Primary Site >> Stomach Cancer
Gene >> MTHFR
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Ref: Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study. PMID: 11494235 |
Ref: [Polymorphisms of methylenetetrahydrofolate reductase C677T and the risk of stomach cancer]. PMID: 12411076 |
Ref: Pharmacogenetics of stomach cancer. PMID: 12914384 Ref: [Interactions between lifestyle, methylanetetrahydrofolate reductase gene and polymorphisms in thymidylate synthase gene with risk of stomach cancer]. PMID: 12975018 |
Ref: [A case-control study on the relationship between methyl-tetra-hydrofolic acid reductase 677 gene polymorphism and the risk of stomach cancer]. PMID: 15231125 Ref: Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking. PMID: 15244514 Ref: [Relationship of methylenetetrahydrofolate reductase C677T polymorphism and chemosensitivity to 5-fluorouracil in gastric carcinoma]. PMID: 15301724 Ref: [Polymorphism of methylenetetrahydrofolate reductase and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy]. PMID: 15769364 |
Ref: Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: a case-control analysis in China. PMID: 15643524 Ref: [Clinical significance of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in Korean patients with gastric cancer]. PMID: 16030402 Ref: Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population. PMID: 16158971 Ref: [The relationship between methylenetetrahydrofolate reductase gene polymorphism and microsatellite instability in gastric cancer]. PMID: 16536307 |
Ref: Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population. PMID: 16094648 Ref: Methylenetetrahydrofolate reductase 677C>T polymorphism and gastric cancer susceptibility in Mexico. PMID: 16359859 Ref: Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy. PMID: 16622263 Ref: Association of methylenetetrahydrofolate reductase (MTHFR) polymorphisms with genetic susceptibility to gastric cancer: a meta-analysis. PMID: 16758123 Ref: Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia. PMID: 16886608 Ref: The thymidylate synthase tandem repeat promoter polymorphism: A predictor for tumor-related survival in neoadjuvant treated locally advanced gastric cancer. PMID: 16929515 Ref: Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis. PMID: 17030196 Ref: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract. PMID: 17163161 Ref: Folate levels in mucosal tissue but not methylenetetrahydrofolate reductase polymorphisms are associated with gastric carcinogenesis. PMID: 17171786 |
Ref: Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer. PMID: 16927418 Ref: Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer. PMID: 17208363 Ref: Genetic polymorphisms in folate metabolism and the risk of stomach cancer. PMID: 17220339 Ref: Polymorphisms of MTHFD, plasma homocysteine levels, and risk of gastric cancer in a high-risk Chinese population. PMID: 17438114 Ref: Polymorphisms of 5,10-methylenetetralydrofolate reductase (MTHFR), fruit and vegetable intake, and the risk of stomach cancer. PMID: 17438654 Ref: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract. PMID: 17607914 Ref: Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population. PMID: 17972183 Ref: The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition. PMID: 18006931 Ref: Application of microarray-based method for methylenetetrahydrofolate reductase (MTHFR) polymorphisms in the risk of gastric carcinoma in east China population. PMID: 18019157 Ref: [C677T polymorphism of the MTHFR gene and the risk of developing distal gastric cancer in a Mexican population]. PMID: 18595323 |
Ref: Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review. PMID: 18162478 Ref: Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer. PMID: 18231104 Ref: Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis. PMID: 18340404 Ref: Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: an in vitro study. PMID: 18486501 Ref: Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. PMID: 18505952 Ref: Methylenetetrahydrofolate reductase polymorphisms and susceptibility to gastric cancer in Chinese populations: a meta-analysis. PMID: 18714187 Ref: A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk. PMID: 19506726 |
Ref: The polymorphisms of TS and MTHFR predict survival of gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy in Chinese population. PMID: 18704422 Ref: Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft internistische onkologie. PMID: 19332728 Ref: Analysis and estimates of the attributable risk for environmental and genetic risk factors in gastric cancer in a Chinese population. PMID: 19492240 Ref: MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis. PMID: 19521764 |
Ref: Dietary folate and vitamin B12 intake before diagnosis decreases gastric cancer mortality risk among susceptible MTHFR 677TT carriers. PMID: 19577428 Ref: Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition. PMID: 20056620 Ref: MTHFR polymorphisms in gastric cancer and in first-degree relatives of patients with gastric cancer. PMID: 20237899 Ref: BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin. PMID: 20331623 Ref: MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: a meta-analysis. PMID: 20409583 Ref: Folate intake along with genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase in patients with advanced gastric cancer. PMID: 20447923 Ref: Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer: a meta-analysis. PMID: 20470942 Ref: Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population. PMID: 20504332 Ref: A phase I/II and pharmacogenomic study of pemetrexed and cisplatin in patients with unresectable, advanced gastric carcinoma. PMID: 20634689 Ref: Genetic polymorphisms associated with 5-Fluorouracil-induced neurotoxicity. PMID: 20714149 Ref: MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection. PMID: 20957490 |
