 Ref: Overexpression of cyclooxygenase-2 and tumor angiogenesis in human gastric cancer. PMID: 15532792 Ref: High microvascular density is correlated with high VEGF, iNOS and COX-2 expression in penetrating growth-type early gastric carcinomas. PMID: 15569052 Ref: Correlation between cyclooxygenase-2, proliferative activity, and mucin phenotype in human advanced gastric cancer. PMID: 15622477 Ref: [The role of cyclooxygenase-2 and vascular endothelial growth factor-C in lymphatic metastasis of gastric cancer]. PMID: 15634545 |
Ref: Relationship between expression and distribution of cyclooxygenase-2 and bcl-2 in human gastric adenocarcinoma. PMID: 15754411 Ref: Apoptosis of human gastric cancer SGC-7901 cells induced by mitomycin combined with sulindac. PMID: 15793875 Ref: Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. PMID: 15864753 Ref: Expression of peroxisome proliferator-activated receptor delta in human gastric cancer and its response to specific COX-2 inhibitor. PMID: 15890232 Ref: Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer. PMID: 15929174 Ref: Nicotine and gastric cancer. PMID: 16054988 Ref: Elevated cyclooxygenase-2 expression in patients with early gastric cancer in the gastric pylorus. PMID: 16082585 Ref: Expression of cyclooxygenase-2 in gastric cancer and its relation to liver metastasis and long-term prognosis. PMID: 16097070 Ref: Increased expression of cyclooxygenase-2 in first-degree relatives of gastric cancer patients. PMID: 16097073 Ref: Increased expression of interleukin-1alpha and cyclooxygenase-2 in human gastric cancer: a possible role in tumor progression. PMID: 16101131 Ref: Cyr61 induces gastric cancer cell motility/invasion via activation of the integrin/nuclear factor-kappaB/cyclooxygenase-2 signaling pathway. PMID: 16115920 Ref: [Relationship between cyclooxygenase- 2 expression and angiogenesis in patients with gastric cancer]. PMID: 16167259 Ref: [COX- 2 expression in gastric cancer and its relationship with lymphangiogenesis and lymph node metastasis]. PMID: 16167260 Ref: Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/microsomal prostaglandin E synthase-1 transgenic mice. PMID: 16230370 Ref: Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR. PMID: 16243808 Ref: Overexpression of cyclooxygenase-2 in gastric cancer correlates with the high abundance of vascular endothelial growth factor-C and lymphatic metastasis. PMID: 16260857 Ref: Expression of cyclooxygenase-2 and matrix metalloproteinase-9 in gastric carcinoma and its correlation with angiogenesis. PMID: 16314343 Ref: Nicotine induces cyclooxygenase-2 and vascular endothelial growth factor receptor-2 in association with tumor-associated invasion and angiogenesis in gastric cancer. PMID: 16317086 Ref: [Expression of cyclooxygenase-2, hMLH1 and hMSH2 proteins, and their relationship with microsatellite instability in gastric carcinoma]. PMID: 16438886 Ref: Aberrant methylation of cyclooxygenase-2 in breast cancer patients. PMID: 16507389 Ref: Cyclooxygenase-2 expression is associated with VEGF-C and lymph node metastases in gastric cancer patients. PMID: 16507394 Ref: Cyclooxygenase-2 inhibitors suppress angiogenesis and growth of gastric cancer xenografts. PMID: 16507395 |
Ref: Effects of COX-2 inhibitor on growth of human gastric cancer cells and its relation to hepatocyte growth factor. PMID: 16243430 Ref: Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice. PMID: 16254046 Ref: Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer. PMID: 16338068 Ref: Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells. PMID: 16371352 Ref: Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques. PMID: 16371738 Ref: Heparin increases human gastric carcinoma cell growth. PMID: 16475731 Ref: Low-dose aspirin affects the clinicopathological features of gastric cancer. PMID: 16554658 Ref: [Mechanisms of inhibiting proliferation and inducing apoptosis of human gastric cancer cell line SGC7901 by ursolic acid]. PMID: 16613675 Ref: Inhibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer cells. PMID: 16641552 Ref: [Effects of inhibition of cyclooxygenase-2 by RNA interference on proliferation and apoptosis of human gastric cancer cells: an experimental study with human gastric cancer cells and mice]. PMID: 