Primary Site >> Colorectal Cancer
Gene >> PTGER2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: The role of cyclic AMP and oxygen intermediates in the inhibition of cellular immunity in cancer. PMID: 8917629 |
Ref: Nonsteroidal anti-inflammatory drugs may prevent colon cancer through suppression of hepatocyte growth factor expression. PMID: 10082276 |
Ref: Effect of prostaglandin E1 on vascular endothelial growth factor production by human macrophages and colon cancer cells. PMID: 10965822 |
Ref: Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. PMID: 11533709 |
Ref: Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2. PMID: 12837940 |
Ref: Expression pattern of epithelial cell adhesion molecule on normal and malignant colon tissues. PMID: 15637741 Ref: Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. PMID: 16293724 |
Ref: Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis. PMID: 16886605 Ref: Signal transduction cross-talk during colorectal tumorigenesis. PMID: 16998321 |
Ref: Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells. PMID: 17555711 Ref: The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. PMID: 17631291 |
Ref: Prostanoid receptor EP1 expression in breast cancer. PMID: 17906615 Ref: Dendritic cell infiltration pattern along the colorectal adenoma-carcinoma sequence. PMID: 18754318 Ref: Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells. PMID: 19055708 |
Ref: Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk. PMID: 20042636 Ref: Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia. PMID: 20100359 Ref: PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. PMID: 20200425 |
Ref: A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma. PMID: 22551900 Ref: HT-29 human colon cancer cell proliferation is regulated by cytosolic phospholipase A(2)alpha dependent PGE(2)via both PKA and PKB pathways. PMID: 22728329 |
Ref: Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the Colon Cancer Family Registry. PMID: 24908683 Ref: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells. PMID: 25096910 Ref: Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines. PMID: 25431425 |
Ref: Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth. PMID: 26018088 |
Ref: Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth. PMID: 26300003 Ref: Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue. PMID: 27548026 |
Ref: Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation. PMID: 28275297 Ref: Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells. PMID: 28587064 Ref: Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness. PMID: 28652251 Ref: Prostaglandin E2-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment. PMID: 29259703 |