Ref: Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls. PMID: 20473868 Ref: DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy. PMID: 21347786 Ref: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). PMID: 21831520 |
Ref: Polymorphisms in ERCC1, GSTs, TS and MTHFR predict clinical outcomes of gastric cancer patients treated with platinum/5-Fu-based chemotherapy: a systematic review. PMID: 23020798 Ref: Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans. PMID: 23166529 Ref: Impact of methylenetetrahydrofolate reductase C677T polymorphism on the risk of gastric cancer and its interaction with Helicobacter pylori infection. PMID: 23183616 |
Ref: Polymorphism of TS 3'-UTR predicts survival of Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel. PMID: 23263912 Ref: Analysis of the methylation patterns of the p16 INK4A, p15 INK4B, and APC genes in gastric adenocarcinoma patients from a Brazilian population. PMID: 23504555 Ref: Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer. PMID: 23534741 Ref: Relationship between glutathione S-transferase P1 (GSTP1), X-ray repair cross complementing group 1 (XRCC1) and 5,10-methylenetetrahydrofolate reductase (5,10-MTHFR) gene polymorphisms and response to chemotherapy in advanced gastric cancer. PMID: 23774147 Ref: Aberrant DNA methylation of P16, MGMT, hMLH1 and hMSH2 genes in combination with the MTHFR C677T genetic polymorphism in gastric cancer. PMID: 23803092 Ref: Decrease in gastric cancer susceptibility by MTHFR C677T polymorphism in Ardabil Province, Iran. PMID: 23934457 Ref: Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer. PMID: 24550949 |
Ref: The polymorphism of methylenetetrahydrofolate reductase C677T but not A1298C contributes to gastric cancer. PMID: 23897558 Ref: MTHFR C677T polymorphism contributes to the risk for gastric cancer. PMID: 24122207 Ref: A retrospective comparative exploratory study on two methylentetrahydrofolate reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patient PMID: 24490800 Ref: Susceptibility to Helicobacter pylori infection: results of an epidemiological investigation among gastric cancer patients. PMID: 24526578 Ref: Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site. PMID: 24615072 Ref: Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer. PMID: 24737431 Ref: The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and tumor risk: evidence from 134 case-control studies. PMID: 24744129 Ref: Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility. PMID: 25170232 Ref: Screening of susceptibility genes and multi-gene risk analysis in gastric cancer. PMID: 25245011 Ref: Polymorphism of methylenetetrahydrofolate reductase gene is associated with response to fluorouracil-based chemotherapy in Chinese patients with gastric cancer. PMID: 25316230 Ref: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. PMID: 25337902 |
Ref: Polymorphism in one-carbon metabolism pathway affects survival of gastric cancer patients: Large and comprehensive study. PMID: 25840420 Ref: A Functional Variant at the miR-214 Binding Site in the Methylenetetrahydrofolatereductase Gene Alters Susceptibility to Gastric Cancer in a Chinese Han Population. PMID: 25998065 Ref: Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies. PMID: 26081619 Ref: Thymidylate synthase and methylenetetrahy-drofolate reductase gene polymorphisms and gastric cancer susceptibility in a population of Northern Brazil. PMID: 26345936 Ref: MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports. PMID: 26456456 Ref: Association between the MTHFR C677T polymorphism and gastric cancer susceptibility: A meta-analysis of 5,757 cases and 8,501 controls. PMID: 26622644 |
Ref: Influences of ERCC1, ERCC2, XRCC1, GSTP1, GSTT1, and MTHFR polymorphisms on clinical outcomes in gastric cancer patients treated with EOF chemotherapy. PMID: 26314858 Ref: Dietary folate, one-carbon metabolism-related genes, and gastric cancer risk in Korea. PMID: 26833750 Ref: Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine, followed by maintenance with capecitabine and bevacizumab, as first-line treatment of patients with advanced HER2-negative gastric cancer: A multicenter phase 2 study. PMID: 26970343 Ref: Evaluation of an Association of Blood Homocysteine Levels With Gastric Cancer Risk From 27 Case-Control Studies. PMID: 27196483 Ref: The effects of genomic polymorphisms in one-carbon metabolism pathways on survival of gastric cancer patients received fluorouracil-based adjuvant therapy. PMID: 27456431 Ref: ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients. PMID: 27487151 Ref: Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer. PMID: 27823653 |
Ref: Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies. PMID: 27995989 |
Ref: A Meta-Analysis: Methylenetetrahydrofolate Reductase C677T Polymorphism in Gastric Cancer Patients Treated with 5-Fu Based Chemotherapy Predicts Serious Hematologic Toxicity but Not Prognosis. PMID: 29581785 |