16677508 Ref: [Genetic polymorphisms in the promoter region of cyclooxygenase-2 and their association with risk of gastric cancer]. PMID: 16733888 Ref: Effects of long-term rofecoxib on gastric intestinal metaplasia: results of a randomized controlled trial. PMID: 16899628 Ref: Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer. PMID: 16900533 Ref: Decreased xanthine oxidoreductase is a predictor of poor prognosis in early-stage gastric cancer. PMID: 16935971 Ref: The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach. PMID: 16938519 Ref: Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. PMID: 17030179 Ref: Expression of cyclooxygenase-2, p53 and Ki-67 in gastric cancer. PMID: 17043422 Ref: [Prophylactic effect of a selective COX-2 inhibitor celecoxib on carcinogen-induced gastric premalignant lesions in rats]. PMID: 17059761 Ref: [Expression of tissue microarray p53, p16 and cyclooxygenase-2 in gastric cancer]. PMID: 17074152 Ref: Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells. PMID: 17078003 Ref: Microvessel density is a prognostic marker of human gastric cancer. PMID: 17171787 Ref: [The effect of calcyclin binding protein on gastric cancer cell proliferation]. PMID: 17313807 Ref: Cyclooxygenase-2 expression in chronic gastritis and gastric carcinoma, correlation with prognostic parameters. PMID: 18301460 |
Ref: Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. PMID: 17003101 Ref: Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma. PMID: 17096355 Ref: Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. PMID: 17224647 Ref: Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability. PMID: 17374440 Ref: COX-2 expression in gastric cancer and its relationship with angiogenesis using tissue microarray. PMID: 17659693 Ref: Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clinicopathological characteristics in human gastric carcinoma. PMID: 17687613 Ref: [The potential role of Id1 in COX-2 mediated angiogenesis in gastric cancer]. PMID: 17785115 Ref: Clinical significance of prostaglandin E synthase expression in gastric cancer tissue. PMID: 17868774 Ref: Thinking in and out of the box when it comes to gastric cancer and cyclooxygenase-2. PMID: 17971580 Ref: Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer. PMID: 17971584 Ref: Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis. PMID: 17974958 Ref: Targeted inhibition of COX-2 expression by RNA interference suppresses tumor growth and potentiates chemosensitivity to cisplatin in human gastric cancer cells. PMID: 17982644 Ref: COX1 and COX2 polymorphisms and gastric cancer risk in a Polish population. PMID: 18214026 Ref: Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers. PMID: 18240541 Ref: [Study on inhibitory effects of c9, t11-conjugated linoleic acid on migration of human gastric carcinoma cell line via cyclooxygenase-2 pathway]. PMID: 18399127 |
Ref: DNA repair Ku proteins in gastric cancer cells and pancreatic acinar cells. PMID: 17031478 Ref: Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer. PMID: 17960625 Ref: Positive VEGF immunostaining independently predicts poor prognosis in curatively resected gastric cancer patients: results of a study assessing a panel of angiogenic markers. PMID: 17972143 Ref: Expression of cyclooxygenase-2 and vascular endothelial growth factor-C correlates with lymphangiogenesis and lymphatic invasion in human gastric cancer. PMID: 18068001 Ref: Expression of 15-PGDH is downregulated by COX-2 in gastric cancer. PMID: 18174234 Ref: Positive correlation of osteopontin, cyclooxygenase-2 and vascular endothelial growth factor in gastric cancer. PMID: 18181047 Ref: Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro. PMID: 18258354 Ref: Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. PMID: 18395088 Ref: The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pylori-induced urokinase-type plasminogen activator system in the gastric cancer cells. PMID: 18466392 Ref: Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis. PMID: 18521687 Ref: The effect of polysaccharide extracted from the marine alga Capsosiphon fulvescens on ethanol administration. PMID: 18524446 Ref: Constitutive hypophosphorylation of extracellular signal-regulated kinases-1/2 and down-regulation of c-Jun