Primary Site >> Biliary tract Cancer
Gene >> MCL1
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Ref: COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells. PMID: 11870367 Ref: Pk11195, a mitochondrial benzodiazepine receptor antagonist, reduces apoptosis threshold in Bcl-X(L) and Mcl-1 expressing human cholangiocarcinoma cells. PMID: 12235080 |
Ref: Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. PMID: 15150106 Ref: Imatinib mesylate induces apoptosis in human cholangiocarcinoma cells. PMID: 15566522 |
Ref: Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. PMID: 16317687 |
Ref: Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes. PMID: 16469407 |
Ref: Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. PMID: 17241887 |
Ref: BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis. PMID: 18723481 |
Ref: The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. PMID: 19070389 Ref: Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. PMID: 19821497 |
Ref: Prognostic assessment of three single-nucleotide polymorphisms (GNB3 825C>T, BCL2-938C>A, MCL1-386C>G) in extrahepatic cholangiocarcinoma. PMID: 19968497 |
Ref: The BH3-mimetic ABT-737 targets the apoptotic machinery in cholangiocarcinoma cell lines resulting in synergistic interactions with zoledronic acid. PMID: 20473610 |
Ref: New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. PMID: 24563076 Ref: Expressions of farnesoid X receptor and myeloid cell leukemia sequence 1 protein are associated with poor prognosis in patients with gallbladder cancer. PMID: 25043081 Ref: Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PMID: 25536104 |
Ref: Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins. PMID: 25125499 Ref: ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics. PMID: 25936772 Ref: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway. PMID: 26592508 |
Ref: The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine. PMID: 26870236 Ref: Anoikis-resistant cholangiocarcinoma cells display aggressive characteristics and increase STAT3 activation. PMID: 27107220 Ref: The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer. PMID: 27420766 |
Ref: Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma. PMID: 29408314 |