Primary Site >> Colorectal Cancer

Gene >> PAWR

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Ref: Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells.
PMID: 10833474
Ref: Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer.
PMID: 11356199
Ref: Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.
PMID: 19729995
Ref: Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.
PMID: 20433755
Ref: The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
PMID: 21555373
Ref: The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.
PMID: 21910008
Ref: TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells.
PMID: 27830973
Ref: miR-107 Promotes Proliferation and Inhibits Apoptosis of Colon Cancer Cells by Targeting Prostate Apoptosis Response-4 (Par4).
PMID: 27938501
Ref: Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth.
PMID: 28500171
Ref: miR-17-3P regulates the proliferation and survival of colon cancer cells by targeting Par4.
PMID: 29115593