in human gastric adenocarcinoma. PMID: 18570890 Ref: Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice. PMID: 18611916 Ref: [The effect of siRNA on inhibiting cyclooxygenase-2 gene expression in gastric adenocarcinoma cell]. PMID: 18683800 Ref: Immunohistochemical expression of the cyclooxygenase-2 (COX-2) in gastric cancer. The correlations with the tumor angiogenesis and patients' survival. PMID: 18758643 Ref: Bile acid induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human gastric cancer cells. PMID: 18775915 Ref: Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. PMID: 18805435 Ref: Roles of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression and beta-catenin activation in gastric carcinogenesis in N-methyl-N-nitrosourea-treated K19-C2mE transgenic mice. PMID: 19018769 Ref: [Celecoxib induces apoptosis and inhibits angiogenesis in gastric cancer]. PMID: 19024521 Ref: Decreased expression of 15-hydroxyprostaglandin dehydrogenase in gastric carcinomas. PMID: 19108014 Ref: [Expression of cyclooxygenase-2 and urokinase plasminogen activator in gastric carcinoma and the clinical significance thereof]. PMID: 19159555 Ref: A polymorphism in the 3'-utr of cyclooxygenase-2 and the risk of gastric cancer. PMID: 21479450 |
Ref: Anticancer effect of celecoxib via COX-2 dependent and independent mechanisms in human gastric cancers cells. PMID: 18923901 Ref: Cyclooxygenase-2 is an independent prognostic factor in gastric carcinoma patients receiving adjuvant chemotherapy and is not associated with EBV infection. PMID: 19118057 Ref: Molecular basis of therapeutic approaches to gastric cancer. PMID: 19196394 Ref: Helicobacter pylori enhances cyclooxygenase 2 expression via p38MAPK/ATF-2 signaling pathway in MKN45 cells. PMID: 19201083 Ref: Association between color doppler vascularity index, angiogenesis-related molecules, and clinical outcomes in gastric cancer. PMID: 19418489 Ref: Effects of non-cytotoxic drugs on the growth of multidrug-resistance human gastric carcinoma cell line. PMID: 19426390 Ref: The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. PMID: 19491270 Ref: [Short-term preoperative treatment of celecoxib, a selective cyclooxygenase-2 inhibitor, on E-cadherin expression in gastric carcinoma tissues]. PMID: 19622294 Ref: Peroxisome proliferator-activated receptor delta and gastric cancer (Review). PMID: 19639188 Ref: Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China. PMID: 19661089 Ref: MBP-1 suppresses growth and metastasis of gastric cancer cells through COX-2. PMID: 19846662 Ref: Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines. PMID: 19940363 Ref: [Celecoxib inhibits gastric adenocarcinoma growth via inducing expression of human nonsteroidal anti-inflammatory drug activated gene]. PMID: 20067113 |
Ref: Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner. PMID: 19900843 Ref: Esophagogastric cancer: targeted agents. PMID: 20122806 Ref: COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer. PMID: 20237896 Ref: [Gastric carcinoma and chronic gastritis: epigenetic regulation of CDH1 (E-Cadherin), CDKN2A (p16INK4A), PTGS2 (COX-2) and EGFR genes through methylation]. PMID: 20353702 Ref: [Quantification of cyclooxygenase-2 methylation in gastric mucosa by denaturing high performance liquid chromatography assay]. PMID: 20388365 Ref: Dysregulation of cellular signaling in gastric cancer. PMID: 20488613 Ref: Anti-cancer activity of anti-p185HER-2 ricin A chain immunotoxin on gastric cancer cells. PMID: 20594254 Ref: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. PMID: 20651362 Ref: Preferential up-regulation of heparanase and cyclooxygenase-2 in carcinogenesis of Barrett's oesophagus and intestinal-type gastric carcinoma. PMID: 20653782 Ref: 15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human gastric cancer. PMID: 20699658 Ref: [Chinese herbal medicine Jianpi Jiedu Formula down-regulates the expression of vascular endothelial growth factor in human gastric cell line MKN45 induced by Helicobacter pylori by inhibiting cyclooxygenase-2]. PMID: 20939988 Ref: KITENIN is associated with tumor progression in human gastric cancer. PMID: 20944126 Ref: Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro. PMID: 20977754 Ref: The beta-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor kappaB signaling. PMID: 21042766 Ref: Cyclooxygenase-2 polymorphisms and susceptibility to gastric carcinoma: a meta-analysis. PMID: 21086572 Ref: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. PMID: 21194482 Ref: A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma. PMID: 21275453 |
