Primary Site >> Colorectal Cancer
Gene >> NCOR2
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Ref: 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways. PMID: 15798084 |
Ref: CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo. PMID: 16731764 Ref: CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo. PMID: 16891455 |
Ref: Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. PMID: 17190815 Ref: Aberrant cytoplasmic localization of N-CoR in colorectal tumors. PMID: 17630505 |
Ref: DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3. PMID: 18408752 Ref: HDAC4 promotes growth of colon cancer cells via repression of p21. PMID: 18632985 |
Ref: Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. PMID: 21624135 |
Ref: A truncated form of IKKalpha is responsible for specific nuclear IKK activity in colorectal cancer. PMID: 23041317 |
Ref: Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1alpha,25-dihydroxyvitamin D3-responsive genes. PMID: 22944139 |