Primary Site >> Esophagus Cancer
Gene >> MAPK3
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Ref: Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent. PMID: 11297525 |
Ref: Enhancement of peripheral benzodiazepine receptor ligand-induced apoptosis and cell cycle arrest of esophageal cancer cells by simultaneous inhibition of MAPK/ERK kinase. PMID: 15081869 Ref: The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. PMID: 15375172 |
Ref: Induction of cyclooxygenase-2 by benzo[a]pyrene diol epoxide through inhibition of retinoic acid receptor-beta 2 expression. PMID: 16170369 |
Ref: Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer. PMID: 16217753 Ref: Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model. PMID: 16488438 Ref: A growth-related oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal cancer. PMID: 16540656 Ref: RRIG1 mediates effects of retinoic acid receptor beta2 on tumor cell growth and gene expression through binding to and inhibition of RhoA. PMID: 16849557 |
Ref: Sphingosine kinases and sphingosine-1-phosphate are critical for transforming growth factor beta-induced extracellular signal-regulated kinase 1 and 2 activation and promotion of migration and invasion of esophageal cancer cells. PMID: 18426913 Ref: Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation via beta-adrenoceptor-dependent transactivation of extracellular signal-regulated kinase/cyclooxygenase-2 pathway. PMID: 18452159 |
Ref: Sp1 and AP-1 regulate expression of the human gene VIL2 in esophageal carcinoma cells. PMID: 19164283 Ref: Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. PMID: 19534809 |
Ref: Benzo[a]pyrene diol epoxide suppresses retinoic acid receptor-beta2 expression by recruiting DNA (cytosine-5-)-methyltransferase 3A. PMID: 20426865 Ref: Specificity protein 1 regulates fascin expression in esophageal squamous cell carcinoma as the result of the epidermal growth factor/extracellular signal-regulated kinase signaling pathway activation. PMID: 20502940 Ref: Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells. PMID: 21220916 |
Ref: The expression and activation of ERK/MAPK pathway in human esophageal cancer cell line EC9706. PMID: 20464500 Ref: A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma. PMID: 21707510 Ref: [Expression of ERK1/2 MAPK signaling transduction pathway in esophageal cancers in Kazakh patients]. PMID: 21875481 |
Ref: Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin. PMID: 22253518 Ref: Gene silencing of beta-catenin by RNAi inhibits proliferation of human esophageal cancer cells by inducing G0/G1 cell cycle arrest. PMID: 22938416 Ref: Coxsackievirus and adenovirus receptor promotes antitumor activity of oncolytic adenovirus H101 in esophageal cancer. PMID: 22992863 |
Ref: Raf kinase inhibitor protein inhibits esophageal cancer cell invasion through downregulation of matrix metalloproteinase expression. PMID: 23674108 Ref: Comparable molecular alterations in 4-nitroquinoline 1-oxide-induced oral and esophageal cancer in mice and in human esophageal cancer, associated with poor prognosis of patients. PMID: 23812217 Ref: PTP1B contributes to calreticulin-induced metastatic phenotypes in esophageal squamous cell carcinoma. PMID: 23814025 Ref: Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression. PMID: 24130695 |
Ref: ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. PMID: 25091467 Ref: [Expressions of Dab2 and ERK1 in esophageal carcinoma tissues and their clinical significance]. PMID: 25142995 Ref: Antitumor effects and molecular mechanisms of figitumumab, a humanized monoclonal antibody to IGF-1 receptor, in esophageal carcinoma. PMID: 25358597 Ref: Aquaporin-8 mediates human esophageal cancer Eca-109 cell migration via the EGFR-Erk1/2 pathway. PMID: 25550802 |
Ref: Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells. PMID: 25333998 Ref: PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer. PMID: 25617799 |
Ref: Effect of recombinant human endostatin onradiotherapy for esophagus cancer. PMID: 26851794 Ref: Silencing of CXCR2 and CXCR7 protects against esophageal cancer. PMID: 27648130 Ref: Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells. PMID: 27906434 |
Ref: Up-Regulation of MicroRNA-133a Inhibits the MEK/ERK Signaling Pathway to Promote Cell Apoptosis and Enhance Radio-Sensitivity by Targeting EGFR in Esophageal Cancer In Vivo and In Vitro. PMID: 27933650 Ref: Stem cell autocrine CXCL12/CXCR4 stimulates invasion and metastasis of esophageal cancer. PMID: 28193907 Ref: PAQR3 Inhibits the Proliferation and Tumorigenesis in Esophageal Cancer Cells. PMID: 28548040 |
Ref: RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. PMID: 29379302 Ref: miR302a inhibits the proliferation of esophageal cancer cells through the MAPK and PI3K/Akt signaling pathways. PMID: 29456742 Ref: Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades. PMID: 29693162 Ref: IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment. PMID: 29976575 Ref: Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways. PMID: 30050135 |