Ref: Study on the association of COX-2 genetic polymorphisms with risk of gastric cancer in high incidence Hexi area of Gansu province in China. PMID: 20364406 Ref: Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians. PMID: 20473875 Ref: Prostaglandin E(2) signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. PMID: 21070778 Ref: NF-kappaB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. PMID: 21081469 Ref: Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis. PMID: 21205091 Ref: Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications. PMID: 21272377 Ref: Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells. PMID: 21494638 Ref: Arsenic trioxide inhibits invasion/migration in SGC-7901 cells by activating the reactive oxygen species-dependent cyclooxygenase-2/matrix metalloproteinase-2 pathway. PMID: 21540248 Ref: Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country. PMID: 21649724 Ref: Molecularly targeted therapies in unresectable-metastatic gastric cancer: a systematic review. PMID: 21676549 Ref: Gastric cancer: basic aspects. PMID: 21896084 Ref: Cyclooxygenase-2 and gastric cancer. PMID: 22002749 Ref: Involvement of nuclear factor kappaB (NF-kappaB) in the downregulation of cyclooxygenase-2 (COX-2) by genistein in gastric cancer cells. PMID: 22289529 Ref: Sinomenine inhibits proliferation of SGC-7901 gastric adenocarcinoma cells via suppression of cyclooxygenase-2 expression. PMID: 22848259 |
Ref: Vitamin D(3) upregulated protein 1 deficiency promotes N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric carcinogenesis in mice. PMID: 21917648 Ref: Notch2-induced COX-2 expression enhancing gastric cancer progression. PMID: 21976141 Ref: Inhibition of cyclooxygenase-2 causes regression of gastric adenomas in trefoil factor 1 deficient mice. PMID: 22034055 Ref: Prognostic significance of cyclooxygenase-2, epidermal growth factor receptor 1, and microvascular density in gastric cancer. PMID: 22048943 Ref: Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases. PMID: 22371637 Ref: A genetic variant in 3'-untranslated region of cyclooxygenases-2 gene is associated with risk of gastric cancer in a Chinese population. PMID: 22385256 Ref: Tumor interstitial fluid and gastric cancer metastasis: an experimental study to verify the hypothesis of "tumor-phlegm microenvironment". PMID: 22549391 Ref: The influence of transforming growth factor-alpha, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer. PMID: 22582975 Ref: Cyclooxygenase-2 polymorphisms and the risk of gastric cancer in various degrees of relationship in the Chinese Han population. PMID: 22740864 Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 Ref: Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells. PMID: 22941376 Ref: Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth. PMID: 23013439 Ref: Heterogeneity of COX-2 and multidrug resistance between primary tumors and regional lymph node metastases of gastric cancer. PMID: 23052170 Ref: Assessment of COX-2 expression presence and severity by immunohistochemical method in patients with chronic active gastritis and intestinal metaplasia. PMID: 23161322 |
Ref: The role of PGE2-associated inflammatory responses in gastric cancer development. PMID: 23053397 Ref: Effects of IL-1beta on the proliferation and apoptosis of gastric epithelial cells and acid secretion from isolated rabbit parietal cells. PMID: 23128938 Ref: Delivery of ursolic acid (UA) in polymeric nanoparticles effectively promotes the apoptosis of gastric cancer cells through enhanced inhibition of cyclooxygenase 2 (COX-2). PMID: 23194884 Ref: Reduced group IVA phospholipase A2 expression is associated with unfavorable outcome for patients with gastric cancer. PMID: 23307260 Ref: Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells. PMID: 23376640 Ref: Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid. PMID: 23577140 Ref: [Expressions of COX-2, PKC-alpha and