Primary Site >> Esophagus Cancer
Gene >> MTOR
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Ref: Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells. PMID: 15718251 |
Ref: Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. PMID: 17273761 |
Ref: Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. PMID: 18413730 Ref: TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. PMID: 19020730 |
Ref: Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. PMID: 19164214 |
Ref: RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer. PMID: 20204306 Ref: Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma. PMID: 20339946 |
Ref: The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. PMID: 21467840 |
Ref: The crosstalk of mTOR/S6K1 and Hedgehog pathways. PMID: 22439934 Ref: Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. PMID: 22992618 |
Ref: Clinicopathologic significance and function of mammalian target of rapamycin activation in esophageal squamous cell carcinoma. PMID: 22944293 Ref: Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice. PMID: 23291985 Ref: Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation. PMID: 23555162 Ref: Inflammation and ovarian cancer--current views. PMID: 23700863 Ref: Emerging tyrosine kinase inhibitors for esophageal cancer. PMID: 23725567 Ref: Metformin inhibits esophagus cancer proliferation through upregulation of USP7. PMID: 24335168 |
Ref: Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy. PMID: 24438628 Ref: Targeted therapies in metastatic esophageal cancer: advances over the past decade. PMID: 24582516 Ref: New directions in perioperative management of locally advanced esophagogastric cancer. PMID: 24857100 Ref: Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer. PMID: 24859412 Ref: Inhibition of mammalian target of rapamycin by rapamycin increases the radiosensitivity of esophageal carcinoma Eca109 cells. PMID: 25009644 Ref: MicroRNA-100 promotes migration and invasion through mammalian target of rapamycin in esophageal squamous cell carcinoma. PMID: 25109390 |
Ref: Metformin enhances radiation response of ECa109 cells through activation of ATM and AMPK. PMID: 25661368 Ref: Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. PMID: 25733817 Ref: Immunohistochemical and molecular analysis of PI3K/AKT/mTOR pathway in esophageal carcinoma. PMID: 25912437 Ref: Phase II trial of everolimus in patients with refractory metastatic adenocarcinoma of the esophagus, gastroesophageal junction and stomach: possible role for predictive biomarkers. PMID: 25969130 Ref: The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121. PMID: 26235881 Ref: Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation. PMID: 26378019 Ref: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells. PMID: 26498695 Ref: Mutant HRAS as novel target for MEK and mTOR inhibitors. PMID: 26544513 |
Ref: Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway. PMID: 26318432 Ref: Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells. PMID: 27357907 Ref: Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma. PMID: 27384996 Ref: Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo. PMID: 27453171 Ref: Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation. PMID: 27564102 Ref: beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro. PMID: 27586268 Ref: Gene-gene interactions in gastrointestinal cancer susceptibility. PMID: 27588484 |
Ref: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. PMID: 27857021 Ref: The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKalpha/mTOR pathway in vitro and in vivo. PMID: 28052030 Ref: RICTOR expression in esophageal squamous cell carcinoma and its clinical significance. PMID: 28132115 Ref: Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway. PMID: 28463955 Ref: miR-195 Regulates Proliferation and Apoptosis through Inhibiting the mTOR/p70s6k Signaling Pathway by Targeting HMGA2 in Esophageal Carcinoma Cells. PMID: 28487599 Ref: MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway. PMID: 28498460 Ref: Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway. PMID: 28631572 Ref: FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. PMID: 28857247 Ref: Simultaneous targeting PI3K and PERK pathways promotes cell death and improves the clinical prognosis in esophageal squamous carcinoma. PMID: 28867195 Ref: [Checkpoint Inhibitors in the Treatment of Upper Gastrointestinal Tract Tumors]. PMID: 29239193 |
Ref: Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo. PMID: 29290767 Ref: Vitexin induces G2/Mphase arrest and apoptosis via Akt/mTOR signaling pathway in human glioblastoma cells. PMID: 29328424 Ref: Serum-based six-miRNA signature as a potential marker for EC diagnosis: Comparison with TCGA miRNAseq dataset and identification of miRNA-mRNA target pairs by integrated analysis of TCGA miRNAseq and RNAseq datasets. PMID: 29380534 Ref: The Expression and Prognostic Impact of the PI3K/AKT/mTOR Signaling Pathway in Advanced Esophageal Squamous Cell Carcinoma. PMID: 29463194 Ref: Bufalin induces apoptosis in human esophageal carcinoma ECA109 cells by inhibiting the activation of the mTOR/p70S6K pathway. PMID: 29805658 Ref: Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways. PMID: 30035335 Ref: Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways. PMID: 30050135 Ref: TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway. PMID: 30098109 Ref: Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy. PMID: 30174840 Ref: Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. PMID: 30229997 Ref: Long Non-Coding RNA (lncRNA) Growth Arrest Specific 5 (GAS5) Suppresses Esophageal Squamous Cell Carcinoma Cell Proliferation and Migration by Inactivating Phosphatidylinositol 3-kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. PMID: 30368517 |