Primary Site >> Colorectal Cancer
Gene >> MYD88
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Ref: Intracellular expression of toll-like receptor 4 in neuroblastoma cells and their unresponsiveness to lipopolysaccharide. PMID: 17156435 |
Ref: Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. PMID: 18538140 |
Ref: Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PMID: 19551144 Ref: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. PMID: 19722233 Ref: Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. PMID: 19732721 |
Ref: High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer. PMID: 20145615 Ref: Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8. PMID: 20515950 Ref: TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. PMID: 20526283 Ref: Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity. PMID: 20823152 |
Ref: The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models. PMID: 22218775 Ref: TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome. PMID: 22238604 Ref: Mutational and expressional analyses of MYD88 gene in common solid cancers. PMID: 23235763 |
Ref: Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells. PMID: 23184679 Ref: MyD88 in DNA repair and cancer cell resistance to genotoxic drugs. PMID: 23766530 Ref: Repressing DNA repair to enhance chemotherapy: targeting MyD88 in colon cancer. PMID: 23766531 Ref: Innate immunity gene polymorphisms and the risk of colorectal neoplasia. PMID: 23803696 Ref: TLR9 signaling in the tumor microenvironment initiates cancer recurrence after radiotherapy. PMID: 24154870 Ref: Functional TLR5 genetic variants affect human colorectal cancer survival. PMID: 24154872 |
Ref: Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis. PMID: 24412611 Ref: MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice. PMID: 24603458 Ref: Graphene oxide triggers toll-like receptors/autophagy responses in vitro and inhibits tumor growth in vivo. PMID: 24652749 Ref: Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer. PMID: 24887488 Ref: Cell-intrinsic TLR2/MyD88 pathway in breast and colon cancer. PMID: 25457615 Ref: Upregulation of TLRs and IL-6 as a marker in human colorectal cancer. PMID: 25547486 |
Ref: Apple polysaccharide reduces NF-Kb mediated colitis-associated colon carcinogenesis. PMID: 25412264 Ref: Diverse roles of STING-dependent signaling on the development of cancer. PMID: 25639870 Ref: Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. PMID: 25907800 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: Roles of TLR/MyD88/MAPK/NF-kappaB Signaling Pathways in the Regulation of Phagocytosis and Proinflammatory Cytokine Expression in Response to E. faecalis Infection. PMID: 26317438 |
Ref: Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. PMID: 26712311 Ref: Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc(+/1638N) Mice: Comparisons and Contrasts. PMID: 27698916 |
Ref: Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-kappaB, and Up-regulating Expression of MicroRNA-21. PMID: 27876571 Ref: Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin. PMID: 28179508 Ref: Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. PMID: 28300841 Ref: Resistin causes G1 arrest in colon cancer cells through upregulation of SOCS3. PMID: 28417458 Ref: Multi-factorial modulation of colorectal carcinoma cells motility - partial coordination by the tetraspanin Co-029/tspan8. PMID: 28418857 Ref: Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma. PMID: 28533893 Ref: Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy. PMID: 28753429 Ref: Andrographolide suppresses proliferation of human colon cancer SW620 cells through the TLR4/NF-kappaB/MMP-9 signaling pathway. PMID: 28943944 Ref: Leukotriene B4-receptor-1 mediated host response shapes gut microbiota and controls colon tumor progression. PMID: 29209564 |
Ref: Loss of BMI-1 dampens migration and EMT of colorectal cancer in inflammatory microenvironment through TLR4/MD-2/MyD88-mediated NF-kappaB signaling. PMID: 28815730 Ref: Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. PMID: 29696632 Ref: Contribution of drugs acting on the TLRs/MyD88 signaling pathway on colitis-associated cancer. PMID: 30001768 Ref: Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis. PMID: 30063920 Ref: Dual functional roles of the MyD88 signaling in colorectal cancer development. PMID: 30086464 Ref: Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy. PMID: 30221070 Ref: Cell-free DNA derived from cancer cells facilitates tumor malignancy through Toll-like receptor 9 signaling-triggered interleukin-8 secretion in colorectal cancer. PMID: 30239551 |