miR-101 in gastric cancer and their correlations]. PMID: 23644120 Ref: COX-2 regulates E-cadherin expression through the NF-kappaB/Snail signaling pathway in gastric cancer. PMID: 23670240 Ref: [Effects of class I( phosphatidylinositol-3-kinases inhibitor on gastric cancer cell xenografts in nude mice]. PMID: 23696410 Ref: Cyclooxygenase-2 polymorphisms were associated with the risk of gastric cancer: evidence from a meta-analysis based on case-control studies. PMID: 23775011 Ref: CD44(+) gastric cancer cells with stemness properties are chemoradioresistant and highly invasive. PMID: 23833643 Ref: COX-2-765G>C polymorphism increases the risk of cancer: a meta-analysis. PMID: 24023834 Ref: COX-2, TFF1, and Src define better prognosis in young patients with gastric cancer. PMID: 24037722 Ref: Interaction between cyclooxygenase-2, Snail, and E-cadherin in gastric cancer cells. PMID: 24115825 Ref: Expression and significance of cyclooxygenase-2 mRNA in benign and malignant ascites. PMID: 24187465 Ref: Overexpression of miR-196b and HOXA10 characterize a poor-prognosis gastric cancer subtype. PMID: 24222951 Ref: Role of cyclooxygenase-2 in gastric cancer development and progression. PMID: 24259966 Ref: MicroRNA-143 suppresses gastric cancer cell growth and induces apoptosis by targeting COX-2. PMID: 24616567 |
Ref: Association of COX2 gene hypomethylation with intestinal type gastric cancer in samples of patients from northern Brazil. PMID: 24014049 Ref: Impact of non-steroidal anti-inflammatory drugs on gastrointestinal cancers: current state-of-the science. PMID: 24021750 Ref: Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer. PMID: 24176842 Ref: Cyclooxygenase-2 expression is associated with poor overall survival of patients with gastric cancer: a meta-analysis. PMID: 24178897 Ref: Antiinflammatory and antiproliferative effects of Rhus verniciflua Stokes in RAW264.7 cells. PMID: 24190230 Ref: Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products. PMID: 24233024 Ref: FOXP3 inhibits NF-kappaB activity and hence COX2 expression in gastric cancer cells. PMID: 24308961 Ref: Notch1 silencing inhibits proliferation and invasion in SGC7901 gastric cancer cells. PMID: 24469571 Ref: Effect of celecoxib plus standard chemotherapy on serum levels of vascular endothelial growth factor and cyclooxygenase-2 in patients with gastric cancer. PMID: 24649093 Ref: PLCepsilon1: a potential target of RNA interference therapy for gastric cancer. PMID: 24796667 Ref: Anti-helicobacter pylori effect of total alkaloids of sophora alopecuroides in vivo. PMID: 24985588 Ref: Helicobacter pylori promotes VEGF expression via the p38 MAPKmediated COX2PGE2 pathway in MKN45 cells. PMID: 25110109 Ref: Cyclooxygenase 2 in gastric carcinoma is expressed in doublecortin- and CaM kinase-like-1-positive tuft cells. PMID: 25228975 Ref: The mechanism of COX-2 regulating HERG channel in gastric cancer cells. PMID: 25246284 Ref: The inhibitory effect of pseudolaric acid B on gastric cancer and multidrug resistance via Cox-2/PKC-alpha/P-gp pathway. PMID: 25250794 Ref: The -765G>C polymorphism in the cyclooxygenase-2 gene and digestive system cancer: a meta-analysis. PMID: 25339021 Ref: COX-2 Inhibitors and Gastric Cancer. PMID: 25371669 Ref: Effect of celecoxib combined with chemotherapy drug on malignant biological behaviors of gastric cancer. PMID: 25550798 Ref: Inhibition of Glioblastoma Cell Growth In Vitro and In Vivo by Brucine, a Component of Chinese Medicine. PMID: 26629939 |
Ref: Pseudolaric acid B circumvents multidrug resistance phenotype in human gastric cancer SGC7901/ADR cells by downregulating Cox-2 and P-gp expression. PMID: 25077681 Ref: Inhibition of beta-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo. PMID: 25331984 Ref: Chloroquine inhibits MGC803 gastric cancer cell migration via the Toll-like receptor 9/nuclear factor kappa B signaling pathway. PMID: 25369757 Ref: Correlation of 15-prostagladin dehydrogenase expression with clinicopathological factors and survival rate in gastric adenocarcinoma. PMID: 25704623 Ref: Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. PMID: 25916550 Ref: Sensitivity of gastric cancer cells to chemotherapy drugs in elderly patients and its correlation with cyclooxygenase-2 expression. PMID: 25921160 Ref: Celecoxib enhanced the cytotoxic effect of cisplatin in drug-resistant human gastric cancer cells by inhibition of cyclooxygenase-2. PMID: 26407653 Ref: Paclitaxel combined with harmine inhibits the migration and invasion of gastric cancer cells through downregulation of cyclooxygenase-2 expression. PMID: 26622726 |
