Primary Site >> Stomach Cancer

Gene >> MIEN1

  • 2003
  • 2004
  • 2015
  • 2017
Ref: MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
PMID: 12739007
Ref: Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon.
PMID: 15010812
Ref: Detection of novel and potentially actionable anaplastic lymphoma kinase (ALK) rearrangement in colorectal adenocarcinoma by immunohistochemistry screening.
PMID: 26172300
Ref: Genes co-amplified with ERBB2 or MET as novel potential cancer-promoting genes in gastric cancer.
PMID: 29190909