Primary Site >> Liver Cancer
Gene >> LOX
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Ref: Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro. PMID: 17570221 |
Ref: A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase. PMID: 20126469 Ref: Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. PMID: 20386571 Ref: CaMKII Inhibitor KN-62 Blunts Tumor Response to Hypoxia by Inhibiting HIF-1alpha in Hepatoma Cells. PMID: 21165333 |
Ref: Chebulagic acid synergizes the cytotoxicity of doxorubicin in human hepatocellular carcinoma through COX-2 dependant modulation of MDR-1. PMID: 21801152 Ref: 5-Lipoxygenase contributes to the progression of hepatocellular carcinoma. PMID: 21833474 |
Ref: Liver-specific overexpression of matrix metalloproteinase 9 (MMP-9) in transgenic mice accelerates development of hepatocellular carcinoma. PMID: 21681821 Ref: Lipid metabolism enzyme 5-LOX and its metabolite LTB4 are capable of activating transcription factor NF-kappaB in hepatoma cells. PMID: 22293202 Ref: Hepatitis B virus X protein drives multiple cross-talk cascade loops involving NF-kappaB, 5-LOX, OPN and Capn4 to promote cell migration. PMID: 22355367 Ref: The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis. PMID: 22796152 Ref: The functional interaction between Acyl-CoA synthetase 4, 5-lipooxygenase and cyclooxygenase-2 controls tumor growth: a novel therapeutic target. PMID: 22808264 |
Ref: Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells. PMID: 23471881 Ref: Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues. PMID: 23560895 Ref: Coevolution of the tumor microenvironment revealed by quantum dot-based multiplexed imaging of hepatocellular carcinoma. PMID: 23837765 |
Ref: Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin beta1. PMID: 24472554 Ref: Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance. PMID: 24573150 |
Ref: Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma. PMID: 26048020 Ref: Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin beta1/GSK3beta/beta-Catenin Signaling Pathway. PMID: 26280346 Ref: Roles of E-cadherin in Hepatocarcinogenesis PMID: 29787164 |
Ref: Antitumour activity of an inhibitor of miR-34a in liver cancer with beta-catenin-mutations. PMID: 25792709 |
Ref: Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice. PMID: 28422962 |
Ref: Nigella sativa L. and Its Bioactive Constituents as Hepatoprotectant: A Review. PMID: 29701149 |