Ref: Osteopontin, E-cadherin, and beta-catenin expression as prognostic biomarkers in patients with radically resected gastric cancer. PMID: 25862567 Ref: Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry. PMID: 26391267 Ref: Tanshinone IIA decreases the migratory ability of AGS cells by decreasing the protein expression of matrix metalloproteinases, nuclear factor kappaB-p65 and cyclooxygenase-2. PMID: 26648518 Ref: Celecoxib enhanced the cytotoxic effect of cisplatin in chemo-resistant gastric cancer xenograft mouse models through a cyclooxygenase-2-dependent manner. PMID: 26879869 Ref: Alterations of Cyclooxygenase-2 Methylation Levels Before and After Intervention Trial to Prevent Gastric Cancer in a Chinese Population. PMID: 27020655 Ref: Gastric cancer cells inhibit natural killer cell proliferation and induce apoptosis via prostaglandin E2. PMID: 27057432 Ref: Effect of interleukin-1beta and tumor necrosis factor alpha gene silencing on mouse gastric cancer cell proliferation and migration. PMID: 27073517 Ref: Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways. PMID: 27079437 Ref: Helicobacter pylori promotes angiogenesis depending on Wnt/beta-catenin-mediated vascular endothelial growth factor via the cyclooxygenase-2 pathway in gastric cancer. PMID: 27198692 Ref: Clinical and prognosis relevance of COX-2 expression in Tunisian patients with primary gastric adenocarcinoma. PMID: 27314294 Ref: Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients. PMID: 27384994 Ref: Harmine combined with paclitaxel inhibits tumor proliferation and induces apoptosis through down-regulation of cyclooxygenase-2 expression in gastric cancer. PMID: 27446381 Ref: Prognostic significance of expression of cysteine-rich 61 and cyclooxygenase-2 in gastric cancer. PMID: 27457107 Ref: Anti-cancer activity and potential mechanism of a novel aspirin derivative. PMID: 27565221 Ref: Celecoxib exhibits an anti-gastric cancer effect by targeting focal adhesion and leukocyte transendothelial migration-associated genes. PMID: 27698798 |
Ref: Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells. PMID: 27377703 Ref: Association between COX-2 -1195G>A polymorphism and gastrointestinal cancer risk: A meta-analysis. PMID: 28405152 Ref: COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway. PMID: 28586004 Ref: Expressions of Ras Homolog Gene Family, Member A (RhoA) and Cyclooxygenase-2 (COX-2) Proteins in Early Gastric Cancer and Their Role in the Development of Gastric Cancer. PMID: 28624843 Ref: Prognostic and Predictive Value of p21-activated Kinase 6 Associated Support Vector Machine Classifier in Gastric Cancer Treated by 5-fluorouracil/Oxaliplatin Chemotherapy. PMID: 28687498 Ref: Store-operated Ca(2+) Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells. PMID: 29038542 Ref: Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice. PMID: 29081696 Ref: RIP140 and LCoR expression in gastrointestinal cancers. PMID: 29340045 Ref: Comprehensive evaluation of clinical efficacy and safety of celecoxib combined with chemotherapy in management of gastric cancer. PMID: 29390421 |
Ref: Expression profiles of Annexin A1, formylated peptide receptors and cyclooxigenase-2 in gastroesophageal inflammations and neoplasias. PMID: 29254791 Ref: Transcriptome profiling of cancer tissues in Chinese patients with gastric cancer by high-throughput sequencing. PMID: 29434905 Ref: MicroRNA-144 functions as a tumor suppressor in gastric cancer by targeting cyclooxygenase-2. PMID: 29456712 Ref: Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells. PMID: 29781036 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: The role of bile acids in cellular invasiveness of gastric cancer. PMID: 29942193 Ref: Correlation of COX-2 and MMP-13 expressions with gastric cancer and their effects on prognosis. PMID: 30003735 Ref: Quantitative analysis of COX-2 promoter methylation in gastric carcinoma. PMID: 30079321 |