Primary Site >> Biliary tract Cancer
Gene >> MMP2
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Ref: Expression pattern of matrix metalloproteinases in human liver. PMID: 7632822 |
Ref: Expression of collagenase (MMP2), stromelysin (MMP3) and tissue inhibitor of the metalloproteinases (TIMP1) in pancreatic and ampullary disease. PMID: 8611434 Ref: Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors. PMID: 8675149 |
Ref: Hepatocyte growth factor stimulates the invasion of gallbladder carcinoma cell lines in vitro. PMID: 9502079 |
Ref: Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance. PMID: 12439941 |
Ref: Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma. PMID: 14687144 Ref: Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma. PMID: 15213623 Ref: [The in vitro effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cells and its mechanism]. PMID: 15312360 Ref: The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study. PMID: 15567754 Ref: Immunohistochemical expression of matrix metalloproteinases in bile duct cancer tissue. PMID: 15682828 Ref: A MEK inhibitor (U0126) markedly inhibits direct liver invasion of orthotopically inoculated human gallbladder cancer cells in nude mice. PMID: 15743030 |
Ref: Effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cells. PMID: 15832413 |
Ref: [Anti-tumor mechanism of norcantharidin for the implanted tumors of human gallbladder carcinoma in nude mice in vivo]. PMID: 16784656 |
Ref: Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis. PMID: 18227728 Ref: Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts. PMID: 18329694 Ref: The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters. PMID: 18630474 |
Ref: Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry. PMID: 18665467 Ref: The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression PMID: 19330734 Ref: Fascin is involved in tumor necrosis factor-alpha-dependent production of MMP9 in cholangiocarcinoma. PMID: 19721413 |
Ref: Expression of matrix metalloproteinase 2 and extracellular matrix metalloproteinase inducer are unfavorable postoperative prognostic factors in intrahepatic cholangiocarcinoma. PMID: 19629755 Ref: Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion. PMID: 20135719 Ref: Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. PMID: 20545696 Ref: Expression of LAPTM4B in gallbladder carcinoma cells: the role in invasive potential. PMID: 20583413 |
Ref: Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases. PMID: 21076843 |
Ref: Establishment and characterization of a cell line, EH-GB2, derived from hepatic metastasis of gallbladder cancer. PMID: 22134783 Ref: Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer. PMID: 22621753 Ref: Cepharanthine suppresses metastatic potential of human cholangiocarcinoma cell lines. PMID: 23480757 Ref: TNP-470, a methionine aminopeptidase-2 inhibitor, inhibits cell proliferation, migration and invasion of human cholangiocarcinoma cells in vitro. PMID: 23480758 |
Ref: Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma. PMID: 22875246 Ref: Prognostic significance of Capn4 overexpression in intrahepatic cholangiocarcinoma. PMID: 23349941 Ref: Characterization of two novel cell lines with distinct heterogeneity derived from a single human bile duct carcinoma. PMID: 23382894 Ref: Contribution of the PI3K/MMPs/Ln-5gamma2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas. PMID: 23588386 Ref: Annexin A1: A new immunohistological marker of cholangiocarcinoma. PMID: 23674846 Ref: Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis. PMID: 23919841 Ref: miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells. PMID: 24147037 |
Ref: Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer. PMID: 24438533 Ref: Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5gamma2 signaling pathway. PMID: 24628713 Ref: A multigenic approach to evaluate genetic variants of PLCE1, LXRs, MMPs, TIMP, and CYP genes in gallbladder cancer predisposition. PMID: 24863943 |
Ref: Norcantharidin enhances TIMP2 antivasculogenic mimicry activity for human gallbladder cancers through downregulating MMP2 and MT1MMP. PMID: 25405519 Ref: Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma. PMID: 25623530 Ref: Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-kappaB-mediated survival signaling pathways in human gallbladder cancer cells. PMID: 25633045 Ref: Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44nu is an indicator for recurrence in advanced cancer. PMID: 26572077 |
Ref: SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma. PMID: 26490986 Ref: Knockdown of RHOC by shRNA suppresses invasion and migration of cholangiocellular carcinoma cells via inhibition of MMP2, MMP3, MMP9 and epithelial-mesenchymal transition. PMID: 27108649 Ref: SHP2 and UGP2 are Biomarkers for Progression and Poor Prognosis of Gallbladder Cancer. PMID: 27389087 |
Ref: DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer. PMID: 28129656 Ref: Tropomyosin-related kinase B mediated signaling contributes to the induction of malignant phenotype of gallbladder cancer. PMID: 28423707 Ref: Inhibitory effect of norcantharidin on melanoma tumor growth and vasculogenic mimicry by suppressing MMP-2 expression. PMID: 28454306 Ref: 14-3-3sigma downregulation suppresses ICC metastasis via impairing migration, invasion, and anoikis resistance of ICC cells. PMID: 28482619 Ref: Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in Cholangiocarcinoma. PMID: 28535506 Ref: Wip1 is associated with tumorigenity and metastasis through MMP-2 in human intrahepatic cholangiocarcinoma. PMID: 28915621 Ref: Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma. PMID: 29404445 |
Ref: Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway. PMID: 29170841 Ref: Role of cantharidin in the activation of IKKalpha/IkappaBalpha/NFkappaB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines. PMID: 29620225 Ref: Alpha-L-Fucosidase Serves as a Prognostic Indicator for Intrahepatic Cholangiocarcinoma and Inhibits Its Invasion Capacity. PMID: 29682557 Ref: Knockdown of TRIM31 suppresses proliferation and invasion of gallbladder cancer cells by down-regulating MMP2/9 through the PI3K/Akt signaling pathway. PMID: 29864908 Ref: Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells. PMID: 30001777 Ref: Inhibiting the proliferation and metastasis of hilar cholangiocarcinoma cells by blocking the expression of vascular endothelial growth factor with small interfering RNA. PMID: 30008874 |