Primary Site >> Colorectal Cancer
Gene >> MAP2K5
|
|
|
|
|
|---|---|---|---|---|
|
Ref: Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas. PMID: 17143621 |
Ref: Mitogen/extracellular signal-regulated kinase kinase-5 promoter region polymorphisms affect the risk of sporadic colorectal cancer in a southern Chinese population. PMID: 21861603 Ref: Expression of the phosphorylated MEK5 protein is associated with TNM staging of colorectal cancer. PMID: 22458985 |
Ref: Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2. PMID: 24801835 |
Ref: SATB2 suppresses the progression of colorectal cancer cells via inactivation of MEK5/ERK5 signaling. PMID: 25662172 Ref: Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-kappaB activation. PMID: 25855966 |
Ref: Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation. PMID: 26959608 Ref: MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism. PMID: 27144434 Ref: MEK5 overexpression is associated with the occurrence and development of colorectal cancer. PMID: 27160304 |